LOCUS       NZ_CP017967            24117 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Paenibacillus polymyxa strain YC0136 chromosome, complete genome.
ACCESSION   NZ_CP017967
VERSION     NZ_CP017967.2
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5621728)
  AUTHORS   Liu,H., Hou,Q., Liu,K., Wang,C., Ding,Y. and Du,B.
  TITLE     Complete Genome Sequence of Paenibacillus polymyxa YC0136, a Plant
            Growth Promoting Rhizobacterium Isolated from Rhizosphere of Tobacco
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5621728)
  AUTHORS   Liu,H., Hou,Q., Liu,K., Wang,C., Ding,Y. and Du,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2018) Department of Microbiology, Shandong
            Agricultural University, No. 61 Daizong Street, Taian, Shandong
            271018, China
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 5621728)
  AUTHORS   Liu,H., Hou,Q., Liu,K., Wang,C., Ding,Y. and Du,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-NOV-2016) Department of Microbiology, Shandong
            Agricultural University, No. 61 Daizong Street, Taian, Shandong
            271018, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3.0
            Genome Coverage                   :: 193.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:57:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,961
            CDSs (total)                      :: 4,833
            Genes (coding)                    :: 4,774
            CDSs (with protein)               :: 4,774
            Genes (RNA)                       :: 128
            rRNAs                             :: 11, 11, 11 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 11, 11 (5S, 16S, 23S)
            tRNAs                             :: 91
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 19 of 59
            Pseudo Genes (incomplete)         :: 37 of 59
            Pseudo Genes (internal stop)      :: 15 of 59
            Pseudo Genes (multiple problems)  :: 12 of 59
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:21:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1428212
            Orig. end                         :: 1452329
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017967.3.
            On Feb 23, 2018 this sequence version replaced NZ_CP017967.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24117
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="6"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..24117
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24117
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14117](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14117
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(10..23)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
     gene            232..1152
                     /locus_tag="PPYC1_RS06065"
                     /old_locus_tag="PPYC1_18235"
     CDS             232..1152
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821230.1"
                     /locus_tag="PPYC1_RS06065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18235"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_071639875.1"
                     /transl_table=11
                     /translation="MQQATGQVPVIRMEGVSKIISSKAIVDDLTLEVPAGQVFGFLGPN
                     GAGKTTTIRMMVGLISISKGDIHICGDSINTDFEKAVSHVGAIVENPEMYKFLTGYQNL
                     QHFARMSPGVTQERVDEAIRLVGLGNRIHDKVKTYSLGMRQRLGVAQAILHRPKLLVLD
                     EPTNGLDPQGIRELRDYLRQLARKEGITVFVSSHLLSEMELMCDRVAIIQSGRLVDIKQ
                     LKNTGEEVQKAEIAFEVNDAEQAYALAGAGRVQGNQLLLHLEREQIAEMNSLLAANGIK
                     VYAIRPVARTLEDQFLEVTGGGVIG"
     gene            1145..1927
                     /locus_tag="PPYC1_RS06070"
                     /old_locus_tag="PPYC1_18230"
     CDS             1145..1927
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369846.1"
                     /locus_tag="PPYC1_RS06070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18230"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_025720453.1"
                     /transl_table=11
                     /translation="MGDFFKLVHNENLKIYLRVRTWIMLGLLAVITAAIPMLISLVSDQ
                     VSVWDGIALTTLFTFFLNTTFTVIVAADSVAGEFTWGTIKLLLIRPWTRSKILLSKYIS
                     VILFSLLGTIILILMVTLSSWVMLSKDAPAGSVPLFSDPISYVTLNFLYSYIALFVTMA
                     FAFMLSAVFRSSALAIGLSLFMMFTKTVYNTIGLFSTDRFEWTKYVLFTHMDLKKYLDM
                     PPGTVSSSLTFSLTVLAAYYVIFIAIAWVVFVKRDVST"
     misc_feature    2080..2096
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.86"
                     /tool="antismash"
     gene            2169..3254
                     /locus_tag="PPYC1_RS06075"
                     /old_locus_tag="PPYC1_18225"
     CDS             2169..3254
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426473.1"
                     /locus_tag="PPYC1_RS06075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18225"
                     /product="AI-2E family transporter"
                     /protein_id="WP_071639876.1"
                     /transl_table=11
                     /translation="MLQNNRFFRLTTGIVMLLLIIYLGTKVSFIFSPLVSLVSLLVVPL
                     MLSFFLYYLLRPIVDVMERRKIKRSISILLIYLVIGVLLFVFSWGVWPTLRDQVTNLFE
                     NAPKLIKSLVDQLSQWRHNQSLRQVLPPGEDPLSQLSDTLNEAFSTLSDYSVKLVSFVS
                     YFFIVLATFPILLYYMLKEGSKFGPKMLNFFPKKYHKDVLEVMEDIDSALSSFIVSRVL
                     INVALGVMMFLGFLIIGLPYALLLAVISIFLNFIPYVGAVAASIPVVIIGFLESPSMAL
                     WSLVVVIAAQQIQDNWLSPIVFGKQLDIHPLTVVILLLVGGDLLGILGIILVIPLYMCG
                     KIVIRKVYQLFLERRVEDIME"
     gene            complement(3294..3755)
                     /locus_tag="PPYC1_RS06080"
                     /old_locus_tag="PPYC1_18220"
     CDS             complement(3294..3755)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369848.1"
                     /locus_tag="PPYC1_RS06080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18220"
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="WP_071639877.1"
                     /transl_table=11
                     /translation="MFKESKKKLSAPAMDTLLANGTSFEGTVEAEANIRIDGHFQGDIR
                     STRTVVIGESAVVRSDIIARDVILAGKVFGSITTEGRLTITPTGELYGNTATAALVISE
                     GGILDGTIQMNRTKDVELSTSADESNDETQSSFSKNKEDSQAALQSEAG"
     misc_feature    complement(3799..3817)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.46"
                     /tool="antismash"
     gene            complement(3801..4832)
                     /locus_tag="PPYC1_RS06085"
                     /old_locus_tag="PPYC1_18215"
     CDS             complement(3801..4832)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426474.1"
                     /locus_tag="PPYC1_RS06085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18215"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_071639878.1"
                     /transl_table=11
                     /translation="MKKGSLNRRMTLLVIRDAQQPPKQLQCSTAAVILVPTLVIASIST
                     LVIGLQIRSSHIISQMETNLAVQSLQMEVTVADKDAAIGRLRQEVMELTNQATNIRERL
                     QRVTELEQQMQQFIRKHGNSSATSNHKKTMTPLSLDASGHIGGELIAVHENTALLTRQA
                     MDDFQEIESLLDTVERTVPRSIQQANAVQQNLERKQAAQLLQTRRLALAEQGNPSVWPV
                     GSRRMTSSFGYRSDPFTGRSAFHSGVDIAGQTGDPVYAAGAGTVLEAASSGARGKCIII
                     QHPDGLQSWYMHLSGMQVAPGDRVHKGQTIGLLGSTGRSTGPHLHFQIVKHNQPVDPLL
                     YVQ"
     gene            4979..6409
                     /gene="cls"
                     /locus_tag="PPYC1_RS06090"
                     /old_locus_tag="PPYC1_18210"
     CDS             4979..6409
                     /GO_function="GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cls"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686424.1"
                     /locus_tag="PPYC1_RS06090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18210"
                     /product="cardiolipin synthase"
                     /protein_id="WP_071639879.1"
                     /transl_table=11
                     /translation="MLWLLLVLIVFIFQTGTILLFEFRKPSKAVAWLFILFCFPLIGFV
                     VYYFVAQDYQKRKMVRKGGSQLFREFRERLWAQSKVIEQVEQMHNPHFKHQERLFNQLI
                     RMSENPLTGCNRTRVLTNGEETFEAMLIAMENAQHHIHVEFYIFRADEIGRKFQEVMIR
                     KAREGVKVRFVVDGVGSYHLPYSFIRTCSEAGVEFHYFLPPFFATLDRRINYRNHRKIV
                     VVDGMIGFVGGINVGDDYLGKYPKVGFWRDTHLQIEGDSVYFLQNAFLSDWKLASGERL
                     MDVNLFPPHTCTGDEEVQILSSGPDQVWDTIQEMCFGALTVAKKRIWITTPYFIPDLGI
                     YEALKLAAVSGVDVKIIIPYQSDSKLVHLASLSYVQELLEAGVEFYQYRKGFIHAKVVI
                     VDDLLGSVGTANMDMRSFFYNFELTAIVFANSALERLSEDFVEDISNSSRIDLNVFRRR
                     PRSQKIAEILTRMLSPLL"
     gene            6605..7549
                     /locus_tag="PPYC1_RS06095"
                     /old_locus_tag="PPYC1_18205"
     CDS             6605..7549
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280287.1"
                     /locus_tag="PPYC1_RS06095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18205"
                     /product="YitT family protein"
                     /protein_id="WP_025720446.1"
                     /transl_table=11
                     /translation="MSVVSKEVQNLSDITDVTGELTKISKIPANPKNKAKRLFQRAAMI
                     IFGAALMAVGLEIFLVPNGVIDGGVTGISIMASKITGYPLGIFLTLLNLPFLLIGYKQI
                     GKTFALSTLFGIIVMSIGTALLHNVSALTPGEPLLGAIFGGVILGVGVGLVIRSGGSLD
                     GTEIVAILVSEKTPFSVGEIVLFVNIFILGSAGFVFGWPNALYSMIAYYIAMKMIDITI
                     EGLDQSKSVWIISEKYRDIGDALTDRLGRGVTYLEGEGGFTGESKKVIFVVITRLEEAK
                     LKSIVEDWDPHAFVAIGNIHDVKGGRFKKKGIH"
     gene            complement(7619..8521)
                     /gene="ligD"
                     /locus_tag="PPYC1_RS06100"
                     /old_locus_tag="PPYC1_18200"
     CDS             complement(7619..8521)
                     /EC_number="6.5.1.1"
                     /codon_start=1
                     /gene="ligD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369853.1"
                     /locus_tag="PPYC1_RS06100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18200"
                     /product="non-homologous end-joining DNA ligase"
                     /protein_id="WP_071639880.1"
                     /transl_table=11
                     /translation="MGQAVKGTITIEGQEIPITNPDKPLWPEAGVTKALYLRKLAVLAP
                     FLLKYCHHRLLTVIRWPHGIHGDFFYQKNAPRPRPDYIETALHDGIEYIVLGKLPQLLW
                     LGNQAALEFHPSLHEAGSKLPCEWMIDLDPSREVEPRIMEAASIVGEVLASLGLDSVPK
                     TSGATGVQIIVPIRTGITFDELRSIGLLVGQFVTEKHPHLFTLERLKKDRGTAIYFDYL
                     QHYQGKTLAAPYTPRARPGATVSTPLTWEEVRQDVSPLDYHLLNIEERLNQVGDLIDKV
                     PPQPVEDVLKHMRTKAHPT"
     misc_feature    8668..8681
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.44"
                     /tool="antismash"
     misc_feature    8669..8682
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.35"
                     /tool="antismash"
     misc_feature    complement(8671..8684)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.74"
                     /tool="antismash"
     gene            8736..10004
                     /locus_tag="PPYC1_RS06105"
                     /old_locus_tag="PPYC1_18195"
     CDS             8736..10004
                     /EC_number="2.8.2.-"
                     /GO_function="GO:0008146 - sulfotransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050656 - 3'-phosphoadenosine
                     5'-phosphosulfate binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309190.1"
                     /locus_tag="PPYC1_RS06105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18195"
                     /product="sulfotransferase"
                     /protein_id="WP_104411462.1"
                     /transl_table=11
                     /translation="MIEKQGGGLVFLLSVPRSGSSLLTAILQNHSRLFATQEMWFLLSL
                     YDLPQSHARPYGGTGILRQFFKGMVPSDVLEQASRSYALEIYNGLLQGTTADMLIDKSP
                     RYYTVLEFIDRLFPTARRLWLIRNPLAIVASFKKVNQLRNGRFQLLEELGSPHFNMKMT
                     DITVGLFRYAHYFATPHPLAYPLRYEQLVSNPTMEIEKLCSFLGIKYEPGMEKYGDFAE
                     TPKSSLFYSMGAGDPFVGEHEQAHQDSVHSWQHLLSKTEIELYCRSIGSRMFRQLGYAE
                     ALEQAEQMTGVRFEDEPDIELLSQRTQQFLQQSGFEWKAGYRMLEDQDADNRELVINAT
                     RHTVPQDLARMQVDQIVSDRRIQSLENRLAHSYEERNRLIAQLQSYQRPNQGLRSRNLF
                     ARKLGRLASVALSSIGKEKGGRT"
     gene            10001..11926
                     /locus_tag="PPYC1_RS06110"
                     /old_locus_tag="PPYC1_18190"
     CDS             10001..11926
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369855.1"
                     /locus_tag="PPYC1_RS06110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18190"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_071639881.1"
                     /sec_met_domain="GATase_7 (E-value: 6.2e-21, bitscore:
                     72.7, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.3e-25, bitscore:
                     88.9, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAIAGIYSFGHESVSTEEGGKMMQALRKYPADRVCAWCEGSIFL
                     GCHAQHVTPESVHERLPFYDELRDLAITADAIIDNRSELFERLGVEQERRQDITDSELI
                     LLAYDKWGVEAASYLIGDFAFVIWDAKEHRLYGARDMTGNRTLYIYQHDRGFAFSTVVA
                     PLLALSSLRKELHEPWLAEFLSIRAMQESVDIGTTAYKHINQLPPAHWFTMEEGKRTLH
                     KYACLDKVEPLRLKTGGEYIEAFREVFTQAVTARLRTHRAVGAALSGGLDSGAVASFAA
                     PSLHLQQKPLHAYSYVPVQDFTDWTPPTLLANERSYIQSTARYVGNIHENYMDFEGKSP
                     FSEIDIWLELMEAPYKYFENSFWIRGFYEKAQEHNVGVLLTGARGNFTVSWGPALDYYA
                     RQFRRLHWLQSFQGLWRYSKLTGRRMSHLLPVMLKKATSLESRSWLRRSNRSPVPSLIH
                     PEFAKRMHVEDIPVLSGTGWMKNADQTRKEKFSNLAIANKNGVVATKLSLQYGLWERDP
                     TGDSRVIRFCLSVPFEQYVQNGRDRALIRTAMRDHLPDDVRLNQRVRGVQPADWLHRML
                     PCWDTFMGELQLMCHDLRAAEYLNIEFIKTAMAKLHDPRPEQASDPNIRLLMHSLIVYR
                     FLCRLN"
     gene            11979..12107
                     /locus_tag="PPYC1_RS06115"
     CDS             11979..12107
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369856.1"
                     /locus_tag="PPYC1_RS06115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_023987454.1"
                     /transl_table=11
                     /translation="MSKKEWQEPTIEVLDINQTMAGKGWKQIDWVSDHDADLHNPS"
     gene            12298..13341
                     /locus_tag="PPYC1_RS06120"
                     /old_locus_tag="PPYC1_18185"
     CDS             12298..13341
                     /EC_number="2.7.1.24"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010349787.1"
                     /locus_tag="PPYC1_RS06120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18185"
                     /product="dephospho-CoA kinase"
                     /protein_id="WP_071639882.1"
                     /transl_table=11
                     /translation="MHDRSANVSWTKYIAFGLRISSELNLPELILAAPEAVEDVVIRQA
                     DLTAWSDQLEQANFVMLDEQFMFQIPGTAIYAVREGKEIEVSIFSGADPDTVRLFVLGT
                     CMGVLLMQRRILPIHGSAVVIGGKAYAFVGESGTGKSTLAAAFRQAGYQMVSDDVIAVK
                     ATASSAVVYPAYPQQKLGLDSLLQLEALRENKHARKRNNIRSLTDGNSLMPQYKDLRML
                     AGELNKYAVPAVDEFFNDPLPLGGVFELVADSPIRALMREGELMAVTEQPLNVLECLHT
                     LLQHTYRRVILPRMGLSEWSFDTAARMARKVEGWRLLRDSSVFTASKVVQRVLDIIRKE
                     EKSYGSH"
     gene            13328..13630
                     /locus_tag="PPYC1_RS06125"
                     /old_locus_tag="PPYC1_18180"
     CDS             13328..13630
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309193.1"
                     /locus_tag="PPYC1_RS06125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18180"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_071639883.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 4.9e-25,
                     bitscore: 85.5, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.1e-16, bitscore: 59.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAATNPAKDHYRVIYGEEVYVSDMDGEKVMMSINTGKYYNLGFTG
                     GRIWELAESGPSLGDIVTVLTNEYEVDEEQCRQQVHSFVAELEREGLLKLLRESV"
     aSDomain        13376..13609
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_PPYC1_RS06125_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="2.80E-27"
                     /identifier="RREFam002.1"
                     /label="PPYC1_RS06125"
                     /locus_tag="PPYC1_RS06125"
                     /protein_end="94"
                     /protein_start="16"
                     /score="85.5"
                     /tool="antismash"
                     /translation="EEVYVSDMDGEKVMMSINTGKYYNLGFTGGRIWELAESGPSLGDI
                     VTVLTNEYEVDEEQCRQQVHSFVAELEREGLLK"
     gene            13632..14117
                     /locus_tag="PPYC1_RS06130"
                     /old_locus_tag="PPYC1_18175"
     CDS             13632..14117
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821220.1"
                     /locus_tag="PPYC1_RS06130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18175"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_071639884.1"
                     /sec_met_domain="PF13471 (E-value: 3.9e-24, bitscore: 83.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIQRLLLLSPEVRRLLPEAWLELGWARLRQRRSFGDYSRVWGIC
                     MEETPWQCDVRQEKCIQQISHAVELASRYTPWRSSCLVQAAAAMTLLGRRKLDCTLYLG
                     TAKNAAGRLAAHAWVRSGPIYVTGKREMEAFTVVGIFGRRVVTDTNTKMEDKGSFLL"
     gene            14146..15642
                     /locus_tag="PPYC1_RS06135"
                     /old_locus_tag="PPYC1_18170"
     CDS             14146..15642
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426482.1"
                     /locus_tag="PPYC1_RS06135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18170"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_071639885.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 2e-81, bitscore:
                     271.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTKSVLELANWNEDQELTLLLSLLGKDVSHWQDKTAATQLREMD
                     WVRFLRLTEHHRVVPTVYLQLKTLNLPFVPAELLRNLQAQYHRNTLRMLHLQAEAERLT
                     RLLIAHGIRVLMLKGPALAQQLYGDVSLRTSKDIDLLIAPDDMDEAEHWMEEAGYASKR
                     GEVRVLGSWKWKDHHASYLHLQKRVEIELHWRLHPDGGGEPSFDELWNCRKIGKAAGTS
                     RQVTLGSADNRTVMTSCMYTLGSEHQFLYLSAHGARHGWFRLRWLVDIDRLAVCAVDWE
                     ALLPMMRRYGGLPAGGQAWALAAALLGTPIPEPMRPVSATRQAHRLALSALAFMQASVP
                     APYPIAHGSGTGRLAPSEPLYSRALAEQAEAAPPNGGASVCDTCGEAAMLATSGVTSIT
                     EDASNDDHSPMSTATSCAPITPAAASSQVMTRNTAAAHQPVSRTYLLSLKEPRHRLWYL
                     ISRLFPSTGDSAVFPLPRQLHFLYIPLRPFLWLKRRFSKH"
     gene            15787..17592
                     /locus_tag="PPYC1_RS06140"
                     /old_locus_tag="PPYC1_18165"
     CDS             15787..17592
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821218.1"
                     /locus_tag="PPYC1_RS06140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18165"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_071639886.1"
                     /transl_table=11
                     /translation="MVHLRLYMTKLYSVNGGALFLNIGCMIMVSLLEGFGIYMLVPMLA
                     AIGVFVGHSGMPFLSGGLEHFLAFIPKSWLLPGMLMVFIVLLTGQAMLQRYQSILNSRI
                     QQRFMRSLRIDVYTSFMKAQWAFYLRQRKSDFSHVMTTELARVSQGTNLLLQLTTAVMF
                     TMIQIALAFWLSPSLTGLVFLSGLGLFVVFRRSIRNAKQLGDRTTELSQVYFAGITDHM
                     NGMKDIKSNLLEAANIHWFRSLTQRMEDNTTQFVRQNATTQFFHRTAAAVFVACVIFIS
                     LQWLHVTPEKLIVLILIFSRLWPRFALIQASLEYIMSMISAFESVTKVQQECEAFTDPS
                     LIVSASVRQPLSLRHGIECSHLDYRYDGAAESALRNINLFIPARGMTAIVGKSGAGKST
                     MVDVLMGFLRPTGGQITIDGLVLDDELLLQWRQSFGYVSQDPFLFHATVRENLMLADKD
                     ASEQQLWEALHFAAADNFVSRLPEGLDTVIGDRGIRLSGGERQRLVLARAVLHHPSVLI
                     LDEATSALDGEHEAAIQAALERMKGQMTLIVIAHRLSTIRHADQIVVLDQGEVIQQGNY
                     HQLEQEERGAFSQLLSYQSSVTATP"
     gene            complement(17615..18529)
                     /locus_tag="PPYC1_RS06145"
                     /old_locus_tag="PPYC1_18160"
     CDS             complement(17615..18529)
                     /GO_function="GO:0045027 - DNA end binding [Evidence IEA]"
                     /GO_process="GO:0006303 - double-strand break repair via
                     nonhomologous end joining [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309197.1"
                     /locus_tag="PPYC1_RS06145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18160"
                     /product="Ku protein"
                     /protein_id="WP_071639887.1"
                     /transl_table=11
                     /translation="MHTVWKGAISFGLVHVPVKMFSATEDKDISMRYIHKECGSPLSYV
                     RKCPVCDKEVEWEEIGKGYEYEKGKFVMFDKEELEQVSGQADKNIVILDFVDLQEIDPI
                     YFQKTYYLSPDQAGSNAYKLLMNAMKDTGKIGIAQISIRSKSSLAAIRVLDECLAVETM
                     FYPDEIRPIAQVPNLPGQEEVKEKELTMAKMLIEQLSTPFDAAKYTDQYRERLLDLIQH
                     KVAGEEVRIAPTQPQTNVVDLMAALQASIEAVQPVVTDPGPAAKKRPARKPAAPSAQQA
                     VAGENISPTPAKKKRSTAKRKET"
     misc_feature    18706..18723
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.46"
                     /tool="antismash"
     misc_feature    complement(18851..18864)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.9"
                     /tool="antismash"
     gene            18942..19340
                     /locus_tag="PPYC1_RS06150"
                     /old_locus_tag="PPYC1_18155"
     CDS             18942..19340
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002144149.1"
                     /locus_tag="PPYC1_RS06150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18155"
                     /product="RidA family protein"
                     /protein_id="WP_071639888.1"
                     /transl_table=11
                     /translation="MKYEKITRKNPAGMPKPVGNYTHITKVPRNSELFVTSGQVGVDQN
                     GQFPESFNLQISNTFNNIKSVLDAEQLTADNIIKVNVWATEQIDWDYMYSQWEKLFGND
                     YPAMTIGYLTALGLPEIKIEIEIWAAKA"
     gene            19675..19914
                     /locus_tag="PPYC1_RS06155"
                     /old_locus_tag="PPYC1_18150"
     CDS             19675..19914
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369863.1"
                     /locus_tag="PPYC1_RS06155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18150"
                     /product="hypothetical protein"
                     /protein_id="WP_071639889.1"
                     /transl_table=11
                     /translation="MSGKSYPQQIRHRVGQSQIAFRGPAGGEQDALPPEFALSHGIRPP
                     FPVAVAHVDLEAVVSTSPSHGIPSLDVERIIDED"
     gene            19971..20150
                     /locus_tag="PPYC1_RS06160"
                     /old_locus_tag="PPYC1_18145"
     CDS             19971..20150
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309199.1"
                     /locus_tag="PPYC1_RS06160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18145"
                     /product="H-type small acid-soluble spore protein"
                     /protein_id="WP_023987462.1"
                     /transl_table=11
                     /translation="MNVERAKAIYDSSENIAVQLDGKPIWIEHVDQANGMATVQIGSRP
                     GNTQTVRVDRLEEQ"
     gene            complement(20391..21047)
                     /locus_tag="PPYC1_RS06165"
                     /old_locus_tag="PPYC1_18140"
     CDS             complement(20391..21047)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369865.1"
                     /locus_tag="PPYC1_RS06165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18140"
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="WP_071639890.1"
                     /transl_table=11
                     /translation="MNNREFIARRIAQEFKNGEVVNLGVGLPTMVVDYIPENIHIMLQA
                     ENGILGVGPKAAQGKERLDCIDSGGNYVTTMEGACFFDSALSFSIIRGGHVDITVLGAL
                     EVDEKGNLASWMIPGKKVPGMGGAMDLVVGAKRVIVAMEHVNKNGAPKILKQCKLPLTA
                     VNVVKTIVTEKAVIDVIPGKGLMLKEIAPGLSVEDVQLATEAKLMVSPHLKAIAV"
     gene            complement(21044..21709)
                     /locus_tag="PPYC1_RS06170"
                     /old_locus_tag="PPYC1_18135"
     CDS             complement(21044..21709)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429861.1"
                     /locus_tag="PPYC1_RS06170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18135"
                     /product="CoA transferase subunit A"
                     /protein_id="WP_071639891.1"
                     /transl_table=11
                     /translation="MNNKVISAEEAVKKIKDGDTVMVGGFLAGGFPEDLVRALVDTNPA
                     SNLTIISNDTGTPELSIYKLVKSGRVKRIFASYIGSNPETGRLLMTKEAEVQLFPQGTL
                     AEKIRAGGAGLGGVLTPVGVGTVVEEGKKKIEIDEREYLLELPLKADVALIRAHKADEA
                     GNLVINGSSRNFNMVMATAAEYVVAQIDEYVKTGEIDPNHVNVPGIFVDAIVKVGENA"
     gene            complement(21751..22491)
                     /locus_tag="PPYC1_RS06175"
                     /old_locus_tag="PPYC1_18130"
     CDS             complement(21751..22491)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686439.1"
                     /locus_tag="PPYC1_RS06175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18130"
                     /product="acetoacetate decarboxylase"
                     /protein_id="WP_071639892.1"
                     /transl_table=11
                     /translation="MNQKDVLSLQSMPAASGSYGRPPCRFINREFLIITYESDPAAIRQ
                     AVPEPLQPDGSNTVSYEWIKMPDSSGLGSYEESGIVIPCTFHGEPCNFVAQMYLDNAPA
                     ILGGREIWGFPKKWAKPRLIVEETETLTGTLHYNNVLVATGTMPFKYNILDEKETAKAI
                     AKTQVNLKLIPDVDGTPKIAQLVAYNLENVTVKGAWSGPARLSLIPHVNAPVADLPVKA
                     YIGGKHFIADLTLPYGRVLYDYLQ"
     gene            complement(22547..23731)
                     /locus_tag="PPYC1_RS06180"
                     /old_locus_tag="PPYC1_18125"
     CDS             complement(22547..23731)
                     /EC_number="2.3.1.9"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429859.1"
                     /locus_tag="PPYC1_RS06180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPYC1_18125"
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="WP_071639893.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.6e-05, bitscore:
                     22.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVALVSPLRTAVGSFNKTLAPLSAPELGATVMTACLQQSKLEP
                     SLIDQIYLGNVLQAGNGQNPARQAALKAGIPIDVPETTINTVCGSGLHAVALAYNSILA
                     EQGNIVLAGGMESMSNAPYLLRNARNGYKLGNGELVDSLVADGLTCPINHYHMGITAEN
                     VAEKYGISRLEQDEFAYQSQIKAVEAKNKKLFEEQIVPVMIKNKKETISFTEDEHIRGN
                     TTKEKLSQLKPAFKENGTVTAGNASGINDGAAAMLVVSEDKCKEHALKPLAYIKGYSLV
                     GVDPAYMGMGPVKAISSLLKQQGMSIDDIDLFEINEAFAAQALAVLKELGINPEKVNVN
                     GGAIAIGHPVGASGARVLVTLVHEMVRRSSRYGIASLCIGTGMGIAMLVENALI"
     misc_feature    23723..23736
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.09"
                     /tool="antismash"
     misc_feature    complement(23926..23939)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.77"
                     /tool="antismash"
     misc_feature    24052..24066
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 24.83"
                     /tool="antismash"
     misc_feature    24059..24073
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.75"
                     /tool="antismash"
     misc_feature    complement(24084..24097)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.68"
                     /tool="antismash"
ORIGIN
        1 gtattacggt cactcagcat tacaagaccc gattcggcaa ttttgatatc gtacagcctt
       61 gttatttgac gcaggaagat gagaagtggc gggtgctttg gatatacaag gacaaggaat
      121 agaggttgcg tggtgtttct aaaaggttaa atatggtaca atacttccaa aaccggaaat
      181 gtacagtaaa atggatcaca gcttcactcc ggatggaagg agtttcaaag catgcagcaa
      241 gcgacaggac aggttcccgt catacgtatg gagggtgtga gtaaaatcat ttcctcaaaa
      301 gcgatcgtgg atgatctgac gctggaggtt ccggcggggc aggtatttgg tttccttgga
      361 cccaatggtg cgggtaaaac gaccaccatc cgtatgatgg ttggcctgat ttcgatcagc
      421 aagggcgata ttcatatttg tggagacagc atcaataccg attttgaaaa ggctgtttcc
      481 catgtcggcg cgattgttga gaacccggaa atgtacaagt ttttgacagg ctatcaaaat
      541 ttgcagcatt ttgcgcgaat gtctcctggg gtaacacaag agcgcgtgga tgaagcgatt
      601 cgtctggtgg gactcggaaa ccgaattcat gataaagtaa aaacctattc gctcgggatg
      661 cggcagcgac ttggggtagc tcaggcgatt ttgcatcgac cgaagctgct tgtgctggac
      721 gagccgacca atggcttgga tccgcagggt attcgtgaac tgcgggatta tttgcgtcaa
      781 ttggcccgta aggaaggaat taccgtattc gtatcaagcc atttgttgtc cgagatggag
      841 ctgatgtgcg accgtgtagc tattattcag agcggacggc tggttgatat caagcaactg
      901 aagaatacag gggaggaagt gcagaaggcg gaaattgctt ttgaggtaaa tgatgccgaa
      961 caagcttatg cgcttgctgg agcagggcgc gtccaaggta atcaactgct gcttcacctg
     1021 gagcgggaac agattgcaga gatgaacagc ctgctggctg caaatggcat taaagtatat
     1081 gcgattcgcc cggttgcccg tacgctggaa gatcaatttt tggaagtgac gggaggcggg
     1141 gtcattgggt gatttcttca agctggtaca taacgaaaat ctgaaaattt acctgcgtgt
     1201 gcgcacatgg attatgctgg ggctgctggc ggtcattact gctgcgattc ctatgctgat
     1261 ttccctggtt tccgatcagg tcagtgtgtg ggatgggatt gcgttgacga cgttatttac
     1321 atttttcctc aatacgacgt ttacggtcat tgtagccgct gattcggtgg ctggtgaatt
     1381 tacttgggga acgattaaac tgctgctcat ccgaccttgg actcgcagca aaatattgtt
     1441 gtccaagtat atatccgtga ttttgttcag tttgctcgga acgatcattt tgattttgat
     1501 ggttacgctg tcctcatggg tgatgttatc caaggatgca ccagcgggtt ctgttccgct
     1561 gttcagtgat ccgatatctt acgtaacgct gaacttcttg tatagctata tcgccttatt
     1621 cgtgacgatg gcctttgctt ttatgctgtc cgctgttttc cgttccagtg ccttggcgat
     1681 tgggctgtca ctgttcatga tgttcaccaa aacagtttat aacacgattg gcttgttcag
     1741 cacagatcgt tttgaatgga ccaaatacgt tctatttacg catatggatc tgaaaaaata
     1801 tttagatatg ccgccgggta cggtaagttc cagtctaacc ttttcgctca ccgtgctggc
     1861 tgcatattat gtgattttta tcgccattgc ctgggtggtt ttcgtaaaac gggatgtttc
     1921 aacctaaatc gaagtgtctt agagttacat aaaggacgtt caaatgccta gcatttggac
     1981 gtccttttgt tatttaagga ttttgcaaaa tcctcattta agactatttt atcctgtatt
     2041 taggttattt ttgctacaca ttctgcatac aggggtatat tgtaatctat tttcagcaag
     2101 aatcaatcaa tagggtcatt ttgcgtttaa agaggtagag agaaacagaa cagagggggc
     2161 cgcatgatat gctgcaaaat aatcgttttt ttcgtctgac tacaggtatc gtcatgctat
     2221 tactcatcat ttacttgggc accaaagtaa gttttatatt tagtcctctc gtatccttgg
     2281 tcagcttgct ggtggtaccg ttaatgctat cttttttcct ctattattta ttgaggccga
     2341 ttgtagatgt aatggaacgg agaaaaatca aacgatctat ctccatcttg ctgatttatt
     2401 tggtcattgg agtgttattg tttgttttct catggggtgt gtggcctacg ctgcgtgatc
     2461 aagttaccaa tttatttgaa aatgcgccga agctcattaa aagtctggtt gatcaattga
     2521 gccaatggcg gcataatcaa tccttgagac aagtactgcc tccgggtgaa gacccgctgt
     2581 cacaactgtc agatacgttg aacgaagctt tttcgacact gtctgattat tcggtaaagc
     2641 tggtatcgtt cgtgtcctat ttttttattg tattggctac ctttccaata ttgctctatt
     2701 acatgctgaa ggaagggagc aagtttggcc ctaaaatgct aaacttcttt ccaaaaaaat
     2761 atcacaagga cgtattggag gttatggaag atatcgatag tgcactcagc agctttatcg
     2821 tgagtcgggt gctgattaat gtcgcgttgg gtgtgatgat gtttcttgga tttttaatta
     2881 ttggtttgcc ttatgccttg ctgctcgccg ttatttcgat ttttcttaat tttattccct
     2941 atgtgggggc agtggctgct tctatacctg tggttattat tggatttctc gaatcacctt
     3001 cgatggcact ctggtccctg gtcgtggtga tcgctgcaca gcaaattcag gataattggc
     3061 tgtcacctat agtttttggc aagcagctgg atattcatcc gttgactgtc gttattttac
     3121 tgttagttgg tggcgacctg ctcgggattc tgggtatcat tttggtgatt ccattgtata
     3181 tgtgcggaaa aatcgttata cgcaaggtgt accaattatt tttggagcgc agagtggagg
     3241 atattatgga atgaatggaa aatgcactgg atttaaagga gtatatactg actttatcct
     3301 gcttcggatt gcagagcggc ttggctgtcc tccttgtttt tgctgaaact agattgggtt
     3361 tcgtcgtttg actcatccgc agaagttgac aactctacat cctttgttcg gttcatttga
     3421 attgtgccgt ccagtatacc accttcagaa atgaccaatg cagcggttgc cgtatttccg
     3481 tacagttcac ctgtcggcgt aatggtcagt cgtccttctg tagtaatgct gccgaacacc
     3541 ttaccggcaa gaatgacgtc tcgtgcgatg atgtccgaac gtacaacagc agattctcca
     3601 atgacgacag tacgagtgct gcggatatcg ccctgaaaat gaccgtcgat ccgaatattg
     3661 gcctctgcct caactgtacc ttcaaagctg gtgccattag cgagcagtgt atccatagct
     3721 ggggcggaga gctttttttt ggattccttg aacatgatgg ttttccccca atcttttatt
     3781 gtaaagattt tgaaaaatcc ttattgtaca tacagtaatg gatcgacagg ttggttatgc
     3841 ttgacgatct gaaaatgaag gtgaggtcct gtgcttctcc cggtacttcc cagcagaccg
     3901 atggtctgtc ctttgtggac acgatccccc ggagccacct gcatgccgct caggtgcata
     3961 taccagctct ggagcccgtc aggatgctgg atgatgatgc acttgccgcg ggctccgcta
     4021 gaagcagcct ccaagacggt gcccgcccca gctgcataga caggatcacc ggtttgtccg
     4081 gcaatgtcca cgcctgaatg aaaggcagat ctacccgtaa aagggtcgct gcgatagccg
     4141 aagctggagg tcattcgccg tgaacctaca ggccaaacgg agggattccc ttgctcggca
     4201 agagccagcc tacgagtctg gagtagctgt gcagcttgtt tgcgctccag attttgctgt
     4261 acggcatttg cttgctgaat agagcgggga accgtacgtt ccaccgtgtc caacagagat
     4321 tcgatctcct gaaaatcatc cattgcctgg cgagttagga gggcagtatt ttcatgcact
     4381 gcgatcagct cacctccgat atggccggaa gcatccaagg agagcggcgt catggtcttt
     4441 ttatggttac ttgtggcaga tgagtttccg tgttttcgaa tgaattgctg catttgctgt
     4501 tccagctccg ttacacgctg gaggcgttca cgaatattgg tggcttgatt cgtcagctcc
     4561 atgacttcct gccgtagtcg cccaatggct gcatccttgt ccgctaccgt gacctccatc
     4621 tgcaaactct ggacagcaag attcgtttcc atttgggaga taatatggga agaacggatt
     4681 tgcagcccga tcacaagtgt agagatagat gcgatcacaa gagttgggac gagaatgaca
     4741 gcggctgtag agcattgtag ctgcttgggt ggttgctgtg catcccgaat aacaagcagg
     4801 gtcatccggc gatttaggct tccttttttc ataatcgctc ctttccggac atcgctccta
     4861 tagtgcttgg ttactatcta ttcagcttaa gaggcaaaca tgtcaaaaaa attggagctt
     4921 agtataaaac gtagatgagg attttccaaa atcctgagat atataaggag gcttagacat
     4981 gctgtggttg ctgttggttt taattgtttt tatttttcag accgggacga tcctgctctt
     5041 tgaatttcgc aagccgtcca aagcggtagc ctggcttttt attttgtttt gcttcccgct
     5101 cattggcttt gtcgtgtact actttgttgc acaggattat cagaagcgca aaatggttcg
     5161 aaaaggggga tcgcagctgt ttcgtgaatt tcgcgagcgt ctgtgggcgc aatccaaggt
     5221 gattgaacag gtggagcaaa tgcataatcc tcatttcaag catcaggagc gtctgtttaa
     5281 ccagttaatt cgtatgtcgg aaaacccgtt gactggatgt aatcgcacac gtgtgctgac
     5341 gaacggtgaa gaaaccttcg aggctatgct gatagcgatg gaaaatgcgc aacatcatat
     5401 ccatgtggag ttttacatat ttcgggccga cgaaatcgga agaaaatttc aagaggtcat
     5461 gatccgcaag gcacgtgagg gagtaaaggt acgattcgtt gtggacggtg taggaagcta
     5521 ccatttgccc tattccttta ttcgtacctg tagtgaggcg ggagtggaat ttcattattt
     5581 tctacctccg tttttcgcca cgttggaccg ccggattaac tatcgcaatc acaggaaaat
     5641 cgtggtggtg gacggcatga tcggatttgt gggggggatt aatgtaggcg acgattatct
     5701 cggaaaatat cccaaagtgg gattttggag ggatacgcat ttgcagattg aaggagatag
     5761 cgtctatttt ctgcaaaatg catttcttag cgactggaag ctggcctcag gggaaaggct
     5821 gatggatgtg aatttatttc ctccacatac ctgcaccggg gatgaggaag tacagatttt
     5881 gagcagcggt cccgatcagg tttgggatac gattcaggaa atgtgttttg gagcgctcac
     5941 agttgccaag aagcggattt ggattacgac gccgtatttt attcccgatc tggggattta
     6001 tgaggcgctc aagctggcag cagtcagtgg cgtagatgtg aaaattatta ttccctacca
     6061 atccgattca aagctggttc atctggcgtc tttatcctat gtgcaagaac tgctggaggc
     6121 aggggtggag ttctaccaat atcgaaaagg atttattcac gccaaagtgg tgattgttga
     6181 tgatttactc ggctcggtcg ggaccgccaa tatggacatg cgcagctttt tctataattt
     6241 tgagttgacc gctatagttt ttgctaattc agcgctggaa cggctttcgg aagattttgt
     6301 agaggacatt tccaactcct cacgcataga tttaaacgtg ttccgcagac ggcctcgatc
     6361 tcagaaaata gctgaaattc taactcgcat gctctctcca ctcctttaaa ggcggttttc
     6421 gccgttttta tcgatataat cccgctttat tgtgatttat gtgctctttg ctaacttttt
     6481 tgcgcaaaat cacagtttta tggtatacta ttcatataac acaagcgcgg taaaggagag
     6541 gggactgcgg atagcagccc ctttttcggt ccaatatacc atactgtaac ggggggattt
     6601 atatatgagt gtagtgagca aggaagttca aaatctgtct gatatcacag atgtaaccgg
     6661 agagttgacc aagatcagca aaattccagc taatccgaag aacaaagcaa aacgcctgtt
     6721 tcagcgtgcg gccatgatta ttttcggtgc ggcgcttatg gcagtgggcc tcgaaatatt
     6781 tctggttcct aacggcgtta ttgacggagg cgttacaggt atttccatca tggcctccaa
     6841 gattactggc tatccactcg gcattttcct gaccctgttg aaccttccat ttttacttat
     6901 cggatacaaa caaatcggta aaaccttcgc tttatccaca ttatttggca ttatcgtgat
     6961 gtccatcggt accgcgttac ttcacaatgt aagtgcattg actcctggcg aaccactatt
     7021 gggtgctatc tttgggggcg tcattctcgg cgttggggtg ggtcttgtga ttcggtctgg
     7081 cggctcgctg gatggaacag agatcgtagc tattctcgtc agtgaaaaaa ctcctttttc
     7141 ggtcggtgag atcgtactgt tcgttaatat cttcattctg ggaagtgcag gttttgtgtt
     7201 cggttggccg aatgccctgt attccatgat tgcttattat atcgccatga aaatgattga
     7261 tattacaatt gagggtctgg atcagtccaa atcggtctgg attattagtg aaaaataccg
     7321 tgatatcggg gatgccctga cagaccgtct tggacggggc gtaacttatc tggaaggtga
     7381 aggcggcttt acgggcgaaa gcaagaaagt gattttcgtt gtcattaccc gactggagga
     7441 agctaagctg aagagcatcg ttgaagattg ggacccgcac gctttcgttg cgatcggtaa
     7501 cattcacgat gtgaagggcg gacgctttaa gaaaaaagga atacactagc gcaaggggac
     7561 aatttctcag cctaatggct gcggggttcg tccccttttt tgttcttcca agcattgatc
     7621 aggttgggtg tgccttggtg cgcatatgct tgaggacgtc ttctacgggc tggggaggaa
     7681 ccttgtcgat caagtcgcct acctggttta gtcgttcctc aatattcagc aaatggtagt
     7741 caagtggtga tacatcttgc cgtacctctt cccatgttag cggagtggag accgtagcgc
     7801 cggggcgtgc ccgcggggta taaggagcgg ccaaagtttt cccctgataa tgctgcaaat
     7861 aatcaaaata gatggctgtt ccacgatcct tctttaaccg ttcgagtgtg aacagatgcg
     7921 ggtgcttttc tgtcacaaac tgtccaacta atagcccgat gctgcgaagt tcgtcgaagg
     7981 ttatgcctgt acggatcgga acgataattt gtacacctgt ggccccagat gttttaggga
     8041 cggaatccaa accaagcgaa gctagtactt caccgacaat agaggctgcc tccataatac
     8101 gtggctccac ctctctggat ggatcaaggt caatcatcca ttcacagggc agcttgcttc
     8161 ccgcttcatg cagagagggg tggaattcca acgcagcttg attaccaagc cagagaagtt
     8221 gtggcaattt gccgagcacg atatattcaa taccatcatg cagagcggtt tcaatatagt
     8281 ccggccgagg acgtggggca tttttctgat aaaaaaaatc accgtgaatc ccatgtggcc
     8341 agcgaatgac ggtcagcaga cgatgatggc aatatttgag caggaaggga gctaataccg
     8401 ccagcttgcg aagatatagc gccttagtca cgcctgcttc aggccacagt ggtttatccg
     8461 ggtttgtgat aggaatttcc tggccttcaa tggtaatggt acctttaacg gcttgtccca
     8521 tagtgctatc ctcctttgtc taacatgcag caaaatcttt atttacagac tgattgttga
     8581 acttatagat ctacatatgg attaacatga acgtgaagtg ctgaatttat ccatcaaagg
     8641 gattgacaag atacattatg tatcataaat ttataataaa aaatacgata tgtatctatt
     8701 aaagtgtctt gagcagaggt agaggaggag tttgcttgat tgaaaagcaa ggcggagggc
     8761 tggtattcct gttaagtgtc cctcggagtg gaagctcgct gcttaccgcc attttgcaaa
     8821 accattcccg cctgtttgcc acacaggaaa tgtggtttct gctcagttta tatgatcttc
     8881 ctcagtcaca tgcacggcca tatggaggaa caggcatact tcggcaattt tttaaaggca
     8941 tggttccctc cgacgtattg gagcaggcct cccgttcgta tgcacttgaa atatataatg
     9001 gtctgcttca aggaacaaca gcagatatgc ttatcgacaa atctccgcgt tactatacgg
     9061 tgctggaatt tatagaccgt ttattcccta ctgcccgcag gctgtggctt atccggaatc
     9121 ctttggccat cgtggcctca tttaaaaagg tcaatcagct acggaatgga cgttttcaac
     9181 tgctggaaga actggggagt ccgcatttta atatgaaaat gacggatatt acagttggtt
     9241 tgttccgtta tgctcattat tttgctacac ctcatccact tgcatacccg cttaggtatg
     9301 aacagctcgt atccaatcca acgatggaga tcgagaagct gtgcagtttt ctggggatca
     9361 agtatgagcc ggggatggaa aagtacggag actttgcgga gacgcccaaa tccagtcttt
     9421 tttatagtat gggagcgggt gatccattcg taggagagca tgagcaggcg catcaggatt
     9481 cggtacatag ctggcaacat ttgttgagta aaacggaaat tgagctatat tgcagaagca
     9541 ttgggtcccg catgtttagg cagcttggtt acgcggaagc gttggagcag gctgagcaga
     9601 tgactggagt ccgctttgaa gatgagccgg atatagaact gctgagtcaa cgtacacaac
     9661 aatttctcca acaaagcggc tttgaatgga aggcaggtta tcggatgctg gaagaccagg
     9721 atgcagataa cagagaactt gtgataaatg caacccgtca tactgtacct caagatctag
     9781 caaggatgca ggtggaccag atcgtgagcg atagacggat tcaatcactg gaaaacaggt
     9841 tggcacatag ctatgaggag cggaaccgtc ttatcgctca gctccaaagc tatcaacgcc
     9901 caaatcaagg tctccgatct cgcaacctct ttgcccgtaa gctcgggcgc ttggcgtctg
     9961 tagcgttatc aagtatagga aaagaaaaag ggggaagaac gtgagtgcga ttgccggaat
    10021 ctatagcttt gggcatgagt ccgtaagcac cgaagaaggc gggaaaatga tgcaagccct
    10081 gcgaaaatat cccgctgacc gcgtatgcgc ttggtgcgaa ggctcaattt ttttgggttg
    10141 tcatgctcag catgtgaccc cggaatctgt tcatgagcgt cttcccttct atgatgagct
    10201 aagagatttg gcaatcacag cggatgcgat tattgacaat cgttccgagc tgtttgaacg
    10261 gctgggagtt gagcaggaac ggcggcaaga tatcacggac agcgagctga ttttgctggc
    10321 atatgacaaa tggggagtgg aagcagccag ttatctgata ggtgattttg cctttgtcat
    10381 ttgggatgcc aaggaacatc gattatatgg tgctcgagat atgacaggaa atcgtacgct
    10441 gtacatctac caacatgatc gaggattcgc gtttagcacg gtagtcgctc cacttttggc
    10501 cctgtcctct ctgcgaaaag aactgcatga accgtggctg gccgaatttt tgtccatccg
    10561 tgccatgcag gaatccgtcg atatcggaac gaccgcatac aagcatatca accagcttcc
    10621 tcctgcacat tggttcacta tggaggaggg gaagcgaacc cttcataaat atgcatgtct
    10681 ggataaggta gagccactgc ggctcaaaac aggaggcgag tacatagaag ctttccgcga
    10741 ggtgttcaca caggcggtca ctgcccgact acggacgcat cgcgctgtag gggctgcctt
    10801 gagcggaggg ctggattctg gggcggttgc cagctttgcc gcgccatcgc tgcacttgca
    10861 acaaaagccg ctgcatgcct acagctatgt gcctgttcaa gattttacag actggacacc
    10921 gcctacattg ctggcgaacg aacgaagcta tattcagtct acggctcgct atgtaggaaa
    10981 cattcacgag aattatatgg attttgaggg gaaaagtccg ttttcagaaa ttgatatttg
    11041 gctggaactc atggaagcac cctacaaata ttttgaaaac tctttctgga tcagaggttt
    11101 ttatgaaaaa gcacaggagc acaatgtcgg tgtactattg accggggcac gaggcaattt
    11161 taccgtatcg tggggtcctg cactagacta ttatgcccgg cagtttcgtc gtttgcactg
    11221 gttgcaatcc tttcagggat tgtggcggta cagcaagctt acgggcaggc gtatgtctca
    11281 tctactccct gtgatgttga aaaaagcgac ttcgcttgaa tctcgttcat ggctgcggcg
    11341 tagcaatcga agtcccgttc cttcactgat ccacccggag tttgccaaac ggatgcatgt
    11401 agaagatatt cctgtattga gcggaacagg ctggatgaaa aacgccgatc agacgagaaa
    11461 agagaaattt tcgaatttgg cgattgctaa caaaaatggt gtggtcgcga ccaaactttc
    11521 actacagtat ggcctgtggg aacgtgatcc gaccggagac agccgagtga ttcgcttttg
    11581 cttatcggtg ccttttgaac agtatgtgca aaacggtcgg gaccgtgccc tcattcgtac
    11641 tgccatgcgt gatcatctac ctgatgacgt tcggttgaac cagcgggtac ggggtgtaca
    11701 gcctgcagat tggttacatc gaatgcttcc ttgctgggat acgtttatgg gagagcttca
    11761 actgatgtgt catgatttac gagccgccga atatctcaat attgagttta ttaagacggc
    11821 tatggcgaaa cttcacgacc cccgccctga gcaggcgtct gatccgaata tacgactact
    11881 aatgcatagc ctgatcgtgt accgttttct ctgtagattg aactgatcga acctatccgg
    11941 tcagacagtc cgccattcgt tggaggggag gtgatgagat gagtaaaaaa gaatggcagg
    12001 aaccgacgat agaggtgctg gatattaacc agactatggc gggtaaaggc tggaaacaga
    12061 ttgactgggt gtctgaccac gatgccgatc ttcataatcc aagctaacac atggttatac
    12121 atgcagccga tgttgggctg gaagcgaaaa aactggtccg ataacgacta aatgaacgag
    12181 aatagcataa tccattggac tcgtattcaa tacaaagccg tctttatttc ttcgggttag
    12241 aggtattgcc caagaaataa agacgggatt tttaaggaca gaggagtgag tcctatcgtg
    12301 catgacagga gtgcaaatgt cagttggacg aaatatatag cctttggact caggatttcc
    12361 agtgagctta atctgcctga gctgatcctg gcagcaccgg aagcagtaga ggatgtagtc
    12421 attcgacaag ctgatttaac tgcatggagt gatcagctgg agcaggccaa ttttgtgatg
    12481 ctagatgagc aatttatgtt ccaaatacca ggcacggcca tttatgccgt cagggaaggc
    12541 aaggagatcg aggtaagcat attctccggg gccgatcctg acaccgtgcg gctgtttgta
    12601 ctgggtacat gcatgggtgt tctgctgatg caaagacgaa tattacctat tcacggaagt
    12661 gcggtcgtca tcggggggaa ggcctacgca tttgtgggtg aatcgggtac gggcaaatcg
    12721 acactggctg ctgcttttag gcaggcaggt tatcagatgg ttagtgatga cgtgattgct
    12781 gtaaaagcta cggcttcctc agccgtcgtg tatccagctt atccgcagca aaagctgggg
    12841 ttggatagct tgctccaact ggaggctttg cgggagaaca agcatgcacg caaaagaaat
    12901 aacatacggt ccctaactga tggcaattct ttaatgccac aatacaaaga tctgcgtatg
    12961 cttgcaggtg agctgaataa atatgccgta cccgccgtag atgaattttt taacgatccg
    13021 ctgcccttag ggggcgtatt cgagcttgtg gcagattctc caatccgtgc gttgatgcgc
    13081 gaaggggagc taatggcggt tacggaacag cccttgaacg ttctggagtg cttgcataca
    13141 ttactacaac atacatatcg tagggtgatt cttccgcgaa tgggtttgag tgaatggtcg
    13201 tttgatacag cggctaggat ggctcgtaaa gtagagggct ggcggctgct gagggatagt
    13261 tccgtcttta ctgcgtccaa ggttgtacaa cgggtacttg atatcattcg taaggaggaa
    13321 aagagttatg gcagccacta atccagctaa agaccattat cgcgtcattt acggtgaaga
    13381 ggtctatgtc agtgatatgg acggagaaaa agtgatgatg agcattaaca ctggtaaata
    13441 ttataactta ggcttcacag gaggacgaat ctgggaactg gcagaatccg gtccttccct
    13501 tggcgatatc gtaactgtcc tgacgaatga atatgaggtg gacgaggaac agtgcagaca
    13561 gcaggtacat tcctttgtgg ctgagttgga gcgggaagga ctgttaaagc ttctacggga
    13621 gtcggtataa catgcggata caacggcttc ttctcctgtc tccagaggtt aggagattgt
    13681 tgccggaagc ctggttggag ctgggatggg cgaggctgcg ccagcgtcgt tcttttgggg
    13741 attactcaag ggtttggggc atatgtatgg aagaaactcc atggcagtgt gatgtcaggc
    13801 aggagaagtg cattcagcag atttcgcacg ctgtagagct ggcaagccgt tatactcctt
    13861 ggcgcagtag ttgtcttgta caagccgctg cggcgatgac gttgctgggg cgcagaaaac
    13921 tggactgcac gctgtatctg ggcacagcca aaaatgccgc tggacgcttg gccgcacatg
    13981 catgggtacg tagcggaccg atttatgtta cggggaaacg ggagatggag gcatttacgg
    14041 tggtggggat attcgggaga cgagttgtga cggatacaaa tacaaagatg gaagataaag
    14101 gtagtttttt gctttaatgc gatgagacaa gaaggagaag aatgcatgcc caccaagtct
    14161 gttttggaac ttgcgaattg gaatgaggat caagaattaa cgttgttact ctctctattg
    14221 gggaaagacg tttctcattg gcaggataag actgctgcta cccagctgcg tgagatggat
    14281 tgggtccgct ttttacgtct gaccgagcac catcgagtgg tacctacggt gtatctccaa
    14341 ctgaaaacat tgaatcttcc gttcgttccc gcagaattgt tgcgaaacct tcaggcgcag
    14401 tatcatcgaa acacgcttcg catgctccat cttcaagcag aagccgagcg tctaaccagg
    14461 ctgctcatag ctcatggaat tcgtgtgctt atgttgaagg gtcctgctct agcgcagcaa
    14521 ttgtacgggg atgtttctct gcgtacctcc aaggatatag atttactcat tgcccctgac
    14581 gatatggatg aggctgagca ttggatggag gaagccggat atgcgtccaa gaggggagaa
    14641 gtgcgtgtcc ttggcagttg gaaatggaag gaccatcatg catcctacct ccatctgcaa
    14701 aaacgggtag agattgagct gcattggcgg cttcacccgg atgggggtgg ggaaccctct
    14761 tttgacgagc tgtggaactg ccggaaaata ggcaaagctg caggaaccag tcggcaggta
    14821 acgttgggat ctgccgacaa caggactgtg atgacgtcct gtatgtatac gcttggcagc
    14881 gagcatcaat ttctgtactt gagtgcgcat ggtgcgcgtc acggctggtt caggctgcgc
    14941 tggctggttg acatcgacag gcttgcggta tgtgctgtcg attgggaggc gctactgccg
    15001 atgatgcgcc gctacggggg cctgcctgct ggcgggcagg cttgggcact cgccgctgcg
    15061 ctgttgggta cgccgatacc ggagccgatg cgtccggtat cggctacccg gcaggcgcac
    15121 aggctcgcgc tgagcgcgct ggccttcatg caggccagcg ttcccgcacc gtacccgatt
    15181 gcccacgggt cgggtacagg taggcttgct ccatcagagc cgctgtacag cagagctttg
    15241 gcggagcaag cggaggccgc acctccgaat ggcggtgctt cagtatgcga tacctgtggc
    15301 gaagcagcca tgcttgccac cagtggcgtt actagcatca cggaagatgc cagtaacgac
    15361 gatcatagcc cgatgagcac cgctaccagt tgtgccccca ttactccagc tgccgcctcc
    15421 agccaagtca tgaccagaaa cacggcggct gcccatcagc cggtcagtcg cacttacttg
    15481 ctttccttaa aagagccaag acacagacta tggtacctca tcagccgttt gtttccctct
    15541 acgggggatt cggccgtttt tccactgcct cgccagctgc attttttgta tatcccttta
    15601 cgtccctttc tttggctgaa acggcgattt tcaaagcact gactctcgat agaggatttt
    15661 gcaaaaatcc aataagcgac tttcaatgaa caatatatag atcgaaatgg cctagttcgt
    15721 ctatatattg cactttggag cgactgaaat cgaatttttc aaaatcctgg ataaggagtg
    15781 tgcattatgg ttcacctgcg attatatatg acaaagctgt atagcgtgaa cggcggtgcg
    15841 ttatttctca atattggatg tatgatcatg gtcagcctgc tggagggttt tggaatttat
    15901 atgcttgttc ctatgctggc ggccatcggc gtatttgtcg gtcattcggg aatgccattt
    15961 ctgtctggtg gattggaaca ttttttggcg ttcattccta aaagctggct gttgccgggg
    16021 atgttgatgg tttttatagt gctgcttaca gggcaggcta tgcttcagcg ttaccaatcc
    16081 atcctgaatt cgcggattca gcagcgtttt atgcgttccc ttcgaataga cgtgtacact
    16141 tcttttatga aggcgcagtg ggcattttat ttgcgtcagc gtaaatctga ttttagccat
    16201 gtgatgacga ctgagctggc gcgtgtcagt cagggaacga atttgcttct tcaactgact
    16261 acagccgtca tgtttacgat gatccagatt gcgttggctt tttggttatc cccctcttta
    16321 accggactag tatttctgag tggattgggg ctgtttgtcg tgttccgccg ctccattcga
    16381 aatgccaaac aattaggtga tcgtaccact gagctttcgc aggtttattt tgctggaatt
    16441 acggatcaca tgaacggcat gaaagatatt aaaagcaatc tgttggaagc ggcgaatatc
    16501 cattggtttc gttccctgac acaacgcatg gaggataata cgacccaatt tgtccggcaa
    16561 aatgcgacca cacagttttt tcatcgtaca gcggcagctg tttttgtcgc atgtgtcata
    16621 tttatatcgc tgcagtggct gcatgttact cctgaaaaac tgattgtgct gattcttata
    16681 ttttcccgct tatggccccg atttgctctt attcaagcga gtctggaata catcatgtct
    16741 atgatctccg cttttgaaag tgtcaccaag gtgcaacagg agtgcgaagc tttcacagat
    16801 ccttcattaa ttgtatctgc atctgtacgg caacccctgt cccttcgtca tgggatcgaa
    16861 tgcagccatc tggattatcg ctacgatggt gcagcagagt ctgcgctgcg taatattaac
    16921 ttgttcatac ccgctcgggg aatgacagcc attgtaggga aatcgggagc aggtaaaagt
    16981 acaatggtcg atgtcctgat gggtttttta cgtccaactg ggggacagat tacaatagac
    17041 gggcttgtgc tggacgacga attgttgctc cagtggcggc agtcgtttgg ctacgtgtca
    17101 caagacccct ttttatttca tgcgactgtc cgcgaaaatt tgatgctggc agataaggat
    17161 gctagtgagc agcagctatg ggaggcgtta cattttgccg ccgcagacaa ctttgtatcc
    17221 agattgcccg aagggctgga cacagtaatt ggagatcgcg ggattcgtct gtctggagga
    17281 gaacgtcaac ggctagtatt agcacgggct gtcttgcatc atccttcggt acttatacta
    17341 gatgaagcga caagtgcgct ggatggtgag catgaagccg caattcaggc agcactggaa
    17401 cggatgaaag gtcaaatgac gttgatcgtc attgcacacc gcctgtcaac catcagacat
    17461 gcggatcaaa ttgtcgtact ggatcaaggc gaggtcatac agcaggggaa ctaccaccaa
    17521 ctggaacaag aggagcgggg ggcgttcagt cagctactat cgtatcaaag cagtgtcacc
    17581 gccacccctt aaccagactt ttctgtacct cagcttaagt ttctttacgt ttggcagtgc
    17641 ttcttttctt tttggctgga gtcggagaga tgttctcgcc tgcaacagcc tgctgtgctg
    17701 atggggctgc tggtttacgc gcagggcgct ttttcgcagc agggccggga tcggtaacga
    17761 caggttgcac tgcctcgatg ctggcctgaa gggcggccat taaatctact acattggtct
    17821 gaggctgtgt tggggcgatt cgcacctctt caccagccac tttatgctga atgagatcca
    17881 gcagacgctc gcggtactga tccgtatact ttgctgcatc aaaaggtgta gatagctgct
    17941 cgatcagcat ttttgccatg gtcagctcct tctctttaac ctcctcctgc cccggtaagt
    18001 taggcacttg agcaatgggg cgaatttcat cggggtaaaa catcgtctcc accgccaaac
    18061 attcatccaa cacccgaata gccgccaggc tgcttttaga gcggatggag atttgggcaa
    18121 tcccgatttt tccggtatcc ttcatcgcat tcatgagcag cttatacgca ttggagccag
    18181 cttgatccgg ggacaaataa tacgttttct gaaagtaaat cggatcaatt tcctgcaaat
    18241 ccacaaaatc taaaataaca atatttttat ccgcttgtcc gctaacttgc tccagttcct
    18301 ccttgtcgaa catgacaaat tttccttttt catactcgta gccttttcca atttcctccc
    18361 actcgacctc cttatcacaa acgggacact ttcgtacata gctaagtggg cttccacact
    18421 ccttgtgaat ataacgcatg gaaatgtcct tatcctcagt cgcagaaaac attttaacgg
    18481 gcacatgaac cagcccaaaa ctgatcgcac ctttccagac cgtatgcata ccgcagtcct
    18541 ccttttctta aatccgcatt ttgcatcctt cgtttccggt caccccggga tatgagcata
    18601 taatttttca cttagtatgc ttcgtacaag tgattgtatg aggtgtaaag aaaagagcaa
    18661 gccaactaat ctgcattctg aggtgtgact acatcgcata acacaatgat atgaagttgt
    18721 taagtcacat tagttatatt aagataaggg ataatcaacg attttgacat tttataagaa
    18781 aggagtgttc atgtcatgaa gaaaagatca ttaaacttta tatcttttgg atatggatac
    18841 tctactgctg tttttttcta aaatcatttt tattggtgga gtctgcctaa aagtggttag
    18901 aagaaacggt agaaaaattt aaaaatgacg aggtcgatta aatgaaatat gaaaaaataa
    18961 ctagaaaaaa cccggcaggt atgccgaaac cagtagggaa ttacacacat ataactaaag
    19021 ttcccagaaa ttcagagcta ttcgtgactt cgggtcaagt tggagtagat cagaatggcc
    19081 aattcccaga aagctttaac ctacaaatca gcaatacttt taataacatt aaatcagttt
    19141 tggacgccga acaattaacc gctgacaata ttataaaagt aaatgtatgg gcaactgagc
    19201 agatagattg ggattacatg tattcccaat gggaaaagtt attcgggaat gattatcctg
    19261 caatgactat cggctacctt actgctctag gattgcctga aataaaaatt gaaattgaaa
    19321 tttgggcagc taaagcataa aaataatacg cacctcattt atgggatgga atcatagata
    19381 gccccggtct tcgtgagaag ctggggctgt tttatgttta aattcacgaa aaatgtacat
    19441 ccgtcgtagc aagcaaacgc actaaacaat taccgagcat cgcatagtga tgagctatcc
    19501 gcatctgcat ccttcgattc caacgccttg gctgtgagct aatcattttt atgcttcgta
    19561 caagtaattg tatgaggtat agatgaagac tgcgaattgc tttcgcgtgc gcatggttac
    19621 agcaagtttg gtgcatagta aggcatatcc gattcaaaag ggggtacaca atttatgtcc
    19681 ggaaaatcct atcctcagca aatcaggcat cgtgtgggtc aaagccaaat cgcctttcgg
    19741 ggcccagctg gaggcgaaca ggatgcattg ccgcccgagt ttgctctttc acatggaatc
    19801 cgtccgccat ttcccgtagc tgtggctcat gtggatttgg aggctgtagt ttcaacttca
    19861 ccttctcatg gcatcccttc attagacgtt gaacggatta tagatgaaga ctaggtgaac
    19921 tatatttctg aatgaatgca cacaacaaca atcaggaggg gaagaatagc atgaatgtgg
    19981 aacgagcaaa agctatttat gattcatccg aaaatattgc tgtacaattg gatggtaaac
    20041 cgatctggat tgagcatgta gaccaagcaa acggtatggc aacggtacag ataggtagca
    20101 gaccaggaaa tactcaaacc gtccgtgtgg atcgtctgga agaacaatag gagaggggca
    20161 ccaaacagat tttttcccat agtatggggt atagctttag aaagatcttg gacagctgta
    20221 ggctttcatc gtagaatgct gcttgaatgg tcccgctcca accctaaaag gctcgcaatt
    20281 gctcaatgag caattagcga accttatttg taataataaa tgcagtcgag ggggcagtta
    20341 aacgccggac aagttaattt gaaggtgcaa ctggctcctt tctatgacct ttatactgca
    20401 atggccttta aatgtggtga aaccatcagc ttagcctctg ttgccaattg aacgtcttcc
    20461 accgacaaac ccggagcaat ttcctttagc atcagccctt tacccggaat aacatcgatg
    20521 acagcttttt cggttactat ggtctttaca acatttacag cagtcagggg cagcttgcat
    20581 tgtttcagta ttttcggcgc cccatttttg ttcacatgct ccatggctac aatgactctc
    20641 ttggctccaa ccaccaaatc catggctccc cccatgcctg gaactttttt cccagggatc
    20701 atccagcttg caaggttgcc tttctcatcg acctccaggg cgcccaacac ggtgatatcc
    20761 acatgccctc cgcggatgat ggaaaatgaa agtgcactgt caaaaaagca tgctccttcc
    20821 atagttgtaa cgtagtttcc gcctgaatcg atacaatcga gcctttcttt tccctgagcc
    20881 gctttggggc ctacaccgag gattccattc tcagcctgca gcataatatg aatgttttcg
    20941 gggatatagt ccactaccat tgtaggcaat ccgacaccaa ggttgaccac ttcgccattt
    21001 ttgaattcct gggctattct tcgagcaatg aattctctgt tattcatgcg ttttcaccca
    21061 cctttacaat tgcgtcgaca aatattccgg gaacgttgac atgattgggg tcaatttctc
    21121 ccgtctttac gtattcgtct atctgagcaa ctacatactc tgccgctgta gccataacca
    21181 tattgaaatt acgtgaagag ccgttgatga caagattccc agcttcatca gccttatggg
    21241 ctctgattag cgccacatcc gctttgagcg ggagttcaag caaatattct ctttcatcaa
    21301 tttctatttt cttttttcct tcctctacaa cggtgcctac acctacaggt gttaaaacac
    21361 cgcccaaacc ggcccctcct gcgcgtattt tttcagcgag tgtgccttgc gggaaaagtt
    21421 ggacctctgc ttctttcgtc atcaggagcc ttcccgtttc tggattggag ccaatatagg
    21481 atgcaaaaat ccgctttact ctgccgcttt ttacaagctt ataaatagat aattccggtg
    21541 tgcctgtgtc attggaaata atcgtaagat tgctggcggg attggtgtcg acaagcgcac
    21601 gcaccaggtc ctccggaaag cctcctgcca gaaaacctcc gaccatcacc gtgtctccgt
    21661 ctttgatctt cttaactgct tcttcagcgg agattacttt gttattcatg gttccttctc
    21721 cttatatata tatttttagg aaagcaaact ttattggaga taatcgtaga ggactcttcc
    21781 atatggaagc gttaaatcag caataaaatg ttttccgcca atataagctt taaccggcaa
    21841 atctgccaca ggagcgttga catgggggat caggcttaat ctggcaggcc ctgaccaggc
    21901 gccttttaca gtaacgttct cgagattata cgctactaac tgagcgattt ttggggtacc
    21961 gtcaacgtca ggaattaatt tcaaattaac ttgcgttttt gcgatggctt tagccgtttc
    22021 cttttcatca agaatgttat atttgaaagg catggttccc gtggccacca ggacgttgtt
    22081 gtaatgcaat gtacccgtca gcgtctccgt ctcctcaacg atcaagcgag gcttcgccca
    22141 ttttttcgga aatccccaga tttcacgtcc tccaagaata gcaggcgcgt tatccaaata
    22201 catttgggca acaaaattac agggttctcc atgaaaagta cacggaatga caataccgct
    22261 ttcctcatag cttcctaacc cggatgaatc gggcatcttg atccattcat aggaaacggt
    22321 attgcttcca tccggctgaa gaggttccgg gaccgcttgt ctaatcgcag cgggatcgga
    22381 ttcataggta atgatcaaaa attcccggtt gatgaagcga caaggcgggc gcccataact
    22441 gccgctggcc gcaggcatgg attggagtga aagtacatct ttttgattca tagcgatctc
    22501 ccttcctttt aagaggtagt tctaaaagtc atcctgaact cgcactttaa atgagtgcat
    22561 tttcaactag catcgctatt cccattcccg ttccgatgca taacgaggcg atgccgtaac
    22621 gtgaagatct tcgcaccatt tcatgaacca gcgtaactaa taccctagca ccgcttgcac
    22681 cgacaggatg cccgatcgcg atcgcgccgc cattgacatt taccttctcc ggattgattc
    22741 caagctcttt cagtaccgct agtgcttgtg cggcgaacgc ttcattaatt tcaaaaagat
    22801 cgatgtcatc aatagacatt ccctgttgct ttagaagtga cgaaatggcc ttcaccggtc
    22861 ccattcccat atatgcaggg tcaacgccaa caagtgaata acccttgata tatgccaacg
    22921 gctttaacgc atgttcctta catttgtctt ccgacactac aagcatagcc gccgcgccat
    22981 cattgattcc tgaagcattt ccggcggtaa ctgttccgtt ttccttaaac gcaggtttta
    23041 attgagaaag tttttctttc gttgtatttc ctcttatgtg ttcgtcctcc gtgaaagaaa
    23101 tagtttcttt tttgtttttg atcatgactg gaacaatctg ctcttcaaaa agcttcttgt
    23161 ttttagcttc tacggccttt atctggcttt gataggcaaa ttcgtcctgt tcaagtcttg
    23221 aaattccata tttctcggca acattttctg cggtaattcc catatggtaa tggttgatcg
    23281 ggcacgtaag accgtcggcc accagggagt ctaccaactc accgttgcca agtttgtagc
    23341 cgtttcttgc atttcttagc aggtaagggg cattcgacat gctctccatg cctccggcca
    23401 agacgatgtt gccttgttca gccaatattg aattgtaagc taaagcaacg gcatggagtc
    23461 ctgaaccgca aaccgtgttt atcgttgttt cgggtacatc aatagggata ccggctttta
    23521 gtgccgcctg tctggcagga ttttggccat tgcccgcctg aagaacattt cccaaataaa
    23581 tttgatcaat caaagaaggc tctaatttac tttgctgaag gcatgctgtc atcacagttg
    23641 ctcccagttc aggagcgctt agaggcgcaa gggttttgtt aaaagagccg accgctgttc
    23701 tcaacgggct tactaaagct acttttttca ttaaaaactc acattccttt cgctgtgttc
    23761 aagacacaat acatccatga ttgcacttca attcgtaatt tccgctctta acctacgaaa
    23821 cgcagcgact gcaagataca tttacatgcg ggcatatcat ggtgcctaga cagtgagtat
    23881 gacggtccga tcgccttctt tcctggctgg aaattaaaac cagaattatc ataattctaa
    23941 tacagatttt gttcaatgtt caaatattta catatatcta tgtacagatg tttatagggc
    24001 catatactcc acaataatta ggccattcta acgttttctg ttaatttcta aatttttctg
    24061 aaaatcatga tcacaaattg aattttctgt taaaaatgaa agtttcaatc catatgt
//
