LOCUS       NZ_MPOH02000005        26719 bp    DNA     linear   CON 03-MAY-2024
DEFINITION  Streptomyces phaeoluteigriseus strain DSM 41896 Scaffold_5, whole
            genome shotgun sequence.
ACCESSION   NZ_MPOH02000005
VERSION     NZ_MPOH02000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces phaeoluteigriseus
  ORGANISM  Streptomyces phaeoluteigriseus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
REFERENCE   1  (bases 1 to 510511)
  AUTHORS   Salih,T.S., Algora Gallardo,L., Melo Santos,T., Filgueira
            Martinez,S. and Herron,P.R.
  TITLE     Draft genome sequence of Streptomyces phaeoluteigriseus type strain
            DSM41896
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 510511)
  AUTHORS   Salih,T.S., Algora Gallardo,L., Melo Santos,T., Filgueira
            Martinez,S. and Herron,P.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2017) Strathclyde Institute of Pharmacy and
            Biomedical Sciences, University of Strathclyde, 161 Cathedral
            Street, Glasgow G40RE, United Kingdom
REFERENCE   3  (bases 1 to 510511)
  AUTHORS   Schniete,J.K., Salih,T., Algora Gallardo,L., Martinez Fernandez,S.
            and Herron,P.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-NOV-2016) Strathclyde Institute for Pharmacy and
            Biomedical Sciences, University of Strathclyde, 161 Cathedral
            Street, Glasgow G40RE, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 26-JAN-2017
            Assembly Method                   :: SPAdes v. 3.9; MeDuSa v. 1.6
            Genome Coverage                   :: 65.0x
            Sequencing Technology             :: IonTorrent
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001896135.2-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:12:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,918
            CDSs (total)                      :: 7,837
            Genes (coding)                    :: 6,622
            CDSs (with protein)               :: 6,622
            Genes (RNA)                       :: 81
            rRNAs                             :: 3 (5S)
            complete rRNAs                    :: 3 (5S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 1,215
            CDSs (without protein)            :: 1,215
            Pseudo Genes (ambiguous residues) :: 0 of 1,215
            Pseudo Genes (frameshifted)       :: 907 of 1,215
            Pseudo Genes (incomplete)         :: 407 of 1,215
            Pseudo Genes (internal stop)      :: 30 of 1,215
            Pseudo Genes (multiple problems)  :: 120 of 1,215
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:00:38
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 239246
            Orig. end                         :: 265965
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MPOH02000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26719
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26719
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26719
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16719](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16719)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(25..36)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.83"
                     /tool="antismash"
     gene            complement(326..1351)
                     /locus_tag="BM536_RS04295"
                     /old_locus_tag="BM536_004275"
     CDS             complement(326..1351)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386177.1"
                     /locus_tag="BM536_RS04295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004275"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_073491705.1"
                     /transl_table=11
                     /translation="MPAKGKHRRPKSQRFTRSIAVAGTGGAALALPLMGASGAQAAPSQ
                     SATQAVSAASAVSSLPSHSSVSEKAAETVSVAQKSGKSATGAKTYTVQSGDYLSKIADE
                     QNVSGGWSRLYADNREAVGENPSLIHPGLKLSIGEKAATGTTKSPSTSSGSSTSSGSSA
                     SPKQSSGSSTKSSSSDSGSSDSAKSSSSKASTAQAAEKATASSGFALPVAGATVGTPYK
                     MSGSMWSSGYHTGVDFVVPTGTSLKAVGAGTVVSAGWGGAYGNQVVIKLADGYYAQYAH
                     LSSLSVSAGQSVSGGQQIGLSGATGNVTGPHLHFEIRTGPDYGSDIDPVAYLRSHGVSV
                     G"
     misc_feature    1335..1350
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.08"
                     /tool="antismash"
     regulatory      complement(1356..1513)
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    1639..1652
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 21.08"
                     /tool="antismash"
     gene            2576..3372
                     /locus_tag="BM536_RS04300"
                     /old_locus_tag="BM536_004280"
                     /pseudo=""
     CDS             2576..3372
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069689.1"
                     /locus_tag="BM536_RS04300"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004280"
                     /product="tyrosine-protein phosphatase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTQQIPSTEPELAGVRNFRDVGGLPTVDGRRVRHGVLYRSGHLAH
                     ATDEDVAFLSSLGLHTVFDFRNAADQKLEGPDVELPGVRNVNLPLSDPADGAEFWKMVR
                     EGDIEQLREILGDGRAAGRMIASYRSIMKERTGEHSRVLHSLAEDSVPALMHCAAGKDR
                     AGLSIAVTLLALGVERDAILADYLESSAKHRRYKVRRSGTSAAAYSPEVMELLDPLFDA
                     RAEYLTAAFETVEETWGVSTPTWSRASA"
     gene            complement(3399..3521)
                     /locus_tag="BM536_RS04305"
                     /old_locus_tag="BM536_004285"
     CDS             complement(3399..3521)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009329167.1"
                     /locus_tag="BM536_RS04305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004285"
                     /product="DUF6126 family protein"
                     /protein_id="WP_073499749.1"
                     /transl_table=11
                     /translation="MTDIEEKFPRSLWIRLIIYIAVGHVFAGFLWLLFEVGAKR"
     gene            complement(3518..4141)
                     /locus_tag="BM536_RS04310"
                     /old_locus_tag="BM536_004290"
     CDS             complement(3518..4141)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006133819.1"
                     /locus_tag="BM536_RS04310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004290"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_073499747.1"
                     /transl_table=11
                     /translation="MSHPASEPGPEPADDLGVVAPQLRALRRRASLTLEAAARAAGLSP
                     AHLSRLETGQRQPSLPMLLALARVYGTTVSELLGERVADRDAVVRAADMEPTHAGGWTY
                     WQSGASGRGMQALRVQVPYGSQGDIVRVHPGEEWLHVLRGRLRLRLGDTTHLLGAGDSA
                     HFDSLTPHRIAAQDPDGVDLLFVHTLLQSPTAALCLGPTPGETP"
     misc_feature    complement(4147..4167)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 22.29"
                     /tool="antismash"
     misc_feature    complement(4173..4186)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.16"
                     /tool="antismash"
     gene            complement(4222..5607)
                     /locus_tag="BM536_RS04315"
                     /old_locus_tag="BM536_004295"
     CDS             complement(4222..5607)
                     /NRPS_PKS="Domain: Aminotran_3 (41-363). E-value: 1.3e-87.
                     Score: 286.0. Matches aSDomain:
                     nrpspksdomains_BM536_RS04315_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494124.1"
                     /locus_tag="BM536_RS04315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004295"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_073499745.1"
                     /sec_met_domain="Aminotran_3 (E-value: 8.4e-87, bitscore:
                     286.2, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTEFDLGALLAERGAERYELHGRYLNHQLPRMLHTIGFDKVYER
                     GEGAYFWDADGNDYLDMLAGFGVMGLGRHHPVVRKALHDVLDASLADLTRFDCQPLPGL
                     LAEKLLAHSPHLDRVFFGNSGTEAVETALKFARYATGKPRVLYCDHAFHGLTTGSLSVN
                     GEGGFRDGFAPLLPDTAVPLGDLDALARELRKGDVAALIVEPIQGKGVHEAPPGHLRAA
                     QELLHRHRALLIADEVQTGLGRTGDFYAYQHEDGVEPDLVCVAKALSGGYVPVGATLGK
                     DWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMENEQIVAGARLTGDLLKSRLT
                     ALIDKYELLADVRGRGLMIGIEFGKPRSLKLRSRWAMLQAARKGLFAQMVVVPLLQRHR
                     ILTQVSGDHLEVIKLIPPLVVGEPEVDRFVDAFTEVMDDAHNGGGLVWDFGRTLIKQAV
                     ANR"
     aSDomain        complement(4519..5484)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM536_RS04315_Aminotran_3.1"
                     /evalue="1.30E-87"
                     /label="BM536_RS04315_Aminotran_3.1"
                     /locus_tag="BM536_RS04315"
                     /protein_end="363"
                     /protein_start="41"
                     /score="286.0"
                     /tool="antismash"
                     /translation="VYERGEGAYFWDADGNDYLDMLAGFGVMGLGRHHPVVRKALHDVL
                     DASLADLTRFDCQPLPGLLAEKLLAHSPHLDRVFFGNSGTEAVETALKFARYATGKPRV
                     LYCDHAFHGLTTGSLSVNGEGGFRDGFAPLLPDTAVPLGDLDALARELRKGDVAALIVE
                     PIQGKGVHEAPPGHLRAAQELLHRHRALLIADEVQTGLGRTGDFYAYQHEDGVEPDLVC
                     VAKALSGGYVPVGATLGKDWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMENE
                     QIVAGARLTGDLLKSRLTALIDKYELLADVRGRGLMIGIEF"
     gene            complement(5604..7505)
                     /gene="dxs"
                     /locus_tag="BM536_RS04320"
                     /old_locus_tag="BM536_004300"
     CDS             complement(5604..7505)
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386171.1"
                     /locus_tag="BM536_RS04320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004300"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_094102541.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 2.2e-111,
                     bitscore: 366.2, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.6e-07, bitscore:
                     24.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILENIRQPRDLKALSEAELGELCGEIREFLVHAVARTGGHLGP
                     NLGVVELTVALHRAFESPVDRILWDTGHQSYVHKLLTGRQDFSKLRGKGGLSGYPSREE
                     SEHDVIENSHASTALGWADGLAKARQVRGEKGHVVAVVGDGALTGGMAWEALNNIAAAK
                     DRPLIIVVNDNERSYAPTIGGLADHLATLRTTDGYEKVLAWGKDVLLRTPVVGHTVYES
                     LHGAKKGFKDAFAPQGMFEDLGLKYVGPVDGHDIGAVESALRRAKRFHGPVLVHCLTEK
                     GRGYEPALAHEEDHFHTVGVMDPLTCAPLAPAGAPSWTSVFGDEIVRIGEERDDVVAIT
                     AAMLHPVGLGEFAARFPGRVWDVGIAEQHAAVSAAGLATGGLHPVVAVYATFLNRAFDQ
                     LLMDVALHRCGVTFVLDRAGVTGVDGASHNGMWDMSVLQVVPGLRIAAPRDADQLRAQL
                     REAVAVDDAPTLIRFPKESVGPRIPAVGHVGGMDVLRRGAAPEVLLVAVGVMAPACLRA
                     AELLEARGIDCTVVDPRWVKPVDPALPGLAADHRLVAVVEDNSRAAGVGSAVALALGDA
                     EVDVPVRRFGIPEQFLAHAKRAEVLADIGLTPVEIAGRISASLAVCDADGPVKETTE"
     gene            complement(7534..8327)
                     /locus_tag="BM536_RS04325"
                     /old_locus_tag="BM536_004305"
                     /pseudo=""
     CDS             complement(7534..8327)
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031167.1"
                     /locus_tag="BM536_RS04325"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004305"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTAISLGIPEVPVRPIAARRVSRRIQVGPVAVGGGAPVSVQSMTT
                     TRTSDIGATLQQIAELTASG"
     gene            complement(8332..9354)
                     /gene="hpnH"
                     /locus_tag="BM536_RS04330"
                     /old_locus_tag="BM536_004310"
     CDS             complement(8332..9354)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386169.1"
                     /locus_tag="BM536_RS04330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004310"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_073495867.1"
                     /sec_met_domain="PF04055 (E-value: 1.8e-18, bitscore: 62.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 2.2e-09, bitscore: 31.9,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSIKVATYLAEQKLRKREKFPLIVELEPLFACNLACEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIHEIVRQLVARRKYVF
                     LCTNAMLMRKKMDRFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVEAIKEAKRRGF
                     RVTTNSTFFNTDTPQTIIEVLNFLNDDLKVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FKKAFSGGNRRRWRLNHSPLFLDFLEGKVDFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRELIEETDWDKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAMRETVSGNRE
                     "
     gene            complement(9360..10001)
                     /locus_tag="BM536_RS04335"
                     /old_locus_tag="BM536_004315"
     CDS             complement(9360..10001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431357.1"
                     /locus_tag="BM536_RS04335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004315"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_094102542.1"
                     /transl_table=11
                     /translation="MNAQPAPAPLLIACALGIEHLALRMGDRGGAGGPVTVLRTGMGPK
                     AAERSVTRVLADPVLGGAAVLATGFCAGLAPGMHPGDLVVAEETRDPLGTVPCVNTDLL
                     VKELVRTLPGRTVHTGPLTGSDHVVRGPERSDLLATGAIAVDMESAATLLSAVRAGTRP
                     VAAVRVVVDAPEHELVRIGTVRGGISAFRVLRSVLPAFFEWHRNVLLPRR"
     gene            complement(10001..12013)
                     /gene="shc"
                     /locus_tag="BM536_RS04340"
                     /old_locus_tag="BM536_004320"
     CDS             complement(10001..12013)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019985322.1"
                     /locus_tag="BM536_RS04340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004320"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_094102543.1"
                     /sec_met_domain="T2TS (E-value: 1.2e-147, bitscore: 487.6,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGALPPRAAAASETRIDIPAAAGVQEAAVRAVRRATD
                     FLLARQDVEGWWKGDLETNVTMDAEDLLLRQFLDIQDESTTRAAALFIRGEQRADGTWA
                     TFHGGPGDLSATIEAYVALRLAGDEPHAPHMAKASAWVRDQGGIAAARVFTRIWLALFG
                     WWKWEDLPELPPELLYFPKWFPLSIYNFGCWARQTIVPLTVVSAKRPVRPAPFPLDELH
                     TDPADPNPPRPLAPVASWDGLFQRLDKVVRGYRKVAVRRLRKAALNSAARWIVERQEND
                     GCWGGIQPPAVYSVIALYLLGYDLEHPVMREGLKSLDRYAVWREDGARMIEACQSPVWD
                     TCLATIALADAGVPADHPQLVKAADWMLGEQIVRPGDWSVRRPGLPPGGWAFEFHNDNY
                     PDIDDTAEVVLALRRVRHHDPDRVESAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNR
                     LPFCDFGEVIDPPSADVTAHVVEMLAFEGLSHDPRTRRGITWLLAEQEPEGSWFGRWGV
                     NYIYGTGSVVPALTAAGLPARHPAIRRAVGWLERVQNEDGGWGEDLRSYQDSTRWSGRG
                     ASTASQTAWALMALLAAGEKDSKAVERGVAWLAETQREDGSWDEPQFTGTGFPWDFSIN
                     YHLYRQVFPLTALGRYVHGEPLVVKAPSPAEAEGR"
     misc_feature    12121..12136
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.62"
                     /tool="antismash"
     misc_feature    complement(12124..12139)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.27"
                     /tool="antismash"
     gene            complement(12132..13196)
                     /locus_tag="BM536_RS04345"
                     /old_locus_tag="BM536_004325"
     CDS             complement(12132..13196)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972234.1"
                     /locus_tag="BM536_RS04345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004325"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_170109880.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7e-59, bitscore:
                     194.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPAEKAARRTAVDVTALLERGRTLATPVLRAAVDRLVSPMDTVA
                     AYHFGWIDAQGNPTDGDGGKAVRPALAVLSAQVTGAAPEVGVPGAVAVELVHNFSLLHD
                     DLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALAGEVLLELGTVEAGRAARRLTTASR
                     ALIDGQAQDMSYEHRDRVSVEECLEMEGNKTGALLACASSIGAVLGGADARTADTLERY
                     GHHLGLAFQAVDDLLGIWGDPEATGKQTWSDLRQRKKSLPVVAALAAGGPASEQLGEML
                     AADAKRQDFANFSEEEFAARAALIEEAGGREWTAGEARRQHTIAIEALNAVDMPEQVRD
                     QFTALADFVVVRKR"
     gene            complement(13271..14728)
                     /gene="hpnE"
                     /locus_tag="BM536_RS04350"
                     /old_locus_tag="BM536_004330"
     CDS             complement(13271..14728)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994384.1"
                     /locus_tag="BM536_RS04350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004330"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_073495863.1"
                     /sec_met_domain="DAO (E-value: 2.5e-10, bitscore: 35.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDEPRSDIPETSGRDAVVIGGGLAGITAALALADAGVRVTLLES
                     RPRLGGLAFSFQRDGLTVDNGQHVYLRCCTAYRWFLDRIEGTALAPIQNRLDVPVVDLA
                     RPEGRRLGRLRRDELPVPLHLGRSLATYPHLSLADRARVGRAALALKGLDLADPALDAQ
                     DFGSWLTAHGQSARAVEALWDLVGVATLNAVAGDTSLALAAMVFKTGLLSDPGAADIGW
                     AHVPLGELHDRLARKALDSAGVRTEIRTRVTSVSAEDNGSWTVQVPGETLRADAVVLAV
                     PQRETYDLLPDGALDAPERLLDIGTAPILNLHVVYDRKVLDVPFLTALGTPVQWVFDRT
                     DASGLSTGRPEGPDEGRGGRRAGQYLAVSQSAAHEDIDAPVAALRERYLPELERLLPAA
                     RGATVRDFFVTRERTATFAPTPGVGRLRPGARTKASGLYLAGAWTATGWPATMESAVRS
                     GVSAADAALGALGRPRPRRLFAVEEAA"
     misc_feature    14852..14867
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.37"
                     /tool="antismash"
     gene            complement(14880..15830)
                     /gene="hpnD"
                     /locus_tag="BM536_RS04355"
                     /old_locus_tag="BM536_004335"
     CDS             complement(14880..15830)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994383.1"
                     /locus_tag="BM536_RS04355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004335"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_094102545.1"
                     /sec_met_domain="phytoene_synt (E-value: 7.3e-55, bitscore:
                     180.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 4.7e-68,
                     bitscore: 224.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTVESPPPVSAPVLAAYGYCETVTGQQARNFAYGIRLLPTAKR
                     RAMSALYAFSRRVDDIGDGALGGEVKSARLQDTRALLTRVRAGEVEEDDTDPVAVALAH
                     AARVFPIPLGGLDELIDGVLMDVRGETYETWDDLRTYCRCVAGAIGRLSLGVFGTEAGA
                     RGADRAPEYADTLGLALQLTNILRDVREDALGGRTYLPADDLAKFGCSAGFDGPTPPEG
                     SDFAGLVHFEVRRARALFAEGYRLLPLLDRRSGACVAAMAGIYRRLLDRIERDPEAVLR
                     GRVSLPGREKAYVAVRGLSGLDTRHVSRMSGRRQI"
     gene            complement(15827..16719)
                     /gene="hpnC"
                     /locus_tag="BM536_RS04360"
                     /old_locus_tag="BM536_004340"
                     /pseudo=""
     CDS             complement(15827..16719)
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010042802.1"
                     /locus_tag="BM536_RS04360"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004340"
                     /product="squalene synthase HpnC"
                     /pseudo=""
                     /sec_met_domain="PT_phytoene_like (E-value: 2.9e-08,
                     bitscore: 28.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPGTADAERGTLAKAADENFPVAPFFLPRDWREDLVAVYGFAR
                     LVDDIGDGDLAPGGADARLLGVPADEAEDRLVLLDAFEATCGASSTARPATPCCVA"
     gene            complement(17080..17862)
                     /locus_tag="BM536_RS04365"
                     /old_locus_tag="BM536_004345"
     CDS             complement(17080..17862)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330378.1"
                     /locus_tag="BM536_RS04365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004345"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_073495862.1"
                     /transl_table=11
                     /translation="MAEQAPGTRVPTVIAEDVHIVYRVNGARTGKGSATAALSRIVRRG
                     GEERGVRKVHAVRGVSFVAHRGEAIGLIGSNGSGKSTLLRAIAGLLPPESGKVYTDGQP
                     SLLGVNAALMNDLTGERNIVLGGLAMGMSREQIKERYQEIVDFSGINEKGDFVTLPMRT
                     YSSGMQARLRFSIAAAKDHDVLMIDEALATGDAKFRKRSEERIRELRGQAGTVFLVSHS
                     NKSIRDTCDRVLWLERGELRMDGPTEEVLREYEKFSGK"
     gene            complement(17855..18784)
                     /locus_tag="BM536_RS04370"
                     /old_locus_tag="BM536_004350"
     CDS             complement(17855..18784)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994380.1"
                     /locus_tag="BM536_RS04370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004350"
                     /product="ABC transporter permease"
                     /protein_id="WP_073495860.1"
                     /transl_table=11
                     /translation="MSETTHDGAVAVSAPPSPDEGLTAAQLAAKYGLAVSGARPPLREY
                     VGRLWGRRHFILAFSQAKLTAQYSQAKLGQLWQVATPLLNAAVYFMIFGVILNASRGME
                     KEVYIPFLVTGVFVFTFTQSSVMSGVRAISGNLGLVRALHFPRAALPISFALQQLQQLL
                     YSMIVLFLVVIGFGSYPDASWILIVPALVLQFCFNTGLALVFARAGAKTPDLAQLMPFV
                     MRTWMYASGVMFSIPVFLADKPQWMANVLQWNPAAIYMDLVRFALIDEYGSENLPQHVW
                     AVAGGWAALFAIGGFVYFWQAEERYGRG"
     gene            complement(18882..19763)
                     /locus_tag="BM536_RS04375"
                     /old_locus_tag="BM536_004355"
     CDS             complement(18882..19763)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031159.1"
                     /locus_tag="BM536_RS04375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004355"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_073495859.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 7.8e-14,
                     bitscore: 46.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGAVIITMGNRPEELRALIDSVAKQDGDPVEVVVVGNGSPVPD
                     VTEFSPHVRTVELPENLGIPGGRNVGTEAFGPSGRDVDILMFLDDDGLLARHDTARLCR
                     EAFAADPELGIISFRIADPDTGVTQRRHVPRLRAADPMRSSRVTTFLGGANAVRTRVLA
                     EVGGLPDEFFYAHEETDLAWRALDAGWMINYRSDMVLHHPTTAPSRHAVYHRMVARNRV
                     WLARRNLPAPLVPVYLGVWLLLTLLRRPSRSALKAWFGGFREGWATPCGPRRPMKWRTV
                     WRLTRLGRPPVI"
     gene            complement(19772..20551)
                     /locus_tag="BM536_RS04380"
                     /old_locus_tag="BM536_004360"
     CDS             complement(19772..20551)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="BM536_RS04380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004360"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_073495870.1"
                     /transl_table=11
                     /translation="MSRPSVAELRPVVHPAGVKDRRSGEHWMGRLYMREVSLRVDRYLV
                     NTRVTPNQLTYLMTVFGVLAAPALLVPGITGAVLGLVCVQMYLLLDCVDGEIARWKKQY
                     SLGGVYLDRVGAYLTDAAVLVGFGLRAADLWGTGRIDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQGGLPPVKETASEPRSSGMALARRAAAALKFHRLVLGMEASLLILVLAIVDQ
                     TRGDLFFSRLGVAVLAGIALLQTVLHLVSILASSRLR"
     gene            complement(20529..21590)
                     /locus_tag="BM536_RS04385"
                     /old_locus_tag="BM536_004365"
     CDS             complement(20529..21590)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494151.1"
                     /locus_tag="BM536_RS04385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004365"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_073495857.1"
                     /sec_met_domain="Fe-ADH (E-value: 5.4e-21, bitscore: 69.6,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 8.5e-09, bitscore:
                     29.8, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRPGALDDLVGVLADERISHSGKLAIAVSG
                     GSGARLRERLSPSLPGATWYEVGGGTLDDAVRLAGDIKAGHYDAVVGLGGGKIIDCAKF
                     AAARVGLALVAVPTNLAHDGLCSPVATLDNDAGRGSYGVPNPIAVVIDLDVIREAPVRY
                     VRAGIGDAVSNISAIADWELAHRVKGEKIDGLAAAIARQAGEAVLRHPGGIGDTGFLQV
                     LAEALVLSGIAMSVSGDSRPSSGACHEINHAFDLLYPKRAAAHGEQCGLGAAFAMYLRG
                     AHEESVYMAEVLRRHGLPVLPDEIGFTTDEFVKVVEFAPQTRPGRYTILEHLDLKTEQI
                     KDTYADYVKAIGS"
     gene            complement(21578..22330)
                     /locus_tag="BM536_RS04390"
                     /old_locus_tag="BM536_004370"
     CDS             complement(21578..22330)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="BM536_RS04390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004370"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_073495855.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.3e-11, bitscore:
                     39.1, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDSLPKALVPVGPAGIEGEPTVLDLTLG
                     NFAEIGLTEVAVIVGYRKEAVYERKAALEAKYGLKLTLIDNDKAEEWNNAYSLWCGRDA
                     LKDGVILANGDTVHPVSVERTLLAARGEGRKIILALDTVKSLADEEMKVVVDPAKGMTK
                     ITKLMDPAEATGEYIGVTLIEGDAAPELADALKTVWETDPQQFYEHGYQELVNRGFRID
                     VAPIGDVSWVEIDNHDDLARGREIACQY"
     gene            complement(22327..24139)
                     /locus_tag="BM536_RS04395"
                     /old_locus_tag="BM536_004375"
                     /pseudo=""
     CDS             complement(22327..24139)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="BM536_RS04395"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004375"
                     /product="DUF5941 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSTAILTGQPVPGSSIEADLRSLGFDVRTATDAADAETLLAAVPG
                     DQRVAVVDTRFVGHRHALRLGLTDPRFPLAAIPGAVTAQPAGRQALTRALARENSANGG
                     TVLAVDSLADRIVTALDADGGEVHRPELGSLVAAVPADPQARNEARQAVSAVDDETVRL
                     KSAVKARDGFFTTFCISPYSRYLARWCARRGLTPNQVTTASLITALIAAGCAATGTRGG
                     YVAAGLLLLFSFVLDCTDGQLARYSLQYSTLGAWLDATFDRAKEYAYYAGLALGAARGG
                     DDVWALALGAMVLQTCRHVVDFSFNEANVDSTAATANTSPTAALSGKLDSVGWTVWARR
                     MIVLPIGERWAMIAVLTAATTPRITFYVLLVGCAFAATYTTAGRLLRSLTRKARRTDRA
                     AQALADLADSGPTAGLLVRFLPGGGAADGDPQRSRRCRARHARRLAVGTELVGRADGRC
                     LCPAVRRSRRPPPQGRPRLARPAGVPRRRVRHGADPRGEGGCERSATGGFRAGCRCRLP
                     SLRHGVPHPRQRRSAAGLAGARCRGTGGADAARGRTGRGAHRPAVHGRAHGARRGRRPR
                     GARREHPLLGRRPPGGRPVRTR"
     misc_feature    complement(24334..24348)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.6"
                     /tool="antismash"
     gene            24439..25410
                     /gene="galE"
                     /locus_tag="BM536_RS04400"
                     /old_locus_tag="BM536_004380"
     CDS             24439..25410
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (65-182). E-value:
                     3.2e-12. Score: 38.0. Matches aSDomain:
                     nrpspksdomains_BM536_RS04400_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676194.1"
                     /locus_tag="BM536_RS04400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004380"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_073495853.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.7e-18, bitscore:
                     61.5, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.2e-11,
                     bitscore: 39.1, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVARAMTGAGERVVVLDDLSAGVPGRLPADV
                     PLVAGSALDAGLLKRVLAEHAVTGVVHLAARKQVAESVARPTRYYRENVGGLATLLEAV
                     AEAGVRRFLFSSSAAVYGNPDVDLITEDTPCSPVNPYGETKLAGEWLVRAAGEAHGIAT
                     TCLRYFNVAGAAEPALADTGVFNIVPMVFDRLTRDEAPRIFGDDYPTPDGTCVRDYIHV
                     ADLAEAHLAAARRLTAPDVRGDLTVNIGRGEGVSVRELVTLIGEVTGDPRPALVEGRRP
                     GDAPRAVASAALAARELGWTASRGMREMVASAWRGWQLHHGG"
     CDS_motif       24442..24528
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BM536_RS04400_0001"
                     /evalue="1.40E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="BM536_RS04400"
                     /protein_end="30"
                     /protein_start="1"
                     /score="17.8"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVARAMTGAGERVVVL"
     aSDomain        24634..24984
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BM536_RS04400_NAD_binding_4.1"
                     /evalue="3.20E-12"
                     /label="BM536_RS04400_NAD_binding_4.1"
                     /locus_tag="BM536_RS04400"
                     /protein_end="182"
                     /protein_start="65"
                     /score="38.0"
                     /tool="antismash"
                     /translation="AVTGVVHLAARKQVAESVARPTRYYRENVGGLATLLEAVAEAGVR
                     RFLFSSSAAVYGNPDVDLITEDTPCSPVNPYGETKLAGEWLVRAAGEAHGIATTCLRYF
                     NVAGAAEPALADT"
     misc_feature    25432..25446
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.57"
                     /tool="antismash"
     misc_feature    complement(25461..25475)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            25548..26483
                     /locus_tag="BM536_RS04405"
                     /old_locus_tag="BM536_004385"
     CDS             25548..26483
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009339288.1"
                     /locus_tag="BM536_RS04405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BM536_004385"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_073495851.1"
                     /transl_table=11
                     /translation="MGAGHDHGHTHVPTTGTAAAAYRGRLRAALSITLTVMVVEIVGGV
                     LADSLALIADAAHMATDALGLGMALLAIHFAGRPPTGNRTFGYARAEILAALANCLLLL
                     GVGGYVVYEAVQRFFTPAPTEGGLMIVFGGIGLAANMVSLSLLMRGQADSINVRGAFLE
                     VAADALGSVAVLVSAVVILTTGWQAADPVASLVIGLMIVPRTVKLLRETLDVLLEAAPK
                     GVDMAEVRTHMLALDGVEDVHDLHAWTITSGMPVLSAHVVVRSDVLDAIGHEKMLHELQ
                     GCLGDHFDVAHCTFQLEPSGHAQHEARLCH"
     misc_feature    26505..26518
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.57"
                     /tool="antismash"
ORIGIN
        1 tgagacggac ggggcgcgat gcgggaaagc gcttgccgct cttttcgatc actgtgtccc
       61 tgccccgccc cgcctgtcga cacctcgggc acacccgcca caagaccgca atggaacgat
      121 catgagcgcg caaagtcgaa cagatgcgga gcgggtgccg gggggcgggg agtgccggtg
      181 cgggcgtccg tgcgggagca ggtgcgggca cctgcgtgcg ggcatgcgag cgcccaggcg
      241 cgcgggcgtg tggaaacacc gaaggccgac ccgggatcgg ggtccggcct tcgacggcgt
      301 gtcaggcggg aggtcgagcg ctacgtcagc cgacggagac gccgtgcgag cgcaggtagg
      361 cgacggggtc gatgtccgag ccgtagtcgg gaccggtacg gatctcgaag tgcaggtgcg
      421 ggccggtcac gttgccggtc gcaccggaca ggccgatctg ctgaccgccg gagacggact
      481 ggccggccga gacggagagc gaggacaggt gggcgtactg ggcgtagtag ccgtcggcga
      541 gcttgatgac gacctggttg ccgtacgcgc cgccccagcc cgcggagacg accgtgcccg
      601 cgccgacggc cttgagcgag gtgccggtcg ggacgacgaa gtcgacgccg gtgtggtaac
      661 cgctggacca catgctgccg gacatcttgt acggggtgcc gacggtcgca cccgccaccg
      721 ggagggcgaa gccactggag gcggtggcct tctcggcagc ctgcgccgtg gacgccttcg
      781 acgaggagga cttcgcggag tccgacgagc ccgagtccga ggaggacgac ttcgtggagg
      841 agcccgagga ctgcttcggc gaggccgacg aaccggacga agtagatgaa ccggacgaag
      901 tggacggcga cttggtcgtg ccggtcgcgg ccttctcccc gatcgagagc ttcagtcccg
      961 ggtggatcag cgacgggttc tcgccgacgg cctcacggtt gtccgcgtag agccggctcc
     1021 agccgccgct gacgttctgc tcgtccgcga tcttggagag gtagtcgccc gactgcaccg
     1081 tgtaggtctt ggcgcccgtg gcggacttcc cggacttctg cgccacggaa acggtctcgg
     1141 cggccttttc cgaaacagag gagtgggagg gaagggagga aacggcggag gcggcggaaa
     1201 cggcctgcgt cgccgactgg gacggtgcgg cctgggcgcc ggaggccccc atcaagggga
     1261 gggcgagcgc ggcgccaccg gttccggcga cggcgatgga acgggtgaag cgctgggact
     1321 tcggacgacg gtgcttaccc ttggcgggca tgacgaattc ctctccggcg cctgcgaggt
     1381 gagctgtcgg gtgcggactg gagatgtccg gccgcgccga ggcgcggctt tacccctagc
     1441 cgttccggag accggaacag gcggtactgc ctgtgggtcc cccgctcctg ccgttcacgg
     1501 gtgagtgtgc ggtctccggg cggcggcagg attgggcgtc cgtccggatt gggtggaacg
     1561 taagcgacca cgacgcacag gtacaagcga aggttgcact caccgcacgc ttctcttgat
     1621 cccctgtgag aattcccggt caccctgcgt gcatcgagag gccgttcttc ccacgaacgc
     1681 ccttgggaaa cagccgtatt acgtgcacat gacgggcgac tcatagtcac gaatatgacg
     1741 ctgctcacgt gacatgtccc cagatcccct tattacagag cgagttgtga cgaaggatct
     1801 aattcggaca gaacccccag atgcgacgct gccggataac cgtcgcatca agaccaccat
     1861 gcggcccggc gctcaaccag tggcgcatca gcatcgcacc ccggtcaact tcgtccattt
     1921 cacggcattc gcacaccgtt gccgggtcga gccccggcgc tcctggacgt cctggcgcac
     1981 ggagtgcagt acgagtcgat tgcacagttc cgtccgcttt cgtccgggct ggaaccgaac
     2041 ccagccgggg tgggccgggg cagccgactg gcagggtcgg ccgtcatcgc ccgggcgacc
     2101 ctgacccggc cgtgccccgc tcggacaact ccctctcgaa ggccgccact cgggcaccac
     2161 ggtcgggcga ggccatcgcc cgaccgagcc caccagaatc cggcaccgcc gcccgggcgg
     2221 ctccctcgcc tcgggccccc gccccctcac acgcggactg ccaccccggc gacccgccac
     2281 cccggccggg ccccacagcc ggcactcccc ccgtccgcaa ggggcatcac ccgcccgggt
     2341 gccgcccctc gagccaccgg ccgagggcct cgcccggccg aggcgacccc gatcatgcgc
     2401 ccccgctcct cccccgcccg ccccggtccg acgtacacgc caggtgccgc acaaccgccg
     2461 gagccccctg tggacaaccc gtttgccccg ggcatccatg tcgtatggtc agtgaggtgt
     2521 tccggtggcc atctcgagcc gcgccggccg ggaccgacga ccgggaggag cccccgtgac
     2581 gcagcagatc ccgtcgaccg agcccgagct ggccggagtg cgcaacttcc gggacgtggg
     2641 cggcctgccg accgtcgacg gccggcgcgt ccgccacggc gtgctgtacc gcagcggcca
     2701 cctcgcgcac gccaccgacg aggacgtcgc gttcctctcc tcgctgggat tgcacacggt
     2761 cttcgacttc cgcaacgcgg cggaccagaa gctggagggc cccgacgtcg agctgccggg
     2821 cgtgcgcaat gtgaacctgc cgctctccga cccggcggac ggcgccgagt tctggaagat
     2881 ggtccgcgaa ggcgacatcg agcagctgcg cgagatcctc ggcgacggca gggcggccgg
     2941 ccggatgatc gcctcctacc gctcgatcat gaaggagcgt acgggcgagc actcccgcgt
     3001 cctgcactcc ctcgcggagg acagcgtccc ggcgctgatg cactgcgcgg cgggcaagga
     3061 ccgcgccggc ctgtccatcg ccgtgaccct gctcgccctg ggtgtggagc gcgacgcgat
     3121 cctggccgac tacctggagt ccagcgccaa gcaccgccgc tacaaggtgc gccgcagcgg
     3181 cacctccgcc gcggcgtact cccccgaggt catggagctg ctcgaccccc tcttcgacgc
     3241 ccgtgccgag tacctgacgg ccgcgttcga gaccgtcgag gagacctggg gcgtgtcgac
     3301 acctacctgg agcagggcct cggcctgacg cctcggactc gcgagcggct ccgcgagcgc
     3361 ctgctcgact gagcaccccg ccggccgagg gccgtcggct accgcttggc gccgacctcg
     3421 aacagcagcc acaggaaccc ggcgaagaca tgccccaccg cgatgtagat gatcagccgg
     3481 atccacaggc tcctggggaa cttctcctcg atgtcggtca tggcgtctct ccaggggtgg
     3541 ggccgaggca cagcgcggcc gtcgggctct gcaacagagt gtggacgaac agcaggtcga
     3601 ccccgtcggg gtcctgggcg gcgatgcggt gcggggtcag cgagtcgaag tgcgcactgt
     3661 cccccgcgcc gagcaggtgc gtggtgtccc cgaggcgcag ccgcagccgt ccccgcagga
     3721 cgtgcagcca ctcctcgccc ggatgcaccc gcacgatgtc gccctgcgag ccgtacggca
     3781 cctgcacgcg cagcgcctgc atgccccgcc cggaggcgcc ggactgccag taggtccagc
     3841 cgcccgcgtg ggtgggctcc atgtcggcgg cgcgtacgac ggcgtcccgg tcggcgaccc
     3901 tctcgccgag gagttcggag acggtcgtac cgtagacgcg ggcgagtgcg agcagcatgg
     3961 gcagcgaggg ctggcgctgc ccggtctcca ggcgcgagag gtgggccggt gacagcccgg
     4021 cggcgcgggc cgcggcctcc agggtgaggg aggcgcgccg gcgcagggcg cggagctggg
     4081 gcgcgacgac acccaggtcg tccgccggtt cgggcccggg ctcggaggcg gggtggctca
     4141 tgcctccatt cagccggaac tttgcctctg cggcaaactt gttgcctcag aggcaaaaga
     4201 catcggcggg ggcgggagga cctaccggtt ggccaccgcc tgcttgatca gcgtcctgcc
     4261 gaagtcccag accagaccgc ccccgttgtg cgcgtcgtcc atcacctcgg tgaaggcgtc
     4321 cacgaaccgg tccacctccg gctcgcccac caccaacggc gggatcagct tgatcacctc
     4381 caggtggtcg ccggagacct gggtgaggat gcggtgccgc tggagcagcg ggacgaccac
     4441 catctgcgcg aacagcccct tgcgcgccgc ctggagcatg gcccagcgac tgcgcagttt
     4501 cagggatcgg ggctttccga actcgatgcc gatcatcagg ccccggccac ggacgtcggc
     4561 gagcagctcg tacttgtcga tcagcgccgt gagccgggac ttcagcaggt cgccggtcag
     4621 gcgggcgccc gcgacgatct gctcgttctc catgacggac agcacggcga gcccggccgc
     4681 catggcctgt gcgttggacc cgaagctcgc cgagtggacc agcacccggt ccatggacga
     4741 gtagaccttc ttgaagatcc aatccttccc gagcgtggcg ccgaccggca catagcctcc
     4801 ggagagggcc ttggcgacgc acaccaggtc cggttcgacg ccgtcctcgt gctggtaggc
     4861 gtagaagtcg ccggtccggc cgaggccggt ctgcacctcg tcggcgatga gcagcgccct
     4921 gtgccggtgc agcagctcct gggcggcacg cagatggccg ggcggggcct cgtgcacccc
     4981 cttgccctgg atcggctcga cgatcagcgc ggccacgtcg cccttccgca actcccgtgc
     5041 cagcgcgtcg agatcgccga ggggtacggc ggtgtcgggc agcagcggcg cgaagccgtc
     5101 gcggaacccg ccctcgccgt tgaccgacag ggaacccgtg gtgagcccgt ggaaggcgtg
     5161 gtcgcagtac aggaccctcg gcttcccggt ggcgtaccgg gcgaacttca gggcggtctc
     5221 cacggcctcc gtgccgctgt tgccgaagaa cacccggtcc aggtgcggac tgtgggcgag
     5281 cagcttctcg gccagcagtc cgggcagcgg ctggcagtcg aagcgcgtga ggtcggcgag
     5341 cgaggcgtcg aggacgtcgt gcagcgcctt gcggacgacg gggtggtggc ggcccaggcc
     5401 catcaccccg aacccggcga gcatgtccag gtagtcgttg ccgtccgcgt cccagaagta
     5461 cgcgccctcg ccccgctcgt agaccttgtc gaagccgatg gtgtgcagca tgcgcggcag
     5521 ttggtggttg aggtatctgc cgtgcagctc gtagcgttcg gctccgcgct cggccagcag
     5581 cgcgccgagg tcgaactccg tgctcattcc gttgtctcct tgacggggcc gtcggcgtcg
     5641 cagacggcca ggctcgcgct gatccgtccg gcgatctcga cgggcgtgag gccgatgtcg
     5701 gcgagcacct cggcccgctt agcgtgggcg aggaactgct ccgggatgcc gaaccgccgt
     5761 acgggcacgt cgacctcggc gtctccgagg gccagggcga cggccgaacc gacgcccgcg
     5821 gcacggctgt tgtcctcgac gacggccacc agacggtggt cggcggcgag gccgggcagg
     5881 gccgggtcga cgggtttcac ccagcgcggg tccaccaccg tgcagtcgat gccccgggcc
     5941 tccagcagtt cggcggccct gaggcaggcc ggtgccatga cgccgacggc gaccaggagg
     6001 acctccggcg ccgcgccgcg gcgcagtacg tccatgccac cgacgtggcc gacggccggg
     6061 atccgcggtc cgaccgactc cttcgggaag cggatcaggg tgggcgcgtc gtccacggcg
     6121 accgcttccc gcagttgcgc gcgcagttgg tcggcgtcgc gcggggccgc gatcctgagg
     6181 ccggggacga cctggaggac ggacatgtcc cacatgccgt tgtgggaggc gccgtccacc
     6241 ccggtcaccc cggcgcggtc gaggacgaac gtgacgccgc agcggtgcag ggccacgtcc
     6301 atcagcagct ggtcgaaggc ccggttgagg aaggtggcgt acacggcgac gacggggtgc
     6361 aggcccccgg tggccagccc ggccgcggac accgccgcgt gctgttcggc gatcccgacg
     6421 tcccacaccc ggccggggaa gcgggcggcg aactcaccga ggccgaccgg gtgcagcatg
     6481 gcggcggtga tcgccacgac gtcgtcgcgt tcctcgccga tccgcacgat ctcgtcgccg
     6541 aacacggacg tccaggaggg ggcgccggcc ggggcgagcg gtgcgcaggt cagcgggtcc
     6601 atcaccccga cggtgtggaa gtggtcctcc tcgtgcgcga gagcgggctc gtagccgcgg
     6661 cccttctcgg tcaggcagtg aaccagcacc ggcccgtgga agcgcttggc ccgccgcagc
     6721 gccgactcga cggccccgat gtcgtgcccg tcgacgggac cgacgtactt caggccgagg
     6781 tcctcgaaca tgccctgcgg cgcgaaggcg tccttgaagc ccttcttcgc gccgtgcagc
     6841 gactcgtaga cggtgtggcc gacgacgggc gtgcgcagca gtacgtcctt cccccaggcc
     6901 agcaccttct cgtagccgtc ggtggtgcgc agggtggcca ggtggtcggc gaggccgccg
     6961 atggtcgggg cgtaggagcg ttcgttgtcg ttgacgacga tgatcagcgg ccggtccttg
     7021 gcggccgcga tgttgttgag cgcctcccag gccatgccgc cggtgagcgc gccgtcgccg
     7081 acgaccgcga cgacgtggcc cttctcgccc cgcacctggc gggccttggc gaggccgtcg
     7141 gcccagccga gggcggtgga ggcgtggctg ttctcgatga cgtcgtgctc ggactcctcg
     7201 cgtgagggat agccggacag gccgcccttg ccccgcagct tggagaaatc ctgacgcccc
     7261 gtcagaagct tgtgcacata actctgatgg ccggtgtccc acaggatgcg gtcgaccggc
     7321 gactcgaagg cccggtgcag ggcgacggtc agttccacca cccccagatt gggcccgagg
     7381 tgtccgccgg tcctggcgac ggcgtgcacc aggaactccc tgatctcgcc gcacagttcg
     7441 ccgagttccg cctcggacag cgccttcagg tcgcgcggct gccgaatgtt ctccaggatc
     7501 gtcacgctcg ggccccctct cggtccgtgc tgttcaactc acggtgacgg ccggccctcc
     7561 ggaggcgacg ccgtcctgtt ccatccgctg gacgatcttc atcgcctcct cgatgagggt
     7621 ctccacgatc ctcgactcgg gcacggtctt gacgacctcg cccttcacga agatctgccc
     7681 cttgccgttg ccggaggcga ctcccaggtc cgcctcccgc gcctcgccgg ggccgttgac
     7741 cacacatccc atgaccgcga cccggagcgg gacctccatg ccctccagac ccgcggtgac
     7801 ctcctcggcc agcttgtaga cgtcgacctg ggcgcggccg caggacgggc aggagacgat
     7861 ttccagccca cgctgcctga ggttcagcga ctccaggatc tggatgccga ccttgacctc
     7921 ctccgcgggc ggcgcgctca acgacacccg gatcgtgtcc ccgatcccct gcgagagcag
     7981 ggcgccgaag gccacggccg acttgatcgt cccctggaac gccggacccg cctcggtcac
     8041 cccgaggtgc agcgggtagt cgcactgggc ggcgagctgg cggtaggcct cgatcatcac
     8101 caccgggtcg ttgtgcttga cggagatctt cagccggacg ccgtcagctc ggcgatctgc
     8161 tggagcgtcg cgccgatgtc ggacgtccgg gtcgtcgtca tcgactgcac ggacaccgga
     8221 gccccgcccc cgaccgccac cggtccgacc tggatccgcc gcgacacgcg ccgcgcggcg
     8281 atcggccgga ccggtacctc gggaatgccc aaggagatgg cggtcacagc gctactcgcg
     8341 gtttccggag acggtttcgc gcatggcccg cagggactcc ttgagcgagc ccatggtggc
     8401 gaggacggcg gtgggctcgt agccgcagtg cgccatgcag ttcgcgcagc gcgggtcctt
     8461 gccgcggccg tacttgtccc agtcggtctc ctcgatcagt tcccggtacg tcggcacata
     8521 gccgtcgctc atcaggtagc agggccgctg ccagccgaag agggagtagt tcgggatcgc
     8581 ccaggccgtg cacgggaaat cgaccttgcc ctccaggaag tccaggaaga gcggcgagtg
     8641 gttgagccgc cagcggcgcc tgtttccgcc ggagaaggcc ttcttgaaca gctcccgggt
     8701 ctgctccacg ccgaggaagt gctcctggtc gggagccttc tcgtaggcgt aggcgggcga
     8761 gatcatcatc tcgtcgacct tgaggtcgtc gttgaggaag ttgagcacct cgatgatggt
     8821 ctgcggggtg tcggtgttga agaaggtcga gttggtggtg acccggaagc cgcgccgctt
     8881 ggcctccttg atcgcctcca ccgcctcgtc gaacacgccc tccttggcga cggactcgtc
     8941 gtgccgctcg cgcagaccgt cgatgtgcac cgcgaaggcg aagtagggcg agggcgtgaa
     9001 cctgtccatc ttcttgcgca tcagcatggc gttggtgcag aggaagacgt acttcctcct
     9061 cgccaccaac tgccgcacga tctcgtggat ctgaggatgc atcagcggct cgccgccggc
     9121 gatggagacc atcggcgcac cggattcgag taccgcgccc acggcctggg cgaccggcat
     9181 gcgttgcttc agcacaccgg ccgggtgctg gatcttgccg cagccctcgc acgccaggtt
     9241 gcaggcgaag aggggttcca gctccacgat gagcggaaac ttctcccgct tgcggagctt
     9301 ctgttcagcc aagtacgtag cgaccttgat ggactggcgc agcggcatgg ccatctggct
     9361 cacctccggg ggagcagcac attgcggtgc cattcgaaga atgcaggcag gacggaacga
     9421 aggacgcgga acgccgatat tccaccgcgt accgtgccga tccggacgag ttcatgttca
     9481 ggagcgtcca cgaccacccg gacggccgca accgggcgcg tgcccgcgcg gacggcgctc
     9541 agcagcgtgg ccgccgactc catgtcgacc gcgatcgcgc cggtggcgag caggtcggac
     9601 cgctccgggc cgcgcaccac gtggtcggag ccggtcaggg ggccggtgtg gacggtgcgc
     9661 ccgggcaggg tgcgcacgag ttccttgacg agcaggtcgg tgttcacgca cggcacggtg
     9721 ccgagcgggt cacgggtctc ctcggcgacg acgaggtcgc cggggtgcat gccgggggcc
     9781 agtcccgcgc agaagccggt ggcgagcacc gccgccccgc cgagcaccgg gtcggcgagg
     9841 acccgggtga cggagcgctc ggccgccttc ggccccatgc cggtgcgcag gacggtcacc
     9901 ggcccgccgg ccccgccgcg gtcgcccatg cgcagcgcga ggtgctcgat gccgagcgcg
     9961 caggcgatca gcagcggggc gggggcgggc tgggcgttca tcagcgtcct tcggcctcgg
    10021 cgggagacgg tgccttcacg acgaggggct cgccgtggac gtaccggccg agcgcggtca
    10081 gcgggaacac ctgccggtac aggtggtagt tgatggagaa gtcccacggg aagccggtcc
    10141 cggtgaactg cggctcgtcc caggaaccgt cctcgcgctg ggtctcggcg agccaggcga
    10201 cgccccgctc gacggccttg gagtccttct ccccggccgc cagcagcgcc atcagcgccc
    10261 aggcggtctg ggaggcggtg gaggcgcccc ggccgctcca gcgtgtcgag tcctggtagg
    10321 agcgcaggtc ctcgccccag ccgccgtcct cgttctgcac ccgctccagc cagccgaccg
    10381 cccgccggat cgccgggtgc cgggcgggca gtccggcggc ggtgagcgcg ggcaccaccg
    10441 agccggtgcc gtagatgtag ttgacgcccc agcgcccgaa ccacgagcct tccggctcct
    10501 gttcggcgag tagccaggtg atgccgcgcc gggtgcgcgg atcgtgggag aggccctcga
    10561 acgcgagcat ctcgacgacg tgcgcggtga cgtccgcgga cggcgggtcg atgacctcgc
    10621 cgaagtcgca gaacggcagg cggttgggaa aggggctggt gttgtcgacg tcgaacgcgc
    10681 cccaggcgcc gttcctggac tgcatgccga ggttccagcg caccccgcgc ccgatcgcgc
    10741 tctccacccg gtccgggtcg tggtggcgga cccggcgcag cgcgaggacc acctcggcgg
    10801 tgtcgtcgat gtcggggtag ttgtcgttgt ggaactcgaa ggcccagcca ccgggcggga
    10861 gcccgggccg ccgtacggac cagtcgccgg gccgcacgat ctgctcgccc agcatccagt
    10921 cggccgcctt gaccagttgg gggtggtcgg ccggcacccc cgcgtcggcc agcgcgatgg
    10981 tggcgaggca ggtgtcccac acgggtgact ggcaggcctc gatcatccgc gccccgtcct
    11041 cgcgccacac cgcgtaccgg tccagcgact tgaggccctc gcgcatcacg gggtgttcga
    11101 ggtcgtagcc gagcaggtac agggcgatga ccgagtacac ggccggcggc tggatgccgc
    11161 cccagcagcc gtcgttctcc tgccgctcga cgatccagcg ggcggcggag ttcagggcgg
    11221 ccttgcgcag tctgcgcacc gcgaccttgc ggtagccgcg cacgaccttg tccagccgct
    11281 ggaacaaccc gtcccaactg gccaccggcg ccaggggcct gggcgggttg ggatcggccg
    11341 ggtcggtgtg cagttcgtcg agcgggaagg gcgccggacg caccgggcgc ttcgcggaga
    11401 cgacggtgag cggcacgatg gtctgccggg cccagcagcc gaagttgtag atgctgagcg
    11461 ggaaccactt cgggaagtag aggagttccg gcgggagttc ggggaggtcc tcccacttcc
    11521 accagccgaa cagcgccagc cagatccggg tgaagacccg ggcggcggcg atccctccct
    11581 ggtcgcggac ccaggcggag gccttcgcca tgtgcggcgc gtggggctcg tccccggcca
    11641 gccgcagggc gacgtacgcc tcgatggtgg cggagaggtc gccggggccg ccgtggaagg
    11701 tggcccaggt tccgtccgcg cgctgttcgc cgcggatgaa gagggcggcg gcgcgggtcg
    11761 tcgactcgtc ctggatgtcc aggaactgac ggagcagcag atcctcggcg tccatggtga
    11821 cgttcgtctc gaggtcgccc ttccaccagc cctcgacgtc ctgccgggcg agcaggaagt
    11881 cggtcgcgcg ccggaccgcg cgcacggcgg cttcttgtac cccggccgcc gcggggatgt
    11941 cgatacgggt ttcgctggcc gcggcagcgc ggggcgggag ggccccggtg cttccgtcgg
    12001 tcgtcgctgt catggcttcc ccttcgtgca gtgtgcatgg cgttgcgtct gctgtgggtc
    12061 cgccgtcgcc ggtgcgtctc ttcccgcgac accggccggc gactacgcga gggttattcg
    12121 accgatagtg atcatctctt tcgtacgacg acgaagtcgg cgagcgccgt gaactggtcc
    12181 cgcacctgct cgggcatgtc gacggcgttc agggcttcga tggcgatggt gtgctgacgg
    12241 cgtgcctccc cggcggtcca ctcgcggccg ccggcctcct cgatgagcgc ggcgcgggcc
    12301 gcgaactcct cctcggagaa gttcgcgaag tcctggcgct tggcgtcggc ggcgagcatc
    12361 tccccgagct gctcggaggc ggggccgccg gcggcgaggg cggccacgac cggcagggac
    12421 ttcttgcgct gacgcagatc gctccaggtc tgcttgccgg tggcctccgg gtctccccag
    12481 atgccgagga ggtcgtcgac ggcctggaag gccaggccga ggtggtggcc gtaacgctcc
    12541 agggtgtcgg cggtgcgcgc gtccgcgccg cccagcacgg cgccgatcga gctggcgcag
    12601 gccagcaggg cgccggtctt gttgccctcc atctccaggc actcctcgac gctgacgcgg
    12661 tcgcggtgct cgtaggacat gtcctgggcc tggccgtcga tcagggcgcg ggaggcggtg
    12721 gtcagccgcc gggcggcccg gcccgcctcg accgtgccga gttcgaggag gacctcgcct
    12781 gcgagggcga acagggcgtc gccgaccagg atggcctggg cggggccgtg caccttccag
    12841 acggtgtcgc ggtgacggcg ctgctcgtcg ccgtccatca ggtcgtcgtg caggagcgag
    12901 aagttgtgga ccagttcgac ggcgaccgcc ccgggcacgc ccacctcggg cgcggctccg
    12961 gtgacctggg cggagagcac cgcgagcgcg ggacgtacgg ccttgccgcc gtccccgtcg
    13021 gtcgggttgc cctgggcgtc gatccagccg aagtggtagg cggcgaccgt gtccatggga
    13081 gacaccaggc ggtcgacggc cgcgcgcagc accggtgtgg ccagggtccg gccgcgctcc
    13141 agcagcgcgg tcacgtccac cgcggtcctc cgagcggcct tctcggccgg gggcacagtg
    13201 ggcacagttt ctcctcttgt cgcgttaccg gagggggtgc gggggtgtgc cgagccgtgc
    13261 tgatcggtca tcaggcggcc tcctcgacgg cgaagaggcg gcgggggcgg ggccggccga
    13321 gggcgccgag ggcggcgtcc gccgcactga cgccgctgcg gaccgcactc tccatggtcg
    13381 cgggccaccc tgtggcggtc cacgctccgg ccaggtacag gccggatgcc ttggtgcggg
    13441 cgccgggcct gagccgtccg acgccggggg tgggagcgaa ggtggccgtg cgctcccggg
    13501 tcacgaagaa gtcccgcacc gtggcgccgc gggcggccgg cagcagccgc tccagttcgg
    13561 gcaggtagcg ctcgcgcagg gcggcgacgg gtgcgtcgat gtcctcgtgc gcggcggact
    13621 gcgagacggc gaggtactgt cccgcccgtc gcccgccacg gccctcgtca ggcccttcgg
    13681 ggcggcctgt cgacagcccg gaggcgtcgg tgcggtcgaa cacccactgc acgggggtgc
    13741 ccagcgcggt gaggaagggg acgtcgagca ccttgcggtc gtagacgacg tgcaggttca
    13801 ggatcggcgc cgtcccgatg tccagcagcc gctcgggggc gtcgagcgcc ccgtccggca
    13861 gcaggtcgta cgtctcgcgc tgtggtacgg cgagcacgac ggcgtccgcg cggagcgtct
    13921 cgccgggcac ctgaacggtc caactgccgt tgtcctcggc ggagacggag gtgacacggg
    13981 tacggatctc ggtgcgcacg cccgcggagt cgagggcctt gcgggccagc cggtcgtgca
    14041 gttcgcccag cgggacatgg gcccagccga tgtcggcggc gcccgggtcg gacagcaggc
    14101 cggtcttgaa caccatcgcg gcgagtgcca gggaggtgtc gcccgcgacc gcgttgaggg
    14161 tggcgacgcc gaccaggtcc cacagggcct cgacggcacg cgccgactga ccgtgcgcgg
    14221 tcagccagct gccgaagtcc tgcgcgtcca gggccggatc ggcgagatcg agtcccttga
    14281 gcgcgagcgc ggcccggccg accctggcgc ggtcggcgag cgagaggtgc ggatacgtgg
    14341 cgaggctgcg ccccaggtgg agggggaccg gcagctcgtc gcgccgcagt ctgccgagcc
    14401 gtcgtccctc gggcctggcg aggtcgacga cgggcacgtc gaggcggttc tggatcggtg
    14461 ccagcgccgt gccctcgatg cggtcgagga accagcggta ggcggtgcag cagcgcaggt
    14521 acacatgctg gccgttgtcg acggtgagtc cgtcgcgctg gaaggagaag gccagtccgc
    14581 cgagccgggg ccggctctcg agcagggtga cgcgcacgcc cgcgtcggcg agcgcgagcg
    14641 cggcggtgat gccggcgagc ccgccgccga tcactacggc gtcccgcccg gaggtttccg
    14701 ggatgtcgga gcgcggctcg tcgctcatcg tgcaccctct cctgtgcgcc caccgtgacg
    14761 gtcgaactcc gcgcggcagg ccgtcgcagt cagggacgcc gcgccgctgc ggagggttgc
    14821 gtgccgcttt cctccggcgg catcgccctg gtccacgtcg ttgtcacccc gtgggtccat
    14881 cagatctgcc tcctgccgga catccgggac acatggcggg tgtccagacc ggagaggccg
    14941 cggacggcga cgtaggcctt ctcccggccg ggcagcgaga cccggccgcg caggacggcc
    15001 tcggggtcgc gttcgatgcg gtcgaggagg cggcggtaga tgccggccat ggcggccacg
    15061 caggcgccgc tacgccggtc gagcagggga agcagccggt agccctcggc gaacagggcg
    15121 cgggcgcgtc gcacctcgaa gtgcacgagg cccgcgaagt cggagccctc cggcggcgtc
    15181 ggcccgtcga acccggccga gcagccgaac ttggcgaggt cgtcggcggg cagataggtg
    15241 cgcccgccga gggcgtcctc gcggacgtcc ctgaggatgt tggtcagttg gagggcgagg
    15301 ccgagggtgt cggcgtactc cggcgcccgg tcggcgccgc gcgcccccgc ttccgtgccg
    15361 aacacgccga gggagagccg cccgatggcg cccgccacgc agcggcagta cgtcctcagg
    15421 tcgtcccagg tctcgtaggt ctcgccgcgg acgtccatca ggacgccgtc gatcagctcg
    15481 tccaggccgc ccagcgggat cgggaagacc cgcgcggcgt gcgcgagggc gaccgcgacg
    15541 gggtcggtgt cgtcctcctc gacctcgccc gcgcggaccc gggtgagcag cgcccgcgtg
    15601 tcctggagcc gggcgctctt gacctcgccg cccagcgcgc cgtcgccgat gtcgtcgacg
    15661 cggcgcgaga acgcgtacag cgccgacatc gcacgccgct tcgcggtggg cagcagccgg
    15721 atgccgtagg cgaagttgcg cgcctgttgg ccggtgacgg tctcgcagta gccgtaggcg
    15781 gcgagtaccg gcgcggacac gggtggcggt gactccacgg tccggatcac ccctctcctc
    15841 gcagggtcac gcccacctcg cgcagcagcc ggagcttgcc gggcttgggc gggccgggaa
    15901 gaacgtcgtg ctgggcggcg gcgatcgcgt ggagcgccgc ccttcctccc gccacgaagc
    15961 ccgcgagcag cagcctcagc ctgccgtgga cgctatccac gaggggggcg ccctcgttca
    16021 ggaggtcgcg ggcgcgctgg gcttcgaagg cgaccagggc gcgcaccgac gcgcccgcgg
    16081 tgaccgctgc gagatccgcc tcctggacgt gaaaacgctt catgtccgcg gcgggaaggt
    16141 agacacggtc gcggccgagg tcctcggcca cgtcctggag gtgctcgacg atctggagcg
    16201 cggtgcagat cgcgtcggag aggcggacgc gctcgggggt cgtggtgccg gtgacggcga
    16261 ggaccaggcg gcccacgggg ttggcggaca gctcgcagta ggccagcagg tcgtcgtagg
    16321 tctcgtaccg ggtgacgagc tggtcctggc ggttggcggc gatcaggccg aggaagggct
    16381 cgggggtgag cgagcggcgg cgcacggtgg gcctcaggcg acgcagcagg gggtggcggg
    16441 gcgtgccgtc gaagacgcgc cgcaggtcgc ctcgaaggcg tcgaggagga ccaggcggtc
    16501 ctcggcctcg tcggccggca cgcccagcag gcgggcgtcg gcgccgccgg gtgccaggtc
    16561 gccgtcaccg atgtcgtcga cgaggcgggc gaagccgtac acggccacca ggtcctcgcg
    16621 ccagtcccgg ggcaggaaga agggggcgac ggggaagttc tcgtcggcgg ccttggcgag
    16681 ggtgccgcgc tccgcgtccg cggtgcccgg cgccgtcatc gtcggctgcc cggggcaggg
    16741 acggcgcatg ctgcgttgag ctggggagtt tccgtagcca ttgccgtcac atctcccgtt
    16801 ctacaccgac aacccgacac ccactatttc ggacacgccg cccggccgcc cgcgtggcag
    16861 ccgggcccgg aggtgtcgcg cattatcgcc ccacttgacg cgtttcggga cccgccacag
    16921 cttacgttgt acaacgcggc gcggtacgcg cgggtgtccc gcagatcaca acaacacacc
    16981 gatcggcgtc aagcttccta cggcgggaag gagttgacgc ctcctttgca gacgcggggc
    17041 cccgtcggac agttccggcg gggccccgac ggcgccgggt cacttcccgg agaacttctc
    17101 gtactcccgc aggacctctt cggtcggtcc gtccatgcgc agttcaccgc gctccagcca
    17161 cagcacgcgg tcgcaggtgt cccggatcga cttgttgctg tggctgacca ggaacaccgt
    17221 cccggcctgc ccgcgcagct cccggatgcg ttcctcggag cgcttgcgga acttcgcgtc
    17281 gccggtggcc agcgcctcgt cgatcatcag gacgtcgtgg tccttggcgg cggcgatgga
    17341 gaaccgcaga cgggcctgca tgccggagga gtaggtgcgc atgggaagag tgacgaagtc
    17401 gcccttctcg ttgatgccgg agaagtcgac gatctcctgg tagcgctcct tgatctgctc
    17461 ccgggacatg cccatggcga gcccgccgag cacgatgttg cgctcgccgg tcaggtcgtt
    17521 catcagggcg gcgttcacgc cgagcagcga gggctggccg tcggtgtaga ccttgccgct
    17581 ctcgggcggc agcaggccgg cgatggcgcg cagcagggtg gacttgccgg agccgttgga
    17641 gccgatcagg ccgatggcct cgccgcggtg ggcgacgaag gagacaccgc gcaccgcgtg
    17701 caccttgcgc acgccccgct cctcgccgcc gcgtctgacg atgcggctga gggccgcggt
    17761 ggcgctgccc ttccccgtcc gggcgccgtt gacgcggtag acgatgtgca cgtcctcggc
    17821 gatgacggtg gggacccggg tgcccggcgc ctgctcagcc acggccgtac ctctcctccg
    17881 cctgccagaa gtagacgaag ccgccgatcg cgaacagcgc ggcccagccg ccggcgacgg
    17941 cccacacgtg ctggggcagg ttctcggagc cgtactcgtc gatgagggcg aagcgcacca
    18001 ggtccatgta gatggcggcc gggttccact gcaggacgtt cgccatccac tgcggcttgt
    18061 cggcgaggaa gacggggatg gagaacatga cgccggaggc gtacatccag gtccgcatca
    18121 cgaacggcat cagctgcgcc aggtccgggg tcttggcgcc ggcccgcgcg aacaccagtg
    18181 ccagaccggt gttgaagcag aactggagca ccagcgccgg gacgatcagg atccaggagg
    18241 cgtccgggta gctgccgaaa ccgatcacca ccaggaacag cacgatcatc gagtacagca
    18301 gctgctggag ctgctggagc gcgaaggaga tcggcagcgc ggcccgcggg aagtgcaggg
    18361 cgcggaccag gccgaggttg ccggagatcg cgcggacgcc gctcatcacc gaggactggg
    18421 tgaaggtgaa gacgaacaca cccgtgacga ggaacgggat gtacacctcc ttctccatgc
    18481 cgcggctggc gttgaggatc acgccgaaga tcatgaagta cacggcggcg ttcagcagcg
    18541 gtgtggccac ctgccacagc tgccccagct tcgcctggct gtactgggcg gtcagcttcg
    18601 cctgggagaa ggccaggatg aagtgacggc gtccccagag ccggccgacg tactcccgca
    18661 gcgggggccg ggcaccactc acggccaacc cgtacttggc ggccagctgc gccgccgtga
    18721 ggccctcgtc gggcgacggc ggcgcactca ccgcgactgc gccgtcatgc gttgtctcac
    18781 tcaccagtag gaaactttcg tcttcgggat gcgcggcctg aaccgggccg gcacgtgccg
    18841 gggggccgcg gaacggcccg gggccctcgg ggacgagctt gtcagatgac gggaggccgg
    18901 cccagtcggg tcagccgcca caccgtacgc cacttcatgg gcctgcgcgg tccgcacggt
    18961 gtggcccacc cttcccggaa accaccgaac cacgccttca gggccgagcg cgaggggcgg
    19021 cgcagcagag tgagcagcaa ccagaccccg aggtagaccg ggacgagggg cgcggggagg
    19081 ttgcgccggg ccagccagac ccggttgcgg gcgaccatgc ggtggtagac cgcgtgccgc
    19141 gagggcgcgg tcgtcgggtg gtgcagcacc atgtcggacc ggtagttgat catccagccc
    19201 gcgtcgaggg cccgccatgc caggtcggtt tcctcgtggg cgtagaagaa ttcgtccggg
    19261 agaccaccga cctccgcgag gacccgggtg cgcaccgcgt tggcgccgcc gaggaaggtg
    19321 gtgacccggg aggagcgcat cgggtcggcg gcgcgcagcc ggggcacgtg gcggcgctgg
    19381 gtgaccccgg tatcggggtc ggcgatgcgg aagctgatga tgcccagctc ggggtcggcc
    19441 gcgaaggcct cgcggcacag ccgggcggtg tcgtgccggg cgagcagccc gtcgtcgtcg
    19501 aggaacatca atatgtcgac gtcgcggccg ctggggccga aggcctccgt gccgacgttg
    19561 cggccgccgg ggatgcccag gttctcgggc agctcgacgg tgcgcacgtg cggggagaac
    19621 tcggtgacgt ccgggaccgg ggagccgttg ccgacgacga cgacctcgac cgggtcgccg
    19681 tcctgcttgg cgaccgagtc gatcagcgcg cgcagttcct cggggcggtt gcccatggtg
    19741 atgatcaccg cgccgacctt catgggcgcg ctcaccgcag cctgctcgac gcgaggatgg
    19801 acaccaggtg cagcacggtc tggagcagtg cgatgccggc gagtacggcg acgccgagcc
    19861 gggagaagaa gaggtcgccg cgcgtctggt ccacgatcgc caggaccagg atgagcagcg
    19921 aggcctccat cccgaggacc aggcggtgga acttgagcgc ggcggccgcc cggcgggcca
    19981 gcgccatgcc ggaggatcgc ggctcggacg ccgtctcctt gaccggcggc agtccgccct
    20041 ggtggcgggc gacgccgacg aggtcggtct ccgccttgat caggatggcg ccgagcgcgg
    20101 ccagggtgcc gaggaaggcc cacagccagt cgatacggcc ggtgccccac aggtcggcgg
    20161 cgcgcaggcc gaagccgacg agcaccgcgg cgtcggtcag gtaggccccg acccggtcga
    20221 ggtagacgcc gccgagcgag tactgcttct tccagcgggc gatctcgccg tccacgcagt
    20281 ccagcagcag gtacatctgg acgcagacca ggccgagcac ggcgcccgtg atccccggca
    20341 ccagcagggc cggggccgcg agcacgccga agacggtcat caggtacgtg agctggttgg
    20401 gcgtgaccct ggtgttgacc aggtagcggt cgacccgcag ggacacctca cgcatgtaga
    20461 ggcgtcccat ccagtgctca ccgctgcgcc ggtccttcac ccccgcgggg tggacgaccg
    20521 gtctgagttc agctaccgat ggccttgaca tagtcggcgt aggtgtcctt gatctgttcg
    20581 gtcttgaggt cgaggtgttc gaggatcgtg tagcggccgg ggcgggtctg cggggcgaac
    20641 tcgacgacct tgacgaactc gtcggtcgtg aagccgatct cgtcgggcag caccggcagc
    20701 ccgtgccggc gcagcacctc ggccatgtag acggactcct cgtgggctcc gcgcaggtac
    20761 atcgcgaagg ccgcgccgag tccgcactgc tcgccgtggg cggcggcacg cttgggatac
    20821 agcaggtcga aggcgtggtt gatctcgtgg caggcgccgg aggaggggcg ggagtcgccg
    20881 gacaccgaca tcgcgatgcc gctgaggacg agtgcctcgg cgagcacctg gaggaagccg
    20941 gtgtcgccga tgccgcccgg gtgcctgagg accgcctcgc ccgcctgccg ggcgatcgcg
    21001 gcggcgaggc cgtcgatctt ctcgcccttg acgcggtggg ccagctccca gtcggcgatc
    21061 gcggagatgt tggagacggc gtcgccgatg ccggcccgca cgtagcgcac cggtgcctcg
    21121 cggatgacgt ccaggtcgat cacgaccgcg atcgggttcg gcacgccgta ggagccgcgg
    21181 cccgcgtcgt tgtcgagagt ggcgaccggg gagcacaggc cgtcgtgcgc gaggttcgtc
    21241 ggtacggcga cgagcgcgag gcccacccgg gccgcggcga acttggcgca gtcgatgatc
    21301 ttgccgccgc ccaggcccac gaccgcgtcg taatggccgg cctttatgtc accggcgagc
    21361 cgcacggcgt cgtcgagggt gccgccgccg acctcgtacc aggtggcgcc gggcagggag
    21421 ggggagaggc gctcgcgcag ccgggcgccc gagccgccgc tgacggcgat cgcgagcttg
    21481 cccgagtgcg agatgcgctc gtcggcgagg acccccacga ggtcgtcgag ggcacccgga
    21541 cggatgtcga cgacgaccgg cgaggggatc agccgggtca gtactggcac gcgatctccc
    21601 gtccacgggc gagatcgtcg tggttgtcga tctcgaccca gctgacgtcg ccgatcgggg
    21661 ccacgtcgat ccggaagcct cggttcacca gttcctggta gccgtgctcg tagaactgct
    21721 gcgggtcggt ctcccacacg gtcttcagcg cgtcggccag ttcgggggcg gcgtcgccct
    21781 cgatgagggt gacgccgatg tactcgccgg tggcctcggc ggggtccatc agcttggtga
    21841 tcttcgtcat gcccttcgcg gggtcgacga cgaccttcat ctcctcgtcc gcgagggact
    21901 tcacggtgtc gagggcgagg atgatcttcc tgccctcgcc gcgggcggcg agcagggtcc
    21961 tctcgacgga gaccgggtgc acggtgtcgc cgttggcgag gatcacaccg tccttgaggg
    22021 cgtcacgccc gcaccacagg gagtaggcgt tgttccactc ctcggccttg tcgttgtcga
    22081 tgagggtcag cttgaggccg tacttcgcct ccagggccgc cttgcgctcg tacacggctt
    22141 ccttgcggta gccgacgatg accgcgacct cggtcagacc gatctcggcg aagttgccga
    22201 gggtcaggtc cagcaccgtg ggctcgccct ctatgcccgc gggccccacc ggcaccagcg
    22261 ccttgggcag gctgtcggtg taggggcgca gacgccgtcc ggcgccggcc gccagcacga
    22321 ggccgatcat gcgggttctc cttcatcgtg tacggacggg gcgcccgccc ggtgggcggc
    22381 gacccagaag cggatgctct cggcgagcac cacgagggcg acggccacgg cgagcaccgt
    22441 gagcgcgacc gtgaactgcc gggcggtgag caccgcggcc agtacggcca cgagcagcgt
    22501 ccgcccctcc tgtcccccga cagcgcgcac cagccaggcc ggcggcgctc cggcgttgcc
    22561 gcggatgcgg tacaccgtgt cgtagtgatg gtaggcgaca gcggcaacca gcccgaaagc
    22621 cgccggtagc gctccgttca catccgcctt cgccgcgagg atcagcaccg tgccgtactc
    22681 ggcggcgcgg aacaccggcg ggacgagcca gtcgagggcg cccttgaggg ggcgggcgac
    22741 ggcttcggcg gacagcagga cataggcacc ggccatcagc acgacccacc agctcggtcc
    22801 ccacagccag gcgccgagcg tgacgagcac ggcaccggcg gctgcgctga gggtcgccgt
    22861 cggccgcgcc cccgccgggc aggaaccgca ccagcaggcc ggccgtcggc ccgctgtccg
    22921 cgaggtccgc cagggcctgt gcggcccggt ccgtgcgccg cgccttgcgg gtgagggagc
    22981 gcaggaggcg gcccgccgtg gtgtacgtcg cggcgaaggc gcagccgacg agcaggacgt
    23041 agaaggtgat gcggggggtg gtggccgcgg tgaggacggc gatcatggcc catcgttcgc
    23101 cgatgggcag gactatcatc cggcgcgccc agaccgtcca gccgacgctg tccagcttgc
    23161 cggagagggc cgcggtgggg ctggtgttcg cggtggcggc ggtgctgtcg acgttcgcct
    23221 cgttgaagga gaagtccacg acgtgccggc aggtctggag gaccatcgcg ccgagggcca
    23281 gggcccagac gtcgtcgccg ccgcgggccg ctccgagggc gagtccggcg tagtaggcgt
    23341 actccttggc ccggtcgaag gtggcgtcca gccaggctcc gagggtggag tactggaggg
    23401 agtagcgggc gagctggccg tcggtgcagt ccagcacgaa ggagaagagg agcagcagtc
    23461 cggcggcgac gtatccgccg cgggtgccgg tggccgcgca gcccgccgcg atcagcgcgg
    23521 tgatcagcga ggcggtggtg acctggttgg gggtgagccc acggcgggcg caccagcggg
    23581 cgaggtagcg cgagtagggg ctgatgcaga acgtggtgaa gaagccgtcg cgggccttca
    23641 ccgccgactt caggcgtacg gtctcgtcgt cgacggcgct gacggcctgc cgtgcctcgt
    23701 tgcgggcctg cgggtcggcc gggacggcgg cgaccaggct gcccagctcg ggccggtgca
    23761 cctcgccgcc gtcggcgtcg agggcggtga cgatgcggtc ggcgaggctg tccacggcga
    23821 ggacggtgcc gccgttcgcc gagttctcgc gggccagggc gcgggtcagg gcctgccggc
    23881 cggccggctg cgcggtgacg gcgccgggga tcgcggcgag cgggaagcgg gggtcggtga
    23941 ggcctaggcg cagcgcgtgg cgatggccca cgaagcgggt gtcgacgacg gcgacccgct
    24001 ggtcacccgg gacggccgcg aggagcgtct ccgcgtcggc ggcatcggtg gcggtccgga
    24061 cgtcgaagcc gagggaccgc aggtctgcct cgatcgacga accggggacc ggctgaccgg
    24121 tgaggatggc ggtcgacaac cgaactcact ccctgggtcc cggcgcgtgc gcgccggtcg
    24181 tctgcatggt gggctctgca tggcgggcgc cccttggcgg caccggtgaa ggcaccgggc
    24241 gcggcattcg gcagaggcta tcggatgccg ggaaggccgt gttcaccggc cgttcaggtc
    24301 cgatccacac ggtccggacc ggccgtcgcc gagatcatca tgtgtgatcg gcggccccgc
    24361 ccacaaaccg cgctccccgg tggcggacat ccgggacatt gcgcacggac ccgggggctc
    24421 ggcatagggt gggcggccat gacgtggctg atcaccggcg gggccggata cataggggca
    24481 catgtggcgc gggccatgac cggcgccggc gagcgcgtcg tcgtcctgga cgacctgtcg
    24541 gccggcgtgc ccggtcggct gcccgcggac gtgccgctcg tggcgggctc ggcgctcgac
    24601 gcggggctgc tgaagcgggt gctggccgag cacgcggtga ccggggtggt gcacctggcg
    24661 gcgcgcaagc aggtcgccga gtcggtggcg cggcccacgc gctactaccg ggagaacgtc
    24721 ggcggtctgg ccaccctgct ggaggcggtc gccgaggccg gtgtccgccg gttcctgttc
    24781 tcctcgtcgg cggccgtgta cggcaacccg gacgtggacc tcatcacgga ggacaccccc
    24841 tgctccccgg tcaacccgta cggcgagacc aagctcgccg gggagtggct ggtgcgggcg
    24901 gcgggcgagg cgcacggcat cgcgacgacg tgcctgcgct acttcaacgt ggccggggcg
    24961 gccgagcccg ccctggccga caccggcgtc ttcaacatcg tcccgatggt cttcgaccgg
    25021 ctcacccgcg acgaggcccc gcggatcttc ggcgacgact acccgacgcc ggacggcacc
    25081 tgtgtacggg actacatcca cgtcgccgac ctggccgagg cgcatctcgc ggcggcccgg
    25141 cggctcaccg cgccggacgt gcgcggcgat ctgacggtga acatcggccg gggcgagggc
    25201 gtctcggtgc gcgagctggt cacgctgatc ggcgaggtca ccggcgaccc ccggcccgcc
    25261 ctggtcgagg gacgacgccc cggggacgcc ccgcgcgcgg tggcctcggc cgcgctggcc
    25321 gcccgggaac tgggctggac cgcctcgcgc gggatgcgcg agatggtcgc gtcggcctgg
    25381 cggggatggc agctgcacca cggcgggtga gccggcgccg ggccgctgac ctgcatttcg
    25441 ttttcgcagg tcagggcaca tgacaacggt gttcagtgcc gcgttgccgg atacccccca
    25501 cccgtagttc actgggaggc cgggcggatc acaggaggct gtttctcatg ggggctgggc
    25561 acgaccacgg ccacacgcac gtgccgacca cgggtacggc cgcggcggcg taccgcggca
    25621 gactgcgcgc cgcgctctcg atcacgctca ccgtcatggt ggtggagatc gtcggcggtg
    25681 tgctcgccga ctccctcgcc ctgatcgcgg acgcggcgca catggcgacc gacgcgctcg
    25741 gcctggggat ggcgctgctc gccatccact tcgcgggccg cccgccgacc gggaaccgca
    25801 ccttcgggta cgcccgcgcc gagatcctgg ccgcgctcgc caactgtctg ctgctgctcg
    25861 gcgtgggcgg gtacgtcgtg tacgaggccg tccagcggtt cttcacgccg gccccgaccg
    25921 agggcgggct gatgatcgtg ttcggtggga tcggcctggc cgccaacatg gtctcgctga
    25981 gcctgctgat gcgcggccag gcggacagca tcaacgtgcg gggcgcgttc ctggaggtgg
    26041 cggcggacgc gctgggctcg gtcgcggtgc tggtctcggc ggtggtgatc ctgacgaccg
    26101 gctggcaggc cgccgacccg gtcgcctcgc tcgtcatcgg cctgatgatc gtgccccgga
    26161 cggtgaagct gctgcgcgag acgctggacg tgctgctgga ggcggctccg aagggcgtcg
    26221 acatggcgga ggtgcgcacc cacatgctcg ccctggacgg cgtggaggac gtgcacgacc
    26281 tgcacgcctg gacgatcacc tccgggatgc cggtgctgtc ggcgcacgtg gtggtgcgct
    26341 ccgacgtgct ggacgcgatc ggccacgaga agatgctgca cgagctccag ggctgtctgg
    26401 gcgatcactt cgacgtggcg cactgcacct tccagctgga gccgagcggg cacgcgcagc
    26461 acgaggcgcg gctctgccac tgaccggccg ggcggcaccg ggttcgcaca tccgttccgg
    26521 acggttccgg gcgcgcggcg ccgggcaaga tcacccaccg ggccccgttt ccggagactg
    26581 ggcggcggcc gccgtggtcg cgccgggcgg cgggacatgc gggcgtgcgc gcggaagtgc
    26641 cgggagtgcc gtgcgcgtac ggcagactgg gggcgcgagg accgatgtta aggatgggta
    26701 tgccgatcac acctgccac
//
