LOCUS       NZ_MNPQ01000040         7861 bp    DNA     linear   CON 11-AUG-2024
DEFINITION  Streptomyces albidoflavus strain OsiLf-2 Scaffold36_1, whole genome
            shotgun sequence.
ACCESSION   NZ_MNPQ01000040
VERSION     NZ_MNPQ01000040.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces albidoflavus
  ORGANISM  Streptomyces albidoflavus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
REFERENCE   1  (bases 1 to 7861)
  AUTHORS   Zhu,Y., Zeng,X., Zeng,J. and Liu,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2016) College of Biology, Hunan University, 1
            Denggao Road, Changsha, Hunan 410082, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. FEBRUARY-2016
            Genome Coverage                   :: 140.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001865795.1-RS_2024_08_11
            Annotation Date                   :: 08/11/2024 02:37:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,098
            CDSs (total)                      :: 6,022
            Genes (coding)                    :: 5,927
            CDSs (with protein)               :: 5,927
            Genes (RNA)                       :: 76
            rRNAs                             :: 3, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 44 of 95
            Pseudo Genes (incomplete)         :: 58 of 95
            Pseudo Genes (internal stop)      :: 9 of 95
            Pseudo Genes (multiple problems)  :: 15 of 95
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:10:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 7861
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MNPQ01000040.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     protocluster    1..7861
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[6259:7846](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(6260..7846)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     gene            complement(<1..6263)
                     /locus_tag="BGV78_RS29860"
     CDS             complement(<1..6263)
                     /NRPS_PKS="Domain: PKS_DH2 (11-219). E-value: 2.5e-16.
                     Score: 51.8. Matches aSDomain:
                     nrpspksdomains_BGV78_RS29860_PKS_DH2.1"
                     /NRPS_PKS="Domain: PKS_KR (504-680). E-value: 3.1e-49.
                     Score: 159.3. Matches aSDomain:
                     nrpspksdomains_BGV78_RS29860_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (745-826). E-value: 7.6e-13.
                     Score: 40.6. Matches aSDomain:
                     nrpspksdomains_BGV78_RS29860_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (862-1277). E-value:
                     7.4e-143. Score: 468.4. Matches aSDomain:
                     nrpspksdomains_BGV78_RS29860_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_PP (1725-1805). E-value: 9.5e-12.
                     Score: 37.1. Matches aSDomain:
                     nrpspksdomains_BGV78_RS29860_PKS_PP.2"
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (1849-2087).
                     E-value: 5.3e-80. Score: 261.3. Matches aSDomain:
                     nrpspksdomains_BGV78_RS29860_PKS_KS.2"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) tra_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508347.1"
                     /locus_tag="BGV78_RS29860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_071339556.1"
                     /sec_met_domain="adh_short (E-value: 1.4e-45, bitscore:
                     142.6, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 6.8e-146, bitscore:
                     473.5, seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.7e-12, bitscore:
                     32.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 4.9e-71, bitscore:
                     226.3, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 1.8e-81, bitscore: 261.3,
                     seeds: 2284, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPRAETYEKAFAGREPLIAQHRAEGAGLLPAAVQIEMALAGIAR
                     RRPFVPLELTDVAFLRPLALTPEETVPVRLDVTHEDAPGEGARFELSAVLAGERKQLST
                     GTGRLLRDGETAPRHAAHPAADGRPLTPQELYEGWSRAGLDYGPDFRTVRELTVGDGTA
                     RARLRTDSEPLPWHAHPLLVDGVLQVVSCALQELGADTPPVPMLPIGIARVAVLADLSA
                     RATGVTVLVRRTGVEGAYATGDAVVLGPSGETAAEFTGVRMRRTTGPGVVRTAPAATRH
                     PLSRIEWRPAAAPPAPRPDTTGTWVVLRHGDDDRLADETGRLLRTGGARVVDAYLGAPA
                     GREGSGQDHHVLADTGEAAFRGLWEAVGEEVAGVVHLGNSGPVRAEAGELATGPYGCAA
                     ALKTLGERQRRARFLVVTHAAQPVADGDRPVPARAALWGLMRTAAVEYPGLRPRLLDLD
                     EESEPALPAELGDGPPETGYRHGVRHEPVRVSTRPGATGTPPVRRGGHYLILGGHGGLG
                     LALAERLAHEGAAVVALASRSGGASTGHPPSQQIEGTACSLRSYAVDVTAPGALTDLVG
                     RIRADVGELHGVVHAAGTLKDGLLRSATAEDLAAVMRPKVDGVRELAAAVAGSELDFAV
                     LFASVSGAFGNLGQGGYAAANAYLDGFAHAHGAPWTSVDWGLWGETGMGTAVAAQLRRR
                     GVRPLGTTEALDALLAVLGDPPRQVVIAHPDASDTLADEEPPPAPVRAPAGKAPTPHAQ
                     RARVEDELARFLTDRLGLASFDRATPLADHGMSSIMSVELAEELSRRWDVHLPATLFLE
                     YGGLTELAEALTERYGVAAALPAPPAPAPPAPAPQPPVATTAARTTRPEDIAVVAVSAD
                     LPGATSLEGFWHLLRSGRHAFTEVPAERWDVAAHFEPRGPQMTGTYCRSGAFLSDIDRF
                     DPAFFSISVREAEEMDAQQKLLLEHAWSVRDESGLAGHRDIGVFVGATYTHHRDAHGLE
                     EVGPHTALGSMNAVLANRISYALDLTGPSQTVDTLCSSGLVAVQQAVAALRAGQCGAAL
                     VAACHVGLTPWYYRSLSQLGALSESRPRPFDDRADGFLPGEGAVAVMLKPLAAAERDGD
                     TVWGVIRGAAVNHGGRGSALPVPRSEAQSAVVRAALADAELDASDITLIETHGTATRLG
                     DPIEIAALTEVFGAGPERREPCLLGSAKANIGHLEPASGLAGLVKILLCLRHREVPPLA
                     GFERPGSHLDLDAGPFTVPTAPLPWPGGDRPRRAGLSAFGMGGTNAHVVVEERVPGESV
                     PEGPPDVLGEHLLVLSGHTPEALVRRARDLLRLLSEEDAPDAAALCRSAAVGRDHQRHR
                     AAVLGSGPEQLRAGLDRIARHHGDAHGTVLRDGRVVATDLGPATGTADTAPYARLATYT
                     TVGADRLRAQLALPDDRLSTALACFHVSGGSVDWRQVHAGTRARRIVLPPYPFRTPSGD
                     QPAASRPDPDDSVRRLTRAHRVFGEPTVPAALPLALALDHAEVLEHVTFTARGTGDGPL
                     TGDLDDPGRTGPAAFRHGERVIARLTTANRTQDPVPAAPDLAQLRAGLDRGLEPEGLYA
                     WFAAQGMEIEAPLRSLAGLRYGATRVLARLDTPAEGGPERAAVALDAALQSMAVLTLAD
                     PAVPRGTYLPVSVARVVRWDDPARTAYVLLDAEHTGADPVRRGEATLLARDGRVLARLS
                     GIEYRPVAGPGAPEPEATAPRPRAEPSATPPGAEHLAAAEAAVLAAVRGVFHDPGITAT
                     TPLSGAGLDSLLATAVAADLESAHGLRVSLADVLDAPDCRTLAQYLAERAAEGTFPPAQ
                     EAGPAAASRPEPPWAERPAAVPAQADDEVRDGDLAIIGFAFALPGAQDEAALWSLLADG
                     GTAVRPAPAHRWGAYADRRHTDVGGFLDNAEEFDARFFDFFPKQAEVLDPQARWLLRTT
                     WEALESAGLPPRQLAPATGVFVGASYQHYREYNIAPELDAHSGLGNHNAFLANRLSHFL
                     DLRGPSMTVDTLCSSSLVALHQAVRSIRSGECEQAVVAGVRVGMSPLHYVAMRELRALS
                     PSGVVRAFDAGADGFVPGEGVVSVVVKSLGAALRDG"
     source          1..7861
                     /collection_date="2015-11"
                     /db_xref="taxon:1886"
                     /geo_loc_name="China:Changsha, Hunan"
                     /host="rice"
                     /isolation_source="rice"
                     /lat_lon="28.4196 N 114.02870000 E"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces albidoflavus"
                     /strain="OsiLf-2"
                     /submitter_seqid="Scaffold36_1"
     region          1..7861
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..7861
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     aSDomain        complement(3..716)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS29860_PKS_KS.2"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="5.30E-80"
                     /label="BGV78_RS29860_PKS_KS.2"
                     /locus_tag="BGV78_RS29860"
                     /protein_end="2087"
                     /protein_start="1849"
                     /score="261.3"
                     /specificity="transATor: (unknown)"
                     /tool="antismash"
                     /translation="AIIGFAFALPGAQDEAALWSLLADGGTAVRPAPAHRWGAYADRRH
                     TDVGGFLDNAEEFDARFFDFFPKQAEVLDPQARWLLRTTWEALESAGLPPRQLAPATGV
                     FVGASYQHYREYNIAPELDAHSGLGNHNAFLANRLSHFLDLRGPSMTVDTLCSSSLVAL
                     HQAVRSIRSGECEQAVVAGVRVGMSPLHYVAMRELRALSPSGVVRAFDAGADGFVPGEG
                     VVSVVVKSLGAALRDG"
     CDS_motif       complement(51..89)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS29860_0008"
                     /evalue="3.20E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="BGV78_RS29860"
                     /protein_end="2071"
                     /protein_start="2058"
                     /score="10.8"
                     /tool="antismash"
                     /translation="FDAGADGFVPGEG"
     CDS_motif       complement(231..278)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS29860_0007"
                     /evalue="2.00E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="BGV78_RS29860"
                     /protein_end="2011"
                     /protein_start="1995"
                     /score="19.7"
                     /tool="antismash"
                     /translation="GPSMTVDTLCSSSLVA"
     aSDomain        complement(849..1088)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS29860_PKS_PP.2"
                     /evalue="9.50E-12"
                     /label="BGV78_RS29860_PKS_PP.2"
                     /locus_tag="BGV78_RS29860"
                     /protein_end="1805"
                     /protein_start="1725"
                     /score="37.1"
                     /tool="antismash"
                     /translation="TPPGAEHLAAAEAAVLAAVRGVFHDPGITATTPLSGAGLDSLLAT
                     AVAADLESAHGLRVSLADVLDAPDCRTLAQYLAER"
     aSModule        complement(849..3677)
                     /complete
                     /domains="nrpspksdomains_BGV78_RS29860_PKS_KS.1"
                     /domains="nrpspksdomains_BGV78_RS29860_PKS_PP.2"
                     /locus_tags="BGV78_RS29860"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(2433..3677)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS29860_PKS_KS.1"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="7.40E-143"
                     /label="BGV78_RS29860_PKS_KS.1"
                     /locus_tag="BGV78_RS29860"
                     /protein_end="1277"
                     /protein_start="862"
                     /score="468.4"
                     /specificity="transATor: (unknown)"
                     /tool="antismash"
                     /translation="IAVVAVSADLPGATSLEGFWHLLRSGRHAFTEVPAERWDVAAHFE
                     PRGPQMTGTYCRSGAFLSDIDRFDPAFFSISVREAEEMDAQQKLLLEHAWSVRDESGLA
                     GHRDIGVFVGATYTHHRDAHGLEEVGPHTALGSMNAVLANRISYALDLTGPSQTVDTLC
                     SSGLVAVQQAVAALRAGQCGAALVAACHVGLTPWYYRSLSQLGALSESRPRPFDDRADG
                     FLPGEGAVAVMLKPLAAAERDGDTVWGVIRGAAVNHGGRGSALPVPRSEAQSAVVRAAL
                     ADAELDASDITLIETHGTATRLGDPIEIAALTEVFGAGPERREPCLLGSAKANIGHLEP
                     ASGLAGLVKILLCLRHREVPPLAGFERPGSHLDLDAGPFTVPTAPLPWPGGDRPRRAGL
                     SAFGMGGTNAHVVVEE"
     CDS_motif       complement(2754..2798)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS29860_0006"
                     /evalue="7.00E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="BGV78_RS29860"
                     /protein_end="1170"
                     /protein_start="1155"
                     /score="9.3"
                     /tool="antismash"
                     /translation="IETHGTATRLGDPIE"
     CDS_motif       complement(2994..3032)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS29860_0005"
                     /evalue="6.60E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="BGV78_RS29860"
                     /protein_end="1090"
                     /protein_start="1077"
                     /score="9.9"
                     /tool="antismash"
                     /translation="FDDRADGFLPGEG"
     CDS_motif       complement(3171..3218)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS29860_0004"
                     /evalue="8.40E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="BGV78_RS29860"
                     /protein_end="1031"
                     /protein_start="1015"
                     /score="14.9"
                     /tool="antismash"
                     /translation="GPSQTVDTLCSSGLVA"
     aSDomain        complement(3786..4028)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS29860_PKS_PP.1"
                     /evalue="7.60E-13"
                     /label="BGV78_RS29860_PKS_PP.1"
                     /locus_tag="BGV78_RS29860"
                     /protein_end="826"
                     /protein_start="745"
                     /score="40.6"
                     /tool="antismash"
                     /translation="KAPTPHAQRARVEDELARFLTDRLGLASFDRATPLADHGMSSIMS
                     VELAEELSRRWDVHLPATLFLEYGGLTELAEALTER"
     aSModule        complement(3786..6230)
                     /domains="nrpspksdomains_BGV78_RS29860_PKS_DH2.1"
                     /domains="nrpspksdomains_BGV78_RS29860_PKS_KR.1"
                     /domains="nrpspksdomains_BGV78_RS29860_PKS_PP.1"
                     /incomplete
                     /locus_tags="BGV78_RS29860"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(4224..4751)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS29860_PKS_KR.1"
                     /evalue="3.10E-49"
                     /label="BGV78_RS29860_PKS_KR.1"
                     /locus_tag="BGV78_RS29860"
                     /protein_end="680"
                     /protein_start="504"
                     /score="159.3"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GHYLILGGHGGLGLALAERLAHEGAAVVALASRSGGASTGHPPSQ
                     QIEGTACSLRSYAVDVTAPGALTDLVGRIRADVGELHGVVHAAGTLKDGLLRSATAEDL
                     AAVMRPKVDGVRELAAAVAGSELDFAVLFASVSGAFGNLGQGGYAAANAYLDGFAHAHG
                     APWTSVDWGLWGE"
     CDS_motif       complement(4269..4373)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS29860_0003"
                     /evalue="2.50E-15"
                     /label="PKSI-KR_m4"
                     /locus_tag="BGV78_RS29860"
                     /protein_end="665"
                     /protein_start="630"
                     /score="49.0"
                     /tool="antismash"
                     /translation="LDFAVLFASVSGAFGNLGQGGYAAANAYLDGFAHA"
     CDS_motif       complement(4650..4745)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS29860_0002"
                     /evalue="5.60E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="BGV78_RS29860"
                     /protein_end="538"
                     /protein_start="506"
                     /score="25.4"
                     /tool="antismash"
                     /translation="YLILGGHGGLGLALAERLAHEGAAVVALASRS"
     aSDomain        complement(5607..6230)
                     /aSDomain="PKS_DH2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS29860_PKS_DH2.1"
                     /evalue="2.50E-16"
                     /label="BGV78_RS29860_PKS_DH2.1"
                     /locus_tag="BGV78_RS29860"
                     /protein_end="219"
                     /protein_start="11"
                     /score="51.8"
                     /tool="antismash"
                     /translation="FAGREPLIAQHRAEGAGLLPAAVQIEMALAGIARRRPFVPLELTD
                     VAFLRPLALTPEETVPVRLDVTHEDAPGEGARFELSAVLAGERKQLSTGTGRLLRDGET
                     APRHAAHPAADGRPLTPQELYEGWSRAGLDYGPDFRTVRELTVGDGTARARLRTDSEPL
                     PWHAHPLLVDGVLQVVSCALQELGADTPPVPMLPIGIARVAVLAD"
     CDS_motif       complement(6138..6209)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS29860_0001"
                     /evalue="5.40E-05"
                     /label="PKSI-DH_m2"
                     /locus_tag="BGV78_RS29860"
                     /protein_end="42"
                     /protein_start="18"
                     /score="15.8"
                     /tool="antismash"
                     /translation="IAQHRAEGAGLLPAAVQIEMALAG"
     gene            complement(6260..7846)
                     /locus_tag="BGV78_RS29865"
     CDS             complement(6260..7846)
                     /NRPS_PKS="Domain: PKS_AT (161-450). E-value: 1.6e-87.
                     Score: 285.6. Matches aSDomain:
                     nrpspksdomains_BGV78_RS29865_PKS_AT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012901.4"
                     /locus_tag="BGV78_RS29865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I polyketide synthase"
                     /protein_id="WP_079177552.1"
                     /sec_met_domain="mod_KS (E-value: 1.7e-18, bitscore: 53.7,
                     seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 5.2e-89, bitscore: 285.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHGVVPGSLHVRRPNDHIRFEDSPFFLVDRAWVWGREEGPRRGA
                     VSAFGMGGVNAHVIVEEPPRVERGAVVVQDSHLVRVTGADARAVRELAAAYADHLTAVP
                     DTDPGDFARTVNTGRAAQRWTTAVHGTGRAELAARLTEIADGTTQPVRSAGRQVTAFLY
                     TGQGSQYAGMARRLLTTEPHFRDALHECADLLAPHLDVPLLDLLHGDARHLLDETRYAQ
                     PAVVSVEVALTRLLAEAGVRPDTVAGHSLGELTAAWAAGVLGLPDLLRLTAVRGALMQG
                     RSTDGTMAVVHTGTATLTEALRNHPGVEIAAYNGRTHTVTGPEQDIARFCEESPYRTQR
                     LTVSHAFHSAAMEPAVRPFAEAVAATALRAPELPFADTLTGDWHTAATATDPQRWADAI
                     RRPVRFAQALTTLAGEGPHVVWEIGPHPQLLPMARTVLAEPHPVWVPTLHRERNDQVQL
                     HAALAAHHRATGAELDWAALHAGKNQRTTTAPTYPFARQELTAPPARRATANAVSHPLF
                     DHPYEHRSEAE"
     CDS_motif       complement(6452..6472)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS29865_0004"
                     /evalue="9.90E+01"
                     /label="PKSI-AT-M_m6"
                     /locus_tag="BGV78_RS29865"
                     /protein_end="465"
                     /protein_start="458"
                     /score="-4.1"
                     /tool="antismash"
                     /translation="HAALAAH"
     aSDomain        complement(6497..7363)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS29865_PKS_AT.1"
                     /evalue="1.60E-87"
                     /label="BGV78_RS29865_PKS_AT.1"
                     /locus_tag="BGV78_RS29865"
                     /protein_end="450"
                     /protein_start="161"
                     /score="285.6"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LYTGQGSQYAGMARRLLTTEPHFRDALHECADLLAPHLDVPLLDL
                     LHGDARHLLDETRYAQPAVVSVEVALTRLLAEAGVRPDTVAGHSLGELTAAWAAGVLGL
                     PDLLRLTAVRGALMQGRSTDGTMAVVHTGTATLTEALRNHPGVEIAAYNGRTHTVTGPE
                     QDIARFCEESPYRTQRLTVSHAFHSAAMEPAVRPFAEAVAATALRAPELPFADTLTGDW
                     HTAATATDPQRWADAIRRPVRFAQALTTLAGEGPHVVWEIGPHPQLLPMARTVLAEPHP
                     VWVPTLHR"
     CDS_motif       complement(6800..6826)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS29865_0003"
                     /evalue="8.80E-03"
                     /label="PKSI-AT-M_m6"
                     /locus_tag="BGV78_RS29865"
                     /protein_end="349"
                     /protein_start="340"
                     /score="9.2"
                     /tool="antismash"
                     /translation="LTVSHAFHS"
     CDS_motif       complement(7007..7129)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS29865_0002"
                     /evalue="1.20E-18"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="BGV78_RS29865"
                     /protein_end="280"
                     /protein_start="239"
                     /score="59.3"
                     /tool="antismash"
                     /translation="GVRPDTVAGHSLGELTAAWAAGVLGLPDLLRLTAVRGALMQ"
     CDS_motif       complement(7313..7366)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS29865_0001"
                     /evalue="5.50E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="BGV78_RS29865"
                     /protein_end="178"
                     /protein_start="160"
                     /score="18.7"
                     /tool="antismash"
                     /translation="FLYTGQGSQYAGMARRLL"
ORIGIN
        1 tcaccatcac gcaacgccgc acccaacgac ttcaccacca ccgacaccac cccctccccc
       61 ggcacaaacc catccgcacc cgcatcgaac gcccgcacca cacccgaggg cgacagggcc
      121 cgcagctcac gcatggcgac gtagtgcagc gggctcatcc cgacgcggac accggcgacg
      181 acggcctgtt cgcactcccc gctccggatg gaccgcaccg cctggtgcaa cgccaccagc
      241 gacgacgagc acaacgtgtc caccgtcatg ctcggacccc gcagatccag gaagtgactg
      301 aggcggttgg cgaggaaggc gttgtggttg cccagtccgc tgtgggcgtc gagttcgggg
      361 gcgatgttgt actcgcggta gtgctggtag ctggcgccca cgaacacgcc tgtcgcgggg
      421 gccagttgcc ggggcgggag gccggccgac tccagcgcct cccaggtggt gcgcagcagc
      481 cagcgggcct gcgggtcgag cacctcggcc tgcttgggga agaagtcgaa gaagcgggcg
      541 tcgaactcct cggcgttgtc gaggaatccg ccgacgtcgg tgtggcgccg gtccgcgtag
      601 gcgccccacc ggtgggccgg tgccggccgg acggcggtgc ccccgtcggc cagcagtgac
      661 cagagcgccg cctcgtcctg ggcgccgggc agggcgaagg cgaatccgat gatcgccagg
      721 tcgccgtcac gcacctcgtc gtcggcctgg gcgggcaccg cggcgggacg ctccgcccat
      781 ggcggctccg gccggctcgc ggcggcgggg ccggcttcct gcgccggggg gaaggtcccc
      841 tcggcggcgc gttcggcgag gtactgggcg agggtgcggc agtccggcgc gtccagcacg
      901 tccgccaggc tcacccggag gccgtgggcg ctctccaggt cggccgcgac agcggtcgcc
      961 agcagggagt cgaggccggc gccggagagc ggggtggtgg cggtgatgcc cgggtcgtgg
     1021 aagacgcccc gcacggctgc gaggacggcg gcctcggcgg cggccaggtg ttccgccccc
     1081 ggcggcgtgg cggacggctc ggcccgcggg cgcggggcgg tcgcctcggg ctccggtgcc
     1141 cccgggccgg cgaccggccg gtactcgatg ccgctgagcc gggcgaggac ccggccgtcg
     1201 cgggcgagca gggtcgcctc gccccggcgg acggggtcgg cgccggtgtg ttcggcgtcg
     1261 agcaggacgt aggcggtacg ggccgggtcg tcccagcgga ccacccgggc cacggagacc
     1321 ggcaggtacg tcccccgggg gacggcgggg tcggcgagag tgaggacggc catgctctgc
     1381 agagcggcgt ccagggcgac cgcggcgcgc tccggtccgc cctcggccgg ggtgtccagc
     1441 cgggcgagca cgcgcgtggc accgtagcgg aggccggcga gggagcgcag gggtgcctcg
     1501 atctccatgc cctgggcggc gaaccaggcg tacaggccct ccggttcgag gccgcggtcg
     1561 agtccggcgc gcagctgggc gaggtcgggt gcggcgggta cggggtcctg ggtgcggttg
     1621 gccgtcgtca ggcgggcgat gacgcgctcg ccgtggcgga aggcggccgg gccggtgcgg
     1681 ccggggtcgt cgaggtcgcc ggtgagcggg ccgtcgccgg tcccccgggc ggtgaaggtg
     1741 acgtgttcca ggacttcggc gtggtcgagg gcgagcgcca ggggcagggc ggcggggacg
     1801 gtcggctcgc cgaagacgcg gtgggcgcgg gtcaggcgcc ggacgctgtc gtccgggtcc
     1861 gggcgggaag cggccggctg gtcgccggag ggggtccgga aggggtaggg cggcagcacg
     1921 atgcggcggg cccgcgtacc ggcgtggacc tggcgccagt cgacgctgcc gccgctcacg
     1981 tggaagcagg ccagtgccgt gctcaggcgg tcgtcgggca gggccagttg ggcccggagc
     2041 cggtcggcgc cgacggtggt gtacgtggcg aggcgcgcgt agggggcggt gtcggccgtg
     2101 ccggtggcgg ggccgaggtc ggtggcgacc acgcgcccgt cgcgcaggac cgttccgtgg
     2161 gcgtcgccgt ggtggcgggc gatccggtcg agcccggccc tcagttgctc cgggccggag
     2221 ccgaggacgg cggcgcggtg gcgctggtgg tcgcggccga ccgcggccga gcggcacagt
     2281 gccgccgcgt cgggggcgtc ctcctcgctg agcagccgaa gcaggtcgcg ggcacgccgg
     2341 accagggcct cgggggtgtg tccggagagg accaggaggt gttcgcccag cacgtcgggc
     2401 ggcccctcgg ggacggactc cccgggaacg cgttcctcga cgacgacgtg ggcgttggtg
     2461 ccgcccatgc cgaaggcgct gaggcccgcc cggcgcgggc ggtcgccgcc cggccacggc
     2521 agcggtgccg tcgggacggt gaacggcccg gcgtcgaggt cgagatggct gccgggccgc
     2581 tcgaacccgg cgagcggcgg cacctcgcgg tggcgcaggc agagcaggat cttgaccagg
     2641 ccggccaggc cgctggcggg ctccaggtgg ccgatgttgg ccttggcgga gccgaggagg
     2701 cagggctccc ggcgctccgg accggcgccg aacacctcgg tgagggcggc gatctcgatg
     2761 gggtcgccca gccgggtcgc cgtgccgtgg gtctcgatca gggtgatgtc ggaggcgtcc
     2821 agctccgcgt cggccagggc ggcgcggacg acggcgctct gggcctcgct acggggcacc
     2881 ggcagggcgc tgccgcggcc tccgtggttg acggcggcgc cgcggatcac cccccagacg
     2941 gtgtcgccgt cccgttcggc ggcggcgagc ggcttcagca tgacggcgac cgcgccttcg
     3001 ccgggcagga agccgtcggc gcggtcgtcg aaggggcgcg gccgggactc ggacagggcg
     3061 ccgagctggc tgaggctgcg gtagtaccag ggggtgaggc cgacgtggca ggcggccacg
     3121 agggcggcgc cgcactggcc ggcgcgcagg gccgcgacgg cctgctggac ggcgaccagg
     3181 ccggacgagc agagcgtgtc gacggtctgg gagggcccgg tgaggtccag ggcgtaggag
     3241 atccggttgg cgagcacggc gttcatcgag ccgagcgcgg tgtgcggccc gacctcctcc
     3301 agcccgtggg cgtcgcggtg gtgggtgtag gtggcgccga cgaagacgcc gatgtcccgg
     3361 tgtccggcga ggccgctctc gtcgcggacg gaccaggcgt gttcgaggag cagtttctgc
     3421 tgggcgtcca tctcctcggc ctcgcggacg gagatggaga agaacgcggg gtcgaagcgg
     3481 tcgatgtcgc tgaggaaggc tccgctgcgg cagtacgtgc cggtcatctg cggaccgcgc
     3541 ggctcgaagt gggcggcgac gtcccagcgt tcggcgggca cctcggtgaa ggcgtgccgt
     3601 ccggagcgca ggaggtgcca gaagccctcc aggctggtgg cgccgggcag gtcggcggag
     3661 accgcgacga cggcgatgtc ctcgggccgg gtggtgcggg cggccgtggt cgccaccggg
     3721 ggctgtgggg cgggggcggg gggcgcgggc gccgggggcg cggggagggc ggcggcgact
     3781 ccgtagcgtt cggtcagggc ctcggccagt tcggtgaggc cgccgtactc caggaagagg
     3841 gtggcgggga ggtggacgtc ccatctgcgg gacagttcct cggccagttc gacgctcatg
     3901 atggagctca tgccgtggtc cgccagtggg gtggcgcggt cgaaggaggc caggccgagg
     3961 cggtcggtga ggaacctggc caactcgtcc tctacacggg cgcgttgcgc gtgcggggtg
     4021 ggagcctttc cggcgggcgc ccgtaccggt gcgggcggag gctcctcgtc ggcgagggtg
     4081 tcggaggcgt ccgggtgggc gatgacgacc tggcgcggcg gatcgcccag caccgcgagg
     4141 agggcgtcga gggcctcggt ggtgcccagg ggccgcacgc cgcgtcgccg cagttgcgcg
     4201 gcgacggccg tgcccatgcc ggtctcgccc cacagccccc agtcgacgct cgtccacggt
     4261 gcgccgtggg cgtgggcgaa gccgtcgagg taggcgttgg ccgccgcgta gccgccctgg
     4321 ccgaggttgc cgaaggcacc ggagacggag gcgaacagga ccgcgaagtc cagctccgag
     4381 ccggcgacgg cggcggcgag ttcgcggacg ccgtccacct tcggccgcat caccgcggcg
     4441 aggtcctcgg cggtggccga gcggagcagc ccgtccttga gggtcccggc cgcgtgcacg
     4501 actccgtgca gctcaccgac gtccgcgcgg atgcgcccga ccaggtcggt gagggctccg
     4561 ggggcggtga cgtcgacggc gtacgagcgg agggagcagg cggttccctc gatctgctgc
     4621 gacggggggt ggccggtgct cgcgccgccc gagcggctgg cgagggcgac gacggccgcg
     4681 ccctcgtggg cgagccgctc ggcgagggcg aggcccaggc cgccgtggcc gccgaggatc
     4741 aggtagtggc cgcctcggcg cacgggcggg gtgccggtgg cgcccgggcg ggtggaaacc
     4801 cgcaccggtt cgtggcggac gccgtggcgg tagccggtct ccggggggcc gtcgccgagt
     4861 tcggccggga gcgccggctc ggactcctcg tcgaggtcga ggaggcgggg ccgcaggccg
     4921 gggtactcga cggccgcggt gcgcatcagg ccccagagag cggcgcgggc ggggaccggc
     4981 cggtctccgt cggccacggg ctgggccgcg tgggtcacga cgaggaaccg ggcgcggcgc
     5041 tgtcgctcgc cgagggtctt cagggcggcg gcgcagccgt acgggccggt ggccagttcg
     5101 ccggcctccg cgcggaccgg accgctgttg cccaggtgga cgacgccggc cacctcctcg
     5161 ccgaccgctt cccagaggcc gcggaacgcc gcctcgccgg tgtcggcgag gacatggtgg
     5221 tcctggcctg acccttcccg gcctgccggg gctccgaggt acgcgtcgac cacgcgggcg
     5281 ccgccggtcc gcagcagccg gccggtctcg tccgcgaggc ggtcgtcgtc gccgtggcgc
     5341 aggacgaccc aggtgccggt cgtgtcgggc cggggtgccg ggggtgcggc ggcggggcgc
     5401 cactcgatgc gggagagcgg gtggcgggtg gcggcggggg ccgtccggac cacgcccggc
     5461 ccggtggtcc ggcgcatccg tacgccggtg aactcggcgg cggtctcccc ggacgggccg
     5521 aggacgacag cgtcgcccgt cgcgtacgcg ccctcgacgc cggtgcggcg taccagcacg
     5581 gtcaccccgg tggcgcgggc cgacaggtcg gcgaggaccg cgacgcgggc gatgccgatg
     5641 ggcagcatcg gcacgggtgg ggtgtcggcg ccgagttcct ggagcgcgca gctgaccacc
     5701 tggaggacgc cgtcgaccag cagggggtga gcgtgccagg gcaggggctc gctgtcggtg
     5761 cgcagccggg cgcgggcggt gccgtcgccc acggtgagtt cccggacggt ccggaagtcg
     5821 gggccgtagt cgaggcccgc gcgggaccag ccctcgtaca gctcctgcgg tgtgaggggg
     5881 cgtccgtcgg cggccggatg ggcggcgtgg cggggcgcgg tctccccgtc gcgcagcagg
     5941 cggccggttc cggtggagag ctgcttgcgt tcgccggcca ggacggcgct cagctcgaag
     6001 cgggcgcctt cccccggggc gtcctcgtgg gtgacgtcca ggcggacggg cacggtctct
     6061 tcaggggtga gggcgagggg gcgcaggaag gcgacatcgg tgagttccag cgggacgaac
     6121 ggccggcgac gggcgatccc cgccagcgcc atctcgatct gcacggcggc cggcagcagc
     6181 ccggcgccct cggcgcggtg ctgggcgatg aggggttcgc gccccgcgaa ggccttctcg
     6241 taggtctcgg ctcgtggcgt cactctgctt cactccggtg ctcgtaaggg tggtcgaaca
     6301 gcgggtggct gacggcgttc gccgtggcgc ggcgagcggg gggtgcggtc agctcctgtc
     6361 gggcgaaggg gtacgtgggg gcggtggtgg tgcgctggtt cttgccggcg tgcagagcgg
     6421 cccagtccag ctccgcgccg gtggcccggt ggtgggcggc cagggcggcg tgcagctgga
     6481 cctggtcgtt gcgctcccgg tgcagcgtgg gcacccagac cgggtggggc tcggcgagga
     6541 cggtgcgggc catcggcagg agctgggggt gcgggccgat ctcccagacg acgtgcgggc
     6601 cttcgccggc gagcgtggtc agcgcctggg cgaagcggac ggggcgccgg atggcgtccg
     6661 cccaccgctg tgggtcggtg gcggtcgccg cggtgtgcca gtcaccggtg agtgtgtcgg
     6721 cgaaggggag ttccggcgcg cgcagcgcgg tggcggcgac ggcctcggcg aagggccgca
     6781 cggccggttc catggcggcg gagtggaagg cgtggctgac ggtaagccgc tgggtgcggt
     6841 acgggctctc ctcgcagaag cgggcgatgt cctgctccgg cccggtgacc gtgtgggtgc
     6901 gcccgttgta cgcggcgatc tcgacacccg ggtggttccg cagcgcctcg gtcagcgtgg
     6961 cggtgccggt gtggacgacg gccatggtcc cgtccgtgga ccggccctgc atgagggcgc
     7021 cgcgtactgc ggtgagccgc agcaggtcgg gcaggccgag gacgccggcg gcccaggcgg
     7081 cggtgagttc gccgaggctg tgcccggcga cggtgtcggg gcgtaccccc gcctcggcca
     7141 gcaggcgggt cagggcgacc tcgacgctga cgacggcggg ctgggcgtac cgggtctcgt
     7201 cgagcaggtg ccgggcgtcg ccgtggagca ggtcgagcag gggcacgtcc agatgcgggg
     7261 cgagcaggtc ggcgcactcg tgcagggcgt cgcggaagtg gggttcggtg gtgagcagac
     7321 gccgggccat gccggcgtac tgggagccct gcccggtgta gaggaaggcg gtgacctgac
     7381 gtccggcgga ccggacgggc tgcgtggtgc cgtcggcgat ctcggtgagg cgggcggcca
     7441 gttcggcgcg gccggtgccg tggacggccg tggtccagcg ctgggctgcg cgcccggtgt
     7501 tcacggtgcg ggcgaagtct cctgggtcgg tgtccggaac ggcggtgagg tggtcggcgt
     7561 aggcggcggc gagttcccgt accgcccgcg cgtccgcccc cgtcacgcgc accagatgac
     7621 tgtcctgcac caccaccgcg ccacgctcca cccgtggcgg ctcctccacg atcacatgcg
     7681 cgttcacccc acccatcccg aacgcgctca ccgcaccacg ccgcggaccc tcctcacgcc
     7741 cccacaccca cgcacgatcc accagaaaga acggcgaatc ctcaaaccgg atgtgatcgt
     7801 tcggccgccg cacatgcaac gaacccggaa ccaccccatg ctccatcgcc aacaacacct
     7861 t
//
