LOCUS       NZ_CP017968            21455 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Paenibacillus polymyxa strain YC0573 chromosome, complete genome.
ACCESSION   NZ_CP017968
VERSION     NZ_CP017968.3
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 6126117)
  AUTHORS   Liu,H., Hou,Q., Liu,K., Wang,C., Ding,Y. and Du,B.
  TITLE     Complete Genome Sequence of Paenibacillus polymyxa YC0573, a Plant
            Growth Promoting Rhizobacterium Isolated from Rhizosphere of Tobacco
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6126117)
  AUTHORS   Liu,H., Hou,Q., Liu,K., Wang,C., Ding,Y. and Du,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2018) Department of Microbiology, Shandong
            Agricultural University, No. 61 Daizong Street, Taian, Shandong
            271018, China
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 6126117)
  AUTHORS   Liu,H., Hou,Q., Liu,K., Wang,C., Ding,Y. and Du,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-NOV-2016) Department of Microbiology, Shandong
            Agricultural University, No. 61 Daizong Street, Taian, Shandong
            271018, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: canu v. 1.3
            Genome Coverage                   :: 140.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 04:02:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,505
            CDSs (total)                      :: 5,362
            Genes (coding)                    :: 5,219
            CDSs (with protein)               :: 5,219
            Genes (RNA)                       :: 143
            rRNAs                             :: 13, 12, 12 (5S, 16S, 23S)
            complete rRNAs                    :: 13, 12, 12 (5S, 16S, 23S)
            tRNAs                             :: 102
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 98 of 143
            Pseudo Genes (incomplete)         :: 53 of 143
            Pseudo Genes (internal stop)      :: 19 of 143
            Pseudo Genes (multiple problems)  :: 23 of 143
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:01:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 388667
            Orig. end                         :: 410122
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017968.3.
            On Feb 23, 2018 this sequence version replaced NZ_CP017968.2.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21455
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="2"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21455
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21455
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11455](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11455
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    367..379
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.49"
                     /tool="antismash"
     misc_feature    711..726
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.42"
                     /tool="antismash"
     gene            complement(1185..3347)
                     /locus_tag="PPYC2_RS01670"
                     /old_locus_tag="PPYC2_25030"
     CDS             complement(1185..3347)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308372.1"
                     /locus_tag="PPYC2_RS01670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_25030"
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="WP_081365924.1"
                     /transl_table=11
                     /translation="MEQHLNSYLENMTLEEKVDQLLQLVGAFFEEAGTDSQITGPMASL
                     GITEKNVHNVGSVLGIAGAKEAIRVQQAHLSKNRLGIPLLIMADIVHGFKTIFPIPLAI
                     GCSWDMQLAEESATIAAREAAVSGVHVTFAPMVDLVRDPRWGRVMESTGEDPYLNSEFA
                     RAFVRGFQGKDLTNDTDRVAACVKHFAAYGAGEGGRDYNTVDVSAWQLREYYLPSYKAA
                     LDEGCEMVMTSFNTVEGVAATGNKRLMRDLLRDEWGFDGVLISDWAAIKELIPHGIAED
                     EREAAKKALLAGVDIEMMTSCYNGHLPELVRSGQLDEALIDEAVMRILKLKQKLGLFEN
                     PLRGADPEREREVVFCEAHRTVAKELAIKSCVLLKNDSVLPLNRNQHIALIGPFAESGD
                     ILGSWSWSGSQEEAIRVVDGFQSKISSSLLTVAAGCSIDDITEEQYAEALQAASQAEVI
                     VLALGERSDMSGEAGSRSNIRLPQAQLELVKRLKTLNKPMVAVLFNGRPLDLHGVIEEA
                     DAVLEAWFPGGEGGAAIADLLYGDAEPTGRLTMSFPQSVGQVPVYYNHFNTGRPQLDPN
                     TKERYVSQYLDVPNEPLFPFGYGLSYTDVAYDSVQLSGDTLIPGQELTVKVQVTNTGTR
                     PVEETVQFYVRDISGDTVRPMKELKDFCKVLLAPGESREVEFALTEPQLRYHHADLSFS
                     SDSGEFAVFTGPNSRDTSESRFRLVK"
     misc_feature    complement(3408..3421)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.18"
                     /tool="antismash"
     gene            3950..5203
                     /locus_tag="PPYC2_RS01680"
                     /old_locus_tag="PPYC2_25020"
     CDS             3950..5203
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017425689.1"
                     /locus_tag="PPYC2_RS01680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_25020"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_034094959.1"
                     /transl_table=11
                     /translation="MMKRTLGIILASTLLLGGALVGCSSKDDSSGKDANGKTTITMWGM
                     GAEGKLLPEIVKDFEKENPDIHVDVQALPWDNAHDKLLTAVASKSGPDVVQLGTSWVPE
                     LASAGALTDITPYISKYPELESKNFFEGAVGTTKFEGKPVGVPWYTETRVLFYRSDLLK
                     QVGYNEAPKTWEELSDAAQKLAARGKGKYGISFSAKEQSMGFMFALQNGSKLVDEQGNP
                     LFNQPPFVDAVKYLNTFFQNGSNAVDIGIDSVQGLQGDGIVPMFISGPFMIKEIKSKAP
                     ELEGKWNIAELPGKVNNLSVLGGANLSIMQFSKHPEESAKFMAYMSKPETQLKWMELSS
                     NLPAATKSWEDAKLKSDPMLQTIRKQLDHSAALPQLAAWEEVSQQFIKSFERVYRGQAD
                     VQKEMDDFNQQAASIMKK"
     gene            5240..6124
                     /locus_tag="PPYC2_RS01685"
                     /old_locus_tag="PPYC2_25015"
     CDS             5240..6124
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014279338.1"
                     /locus_tag="PPYC2_RS01685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_25015"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_028541958.1"
                     /transl_table=11
                     /translation="MKGSSQKLAPYLFIGPSIILLTLFSLLPILLALVISFTDMDLSGL
                     VNYDSIRFIGLENYTNVLMDPSFIKSLGNTLFFVIIGVPLVLIFSLSIAILINMGKSRA
                     FKVFRVVFYLPSVTNVVAVAVVWSYLYNPTLGLFNYVLGLMNLGPVPWLTDPTVAKVSL
                     IVLAVWRGIGLNMIIFIAAIKGIPGSYYEAAQLDGANTWQQIRYITLPQLRYAIFFVSI
                     TTMIGWLQFFEEPFVMTKGKPLDGTLTASLFIYNNGFQFSKFGYAAAGSFILFFAIIAV
                     TLIQFRLQNKAES"
     gene            6143..6997
                     /locus_tag="PPYC2_RS01690"
                     /old_locus_tag="PPYC2_25010"
     CDS             6143..6997
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308375.1"
                     /locus_tag="PPYC2_RS01690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_25010"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_071559705.1"
                     /transl_table=11
                     /translation="MKTAVQQARANTRSGEKTFQWFVAILLTVGGLLMVLPFAWMILSS
                     FKTESEVTKIPPTIWPQHFTLDNFKLLFDSMAFGTYLTNTLIIVLASFFGLFLNAMAGY
                     GFAKFQFKGKGFLFYLVLATMMIPGQVTMIPVYLILNQMGLTNSMLGIVLPGLVGAFAI
                     FLFRQFMSDIPEELLEATRLDGAGEFRTFLQIVLPISTPILAVQAILTFIGGWNSFLWP
                     LIIANDEKLYTLSVGLSLLKGQNESQFALQMAGSTFMVVPIMIIFIVFQKYIIENYTIS
                     GIK"
     gene            complement(7094..7681)
                     /locus_tag="PPYC2_RS01695"
                     /old_locus_tag="PPYC2_25005"
     CDS             complement(7094..7681)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016430.4"
                     /locus_tag="PPYC2_RS01695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_25005"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_053324443.1"
                     /transl_table=11
                     /translation="MPTTMVIDCCKEDQCRGSSRCFYRKICELYLSEVYRFCMHLIKNQ
                     SCFTFMAEECTQDTFVAARQQLVKLKHHPNVKGWLYLTAKNLIYKSFRCYYTQKKHETT
                     LECEKICSFSNSVEEEWENRRLGDVDTVIVNILMQLSNIEYTLYEDYFCRQLAVPLLAT
                     KYNISVTATTTRIYRLKRKLRTLSHQYCLTHI"
     misc_feature    complement(7705..7714)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     gene            7897..9639
                     /locus_tag="PPYC2_RS01700"
                     /old_locus_tag="PPYC2_25000"
     CDS             7897..9639
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308379.1"
                     /locus_tag="PPYC2_RS01700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_25000"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_053324444.1"
                     /transl_table=11
                     /translation="MKESIVYKRLAATFRPYLKTVTIILICLILSAGLNILLPLTSKII
                     VDQGLLEGNMQAVILYTSAAFLIVCLDKLLNVCKETFRAGLSAQVTFSLFEKAYLHLTR
                     VRMSYFNRTNEAELLNQIGTDVGNVSRITDSGVFFVIMQAFSMIGGLCGLLLINWKMTV
                     IVLCFLPIKYVVVKYFAKRRKKLVGDLIEGSSDFAQWFGESVGGMKEQRMFGLIPHKHQ
                     QFSSKQRRIVESERKLSLLDAWNIASESILIQLLMMFLYVVGANLIFRLQLTVGGIFAF
                     VSYSAYVTTPVFAILNIGYMLAEVVPSAIRYYQFLDWAEEETSNSVTPASLLTEPPFED
                     HIAFHNVSFSYTKDEPVLPHVSFRIARGEKVAIIGANGAGKSTLLDLIMRFSQPDQGII
                     TYDGIDIQSYEIDEYRSQIALVSQQVYLFDTTIFGNIRIGTEVTNDAIEAIIAEVGLEE
                     LVQNSADDFPIGSNGSRLSGGQRQKIAMARALIREAPLFILDEVTSNLDTAARLNVQQL
                     LKTRLREKTVIIVTHRSEILAHVDRVILLENGEPAQIGSHSHFMTCHAEYRGWVLGEEE
                     VPIK"
     gene            9744..9929
                     /locus_tag="PPYC2_RS01705"
                     /old_locus_tag="PPYC2_26700"
     CDS             9744..9929
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04065.1"
                     /locus_tag="PPYC2_RS01705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_26700"
                     /product="CLI_3235 family bacteriocin precursor"
                     /protein_id="WP_071559456.1"
                     /transl_table=11
                     /translation="MRKLVKRSTNVGDTIEAFGCGCSCYCPCSCYCAGSLTRSSNTQRE
                     SDGSYRRDNGTGIGNY"
     aSDomain        10001..10378
                     /aSDomain="Other_Sactipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a sactipeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_PPYC2_RS01710_Other_Sactipeptide_rSAM
                     _RRE.1"
                     /evalue="6.90E-15"
                     /identifier="RREFam021.1"
                     /label="PPYC2_RS01710"
                     /locus_tag="PPYC2_RS01710"
                     /protein_end="126"
                     /protein_start="0"
                     /score="46.1"
                     /tool="antismash"
                     /translation="MNMCQPFIYTFQTRLHHYVYDVNTNLILRIKEEAYHFLNSHSSFD
                     LDQMEATPELQHYIRDLLDNGFLSSQRPQIMNHPKTKHLEHMLQHQLKTLTLQVTQNCN
                     LRCSYCVYSGGYDNRGHTSLMM"
     gene            10001..11455
                     /gene="ccpM"
                     /locus_tag="PPYC2_RS01710"
                     /old_locus_tag="PPYC2_24995"
     CDS             10001..11455
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="ccpM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308381.1"
                     /locus_tag="PPYC2_RS01710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_24995"
                     /product="Cys-rich peptide radical SAM maturase CcpM"
                     /protein_id="WP_028541961.1"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     1.3e-12, bitscore: 46.1, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 4.2e-54, bitscore:
                     182.2, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.1e-12, bitscore: 47.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6.3e-10, bitscore: 37.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMCQPFIYTFQTRLHHYVYDVNTNLILRIKEEAYHFLNSHSSFD
                     LDQMEATPELQHYIRDLLDNGFLSSQRPQIMNHPKTKHLEHMLQHQLKTLTLQVTQNCN
                     LRCSYCVYSGGYDNRGHTSLMMDFETARKCIDFVIDRSVDSDRLDFGFYGGEPLINFPL
                     VKKCVEYIKEQVAYRDVGFHLTTNGTLLNDDILAFLDEHRFVLTISLDGDQENHDRNRR
                     FAVNGRGTFDTIIANVDKIKRNYPDLFEWINFNVVLDTRNDFGCINDFYTNYETFESLY
                     SVRSSYINDAYVKDEILYRNEFIEQRGYEVVKMMLSKFGRVDENHVSKLIKDYYIQMYF
                     RMFHYRKPSAGMPIEAHHGGPCVPGVQRLFADVHGNLYPCERVSEQSEVVQIGKVDTGF
                     EVDKISQILNVGTITEDACKNCWNFRFCTLCVAVADDLHTLSKEKKLSHCSVVKNDIRH
                     TLLDYCMMNELGYDFSEDTILDFEKA"
     gene            11467..12591
                     /locus_tag="PPYC2_RS01715"
                     /old_locus_tag="PPYC2_24990"
     CDS             11467..12591
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308382.1"
                     /locus_tag="PPYC2_RS01715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_24990"
                     /product="TIGR04066 family peptide maturation system
                     protein"
                     /protein_id="WP_071559455.1"
                     /transl_table=11
                     /translation="MTNKLIIFPFDYETIALVRNLNLLGSYEEVVLISFQGSGMIGKDA
                     CVTDKGEVTGFIVKPESCLEQEMERCDAILLVKSNFKLDVAEVYLPVIQKAGQLGKKVM
                     CNFTLPDSCMEFIEPCEEQDDKLILKNTFDVRTKDILPPDPGSVIHDFFTPVLFVLGLN
                     ERTHKLNLQLNLRQKLEAQGYRVSQITSNGCGELIGAHSFPQFMFESGMTETQKIIMFN
                     RYLKKIEQSEKPDLILVGIPGGIVPFNNTFTNYFGVTSFLVSRAVRADGLICCLHYDEY
                     NIKYLEHVKQYMENRFSSSLLGYAICNNVFDSYSSSTVNMQYASVDHRFVEEKKQEFSN
                     YSVPVLHLSNDEDMNRLTQDILHYFSVDHHVVQL"
     gene            12605..12880
                     /locus_tag="PPYC2_RS01720"
                     /old_locus_tag="PPYC2_24985"
     CDS             12605..12880
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308383.1"
                     /locus_tag="PPYC2_RS01720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_24985"
                     /product="peptide maturation system acyl carrier-related
                     protein"
                     /protein_id="WP_023986627.1"
                     /transl_table=11
                     /translation="MNFTQDVTGTGMKLENIFWKLFKIKAGEINKEATLLGPDMGLFPR
                     DLVYLLFEVEKSFAILIPEERIVGGGLLTYNSLYETIKDCLTVEKE"
     misc_feature    complement(12889..12903)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.52"
                     /tool="antismash"
     gene            13004..13786
                     /locus_tag="PPYC2_RS01725"
                     /old_locus_tag="PPYC2_24980"
     CDS             13004..13786
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308384.1"
                     /locus_tag="PPYC2_RS01725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_24980"
                     /product="hypothetical protein"
                     /protein_id="WP_053324446.1"
                     /transl_table=11
                     /translation="MNVSFTSSHQSPFRTADNNRLELRHSLSAQAERKGIGKPQNKVIQ
                     QLTEQKQSLMERRSDYLSNALKRGLGPEAVKAEMEEIDKQIQQIDENIQKQSLEEQKKA
                     LGMDEESKKEAQKGKKEEYTPKTAEEQQQRLITYTMHSIVSANNELKSAKIAKTAQITL
                     GSEAKGWENANPAKSAALREKAEGLNGEIMEIAANINERISEAVNNEPMITDRVEPKDE
                     QEANAEAGRVWTEQELNAYLDSAKDGAKTAGTKVNIAV"
     gene            13935..15521
                     /locus_tag="PPYC2_RS01730"
                     /old_locus_tag="PPYC2_24975"
     CDS             13935..15521
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308385.1"
                     /locus_tag="PPYC2_RS01730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_24975"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_053324447.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 2.9e-11, bitscore:
                     41.5, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGKIHVAIIDDGVNAGFLNTQLLYNVEIAHGDVEDGRTLNHGTI
                     CAAIVQTYFPDAIISSVKIMNHRKGNAAQLCAALDWCVKHGVQVANISLGSINYRDRGM
                     LREAVNNAAMAGLIMVCAAQNGGLLTYPASFANVIGVRCDHSGILTAGQYTYDAEKAFS
                     SGIDFTAFAKHELVGAAGEAVQCPNSNSYATPLITAHICKVLQQSMPVPSIEQLKHILH
                     KYSYLPIQDTIIPVMRYGHPDWIRRAYVFIEDCAISSKAPYYFQTQCEAQLPGDKIAAI
                     FEQAILREREQQDTALEGGQRVYDLTDTIVLLGEMEPVSLQEVEQLASRYGKHVVYISK
                     NQRHIPALNFSSCYLRWWQQEGGLFMTREETIAIEDSRIPLICIYYDKDIDIIYFLHEL
                     RGQFARDGYQSWIAVDQSAAVLHDMEYTLPSNASNGLQELLYNAGTMAYNAYTDIAILC
                     VEATNITHCTKERVLLDVDIELSILVKAETERIYISIRTEQGYLKEGVLSNLNVGDIGG
                     IYTYLEQLLVD"
     misc_feature    complement(15710..15730)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 24.71"
                     /tool="antismash"
     gene            15828..17342
                     /locus_tag="PPYC2_RS01735"
                     /old_locus_tag="PPYC2_24970"
     CDS             15828..17342
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019685877.1"
                     /locus_tag="PPYC2_RS01735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_24970"
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="WP_023986630.1"
                     /transl_table=11
                     /translation="MAAAVKAKMIVDKSFRIAEVDKRIYGSFVEHLGRAVYGGIYEPTH
                     STSDESGFRNDVKELVKQLDVPIIRYPGGNFVSGYNWEDGVGPVASRPRQLELAWRTVE
                     PNEVGTNEFFKWAKDVGSEVMMAVNLGTRGIDAARNLVEYCNHTGGSYWSDLRRSHGVE
                     QPHKIKTWCLGNEMDGPWQIGHKTAEEYGRLAVESAKAMKLIDPDIELVSCGSSSSTMP
                     TFPEWEATTLDHTYEVADYISLHQYYGNHDNDTANYLARSMDMDHFIHTVISTCDYIKA
                     KKRSKKKMMLSFDEWNVWYHSNDADKKIDPWSVAPPQLEDIYNFEDALLVGSMLITFLR
                     HADRVKMACLAQLVNVIAPIMTENNGKAWKQTIFYPYLHASRYGRGISLMPVVDSEKYD
                     SKDFTDIPYLDSAVVYDEEGDALTVFAVNRHLSESLELTVDVRSFEGYRIVEHTVLEHD
                     DLKATNSPAGEKVTPHNGGNAKLEDGIVKAHLGKASWNVIRLAKSH"
     misc_feature    complement(17399..17415)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.36"
                     /tool="antismash"
     gene            17763..19658
                     /locus_tag="PPYC2_RS01740"
                     /old_locus_tag="PPYC2_24965"
     CDS             17763..19658
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0051082 - unfolded protein binding
                     [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820229.1"
                     /locus_tag="PPYC2_RS01740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_24965"
                     /product="HSP90 family protein"
                     /protein_id="WP_071559454.1"
                     /transl_table=11
                     /translation="MSQTDQYRFQVNLGGMIDILANHLYSSPRVFIREVLQNATDAITA
                     RKELRKVVAESKVLKEDKALGDTASESNDYEGKVIVELSGSGEHQVLMIQDNGIGLSEE
                     DIHRFLSIIGQSSKKGADLLASETSFIGRFGIGLLSCFMVSDEIVVLTRSVKEGISMEW
                     RGKPDGTYTIRRLETELPVGTQIYLRCKPGSEFYYEPAHVEESLIYYGALLPYPVMLSV
                     DGETKRVNLPSTSWMQDPEQLRSRRSEVLDLGYRLMGERFSDFIPLRTASGRTGGIAFI
                     LPRSVNLNSKRLHRVYLKHMLVSDKAENVLPEWAFFIKSLIWTDELQPTASREYFYENE
                     QLDDVRSELGTCIREELLRMAQYEPDRLQHWIRLHELSMKALAVEDDEFLRIMYRWFSF
                     ESTFGRRELKELIREADGRPLHYTSTVDEYRQITHVAAAQSMLVINGGYIYDSDILEKL
                     PWIDSNLQTERLSPEEVSLSFTGLTQEERENYYGVLRVMDGALQPMRCRAELKRFEPAS
                     LPVLYTISQDALTLRSMENTVEETTSLFSNVLDSLKAGVQQNSGYSTLYFNLNNPVVAR
                     ILEATDTQMVTAATEMMYVNALMMGHYPMNRSELGLMNRSVLHFINWGLGNGQNS"
     gene            19683..20744
                     /locus_tag="PPYC2_RS01745"
                     /old_locus_tag="PPYC2_24960"
     CDS             19683..20744
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820230.1"
                     /locus_tag="PPYC2_RS01745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC2_24960"
                     /product="hypothetical protein"
                     /protein_id="WP_071559453.1"
                     /transl_table=11
                     /translation="MEDTIYDLMEQAQDLPGGAAKLAILEEAVRLADTSGLKELAYEIR
                     GEIVDCAIFNGYPLKSLIAFSWQLGQFDQNPEEYDPVELLWNYKWILGKVCSFSNISKT
                     QIEDLAEDMRRRYAEYGYNERPYYYYKFRIAMDMGELDEARRYLDTFRLIESDSMSDCE
                     ACEQSQMVRFYYLTGEDEQALAVAKPILSGRMKCAEVPHVTLSQVLLPLYRQGEVDQAK
                     DNHRKGYRLIRDDRDFLKTIAEHIEYLAVADPIQGIEVVERHLHMALDYESGLEQMYFY
                     ATMVSLLQKLDTSGEKRLIRLPASLEWGKEDRTLTEIIAYFRPLAESAAADFDRRNGNT
                     FYSDWIGKIVQTA"
ORIGIN
        1 tcacgagctg ggagttgaac accccgtaca tataggaggt ggttgtaatg gtttcttcct
       61 tgcctcctgc gtaatgcccg cccattaaaa tgtgcccatg gggacgctct acacgaagct
      121 ctttggattt gagtacgaca tgctcatagc tgtccgtgaa aaaggaaagt agttcatctc
      181 catcccgttc ttcttcctgc cgtttcggga aaagttgatt cacttcggca gcggttaagt
      241 ccagcgtgcg cagcggctca ccgatggttt gagctggagc cacacgccct gcctgaagat
      301 cacttgccgc gtgtgccggt atactggtct cggaagcgtc cgctagaacg gtagctactt
      361 cgtcacgtgc ctttgtcacc agctcctgat actccagctt tgtcactgcg gctggatgat
      421 tgggctggaa cagaccgtaa aaagtaaagc gagcttcccc ggcaagtttc acctgctcag
      481 attgcaacgc ggtataggcg aattcgtatt ggtacacttc attggcgagc gagtcacgat
      541 ggagtgcttc cggctcattc gtttctttgt acgaaagtcc aaagaactga aatccgtcag
      601 tcgagtaacc aacagtgcgg gttaacgagc cttgttgaat gtatgggaac gcctgacttt
      661 gaggctggtt ttgacgtgag caaacggtgt agcctctttg ttcatcatgg tagacggtgt
      721 ggtcaatata ttgagacaaa taagcttcat tactgcgcac agcggcggta tcggcaatgc
      781 caatatcctg accgtacacg acatctgctt ccacgtcatc gccctgtagg gttacatccc
      841 agaaccatac tcccaggcgg cttagcgtga aggtcacctg atagcctaca ccagcggtga
      901 aaccttccca aataatctgc tgatccgttt gtcggatgac tcccggtgag cgaactccaa
      961 gcaggggagt gatacttaca ccggacggac ggtacaatct caagtacaga ttgttcaagg
     1021 aaccgtcgac tgaattggtc aacagttggt tgatcatcgt tgagccgtga gcgatcttat
     1081 acacatcacc gctgctcaag aaggtaaaag acaggtcgcc ggctcgtagc aaaatatttt
     1141 gatccagact tgtattcatc aaagggaacg cctcactttc ctgtttattt cactaaccga
     1201 aaacggcttt cactagtatc tcggctgtta ggtcctgtaa agacggcaaa ttcaccgctg
     1261 tcactactga agctcaaatc tgcatgatga tagcgcagct gaggctcggt caatgcaaat
     1321 tccacttccc ggctttcgcc tggggcaaga aggactttgc agaaatcttt cagttctttc
     1381 attggacgaa ccgtatcacc gctgatatca cgaacataga actggacggt ttcctcgacc
     1441 ggacgtgttc ctgtgttcgt tacctgcact ttaacggtca gttcctgacc gggtataagg
     1501 gtatcgccgg aaagctgtac gctgtcatag gctacatcgg tgtagctcag tccatagccg
     1561 aacgggaata aaggttcgtt tggtacgtct agatattggg acacgtagcg ttcttttgta
     1621 ttcggatcta actgcgggcg tcccgtatta aaatgattgt agtacacggg cacctgtccg
     1681 accgattgcg ggaatgacat ggtcaggcga cccgtaggtt cggcatcacc gtacaacaaa
     1741 tcggcaatcg ccgcgccgcc ttcaccacca gggaaccagg cttccaatac ggcgtctgct
     1801 tcttcaatga caccgtgcag atccaacgga cgaccattaa ataatacggc taccataggc
     1861 ttgttcagcg tcttcaggcg cttcactagt tccaactggg cttgtggcag gcgaatattg
     1921 gaacggctgc ctgcttcacc actcatatcg gagcgctcac caagcgccaa cacgataacc
     1981 tctgcttggc tggctgcttg cagagcttcc gcatattgct cctcagttat atcgtcgata
     2041 gagcaacctg ccgcaaccgt gagcagcgag gaggatattt tcgattggaa tccgtcaaca
     2101 acgcgaatag cttcctcctg tgaaccactc cacgaccaag agcccaggat atcaccgctc
     2161 tctgcaaaag gtccgatcaa cgcaatatgt tgattgcgat tcaatggaag aacggaatca
     2221 tttttgagca acacgcaaga tttaatagct aattctttgg caaccgtacg gtgagcttcg
     2281 cagaacacaa cttcacgttc acgctcaggg tctgcgccgc gtagcggatt ttcgaacaag
     2341 cccagctttt gcttgagctt caatatacgc atcacggctt catcaatgag cgcttcatcc
     2401 agttgtccgc tgcgaaccag ctcaggcaga tgcccgttat agcaggaggt catcatttca
     2461 atatctacgc cagccagcag tgctttcttc gctgcctcgc gctcatcctc ggcgatgccg
     2521 tgagggataa gctccttgat ggcggcccaa tccgagatga gtacaccatc aaagccccat
     2581 tcatcacgaa gcaaatcacg catcaggcgc ttattgcccg ttgcggctac accttctacg
     2641 gtattgaagg acgtcattac catttcgcag ccttcatcta aagcagcttt gtaggagggg
     2701 agataatact ctcgcagctg ccatgcggat acatctacag tgttgtaatc ccgtccgcct
     2761 tcgccagctc catatgcggc aaaatgcttc acgcatgcgg ccacccggtc ggtatcgttc
     2821 gtcagatctt taccctgaaa cccgcgcaca aacgcacgag caaattcgct gttgaggtaa
     2881 gggtcttccc ctgtagattc catcacacgg ccccagcgcg ggtcacgcac cagatcgacc
     2941 ataggagcga atgtgacgtg aacaccggat acagctgcct cgcgggctgc aatggtagcg
     3001 ctctcttctg caagttgcat atcccatgag caaccaatgg ccagcggtat agggaaaatc
     3061 gttttgaagc cgtgtacaat atctgccata attaaaagcg gaatacccag acgattttta
     3121 ctcaaatgag cctgctgaac acgaatcgct tccttggccc ctgcgatacc aagcacggaa
     3181 ccgacgttat ggacattttt ctctgtgatg ccgagagaag ccatagggcc ggtaatttga
     3241 ctatccgttc ccgcttcttc aaagaaggca cccacaagct gtagcagttg atcgactttt
     3301 tcttcaagcg tcatgttttc taaataggaa ttcaggtgtt gttccatcat aatcctccat
     3361 aagctgtatt gttggtggac agctcttttt tttcagattc atgagatttt ttggataaaa
     3421 ttgattcaaa aaagtgctga acaggctaat agctagtata gaagcataat attctgtcgt
     3481 attattaatc gaaacgtttc tattgttgaa ctcagttgga ttatatacgc tttcaaatag
     3541 agagtcaaat ccaattcagg gggtttttat aggctaaata acgtaataaa gatgatataa
     3601 acgaaaaaaa gtcgggattc tgagcgaata aaatataata ttcctattga atacggtttc
     3661 aatttgttct ataatgacta tcgaaacgtt tctattgacg ggtatggtcc ttgtgctttg
     3721 aacataagtg ttatagcggt atgctttaat cgctatgtat ttacatgcat caggattttg
     3781 caagattcga ttccagtcgc tccaaaatgc aatatataga tgaacgagac catttcgttc
     3841 tatatattgt tcattggaag tcgctaattg tattttcgca aaatcctcgt atttgaatcc
     3901 gttatcatat tgcatgatcg gtaaaccgat catctcggga ggaattcgta tgatgaaaag
     3961 aacgttgggg atcattttgg caagcacctt attactgggg ggcgcgctgg taggttgttc
     4021 gtccaaggat gattcgtccg gtaaagatgc gaacggcaag acgaccatca ccatgtgggg
     4081 catgggagca gaagggaaac tgctgcctga aattgtaaaa gattttgaga aagaaaatcc
     4141 agatattcac gttgatgtac aggcgttgcc ttgggataac gctcacgata agctgctgac
     4201 agcagttgct tcaaaatccg gtccggacgt ggttcagtta ggtacatcat gggttcccga
     4261 acttgcgtct gcgggtgcat tgacggatat taccccttat atcagcaagt atcctgaact
     4321 ggaatcgaag aatttcttcg agggtgctgt aggtacgaca aaatttgaag ggaaaccggt
     4381 cggtgtgcct tggtacactg aaacgagagt tttgttctat cgttccgacc tactgaaaca
     4441 agtcggatat aatgaagcac ctaaaacgtg ggaagagctt tccgatgctg cccaaaagct
     4501 ggcggctcgg ggcaaaggca aatatggtat ctcctttagt gcaaaggagc agtctatggg
     4561 ctttatgttt gctctccaga acggttccaa actggttgac gagcagggca atccgctgtt
     4621 caaccaacca ccgtttgtag atgctgtgaa gtatttgaat acctttttcc aaaacggctc
     4681 taacgcagtg gatattggaa ttgactctgt tcaaggttta caaggtgatg gtatcgttcc
     4741 aatgtttatc agcggtcctt ttatgattaa agaaatcaag agcaaggcac cagaactgga
     4801 aggtaaatgg aatatagcgg agcttcctgg caaagtaaac aacctgtccg ttttgggtgg
     4861 agcgaacctt tcaattatgc aattcagcaa gcacccagag gagtcggcca aattcatggc
     4921 ttacatgagt aaaccagaaa cgcagctgaa atggatggaa ctgtccagta acttgcctgc
     4981 ggctactaaa tcgtgggaag atgccaagct taagagtgat ccgatgcttc aaacgattcg
     5041 taaacaactg gaccattccg cagcattgcc gcaactggca gcatgggaag aggtttctca
     5101 acaattcatc aagagctttg agcgtgttta ccgtggtcaa gcggacgtac agaaggaaat
     5161 ggatgacttt aatcagcagg ctgcaagtat tatgaaaaaa taatgatcca tatccgccat
     5221 tgtcaaaggg agtgaaggca tgaaaggaag ctcgcagaag cttgcgccat acttgtttat
     5281 cggtccctcc atcatcctgt taacgctgtt ttcgctgttg ccgattctac tggcgctcgt
     5341 aatcagcttc acggatatgg atctgtcagg actcgttaat tatgatagta ttcgctttat
     5401 aggtctggaa aattatacaa acgtactaat ggacccttcc tttataaagt cccttggtaa
     5461 taccctgttc ttcgtcatca tcggtgttcc gttggtgctg atattttcgc ttagcatcgc
     5521 gattctgatt aacatgggga aatcacgtgc tttcaaagta ttccgcgtcg tgttctatct
     5581 gccgtccgta acgaatgtgg ttgcggtcgc agtggtttgg agttatctgt ataatccgac
     5641 gcttggatta ttcaactacg tacttggtct gatgaattta ggtcccgtcc catggctgac
     5701 cgatccaaca gtagcgaagg tttcgttgat tgtgttggca gtttggcggg gcatcggctt
     5761 aaacatgatt atttttattg cggctattaa agggattccg ggttcttatt atgaagcggc
     5821 tcagcttgac ggtgccaata catggcagca aattcgttat attacgcttc cgcagcttcg
     5881 ttacgctatt ttcttcgtgt ccatcacgac gatgattggc tggctgcaat ttttcgagga
     5941 accgtttgtc atgactaaag ggaaaccgct cgatggcacg ctgacagcat ccctgttcat
     6001 ttacaataac ggcttccaat ttagtaaatt cgggtatgcc gcggcgggat cgttcattct
     6061 gttcttcgcg atcatcgcgg tgacgctgat tcagttccgt ttgcaaaata aagcggagtc
     6121 ctgatagaga gaggtgatga acgtgaaaac agctgttcag caagcccgcg ccaatacgcg
     6181 cagtggtgaa aaaacatttc aatggttcgt ggcgattctc ctgaccgtgg gaggtctgtt
     6241 gatggtgctg ccttttgcgt ggatgatttt atcctccttt aagacagaga gtgaggtaac
     6301 caaaattcct ccgaccatct ggccgcagca ttttacactg gataatttta aattactatt
     6361 cgatagcatg gcttttggaa cctatctgac gaatacgctg atcattgttt tagcttcctt
     6421 cttcggatta ttcctgaatg ccatggcagg ttatggcttt gccaaattcc aatttaaagg
     6481 caaagggttt ctattctacc tggtactggc aacgatgatg attccaggtc aagtgacgat
     6541 gattcccgtc tacttgatcc tgaaccagat gggattgacc aattccatgc tagggattgt
     6601 ccttcctgga ttggtaggtg cgttcgcgat cttcctgttc cggcagttca tgtccgatat
     6661 cccggaagaa ctgctggagg cgacacgtct cgatggggca ggggagttcc gtacttttct
     6721 gcaaatcgta ttgcctatct cgacaccaat tctggcagta caggccattt taacctttat
     6781 tggtggatgg aatagcttcc tgtggccgct cattattgcg aacgatgaga agctgtacac
     6841 cttgtccgtc gggctgtcac tgctcaaggg gcagaacgaa agtcaatttg ctcttcaaat
     6901 ggcaggctcg accttcatgg tcgttccgat catgattatc ttcattgttt tccaaaagta
     6961 tattattgag aactacacga tttcggggat taagtaatag tgtagtatga atacaagtca
     7021 tagtcacaag aacgaacagc ggagcttctc tttgggagag gggctccgct gtttttactt
     7081 tacatagata tatttatata tgagttagac aatattgatg ggataatgta cgaagttttc
     7141 ttttcagtct gtagattcga gtcgttgtag ccgtaaccga aatattatat ttggtagcga
     7201 gcaggggcac agccagttgt cgacaaaagt agtcttcata gagtgtatat tcaatgttgg
     7261 aaagctgcat tagaatatta acgataaccg tatccacatc tcccaatcta cgattttccc
     7321 actcctcctc taccgaattt gaaaaactac agatcttctc acattcaagc gtagtttcat
     7381 gctttttttg tgtatagtag cacctaaatg atttatatat aagattttta gccgtaaggt
     7441 atagccaacc ctttacattg gggtgatgtt tgagcttgac caattgctgt cttgccgcta
     7501 caaaagtatc ttgtgtacat tcttctgcca taaatgtaaa gcaagactga ttcttgatta
     7561 aatgcataca gaaacgatat acctcactca gataaagttc acaaattttt ctgtaaaagc
     7621 atctggaact acctctgcac tgatcctctt tgcaacagtc gataaccatc gtagtcggca
     7681 ttgttcaagc cccctttgga cggataaaaa aataaatgat ttttgtatgt gccaatcata
     7741 tacattaatt ccaattttca agaatgacat aaatcatatt taatctcgta aatgtggaat
     7801 tactagaaca gttaaaagat attttaaagt gattttgatt ctgatacgga attagttaat
     7861 agggggagag ggtgcacctg gtgaaagggg ggaaggatga aagaatccat agtatataaa
     7921 cgtttggcag caacatttag accttatctg aagacggtca ctatcatttt gatatgtctc
     7981 atcctatcag cgggcttgaa tatattattg cctttaacaa gcaagattat tgtggatcaa
     8041 ggtctcctgg aagggaatat gcaggctgta atcctgtaca cttctgctgc gtttttaatc
     8101 gtttgcttgg ataagctgct gaatgtgtgt aaagaaacct ttcgggcagg cttaagcgca
     8161 caggttacct tttcattatt tgaaaaggcg tatctgcatc tgacaagagt acgaatgagc
     8221 tattttaacc gaaccaatga agcggagcta ctgaaccaaa ttggcacgga tgtaggcaat
     8281 gtatcgagga tcacagatag tggagtattt tttgtcatta tgcaggcgtt cagcatgatt
     8341 ggtggtttat gtggtttgct gctcattaac tggaaaatga ctgtaatcgt gctgtgcttt
     8401 ttacccatca aatatgttgt ggtgaagtat tttgcgaagc gtagaaaaaa actggtgggg
     8461 gatttaattg aaggcagtag tgattttgcc cagtggtttg gggaatctgt cgggggcatg
     8521 aaggaacagc gaatgtttgg tcttattcca cataagcatc agcagttctc atccaagcag
     8581 cgtcgaattg tagaatcaga acggaaatta tcacttctgg acgcctggaa tatcgcttcg
     8641 gaatctattt taattcagct tctaatgatg tttttgtacg ttgtgggtgc taatcttatt
     8701 tttcgtttac agcttactgt aggtgggatt tttgcctttg tttcttacag tgcttatgtt
     8761 accactcctg ttttcgctat tttaaacatt ggctacatgc tggctgaagt cgttccctcc
     8821 gccattcgat attatcagtt cttggattgg gcagaggaag aaacatctaa ttcagtcact
     8881 ccagcgtctt tactaactga gccgccattc gaagatcaca ttgcatttca taatgtttct
     8941 ttttcctata ccaaggacga acccgtactg ccccacgtga gctttaggat tgcccgaggg
     9001 gaaaaagtag ctatcattgg agcaaatggg gcagggaagt ctacgttgct ggatctgatt
     9061 atgagattca gccagcctga tcaagggata atcacttatg acggcattga catccaaagc
     9121 tatgagatag atgagtatcg aagtcaaata gctttggtca gtcagcaggt gtatttattt
     9181 gatactacta tttttggcaa tatccgcata ggcacagaag tcactaatga tgcaatagag
     9241 gccattatcg cggaggttgg tctggaagaa ttggttcaga actcggcaga tgacttccct
     9301 ataggctcga atggctccag attgtcgggt gggcaaagac agaaaattgc tatggcccgg
     9361 gcattgatca gggaagcgcc attgtttatt ctcgacgagg tgacctccaa tctagacaca
     9421 gcagctaggc taaatgttca gcaattgttg aagacccggt tgcgtgaaaa gaccgtaatc
     9481 atcgttacac atcgcagcga gatattagcg catgttgata gagttatttt gttggagaac
     9541 ggcgaaccag cccaaatagg atcacactcc cattttatga cctgtcatgc agaatacaga
     9601 ggatgggtat taggggaaga agaggtcccc ataaaatgat gaaaaaaaca aacgctttca
     9661 tagtgtgatt taacaccatg tacggaatta gtataggtga acaccttttt aaatcatatc
     9721 atgaatggga ggagtagttt aacatgcgta agcttgtgaa aagaagcacg aatgtaggcg
     9781 acacgattga ggcatttggc tgtggttgtt cctgttattg tccttgctcc tgttattgcg
     9841 caggcagttt gactcgaagc tccaatactc agcgtgaaag tgacggttct tatcgcagag
     9901 ataacggaac tggaattggt aattattaag cttgtatctg tatggaggag cctgggcatt
     9961 ccaggcttct gtccacatca aaacagagta ggtgtgaatc atgaacatgt gccaaccctt
    10021 tatatacaca tttcagacga gactccacca ttatgtatat gatgtaaata ccaatttaat
    10081 tttgaggatt aaagaggagg cttaccattt cctgaattcg cattccagct tcgacctgga
    10141 tcagatggag gctacaccgg aattgcagca ctatatccgt gacttgttgg ataacggatt
    10201 tttatcttca cagcgtccgc agattatgaa tcatcccaag acaaagcacc tggagcatat
    10261 gcttcagcat cagctgaaga ccctcacctt acaggtaact caaaattgca atcttagatg
    10321 ctcttactgc gtttattcag gaggatatga caatcgaggt cataccagtc tgatgatgga
    10381 ttttgagaca gcgcgcaagt gtattgattt tgtcattgat aggtcagtag acagtgaccg
    10441 tttggatttt ggtttttatg ggggagagcc gcttattaat tttccgttgg tcaagaagtg
    10501 tgtggaatat atcaaggagc aggtagcgta tagagatgta ggctttcatt tgacgaccaa
    10561 tggtacgctg cttaatgacg atattttggc ctttctggat gaacatcgtt ttgtgcttac
    10621 gatcagtctg gacggagatc aagagaatca tgacagaaac agacgatttg ctgttaacgg
    10681 gcggggcacc ttcgatacga ttattgccaa tgtggataaa attaagagaa attacccgga
    10741 cctctttgaa tggattaatt ttaatgtggt gctggatacc cgtaatgatt ttggttgtat
    10801 caatgatttt tatacgaatt atgaaacctt cgaaagcctg tacagtgtaa ggtcgtccta
    10861 cattaacgat gcttatgtga aggatgaaat tttgtacaga aatgaattta ttgagcagag
    10921 aggctatgag gtagttaaaa tgatgctttc caagtttgga agagtagatg aaaatcatgt
    10981 ctccaagctg attaaggact attatattca gatgtatttc cgtatgtttc attatagaaa
    11041 gccttctgcg ggaatgccga tagaagcgca tcatggtgga ccctgtgtgc ctggtgtaca
    11101 gcgattgttt gcggatgtgc atggaaatct ctatccatgt gaacgggtca gtgagcagtc
    11161 ggaggtggtg cagattggaa aggtggacac aggctttgaa gtggataaaa tcagccagat
    11221 tttgaatgta gggacaatca cggaggatgc atgtaaaaac tgttggaatt tccgtttttg
    11281 tacgctgtgt gttgctgtag cagatgattt gcataccttg tccaaagaaa agaagctaag
    11341 tcattgttcg gtagtcaaaa atgatattag gcacacctta cttgattatt gcatgatgaa
    11401 tgagctgggc tatgatttct ccgaggatac gattctcgat tttgaaaaag catgaggggt
    11461 gtctccatga ccaataaatt aatcattttt ccgtttgatt atgaaacgat agccctggtt
    11521 aggaacttga atctattagg aagttatgag gaagttgtac ttatttcttt tcaagggtcg
    11581 ggtatgatcg ggaaagatgc ctgtgtaacg gacaaggggg aagtgacagg cttcatagtg
    11641 aagccagagt cttgtttgga gcaagaaatg gagcgttgtg atgccatatt actggtgaaa
    11701 tccaatttca agctggatgt agctgaggtg tatcttcccg tgatccagaa ggctggacaa
    11761 cttggcaaaa aagtcatgtg taatttcact ttgccagact catgtatgga attcatcgaa
    11821 ccctgtgagg agcaagatga caagctgatt ttaaaaaata catttgatgt acgcacgaaa
    11881 gatattttac cgcctgaccc gggctctgtt attcatgatt tttttacacc ggttctgttt
    11941 gtattagggc tgaacgagcg aacgcataag cttaatttgc agcttaacct tcggcagaag
    12001 cttgaagcac aaggatatcg ggtgtcgcaa atcacatcta atggatgcgg ggagctgatt
    12061 ggtgcacatt cttttccaca gtttatgttt gagagcggta tgacggaaac ccagaagatt
    12121 atcatgttta atcggtattt gaaaaaaata gagcagagcg aaaagcctga tctaatactc
    12181 gtgggcattc caggtgggat tgttcccttt aacaatacgt tcacgaatta ttttggagta
    12241 acctcatttt tggtatcccg cgctgttaga gcggatggcc taatctgttg tcttcactat
    12301 gatgaataca atataaaata tttggagcat gtgaaacagt acatggaaaa ccgtttttcc
    12361 tcttcattat taggatatgc catatgtaac aatgtattcg acagttactc ttcttccaca
    12421 gtcaatatgc aatatgcatc tgttgatcat cgtttcgtgg aagagaaaaa gcaggagttt
    12481 tccaattatt ccgtgcctgt actccatctg tccaacgatg aagatatgaa taggctgacg
    12541 caggatattt tacattattt ttcggttgat catcacgtag ttcagttgta atggagggaa
    12601 gaacatgaac tttactcagg atgtaacggg aacaggaatg aaactggaaa atatattttg
    12661 gaagcttttt aaaataaaag cgggtgagat aaataaagag gctacattac tgggtcctga
    12721 tatggggttg ttccccagag atctggtata tctattattt gaagtggaaa aaagctttgc
    12781 tatcctaatt ccggaagagc gtatagtggg aggggggttg cttacatata acagcttgta
    12841 tgagacgata aaggactgct taacagtgga aaaggaatga aggatttgtg aaaatgatga
    12901 taaaacatac aaaaacatac aaaaaaatcc gatatacctc tagaatcact tatttcagga
    12961 tttttgaaaa atcctcattt agaagagaat tggaggtttt aggatgaatg tatcatttac
    13021 atcatctcac caatcgccgt tccgcaccgc agataacaac cgacttgaac tacggcattc
    13081 cctttccgct caggctgaaa ggaagggtat aggcaagcca caaaacaagg ttattcaaca
    13141 attgacagag caaaagcaaa gtttgatgga gaggcgttcg gactatttaa gtaatgctct
    13201 caagcgtggt ctcggtccgg aagctgtaaa agctgaaatg gaagagatag ataagcagat
    13261 tcagcaaatt gacgagaaca ttcaaaagca gtcactggaa gagcaaaaaa aggctttagg
    13321 catggatgag gaaagtaaaa aagaagctca gaaaggcaaa aaggaagaat atacgcctaa
    13381 gactgctgag gagcagcagc aaagattgat cacctataca atgcatagta ttgtatctgc
    13441 aaacaatgag ttgaagagtg ccaaaatagc caaaacggca caaattacat tgggaagcga
    13501 ggctaagggg tgggaaaacg ctaaccctgc aaaatcagcg gctttgcgtg aaaaggcaga
    13561 aggacttaat ggagaaatca tggaaatcgc tgcgaatatt aatgagcgta tcagcgaagc
    13621 agtgaataac gaaccgatga ttacagatcg ggttgaacct aaggatgagc aggaggcgaa
    13681 tgcagaggct ggcagggtgt ggactgaaca agagctcaat gcctatctag actcggctaa
    13741 agacggggcg aagactgcag gcacgaaggt aaatattgca gtctgatccg gctatcatgt
    13801 acatggttcg ctaaattagg agggtgcttt cagacgaacg ctatcgttcg cagaggcacc
    13861 ctccgcttac tctaatggaa cggaacagag ccgtgagatt catttcacaa tccgaagaga
    13921 cagggggaga aaaaatgaat ggcaagatcc atgtagccat tattgacgac ggggttaatg
    13981 ctggcttttt aaacacccaa ttattatata acgtcgaaat agctcatgga gacgtagaag
    14041 atggacgcac cttaaatcac ggtacgatat gtgcagctat tgtacaaacg tattttccag
    14101 atgcgatcat cagtagtgta aaaataatga accatagaaa aggaaatgca gctcagcttt
    14161 gtgctgcgct ggattggtgt gtaaagcatg gtgtacaggt agccaatatc agcctgggaa
    14221 gtataaatta tcgagatcga ggcatgctac gggaagctgt aaataatgca gctatggcgg
    14281 gattaattat ggtatgtgca gcacaaaatg gaggacttct tacttatccg gcttcctttg
    14341 ccaatgtgat tggtgtgcgc tgcgatcata gcggtatact cacagcagga caatatacat
    14401 atgatgctga gaaagcattc tcaagtggta tcgattttac cgcttttgcc aagcatgaac
    14461 tggtaggtgc agctggagag gctgtacaat gtcccaacag caacagctat gccactccat
    14521 tgattacagc acacatatgt aaagttttgc agcagtccat gcctgttcct tccatagaac
    14581 agctaaaaca tattttacat aagtatagtt atcttccgat acaggatacc ataatccccg
    14641 taatgcgtta cggacatccg gattggatac ggcgcgccta tgtgtttata gaggattgtg
    14701 caattagttc gaaagcaccc tattattttc agacccaatg tgaagctcaa ctccctggcg
    14761 acaaaattgc tgcgatcttc gaacaagcca tcctgcggga gcgagaacaa caggacacag
    14821 cactcgaagg tggacaacgg gtatacgacc ttacagatac gattgtcttg ctaggggaaa
    14881 tggagccagt gagtttgcag gaagtggagc aattggcttc acgttatgga aaacatgtcg
    14941 tctatatctc taaaaatcaa cgacatatcc ccgcactgaa tttttcatct tgctatttgc
    15001 gctggtggca gcaagagggg gggctcttta tgacgcggga ggagactatc gcaatagagg
    15061 attctcgcat tccgcttatt tgtatttatt atgacaagga cattgacatt atttattttt
    15121 tgcatgagtt gagagggcaa tttgcccggg atggatatca aagctggatc gcggtggacc
    15181 agtccgcggc agtgttgcat gatatggagt atacgctccc ttcgaatgca agcaatggat
    15241 tacaggaact gttatataat gcgggtacaa tggcatataa cgcttatacg gatattgcta
    15301 ttttgtgtgt agaggctacg aatattacgc attgcaccaa agaacgagtt ttattagacg
    15361 ttgatattga gctttctatc ctggtgaaag cggaaactga acgtatttat atatctatac
    15421 ggacagagca gggatatttg aaagaagggg tcctctcgaa tttaaacgtg ggtgatatag
    15481 gtggtattta tacatattta gaacaactgt tggtagactg atattcacta tttaaaacag
    15541 actgcaagat atggcagtag gcactacttt gaacgcatca gtaatccgtt attactattt
    15601 agcaaagtgg ttattcactc aataagtttg tttataaaac gaaatatttt gaagtacgta
    15661 accaattgct tatcgtttat cattaatgtt aataaatata ttaagtattt aataataata
    15721 ttgactataa taaatatggt gtgttatatt aaaaccgtaa ataaaacggc ttcttagtct
    15781 tggtggtaca acggatttta ttttcgcatt cagagaggat ggtttaggtg gcagcagctg
    15841 taaaagcaaa gatgattgta gacaaatctt ttcgtattgc tgaagtcgat aaacgcattt
    15901 atggctcttt tgtagagcat ctcgggcgtg ccgtatatgg cggcatttac gagcctactc
    15961 attcaactag tgatgaaagc ggtttccgaa atgatgttaa agagttggta aaacagcttg
    16021 atgttcctat tatacgctat ccgggaggca actttgtatc cggttacaat tgggaggacg
    16081 gtgtcggccc tgtcgcgtcc agacctagac agttggagct ggcttggaga acggtcgagc
    16141 cgaatgaagt gggtacgaat gaatttttca agtgggccaa ggatgtaggt tccgaagtca
    16201 tgatggcggt taatctgggt acgcgcggaa ttgatgctgc gcgtaatctg gtggaatatt
    16261 gcaaccacac aggtggctcc tattggagtg atctacgtcg tagtcacggt gtagagcaac
    16321 cacataagat taaaacctgg tgtcttggta acgagatgga tggcccatgg caaattggcc
    16381 acaagacagc agaagaatat ggtcgtctgg ctgtagaatc tgcaaaagcc atgaagctga
    16441 tcgatcctga cattgagctt gtatcctgtg gcagctccag ttctacgatg ccaacgttcc
    16501 cggaatggga agcaaccacg ctggatcata cctatgaggt agccgactat atttccttgc
    16561 accaatacta cggaaatcat gacaatgata cggctaatta tctggcacgc tctatggata
    16621 tggatcattt tattcatacg gtcatttcga cttgtgacta tatcaaagca aagaaacgca
    16681 gcaagaaaaa aatgatgctc agctttgacg aatggaacgt gtggtatcac tccaatgatg
    16741 cggacaaaaa aattgatccg tggtctgtgg caccaccgca gcttgaggat atctataact
    16801 ttgaggatgc attgttggta ggcagcatgt tgattacgtt cctgcgccac gcggatcgtg
    16861 taaaaatggc ttgcctcgcc caactggtca acgttattgc gccaatcatg accgagaata
    16921 acggaaaagc atggaagcaa acgattttct atccgtattt gcatgcctcc cgttatggtc
    16981 gtgggatatc gttgatgcct gtggtggact cggaaaaata cgattccaag gacttcacag
    17041 acattcctta tctggatagc gctgtggttt atgatgaaga gggagatgca ctgactgtct
    17101 ttgcagtgaa ccgtcacttg tctgaatcgc tggagctgac agtagatgta cgcagtttcg
    17161 aaggctaccg cattgtcgag catactgtat tggagcacga tgatctcaaa gcgaccaaca
    17221 gtccagccgg tgaaaaggtt acgcctcaca acggcggcaa tgccaagctt gaagacggaa
    17281 ttgtaaaagc tcatttgggc aaagcatcgt ggaacgttat ccgtctcgct aagtctcatt
    17341 aattcctttc tgtaaaaggt acagcttcga ctgtatctaa ataagctcgc attctctctt
    17401 gtaagagtat tacaagagcg gcaatgcgag ctttttgcgt aaaatgagcc atttgtccct
    17461 ccatagatat aggtttttaa gagaaggatg gattttaaat aaatattatg tttattacta
    17521 aatttaacta gacaaagatg acctttattc actaagtgct cgtactccgt acatttttat
    17581 gaagttaatt agacccagtt ccagacttcc taggtgaaaa aagaccctgt tatatcgttg
    17641 tcaacgtatt gatatctgaa atgcagggtg tgtaatccga cttaaatcca cgttatactt
    17701 taaaagacag tctatttaaa accagatgat ggttgtagca tttcgagaaa ggaatgatct
    17761 gtatgagtca gacagaccaa tatcgttttc aagtgaactt gggcggtatg attgatattt
    17821 tggccaatca tttatatagc agtccacgag tgtttatacg tgaggttctg caaaatgcaa
    17881 cagatgcgat cacggctcgc aaggagctgc ggaaggttgt tgctgaaagt aaagtactga
    17941 aagaagacaa ggctcttgga gatacagctt ctgagagtaa cgactatgaa ggtaaagtca
    18001 tcgtggagtt atctggttct ggggagcatc aggtattgat gattcaggat aacggcattg
    18061 gattgtcaga agaagacatt caccgttttt tgtcgattat tggtcagtct tccaagaagg
    18121 gagccgattt gctggcttct gagacttcgt ttatcggacg ctttgggatt gggttactat
    18181 cctgctttat ggtgagcgat gaaattgtag tgttgacccg ctcggtgaag gaaggcatct
    18241 ccatggaatg gagagggaag ccggatggga cgtatacgat tcgtcgattg gaaaccgagc
    18301 tgcctgtagg gacgcaaatt tatttgcgct gcaagccggg aagtgagttt tattatgagc
    18361 cagcgcatgt agaggaatct ttaatctatt atggtgcgtt gctgccgtat ccggtcatgc
    18421 tgtctgtaga cggggagacc aagcgcgtca atcttccatc gacgagctgg atgcaggacc
    18481 cagagcaatt acggagtcgc cgtagtgagg tgctggattt aggctatcgc ctgatggggg
    18541 agcgcttcag tgattttata ccgttgcgga cagcatcggg cagaacaggc gggattgcat
    18601 tcattttgcc tcgcagtgtt aatctgaaca gcaagcggct gcatcgggtg tacctgaagc
    18661 atatgctggt gtcggacaag gcggaaaatg ttttgccaga atgggcattc ttcattaaaa
    18721 gcctgatttg gacagatgaa ttgcaaccaa cggcatcacg tgagtatttt tatgaaaatg
    18781 agcaacttga cgatgttcgt tctgaactgg ggacctgtat tcgggaagaa ctgctacgca
    18841 tggcgcagta tgagccagac cgcttgcagc actggattcg tttgcatgag ctgtccatga
    18901 aggcgctcgc cgtggaggat gatgaatttt tgcggataat gtaccgttgg ttttccttcg
    18961 aaagtacgtt tgggcggcgt gagctgaaag aactgatccg agaggcggac ggacgtccgt
    19021 tgcattacac atcgacagta gatgagtatc gtcagattac gcatgtggcg gcggcgcaat
    19081 ccatgttggt gatcaatggc ggctatattt atgattcaga cattttggaa aagctgcctt
    19141 ggattgactc taacctgcaa acagagcgtc ttagccctga ggaagtatct ctttcattta
    19201 ccgggctaac acaggaagag cgcgagaatt attacggtgt gctacgtgtc atggatggtg
    19261 ctttgcagcc gatgcgttgc cgcgctgagt tgaagcgttt tgagcctgcg agtttgccag
    19321 tgttgtatac catttctcag gatgcattga ccttgcgctc catggaaaac acggttgagg
    19381 agacaacctc acttttttcc aatgtgcttg atagtctgaa agcaggagtc cagcagaatt
    19441 cgggttattc caccttatac tttaatctga acaacccggt ggtggcgcgg attcttgaag
    19501 ctaccgatac gcagatggtc acggctgcta cagaaatgat gtatgtgaat gcgcttatga
    19561 tggggcacta cccgatgaac cgcagtgagt tgggactgat gaatcgaagt gtgctgcatt
    19621 ttatcaattg gggattaggg aacggacaaa attcgtaatt gcgtaattat agggggagcc
    19681 aaatggaaga tacgatatat gatttgatgg agcaggcgca ggatctgccc ggaggggcgg
    19741 caaagctggc gattctggaa gaagcagttc gcttggcaga tacttccgga ttgaaggaac
    19801 tcgcttatga aatccgggga gagattgtag actgcgctat ttttaacgga tatccattga
    19861 agtcgctgat tgctttttcg tggcagttgg gccaatttga tcaaaatcca gaggaatacg
    19921 atccagttga gctgttgtgg aattacaaat ggatactcgg gaaggtgtgc agcttttcca
    19981 atatatcgaa gactcaaata gaagatctgg cggaggatat gcgcagacgt tatgccgaat
    20041 acgggtataa tgagcgtcca tattactatt ataagttccg catcgcgatg gacatgggtg
    20101 aactggatga agcacggcgg tatctggata ccttccgctt gattgagtcg gacagtatga
    20161 gtgattgtga ggcctgtgag cagagccaga tggtacggtt ctattacttg actggagaag
    20221 acgagcaggc gcttgccgtg gcaaaaccga ttttgtcggg tcgcatgaaa tgtgcagaag
    20281 taccacatgt gacgctctcg caggtgctat tgccgcttta tcgtcaaggc gaggttgatc
    20341 aggcaaagga caatcatcgc aaaggctatc gcctaattcg ggatgaccgc gatttcctaa
    20401 aaacgatagc ggagcatatc gaatatctgg cggttgctga tccgattcaa ggaatcgaag
    20461 tggtagagcg tcatctacat atggcgctgg actatgagag cgggctggag cagatgtatt
    20521 tttacgcgac gatggtgagt ctgctacaaa agttggatac ttcgggagaa aaacgattga
    20581 tccggttgcc ggcttccttg gaatggggta aagaggatcg cacattgaca gaaatcattg
    20641 cgtattttag gccactggca gagtcagcgg cggctgattt tgatcgacgg aacgggaata
    20701 cgttttattc cgattggatc gggaaaattg ttcaaacggc atagaagaag tgttagctgt
    20761 gacgaatatt ttatacagcc caaacaatga gcaggtataa tgttcctgtg aaatgacagg
    20821 aggggttatg ttgtgactgt aaccgaaaag gtgattaatt tcgcacaccg cggagcttca
    20881 ggtgtatgtc ctgagaatac gatggcggca ttccgccacg ccttggaact gggagcaaca
    20941 ggtatagaaa cggatgtgca gcgtacccaa gatgggcatc tggtgctgat tcacgatgag
    21001 tcgctggagc gtacgacagg ttgctcactg gatgtaaggg atattacgct ggaagaatta
    21061 aataaactgg atgcgggcgg ttggtttgat gagaaattcc gaggtgagcg ggtcccgatg
    21121 ttggatgagc tactggaact agcccagtcc tcgaatacaa ttattaattt ggagttgaaa
    21181 aacagcattt atctctatcc gggtatagag gaagaggtca ttgctgccgt gaagcgtttt
    21241 gggttggaac agcgtgtaat catatccagc ttcaatcacg aatcgctggc gctctgtgcg
    21301 cagcttgctc ctgaaatcaa gacgggggcg ctgtatatcg aaattatggt tcgtccatcc
    21361 gagtatgcaa cccaattcgg ggtaacagca ctccatgcct acaaacaagt tgttacgcca
    21421 gaagctgtat cagaggcttt ggcattaggc gtcgt
//
