LOCUS       NZ_CP017968            13169 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Paenibacillus polymyxa strain YC0573 chromosome, complete genome.
ACCESSION   NZ_CP017968
VERSION     NZ_CP017968.3
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 6126117)
  AUTHORS   Liu,H., Hou,Q., Liu,K., Wang,C., Ding,Y. and Du,B.
  TITLE     Complete Genome Sequence of Paenibacillus polymyxa YC0573, a Plant
            Growth Promoting Rhizobacterium Isolated from Rhizosphere of Tobacco
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6126117)
  AUTHORS   Liu,H., Hou,Q., Liu,K., Wang,C., Ding,Y. and Du,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2018) Department of Microbiology, Shandong
            Agricultural University, No. 61 Daizong Street, Taian, Shandong
            271018, China
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 6126117)
  AUTHORS   Liu,H., Hou,Q., Liu,K., Wang,C., Ding,Y. and Du,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-NOV-2016) Department of Microbiology, Shandong
            Agricultural University, No. 61 Daizong Street, Taian, Shandong
            271018, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: canu v. 1.3
            Genome Coverage                   :: 140.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 04:02:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,505
            CDSs (total)                      :: 5,362
            Genes (coding)                    :: 5,219
            CDSs (with protein)               :: 5,219
            Genes (RNA)                       :: 143
            rRNAs                             :: 13, 12, 12 (5S, 16S, 23S)
            complete rRNAs                    :: 13, 12, 12 (5S, 16S, 23S)
            tRNAs                             :: 102
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 98 of 143
            Pseudo Genes (incomplete)         :: 53 of 143
            Pseudo Genes (internal stop)      :: 19 of 143
            Pseudo Genes (multiple problems)  :: 23 of 143
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:01:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5958164
            Orig. end                         :: 5971333
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017968.3.
            On Feb 23, 2018 this sequence version replaced NZ_CP017968.2.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..13169
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="21"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     cand_cluster    1..13169
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13169
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8169](-)"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..8169)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     misc_feature    121..134
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.6"
                     /tool="antismash"
     gene            232..810
                     /locus_tag="PPYC2_RS26440"
                     /old_locus_tag="PPYC2_00820"
     CDS             232..810
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014278856.1"
                     /locus_tag="PPYC2_RS26440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_00820"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_028540896.1"
                     /transl_table=11
                     /translation="MEKSSDVLTKEQILIATEDTLRRFGVAKTSVTDVAKVLGVSHGTI
                     YRHFKSKAELLEGVTEKWLNEKIIGPLTEVCQNSFILGTPHLKRYIQTLVELKQHYARD
                     DEEMFEMYTRVTEQAADLIDLHITHIVDQLADIIARGDITSDQPAQLARTLFYATARFH
                     HPAHAYEWKSPVINQEFSDVWMLLEKGIT"
     gene            842..1582
                     /locus_tag="PPYC2_RS26445"
                     /old_locus_tag="PPYC2_00815"
     CDS             842..1582
                     /NRPS_PKS="Domain: PKS_KR (7-120). E-value: 2.1e-12. Score:
                     39.2. Matches aSDomain:
                     nrpspksdomains_PPYC2_RS26445_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426073.1"
                     /locus_tag="PPYC2_RS26445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_00815"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_053326433.1"
                     /sec_met_domain="adh_short (E-value: 9.1e-34, bitscore:
                     115.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 4.6e-38, bitscore:
                     129.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHLDGKTAIITGSSRGIGRAIAEQLADLGANVVINYASSPDKAQ
                     EVVKSILQKGGKAIALHADLGKMSDIEALFTNTIAEFGKVDILVNNAGLMITQPLAEVN
                     EADFDKQFALNVKGTFFACQQAMKYMENYGRIVNLSTSVIGQMFPAYSVYAGTKGAVEQ
                     FTRQLAKEFGSKQITINAVAPGPVNTELFQAGKTEQQIEGMKKMNAMGRLGEPEDIADV
                     IEFLVSAKSQWVTGQTIRVNGGFI"
     aSDomain        863..1201
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PPYC2_RS26445_PKS_KR.1"
                     /evalue="2.10E-12"
                     /label="PPYC2_RS26445_PKS_KR.1"
                     /locus_tag="PPYC2_RS26445"
                     /protein_end="120"
                     /protein_start="7"
                     /score="39.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TAIITGSSRGIGRAIAEQLADLGANVVINYASSPDKAQEVVKSIL
                     QKGGKAIALHADLGKMSDIEALFTNTIAEFGKVDILVNNAGLMITQPLAEVNEADFDKQ
                     FALNVKGTF"
     CDS_motif       869..934
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PPYC2_RS26445_0001"
                     /evalue="3.60E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="PPYC2_RS26445"
                     /protein_end="31"
                     /protein_start="9"
                     /score="16.4"
                     /tool="antismash"
                     /translation="IITGSSRGIGRAIAEQLADLGA"
     gene            1619..2155
                     /locus_tag="PPYC2_RS26450"
                     /old_locus_tag="PPYC2_00810"
     CDS             1619..2155
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373777.1"
                     /locus_tag="PPYC2_RS26450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_00810"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_053326434.1"
                     /transl_table=11
                     /translation="MILNKGETLFRQGESGPLYHLKSGLLKIVRVHEDGSQILVNVIVP
                     DEIIPHHSLISPNPYYGTAVALVTSEVEVLSQKEWYQALEQDPAQCRAIALQLQDKLRM
                     MQQRIDQLTEVSPAEKLRKLQRWFHSYIAPATLTDVLTQEEIGQFIGLRRETINRLLRA
                     SSVPSAKDDDDNASQ"
     gene            complement(2088..2609)
                     /locus_tag="PPYC2_RS26455"
                     /old_locus_tag="PPYC2_00805"
     CDS             complement(2088..2609)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312652.1"
                     /locus_tag="PPYC2_RS26455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_00805"
                     /product="DinB family protein"
                     /protein_id="WP_023991015.1"
                     /transl_table=11
                     /translation="MNTTETLQRFEETAQHYLLELDSFSLEELQYTPQEGQWSLGQMYL
                     HLVNSALYMHLKNIDLCLQPNGETGVKTEAGTAIFNLGSFPPMRIQVPPSPQYTPQQPT
                     SKEEIVEGLNVVIRKMREIEPTVGKSTTLFTVSHPSFGALNAGEWFELIEMHYRHHLLQ
                     KERLKHAIAD"
     gene            complement(2677..3620)
                     /locus_tag="PPYC2_RS26460"
                     /old_locus_tag="PPYC2_00800"
                     /pseudo=""
     CDS             complement(2677..3620)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426071.1"
                     /locus_tag="PPYC2_RS26460"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_00800"
                     /product="YafY family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNKTDRLLAILLELQRKDILRAEDLAAIFETSVRTIYRDIQALSE
                     SGVPIVGAPGIGYSLMEGYFLPP"
     gene            complement(3731..4087)
                     /locus_tag="PPYC2_RS26465"
                     /old_locus_tag="PPYC2_00795"
     CDS             complement(3731..4087)
                     /GO_function="GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822573.1"
                     /locus_tag="PPYC2_RS26465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_00795"
                     /product="nucleotide excision repair endonuclease"
                     /protein_id="WP_023991017.1"
                     /transl_table=11
                     /translation="MINITIPTPDITITKQVNPELSHIYGFTDFHLIPRDKAGIFMFYN
                     TQEELLFVGKARKLRQRIKKHFEDTVSPIKDKRNEVAIIEVCIVEDAVEREIYETYIIN
                     SQKAKYNVEKVFFK"
     misc_feature    4114..4129
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.06"
                     /tool="antismash"
     gene            complement(4244..4984)
                     /locus_tag="PPYC2_RS26470"
                     /old_locus_tag="PPYC2_00790"
     CDS             complement(4244..4984)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014278862.1"
                     /locus_tag="PPYC2_RS26470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_00790"
                     /product="YheC/YheD family protein"
                     /protein_id="WP_053326436.1"
                     /transl_table=11
                     /translation="MASGAKDKWYKYLLLRRYASLRSYVPETRLLDRHNFSKLLSKYVH
                     VIVKPVWGSRGRGIFQVSWLGNHKYIVHYENKRVLVRGRTNTYHYIRRKIGNASYMVQR
                     RITRPTINKRPFDMRVIIQRRTGSPVWVVTGKVIKVAGKGYIVSNNTRSKGTLLSFKSG
                     IKQSSVRHLSASALESRINRVSIRSAKRLSNFFPGHRMYGLDIGIDRKGRIGIIEANLY
                     PARSHFRKLKDKTMYYRITDYKNG"
     gene            complement(5001..6113)
                     /locus_tag="PPYC2_RS26475"
                     /old_locus_tag="PPYC2_00785"
     CDS             complement(5001..6113)
                     /EC_number="2.6.1.37"
                     /GO_function="GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA]"
                     /GO_process="GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_5 (33-305). E-value: 2.3e-32.
                     Score: 104.2. Matches aSDomain:
                     nrpspksdomains_PPYC2_RS26475_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014278863.1"
                     /locus_tag="PPYC2_RS26475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_00785"
                     /product="2-aminoethylphosphonate aminotransferase"
                     /protein_id="WP_053326437.1"
                     /sec_met_domain="Aminotran_5 (E-value: 9.6e-27, bitscore:
                     92.2, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.7e-06, bitscore:
                     25.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSVVKKNILLTPGPATTTESVKCSQVVPDICPREAEFGQIMEYI
                     STELTRLVADPDDYATVLFGGSGTAAVESIISSVPNHDAVIIVSNGAYGKRMCEIAKVY
                     GVDYFEFKSSPDDAIDLAELERYIQSSERTVSHLAVVHHETTTGLLNKVKDIGELCKRY
                     QIDMIVDAMSSFAAVPIQLKEMNIAYLAASSNKNLQGMAGVSFVIAEKSKLENLKGQKP
                     RSYYLNLYAQYNYFVEHGQMRFTPPVQTLYALRQAIEELKQEGVDKRYERYATSWKTLI
                     NGLARLGLTYIIPEEHHSKIITSILEPHCAGYDFQSMHDYFYSKGMMIYPGKLEKLNTF
                     RIANIGDITYKEMELFLELLEGYLSSIKCG"
     aSDomain        complement(5199..6014)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PPYC2_RS26475_Aminotran_5.1"
                     /evalue="2.30E-32"
                     /label="PPYC2_RS26475_Aminotran_5.1"
                     /locus_tag="PPYC2_RS26475"
                     /protein_end="305"
                     /protein_start="33"
                     /score="104.2"
                     /tool="antismash"
                     /translation="REAEFGQIMEYISTELTRLVADPDDYATVLFGGSGTAAVESIISS
                     VPNHDAVIIVSNGAYGKRMCEIAKVYGVDYFEFKSSPDDAIDLAELERYIQSSERTVSH
                     LAVVHHETTTGLLNKVKDIGELCKRYQIDMIVDAMSSFAAVPIQLKEMNIAYLAASSNK
                     NLQGMAGVSFVIAEKSKLENLKGQKPRSYYLNLYAQYNYFVEHGQMRFTPPVQTLYALR
                     QAIEELKQEGVDKRYERYATSWKTLINGLARLGLTYIIPEEHHSKIITSI"
     gene            complement(6110..7270)
                     /gene="aepY"
                     /locus_tag="PPYC2_RS26480"
                     /old_locus_tag="PPYC2_00780"
     CDS             complement(6110..7270)
                     /EC_number="4.1.1.82"
                     /GO_function="GO:0033980 - phosphonopyruvate decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aepY"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312657.1"
                     /locus_tag="PPYC2_RS26480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_00780"
                     /product="phosphonopyruvate decarboxylase"
                     /protein_id="WP_053326438.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 3.8e-09, bitscore:
                     34.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.8e-15, bitscore:
                     54.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTKLLGEELKKLGFTFFSGVPCSFLKSLINYAINECDYVAAANE
                     GDAVAIASGAYIGGKKSVVLMQNSGLTNAVSPLTSLTYPFRIPLLGFVSLRGEPGIPDE
                     PQHELMGQITTQMLDLMDVEWQYLSKDLEEVKNQLIQANEQIARNRPFFFVVKKGTFDK
                     EPLKKQQTSIHLNQIRQHGRANHQMPTRYDALCAINSMKDSHTVQLATTGKTGRELYEI
                     EDADNNLYMVGSMGCIGSFGLGLALSQPSKNIVVIDGDGSLLMRMGSLATNGYYHTANM
                     IHIMLDNNAHESTGGQSTVSHNIDFIDIAASCGYTKSILVHSLEELKVFLQEWKMNREL
                     TFLCLKISKDSKDQLARPHMKPLEVKERLQRFIHNDPLKGKEVGGS"
     gene            complement(7270..8169)
                     /gene="aepX"
                     /locus_tag="PPYC2_RS26485"
                     /old_locus_tag="PPYC2_00775"
     CDS             complement(7270..8169)
                     /EC_number="5.4.2.9"
                     /GO_function="GO:0050188 - phosphoenolpyruvate mutase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="aepX"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) phosphonates-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014278865.1"
                     /locus_tag="PPYC2_RS26485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_00775"
                     /product="phosphoenolpyruvate mutase"
                     /protein_id="WP_053326439.1"
                     /sec_met_domain="phosphonates-like (E-value: 3.8e-137,
                     bitscore: 454.1, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.5e-128, bitscore:
                     426.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2e-67, bitscore:
                     225.5, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTKQLRDLVNSQTPEFIMEAHNGLSAKIVEEAGFKGIWASGLS
                     ISAAMGVRDNNEASWTQVLDVLEFMSDATSIPILLDGDTGYGNFNNARRLVKKLEQRHI
                     AGVCIEDKRFPKTNSFINGQEQTLADIEEFSGKIKAMKDTQTDTDFTVVARVEAFITGS
                     GLKVALQRAEAYRKAGADAVFIHSKRSDAAEIEAFMKEWAGRLPVVIVPTKYYTTPTVR
                     FQEMGISLVIWANHNLRASIQAMKQLSGRIYRDESLVHVEKEVATLEEVFRLQGVEELQ
                     AAEKKYLPSSEPDSGERV"
     gene            complement(8212..8940)
                     /locus_tag="PPYC2_RS26490"
                     /old_locus_tag="PPYC2_00770"
     CDS             complement(8212..8940)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014278866.1"
                     /locus_tag="PPYC2_RS26490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_00770"
                     /product="YheC/YheD family protein"
                     /protein_id="WP_053326440.1"
                     /transl_table=11
                     /translation="MPIGKMKKHKEMLQHPVLRSHLPETHWFTDSRTSRMLNTYSSVFI
                     KPNHGSGGSGIIRVKRLKKGYEVRSGSSRKFVGSRFVLKAIKSYRKSRHRYLVQKGLRL
                     AKYHGSIFDTRIYLQKPRGKWVISGVAARVAAPHKYVTNYLKGGHAVSLHRVLFSLFKH
                     NRAKADAYFRRISKLSVIIAKKINERHPVRELGVDIAIDKKGHIWIIEANSHPGHMLFT
                     QFPDPTMINTIMRNKSLIRK"
     misc_feature    8968..8986
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 23.39"
                     /tool="antismash"
     misc_feature    complement(8983..8996)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.88"
                     /tool="antismash"
     gene            9236..10435
                     /locus_tag="PPYC2_RS26495"
                     /old_locus_tag="PPYC2_00765"
     CDS             9236..10435
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010346910.1"
                     /locus_tag="PPYC2_RS26495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_00765"
                     /product="glycosyl hydrolase family 28-related protein"
                     /protein_id="WP_053326441.1"
                     /transl_table=11
                     /translation="MSNIFNRKVRFSFLLVAIIAFVIQNSTGDIHVARAADNVINAKDF
                     GVKANSNSSQSKEIQNALKYFYDRGMEGTVYFPKGTYLVDESIRLYAGVSLNGDGMGKT
                     IFKKTGSKSQYVVGDPILRNNSDRLDVKLSNLTIDADRANREARGESQVGGIIMEMAVS
                     HFTLDHVEICDTTIGALLRRTRDSEITNSRFDRNNGHAIATGHESFPAGEFRNVKITNN
                     QITNSGGGSGINLSRATYTTVTGNQIINKTHQSDGYAGIRIPNNGANNTVNNNVIENYP
                     RGIFVLTGATGNNVYGNTVKNASLQGLLVQSDGNTFTDNEFIQTNSSLTPEAVIRLADA
                     NNNKVIGNEMTTYSGFSNIGIRVTDSNSNEIKDNITDTRGKSVSIEGGRNNVNTGNRNR
                     "
     gene            10554..11177
                     /locus_tag="PPYC2_RS26500"
                     /old_locus_tag="PPYC2_00760"
     CDS             10554..11177
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426070.1"
                     /locus_tag="PPYC2_RS26500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_00760"
                     /product="GPR1/FUN34/YaaH family transporter"
                     /protein_id="WP_053326442.1"
                     /transl_table=11
                     /translation="MQNESHSNVKIITADPSAIGLFGLAIVTLVASSQKLGLTEGLSFI
                     IPWAIFLGAFAQLFASIQDAKHNNTFGMTAFGAYAFFWLAVASSWMIKMGVFGPELASA
                     VDGKQLGFAFAGYLIFTLFMTIGAMETHKVLFFIFVLIDFLFLGLSFDAFGVAPEIFHT
                     IAAYAEMGIGLLSLYGTGAAVLNAHFGRTFLPVGRPFGIFKPRP"
     misc_feature    complement(11262..11271)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            11353..12867
                     /locus_tag="PPYC2_RS26505"
                     /old_locus_tag="PPYC2_00755"
                     /pseudo=""
     CDS             11353..12867
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006926165.1"
                     /locus_tag="PPYC2_RS26505"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="PPYC2_00755"
                     /product="FAD-dependent oxidoreductase"
                     /pseudo=""
                     /sec_met_domain="DAO (E-value: 6.6e-14, bitscore: 50.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQDESRTTFPQFPESYWLASTTDIPNFPKLSEDIQVDVAIVGAG
                     ITGITTAYLLSKKGLNIAVVDTGRILHGTTDHTTAKITAQHDLIYSEFLSHFGKEKPGF
                     ITKRTTTLFNLSSKR"
ORIGIN
        1 tctaaattct tggtcgatcg cgatggccat gtaaaaggaa ggtttgaagt aacaaccgag
       61 ccctgtgcca ttgatcctgt catcgaatcg ctattgtaat ttttccgttc acttctttgg
      121 attctttaaa aaaagagtat caaatgacaa aaatgaatat ttgtcatttg atactctttg
      181 tgttatcctg acttcaagga ggtgactcac acggcacttg accgtgtccc tatggaaaaa
      241 tcctcagatg tgctaaccaa ggaacagatt ctcatcgcta cagaagacac ccttagacgt
      301 tttggtgtag ccaaaacttc cgtgaccgat gttgccaaag tactgggagt aagtcatggc
      361 accatttacc gacactttaa aagtaaggcc gagcttcttg aaggcgtgac cgaaaaatgg
      421 ctgaatgaaa agattattgg cccgttaacg gaggtctgtc agaattcatt tatactggga
      481 acgccacatt taaaacgata tatacagacc ttggtcgaac ttaagcagca ttatgcccgc
      541 gatgacgagg aaatgtttga gatgtatacg agggtcaccg agcaagccgc tgatttaatc
      601 gacctgcata tcacacacat tgtggatcag ctcgctgata tcattgcacg cggggacatc
      661 acatcggatc agccagccca actggcgcgt acccttttct atgccacagc ccgttttcat
      721 catcccgctc atgcttacga atggaagagt cccgtgatta atcaggagtt ttcggatgtg
      781 tggatgcttt tagaaaaagg aatcacttaa aatagataaa ggaaagaagg acaaaacaca
      841 tatgaagcat ttggacggaa aaacagcaat tatcaccggg tcctccagag ggattggacg
      901 tgccattgcc gagcaactgg ctgatctagg cgctaatgta gtcatcaatt atgccagcag
      961 tccggacaaa gcccaagaag tcgtgaagag cattcttcaa aaaggcggca aagccatagc
     1021 acttcacgct gatctgggca aaatgagtga tattgaagca ttatttacaa atacgattgc
     1081 tgaattcggt aaagtggata ttctggttaa caacgctggg ctgatgatta cccaacctct
     1141 ggctgaggta aacgaagcag attttgacaa acaattcgca ctcaatgtaa agggcacttt
     1201 ctttgcatgt cagcaagcca tgaaatatat ggagaactac ggaagaatcg tgaacctgtc
     1261 tacatccgtg atcggacaaa tgttcccagc ctatagcgta tatgcaggta ccaagggcgc
     1321 agtggagcaa tttacccgtc agctagccaa agagttcgga agcaagcaaa ttacgatcaa
     1381 cgctgtggct cccggtcctg tgaacaccga gcttttccaa gcaggaaaaa ccgagcagca
     1441 aatcgaaggc atgaaaaaaa tgaatgctat gggtcggctc ggcgaaccgg aagatatcgc
     1501 tgatgtgatt gagttcctgg tcagcgccaa atcacagtgg gttaccgggc aaacgatccg
     1561 cgtcaatggc gggttcatct aaaagctgga atacatggaa tggaggctgt ttacgttcat
     1621 gatattaaac aaaggcgaga ccttatttcg acaaggagaa tccggccctt tatatcactt
     1681 aaagagcggc ttgttaaaaa ttgtccgagt ccatgaagac ggctcgcaaa ttttagttaa
     1741 tgtgattgtg cctgatgaaa ttatcccgca ccactccctg atcagcccca atccttatta
     1801 tggtacagcg gtggcgttag taacctctga ggttgaggtt ttgtcgcaaa aagaatggta
     1861 tcaggcgctg gagcaagatc cggctcaatg tcgggctatc gctttgcagc tacaggacaa
     1921 gttgcgcatg atgcagcaac gaattgacca actcaccgag gtatcacctg ccgagaagct
     1981 gcggaagctc caacgctggt tccactccta catcgcaccc gccacgttaa cggacgtgct
     2041 gacgcaggag gaaatcggcc agtttattgg gctgcgtcgg gagacgatta atcggctatt
     2101 gcgtgcttca agcgttcctt ctgcaaaaga tgatgacgat aatgcatctc aatgagctca
     2161 aaccactctc cagcattcaa cgcaccaaaa ctgggatgag agacggtgaa cagcgttgtt
     2221 gatttcccaa cggtcggctc aatctctctc atcttgcgga tcacgacgtt taatccctcc
     2281 acaatttctt ctttgctagt gggttgttgg ggagtgtact gaggggatgg tggaacttgg
     2341 atacgcattg gcggaaagct ccccagatta aaaatggctg tgcctgcctc cgttttaact
     2401 cctgtctccc cattaggctg tagacaaaga tcaatgttct taagatgcat atacagtgca
     2461 gagttcacca aatgaagata catttgtcca agcgaccatt gaccctcctg aggtgtgtat
     2521 tgcagttcct ccaagctaaa gctgtccaat tcaagaagat agtgttgtgc cgtttcttcg
     2581 aaacgctgca atgtttcagt tgtattcata tattaataat tgcccctctc tatcaaagta
     2641 gctttactat acaaaaatgc tactgacagc attatgtcag tagcatttca acattttttc
     2701 cacttccaca cgtatccgct ccctgagcga ctcaggctcc agcacaacca tatccgcgcc
     2761 ccatccaagt atccattgca gtagttcctc tggctgtctg acgcggaaga gtacatgcag
     2821 tccatctgca cgctcctcta tggcctccat ataaaagttg ttcgcttcct tcaccttatc
     2881 tgcgatatct gaacgtgcta atatgcgaac agttacatga cggtcatcgg tttgcttgta
     2941 atcctgcaaa tgaaaatcga caggcaactc aaacctgtcc tccagcacga taagcttgtc
     3001 catacgcgac agacggaaat ggcgaagctg ctgccgcaat tcgcattgcc caattaacac
     3061 ccaagaacca cggagcagta caagaccata aggagcgacc acgcgcacac tttgacgatt
     3121 cccgtcagcc tctggcattc ttttggagta gccaaactgt actttccgtt tttccaatac
     3181 agcgagacgc agcgtttcca aacaggtttt ctcgctatgg tttgcccctt cacccaccgc
     3241 gagcaatctg atggtcgtac gcacccggga aacttccctg cgaacgctct ccggtaatat
     3301 ggcttcaatc ttcctgcggg aggtttgcgc cttgataccg taatctgtat caaatttttg
     3361 ttcgacaaaa tccgttccga ttagcaacgc cacagcctct tctgcggtaa agctcagggg
     3421 ggcaggaagt acccctccat caaggaatat ccaatgcccg gtgctcctac aatcggtaca
     3481 cccgattcac ttagagcctg aatatcccga tagatggtcc tcacactcgt ttcgaatatg
     3541 gctgccaaat cctcggctcg taaaatatcc ttacgctgca actctagcaa gatcgctagc
     3601 aaacgatctg ttttattcat gccacggccc ctctctggaa ggatctaaaa tgcagaaata
     3661 caaaaaagca ataagggcag tacagtcact gcgacttatt gctctttttt ttcatacgga
     3721 agttacttca ttatttaaaa aacacttttt cgacgttata tttagccttt tgtgaattga
     3781 tgatgtaggt ttcatagatt tctcgctcta cagcatcttc cacaatacaa acctcaataa
     3841 tcgctacttc gttccgcttg tccttgatcg gcgatacggt atcttcaaaa tgctttttga
     3901 ttctttgtct cagctttctt gctttaccaa cgaacagcaa ttcctcttgt gtgttgtaaa
     3961 acataaagat accagcctta tctctaggga tcaggtgaaa gtcggtaaat ccgtaaatat
     4021 ggctgagctc agggttaacc tgtttggtaa ttgtgatatc cggagttgga attgttatat
     4081 taatcactat gtcacttcct cattctatat aggtgtaaat attatcacaa atcccgtggt
     4141 aacaccattt aataatcctt gtcccatgac taaaactccc aacttagaaa ctgtatgaga
     4201 aaaagatgac tctgatgaat acagagccac cttttcattt atgttatcca tttttgtaat
     4261 ccgtaatgcg gtaatacatc gttttatcct tcaacttacg gaaatgggac cttgccggat
     4321 aaagattagc ctcaataatc ccgatacgtc ctttccggtc tattccaatg tccagtccat
     4381 acatacgatg tcccggaaaa aaattactta atctcttcgc ggaacggatg gaaacacgat
     4441 taatacggga ctctagggca ctggcagaca ggtgccgaac agaagattgt tttatgccgg
     4501 atttaaaact gagtaaagtt cccttactcc gtgtattgtt ggaaacaata taacctttgc
     4561 ctgcaacttt gataaccttc cctgtgacta cccatacagg tgagccggtt ctccgttgaa
     4621 tgatgactct catatcaaaa gggcgtttgt tgatggtcgg acgggtaatt ctgcgttgaa
     4681 ccatataact ggcgttcccg atttttcttc taatataatg atacgtattg gttctacccc
     4741 ttactaaaac tcttttattc tcgtaatgta cgatgtactt atggtttcct aaccaggaga
     4801 cctggaagat cccccgtcca cgactccccc acaccggttt cacaataaca tgcacgtact
     4861 tggagagaag tttcgagaaa ttatgcctat ccaggagcct cgtctcgggg acataagacc
     4921 tcagagacgc ataccttctc aataacaaat atttgtacca cttatctttt gctcctgatg
     4981 ccatgggaac tccacctttc tcatccgcat tttatgctac tgagatagcc ttcaagcaat
     5041 tccaaaaata actccatttc cttatacgta atatcaccta tattggcaat ccggaacgta
     5101 tttagcttct ctagcttgcc gggataaatc atcatgcctt tgctataaaa ataatcatgc
     5161 atagattgaa aatcataacc tgcacaatga ggctcaagaa tggaagtaat gatcttggaa
     5221 tgatgctctt cgggaatgat ataggttagg cctaaccggg ctaacccgtt aattaaggtt
     5281 ttccaggatg tcgcgtacct ttcgtacctt ttatccaccc cttcctgctt taattcctca
     5341 atcgcttgtc taagcgcata taaggtttgg actgggggag taaaccgcat ctgcccatgt
     5401 tccacaaagt agttatattg agcatacaaa ttcaaataat agcttcttgg tttctggcct
     5461 ttcaaattct ccaatttgct tttttcggcg atcacaaacg aaaccccggc cattccctgt
     5521 aagtttttgt tggagcttgc cgccaggtag gcaatgttca tttccttcaa ttgaattgga
     5581 acggccgcaa atgagctcat ggcatccacg atcatgtcga tttgatatct tttgcacaat
     5641 tctccgatat ccttcacctt gttaagcagg ccagttgtcg tctcatgatg tacgacggcc
     5701 agatgggaga cagtgcgttc ggaagattgg atatacctct ctaattcggc caaatcaata
     5761 gcatcatcgg gagaactttt gaactcaaaa taatccactc cataaacctt cgctatctcg
     5821 cacatccgtt ttccataggc cccattgctg acaatgatta ctgcatcgtg attcgggacc
     5881 gaactgatga tggattccac cgctgcagta cctgatccgc caaacaatac ggtcgcataa
     5941 tcatccgggt cagcaaccaa ccgggtcagt tctgtagaaa tgtactccat gatttggcca
     6001 aactcggctt cacgaggaca aatatccgga accacctgtg aacatttcac actttctgta
     6061 gtcgttgccg gcccaggggt tagcaaaatg tttttcttga cgacagaact catgaaccgc
     6121 ccacttcctt gcccttcaaa ggatcgttat gaataaaacg ctgcagacgt tcttttactt
     6181 cgagaggctt catatgcgga cgagcaagct gatccttaga atctttggat attttcagac
     6241 acaaaaacgt aagttctcta ttcattttcc attcttgtaa aaagactttt agttcctcga
     6301 gactgtgaac aagaatcgac tttgtatacc cacaggaagc agcaatatct ataaaatcaa
     6361 tattatgcga taccgtactt tgcccgcctg ttgattcatg ggcattatta tctagcatga
     6421 tatgaatcat attggccgta tggtagtacc cgttggttgc caggctcccc atacgcatca
     6481 acagagatcc gtctccgtca atcacgacaa tatttttgct tggttggctc agagctaacc
     6541 ccagtccaaa agaaccgatg caccccatag aacctaccat gtacaggttg ttatctgcat
     6601 cttcaatttc atatagttcg cgcccagttt taccagttgt tgcgagctgg acggtatggc
     6661 tgtctttcat ggagttaatc gcacataatg catcatagcg cgtaggcatt tgatgattcg
     6721 cacgaccatg ctgccggatc tgatttaaat ggatggaggt ttgctgtttt ttcaatggct
     6781 ctttgtcgaa cgtgcctttt ttaacgacaa aaaagaacgg gcgattccgg gcaatttgct
     6841 cattagcctg gatcaattga ttttttacct cctctaaatc cttggagaga tactgccatt
     6901 ccacatccat caaatccagc atttgcgttg taatctggcc catcagttca tgctgaggct
     6961 cgtcaggtat ccccggttct ccgcgcagac tgacaaatcc aagcagagga atacgaaaag
     7021 ggtaagtaag ggaggtcaat ggcgaaacag cgttggtcag ccccgaattt tgcataagga
     7081 ctaccgattt cttcccccct atataagctc cggatgcaat ggcgaccgca tccccttcgt
     7141 tagccgctgc aacataatcg cattcgttta tggcataatt gatcaagctt ttcaagaagg
     7201 agcatggaac accgctgaaa aaggtaaatc ctaatttttt cagctcttct cctaacaatt
     7261 tcgtgtccat tatacgcgct cacccgaatc cggttctgac gatggaagat atttcttttc
     7321 cgcagcttgc agctcttcga ccccttgaag ccggaatact tcttcgaggg ttgcgacttc
     7381 cttttcgaca tgaacaaggc tttcatcccg ataaattcgg ccagataatt gtttcatggc
     7441 ttgaatggat gctctcaaat tatggtttgc ccaaatcaca aggctaatcc ccatctcctg
     7501 aaacctgacg gttggagtcg tatagtattt ggtaggcacg atcactactg gcaatcttcc
     7561 agcccattct ttcatgaacg cttcaatctc tgcggcatcc gatcttttgc tgtgtataaa
     7621 tacggcatcg gctcctgcct ttcgatatgc ctccgcccgc tgcagcgcca ctttaagccc
     7681 actcccggta ataaatgcct ctactctggc caccaccgta aaatccgtgt ccgtctgcgt
     7741 atctttcatc gctttaattt tcccggaaaa ctcttcgata tcagccaaag tctgctcttg
     7801 accgttaatg aaagaattcg ttttggggaa ccgcttatct tcgatacata cccccgcaat
     7861 atggcgctgc tccagtttct tcaccaagcg ccttgcattg ttgaagttgc cgtaccccgt
     7921 atctccgtcc aacaaaatcg ggatggaggt agcgtcactc atgaattcca aaacatccaa
     7981 aacctgcgtc caggaggcct cattgttgtc ccttactccc atcgctgcag agatggataa
     8041 cccgctggcc caaattcctt taaatcctgc ctcctccaca attttggctg acagaccatt
     8101 atgagcctcc atgataaact ctggtgtttg tgaattgacc aagtctctaa gttgctttgt
     8161 ttttttcatt gaaactttct ccttctcccc taaaaataac gtgcatggaa tctactttcg
     8221 aataagactc ttgtttctca tgatggtgtt gatcatagta ggatcgggaa attgagtaaa
     8281 tagcatatgt cctgggtgtg aattggcctc gataatccaa atatgacctt ttttatctat
     8341 ggcaatatca acccccaatt cgcgaaccgg atgccgttca ttgatctttt tggcaataat
     8401 gacggatagt ttggagattc tacgaaaata ggcatctgct ttcgcgcggt tgtgcttaaa
     8461 aaggctgaat agcactcgat gcaaggatac tgcatgccct cctttaagat aattggtaac
     8521 atacttatga ggtgccgcga cacgggcagc caccccggaa ataacccatt tcccccttgg
     8581 cttctgtaaa tatatcctgg tgtcaaaaat cgacccgtgg tacttagcca accgaagtcc
     8641 tttctgtacc aaataccgat gtctggattt ccggtatgac ttaattgctt ttaagacaaa
     8701 acgagatcca acaaactttc gacttgaacc gctacgaacc tcatatcctt ttttcaatct
     8761 cttgacccgg atgatcccgc tgccaccact cccgtgattg ggttttatga agaccgatga
     8821 ataagtattc agcatccgcg aggtccttga atccgtaaac cagtgggttt caggtaaatg
     8881 cgaacgcaaa acgggatgtt gcaacatttc tttatgcttt ttcatttttc caataggcac
     8941 tagtcatccc tcttatcttt ttgggttttt gcgcatacag tatgcatatg catccagatc
     9001 cccttctgcg tgggccgcta cctctgctag aaaccaagat ttatgtcaca aaaaggcatg
     9061 tcccagctgt tataaatacg ccccccttgg aaacaccctt tcggacagac tcggggttcg
     9121 gaccacagaa aataggctgt cacacactgc acttgaaata aaacccattt tgaccgaaaa
     9181 tataaagggt aattatgtaa ttaattcaac tattttgtta ggaggaatat gtatcatgtc
     9241 aaatatcttt aatcggaagg tcaggtttag cttcttactc gtagccatta ttgcgttcgt
     9301 tattcaaaat tctacaggag acattcatgt agcccgagct gcggacaatg taattaatgc
     9361 caaggatttt ggcgttaaag ccaactcgaa ttcctcacag tcaaaggaaa ttcagaatgc
     9421 attaaagtat ttctacgacc gaggaatgga gggaaccgtc tattttccaa aaggaacata
     9481 cttggttgac gaatctattc gtttatatgc cggggttagc ctgaacggtg acggaatggg
     9541 aaaaacgatt ttcaaaaaga cagggtctaa aagccaatac gtcgttggcg atccgattct
     9601 acgaaacaat tctgaccgac tagacgtgaa gttatctaat ctcaccattg atgcagaccg
     9661 tgccaaccgt gaagcccgtg gcgaaagtca ggtaggcggt attattatgg aaatggccgt
     9721 ctctcacttc acgctggatc acgtggagat ttgcgataca acgatcggag cccttcttcg
     9781 cagaacgaga gattcagaga ttaccaacag ccgctttgac cgaaataatg gacatgctat
     9841 tgccactgga cacgagagct ttccggcagg cgagttccgc aacgtcaaaa ttacgaataa
     9901 ccagattacc aattcgggcg gcggcagtgg aatcaattta tcacgcgcaa cctacacgac
     9961 agtcactggg aaccaaatta ttaacaagac ccatcaatct gatggatacg caggcattcg
    10021 catccctaat aatggcgcca acaatactgt aaacaataat gtgattgaaa attacccgcg
    10081 cgggatcttt gtcctgactg gagcaacagg taacaatgta tacggaaata ctgtaaaaaa
    10141 tgcatccctg caaggtcttt tggtccaatc ggatggcaat acgtttaccg acaacgaatt
    10201 tattcaaacc aattcctcac ttactccaga ggcagtcatt cgccttgctg acgcaaacaa
    10261 caacaaagtt attggtaacg agatgaccac atactccggg ttctccaata taggaatacg
    10321 ggtcaccgat tccaactcca atgaaattaa ggacaacatc acagatacta gaggtaaatc
    10381 agtcagtatt gaaggcgggc gtaataacgt caatacaggc aaccgcaatc ggtagaaatt
    10441 ttatgaatta cctactatgc gagtacgtcg gtttccgtta caatatgtca gtgtgattct
    10501 ggcatcggca gattgacgcg tacttgaaca ttattggagg cttctatttt ttcatgcaaa
    10561 acgaatctca ttctaacgta aaaatcataa cggccgatcc gagtgcgatc ggcctgtttg
    10621 gcttggctat cgtaacgctt gtggcttcat cccaaaagct tggtctcacc gaaggcttaa
    10681 gcttcatcat cccttgggct atatttctcg gtgcttttgc gcagctgttt gcctccattc
    10741 aggatgcaaa acataacaat accttcggca tgacggcatt tggtgcttac gccttcttct
    10801 ggttagccgt agctagtagc tggatgatta aaatgggcgt attcggccct gagctggcgt
    10861 ctgctgtaga cggcaagcag ctcggctttg cctttgcggg ctatctcatc tttacgctct
    10921 ttatgaccat tggagcgatg gagacgcata aggttctatt ctttattttt gtgttgattg
    10981 attttctgtt cctcggtctt agcttcgatg cattcggcgt tgcaccagag atattccata
    11041 ccatcgccgc ttatgctgaa atgggcattg gtctactctc actgtacggt acaggagctg
    11101 ccgttctgaa tgctcatttt ggccgtacat tcctgcccgt tggacgtcct ttcggcattt
    11161 tcaagccacg tccttaactg tatatgtaaa cccacaaagc cgcctttcgc gccgatccgc
    11221 gtaaaggacg gctttatttc ttttccatca ctccctccgt atcaaaaaat actaaaaaga
    11281 gtcgtttagt gaatataaaa gcccacaacg ataacaatat acataaattg caatcaaagg
    11341 gatattttga aaatgacaca agacgaatct cgtaccacat ttccgcaatt tcccgaatcg
    11401 tattggttag cttcaacaac tgacatcccc aatttcccca aacttagtga agatattcag
    11461 gtggatgttg ccattgtagg tgcggggatt actggcatta ccactgctta tttactttct
    11521 aaaaaaggac taaacattgc agtcgtcgac acagggcgga tacttcatgg gacaacggac
    11581 catactaccg ccaaaattac cgcacagcat gatttgatct acagcgagtt tctttcacat
    11641 tttggcaagg aaaaacccgg ctttattacg aagcgaacca caacgctctt caatttatca
    11701 agcaaacggt agaagagttt aatatcaatt gtcaatttac agaagaagat gcctacgttt
    11761 atacatgtgc agatacgtat gtggaaaaaa tatctgccga atataaagcc tagaggaact
    11821 tggcatcccg ggaagttata tcgagcaaac gcctctgccg ttttcaacta aagcagctat
    11881 taagatgaaa aaccaagccc agtttaatcc ggtacctttc ttaagatatt tggcaaacca
    11941 agtcatccgt cagggcgaga aaatttatga acaaaccacc gttgtaggtg tggaaaaagg
    12001 aaaccccgca atcatgtcgt atcctcctcg cattttccat tcaatgatcc aaacggtctt
    12061 tattttgcgc gattgcatgc cgaacggtct tatgtactag cagtcaaaac cgataaaatc
    12121 tatccgggtg gtatgtacct aagtgcggaa accccgaaac gttcgcttcg ctccgtaatg
    12181 gttaacggag aaccgatggt tatcgtcggt ggggaaggcc acaaaacggg acaaggaatc
    12241 tgtactttcc agtactatga agctttaaaa aagttcacgg agcaaacatt tggattaaag
    12301 gagatcgttt atcgctggtc ggctcaagac ttgtatacgt tagacaaact cccttatatt
    12361 gggcaggaac tatcgagcat ttctaacatc ctcgttgcta cggggtatag aaaatggggg
    12421 atgaccacaa gtgtagcggc agctttatta aatacaaatc tgattaccag agaggaaagt
    12481 ccgtaccagg attttttctc cccttcaaga ttttatatgg accccgatat taaaacattt
    12541 gtgactcaaa atgcgaatgt ggctaaacat ttgattgctg ggaaattggg gatcaactac
    12601 aaaaaagccg aagaactgca gcacgacgaa ggggcggtca ttcgggtaaa cggcaaaaga
    12661 gcgggcgcat accgagaccc acaaggagca ttacacctag tggacacaac atgcacccat
    12721 atgggttgcg aagtcgagtg gaatgaggcg gaaagaacat aggattgccc ttgtcatggc
    12781 tcacgctttt catatcaagg cgaagtcatt gaaggaccgg caaaaaaatc gcttggcaag
    12841 gttgaattcg acaagagccc tacatgaaga gctacacccc agtaacccaa ccttttcata
    12901 gctctgaata gacatagtta cgctggacaa catacctttg agaatcataa aagaaaggtg
    12961 atcctatgat aagccaacgg tctgcattag cggcgcatga gtccctagag atccacgaag
    13021 cgcttaattt taaaacgtta tgcttagcca agtccaaatt aatgcagggc ttagtattcg
    13081 atcaagagct aaaggattta atggaaaaag atgttcagca atctatacaa gctattgccg
    13141 atttgcaagc attgtatgtt aaagcaccg
//
