LOCUS       NZ_CP017968            24120 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Paenibacillus polymyxa strain YC0573 chromosome, complete genome.
ACCESSION   NZ_CP017968
VERSION     NZ_CP017968.3
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 6126117)
  AUTHORS   Liu,H., Hou,Q., Liu,K., Wang,C., Ding,Y. and Du,B.
  TITLE     Complete Genome Sequence of Paenibacillus polymyxa YC0573, a Plant
            Growth Promoting Rhizobacterium Isolated from Rhizosphere of Tobacco
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6126117)
  AUTHORS   Liu,H., Hou,Q., Liu,K., Wang,C., Ding,Y. and Du,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2018) Department of Microbiology, Shandong
            Agricultural University, No. 61 Daizong Street, Taian, Shandong
            271018, China
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 6126117)
  AUTHORS   Liu,H., Hou,Q., Liu,K., Wang,C., Ding,Y. and Du,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-NOV-2016) Department of Microbiology, Shandong
            Agricultural University, No. 61 Daizong Street, Taian, Shandong
            271018, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: canu v. 1.3
            Genome Coverage                   :: 140.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 04:02:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,505
            CDSs (total)                      :: 5,362
            Genes (coding)                    :: 5,219
            CDSs (with protein)               :: 5,219
            Genes (RNA)                       :: 143
            rRNAs                             :: 13, 12, 12 (5S, 16S, 23S)
            complete rRNAs                    :: 13, 12, 12 (5S, 16S, 23S)
            tRNAs                             :: 102
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 98 of 143
            Pseudo Genes (incomplete)         :: 53 of 143
            Pseudo Genes (internal stop)      :: 19 of 143
            Pseudo Genes (multiple problems)  :: 23 of 143
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:01:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1519294
            Orig. end                         :: 1543414
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017968.3.
            On Feb 23, 2018 this sequence version replaced NZ_CP017968.2.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24120
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="7"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..24120
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24120
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14120](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14120
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(10..23)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
     gene            232..1152
                     /locus_tag="PPYC2_RS06745"
                     /old_locus_tag="PPYC2_20030"
     CDS             232..1152
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821230.1"
                     /locus_tag="PPYC2_RS06745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_20030"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_068938660.1"
                     /transl_table=11
                     /translation="MQQATGQVPVIRMEGVSKIISSKAIVDDLTLEVPAGQVFGFLGPN
                     GAGKTTTIRMMVGLISISKGDIHICGDSINTDFEKAVAHVGAIVENPEMYKFLTGYQNL
                     QHFARMSPGVTQERVEEAIRLVGLGNRIHDKVKTYSLGMRQRLGVAQAILHRPKLLVLD
                     EPTNGLDPQGIRELRDYLRQLTRTEGITVFVSSHLLSEMELMCDRVAIIQSGRLVDIKQ
                     LKNTGEEVHKAEIAFEVNDAEQAYALAGAGRVEGNQLLLHLEREQIAEMNSLLAANGIK
                     VYAIRPVARTLEDQFLEVTGGGVIG"
     gene            1145..1927
                     /locus_tag="PPYC2_RS06750"
                     /old_locus_tag="PPYC2_20025"
     CDS             1145..1927
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369846.1"
                     /locus_tag="PPYC2_RS06750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_20025"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_071559036.1"
                     /transl_table=11
                     /translation="MGDFFKLVHNENLKIYLRVRTWIMLGLLAVITAVIPMLISLVSDQ
                     VSVWDGIALTTLFTFFLNTTFTVIVAADSVAGEFTWGTIKLLLIRPWTRSKILLSKYLS
                     VILFSLLGTIILILMVTLSSWLMLSKDAPAGSVPLFSDPISYVTLNFLYSYIALFVTMA
                     FAFMLSAVFRSSALAIGLSLFMMFTKTVYNTIGLFSTDRFEWTKYVLFTHMDLKKYLDM
                     PPGTVSSSLTFSLTVLAAYYVIFIAIAWVVFVKRDVST"
     misc_feature    2081..2097
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.86"
                     /tool="antismash"
     gene            2171..3255
                     /locus_tag="PPYC2_RS06755"
                     /old_locus_tag="PPYC2_20020"
                     /pseudo=""
     CDS             2171..3255
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426473.1"
                     /locus_tag="PPYC2_RS06755"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_20020"
                     /product="AI-2E family transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLQNNRFFRLTTGIVMLLLIIYLGTKVSFIFSPLVSLVSLLVVPL
                     MLSFFLYYLLRPIVDVMERRKIKRSISILLIYLVIGVLLFVFSWGVWPTLRDQVTNLFE
                     NAPKLIKSLVDQLSQWRHNQSLRQVLPPGEDPLSQLSDTLNEAFSTLSDYSVKLVSFVS
                     YFFIVLATFPILLYYMLKEGSKFGPKMLNFFPKKYHKDALEVMEDIDSALSSFIVSRVL
                     INVALGVMMFLGFLIIGLPYALLLAVISIFLNFIPYVGQWLLLYLWLLLDYSNHLRWHS
                     GPWSW"
     gene            complement(3295..3756)
                     /locus_tag="PPYC2_RS06760"
                     /old_locus_tag="PPYC2_20015"
     CDS             complement(3295..3756)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369848.1"
                     /locus_tag="PPYC2_RS06760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_20015"
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="WP_071559035.1"
                     /transl_table=11
                     /translation="MFKESKKKLSAPAMDTLLANGTSFEGTVEAEANIRIDGHFQGDIR
                     STRTVVVGESAVVRSDIIAQDVILAGKVFGSITTEGRLTITPTGELYGNTATTALVISE
                     GGILDGTIQMNRTKDVELSTSTDESNDETQSSFSKNKEDSQAALQSEAG"
     misc_feature    complement(3800..3818)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.46"
                     /tool="antismash"
     gene            complement(3802..4833)
                     /locus_tag="PPYC2_RS06765"
                     /old_locus_tag="PPYC2_20010"
     CDS             complement(3802..4833)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426474.1"
                     /locus_tag="PPYC2_RS06765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_20010"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_028543094.1"
                     /transl_table=11
                     /translation="MKKGSLNRRMTLLVIRDAQQPPKQLQCSTAAVILVPTLVIASIST
                     LVIGLQIHSSHIISQMETNLAVQSLQMEVTVADKDAAIGRLRQEVMELTNQATNIRERL
                     QRVTELEQQMQQFIRKHGNSSATSNHKKTMTPLSWDASGHIGGELIAVHENTALLTRQA
                     MDDFQEIESLLDTVERTVPRSIQQANAVQQNLERKQAAQLLQTRRLALAEQGNPSVWPV
                     GSRRMTSSFGYRSDPFTGRSAFHSGVDIAGQTGDPVYAAGAGTVLEAASSGARGKCIII
                     QHPDGLQSWYMHLSGMQVAPGDRVHKGQTIGLLGSTGRSTGPHLHFQIVKHNQPVDPLL
                     YVQ"
     gene            4980..6410
                     /gene="cls"
                     /locus_tag="PPYC2_RS06770"
                     /old_locus_tag="PPYC2_20005"
     CDS             4980..6410
                     /GO_function="GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cls"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686424.1"
                     /locus_tag="PPYC2_RS06770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_20005"
                     /product="cardiolipin synthase"
                     /protein_id="WP_028543093.1"
                     /transl_table=11
                     /translation="MLWLLLVLIVFIFQTGTILLFEFRKPSKAVAWLFILFCFPLIGFV
                     VYYFVAQDYQKRKMVRKGGSQLFREFRERLWAQSKVIEHVEQMHNPHFKHQERLFNQLI
                     RMSENPLTGCNRTRVLTNGEETFEAMLTAMEHAQHHIHVEFYIFRADEIGRKFQEVMIR
                     KAREGVKVRFVVDGVGSYHLPYSFIRTCSEAGVEFHYFLPPFFATLDRRINYRNHRKIV
                     VVDGMIGFVGGINVGDDYLGKYPKVGFWRDTHLQIEGDSVYFLQNAFLSDWKLASGERL
                     MDVNLFPPHTCTGDEEVQILSSGPDQVWDTIQEMCFGALTVAKKRIWITTPYFIPDLGI
                     YEALKLAAVSGVDVKIIIPYQSDSKLVHLASLSYVQELLEAGVEFYQYRKGFIHAKVVI
                     VDDLLGSVGTANMDMRSFFYNFELTAIVFANSALERLSEDFVEDISNSSRIDLNVFRRR
                     PRSQKIAEILTRMLSPLL"
     gene            6606..7550
                     /locus_tag="PPYC2_RS06775"
                     /old_locus_tag="PPYC2_20000"
     CDS             6606..7550
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280287.1"
                     /locus_tag="PPYC2_RS06775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_20000"
                     /product="YitT family protein"
                     /protein_id="WP_023987451.1"
                     /transl_table=11
                     /translation="MSVVSKEVQNLSEITDVTGELTKISKIPANPKNKAKRLFQRAAMI
                     IFGATLMAVGLEIFLVPNGVIDGGVTGISIMASKITGYPLGIFLTLLNLPFLLIGYKQI
                     GKTFALSTLFGIIVMSIGTALLHNVSALTPGEPLLGAIFGGVILGVGVGLVIRSGGSLD
                     GTEIVAILVSEKTPFSVGEIVLFVNIFILGSAGFVFGWPNALYSMIAYYIAMKMIDITI
                     EGLDQSKSVWIISEKYRDIGDALTDRLGRGVTYLEGEGGFTGESKKVIFVVITRLEEAK
                     LKSIVEDWDPHAFVAIGNIHDVKGGRFKKKGIH"
     gene            complement(7620..8522)
                     /gene="ligD"
                     /locus_tag="PPYC2_RS06780"
                     /old_locus_tag="PPYC2_19995"
     CDS             complement(7620..8522)
                     /EC_number="6.5.1.1"
                     /codon_start=1
                     /gene="ligD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369853.1"
                     /locus_tag="PPYC2_RS06780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_19995"
                     /product="non-homologous end-joining DNA ligase"
                     /protein_id="WP_013309189.1"
                     /transl_table=11
                     /translation="MGQAVKGTITIEGQEIPITNPDKPLWPEAGVTKALYLRKLAVLAP
                     FLLKYCHHRLLTVIRWPHGIHGDFFYQKNAPRPRPDYIETALHDGIEYIVLGKLPQLLW
                     LGNQAALEFHPSLHEAGSKLPCEWMIDLDPSREVEPRIMEAASIVGEVLASLGLDSVPK
                     TSGATGVQIIVPIRTGITFDELRSIGLLVGQFVTEKHPHLFTLERLKKDRGTAIYFDYL
                     QHYQGKTLAAPYTPRARPGATVSTPLTWEEVRQDVSPLDYHLLNIEERLNQVGDLIDKV
                     PPQPVEDVLKHMRTKAHRT"
     misc_feature    8669..8682
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.44"
                     /tool="antismash"
     misc_feature    8670..8683
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.35"
                     /tool="antismash"
     misc_feature    complement(8672..8685)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.22"
                     /tool="antismash"
     gene            8736..10004
                     /locus_tag="PPYC2_RS06785"
                     /old_locus_tag="PPYC2_19990"
     CDS             8736..10004
                     /EC_number="2.8.2.-"
                     /GO_function="GO:0008146 - sulfotransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050656 - 3'-phosphoadenosine
                     5'-phosphosulfate binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309190.1"
                     /locus_tag="PPYC2_RS06785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_19990"
                     /product="sulfotransferase"
                     /protein_id="WP_104411498.1"
                     /transl_table=11
                     /translation="MIEKQGGGLVFLLSVPRSGSSLLTAILQNHSRLFATQEMWFLLSL
                     YDLPQSQARPYGGTGILRQFFKGMVPSDVLEQASRSYALEIYNGLLQGTTADMLIDKSP
                     RYYTVLEFIDRLFPAARRLWLIRNPLAIVASFKKVNQLRNGRFQLLEELGSPHFNMKMT
                     DITVGLFRYAHYFATPHPLAYPLRYEQLVSNPTMEIEKLCSFLGIKYEPGMEKYGDFAD
                     TPKSSLFYSMGAGDPFVGEHEQAHQDSVHSWQHLLSKTEIELYCRSIGSRMFRQLGYAE
                     ALEQAEQMTGVRFEDEPDIELLSQRTQQFLQQSGFEWKAAYRMLEEQDADNRELVINAT
                     CHVAPQDPARMQVDQIVNDRRIQSLENRLAHSYEERNRLIAQLQSYQRPNQSLRSRSLF
                     ARKLGRLASVALSSIGKEKGGRT"
     gene            10001..11926
                     /locus_tag="PPYC2_RS06790"
                     /old_locus_tag="PPYC2_19985"
     CDS             10001..11926
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369855.1"
                     /locus_tag="PPYC2_RS06790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_19985"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_071559034.1"
                     /sec_met_domain="GATase_7 (E-value: 6.6e-20, bitscore:
                     69.6, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.2e-25, bitscore:
                     89.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAIAGIYSFGHESVSTEEGGKMMQALRKYPADRVCAWCEGSIFL
                     GCHAQHVTPESVHERLPFYDELRDLAITADAIIDNRSELFERLGVEQERRQDITDSELI
                     LLAYDKWGVEAASYLIGDFTFVIWDAKEHRLYGARDMTGNRTLYIYQHDRGFAFSTVVA
                     PLLALSSLRKELHEPWLAEFLSIRAMQESVDIGTTAYKHINQLPPAHWFTMEEGKRTLH
                     KYACLDEVEPLRLKTGGEYIEAFREVFTQAVTARLRTHRAVGAALSGGLDSGAVASFAA
                     PSLHLQQKPLHAYSYVPVQDFTDWTPPTLLANERSYIQSTARYVGNIHENYMDFEGKSP
                     FSEIDIWLELMEAPYKYFENSFWIRGFYEKAQEHNVGVLLTGARGNFTVSWGPALDYYA
                     RQFRRLHWLQSFQGLWRYSKLTGRRMSHLLPVMLKKATSLESRSWLRRSNRSPVPSLIH
                     PEFAKRMHVEDIPVLSGTGWMKNADQTRKEKFSNLAIANKNGVVATKLSLRYGLWERDP
                     TGDSRVIRFCLSVPFEQYVQNGRDRALIRTAMRDHLPDDVRLNQRVRGVQPADWLHRML
                     PCWDTFMGELQLMCHDLRAAEYLNIEFIKTAMAKLHHPRPEQASDPNIRLLMHSLIVYR
                     FLCRLN"
     gene            11979..12107
                     /locus_tag="PPYC2_RS06795"
     CDS             11979..12107
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369856.1"
                     /locus_tag="PPYC2_RS06795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_023987454.1"
                     /transl_table=11
                     /translation="MSKKEWQEPTIEVLDINQTMAGKGWKQIDWVSDHDADLHNPS"
     gene            12298..13341
                     /locus_tag="PPYC2_RS06800"
                     /old_locus_tag="PPYC2_19980"
     CDS             12298..13341
                     /EC_number="2.7.1.24"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010349787.1"
                     /locus_tag="PPYC2_RS06800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_19980"
                     /product="dephospho-CoA kinase"
                     /protein_id="WP_071559033.1"
                     /transl_table=11
                     /translation="MHDRSANVSWTKYIAFGLRIASELNLPELILAAPEAVEDVVIRQA
                     DLTAWSGQLEQANFVMLDERFMFQIPGTAIYAVREGKEIEVSIFSGADPDTVRLFVLGT
                     CMGVLLMQRRILPIHGSAVVIGERAYAFVGESGTGKSTLAAAFRQAGYQMVSDDVIAVK
                     ATASSAIVYPAYPQQKLGLDSLLQLEALRENKHARKRNNIRSLTDGNSVMPQYSDLRML
                     AGELNKYAVPAVDEFFNDPLPLGGVFELVADSPIRALMREGELVAVTEQPLNVLECLHT
                     LLQHTYRRVIIPRMGLSEWSFDTAARMARKVEGWRLLRDSSVFTASEVVQRVLDIIRKE
                     EKSYGSH"
     gene            13328..13630
                     /locus_tag="PPYC2_RS06805"
                     /old_locus_tag="PPYC2_19975"
     CDS             13328..13630
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309193.1"
                     /locus_tag="PPYC2_RS06805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_19975"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_053324868.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 6.2e-25,
                     bitscore: 85.4, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.7e-16, bitscore: 58.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAATNSAKDHYRVIYGEEVYVSDMDGEKVMMSINTGKYYNLGFTG
                     GRIWELAESGPSLGDIVTVLTNEYEVDEEQCRQQVHTFVAELEREGLLKLLRESV"
     aSDomain        13376..13609
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_PPYC2_RS06805_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="3.20E-27"
                     /identifier="RREFam002.1"
                     /label="PPYC2_RS06805"
                     /locus_tag="PPYC2_RS06805"
                     /protein_end="94"
                     /protein_start="16"
                     /score="85.4"
                     /tool="antismash"
                     /translation="EEVYVSDMDGEKVMMSINTGKYYNLGFTGGRIWELAESGPSLGDI
                     VTVLTNEYEVDEEQCRQQVHTFVAELEREGLLK"
     gene            13632..14120
                     /locus_tag="PPYC2_RS06810"
                     /old_locus_tag="PPYC2_19970"
     CDS             13632..14120
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821220.1"
                     /locus_tag="PPYC2_RS06810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_19970"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_071559032.1"
                     /sec_met_domain="PF13471 (E-value: 2e-24, bitscore: 84.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIQRLLLLSPEVRKLLPEAWLELGWARLRQRRSFGDYSRVWGIC
                     MEETPWQCDVRQEKSIQQISHAVELASRYTPWRSSCLVQAAAAMTLLGRRKLDCTLYLG
                     TAKNAAGRLAAHAWVRSGPIYVTGKREMEAFTVVGIFGRRAVMATNTKKMKDKGSSLL"
     gene            14149..15645
                     /locus_tag="PPYC2_RS06815"
                     /old_locus_tag="PPYC2_19965"
     CDS             14149..15645
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426482.1"
                     /locus_tag="PPYC2_RS06815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_19965"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_071559031.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 1.2e-80, bitscore:
                     269.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTKSVLELANWNEDQELTLLLSLLGKDVSHWQDKTAATQLREMD
                     WVRFLRLTEHHRVVPTVYLQLKTLNHPFIPAELLRNLQAQYHRNTLRMLHLQAEAERLT
                     RLLIVNGIRVLMLKGPALAQQLYGDVSLRTSKDIDLLIAPDDMDEAEHWMKEAGYASKS
                     GEVRVLGSWKWKDHHASYLHPQKRVEIELHWRLHPDGGGEPSFDELWNCRKMGKAAGTS
                     RQVPLGPADNRTVMTSCMYTLGSEHQFLYLSAHGARHGWFRLRWLVDIDRLAVCAVDWE
                     ALLPMMRRYGGLPAGGQAWALAAALLGTPIPESMRPVSATRQAHRLALSALAFMQASVP
                     APYPIAHGSGTGRLAPSELLHSRALAEQAEAAPPDGGASVCGTCGEAAMLATSGVTSIT
                     EDASNDDHSPMSTATRCAPITPAVASSQVMTRNTAAAHQPVSRTYLLSLKEPRHRLWYL
                     ISRLFPSTGDSAVFPLPRQLHFLYIPLRPFLWLKRRFSKH"
     gene            15788..17593
                     /locus_tag="PPYC2_RS06820"
                     /old_locus_tag="PPYC2_19960"
     CDS             15788..17593
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821218.1"
                     /locus_tag="PPYC2_RS06820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_19960"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_071559030.1"
                     /transl_table=11
                     /translation="MVHLRLYMTKLYSVNGGALFLNIGCMIIVSLLEGFGIYMLVPMLA
                     AIGVFVGHSGMPFLSGGLEHFLPFIPKSWLLPGMLMVFIVLLTGQALLQRYQSILNSRI
                     QQRFMRSLRIDVYTSFMKAQWAFYLRQRKSDFSHVMTTELARVSQGTNLLLQLTTAVMF
                     TMIQIALAFWLSPSLTGLVFLSGLGLFVVFRRSIRNAKQLGDRTTELSQVYFAGITDHM
                     NGMKDIKSNLLEAANIHWFRSLTQRMEDNTTQFVRQNATTQFFHRTAAAVFVACVIFTS
                     LQWLHVTPEKLIVLILIFSRLWPRFALIQASLEYIMSMISAFESVTKVQQECEAFTDPS
                     LIVSASVRQPLSLRHGIECSHLDYRYDGAAESALRQINLFIPARGMTAIVGKSGAGKST
                     MVDVLMGFLRPTGGQITIDGLVLDDELLLQWRQSFGYVSQDPFLFHATVRENLMLADKD
                     ASEQQLWEALHFAAADNFVSRLPEGLDTVIGDRGIRLSGGERQRLVLARAVLHHPSVLI
                     LDEATSALDGEHEAAIQAALERMKGQMTLIVIAHRLSTIRHADQIVVLDQGEVIQQGNY
                     HQLEQEERGAFSQLLSYQSSVTATP"
     gene            complement(17616..18530)
                     /locus_tag="PPYC2_RS06825"
                     /old_locus_tag="PPYC2_19955"
     CDS             complement(17616..18530)
                     /GO_function="GO:0045027 - DNA end binding [Evidence IEA]"
                     /GO_process="GO:0006303 - double-strand break repair via
                     nonhomologous end joining [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309197.1"
                     /locus_tag="PPYC2_RS06825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_19955"
                     /product="Ku protein"
                     /protein_id="WP_013309197.1"
                     /transl_table=11
                     /translation="MHTVWKGAISFGLVHVPVKMFSATEDKDISMRYIHKECGSPLSYV
                     RKCPVCDKEVEWEEIGKGYEYEKGKFVMFDKEELEQVSGQADKNIVILDFVDLQEIDPI
                     YFQKTYYLSPDQAGSNAYKLLMNAMKDTGKIGIAQISIRSKSSLAAIRVLDECLAVETM
                     FYPDEIRPIAQVPNLPGQEEVKEKELTMAKMLIEQLSTPFDAAKYTDQYRERLLDLIQH
                     KVAGEEVRIAPTQPQTNVVDLMAALQASIEAVQPVVTDPGPAAKKRPARKPAAPTAQQA
                     VAGENISPTPVKKKRSTAKRKET"
     misc_feature    18720..18737
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.46"
                     /tool="antismash"
     misc_feature    complement(18864..18877)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.9"
                     /tool="antismash"
     gene            19359..19598
                     /locus_tag="PPYC2_RS06830"
                     /old_locus_tag="PPYC2_19950"
     CDS             19359..19598
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369863.1"
                     /locus_tag="PPYC2_RS06830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_19950"
                     /product="hypothetical protein"
                     /protein_id="WP_023987461.1"
                     /transl_table=11
                     /translation="MSGKSYPQQIRHRVGQSQIAFRGPAGGEQDALPPEFALSHGIRPP
                     FPVAVAHVDLEAVVSTSPSHSIPSLDVERIIDED"
     gene            19655..19834
                     /locus_tag="PPYC2_RS06835"
                     /old_locus_tag="PPYC2_19945"
     CDS             19655..19834
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309199.1"
                     /locus_tag="PPYC2_RS06835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_19945"
                     /product="H-type small acid-soluble spore protein"
                     /protein_id="WP_023987462.1"
                     /transl_table=11
                     /translation="MNVERAKAIYDSSENIAVQLDGKPIWIEHVDQANGMATVQIGSRP
                     GNTQTVRVDRLEEQ"
     gene            complement(20075..20731)
                     /locus_tag="PPYC2_RS06840"
                     /old_locus_tag="PPYC2_19940"
     CDS             complement(20075..20731)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369865.1"
                     /locus_tag="PPYC2_RS06840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_19940"
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="WP_023987463.1"
                     /transl_table=11
                     /translation="MNNREFIARRIAQEFKNGEVVNLGVGMPTMVVDYIPENIHIMLQA
                     ENGILGVGPKATQGKERLDCIDSGGNYVTTMEGACFFDSSLSFSIIRGGHVDITVLGAL
                     EVDEKGNLASWMIPGKKVPGMGGAMDLVVGAKRVIVAMEHVNKNGAPKILEQCKLPLTA
                     VNVVKTIVTEKAVIDVIPGSGLMLKEIAPGLSVEDVQLATEAKLMISPHLKAIAV"
     gene            complement(20728..21393)
                     /locus_tag="PPYC2_RS06845"
                     /old_locus_tag="PPYC2_19935"
     CDS             complement(20728..21393)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429861.1"
                     /locus_tag="PPYC2_RS06845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_19935"
                     /product="CoA transferase subunit A"
                     /protein_id="WP_023987464.1"
                     /transl_table=11
                     /translation="MNNKVISAEEAVKQIKDGDTVMVGGFLAGGFPEELVRALVDTNPA
                     SNLTIISNDTGTPELSIYKLVKSGRVKRIFASYIGSNPETGRLLMTKEAEVQLFPQGTL
                     AEKIRAGGAGLGGVLTPVGVGTIVEEGKKKIQIDGREYLLELPLKADVALIRAHKADEA
                     GNLVINGSSRNFNLVMATAAEYVVAQTDEYVKTGEIDPNHVNVPGIFVDAIVKVGENA"
     gene            complement(21434..22174)
                     /locus_tag="PPYC2_RS06850"
                     /old_locus_tag="PPYC2_19930"
     CDS             complement(21434..22174)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686439.1"
                     /locus_tag="PPYC2_RS06850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_19930"
                     /product="acetoacetate decarboxylase"
                     /protein_id="WP_023987465.1"
                     /transl_table=11
                     /translation="MNQKDVLSLQSMPAASGSYGRPPCRFINREFFIITYESDPAAIRQ
                     AVPEPLQPDGSNTVSYEWIKMPDSSGLGSYEESGIVIPCTFHGEPCNFVAQMYLDNAPA
                     ILGGREIWGFPKKWAKPRLIVEETETLTGTLHYNNVLVATGTMPFKYNILDEKETAKAI
                     AKTQVNLKLIPDVDGTPKIAQLVAYNLENITVKGAWSGPARLSLIPHVNAPVADLPVKA
                     YIGGKHFIADLTLPYGRVLYDYLQ"
     gene            complement(22230..23414)
                     /locus_tag="PPYC2_RS06855"
                     /old_locus_tag="PPYC2_19925"
     CDS             complement(22230..23414)
                     /EC_number="2.3.1.9"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429859.1"
                     /locus_tag="PPYC2_RS06855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_19925"
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="WP_071559029.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.8e-05, bitscore:
                     22.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVALVSPLRTAVGSFNKTLAPLSAPELGATVMTACLQQSKLEP
                     SLIDQIYLGNVLQAGNGQNPARQAALKAGIPIDVPETTINTVCGSGLHAVALAYNSILA
                     EQGNIVLAGGMESMSNAPYLLRNARNGYKLGNGELVDSLVADGLTCPINHYHMGITAEN
                     VAEEYGISRLEQDEFSYQSQIKAVEAKNKKLFEEQIVPVMIKNKKETISFTEDEHIRGN
                     TTKEKLSQLKPAFKENGTVTAGNASGINDGAAAMLVVSEDKCKEHALKPLAYIKGYSLV
                     GVDPAYMGMGPVKAISSLLKQQGMSIDDIDLFEINEAFAAQALAVLKELGINPEKVNVN
                     GGAIAIGHPVGASGARVLVTLVHEMVRRSSRYGIASLCIGTGMGIAMLVENALI"
     misc_feature    23406..23419
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.09"
                     /tool="antismash"
     misc_feature    23733..23747
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 24.83"
                     /tool="antismash"
     misc_feature    23740..23754
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.75"
                     /tool="antismash"
     misc_feature    complement(23765..23778)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.68"
                     /tool="antismash"
     misc_feature    23799..23810
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 19.77"
                     /tool="antismash"
ORIGIN
        1 gtattacggt cactcagcat tacaagaccc gattcggcaa ctttgatatc gtacagcctt
       61 gttatgtgac gcaggaagat gagaagtggc gggtgctttg gatatacaag gacaaggaat
      121 agaggttgcg tggtgtttct aaaaggttaa atatggtaca atacttccaa aaccggaaat
      181 gtacagtaaa atggatcaca gcttcactcc ggatggaagg agtttcaaag catgcagcaa
      241 gcgacaggac aggttcccgt catacgtatg gagggtgtga gtaaaatcat ttcctcaaaa
      301 gcgatcgtgg atgatctgac gctggaggtt ccggcggggc aggtatttgg tttccttgga
      361 cccaatggtg cgggaaaaac gaccaccatc cgtatgatgg ttggcctgat ttcgatcagc
      421 aagggcgata ttcatatttg tggagacagc attaataccg attttgaaaa ggccgttgcc
      481 catgtcggcg cgattgttga gaacccggag atgtacaagt ttttgacagg ctatcaaaat
      541 ttgcagcatt ttgcgcgaat gtctcctggc gtgacccaag agcgcgtgga agaagcgatt
      601 cgtctggtgg gactcggaaa tcggattcac gataaagtaa aaacctactc gctcgggatg
      661 cggcagcgac ttggggtagc tcaggcgatt ttgcatcgac cgaagctgct tgtgctggac
      721 gagccgacca atggcttgga cccgcagggt attcgtgaac tgcgggatta tttgcgtcaa
      781 ttgacccgta cggaaggaat tactgtattc gtatcaagcc atttgttgtc cgagatggag
      841 ctgatgtgcg accgtgtagc tattattcag agcggacggc tggttgatat caagcaactg
      901 aagaatacag gggaggaagt gcataaggcg gaaattgctt ttgaggtaaa tgatgccgaa
      961 caagcttatg cgcttgctgg agcagggcgc gtcgaaggta atcaactgct gcttcacctg
     1021 gagcgggaac agattgcaga gatgaacagc ctgctggctg caaatggcat taaagtatat
     1081 gcgattcgcc cggttgcccg tacgctggaa gatcaatttt tggaagtgac gggaggcggg
     1141 gtcattgggt gatttcttca agctggtaca taacgaaaat ctgaaaattt acctgcgtgt
     1201 gcgcacatgg attatgctgg gattgctggc ggtcatcact gctgtgattc cgatgctgat
     1261 ttccctggtt tccgatcagg tcagtgtgtg ggatgggatt gcgttgacga cgttgtttac
     1321 atttttcctc aatacgacgt ttacggtcat tgtagccgct gattcggtgg ctggtgaatt
     1381 tacttgggga acgattaagc tgctgctcat ccgaccttgg actcgcagca aaatattgtt
     1441 gtccaagtat ttatccgtga ttttgttcag tttgctcgga acgatcattt tgatcttgat
     1501 ggttacgctg tcctcatggc tgatgttgtc caaggatgca ccagcgggtt ctgttccact
     1561 gttcagtgat ccgatatctt atgtaacgct gaactttttg tatagctata tcgccttatt
     1621 cgtgacgatg gcctttgctt ttatgctgtc cgctgttttc cgttccagtg ccttggcgat
     1681 tgggctgtca ctgttcatga tgttcaccaa aacagtttat aacacgattg gcttgttcag
     1741 cacagatcgt tttgaatgga ccaaatacgt tctatttacg catatggatc tgaaaaaata
     1801 tttagatatg ccgccgggta cggtaagttc cagtctaacc ttttcgctca ccgtgctggc
     1861 cgcctattat gtgattttta tcgccattgc ctgggtggtt ttcgtaaaac gggatgtttc
     1921 gacctaaatc gaagtgccat agagtaacac aaaggacgtt caaatgccta gcatttggac
     1981 gtccttttgt tatttcagga atttgcaaaa tcctcattta agactatttt atcctgtatc
     2041 tatgtcattt tttactacac attctacgtg caggggtata ttgtaatcta ttttcagcaa
     2101 gaatcaatca atagggtcac tttgcgttta aagaggtaga gagaaacaga acagaggggg
     2161 gccgcatgat atgctgcaaa ataatcgttt ttttcgtctg actacgggta ttgtcatgct
     2221 attactcatc atttacttgg gcaccaaagt aagctttata ttcagtcctc tcgtatcttt
     2281 ggtcagcttg ctggttgtac cgttgatgct atcttttttc ctctattatt tattgaggcc
     2341 gattgtagat gtaatggaac ggagaaaaat caaacgatct atctccatct tgctgattta
     2401 tttggtcatt ggagtgttat tgtttgtttt ctcatggggt gtgtggccta cgctgcgtga
     2461 tcaagttacc aatttatttg aaaatgcgcc gaagctcatt aaaagtctgg ttgatcaatt
     2521 gagccaatgg cggcataatc aatccttgag acaagtgctg cctccgggtg aagacccgct
     2581 gtcacaactg tcagatacgt tgaacgaagc tttttcgaca ctgtctgatt attcggtaaa
     2641 gctggtatcg ttcgtgtcct acttttttat tgtattggct acctttccaa tattgctcta
     2701 ttacatgctg aaggaaggga gcaagtttgg ccctaaaatg ctaaacttct ttccaaaaaa
     2761 atatcacaag gacgcattgg aggttatgga agatatcgat agtgcactca gcagctttat
     2821 cgtgagtcgg gtgctgatta atgtcgcgtt gggtgtgatg atgtttcttg gatttttaat
     2881 tattggcttg ccttatgcct tgctgcttgc cgttatttcg atttttctta attttattcc
     2941 ctatgtgggg cagtggctgc ttctatacct gtggttatta ttggattact cgaatcacct
     3001 tcgatggcac tctggtccct ggtcgtggtg atcgctgcac agcaaattca ggataattgg
     3061 ctgtcaccta tagtttttgg caagcagctg gatattcatc cgttgactgt cgttatttta
     3121 ctgttagttg gtggcgacct gctcgggatt ctgggtatca ttttggtgat tccattgtat
     3181 atgtgcggaa aaatcgtcat acgcaaggtg taccaattat ttttggaacg cagagtggag
     3241 gatattatgg aatgaatgga gaatgcactg gatttaaagg agtatatact gactttatcc
     3301 tgcttcggat tgcagagcgg cttggctatc ctccttgttt ttgctgaaac tagattgggt
     3361 ttcgtcgttt gactcatccg tagaagttga caactctaca tcctttgttc ggttcatttg
     3421 aattgtgccg tccaatatac cgccttcaga aatgaccaat gcagtggtcg cggtatttcc
     3481 gtacagttca cctgtcggcg taatggtcag tcgtccttct gtagtaatgc tgccaaacac
     3541 cttaccggca agaatgacgt cttgtgcgat gatatccgaa cgtacaacag cagattctcc
     3601 aacgacgaca gtacgagtgc tgcggatatc gccctgaaaa tgaccgtcaa tccgaatatt
     3661 ggcctctgcc tcaactgtac cttcaaagct ggtgccatta gcgagcagtg tatccatagc
     3721 tggggcggag agcttttttt tggattcctt gaacatgatg gttttccccc aatcttttat
     3781 tgtaaatatt ttcaaaaatc ctcattgtac atacagtaat ggatcgacag gttggttatg
     3841 cttgacgatc tgaaaatgaa gatgaggtcc tgtgcttctc ccggtacttc ccagcagacc
     3901 gatggtctgt cctttgtgga cacgatcccc cggagccacc tgcatgccgc tcaggtgcat
     3961 ataccagctc tggagtccgt caggatgctg gatgatgatg cacttgccgc gggctccgct
     4021 agaagcagcc tccaagacgg tgccagctcc tgctgcatag acaggatcac cggtttgtcc
     4081 ggcaatgtcc acgcctgaat ggaaggcaga tctgcctgta aaagggtcgc tgcgatagcc
     4141 gaagctggag gtcattcgcc gtgaacctac aggccaaacg gagggattcc cttgctcggc
     4201 aagagcaagt ctacgagtct ggagtagctg tgcggcttgt ttgcgctcca gattctgctg
     4261 tacggcattt gcttgctgaa tagagcgggg aaccgtacgt tccaccgtgt ccaacagaga
     4321 ttcgatctcc tgaaaatcat ccattgcctg gcgagttagg agggcagtat tttcatgcac
     4381 tgcgatcagc tcgcccccga tatggccgga agcatcccag gagagcggag tcatggtctt
     4441 tttatggtta cttgtggcag atgagtttcc gtgtttacga atgaattgct gcatttgctg
     4501 ttccagctcc gttacacgct ggaggcgttc acgaatattg gtggcttgat tcgtcagctc
     4561 catgacttcc tgccgtagtc gcccaatggc tgcatccttg tccgctaccg tgacctccat
     4621 ctgcaaactc tggacagcaa gattcgtttc catttgggag ataatatggg aagaatggat
     4681 ttgcagcccg atcacgagtg tagagataga cgcgatcaca agagttggga cgagaatgac
     4741 agcggctgta gagcattgta gctgcttggg cggttgctgt gcatcccgaa taacaagcag
     4801 ggtcatccgg cgatttaggc ttcctttttt cataatcgct cctttccgga catcgctcct
     4861 atagtgcttg gttactatct attcagctta agaggcaaac atgtcaaaaa aattggagct
     4921 tagtataaaa cgtagatgag gattttgcaa aatcctgaga tatataagga ggcttagaca
     4981 tgctgtggtt gctgttggtt ttaattgttt ttatttttca gaccgggacg atcctgctct
     5041 ttgaatttcg caagccgtcc aaagcggtag cctggctttt tattttgttt tgcttcccgc
     5101 tcattggctt tgtcgtgtac tactttgttg cacaggatta tcagaagcgc aaaatggttc
     5161 gaaaaggggg atcgcagctg tttcgtgagt ttcgcgagcg tctgtgggcg caatccaaag
     5221 tgattgaaca tgtggagcaa atgcataatc ctcatttcaa gcatcaggag cgactgttta
     5281 accagttaat tcgtatgtcg gaaaacccgt tgactggatg taatcgcaca cgtgtgctga
     5341 cgaacggtga agaaaccttc gaagctatgc tgacagcgat ggaacatgca caacatcata
     5401 tccatgtgga gttttacata tttcgggccg acgaaatcgg aagaaagttt caagaggtca
     5461 tgatccgcaa ggcacgtgag ggagtaaagg tacgattcgt tgtggacggt gtaggaagct
     5521 accatttgcc ctattccttt attcgtacct gtagtgaggc aggagtggaa tttcattatt
     5581 ttctacctcc gtttttcgcc acgttggacc gccggattaa ctatcgcaat cacaggaaaa
     5641 tcgtggtagt ggacggcatg atcggatttg tgggggggat taatgtaggc gacgattatc
     5701 tcggaaaata ccccaaagtg ggattttgga gggatacgca tttgcagatt gaaggagata
     5761 gcgtctattt tctgcaaaat gcatttctta gcgactggaa gctggcctca ggggaaaggc
     5821 tgatggatgt gaatttattt cctccacata cctgcaccgg ggatgaggaa gtacagattt
     5881 tgagcagcgg tcccgatcag gtttgggata cgattcagga aatgtgtttt ggagcgctca
     5941 cagttgccaa aaagcggatt tggattacga cgccgtattt tattcccgat ctggggattt
     6001 atgaggcgct caagctggca gcagtcagtg gtgtagatgt gaaaattatt attccctacc
     6061 aatccgattc gaagctggtt catctggcgt ctttatccta tgtgcaagaa ctgctggagg
     6121 caggggtgga gttctaccaa tatcgaaaag gatttattca cgccaaagtg gtgattgtcg
     6181 atgatttact cggctcggtc gggaccgcca atatggacat gcgcagcttt ttctataatt
     6241 ttgagttgac cgctatagtt tttgctaatt cagcgctgga acggctttcg gaagattttg
     6301 tagaggacat ttccaactcc tcacgcatag atttaaacgt gttccgcaga cggcctcgat
     6361 ctcagaaaat agctgaaatt ctaactcgca tgctctctcc actcctttaa aggcggtttt
     6421 cgccgttttt atcgatataa tcccgcttta ttgtgattta tgtgctcttt gctaactttt
     6481 ttgcgcaaaa tcacagtttt atggtatact attcatataa cacaagcgcg gtaaaggaga
     6541 ggggactgcg aatagcagcc cctttttcgg tccaatatac catactgtaa cggggggatt
     6601 tatatatgag tgtagtgagc aaggaagttc aaaatctgtc tgaaatcaca gatgtaaccg
     6661 gagagttgac caagatcagc aaaattccag ctaatccgaa gaacaaagca aaacgcctgt
     6721 ttcagcgtgc ggccatgatt atttttggtg cgacgcttat ggcagtgggc ctcgaaatat
     6781 ttctggttcc taacggcgtt atcgacggag gcgtcacagg tatttccatt atggcctcca
     6841 agattactgg ctatccactc ggtattttcc tgaccctgtt gaaccttcca tttttactta
     6901 tcggatacaa acaaatcggt aaaaccttcg ctttatccac attattcggc attatcgtga
     6961 tgtccatcgg taccgcgtta cttcacaatg taagtgcatt gactcctggc gaaccactat
     7021 tgggtgctat ctttgggggc gtcattctcg gcgttggggt gggtcttgtg attcggtccg
     7081 gcggctcgct ggatggaaca gagatcgtag ctattctcgt cagtgaaaaa actccttttt
     7141 cggtcggtga gatcgtactg tttgttaata tcttcattct gggaagtgca ggttttgtgt
     7201 tcggttggcc gaatgccctg tattccatga ttgcttatta tatcgccatg aaaatgattg
     7261 atattacgat tgaaggtctg gatcagtcca aatcggtctg gattattagt gaaaaatacc
     7321 gtgatattgg ggatgccctg acggatcgtc ttggacgggg cgtaacttat ctggaaggtg
     7381 aaggcggctt tacgggcgaa agcaagaaag tgattttcgt cgtcattacc cgactggagg
     7441 aagcgaagct gaagagcatc gttgaagatt gggacccgca cgctttcgtt gcgatcggta
     7501 acattcacga tgtgaagggc ggacgcttta agaaaaaagg aatacactag cgcaagggga
     7561 caatttctca gcctaatggc tgcggggttc gtcccctttt ttgttcttcc aagcatggat
     7621 caggttcggt gtgccttggt gcgcatatgc ttgaggacgt cttctacggg ctggggagga
     7681 accttgtcga tcaagtcgcc tacctggttt agtcgttcct caatattcag caaatggtag
     7741 tcaagtggtg atacatcttg ccgtacctct tcccatgtta gcggagtgga gaccgtagcg
     7801 ccggggcgtg cccgcggggt ataaggagcg gccagagttt tcccttgata atgctgcaaa
     7861 taatcaaaat agatggctgt tccccgatcc ttctttaacc gttcgagtgt gaacagatgc
     7921 gggtgctttt ctgtcacaaa ctgtccaact aatagcccga tgctgcgaag ttcgtcgaag
     7981 gttatgcctg tacggatcgg aacgataatt tgtacacctg tggccccgga agttttgggg
     8041 acggaatcca aaccaagcga agccagtact tcaccgacaa tagaggctgc ctccataata
     8101 cgtggctcca cctctctgga tggatcaagg tcaatcatcc attcacaggg cagcttgctt
     8161 cccgcttcat gcagagaggg gtggaattcc aacgcagctt gattaccaag ccagagaagt
     8221 tgtggcaatt tgccgagcac gatatattca ataccatcat gcagagcggt ttcaatatag
     8281 tccggccgag gacgtggggc atttttctga taaaaaaaat caccgtgaat cccatgtggc
     8341 cagcggatga cggtcagcag acgatgatgg caatatttga gcaggaaggg agccaatacc
     8401 gcgagcttgc gaagatatag cgccttagtc acgcctgctt caggccacag tggtttatcc
     8461 gggttggtga taggaatttc ctgaccttca atggtaatag tacctttaac agcttgtccc
     8521 ataatgctat cctcctttgg ctaacatgca gcaaaatctt tatttacagg ctgattgttg
     8581 cacttataga tctacatatg gtttaacatg aacgtgaagt gctgaattta tccatcaaag
     8641 ggattgacaa gatacaatat gtatcataaa tttataataa aaatacgata tgtatctatt
     8701 aaagggactt gagcagaggt agaggaggag tttgcttgat tgaaaagcaa ggcggagggc
     8761 tggtatttct gttgagtgtc cctcgaagtg gaagctcgct gcttaccgcc attttgcaaa
     8821 accattcccg cctgtttgcc acacaggaaa tgtggtttct gctcagttta tatgatcttc
     8881 ctcagtcaca ggcacggcca tatggaggaa cagggatact ccggcaattt tttaaaggca
     8941 tggttccctc cgacgtattg gagcaggcct cccgttcgta tgcacttgaa atatataatg
     9001 gtctgcttca aggaactaca gcagatatgc ttatcgacaa atccccgcgt tactatacgg
     9061 tgctggaatt tatagaccgt ttattccctg ctgcccgcag gctgtggctt atccgtaatc
     9121 ctttggccat tgtggcctca ttcaaaaagg tcaatcagct acggaatgga cgttttcaac
     9181 tgctggagga actggggagt ccgcatttta atatgaaaat gacggatatt acggttggtt
     9241 tgttccgtta tgctcattat tttgctacac ctcatccact tgcatacccg cttaggtacg
     9301 aacaactcgt atccaatcca acgatggaga tcgagaagct gtgcagtttt ctggggatca
     9361 agtatgagcc agggatggaa aagtacggag actttgcgga tacgcccaaa tccagtcttt
     9421 tttatagtat gggagcgggt gatccattcg taggagagca tgagcaggcg catcaggatt
     9481 cggtacatag ctggcaacat ttgttgagta aaacggaaat tgagctgtat tgcagaagca
     9541 ttgggtcccg catgtttagg cagcttggtt acgcggaagc gttggagcag gctgagcaga
     9601 tgactggagt ccgctttgaa gatgagccgg atatagagct gctgagtcaa cgtacacaac
     9661 aatttctcca acaaagcggc tttgaatgga aagcagctta tcggatgctg gaagaacaag
     9721 atgcagataa cagagaactc gtgataaatg caacctgtca tgttgcacct caagatccgg
     9781 caaggatgca ggtggaccag atcgtgaacg atcggcggat ccaatcactg gaaaacaggt
     9841 tggcacatag ctatgaggag cggaaccgtc ttatcgctca gctccaaagc tatcaacgcc
     9901 caaatcaaag tctccgatct cgcagcctct ttgcccgtaa gctcgggcgc ttggcgtctg
     9961 tagcgttatc aagcatagga aaagaaaaag ggggaagaac gtgagtgcga ttgccggaat
    10021 ctatagcttt gggcatgagt ccgtaagcac cgaagaaggc gggaaaatga tgcaagccct
    10081 gcgaaaatat cccgctgacc gcgtatgcgc ttggtgcgaa ggctctattt ttttgggttg
    10141 tcatgcccag catgtgaccc cagaatctgt tcatgagcgt cttcccttct atgatgagct
    10201 aagagatttg gcaatcacgg cggatgcgat tattgacaat cgttccgagc tgtttgaacg
    10261 gctgggagtt gagcaggaac ggcggcaaga tatcacggac agcgagctga ttttgctggc
    10321 atatgacaaa tggggagtgg aagcagccag ttatctgata ggtgatttta cctttgtcat
    10381 ttgggatgcc aaggaacatc gattatatgg tgctcgagat atgacaggaa atcgtacgct
    10441 gtacatctac caacatgacc gaggattcgc gtttagcacg gtagtcgctc cacttttggc
    10501 cctgtcctct ctgcgaaaag aactgcatga accgtggcta gccgaatttt tgtccatccg
    10561 tgccatgcag gaatccgtcg atatcggaac gactgcatac aagcatatca accagcttcc
    10621 tcctgcacat tggttcacta tggaggaggg gaagcgaacc cttcataaat atgcatgtct
    10681 ggatgaggta gagccactgc ggctcaaaac agggggcgag tacatagaag ctttccgcga
    10741 ggtgttcaca caggcggtca ctgcccgact acggacgcat cgtgctgtag gggctgcctt
    10801 gagcggaggg ctggattccg gggcggttgc cagctttgcc gcgccatcgc tgcacctgca
    10861 acaaaagccg ctgcatgcct acagctatgt gcctgttcaa gattttacag actggacacc
    10921 gcctacattg ctggcgaacg aacgaagcta tattcagtct acggctcgct atgtaggcaa
    10981 cattcacgaa aattatatgg attttgaggg gaaaagtccg ttttctgaaa ttgatatttg
    11041 gctggaactc atggaagcac cctacaaata ttttgaaaac tccttctgga tcagaggttt
    11101 ttatgaaaaa gcacaggagc acaatgtcgg tgtactgttg accggggcac gaggcaattt
    11161 taccgtatcg tggggccctg cactagacta ttatgcccgg cagtttcgtc gtttgcactg
    11221 gttgcaatcc tttcaggggt tgtggcggta cagcaagctt acgggcaggc gtatgtctca
    11281 tctactccct gtgatgttga aaaaagcgac ttcgcttgaa tctcgttcat ggctgcggcg
    11341 tagcaatcga agtcccgttc cttcactgat ccacccggag tttgccaaac ggatgcatgt
    11401 agaagatatt cctgtattga gcggaacagg ctggatgaaa aacgccgatc agacgagaaa
    11461 agagaaattt tcgaatttgg cgattgctaa caaaaatggt gtggtcgcga ccaaactttc
    11521 actacggtat ggcctgtggg aacgtgatcc gaccggagac agccgagtga ttcgcttttg
    11581 cttatcggtg ccttttgaac agtatgtgca aaacggtcgg gaccgtgccc tcattcgtac
    11641 ggccatgcgt gatcatctac ctgatgatgt tcggttgaac cagcgggtac gcggtgtaca
    11701 gcctgcagat tggttacatc gaatgcttcc ttgctgggat acgtttatgg gagagcttca
    11761 actgatgtgt catgatttac gagccgccga atatctcaat attgagttta ttaagacggc
    11821 tatggcgaaa cttcaccacc cccgccctga gcaggcgtct gatccgaata tacgactact
    11881 aatgcatagc ctgatcgtgt accgttttct ctgtagattg aactgatcga acctatccgg
    11941 tcagacagtt cgccattcgt tggaggggag gtgatgagat gagtaaaaaa gaatggcagg
    12001 aaccgacgat agaggtgctg gatattaacc agactatggc gggtaaaggc tggaaacaga
    12061 ttgactgggt gtctgaccac gatgccgatc ttcataatcc aagctaacac atggttatac
    12121 atgcagccga tgttgggctg gaagcaaaaa aactggtccg ataacgactg aatgaacgag
    12181 aatagcataa tccattggac tcgtattcaa tacaaagccg tctttatttc ttcgggttag
    12241 aggtactgcc caagaaataa agacgggatt tttaaggaca gaggagtgag tcctatcgtg
    12301 catgacagga gtgcaaatgt cagttggacg aaatatatag cctttggact cagaattgcc
    12361 agtgagctga atctgcctga gctgatcctg gcagcaccgg aagcagtaga ggatgtagtc
    12421 attcgacagg ctgatttaac tgcatggagt ggtcagctgg agcaggccaa ttttgtgatg
    12481 ctagatgagc gatttatgtt ccaaatacca ggcacggcca tttatgccgt cagggaaggc
    12541 aaggagatcg aggtaagcat attctccggg gccgatcctg acaccgtgcg gctgtttgtg
    12601 ctgggtacat gcatgggtgt tctgctgatg caaagacgaa tattacctat tcacggaagt
    12661 gcggtcgtca tcggggagag ggcctatgca tttgtgggtg aatcgggtac gggcaaatcg
    12721 acactggctg ctgcttttag gcaggcaggt tatcagatgg ttagtgatga cgtgattgct
    12781 gtaaaagcta cggcttcctc agccatcgtg tatccagctt atccgcagca aaagctgggg
    12841 ttggatagct tgctccaact ggaggcttta cgggagaaca agcatgcacg caaaagaaat
    12901 aacatacggt ccctaactga tggcaattct gtaatgccac aatacagtga tctgcgtatg
    12961 cttgcaggtg agctgaataa atatgctgta cccgccgtag atgaattttt taacgatccg
    13021 ctgcccttag ggggcgtatt cgagcttgtg gcagattctc caatccgtgc gttgatgcgc
    13081 gaaggggagc tagtggcggt tacggaacag cccttgaacg ttctggagtg cttgcataca
    13141 ttactacaac atacatatcg tagggtgatt attccgcgaa tgggtttgag tgaatggtcg
    13201 tttgatacag cggctaggat ggctcgtaaa gtagagggct ggcggctgct gagggatagt
    13261 tccgtcttta ctgcatccga ggttgtacaa cgggtacttg atatcattcg taaggaggaa
    13321 aagagttatg gcagccacta attcagctaa ggaccattat cgcgtcattt acggtgaaga
    13381 ggtctatgtc agtgatatgg acggagaaaa agtgatgatg agcattaaca ctggtaaata
    13441 ttataactta ggcttcacag gaggacgaat ctgggaactg gcagaatccg gtccttcact
    13501 tggcgatatc gtaactgtcc tgacgaatga atatgaggtg gacgaggaac agtgcagaca
    13561 gcaggtacat acctttgtgg ctgagttgga gcgggaagga ctgttaaagc ttctacggga
    13621 gtcggtataa catgcggata caacggcttc ttctcctgtc tccagaggtc aggaaattgt
    13681 tgccggaagc ctggctggag ctgggatggg cgaggctgcg ccagcgtcgt tcttttgggg
    13741 attactcaag ggtttggggc atatgtatgg aagaaactcc atggcagtgt gatgtcaggc
    13801 aggagaagtc cattcagcag atttcgcacg ctgtggagct ggcaagccgt tatactcctt
    13861 ggcgcagtag ttgtcttgta caagccgctg cggcgatgac gttgctgggg cgcagaaaac
    13921 tggactgcac gctgtatctg ggcacagcca aaaatgccgc tggacgcttg gccgcacatg
    13981 catgggtacg tagcggaccg atttatgtta cggggaaacg ggagatggaa gcatttacgg
    14041 tggtggggat attcgggaga cgtgctgtga tggctacaaa tacaaaaaaa atgaaagata
    14101 aaggcagttc tttgctttaa tgcgatgaga caagaaggag aagaatgcat gcccaccaag
    14161 tctgttttgg aacttgcgaa ttggaatgag gatcaagaat taacgttgtt actctctcta
    14221 ttggggaaag acgtttctca ttggcaggat aagactgctg ctacccagct gcgtgagatg
    14281 gattgggtcc gctttttacg tctgaccgag caccatcgag tggtacctac ggtgtatctc
    14341 caactgaaaa cattgaatca tccgttcatt cccgcagaat tgttgcgaaa ccttcaggcg
    14401 cagtatcatc gaaacacgct tcgcatgctc catcttcaag cagaagccga gcgtctgacc
    14461 aggctgctca tagttaatgg aattcgtgtg cttatgttga agggtcctgc tctggcgcag
    14521 cagttgtacg gggatgtttc tctgcgtacc tccaaggata tagatttact cattgcccct
    14581 gacgatatgg atgaggctga gcattggatg aaggaagccg gatatgcgtc caagagcgga
    14641 gaagtgcgtg tccttggtag ttggaaatgg aaggaccatc atgcatccta cctccatccc
    14701 caaaaacggg tagagattga gctgcattgg cggcttcacc cggatggggg tggggaaccc
    14761 tcttttgacg agctgtggaa ctgccggaaa atgggcaaag ctgcaggaac cagtcggcag
    14821 gtaccgttgg gacctgccga caacaggact gtgatgacgt cctgtatgta tacgcttggc
    14881 agcgagcatc aatttctgta cttgagcgcg catggtgcgc gtcacggctg gttcaggctg
    14941 cgctggctgg ttgacatcga caggcttgcg gtatgtgctg tcgattggga ggcgctactg
    15001 ccgatgatgc gccgctacgg gggcctgcct gctggcgggc aggcttgggc actcgccgct
    15061 gcgctgttgg gtacgccgat accggagtcg atgcgtccgg tatcggctac ccggcaggcg
    15121 cacaggctcg cgctgagcgc gctggccttc atgcaggcca gcgttcccgc accgtacccg
    15181 attgcccacg ggtcgggtac aggtaggctt gctccatctg agctgctgca tagcagagct
    15241 ttggcggagc aagcggaagc cgcccctccg gatggcggtg cttcagtatg cggtacctgt
    15301 ggcgaagcag ccatgcttgc caccagtggc gttactagca tcacggaaga tgccagtaac
    15361 gacgaccata gcccgatgag cactgctacc cgttgtgccc ccattactcc agctgtcgcc
    15421 tccagccaag tcatgaccag aaacacggcg gctgcccatc agccggtcag ccgcacttac
    15481 ttgctttcct taaaagagcc aagacacaga ctatggtacc tcatcagccg tttgtttcct
    15541 tctacggggg attcggccgt ttttccactg cctcgccagc tgcatttttt gtatatccct
    15601 ttacgtccat ttctttggct gaagcggcga ttttcaaagc actgactcga tagaggattt
    15661 tgcaaaaatc caataagcga ctttcaatga acaatatata gatcgaaatg gtctagttcg
    15721 tctatatatt gcactttgga gcgactggaa tcgaattttt caaaatcctg gataaggagt
    15781 gtgcattatg gttcacctgc gattatatat gacaaagctg tatagcgtga acggcggtgc
    15841 gttatttctc aatattggat gtatgatcat tgtcagcctg ctggagggtt ttggcattta
    15901 tatgcttgtt cctatgctgg cggctatcgg cgtatttgtt ggtcattcag ggatgccatt
    15961 tctgtctggt ggattggaac attttttgcc gttcattcct aaaagctggc tgttgccggg
    16021 gatgttgatg gtttttatag tgctgcttac agggcaggct ttgcttcagc gttaccaatc
    16081 catcctgaat tcgcggattc agcagcgttt tatgcgctct ttgcgaatag acgtgtacac
    16141 ttcctttatg aaggcgcagt gggcatttta tttgcgtcag cgtaaatctg attttagcca
    16201 tgtgatgacg accgagctgg cgcgtgtcag tcagggaacg aatttgcttc ttcaactgac
    16261 tactgctgtc atgtttacga tgatccagat tgcgttggct ttttggttat ccccctcttt
    16321 aaccgggctg gtatttctga gtggattggg gctgtttgtc gtgttccgcc gctccattcg
    16381 aaatgccaaa caattaggtg atcgtaccac tgagctgtcg caggtttatt ttgctgggat
    16441 tacggatcac atgaacggca tgaaagatat taaaagcaat ctgttggaag cggcgaatat
    16501 ccattggttt cgctccctga cacaacgcat ggaggataat acgacccaat ttgtccggca
    16561 aaatgcgacc acacagtttt ttcatcgtac agcggcagct gtttttgtcg cttgtgtcat
    16621 atttacatcg ctgcagtggc tgcatgttac tcctgaaaaa ctgattgtgc tgattcttat
    16681 attttcacgc ttatggcccc gatttgctct tattcaagcg agtctggaat acatcatgtc
    16741 tatgatctcc gcttttgaga gtgtcaccaa ggtgcaacag gagtgcgaag ctttcacaga
    16801 tccgtcattg attgtatctg catctgtacg gcaacccctg tcccttcgtc atgggatcga
    16861 atgcagccat ctggattatc gctacgatgg tgcagcagag tctgcgctgc gtcaaattaa
    16921 cttgttcata cccgctcggg gaatgacagc cattgtaggg aaatcgggag caggtaaaag
    16981 tacaatggtc gatgtcctga tgggtttttt acgtccaact ggggggcaga ttacaataga
    17041 cgggcttgtt ctggacgacg aattgttgct ccagtggcgg cagtcgtttg gctacgtgtc
    17101 acaagaccca tttttatttc acgcgactgt ccgcgaaaat ttgatgctgg cagataagga
    17161 tgctagtgag cagcagctat gggaggcgtt acattttgcc gccgcagaca actttgtatc
    17221 cagattgccc gaagggctgg acacagtaat tggagatcgc gggattcgtc tgtctggagg
    17281 agaacgtcaa cggctagtat tagcacgggc tgtcttgcat catccttcgg tacttatact
    17341 agatgaagcg acaagtgcgc tggatggtga gcatgaagcc gcaattcagg cagcactgga
    17401 acggatgaaa ggtcaaatga cgttgatcgt cattgctcac cgcctgtcaa ccatcagaca
    17461 tgcggatcaa attgtcgtac tggatcaagg cgaggtcata cagcagggga actaccacca
    17521 actggaacaa gaggagcggg gggcgttcag tcagctacta tcgtatcaaa gcagtgtcac
    17581 cgccacccct taaccagact tttctgtaac tcagcttaag tttctttacg tttggcagtg
    17641 cttcttttct ttttgactgg agtcggagag atgttctcgc ctgcaacagc ctgctgtgct
    17701 gttggggccg ctggtttacg cgcagggcgt tttttcgcag cagggccggg atcggtaacg
    17761 acaggttgca ctgcctcgat gctggcctga agggcggcca ttaaatctac tacattggtc
    17821 tgaggctgtg ttggggcgat tcgcacctct tcaccagcca ctttatgttg aatgagatcc
    17881 agcagacgct cgcggtactg atccgtatac tttgctgcat caaaaggtgt agatagctgc
    17941 tcgattagca tttttgccat ggtcagctcc ttctctttaa cctcctcctg ccccggtaag
    18001 ttaggcactt gagcaatggg gcgaatttca tcggggtaaa acatcgtctc caccgccaaa
    18061 cattcatcca acacccgaat agccgccagg ctgcttttag agcggatgga gatttgggca
    18121 atcccgattt ttccggtatc cttcatcgca ttcatgagca gcttatacgc attggagcca
    18181 gcttgatctg gggacagata atacgttttc tgaaagtaaa tcggatcaat ttcctgtaaa
    18241 tccacaaaat ctaaaataac aatattttta tccgcttgtc cgctaacttg ctccagctcc
    18301 tccttgtcga acatgacaaa ttttcctttt tcatattcgt atccttttcc aatttcctcc
    18361 cattcgacct ccttgtcaca aacgggacac tttcgtacat agctaagtgg gcttccacac
    18421 tccttgtgaa tataacgcat ggaaatgtcc ttatcctcag tcgcagaaaa cattttaacg
    18481 ggcacatgaa ccagcccaaa gctgatcgcg cctttccaga ccgtatgcat accgccgctc
    18541 ctccttttct ttaatccgca ttttgtatcc ttcgattcca acgctcggct gtgagcatat
    18601 ccatttttca cttagatttt tcacttagta tgcttcggag aaaggaatgt atgaggtgta
    18661 aagaaaagag caagccaact aatctgctat tctgaggtgt gactacatcg cataacacaa
    18721 tgatataaaa ttgttaagtt acattagtta tattaagata agggataacc aacgattttg
    18781 acattttaaa gaaaggagtg ttcatgtcat gaagaaaaga tcattaaact ttatatcttt
    18841 tggatatgga tactctactg ctgttttttt ctaaaatcat ttttattggt ggagtctgcc
    18901 taaaaatggt tagaagaaac ggtagaaaaa tttaaaaatg acgaggtcga tttcggctac
    18961 cttactgctc taggattgcc tgaaataaaa attgaaattg aaatttgggc agctaaagca
    19021 taaaaataat acgcacctca tttatgggat ggaatcatag atagccccgg tcttcgtgag
    19081 aagctggggc tgttttatgt ttaaattcac gaaaaatgta catccgtcgt cgcaagcaaa
    19141 cgcactaaac gattaccgag catcgcatag tgatgagcta tccgcatctg catccttcga
    19201 ttccaacgcc ttggctgtga gcaaatcatt tttatgtttc gtacaaagga tttgtatgag
    19261 ttgtgaatga agactgcgaa ttgcttccgc gtgcgcatgg ttacagcaag tttggtgcat
    19321 agtaaggcat atccgattca aaagggggta cacaatttat gtccggaaaa tcctatcctc
    19381 agcaaatcag gcatcgtgtg ggtcaaagcc aaatcgcctt tcggggccca gctggaggcg
    19441 aacaggatgc attgccgccc gagtttgctc tttcacatgg aatccgtccg ccttttcccg
    19501 tagctgtggc tcatgtggat ttggaggctg tagtttcaac ttcgccttct catagcatcc
    19561 cttcattaga cgttgaacgg attatagatg aagactaggt gaactatatt tctgaatgaa
    19621 tgcacacaac aacaaacagg aggggaagaa taacatgaac gtggaacgag caaaagctat
    19681 ttatgattca tccgaaaata ttgccgtaca attggatggt aaaccgatct ggattgagca
    19741 tgtagaccaa gcaaacggta tggcaacggt acagataggt agcagacccg gcaataccca
    19801 aaccgtccgt gtggatcgtc tggaagaaca atagaagagg ggcaccaaac cagatttttc
    19861 ccatagtatg gggtataact ttagaaagat cttggacagc tgtaggcttt catcgtagaa
    19921 tgctacttga atgatcccgc ttcaacccta aaaggctcgc aattgctcaa tgagcaatta
    19981 gcgaacctta tttgtaataa tgaatacagt cgagggaaca agttaaacgc cagacaagtt
    20041 aatttgaagg tggagttggt tcctttacat gactttatac tgcaatggcc tttaaatgtg
    20101 gtgaaatcat cagtttagcc tcagttgcca attgaacgtc ttccaccgat aaacccggcg
    20161 caatttcctt cagcatcagc ccactacctg gaataacatc gatgacagcc ttttcggtta
    20221 cgatggtctt tacaacattt acagcggtca ggggtagttt acattgttcc agtattttcg
    20281 gcgctccatt tttgttcaca tgctccatgg ctacaatcac tctcttggct ccgaccacca
    20341 aatccatggc tccccccatg cccggaacct ttttccctgg gatcatccag cttgcaaggt
    20401 tgcctttctc atcgacctcc agggcgccca acacggtgat atccacatgc cctccacgga
    20461 tgatagaaaa tgaaagcgaa ctgtcgaaaa agcaagctcc ttccatagtt gtaacatagt
    20521 ttccgcctga atcgatacaa tcgagtcttt ctttcccctg agtcgctttt gggcctacac
    20581 cgaggattcc gttctcagcc tgcagcataa tatgaatgtt ttcggggata tagtctacca
    20641 ccattgtagg cattccaaca ccaaggttga caacttcgcc atttttaaat tcctgggcta
    20701 ttcttcgagc aatgaattct ctgttattca tgcgttttca cccaccttta caattgcgtc
    20761 gacaaatatt ccgggaacgt tgacatgatt ggggtcaatt tctcccgtct ttacgtattc
    20821 gtctgtctga gcaactacat actctgccgc tgtagccatt accaaattga agttacgtga
    20881 agagccgttg atgacaagat ttcccgcttc atcagcctta tgagctctga ttagcgccac
    20941 atccgctttg agcggcagtt cgagcaaata ttctctcccg tcaatttgga ttttcttttt
    21001 tccttcctct acaatggtgc ctacacctac aggcgttaaa acaccgccca agcctgctcc
    21061 tcctgcacgt attttttcag cgagcgtacc ttgcgggaag agttgaacct ccgcttcttt
    21121 cgtcatcagg agccttcccg tttccggatt agagccaata taggatgcaa aaatccgctt
    21181 tactctgccg ctttttacaa gcttatagat agataattcc ggtgtgcctg tatcattgga
    21241 tataatcgta agattgctgg cgggattggt gtcgacaagc gcacgtacaa gttcctccgg
    21301 aaagcctcct gccagaaaac ctccgaccat caccgtgtct ccgtctttga tctgcttaac
    21361 tgcttcttca gcggagatta ctttgttatt catggttcct tctccttata tatatatttt
    21421 taggaaagca actttattgg agataatcat agaggactct tccatatgga agcgttaaat
    21481 cggcaataaa atgttttccg ccaatataag cttttaccgg caaatctgcc acaggagcgt
    21541 tgacatgggg aatcaggctt aacctcgcag gccctgacca ggcgccttta accgtaatgt
    21601 tttcgagatt atacgctacc aactgagcaa ttttaggggt accgtcaaca tcaggaatta
    21661 atttcaaatt aacttgcgtt tttgcgatgg ctttagccgt ttccttttca tcaagaatgt
    21721 tatatttgaa aggcatggtt cccgtggcca ccaggacgtt gttgtaatgc aatgtacccg
    21781 tcagcgtttc cgtctcctca acgatcaagc gaggcttcgc ccattttttc ggaaatcccc
    21841 agatttcacg tcctcccaga atagcaggcg cgttatccaa atacatttgg gcaacaaaat
    21901 tacagggttc tccatgaaaa gtacacggaa tgacaatacc gctttcctca tagcttccta
    21961 acccggatga atcgggcatc ttgatccatt cataggaaac ggtattgctt ccatccggct
    22021 gaagaggttc cgggaccgcc tgtctaatcg cagcgggatc ggattcatag gtaatgatga
    22081 aaaattcccg gttgatgaag cgacatggcg ggcgcccata actgccgctg gccgcaggca
    22141 tggattggag tgaaagtaca tctttttgat tcatagcgat ctcccttcct tttaagagat
    22201 agttctaaaa gtcatcctga actcgcactt taaatgagtg cattttcaac tagcatcgct
    22261 attcccattc ccgttccgat gcataacgag gcgatgccgt aacgtgaaga tcttcgcacc
    22321 atttcatgaa ccagcgtaac caatacccta gcaccgcttg caccgacagg atgcccgatc
    22381 gcgatcgcgc cgccattgac attcaccttc tcaggattga ttccaagctc tttcaatacc
    22441 gctagtgctt gtgcggcgaa cgcttcatta atttcaaaaa gatcgatgtc atcaatagac
    22501 attccctgtt gcttcagaag tgacgaaatg gccttcaccg gtcccattcc catatatgca
    22561 gggtcaacgc caacaagtga ataacccttg atatatgcca acggctttaa cgcatgttcc
    22621 ttacatttgt cttccgacac tacaagcata gccgccgcgc catcattgat tcctgaagca
    22681 tttccggcgg taactgttcc gttctcctta aaggcaggtt ttaattgaga aagtttttct
    22741 ttcgttgtat ttcctcttat gtgttcgtcc tccgtgaaag atatagtttc ttttttattt
    22801 ttaatcatga ctggaacaat ctgctcttca aaaagcttct tgtttttagc ttctacggcc
    22861 tttatctggc tttgatagga aaattcatcc tgctcaagtc ttgaaattcc atattcctct
    22921 gcaacatttt ctgcggtaat tcccatatgg taatggttga tcgggcacgt aagaccgtcg
    22981 gccaccaggg agtctaccaa ctcaccgttg ccaagtttgt agccgtttct tgcattcctt
    23041 agcaggtaag gggcattcga catgctctcc atgcctccgg ccaagacgat gttgccttgt
    23101 tccgccaata ttgaattgta ggctaaagca acggcatgga gtcctgaacc gcaaaccgtg
    23161 tttatcgttg tttcgggtac atcaataggg ataccggctt ttagtgccgc ctgtctggca
    23221 ggattttggc cattgcccgc ctgaagaaca tttcccaaat aaatttgatc aatcaaagaa
    23281 ggctctaatt tactttgctg aaggcatgct gtcatcacag ttgctcccag ttcaggagcg
    23341 cttagaggcg caagggtttt gttaaaagag ccgaccgctg ttctcaacgg gcttactaaa
    23401 gctacttttt tcattaaaaa ctcacattcc tttcgttgtg ttcaagacac aatacatcca
    23461 tgattgcact tcaattcgta atttccgttc ttaacctacg agatgtagcg actgcaagat
    23521 acatttgctt gcgggcatat catggtgcct aagacagtga gtgtgagggt tcgatcgcct
    23581 tctctcgttg gaaattaaaa ccagtttcat catagttcta atgcagattt tgctcaatgt
    23641 tcaaaaatat acacatatct atgtacagat gtttatagag ccatataggc cacaataatt
    23701 aggctattct aatgttttct gttaatttct taatttttct gaaaatcatg atcataaatt
    23761 gaattttctg ttaaaaatga aagttacaat ccatacgtga aaaagttttc ctcgcaaata
    23821 tcatctaact catcgctggg aaataaaaaa aagcctccag aatgttctga agacggattt
    23881 gcctttcaat attcataatc ttcgttatat tgtgccagct tgcttcttgt taacggtgtc
    23941 acttgaaagg gcgatttttt cgtatgaaca ataaaagaag ccgacttgct tgaaagcaat
    24001 cggcttggaa cataaaactt caacaactca cgaaaaatgt acatccgctg tcgcgagtaa
    24061 acgcacaaaa cgattgccaa gcatcccatt atgatgcgct acaatttgtt cactgctcag
//
