LOCUS       NZ_MNPQ01000037        27559 bp    DNA     linear   CON 11-AUG-2024
DEFINITION  Streptomyces albidoflavus strain OsiLf-2 Scaffold33_1, whole genome
            shotgun sequence.
ACCESSION   NZ_MNPQ01000037
VERSION     NZ_MNPQ01000037.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces albidoflavus
  ORGANISM  Streptomyces albidoflavus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
REFERENCE   1  (bases 1 to 27559)
  AUTHORS   Zhu,Y., Zeng,X., Zeng,J. and Liu,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2016) College of Biology, Hunan University, 1
            Denggao Road, Changsha, Hunan 410082, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. FEBRUARY-2016
            Genome Coverage                   :: 140.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001865795.1-RS_2024_08_11
            Annotation Date                   :: 08/11/2024 02:37:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,098
            CDSs (total)                      :: 6,022
            Genes (coding)                    :: 5,927
            CDSs (with protein)               :: 5,927
            Genes (RNA)                       :: 76
            rRNAs                             :: 3, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 44 of 95
            Pseudo Genes (incomplete)         :: 58 of 95
            Pseudo Genes (internal stop)      :: 9 of 95
            Pseudo Genes (multiple problems)  :: 15 of 95
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:10:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 27559
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MNPQ01000037.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..27559
                     /collection_date="2015-11"
                     /db_xref="taxon:1886"
                     /geo_loc_name="China:Changsha, Hunan"
                     /host="rice"
                     /isolation_source="rice"
                     /lat_lon="28.4196 N 114.02870000 E"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces albidoflavus"
                     /strain="OsiLf-2"
                     /submitter_seqid="Scaffold33_1"
     region          1..27559
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..27559
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27559
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[2393:8534](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2394..8534
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     gene            16..2355
                     /locus_tag="BGV78_RS29665"
     CDS             16..2355
                     /NRPS_PKS="Domain: PKS_KR (414-594). E-value: 4.5e-35.
                     Score: 113.2. Matches aSDomain:
                     nrpspksdomains_BGV78_RS29665_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (662-738). E-value: 1.3e-12.
                     Score: 39.9. Matches aSDomain:
                     nrpspksdomains_BGV78_RS29665_PKS_PP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF020243.4"
                     /locus_tag="BGV78_RS29665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_079177550.1"
                     /sec_met_domain="mod_KS (E-value: 4.2e-17, bitscore: 52.3,
                     seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 5.6e-35, bitscore:
                     111.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4e-11, bitscore:
                     33.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHGVVPGSLHVRRPNDHIRFEDSPFFLVDRPWVWGREGGPRRGA
                     VSAFGMGGVNAHVIVEEPPRVERGAVVVQDSHLVRVTGADERAVRELAAAYADRFATSR
                     GPWDTADLCHTANVGRSPQEYVTAVHGRDAAELAENLRAVAAGRLPVGVAGSGTRDPDP
                     APTGHAALAELVRTGYTGVDWPALSVPGARTTDLPTYPFAPGRHWHMHTEVTAPAEDTP
                     PEAYRATWREEALPQEAQAAPGTVRLVVTDPALHEALTAELRLYGAHVAGTEAEADTVL
                     MVDATPPGREPDLSTFWARVADMLKALPPHGRLLWAACHGAALRPGEHASLRPGTAAQA
                     MAVAAACAESRIAHAVVHLDPSEPAEARARVLAAEYAALRQGGESTAAAHRAGVRYVPD
                     TSPVRPGRAYEVRPDGYYLVTGGLGAIGRRLVERLIDRGARHIGIVGRSALDPGRSQTL
                     RALATRAEVVYRSCDVADAPALTAVVGELDARWGRLRGVVHCSGGVNAFGAMRRRPWAD
                     AARVVTPKTDGSLHAVRLAQDRGADFAVLTSSLAGTHADAGRGLVDYSLANAYQLALAE
                     REHGPGTAVTAHAWPNWTGVGMAADAAFAAAHSLDATEAEAAFFGHLLTGGAVVLPGHA
                     PAAPPASPADTPETREPGPGTRTVIPAPATGRDRTALRAHVRDAFLHVLGDDPGDRPLR
                     GLGLDSLVIAELATALEQRAGRTVDPSLLMRARTADELAAELAATAAGPPEAGAGPAVP
                     ADATGATALSLLLRPLLTDGGDGVTP"
     aSDomain        1258..1797
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS29665_PKS_KR.1"
                     /evalue="4.50E-35"
                     /label="BGV78_RS29665_PKS_KR.1"
                     /locus_tag="BGV78_RS29665"
                     /protein_end="594"
                     /protein_start="414"
                     /score="113.2"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GYYLVTGGLGAIGRRLVERLIDRGARHIGIVGRSALDPGRSQTLR
                     ALATRAEVVYRSCDVADAPALTAVVGELDARWGRLRGVVHCSGGVNAFGAMRRRPWADA
                     ARVVTPKTDGSLHAVRLAQDRGADFAVLTSSLAGTHADAGRGLVDYSLANAYQLALAER
                     EHGPGTAVTAHAWPNWT"
     aSModule        1258..2229
                     /domains="nrpspksdomains_BGV78_RS29665_PKS_KR.1"
                     /domains="nrpspksdomains_BGV78_RS29665_PKS_PP.1"
                     /incomplete
                     /locus_tags="BGV78_RS29665"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       1264..1359
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS29665_0001"
                     /evalue="4.00E-12"
                     /label="PKSI-KR_m1"
                     /locus_tag="BGV78_RS29665"
                     /protein_end="448"
                     /protein_start="416"
                     /score="38.7"
                     /tool="antismash"
                     /translation="YLVTGGLGAIGRRLVERLIDRGARHIGIVGRS"
     CDS_motif       1639..1743
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS29665_0002"
                     /evalue="3.60E-04"
                     /label="PKSI-KR_m4"
                     /locus_tag="BGV78_RS29665"
                     /protein_end="576"
                     /protein_start="541"
                     /score="13.0"
                     /tool="antismash"
                     /translation="DFAVLTSSLAGTHADAGRGLVDYSLANAYQLALAE"
     aSDomain        2002..2229
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS29665_PKS_PP.1"
                     /evalue="1.30E-12"
                     /label="BGV78_RS29665_PKS_PP.1"
                     /locus_tag="BGV78_RS29665"
                     /protein_end="738"
                     /protein_start="662"
                     /score="39.9"
                     /tool="antismash"
                     /translation="PATGRDRTALRAHVRDAFLHVLGDDPGDRPLRGLGLDSLVIAELA
                     TALEQRAGRTVDPSLLMRARTADELAAELAA"
     gene            2394..8534
                     /locus_tag="BGV78_RS31980"
     CDS             2394..8534
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (7-426). E-value:
                     5.1e-133. Score: 436.0. Matches aSDomain:
                     nrpspksdomains_BGV78_RS31980_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_DH (717-861). E-value: 8.2e-10.
                     Score: 31.2. Matches aSDomain:
                     nrpspksdomains_BGV78_RS31980_PKS_DH.1"
                     /NRPS_PKS="Domain: ACP (1044-1096). E-value: 4.3e-17.
                     Score: 54.2. Matches aSDomain:
                     nrpspksdomains_BGV78_RS31980_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (1170-1579).
                     E-value: 1.4e-143. Score: 470.8. Matches aSDomain:
                     nrpspksdomains_BGV78_RS31980_PKS_KS.2"
                     /NRPS_PKS="Domain: PKS_AT (1677-1973). E-value: 2.2e-90.
                     Score: 295.0. Matches aSDomain:
                     nrpspksdomains_BGV78_RS31980_PKS_AT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     tra_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508348.1"
                     /locus_tag="BGV78_RS31980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I polyketide synthase"
                     /protein_id="WP_071339535.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 3.4e-68, bitscore:
                     220.2, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 1.6e-133, bitscore:
                     436.0, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1e-11, bitscore:
                     35.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 4.5e-148, bitscore:
                     483.9, seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 6.8e-91, bitscore: 295.0,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEEDRRIAVIGLAARLPGAEDAADLTEMLRHDTVEVDEVPASRW
                     RRDLHLGDGPHQGSHHRGAFLLDPFSFDHTAFGLTADQARSLDPQQRTMLEVGARALED
                     SGYLRTRRRLNAGVFVGARMNAYGFDQGRGLGGAPQTAAGPAALWGRSQNFMAAWLSDR
                     FDLSGPSLVVDTACSSSLTAVWLACQSLSAGACDLAVVGGVDLLIDPLTFVLLSRNGAL
                     SPDGLCRTFDSRADGYVPGEGAVALVLKPLRAALADRDLVLGAIDAAAVNNDGATMGVT
                     TPSLDAQVELLGKVYETIDPATVQYVEAHGTGTAIGDPIEARALTEVFGRAGVPRGSVA
                     LGSLKRRIGHLHSASGLAGLAKILVLLREGLVPALGVERPNPRLDLANSPFHLPAEPGP
                     WPSVPVRRAAVSGFGFGGTNAHVVAQAVAVPEAQIPAGPVTPTVHVLPLSATTAHGLRE
                     LAAQWLQFLPSAAEDLHHVCATARLARPHHGERLAVCGTDAAALAQALRTWLLRPGGTE
                     EPPRTTVPVRPEAAATPPAWLTALRGATPAVDEVLGLFETATGRRLETFSGELLRLSTA
                     VALTVALRAAGLPEDAVELPAGWTAVTDFAWGRVPLEQALADVLRHDGEPSRTAEDAAR
                     RDDGELCARLAAVRDAPGAAAVTAAVTAELFAAGHAIDWMALQVGRPWHKRLLPVAQPD
                     GPALDLPEPLRSAEPGTPTADAPEEADAGGHAFARVFGPGETPIAQHAVYRTVMLPGVA
                     WFDFLREGAALRGVPFHGVADVLFHRPLIPAGASRVVCRVAGDGAFTVEDAESREAFVT
                     GRYLTGRTAEPSPEPVASLLESCAEIHAGSGLYRWLRRIGYHHGRYYRNISWVAGLPDG
                     GTLARVEGARQQPLNPAGTALFPGLLDSVTIAAINPDNPVFGAGDAAAFIPLSAGRVEV
                     YGPLEEAAYVRTRTAFWNDEACRVTQTVTDATGRPLLTFTDMASKRVPAAAFGDAPEAL
                     PSAPSAPSAPAPAPSPRPAPERAAPPTQPAAPTSPASAPARLLTWFLALTGTTAEDADT
                     EFLSAGFDSVGLVSLSERLSDEHGLTLYPTVFFEYPTPRRFAEFLLTEAPAFADSPAVT
                     GAGGTQDSTARPPEPPAPAPPPPPPPPAVPPAAPPNPAASEPPARPRRTPARPTPQEPS
                     HTRDIAVVGAAVRLPSARGLAEFTDLLDEGRDTVRGLPQERGGQGEGAGPYASFLDRVD
                     EFDPAPFRISPREAPLIDPQARIVYETVWEALEDGGRTGRRAEDSTTGLWIAYSHDHYH
                     EERVRHGAHEGRGLGLEAMIANRLSYLMDWHGPSALVNTLCSSSLVALHTAVQHLRSGD
                     IDTAVIGAVHAALSPEYFRSMGDLMALSPRHRCRAFDDTADGFVPGEGAVAVVLRRYTD
                     AERDGDRVRGLVKGAAVNHGGRTTRYSAPSPKAQRDVVAAALNDAAVPPETIDLVEAHG
                     TGTRLGDPIEIDGLTRAWRAHTDRSQFCAIGSLKSNIGHLEPAAGLAGLVKILLAMESE
                     RIPATLHVTRPNDHIRFEGTPFHLADRARPWPRGERPRRAALSAFGMGGVNAHVIVEEP
                     PPAADRHPLAQDSHLLRAGAADEQTLRTLAGAYADQLARTPAEGIGDFTRTANTARATH
                     RHRVVVHGTTGAELAERLAAVAAGTTPTVRHTDRTTTAFLFTGQGSQYAGMGRGLLATE
                     PHFRDALHECADLLAPHTDVPLLDLLHGDARHLLDQTRYAQIGIVSIQVALVRYLAAAD
                     VRPDTVAGHSLGELTAAWTAGVLTLPDLLRLTAERGRLMQAAPATGAMAAAHTDARTLA
                     DTLEAYPGIEIAAYNAPRLQTVTGPAEALERLRAHAAFTVRPLTVSHAFHSALMDGAVG
                     PFREAVAKTPLAPPTLPFASTLTGSWHTPATATDPAHWARAVREPVRFAEAVTTLHGTG
                     PHTVWEIGPHPHLIPLARATLAAPGATGAGPAWIATLRRDHADQVQLHAALAAHHDHTG
                     ADLDWAALHDGKDQRVTTLPTYPFHRRRFWLPAEDRDHATTSTSDDTRRPEHHG"
     aSDomain        2415..3671
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS31980_PKS_KS.1"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="5.10E-133"
                     /label="BGV78_RS31980_PKS_KS.1"
                     /locus_tag="BGV78_RS31980"
                     /protein_end="426"
                     /protein_start="7"
                     /score="436.0"
                     /specificity="transATor: (unknown)"
                     /tool="antismash"
                     /translation="IAVIGLAARLPGAEDAADLTEMLRHDTVEVDEVPASRWRRDLHLG
                     DGPHQGSHHRGAFLLDPFSFDHTAFGLTADQARSLDPQQRTMLEVGARALEDSGYLRTR
                     RRLNAGVFVGARMNAYGFDQGRGLGGAPQTAAGPAALWGRSQNFMAAWLSDRFDLSGPS
                     LVVDTACSSSLTAVWLACQSLSAGACDLAVVGGVDLLIDPLTFVLLSRNGALSPDGLCR
                     TFDSRADGYVPGEGAVALVLKPLRAALADRDLVLGAIDAAAVNNDGATMGVTTPSLDAQ
                     VELLGKVYETIDPATVQYVEAHGTGTAIGDPIEARALTEVFGRAGVPRGSVALGSLKRR
                     IGHLHSASGLAGLAKILVLLREGLVPALGVERPNPRLDLANSPFHLPAEPGPWPSVPVR
                     RAAVSGFGFGGTNAHVVAQA"
     aSModule        2415..5681
                     /complete
                     /domains="nrpspksdomains_BGV78_RS31980_PKS_KS.1"
                     /domains="nrpspksdomains_BGV78_RS31980_PKS_DH.1"
                     /domains="nrpspksdomains_BGV78_RS31980_ACP.1"
                     /locus_tags="BGV78_RS31980"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       2895..2942
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS31980_0001"
                     /evalue="2.60E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="BGV78_RS31980"
                     /protein_end="183"
                     /protein_start="167"
                     /score="19.4"
                     /tool="antismash"
                     /translation="GPSLVVDTACSSSLTA"
     CDS_motif       3084..3122
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS31980_0002"
                     /evalue="4.70E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="BGV78_RS31980"
                     /protein_end="243"
                     /protein_start="230"
                     /score="13.3"
                     /tool="antismash"
                     /translation="FDSRADGYVPGEG"
     CDS_motif       3309..3356
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS31980_0003"
                     /evalue="1.60E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="BGV78_RS31980"
                     /protein_end="321"
                     /protein_start="305"
                     /score="13.7"
                     /tool="antismash"
                     /translation="YVEAHGTGTAIGDPIE"
     CDS_motif       3417..3461
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS31980_0004"
                     /evalue="1.70E-01"
                     /label="PKSI-KS_m6"
                     /locus_tag="BGV78_RS31980"
                     /protein_end="356"
                     /protein_start="341"
                     /score="5.6"
                     /tool="antismash"
                     /translation="GSLKRRIGHLHSASG"
     CDS_motif       3615..3689
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS31980_0005"
                     /evalue="2.60E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="BGV78_RS31980"
                     /protein_end="432"
                     /protein_start="407"
                     /score="-1.8"
                     /tool="antismash"
                     /translation="AAVSGFGFGGTNAHVVAQAVAVPEA"
     aSDomain        4545..4976
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS31980_PKS_DH.1"
                     /evalue="8.20E-10"
                     /label="BGV78_RS31980_PKS_DH.1"
                     /locus_tag="BGV78_RS31980"
                     /protein_end="861"
                     /protein_start="717"
                     /score="31.2"
                     /tool="antismash"
                     /translation="EEADAGGHAFARVFGPGETPIAQHAVYRTVMLPGVAWFDFLREGA
                     ALRGVPFHGVADVLFHRPLIPAGASRVVCRVAGDGAFTVEDAESREAFVTGRYLTGRTA
                     EPSPEPVASLLESCAEIHAGSGLYRWLRRIGYHHGRYYRN"
     aSDomain        5526..5681
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS31980_ACP.1"
                     /evalue="4.30E-17"
                     /label="BGV78_RS31980_ACP.1"
                     /locus_tag="BGV78_RS31980"
                     /protein_end="1096"
                     /protein_start="1044"
                     /score="54.2"
                     /tool="antismash"
                     /translation="DADTEFLSAGFDSVGLVSLSERLSDEHGLTLYPTVFFEYPTPRRF
                     AEFLLTE"
     aSDomain        5904..7130
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS31980_PKS_KS.2"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="1.40E-143"
                     /label="BGV78_RS31980_PKS_KS.2"
                     /locus_tag="BGV78_RS31980"
                     /protein_end="1579"
                     /protein_start="1170"
                     /score="470.8"
                     /specificity="transATor: (unknown)"
                     /tool="antismash"
                     /translation="IAVVGAAVRLPSARGLAEFTDLLDEGRDTVRGLPQERGGQGEGAG
                     PYASFLDRVDEFDPAPFRISPREAPLIDPQARIVYETVWEALEDGGRTGRRAEDSTTGL
                     WIAYSHDHYHEERVRHGAHEGRGLGLEAMIANRLSYLMDWHGPSALVNTLCSSSLVALH
                     TAVQHLRSGDIDTAVIGAVHAALSPEYFRSMGDLMALSPRHRCRAFDDTADGFVPGEGA
                     VAVVLRRYTDAERDGDRVRGLVKGAAVNHGGRTTRYSAPSPKAQRDVVAAALNDAAVPP
                     ETIDLVEAHGTGTRLGDPIEIDGLTRAWRAHTDRSQFCAIGSLKSNIGHLEPAAGLAGL
                     VKILLAMESERIPATLHVTRPNDHIRFEGTPFHLADRARPWPRGERPRRAALSAFGMGG
                     VNAHVIVEEP"
     aSModule        5904..8312
                     /domains="nrpspksdomains_BGV78_RS31980_PKS_KS.2"
                     /domains="nrpspksdomains_BGV78_RS31980_PKS_AT.1"
                     /incomplete
                     /locus_tags="BGV78_RS31980"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       6339..6386
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS31980_0006"
                     /evalue="2.30E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="BGV78_RS31980"
                     /protein_end="1331"
                     /protein_start="1315"
                     /score="13.6"
                     /tool="antismash"
                     /translation="GPSALVNTLCSSSLVA"
     CDS_motif       6528..6566
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS31980_0007"
                     /evalue="4.30E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="BGV78_RS31980"
                     /protein_end="1391"
                     /protein_start="1378"
                     /score="10.4"
                     /tool="antismash"
                     /translation="FDDTADGFVPGEG"
     CDS_motif       6762..6806
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS31980_0008"
                     /evalue="4.00E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="BGV78_RS31980"
                     /protein_end="1471"
                     /protein_start="1456"
                     /score="12.6"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPIE"
     CDS_motif       6867..6911
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS31980_0009"
                     /evalue="4.40E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="BGV78_RS31980"
                     /protein_end="1506"
                     /protein_start="1491"
                     /score="9.9"
                     /tool="antismash"
                     /translation="GSLKSNIGHLEPAAG"
     CDS_motif       7422..7475
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS31980_0010"
                     /evalue="1.30E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="BGV78_RS31980"
                     /protein_end="1694"
                     /protein_start="1676"
                     /score="17.6"
                     /tool="antismash"
                     /translation="FLFTGQGSQYAGMGRGLL"
     aSDomain        7425..8312
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS31980_PKS_AT.1"
                     /evalue="2.20E-90"
                     /label="BGV78_RS31980_PKS_AT.1"
                     /locus_tag="BGV78_RS31980"
                     /protein_end="1973"
                     /protein_start="1677"
                     /score="295.0"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQYAGMGRGLLATEPHFRDALHECADLLAPHTDVPLLDL
                     LHGDARHLLDQTRYAQIGIVSIQVALVRYLAAADVRPDTVAGHSLGELTAAWTAGVLTL
                     PDLLRLTAERGRLMQAAPATGAMAAAHTDARTLADTLEAYPGIEIAAYNAPRLQTVTGP
                     AEALERLRAHAAFTVRPLTVSHAFHSALMDGAVGPFREAVAKTPLAPPTLPFASTLTGS
                     WHTPATATDPAHWARAVREPVRFAEAVTTLHGTGPHTVWEIGPHPHLIPLARATLAAPG
                     ATGAGPAWIATLRRD"
     CDS_motif       7662..7781
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS31980_0011"
                     /evalue="1.80E-18"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="BGV78_RS31980"
                     /protein_end="1796"
                     /protein_start="1756"
                     /score="58.6"
                     /tool="antismash"
                     /translation="VRPDTVAGHSLGELTAAWTAGVLTLPDLLRLTAERGRLMQ"
     gene            8527..9648
                     /locus_tag="BGV78_RS29675"
     CDS             8527..9648
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018896346.1"
                     /locus_tag="BGV78_RS29675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA alkylation repair protein"
                     /protein_id="WP_071339536.1"
                     /transl_table=11
                     /translation="MASEYGLKRHFNGEAARLIGGKIRALHPEFDVEAYAGEVEQRIPG
                     KELKDRVLVLAEGLRTRLPGGYPDALPLLLGTLGDELAEGEGMFNTSWYLMPVARFVEE
                     YGLDHPELSLDAIEAITRCHTGEYAIRPYVEQHHPRTMKRVAEWALSPSHNVRRLASEG
                     VRPRLPWARTLDIFVQDPAPVLAILEPLRSDPSEYVRKSVANNLNDIAKDHPETALATA
                     LRWLEESPTPETEWTVKHGLRTLVKKGNQQALALLGATGGEHVQVDRLSLTPKAVTVGD
                     TVVIDVDLANTDDRPHSVTVDYVVHHVRKNGRSIPKVFKLTTLELAAGERRSLRKSHPL
                     REVQTRKYYPGEHAVDIQVNGLVKATERFGLRT"
     gene            9645..13391
                     /locus_tag="BGV78_RS29680"
     CDS             9645..13391
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: PKS_DH (9-138). E-value: 9.2e-14. Score:
                     44.1. Matches aSDomain:
                     nrpspksdomains_BGV78_RS29680_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (454-624). E-value: 4.1e-45.
                     Score: 145.9. Matches aSDomain:
                     nrpspksdomains_BGV78_RS29680_PKS_KR.1"
                     /NRPS_PKS="Domain: PP-binding (689-748). E-value: 8.3e-14.
                     Score: 43.7. Matches aSDomain:
                     nrpspksdomains_BGV78_RS29680_PP-binding.1"
                     /NRPS_PKS="Domain: Aminotran_1_2 (897-1236). E-value:
                     4.3e-56. Score: 182.5. Matches aSDomain:
                     nrpspksdomains_BGV78_RS29680_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109: 8-amino-7-oxononanoate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946459.1"
                     /locus_tag="BGV78_RS29680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_071339537.1"
                     /sec_met_domain="adh_short (E-value: 1e-39, bitscore:
                     126.7, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.8e-13, bitscore:
                     41.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.4e-56, bitscore:
                     182.5, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 1.3e-07, bitscore:
                     21.1, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 5.3e-08,
                     bitscore: 22.7, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGARVHLTAADPLVADHRIGGTPVVAAAAQIDLLLRACDAARPD
                     RVRTLEHVAFRAPLRVTGPGAVLDVTTDDGRCALRCDGTEYATARHRDASLPPPRYLDV
                     AGLGAGCAEPVPLAGLDAWRRASGITYGPAYRAIRSARRGPGRILAVVRAGDDTSCAPA
                     FVPPPLLDSVFQALGLLDAGAAGACLPWYVGRITARRRITGTVLALVEREAGEEAANGA
                     VRGRATVCNQQGEVLLELDRITLKSAAPPAPDPLPSPTTHLIETVGWRRSETAGPPPDG
                     EGAVLLVAADDRTPAGLRPDIRLTPGELTPERLDEALAPHTLHEVVYVAPEGLSGAGPA
                     TEALQQVFALVRHLAARPPMPRLLIVTTGAHQVSGDEAPDPFMTALWGLGRTLRVEHPR
                     TTVRLADLEPGTTAPLPAIPYGQDELALRHGTWHTPTTEPQQPLPVTPPRLSGGRFLIT
                     GGMGAIGLRVAELLADAGCAHLTLVGRTVPDEGERRHRLDRLGTRCALDIVAADVRDLP
                     ALLADAPRFDGVFHTAGVLRDGLARGLTPQRIAEVLGPKAGGAHALAELTAAHEPPGFV
                     ALFSSVAAVRANLGQSAYAAANAYLDGFAARQRAAGRPWYSLGWGLWTVGMGEDVAPRA
                     ATHGVPALTPDDGAALLRTVLGRPPAHYVLSATAQAKGEPMTAAVEPETGLWPHLAAAL
                     RKILHVTEVSPDDDLLEMGLDSMMAVELAAALSGSGLDIDPMVFFEHSRVSLLLASLEK
                     LPRSGQEPEATVPAPAPAPAVAPVAPAPPPPPAPEPHRPAPAPAGTFVPDWDRYRTPAP
                     GPARPAPAGRAPRPPRPADDRAAARVPRRTLPGRLRNASGGSFLDRRIDALSEEDRLIV
                     ARDEYFYEPVIEQAEGARIKFDGRWFLNFASYSYLGLIGHDYIDQRALDAVERHGTGAH
                     GVRLLAGTLHLHRELELALARFLGAEDAIVYSSGYMANVATVGALVGPGDVIIGDVYNH
                     ASILDGYRLSGADVITYAHNDLADLERALKKAGDAGRLVVTDAVFSMDGDVADLPGIVD
                     LCERYDAPLMVDEAHSLGVLGDTGRGITEHFGLDPDRVDVKMGTLSKTVPSAGGYVAGS
                     RDLVFALKNNARGWMFSAAATPAQIAAAKAAIEVIEAAPERVRELRARTTRYRERLRAL
                     GFDTLTGETPVVPVICGSAEQAGAMARLCQLDGLFVQPIVYPAVPRTLPRLRTIVNLDH
                     SEADLDTAVDVLEKAGRACGLLP"
     aSDomain        9672..10058
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS29680_PKS_DH.1"
                     /evalue="9.20E-14"
                     /label="BGV78_RS29680_PKS_DH.1"
                     /locus_tag="BGV78_RS29680"
                     /protein_end="138"
                     /protein_start="9"
                     /score="44.1"
                     /tool="antismash"
                     /translation="AADPLVADHRIGGTPVVAAAAQIDLLLRACDAARPDRVRTLEHVA
                     FRAPLRVTGPGAVLDVTTDDGRCALRCDGTEYATARHRDASLPPPRYLDVAGLGAGCAE
                     PVPLAGLDAWRRASGITYGPAYRAI"
     aSModule        9672..13352
                     /domains="nrpspksdomains_BGV78_RS29680_PKS_DH.1"
                     /domains="nrpspksdomains_BGV78_RS29680_PKS_KR.1"
                     /domains="nrpspksdomains_BGV78_RS29680_PP-binding.1"
                     /domains="nrpspksdomains_BGV78_RS29680_Aminotran_1_2.1"
                     /incomplete
                     /locus_tags="BGV78_RS29680"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       9690..9758
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS29680_0001"
                     /evalue="1.80E-05"
                     /label="PKSI-DH_m2"
                     /locus_tag="BGV78_RS29680"
                     /protein_end="38"
                     /protein_start="15"
                     /score="17.4"
                     /tool="antismash"
                     /translation="ADHRIGGTPVVAAAAQIDLLLRA"
     aSDomain        11007..11516
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS29680_PKS_KR.1"
                     /evalue="4.10E-45"
                     /label="BGV78_RS29680_PKS_KR.1"
                     /locus_tag="BGV78_RS29680"
                     /protein_end="624"
                     /protein_start="454"
                     /score="145.9"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="FLITGGMGAIGLRVAELLADAGCAHLTLVGRTVPDEGERRHRLDR
                     LGTRCALDIVAADVRDLPALLADAPRFDGVFHTAGVLRDGLARGLTPQRIAEVLGPKAG
                     GAHALAELTAAHEPPGFVALFSSVAAVRANLGQSAYAAANAYLDGFAARQRAAGRPWYS
                     LGWGLWT"
     CDS_motif       11010..11102
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS29680_0002"
                     /evalue="1.40E-10"
                     /label="PKSI-KR_m1"
                     /locus_tag="BGV78_RS29680"
                     /protein_end="486"
                     /protein_start="455"
                     /score="33.8"
                     /tool="antismash"
                     /translation="LITGGMGAIGLRVAELLADAGCAHLTLVGRT"
     CDS_motif       11367..11471
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS29680_0003"
                     /evalue="2.50E-13"
                     /label="PKSI-KR_m4"
                     /locus_tag="BGV78_RS29680"
                     /protein_end="609"
                     /protein_start="574"
                     /score="42.5"
                     /tool="antismash"
                     /translation="FVALFSSVAAVRANLGQSAYAAANAYLDGFAARQR"
     aSDomain        11712..11888
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS29680_PP-binding.1"
                     /evalue="8.30E-14"
                     /label="BGV78_RS29680_PP-binding.1"
                     /locus_tag="BGV78_RS29680"
                     /protein_end="748"
                     /protein_start="689"
                     /score="43.7"
                     /tool="antismash"
                     /translation="LAAALRKILHVTEVSPDDDLLEMGLDSMMAVELAAALSGSGLDID
                     PMVFFEHSRVSLLL"
     aSDomain        12336..13352
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS29680_Aminotran_1_2.1"
                     /evalue="4.30E-56"
                     /label="BGV78_RS29680_Aminotran_1_2.1"
                     /locus_tag="BGV78_RS29680"
                     /protein_end="1236"
                     /protein_start="897"
                     /score="182.5"
                     /tool="antismash"
                     /translation="LNFASYSYLGLIGHDYIDQRALDAVERHGTGAHGVRLLAGTLHLH
                     RELELALARFLGAEDAIVYSSGYMANVATVGALVGPGDVIIGDVYNHASILDGYRLSGA
                     DVITYAHNDLADLERALKKAGDAGRLVVTDAVFSMDGDVADLPGIVDLCERYDAPLMVD
                     EAHSLGVLGDTGRGITEHFGLDPDRVDVKMGTLSKTVPSAGGYVAGSRDLVFALKNNAR
                     GWMFSAAATPAQIAAAKAAIEVIEAAPERVRELRARTTRYRERLRALGFDTLTGETPVV
                     PVICGSAEQAGAMARLCQLDGLFVQPIVYPAVPRTLPRLRTIVNLDHSEADLDTAVDV"
     misc_feature    13457..13471
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.76"
                     /tool="antismash"
     gene            13457..13765
                     /locus_tag="BGV78_RS29685"
     CDS             13457..13765
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946458.1"
                     /locus_tag="BGV78_RS29685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_003946458.1"
                     /transl_table=11
                     /translation="MTDIDAAAFFAAVLKTIASTRNNGAGPEEHTQGVVEPAGRIRAVE
                     QEAADRRLTTGEAGEVLDLLETTFRTKRTPDEEREYYLQYIEKVSGVSRASLGVSAP"
     gene            13762..14910
                     /locus_tag="BGV78_RS29690"
     CDS             13762..14910
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639193.1"
                     /locus_tag="BGV78_RS29690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class II histone deacetylase"
                     /protein_id="WP_071339538.1"
                     /transl_table=11
                     /translation="MNAPRAAWYSHELCHWHDPGAGSGYLPVGPGIEPLRQFAVDPDLR
                     RAEGLVRASGVMDHFTAVTPLPATDEELLRVHVPEHLERVEAASAAGAGDAGVYAHVNY
                     HSAHAARLAAGACAQAATAVVEGRFERAYCLVRPPGHHAEPDRAMALCLYNNLAVAART
                     AQRHGVRRVLVLDWDVHHGNGLQRVFYDDPDVLYISLHQDGLFPAASGRVLETGTGKGT
                     GRTLNVPLPAGSGHGAYLAALDQIVEPAARAFRPELILVAAGVDAGAHDPMGRMMCTSR
                     TFHALSSALCRLADELAGGRIVFAHEGGYSAWYQPTLVLATAAAIAGLPAPHDPFLHAL
                     EHLPGQRLQPHQSRVLTHLRDHHPLLTGQGTPVGAAPGGADG"
     gene            14903..15745
                     /locus_tag="BGV78_RS29695"
     CDS             14903..15745
                     /NRPS_PKS="Domain: Thioesterase (20-243). E-value: 1.1e-42.
                     Score: 139.0. Matches aSDomain:
                     nrpspksdomains_BGV78_RS29695_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414033.1"
                     /locus_tag="BGV78_RS29695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thioesterase II family protein"
                     /protein_id="WP_071339539.1"
                     /sec_met_domain="Thioesterase (E-value: 2.8e-40, bitscore:
                     129.2, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDWWLRAGAGAGATGERARRRVVALPHAGGWPSAFRSWWQVLPP
                     DAELLVAQLPGRGARLGEPPLTSVEPLVEALSRELAERDPLPYTVVGHSFGSVLGYELT
                     RAMEQKGLAPDLLAVSARQPPCFPSLPPFAHLRSDAQLLEHLTEIGGMAPQLMTRPELV
                     QPALRAIRADLEAMERHQRPLTGTGVPILALGAVDDPVVVAERLHLWSLETTGGFHRSL
                     YTGGHFYLYAHANAAAIARRLLADRPGPTAGHPAPPTPGRPVPVPDGVPAPSPRKETP"
     aSDomain        14963..15631
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BGV78_RS29695_Thioesterase.1"
                     /evalue="1.10E-42"
                     /label="BGV78_RS29695_Thioesterase.1"
                     /locus_tag="BGV78_RS29695"
                     /protein_end="243"
                     /protein_start="20"
                     /score="139.0"
                     /tool="antismash"
                     /translation="RRVVALPHAGGWPSAFRSWWQVLPPDAELLVAQLPGRGARLGEPP
                     LTSVEPLVEALSRELAERDPLPYTVVGHSFGSVLGYELTRAMEQKGLAPDLLAVSARQP
                     PCFPSLPPFAHLRSDAQLLEHLTEIGGMAPQLMTRPELVQPALRAIRADLEAMERHQRP
                     LTGTGVPILALGAVDDPVVVAERLHLWSLETTGGFHRSLYTGGHFYLYAHANAAAIARR
                     L"
     misc_feature    15062..15064
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       15161..15220
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BGV78_RS29695_0001"
                     /evalue="2.50E-06"
                     /label="NRPS-te1"
                     /locus_tag="BGV78_RS29695"
                     /protein_end="106"
                     /protein_start="86"
                     /score="20.0"
                     /tool="antismash"
                     /translation="PYTVVGHSFGSVLGYELTRA"
     gene            15742..17298
                     /locus_tag="BGV78_RS29700"
     CDS             15742..17298
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018469564.1"
                     /locus_tag="BGV78_RS29700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_071339540.1"
                     /transl_table=11
                     /translation="MSTIADIPAKAGPKEWLGLAVLALPTLLLSIDVSVLHLAVPHISE
                     ALNPSASQMLWIIDIYGFLIAGFLVTMGTLGDRIGRRKLLLIGAAAFGLASVAAAYADD
                     PALLIAARALLGVAGATLMPSTLALISNMFADARQRGMAIAIWVTMFSVGIALGPVVGG
                     AMLEYFWWGSVFLLGVPIMGLLLVAGPVLLPEYRDENAGRLDLTSALLSLVAILPVIYG
                     LKELAKDGLAVLPLLTLVAGAALAVVFVRRQRTLDSPLMDFRLFRNPTFRTALVTLLLS
                     MLVAGGTYLLVTQYLQLVGGLTPMTAGLYLLPAAFALIVTSVVSPIAASRFRPAHVVAA
                     GLVVSALGHVMLATADSTSGIAQVVTGFAFVYGGGGPLVALGTDIVVGSAPPEQAGSAS
                     AVSETSTELGMALGVATLGSLGAAVYRAGVELPPGVGDGAGDTLAGALDAAKSLPAEVA
                     SALADSGRAAFTDGMNAVGAVGTLLALGSAVMVAMVIKSPPTGAGEEPATGDEPLVKAA
                     E"
     gene            complement(17383..17811)
                     /locus_tag="BGV78_RS29705"
     CDS             complement(17383..17811)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639187.1"
                     /locus_tag="BGV78_RS29705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VOC family protein"
                     /protein_id="WP_033240910.1"
                     /transl_table=11
                     /translation="MAPSALTSFYPVLCTRKLSESAAFYKNLFGFETTFENEWYVSLRR
                     SEPPHQELALVDAGHPSVPEGFRQPVQGVLLNFEVADVDAEYARLVDGAGLRPQLPLRS
                     EDFGQRHFIVAAPDGVLVDVISPIEPSAEYADAYQDPS"
     gene            18029..18382
                     /locus_tag="BGV78_RS29710"
     CDS             18029..18382
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946453.1"
                     /locus_tag="BGV78_RS29710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VOC family protein"
                     /protein_id="WP_226660338.1"
                     /transl_table=11
                     /translation="MIRTSRIEESRAFYTGLFGFKVTYETPWYVDLARPALPPRELSLI
                     DLGHPAVPEAQRLPVRAVRIVLESEAGEAELQHALSRAGFDARRVFRPPGRAPGALTLM
                     DPSGVRVHVVAPA"
     misc_feature    18200..18202
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18429..19016
                     /locus_tag="BGV78_RS29715"
     CDS             18429..19016
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414039.1"
                     /locus_tag="BGV78_RS29715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_008414039.1"
                     /transl_table=11
                     /translation="MPARIDPDTAAAVMRAAGLEPMEPYPGANVAWNCRCLKGAHGVAP
                     TFTSVRTGTSSGCRHCGRTAAGERRRAAGQARAEADMRAAGFEPLDPYPGARMRWRCLH
                     TACGRVVHPRLFQIRTGGGGCLACAGRAPVEPTAAEAEMRAIGMEPLEPFPGRVRDPWS
                     CRCTRCGHVGTPTLNNIRRGQGGCYPCAHRGR"
     gene            complement(19026..19616)
                     /locus_tag="BGV78_RS29720"
     CDS             complement(19026..19616)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414041.1"
                     /locus_tag="BGV78_RS29720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_018469562.1"
                     /transl_table=11
                     /translation="MPQGVRAQQRELTRQALVRESRRLFSTLGYGAVGLSEIVAAAGVT
                     KGALYHHFSSKAELFRVVLEQAQQEVAERIAATADARESSWEQLLVGCEAFLGASTDPA
                     IQRIMLIDGPAVLGWAEWREMNEATSGRHLAEVLAVLIEEGAIPAQPVEPLTHLLSGAM
                     NEAALWLAASSDPADLADATAALTRLLEALRVP"
     misc_feature    complement(19957..19971)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.41"
                     /tool="antismash"
     gene            19990..20847
                     /locus_tag="BGV78_RS29725"
     CDS             19990..20847
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445567.1"
                     /locus_tag="BGV78_RS29725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_071339541.1"
                     /transl_table=11
                     /translation="METDEGPASTSTAGTAARVRAVIADAGVSQREFARRVVMDPSKLS
                     RALSGTRRFTVAELARIADEGRVDADWLLGTRPRERETAPAVHVEGGRPLQIVRETVRL
                     IAEHGFHAVRVADIARACATSSAAIHYHFPGRAELLEAAVRWCMDEDTARRAAHLAEAD
                     DAAAELRQLIALQTPRTAQQRRQWAVWLDLWAEAARSTAVGRLHSEYYRQWRETVTDVL
                     RRGAGQGVFRAGIDPHAAALTLTALIDGLATHVLSVSGPESATAADAMHRTLTTHITHT
                     ILAP"
     gene            20918..21811
                     /locus_tag="BGV78_RS29730"
     CDS             20918..21811
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946448.1"
                     /locus_tag="BGV78_RS29730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-keto-5-aminohexanoate cleavage protein"
                     /protein_id="WP_018469560.1"
                     /transl_table=11
                     /translation="MPMTENVIITCALTGAGDTVRKSPHVPVTPEQIARNAVEAAAAGA
                     AVVHIHVRDPETGDPSRDPKLYREVVERIKETGTDVVINLTAGMGGDLVIDPDDPLTHL
                     PGTDLVGGLERLPHVEDLLPDICTLDCGSLNFGDGSNLYVSTPDMLRAGARRIQELGVR
                     PELEIFDTGQLWFAKQLLAEGLLDAPTVFQLCMGVPWGAPADPGVLQSMVNMLPDGARW
                     ASFALGRMQMPWVAQSILLGGHVRVGLEDNLYLGKGNKATNAQLVERAVTLTESIGARV
                     ATPDEARATLGLKKRK"
     gene            21838..22869
                     /locus_tag="BGV78_RS29735"
     CDS             21838..22869
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /GO_process="GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1095: 3-hydroxybutyryl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414044.1"
                     /locus_tag="BGV78_RS29735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-hydroxyacyl-CoA dehydrogenase NAD-binding
                     domain-containing protein"
                     /protein_id="WP_071339542.1"
                     /transl_table=11
                     /translation="MTSPEKTSPDPTSPKATTWKATLTETTSPENIRRVACVGAGVIGG
                     GWVAHFLARGYDVTAWDPAPDTAQKLRRLVDAAWPALTSLGLAEGASPDRLTVTETLEQ
                     AVADAEFVQESAPEKLDLKRDLLTRLDAATPPGVVIASSTSGYPMTDMQTTAADPSRLV
                     VGHPFNPPYLIPLVEVVGGEHTDPAAVAWATRFYEAAGKSVITMNNEVPGFIANRLQEA
                     LWREALHMVANGEATVRDIDLSITEGPGLRWAVMGPMLTFALAGGEGGMAHMLDHFGPS
                     LKSPWTRLEAPELDRELYDAVVAGCDEAADGRSIADLVAERDKGVIDVLRATGRLGREG
                     EAR"
     gene            22866..23345
                     /locus_tag="BGV78_RS29740"
     CDS             22866..23345
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414045.1"
                     /locus_tag="BGV78_RS29740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thioesterase family protein"
                     /protein_id="WP_071339543.1"
                     /sec_met_domain="4HBT_2 (E-value: 3.6e-30, bitscore: 95.3,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKLPPFRSTVRPEWIDYNGHMSEAYYSLVFGHATDALMAETGLG
                     PAYRESTRCSLYTVESHIRFLQDVPEAAHLAIRTRVLGVAARKAHFTHEMYVVSALGAE
                     PPADALPVATTELLAVHVDQQAGRAAAFPDTVRHRFAELTEPPPAWAGRSIASVA"
     gene            23535..24575
                     /locus_tag="BGV78_RS29745"
     CDS             23535..24575
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018896353.1"
                     /locus_tag="BGV78_RS29745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="vWA domain-containing protein"
                     /protein_id="WP_071339544.1"
                     /transl_table=11
                     /translation="MSGNQNYINHVALVLDASSSMSRLSGKVIEVADQQIAYLARRSRE
                     LDQETRVTVYVFANKVECVIYDKDVLRMPSLKQLYRVGGMTALLAATLTSQRELAQTAQ
                     LYGDHSFLTFVLTDGQENASHRCPGAPSQKPKELVAAVAQMIETQQDNWTLAVLVPDQM
                     GKREAMQYGFPKDNIAIWDATSTQGLQEAGQVIQEATEKFMVGRTQGIRGSRAVFSMSA
                     EVVNKDTIKAAGLTPLNPSDYHLIPVTCDAAIRDWIVSSGHTYRTGGAFYQLSKSEKIQ
                     PRKQIAVLEKKTDRIYTGPQARALLGLPDIEVRIKPDHNDDFTIFVQSTSVNRKLAPNT
                     RVLFMP"
     misc_feature    complement(25006..25023)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.07"
                     /tool="antismash"
     gene            25470..26387
                     /locus_tag="BGV78_RS29750"
     CDS             25470..26387
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008411005.1"
                     /locus_tag="BGV78_RS29750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydrolipoamide S-succinyltransferase"
                     /protein_id="WP_256254004.1"
                     /transl_table=11
                     /translation="MAVAVAEVGGDVDAARAVLIKRAVPDVMALFAASRVGGRYEHSEF
                     PPTAGILQKRRQKGADEIWEGRPKWRAADLHRAAHAGHITVDVTVLDMNAAYLAALKTW
                     LPIGKLTHSQGDQHDPKRSGVHLVDPGEWTTPDLPSPLGSRQEPGPLWITEPTLRALIR
                     CAGMDLCTPPRILESWTSGASEGLLEKMRRGLVTVRDEAIADNDEVTTEYVKSMYSKFV
                     STIGESAANREIRRPDWMHIIRSQAFVNLWLKAYKAHKAGLTVVQMSGTDELHVSGNWQ
                     EIFPEGRGLSQVKAKNTYTLGGNE"
     gene            26384..26968
                     /locus_tag="BGV78_RS29755"
     CDS             26384..26968
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018468582.1"
                     /locus_tag="BGV78_RS29755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_071339546.1"
                     /transl_table=11
                     /translation="MSGASDLWGEFGKHHAQGQKGAQALGQEIERIARQGGITSPVTTT
                     RGLRARLRYLDSPAGRRALAEHGVSSRLLRAWADGRTPSRAKLAAVDAAYWGRRRENLV
                     RSGALKRLLDNEGRGRRIEIYPVDQSAVPEKRKRVISQRTVTARYIWDDAVGAWASGDL
                     NTLDEIWDDVISDLDSDYAAYAYVESIGISA"
     misc_feature    complement(27153..27168)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.49"
                     /tool="antismash"
     misc_feature    complement(27210..27219)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.29"
                     /tool="antismash"
     misc_feature    complement(27242..27257)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.86"
                     /tool="antismash"
     misc_feature    complement(27323..27341)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.28"
                     /tool="antismash"
ORIGIN
        1 aaggtgttgt tggcgatgga gcatggggtg gttccgggtt cgttgcatgt gcggcggccg
       61 aacgatcaca tccggttcga ggattcgccg ttctttctgg tggatcgccc gtgggtgtgg
      121 gggcgtgagg ggggtccgcg gcgtggtgcg gtgagtgcgt tcgggatggg tggggtgaac
      181 gcgcatgtga tcgtggagga gccgccacgg gtggagcgtg gcgcggtggt ggtccaggac
      241 agtcacctgg tgcgcgtgac gggagcggac gagcgggcgg tacgggaact cgccgccgcc
      301 tacgccgacc gcttcgccac ctcccggggc ccgtgggaca ccgcggacct gtgccacacc
      361 gccaacgtcg gccgctcgcc gcaggagtac gtgaccgccg tccacggtcg cgacgccgcc
      421 gaactggccg agaacctgcg ggccgtcgcc gccggacgcc tcccggtcgg cgtcgcaggc
      481 tccggcaccc gtgacccgga cccggcgccg accggccacg ccgccctggc cgagctggtg
      541 cggacggggt acaccggggt cgactggccc gcgctctccg tccccggcgc gcgcaccacc
      601 gacctgccga cctacccgtt cgcgccgggc cggcactggc acatgcacac cgaggtcacc
      661 gccccggccg aggacacgcc tccggaggcg taccgggcca cctggcgcga agaagcactg
      721 cctcaggagg cccaggccgc ccccggcact gtccgcctcg tcgtcaccga ccccgctctc
      781 cacgaggcgc tcaccgcgga actgcgtctg tacggcgctc acgtggccgg gaccgaggcc
      841 gaggcggaca ccgtcctgat ggtggacgcc accccgcccg gccgggagcc cgacctcagc
      901 accttctggg cacgtgtcgc ggatatgctg aaagcgctgc ccccgcacgg caggctgctc
      961 tgggccgcct gccacggcgc cgccctgcgg cccggggagc acgcgagcct gcgccccggc
     1021 acggcggccc aggccatggc cgtcgcggcc gcctgcgccg agagccgcat cgcccacgcg
     1081 gtcgtccacc tggacccgtc ggaaccggcc gaagcccggg cccgggtgct cgccgcagag
     1141 tacgcggcgc tgcgccaggg cggtgaaagc accgccgccg cccaccgggc gggcgtccgg
     1201 tacgtccccg acacgtcccc cgtgcggccc ggccgcgcct acgaggtccg gcccgacggc
     1261 tactacctgg tgaccggtgg cctgggagcg atcggccggc gcctcgtcga gcggctgatc
     1321 gaccggggcg cacggcacat cggcatcgtc ggccgctccg ccctcgaccc cggccggtcc
     1381 cagacgcttc gcgccctcgc cacgcgggcc gaggtggtct accggtcgtg cgacgtggcc
     1441 gacgccccgg cgctcaccgc cgtcgtcggc gaactggacg cgaggtgggg ccggttgcgc
     1501 ggcgtcgtgc actgctccgg cggagtcaac gccttcggcg cgatgcgccg ccgcccctgg
     1561 gccgacgccg cccgcgtcgt caccccgaag acggacggct cgctccacgc cgtccggctg
     1621 gcccaggacc ggggcgccga cttcgcggtg ctgacgtcct ccctcgccgg aacgcacgcg
     1681 gacgccggac gcggcctggt cgactacagc ctcgccaacg cctaccaact ggcgctggcc
     1741 gaacgggagc acgggcccgg caccgccgtc accgcccacg cctggcccaa ctggaccggc
     1801 gtcggcatgg ccgccgacgc cgccttcgcc gccgcccact ccctcgacgc caccgaggcg
     1861 gaagccgcct tcttcggcca tctgctcacc ggcggcgccg tcgtcctccc gggacacgcc
     1921 cccgcggccc cgcccgcctc cccggccgac acccccgaaa cccgggaacc cgggccgggt
     1981 acccgcacgg tcatccccgc cccggccacc ggccgcgacc gcaccgcact gcgcgcccac
     2041 gtacgggacg ccttcctgca cgtgctgggc gacgatccgg gcgaccgccc tctgcgcggc
     2101 ctcgggctcg actcgctggt catcgcggag ctcgccaccg ccctggaaca gcgggcgggc
     2161 cgcacggtcg acccctcgct gctgatgcgc gcccgcaccg ccgacgagct cgccgccgaa
     2221 ctggccgcca ccgccgccgg accgccggag gcgggcgcgg ggccggccgt tccggcggac
     2281 gcgacgggcg ccaccgcgct cagcctcctg ctgaggcccc tgctcaccga cggcggagac
     2341 ggggtgacgc cgtgaccccg caccccaccg cagacccgac cgggaggacc gccgtgaacg
     2401 aagaggaccg ccggatcgcc gtcatcggcc tggcggcacg gctccccggc gccgaggacg
     2461 ccgccgacct gacggagatg ctgcggcacg acaccgtcga ggtcgacgag gtcccggcca
     2521 gccgctggcg ccgcgacctc cacctcgggg acggccccca ccagggctcc caccaccggg
     2581 gtgccttcct cctcgacccg ttctccttcg accacacggc gttcggcctc accgccgacc
     2641 aggcccgcag cctcgacccg caacagcgga ccatgctgga ggtcggcgcg cgggcgctgg
     2701 aggactccgg ctacctccgg acccggcgca ggctcaacgc gggcgtgttc gtcggcgccc
     2761 gcatgaacgc ctacggcttc gaccagggac gcggccttgg cggagcaccg cagaccgcag
     2821 caggcccggc cgccctgtgg ggcagatcgc agaacttcat ggcggcctgg ctctcggacc
     2881 gcttcgacct gtcgggcccc agcctcgtcg tcgacacggc ctgctcctcg tccctgaccg
     2941 ccgtctggct cgcctgccag agcctgagcg cgggcgcctg cgacctggcc gtggtcggcg
     3001 gggtcgacct gctcatcgac cccctgacgt tcgtcctgct ctcccgcaac ggcgccctct
     3061 caccggacgg cctctgccgg accttcgaca gcagggccga cggttacgtg cccggagaag
     3121 gcgccgtcgc cctggtactg aagcccctgc gcgccgccct cgccgaccgc gacctggtcc
     3181 tcggcgcgat cgacgcggcg gccgtcaaca acgacggcgc caccatgggc gtcaccaccc
     3241 cgagcctgga cgcccaggtg gaactcctcg gcaaggtcta cgagacgatc gaccccgcca
     3301 ccgtccagta cgtcgaggcg cacggcaccg gcaccgccat cggcgacccg atcgaggcgc
     3361 gcgccctcac cgaggtgttc ggccgtgccg gggtcccgcg cgggtccgtc gccctcggct
     3421 ccctcaagcg gcgcatcggc cacctccact cggcctccgg actcgccggg ctcgccaaga
     3481 tcctcgtcct gctccgcgaa ggactcgtcc ccgcgctcgg cgtcgaacgg cccaaccccc
     3541 gcctcgacct ggcgaacagc cccttccacc tgccggccga gccgggcccc tggccctcgg
     3601 tgccggtccg ccgggcggcg gtgagcggct tcggcttcgg cggcaccaac gcgcacgtcg
     3661 tcgcccaggc ggtggccgta cccgaagcgc agatccccgc cggtcccgtc accccgacgg
     3721 tccacgtcct gccgctgtcg gccaccaccg ctcacgggct ccgcgaactg gcggcccagt
     3781 ggctccagtt cctcccctcc gccgccgagg acctgcacca cgtgtgcgcc accgcccggc
     3841 tggcccggcc ccaccacggc gaacggctcg cggtctgcgg cacggacgcc gccgcactgg
     3901 cccaggccct gcgcacctgg ctgctgcggc ccggcgggac cgaggagccg ccccggacca
     3961 ccgtgccggt ccgcccggag gccgctgcca caccgcccgc ctggcttacg gccctgcgcg
     4021 gcgccacccc cgccgtcgac gaggtcctcg gcctcttcga gacggcgacc ggccgccggc
     4081 tggagacgtt ctcgggagag ctgctgcggc tcagcaccgc ggtcgccctc accgtggccc
     4141 tgcgtgcggc cgggctcccg gaggacgccg tcgagcttcc cgccgggtgg acggcggtca
     4201 ccgacttcgc ctggggacgc gtcccgctgg agcaggccct cgccgacgtg ctccggcacg
     4261 acggcgagcc ctcgcgcacc gccgaggacg cggcgcgacg ggacgacggc gagctctgcg
     4321 cgcgcctggc cgccgtccgc gacgcgccag gggcggccgc cgtgaccgcc gccgtcaccg
     4381 ccgaactctt cgccgccggt cacgccatcg actggatggc cctccaggtc ggccgcccct
     4441 ggcacaagcg gctgctgccc gtcgcccagc ccgacggacc cgccctggac ctccccgagc
     4501 cgctgcgctc cgccgaaccc gggacaccca cggcggacgc ccccgaggag gccgacgccg
     4561 ggggacacgc ctttgcccgg gtcttcgggc ccggggagac accgatcgcc cagcacgccg
     4621 tgtaccgcac ggtgatgctc ccgggcgtcg cctggttcga cttcctgcgc gaaggggccg
     4681 ccctgcgcgg tgtgcccttc cacggcgtcg ccgacgtcct cttccaccgc cccctcatcc
     4741 ccgccggggc ctctcgcgtg gtctgccggg tggcgggcga cggcgcgttc accgtcgagg
     4801 acgccgagag ccgcgaagcc ttcgtcaccg gccggtacct caccgggcgt accgccgaac
     4861 cgtctcccga accggtcgcc tccctcctgg agtcctgcgc ggagatccac gcgggctccg
     4921 ggctgtaccg ctggctgcgc cggatcggct accaccacgg ccgctactac cggaacatct
     4981 cctgggtcgc gggcctcccc gacggcggca cactcgcccg cgtcgaaggc gcccgccagc
     5041 agccgctcaa tccggcgggc accgcactct tccccgggct gctcgacagc gtcaccatcg
     5101 ccgcgatcaa ccccgacaac ccggtgttcg gtgcgggcga cgcggccgcc ttcatcccgc
     5161 tctcggccgg ccgcgtcgag gtgtacggcc cgctggagga ggcggcctac gtccggaccc
     5221 gtaccgcctt ctggaacgac gaggcgtgcc gcgtcaccca gaccgtgacc gacgcgaccg
     5281 gccggccctt gctgaccttc accgacatgg cctccaagcg cgtgccggcg gcggccttcg
     5341 gcgacgcgcc ggaggcactt ccctctgctc cctccgctcc ctccgccccg gcaccggctc
     5401 cctctccgcg ccccgctccg gaacgggccg cgccccccac ccagccggcc gcccccacca
     5461 gtccggcgag tgcccccgca cggctcctca cctggttcct ggccctgacc gggaccacgg
     5521 ccgaggacgc cgacaccgag ttcctgtcgg ccggattcga ctccgtcggc ctggtctcgc
     5581 tgagcgagcg cctctccgac gaacacggcc tcaccctcta ccccacggtg ttcttcgagt
     5641 accccacccc gcgccgcttc gccgagttcc tgctgaccga ggcaccggcg ttcgcggact
     5701 cgcccgccgt caccggcgcc ggcgggacgc aggactccac ggcgcgcccg ccggaacccc
     5761 ccgcgcccgc cccacctcca cccccgccgc ctcctgccgt gccgcccgca gccccgccga
     5821 accccgccgc gagcgagccg cccgcccggc cccggcgcac cccggcccgc cccaccccgc
     5881 aggagccgtc ccacacccgg gacatcgccg tcgtgggcgc ggccgtccgg ctgccctcgg
     5941 cccgcggcct cgccgagttc acggacctcc tcgacgaggg ccgggacacc gtccgcggcc
     6001 tgccgcaaga acgcggcggc cagggcgaag gagccggccc ctacgcctcg ttcctcgacc
     6061 gcgtggacga gttcgacccc gcccccttcc gcatctcccc ccgcgaggcc ccgctgatcg
     6121 acccgcaggc ccggatcgtc tacgagacgg tctgggaggc gctggaggac ggcggccgta
     6181 ccggacggcg cgccgaggac agcaccaccg gcctgtggat cgcctacagc cacgaccact
     6241 accacgagga gcgcgtccgc cacggcgccc acgaggggcg cggtctcggc ctggaggcga
     6301 tgatcgccaa ccggctgtcc tacctgatgg actggcacgg acccagcgcc ctcgtcaaca
     6361 ccctctgctc ctcctcgctg gtggcactgc acaccgccgt ccagcacctg cggtccgggg
     6421 acatcgacac cgccgtgatc ggcgccgtgc acgccgccct gagccccgag tacttccgct
     6481 ccatgggcga cctcatggcc ctctcgcccc gccaccggtg ccgggccttc gacgacacgg
     6541 ccgacggctt cgtgcccggc gagggagccg tcgccgtggt gctgcggcgg tacaccgacg
     6601 ccgaacggga cggcgaccgg gtccgcggcc tggtcaaggg cgccgccgtc aaccacggtg
     6661 gccggacgac ccgctactcc gcgccgagcc ccaaggcaca acgggacgtc gtcgccgcgg
     6721 ccctgaacga cgccgccgtc ccgcccgaga ccatcgacct ggtcgaggcc cacggcacgg
     6781 gcacccgcct cggcgacccc atcgagatcg acggactgac ccgggcctgg cgcgcgcaca
     6841 ccgaccgctc ccagttctgc gcgatcggct cactgaagtc caacatcggc cacctcgaac
     6901 cggcggccgg cctcgcgggc ctcgtcaaga tcctcctggc gatggagagc gaacgcatcc
     6961 ccgccaccct gcacgtgacc cgccccaacg accacatccg cttcgagggc acccccttcc
     7021 acctcgccga ccgcgcccgg ccctggccgc gcggcgagcg cccccgccgc gccgccctca
     7081 gcgctttcgg catgggcggc gtcaacgccc acgtgatcgt cgaggaacca cccccggccg
     7141 cggaccgtca ccccctcgcc caggacagcc acctcctccg ggccggcgcc gccgacgagc
     7201 agaccctgcg caccctggcc ggtgcctacg ccgaccagct cgcccgcacc cccgccgagg
     7261 ggatcggcga cttcacccgc accgccaaca ccgcccgcgc gacccaccgc caccgggtcg
     7321 tcgtccacgg caccaccggc gccgaactcg ccgaacggct cgcggccgtc gccgccggca
     7381 ccacgcccac cgtccggcac accgaccgca ccaccaccgc gttcctcttc accggccagg
     7441 gctcgcagta cgccggcatg ggccgcggcc tgctcgccac cgaaccgcac ttccgcgacg
     7501 cgctccacga gtgcgccgac ctcctcgccc cgcacaccga cgtcccgctg ctcgacctcc
     7561 tccacggcga cgcccggcac ctcctggacc agacccggta cgcgcagatc ggcatcgtca
     7621 gcatccaggt cgccctcgtg cggtacctgg cggcagccga cgtacggccc gacacggtgg
     7681 ccggacacag cctcggcgaa ctcaccgccg cctggaccgc cggcgtcctc accctgcccg
     7741 acctgctgcg gctcaccgcc gaacgcggca ggctcatgca ggccgccccc gccaccggcg
     7801 ccatggccgc cgcccacacc gacgcccgca ccctggcgga caccctggag gcgtaccccg
     7861 gcatcgagat cgccgcctac aacgcgccgc gcctccagac cgtcaccggg cccgccgaag
     7921 ccctcgaacg gctacgggcg cacgccgcct tcaccgtccg gccgctgacg gtcagccacg
     7981 ccttccactc ggctctcatg gacggcgccg tcggcccgtt ccgggaggcc gtggccaaaa
     8041 cccccctggc accgcccacg ctccccttcg ccagcaccct caccgggagc tggcacaccc
     8101 ccgcgaccgc caccgatccc gcccactggg cccgcgccgt ccgcgagccg gtccgcttcg
     8161 ccgaggccgt caccacgctc cacggcaccg gcccgcacac cgtgtgggag atcgggccgc
     8221 acccgcacct gatcccgctc gccagggcca cgctcgccgc acccggcgcc accggcgccg
     8281 gcccggcctg gatcgccacc ctccgccgcg accacgccga ccaggtccaa ctccacgccg
     8341 ccctcgccgc ccaccacgac cacaccggcg ccgacctcga ctgggccgcc ctgcacgacg
     8401 gcaaggacca gcgcgtgacc accctgccca cctatccgtt ccaccgacgg cgcttctggc
     8461 tcccggccga ggaccgggac cacgccacca ccagcacatc cgacgacacg agaaggcccg
     8521 agcaccatgg ctagcgagta cggactgaag cgacacttca acggcgaggc cgcccgcctc
     8581 atcggcggga agatccgcgc cctccacccc gagttcgacg tcgaggcgta cgccggggag
     8641 gtcgagcagc gcatccccgg caaggaactc aaggaccgcg tcctggtcct ggccgaggga
     8701 ctgcgtaccc ggctgcccgg cggctacccg gacgccctgc ccctcctcct cggcaccctg
     8761 ggcgacgaac tggccgaggg cgagggcatg ttcaacacca gctggtacct gatgccggtc
     8821 gccaggttcg tcgaggagta cggcctcgac cacccggagc tgtccctcga cgccatcgag
     8881 gcgatcaccc gctgccacac cggcgagtac gcgatccggc cctacgtcga gcagcaccac
     8941 ccccggacga tgaagcgcgt cgccgagtgg gcgctcagcc ccagccacaa cgtgcgccgc
     9001 ctggcgagcg agggcgtccg cccccgcctg ccctgggccc gcaccctgga catcttcgtc
     9061 caggacccgg cccccgtcct ggcgatcctc gaaccgctgc gcagcgaccc ctcggagtac
     9121 gtccgcaagt ccgtcgccaa caacctcaac gacatcgcca aggaccaccc ggagaccgcc
     9181 ctcgccaccg ccctgcgctg gctggaggag agccccaccc ccgagaccga atggaccgtc
     9241 aaacacggcc tgcgcactct ggtcaagaag gggaaccagc aggccctggc actgctgggc
     9301 gccaccgggg gagagcacgt ccaggtggac cggctgtccc tcaccccgaa ggcggtcacc
     9361 gtcggcgaca ccgtcgtcat cgacgtggac cttgccaaca ccgacgaccg cccccacagc
     9421 gtcaccgtcg actacgtcgt ccaccacgta cgcaagaacg gccgcagcat ccccaaggtg
     9481 ttcaagctga cgacgctcga actcgccgcg ggggaacggc gcagcctgcg caagtcccac
     9541 cccctcaggg aggtacagac ccgcaagtac taccccggcg agcacgccgt cgacatccag
     9601 gtcaacggcc tggtcaaggc caccgagaga ttcgggctgc gcacatgagc ggagcccggg
     9661 tccacctcac cgccgccgat ccgctggtcg ccgaccaccg gatcggcggc accccggtcg
     9721 tcgcggccgc ggcgcagatc gacctcctgc tccgcgcctg cgacgccgcc cggccggacc
     9781 gggtccgcac gctggagcac gtcgccttcc gggcgccgct gcgggtgacc ggacccgggg
     9841 ccgtactgga cgtcaccacc gacgacgggc ggtgcgcact gcgctgcgac ggcaccgagt
     9901 acgccaccgc ccgccaccgg gacgcctcgc tgccaccgcc ccgctacctc gacgtggccg
     9961 gactgggcgc ggggtgcgcg gaaccggtgc cgctcgccgg gctggacgcg tggcggcggg
    10021 ccagcggcat cacctacggc cccgcttacc gggcgatacg ttccgcgcgc cgggggcccg
    10081 gccggatact ggccgtggtg cgcgccggcg acgacaccag ctgcgcgccg gcgttcgtgc
    10141 cgccgccgct gctcgacagc gtcttccagg cactcggcct gctcgacgcc ggagccgccg
    10201 gggcctgcct gccctggtac gtcggccgga tcaccgctcg ccgccgcatc acgggaacgg
    10261 tgctcgccct cgtcgagcgg gaggcgggcg aggaggccgc gaacggggcc gtccgcggcc
    10321 gggccaccgt ctgcaaccag cagggagaag tcctcctcga actcgaccgc atcaccctga
    10381 agtccgccgc gccgcccgcc cccgacccgc tgccctcgcc caccacccac ctcatcgaga
    10441 cggtcggctg gcgccggagc gagacggccg gcccgccacc ggacggcgag ggcgccgtcc
    10501 tgctcgtcgc cgccgacgac cggacccccg ccgggctccg gccagacatc cgcctgacgc
    10561 ccggcgaact gacgccggaa cgactcgacg aggccctcgc cccacacacc ctccacgagg
    10621 tggtctacgt cgcccccgag ggcctgtccg gtgccgggcc cgcgaccgag gcgctccagc
    10681 aggtcttcgc cctcgtacgg catttggcgg cccgcccgcc gatgccccgg ctgctgatcg
    10741 tcaccaccgg cgcccaccag gtcagcggcg acgaggcacc cgaccccttc atgaccgccc
    10801 tgtggggcct gggccgcacc ctgcgcgtgg agcacccccg caccaccgtg cgcctcgccg
    10861 acctggaacc cggcaccacc gccccgctcc cggccatccc gtacgggcag gacgagctcg
    10921 ccctgcggca cggcacctgg cacaccccca ccacggaacc ccagcagccc ctcccggtca
    10981 ccccgccccg cctgagcggc ggccgcttcc tgatcaccgg cggcatgggc gccatcggcc
    11041 tgcgggtcgc cgaactcctc gccgacgcgg gctgcgccca cctgaccctg gtcggccgga
    11101 ccgtccccga cgaaggcgag cgacgccacc ggctcgaccg gctcggtacc cgctgcgccc
    11161 tcgacatcgt cgccgccgac gtacgcgacc tgcccgctct cctcgccgac gccccgcgct
    11221 tcgacggcgt cttccacacc gccggggtgc tccgcgacgg cctggcccgc ggcctgacac
    11281 cgcagcggat cgccgaggtg ctcggcccca aggcaggcgg cgcgcacgcg ctcgccgaac
    11341 tgaccgccgc ccacgaaccg cccggcttcg tcgccctctt ctcctccgtc gccgcagtac
    11401 gcgccaacct cggccagagc gcctacgccg ccgccaacgc ctacctggac ggcttcgcgg
    11461 cccgccagcg cgccgccggc cgcccctggt acagcctcgg ctggggactg tggacggtcg
    11521 gcatgggcga ggacgtcgcc ccccgggccg ccacccacgg cgtgcccgcc ctcaccccgg
    11581 acgacggcgc cgccctgctg cgtaccgtcc tcggccgccc gcccgcccac tacgtcctgt
    11641 ccgccaccgc gcaagcgaag ggtgaaccca tgaccgccgc cgtcgaaccg gaaaccgggc
    11701 tctggcccca cctggctgcc gcactgcgga aaattctcca cgtcaccgag gtctccccgg
    11761 acgacgacct gctggagatg ggcctcgact cgatgatggc ggtcgaactc gccgccgctc
    11821 tctccggcag tggcctcgac atcgacccga tggtcttctt cgagcacagc cgcgtcagcc
    11881 tcctcctcgc cagcctggag aaactgcccc gcagcggcca ggagcccgaa gccaccgtgc
    11941 cggcccccgc tcccgctccc gccgtggctc ccgtcgcccc cgcacccccg ccgccgcccg
    12001 ccccggaacc ccaccggccg gcccccgcac ccgccggcac cttcgtcccc gactgggacc
    12061 gctaccgcac cccggccccc ggccccgcca ggcccgctcc cgccggccga gcgccgcgcc
    12121 cgccccggcc tgccgacgac cgggccgccg cccgcgtccc ccgccggacg ctgcccggcc
    12181 ggctccgcaa cgcctccggc ggcagcttcc tcgaccggcg catcgacgcg ctctccgagg
    12241 aggaccgcct gatcgtcgcc cgggacgagt acttctacga gcccgtcatc gagcaggccg
    12301 agggcgcgcg catcaagttc gacggccgct ggttcctcaa cttcgcctcg tacagctacc
    12361 tcggcctgat cgggcacgac tacatcgacc agcgggccct ggacgcagtg gaacggcacg
    12421 gcaccggcgc ccacggcgta cggctgctcg ccggcaccct ccacctccac cgggaactgg
    12481 aactggccct cgcccggttc ctcggggcgg aggacgccat cgtctactcc agcgggtaca
    12541 tggccaacgt ggccaccgtg ggcgccctcg tcggccccgg cgacgtcatc atcggcgacg
    12601 tctacaacca cgccagcatc ctcgacgggt accggctctc cggcgccgac gtcatcacct
    12661 acgcgcacaa cgacctcgcc gacctggaac gggccctcaa gaaggccggg gacgccggcc
    12721 ggctggtggt gaccgacgcc gtcttcagca tggacggtga cgtggccgac ctgccgggca
    12781 tcgtcgacct ctgcgagcgc tacgacgccc cgctcatggt cgacgaggcg cacagcctcg
    12841 gcgtcctcgg tgacaccggg cgcggcatca ccgagcactt cggcctcgac ccggaccgcg
    12901 tcgacgtcaa gatgggcacg ctctccaaga ccgtgcccag cgcgggcggt tacgtcgccg
    12961 gctcccgtga cctggtcttc gccctgaaga acaacgcgcg gggctggatg ttctcggccg
    13021 ccgccacccc cgcccagatc gccgcggcca aggcggcgat cgaggtgatc gaggccgctc
    13081 ccgaacgcgt ccgcgaactg cgggccagaa ccacgcggta ccgcgagcgg ctgcgcgccc
    13141 tcggcttcga cacgctgacc ggcgaaaccc cggtggtccc ggtcatctgc ggcagcgccg
    13201 agcaggcggg cgccatggcc cggctctgcc agctcgacgg gctgttcgtg cagcccatcg
    13261 tctacccggc cgtgccgcgg accctgcccc gcctgcgcac catcgtcaac ctcgaccact
    13321 ccgaggccga cctcgacacg gcggtcgacg tgctggagaa ggccggccgc gcctgcggcc
    13381 ttcttccctg accaagcgac accggactct cctcaggaca cggaacacag gattcaggac
    13441 acccaggggg taggacatga ccgacatcga tgccgcggcg ttcttcgccg cagtgctgaa
    13501 gaccatcgcc tcgacccgca acaacggcgc cggccccgag gagcacacgc agggcgtggt
    13561 ggagccggcc ggccgcatcc gcgccgtcga gcaggaggcc gccgaccggc gcctcaccac
    13621 cggcgaggcc ggagaggtcc tggacctcct ggagaccacc ttccggacca agcgcacccc
    13681 tgacgaggag cgggagtact acctccagta catcgagaag gtctccgggg tcagccgcgc
    13741 ctcgctggga gtgtccgccc cgtgaacgcc ccccgcgccg cctggtacag ccacgagctg
    13801 tgccactggc acgatcccgg ggccggatcg ggctacctgc ccgtcggccc cggcatcgag
    13861 ccactgcggc agttcgccgt cgatcccgac ctgcggcgcg ccgagggcct ggtccgggcc
    13921 tccggggtga tggaccactt cacggccgtg accccgctgc ccgccaccga cgaggagctc
    13981 ctgcgggtgc acgtgcccga gcacctcgaa cgcgtcgagg cggcctccgc ggcgggcgcc
    14041 ggcgacgcgg gcgtgtacgc ccacgtcaac taccacagcg cgcacgccgc acggctggcc
    14101 gccggcgcgt gcgcgcaggc cgccaccgcc gtcgtggagg ggcgcttcga gcgggcgtac
    14161 tgcctggtgc gaccacccgg ccaccacgcc gaaccggacc gcgccatggc cctctgcctc
    14221 tacaacaacc tcgcggtcgc cgcccgcacc gcccagcgcc acggcgtgcg ccgggtactg
    14281 gtcctggact gggacgtcca ccacggcaac ggcctccagc gggtcttcta cgacgacccg
    14341 gacgtcctgt acatctccct ccaccaggac ggactcttcc cggccgcctc cggccgcgtg
    14401 ctggagaccg gcaccgggaa gggcaccggc cgcaccctca acgtgccgct gccggccggc
    14461 agcggacacg gggcgtacct ggccgcgctc gaccagatcg tcgaacccgc ggcccgcgcc
    14521 ttccggcccg agctgatcct ggtcgcggcc ggcgtcgacg ccggcgccca cgacccgatg
    14581 ggccggatga tgtgcaccag ccgcaccttc cacgccctgt cctcggccct gtgccgcctg
    14641 gcggacgagc tggcgggcgg caggatcgtc ttcgcccacg agggcggcta ctcggcctgg
    14701 taccagccga cgctggtgct cgcgaccgcc gccgccatcg ccgggctccc cgccccgcac
    14761 gacccgttcc tgcacgcgct ggagcacctg cccggccagc gcctgcaacc ccaccagagc
    14821 cgggtcctca cccacctgcg cgaccaccac ccgctcctta ccggccaggg aacccccgtc
    14881 ggcgcggcac ccggaggggc cgatggatga ctggtggctg agagcgggcg ccggggcggg
    14941 cgcgaccggc gagcgggccc ggcgccgcgt ggtcgccctc ccgcacgccg gaggctggcc
    15001 ctccgcgttc cgcagctggt ggcaggtact gccgcccgac gccgaactgc tcgtcgccca
    15061 gttaccgggc cgcggggcgc gcctgggcga gccgcccctc acctccgtcg agccgctcgt
    15121 cgaggcactc agccgcgaac tcgcggaacg cgacccgctg ccctacacgg tggtcggcca
    15181 cagcttcggc agcgtcctcg gctacgaact gacccgcgcc atggaacaga agggcctcgc
    15241 ccccgacctg ctcgccgtct ccgcccgcca gccgccctgc ttcccgagcc tgccgccctt
    15301 cgcccacctc cgcagtgacg cccagttgct ggagcacctg acggagatcg gcgggatggc
    15361 cccgcagctc atgacccggc cggagctggt ccagcccgcc ctgcgcgcca tccgcgccga
    15421 cctggaggcg atggagcgcc accagcggcc cctcaccggg accggcgtgc cgatcctcgc
    15481 cctcggcgcc gtcgacgatc cggtcgtcgt cgccgagcgc cttcacctgt ggtccctgga
    15541 gacgaccggt ggcttccacc ggtccctgta caccggcggc cacttctacc tgtacgccca
    15601 cgccaacgcg gcggccatcg cccgccgcct gttggccgac cgccccggcc cgacggccgg
    15661 acaccctgcc ccaccgacgc cgggccgccc ggtccccgta ccggacggcg tcccggcgcc
    15721 atctccccga aaggaaacac cttgagcacc atcgccgaca tccccgccaa ggcagggccg
    15781 aaggagtggc tggggctggc cgtgctggcg ctgcccacgc tgctgctgtc gatcgacgtg
    15841 agcgtgttgc acctggccgt gccccacatc agcgaggcgc tgaacccctc ggcctcccag
    15901 atgctgtgga tcatcgacat ctacggcttc ctgatcgccg ggttcctggt cacgatgggc
    15961 accctcggtg accgcatcgg ccgccgcaag ctgctgctca tcggcgccgc cgccttcggc
    16021 ctcgcctccg tcgccgccgc ctacgccgac gacccggcgc tgctgatcgc ggcccgcgcc
    16081 ctgctgggcg tcgccggtgc cacgctgatg ccctccacgc tggccctgat cagcaacatg
    16141 ttcgccgacg cgcgccagcg cggcatggcc atcgccatct gggtcaccat gttctcggtc
    16201 ggcatcgcgc tcggcccggt ggtcggcggg gccatgctgg agtacttctg gtggggctcg
    16261 gtcttcctgc tcggcgtgcc catcatgggg ctcctgctgg tggcgggccc cgtcctgctg
    16321 cccgagtacc gcgacgagaa cgccggccgc ctcgacctga ccagcgctct gctctccctc
    16381 gtcgccatcc tgccggtgat ctacggactc aaggaactgg ccaaggacgg cctggccgtg
    16441 ctgccgctgc tgaccctcgt cgccggtgcg gccctcgcgg tggtcttcgt ccgccggcag
    16501 cgcaccctgg acagcccgct gatggacttc cgcctcttcc gcaacccgac cttccgcacc
    16561 gccctcgtga ccctgctgct cagcatgctg gtggcgggcg ggacctacct gctggtgacc
    16621 cagtacctgc aactggtcgg cgggctcacc ccgatgacgg cggggctgta cctgctgccg
    16681 gcggccttcg cgctgatcgt cacctccgtg gtctccccga tcgccgcgag caggttccgc
    16741 cccgcccacg tggtggccgc gggcctggtg gtctccgccc tcggccacgt catgctggcc
    16801 acggccgaca gcacgtcggg aatagcccag gtggtgaccg gcttcgcctt cgtctacggc
    16861 ggcggcggac cgctggtcgc cctcggcacc gacatcgtgg tcgggtccgc cccgcccgag
    16921 caggccgggt cggcctcggc ggtctcggag accagtacgg aactgggcat ggccctcggc
    16981 gtggccaccc tgggcagcct cggcgcggcc gtttaccgcg cgggcgtcga gcttcccccg
    17041 ggtgtggggg acggtgcggg cgacaccctc gccggcgcgc tcgacgcggc gaagagcctg
    17101 cccgccgagg tggcgtcggc gctcgccgac tccggccgcg ccgccttcac cgacggcatg
    17161 aacgccgtcg gcgccgtcgg gaccctgctc gccctgggct ccgccgtcat ggtggccatg
    17221 gtgatcaaga gcccgcccac cggcgccggc gaggagcccg ccaccgggga cgagccgctg
    17281 gtcaaggccg cggagtagcc gtcccccgag aacggagccg gggctccctt cgtcccccgc
    17341 gtgcggtggg ggagaaggga gccccggcgg ggtggcgcgg tctcaggagg ggtcctggta
    17401 cgcgtcggcg tactccgcgg acggctcgat cggcgagatg acgtcgacca gtacgccgtc
    17461 cggcgccgcc acgatgaagt gccgctgccc gaagtcctca ctccggagcg gcagctgggg
    17521 acgcaggccg gcgccgtcga cgagccgcgc gtactccgcg tcgacgtcgg ccacctcgaa
    17581 gttgagcagc accccctgga cgggctgccg gaacccctcg ggcaccgacg ggtgtcccgc
    17641 gtcgaccagt gccagttcct ggtggggcgg ctcggaccgc ctgaggctca cgtaccactc
    17701 gttctcgaag gtcgtctcga agccgaacag gttcttgtag aacgccgccg actcactcag
    17761 cttccgcgta cagagcaccg gatagaagct ggtcagggca gagggggcca tctcgctcac
    17821 cgttccgtgg aggggcgggg tccggctgtc ggcgacgccc gccgggttct tcatggcaac
    17881 gagaggagcg ccggggcgtt acgtcccgca actcggtcgg ccgtcacccg gaccatgttg
    17941 acataccggc ggtacgtcat taacttcggc aggcataccg tcggtacgtg agttgagggc
    18001 ggcgcccatg ctggccagct tctgtcccgt gatccgcaca tcccgcatcg aggagtcccg
    18061 cgccttctac accggcctgt tcggcttcaa ggtcacttac gagacaccgt ggtacgtgga
    18121 tctggcccgc cccgccctgc cgccccgcga actcagcctg atcgacctcg gccacccggc
    18181 cgtgcccgag gcccagcgat tacccgtacg ggccgtacgc atcgtcctgg agtcggaagc
    18241 cggggaggcc gaactccagc acgccctgag ccgcgccgga ttcgacgcgc ggcgcgtgtt
    18301 ccggcccccg ggccgggcgc ccggagccct caccctcatg gaccccagcg gtgtgcgggt
    18361 ccatgtcgtc gcacccgcct gaccaccggt ccgctcggcg accacggatg ccccagggga
    18421 gacgtgccat gcccgcaaga atcgatcccg acacggcggc cgcggtgatg cgcgcggccg
    18481 gactcgaacc catggagccc taccccgggg cgaacgtggc ctggaactgc cgctgcctca
    18541 agggcgccca cggggtggca cccaccttca cctcggtccg caccggcacg agttcgggat
    18601 gccggcactg cggcaggacc gccgcggggg agcggcgccg cgccgcgggc caggcccgag
    18661 cggaggccga catgagagcg gcgggcttcg aacccctcga cccctacccc ggcgcccgga
    18721 tgcgatggcg ctgcctgcac accgcctgcg gccgcgtggt gcacccccgg ctcttccaga
    18781 tccgtaccgg cggcggaggc tgcctggcct gcgcgggccg ggcacctgtc gagcccacgg
    18841 ccgccgaggc ggagatgcgc gccatcggga tggaaccgct cgaacccttc cccggccgcg
    18901 tccgcgaccc ctggagctgc cgctgcaccc ggtgcggcca cgtcggcaca ccgaccctca
    18961 acaacatccg ccgcggccag ggagggtgct acccgtgcgc ccaccgcggc cggtgaccgc
    19021 accgctcacg gcacgcgcaa ggcctccagc aggcgggtga gcgccgccgt cgcgtcggcc
    19081 agatcggccg ggtcggacga ggcggccagc cacagcgccg cctcgttcat cgcgcccgac
    19141 agcagatggg tgagcggctc gacgggctgg gcggggatcg cgccttcctc gatcaggacg
    19201 gcgagcacct ccgcgagatg ccggcccgag gtggcctcgt tcatctcccg ccactcggcc
    19261 cagccgagaa ccgcgggacc gtcgatgagc atgatccgct ggatcgccgg atcggtggag
    19321 gcaccgagga acgcctcgca ccccacgagc agctgctccc aggacgactc ccgcgcgtcc
    19381 gccgtggcgg cgatccgctc cgccacctcc tgctgcgcct gctccagcac cacccggaac
    19441 agctccgcct tgctgctgaa gtggtggtac agcgccccct tggtcacccc cgccgccgcg
    19501 acgatctcgg acagccccac ggccccgtac cccagagtcg agaacagccg cctgctctcc
    19561 cgtaccagcg cctgccgcgt cagctcccgt tgctgcgccc ggactccctg cggcatccga
    19621 ctgccctccc gtcctagaca tactgaaggt acgccaacac ggtacccccg cgacagggcc
    19681 gcgcccgggg cgggagcgga ggacacactt ccgcaggtca tcgccgcccg cgccccccca
    19741 gcgccggacc tcctcccgcc cgccgcagga gccccgcacc aagacgtgac gacgcgtcca
    19801 cgtcctgcgc ctgccgaggc gccctcgtcc acggggctcg gcccgcccgg caggcagccg
    19861 cccctccgag ccgaagagcg ttgcacgtct gaccggcgca tcagtcagca tctcaatacg
    19921 cccctttgcc agcgcctata ccctccacta gtgttgagtt ttccgcaaca tgcttctacg
    19981 gtcttgcccg tggaaaccga cgaaggcccc gccagcacat cgacagccgg caccgccgcc
    20041 cgcgtccgcg cggtcatcgc ggacgcaggc gtcagccagc gcgagttcgc gcgccgtgtc
    20101 gtcatggacc cgtccaaact ctcgcgtgcg ctgagcggca cccgccgctt cacggtcgcg
    20161 gagctggcac ggatcgcgga cgaaggccgg gtcgacgccg actggctgct cggcacccgg
    20221 ccccgcgaaa gggaaacggc gcccgccgtc cacgtcgagg gcgggcgccc gctgcagatc
    20281 gtccgcgaga cggtccggct gatcgcggag cacggattcc acgcggtccg cgtcgccgac
    20341 atcgcccgtg cctgcgccac cagcagcgcc gcgatccact accacttccc gggccgcgcc
    20401 gaactcctgg aggcggccgt gcgctggtgc atggacgagg acaccgcacg ccgtgccgct
    20461 cacctcgccg aggcggacga cgcggcggcg gagctgcgcc agctcatcgc gctgcagaca
    20521 ccgcgcaccg cacagcagcg ccgccagtgg gcggtgtggc tcgacctgtg ggccgaggcc
    20581 gcgcgctcca cggcggtcgg ccggctgcac tccgagtact accgccagtg gcgggagacc
    20641 gtcaccgacg tcctgcgccg aggtgccggc caaggagtct tccgcgccgg gatcgacccg
    20701 cacgcggcgg cactgacgct gaccgccctg atcgacggcc tcgccaccca cgtcctctcc
    20761 gtgagcgggc cggagtccgc caccgccgcg gacgcgatgc acaggacact gaccacccac
    20821 atcacccaca cgatcctggc tccgtagccc agaaaccacg gacgccccgc ccctgcgccg
    20881 cccccgccgc ggaggcaaga acccgggagg cccccacatg cccatgaccg agaacgtcat
    20941 catcacctgc gccctcacag gcgccggcga caccgtccgc aagagccccc acgtccccgt
    21001 caccccggag cagatagcaa ggaacgccgt cgaggcggcc gccgccgggg cagccgtcgt
    21061 ccacatccac gtacgcgacc cggagaccgg cgatccctcc cgcgacccga agctctaccg
    21121 ggaagtcgtc gagcgcatca aggaaaccgg caccgacgtc gtcatcaacc tcaccgccgg
    21181 gatgggcggc gacctggtca tcgaccccga cgacccgctc acccacctcc ccggcaccga
    21241 cctcgtcggc ggcctggaac gcctgccgca cgtcgaggac ctgctccccg acatctgcac
    21301 actggactgc ggctcgctca acttcggcga cggctccaac ctctacgtct cgactcccga
    21361 catgctgcgc gcgggcgcac ggcgcatcca ggaactgggc gtacgacccg agctggagat
    21421 cttcgacacg ggccagctct ggttcgccaa gcagctgctc gcggagggcc tgctcgacgc
    21481 cccgaccgtc ttccaactgt gcatgggcgt cccctggggc gctccggccg accccggagt
    21541 gctccagtcg atggtcaaca tgctgccgga cggcgcacgt tgggcaagct tcgcactcgg
    21601 ccggatgcag atgccgtggg tcgcccagtc gattctgctc ggcggccacg tccgcgtggg
    21661 cctggaggac aacctgtacc tcggcaaggg caacaaggcg accaacgccc agctcgtcga
    21721 gcgtgccgtg accctcaccg aatcgatcgg cgcacgcgtc gcgacaccgg acgaggcccg
    21781 cgccacgctc ggcctcaaga agcgcaagta gtccgccgcg acgacgaagg gcccctcatg
    21841 acctcacccg agaagacctc acccgacccc acctctccga aggcgaccac ctggaaggcg
    21901 acgcttacgg agaccacctc tccggagaac atccgccgcg tcgcctgcgt cggcgccgga
    21961 gtcatcggcg gcggctgggt cgcccacttc ctggcacgcg gctacgacgt caccgcctgg
    22021 gaccccgcgc ccgacaccgc gcagaagctg cgacgcctcg tcgacgcggc gtggccggca
    22081 ctcacctcgc tcggcctcgc cgagggcgcg tcacccgacc ggctcaccgt gaccgaaacc
    22141 ctcgaacagg ccgtggccga cgccgagttc gtccaggaga gcgcacccga gaagctcgat
    22201 ctcaagcgcg atctgctgac ccgcctggac gcggcgacgc cgcccggcgt cgtcatagcc
    22261 tcctccacct ccggctaccc gatgaccgac atgcagacca cggccgcgga cccgtcacgc
    22321 ctggtcgtcg gccacccctt caacccgccc tacctcatcc cgctcgtcga ggtcgtcggc
    22381 ggcgaacaca ccgacccggc ggcggtcgcc tgggccaccc gcttctacga ggccgcgggc
    22441 aagtccgtca tcacgatgaa caacgaagtc cccggcttca tcgccaaccg cctccaggag
    22501 gccctgtggc gggaagcact ccacatggtc gccaacggtg aggcgacagt ccgggacatc
    22561 gacctgtcca tcaccgaagg gcccgggctg cgctgggcgg tgatgggacc gatgctgacc
    22621 ttcgccctcg ccggcggtga gggcggcatg gcacacatgc tggaccactt cggtccgtcc
    22681 ctgaagtcac cgtggacacg cctcgaagca cccgaactgg acagggagtt gtacgacgcc
    22741 gtggtggcag gctgcgacga ggcggcggac ggccgctcca tcgcggatct ggtcgcggaa
    22801 cgggacaagg gcgtcatcga tgtcctgcgc gccactggcc gcctcggccg cgagggggaa
    22861 gcccgatgac gaagctccct ccgttccgca gcacggtccg cccggagtgg atcgactaca
    22921 acggtcacat gagcgaggcc tactactccc ttgtcttcgg ccacgccacg gacgcactga
    22981 tggccgagac cggcctgggc cccgcctacc gcgaatccac ccgctgctct ctctacacgg
    23041 tcgagtccca catccgcttc ctccaggacg ttcccgaagc cgcccacctg gccatccgca
    23101 cccgcgtgct gggggtggca gcacgcaagg ctcacttcac ccacgagatg tacgtagtca
    23161 gcgccttggg agcggagccg ccagcggacg cgctcccggt ggcgacgacg gaactgctcg
    23221 cggtccacgt cgaccagcag gcgggcaggg ccgccgcttt cccggacacg gtccggcacc
    23281 ggttcgcaga gctgaccgaa ccgcctccgg cctgggcggg ccgctccatc gcttccgtgg
    23341 cctgacacgc acgggcacga accacacgcc cgggccctcg tatcgcgccc gtgccgtgcg
    23401 cctccctctg cgaggagggg tccgggcggt ggtggaggag ggatcccggg ttggtccctt
    23461 tcggctgtca acaccgattg tcagtgctgg atgagacggt aggggtaccg agtcggaatc
    23521 aagggggagt tctcatgtcc gggaatcaga attacatcaa tcacgtggct cttgtactgg
    23581 atgcgagttc gtcgatgtct cgcctgagtg gcaaggtgat tgaggtggct gatcagcaga
    23641 tcgcctatct ggcccgccgt tctcgggagc tggatcagga gactcgtgtc acggtgtatg
    23701 tgttcgcgaa caaggtggag tgtgtcattt atgacaagga cgttctgcgg atgccgtcgc
    23761 tgaagcagct ctaccgggtc ggtggcatga cggcactgct cgcggccact ctcacctcgc
    23821 agcgggagct cgcccagacc gcgcagctct acggtgacca cagctttctc acgttcgtgc
    23881 tgaccgatgg ccaggagaac gccagccacc gctgtcccgg tgccccttcc cagaagccga
    23941 aggaactggt cgcagcggtc gcgcagatga tcgagacgca gcaggacaac tggacactgg
    24001 ccgtcctcgt gccggaccag atgggcaagc gcgaggccat gcagtacgga ttcccgaagg
    24061 acaacatcgc catctgggac gcgaccagca cgcagggtct gcaagaagcg ggtcaggtca
    24121 tccaggaggc cacggagaag ttcatggtgg gccgcaccca gggcatccga ggttcgcgag
    24181 cggtgttctc catgagcgcg gaagtggtca acaaggacac catcaaggcc gccggcctga
    24241 ctccgctgaa cccgtcggat taccacctga tccccgtgac atgcgacgcc gccatccgcg
    24301 actggatcgt ttcgtccggt cacacctacc gcaccggcgg cgccttctac cagctgagca
    24361 aatcggagaa gatccagccc cgaaagcaga tagccgtcct ggaaaagaag acggaccgca
    24421 tctacacggg cccgcaggcc cgcgcactcc tcggcctgcc cgacatcgag gtccgaatca
    24481 agccggacca caacgacgat ttcaccatct tcgtacaaag caccagcgtg aaccgcaaac
    24541 tcgcccccaa cacaagggtc ctcttcatgc cctgaccccg gttcggtgct cactggctgc
    24601 ggctgcgctc aggccggctc ggcagttcgg tgtggacggt cggacggtgt cttcaccccc
    24661 tgtcctcgcc ttcgctgccg cagcttgggc cgtctcttct ggatcaccat gagggttgcg
    24721 gcgaggcggt gtgcgttgct ttcaggtcgc gcggtccgcg acgaggtgga tcttgccgag
    24781 agtgctcacc gctcgtatcc ctgatgcgca tttcgcatgc ttggagttag ggtgtgtcca
    24841 tggtgatgag tactgaggag tgtttgcgtc tgacggtggc tgctctgatg cagctgactg
    24901 gggagcggca gcctgatgtg gctgtggcta ttggtctgac gcagccgcag cttagtcgtc
    24961 gtcagtcggg taaggcgtca tggactttga gtgactgtga ccggcttgcc gctcactggg
    25021 gtatgtccac cctcgatctc ttgtccggtc ctacccatgc cgccggttgt ctgcccgcga
    25081 cccgccgctc caccacgacc ggcacccaga ccaccgtccc catggagccg ccggcccccc
    25141 accgccccgc ccccgcgcct tcctcagggt ctggctcggg cgccccggcc gtgcccgtgc
    25201 ccactgcgtc tgaccccgcc gtgcccgctg cgtccgcccc tgcaccggct gaggccgacg
    25261 ccgcgcctgc ctcggccgct gcgcccgtcc ctgccgtccc tgcggcgccc gagcccgcct
    25321 ccgtgcccgc cgcacctgct ccggccgtgc gcgccgcgtc tgcgtctgcg tctgccgctc
    25381 cggttgtgcg tgctgtgccc agctcgtctc ggcctgcccc ccgtcgcgtg gctccttcgg
    25441 ggtccgtgcc tgatcttgtt cgtgagcgtg tggctgttgc tgttgctgag gtgggtggtg
    25501 atgtcgatgc ggcgcgggct gtgctgatca agcgtgcggt gcctgacgtg atggcgttgt
    25561 tcgcggcttc tcgtgtgggt ggccggtacg agcacagcga gttccctcct accgccggca
    25621 ttctccagaa gcgtcgtcag aagggtgccg acgagatctg ggagggccgg ccgaagtggc
    25681 gtgcagccga cctccaccgc gctgcccacg caggtcacat caccgtggac gtgactgtcc
    25741 tggacatgaa cgccgcctat ctggcggcgt tgaagacgtg gctgcccatc gggaagctga
    25801 cgcactccca gggcgatcag cacgacccca aacgtagcgg tgtgcacctg gtcgacccgg
    25861 gcgagtggac cacccccgac ctcccctccc cgctggggtc gcgacaggag ccagggcccc
    25921 tctggatcac cgaacccacc ctcagggccc tgatccgctg cgccggaatg gatctctgta
    25981 ccccgccgag gatcctggag tcgtggactt ccggagcatc tgaagggctt ctggagaaaa
    26041 tgcggcgggg cctcgtcacg gtcagggacg aggctatcgc cgataacgac gaagtgacca
    26101 cggaatacgt caagtcgatg tattctaagt tcgtctccac tatcggtgag agtgcggcga
    26161 accgagaaat ccggcggccg gactggatgc acatcatccg cagtcaggca ttcgtaaatc
    26221 tgtggctcaa agcatacaag gcacacaagg ccggtctcac cgtcgtacag atgagcggaa
    26281 ccgacgaact gcacgtgtcc ggcaactggc aggaaatctt ccccgaaggc cgcggactca
    26341 gccaggtaaa agccaaaaac acctacacgc tgggaggaaa tgagtgagcg gcgcaagcga
    26401 cctgtgggga gaattcggca aacaccacgc acaaggccag aaaggcgcac aagcactcgg
    26461 ccaggagatc gaacgcatcg cccgccaggg cggcatcacc tcacccgtga ccaccacccg
    26521 cggcctgcgc gcacgcctgc gctacctcga cagcccagca ggccgccggg ccctcgccga
    26581 acacggtgtc tccagccgtc tgcttcgcgc ctgggcggac ggccgtactc ccagccgggc
    26641 gaagctggcg gctgtcgatg ccgcgtactg gggtcgccgc cgagagaatc tggtccggtc
    26701 gggtgcgctt aagcggcttc ttgacaacga gggccggggt cgtcgtatcg agatctatcc
    26761 tgtggaccaa tcagcggtgc cggagaagcg gaagcgggtc atctcgcagc gaacggtcac
    26821 cgcccgctac atctgggatg atgcggttgg cgcatgggcg tccggagatc tcaatactct
    26881 tgatgaaatc tgggatgacg tgatctcaga ccttgactcc gactatgcgg cttacgcata
    26941 cgtcgagtcc atcggaatca gcgcgtagta ctaaagaatg ggtgtggccc ggcagaactg
    27001 ccgggccaca cccattcctt ggcccaaacg atgtaacggt catgcggtct ccgccctgca
    27061 tgcgagaaag cacagaaagg ctacagtgag gccctgacgc gctcccacga gggaaatgtt
    27121 gacaggtgga ccgataggcg ccagcggggg ccgtgaaagt gatctgaggg gtaattaggt
    27181 ttctcccctg cgggcacctt ctctgctgat cgaaaatcag atcctgaccc gtctcatact
    27241 aagtggtgta gaccagttgg caagctccgg aagaacactg tcttgacggt acgtcagata
    27301 acgtcacccc gccatggagg ctaggagacc gcatactgta acggcttcac cgagcgatcg
    27361 gggaagggcc cgggatggcc ggcctcaagc tcatcaagca ccaggaccac gagactaccc
    27421 atcagaaacc tcctgccacg agtagtttga gaagagccac caccgcccca cctcgtagcc
    27481 agccaggggc cggccggagg ccggctttag ggccgaaggc ccggagtggt caccgaaggt
    27541 gaccactcgc cgagggccg
//
