LOCUS       NZ_KV804813            23529 bp    DNA     linear   CON 31-JUL-2024
DEFINITION  Rothia sp. HMSC065G12 Scaffold83, whole genome shotgun sequence.
ACCESSION   NZ_KV804813
VERSION     NZ_KV804813.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Rothia sp. HMSC065G12
  ORGANISM  Rothia sp. HMSC065G12
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
            Micrococcaceae; Rothia.
REFERENCE   1  (bases 1 to 288079)
  AUTHORS   Mitreva,M., Pepin,K.H., Mihindukulasuriya,K.A., Fulton,R.,
            Fronick,C., O'Laughlin,M., Miner,T., Herter,B., Rosa,B.A.,
            Cordes,M., Tomlinson,C., Wollam,A., Palsikar,V.B., Mardis,E.R. and
            Wilson,R.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2016) McDonnell Genome Institute, Washington
            University School of Medicine, 4444 Forest Park, St. Louis, MO
            63108, USA
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: High-Quality Draft
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: Velvet v. 1.1.06
            Genome Coverage                   :: 144x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001811455.1-RS_2024_07_31
            Annotation Date                   :: 07/31/2024 12:58:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,178
            CDSs (total)                      :: 2,120
            Genes (coding)                    :: 2,076
            CDSs (with protein)               :: 2,076
            Genes (RNA)                       :: 58
            rRNAs                             :: 3, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 44
            CDSs (without protein)            :: 44
            Pseudo Genes (ambiguous residues) :: 0 of 44
            Pseudo Genes (frameshifted)       :: 4 of 44
            Pseudo Genes (incomplete)         :: 39 of 44
            Pseudo Genes (internal stop)      :: 2 of 44
            Pseudo Genes (multiple problems)  :: 1 of 44
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:45:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 62823
            Orig. end                         :: 86352
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KV804813.1.
            The WUSC is a large strain collection isolated from clinical
            samples. Each sample is associated with metadata, including source,
            isolation site, 16s rRNA, metabolic, and other phenotypic
            information. The goal is to sample an adequate number of important,
            yet minor species, further adding to the catelogue of sequenced
            bacterial genomes and improving the diversity of the genomes
            available to the public. WGS will be preformed on approximely 550
            isolates. Samples were selected based on RDP analysis at the genus
            level. This is a reference genomes for the Human Microbiome Project
            and the work was funded by the National Institutes of Health (NIH)
            grant U54 HG004968.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23529
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23529
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23529
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13529](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13529
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            complement(974..2368)
                     /locus_tag="HMPREF2804_RS03320"
                     /old_locus_tag="HMPREF2804_03325"
     CDS             complement(974..2368)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004006025.1"
                     /locus_tag="HMPREF2804_RS03320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2804_03325"
                     /product="hypothetical protein"
                     /protein_id="WP_070627292.1"
                     /transl_table=11
                     /translation="MYGRADDRAQAPSRSSLPPGYAEFHQQFGTLITALAAQGWTPSET
                     HRRIRVLFPQVNREHLDFALDSGMWEFGSHGEQTPTHVLLATAVWYAVAEAYGLAPDGS
                     YAATTLDATVMADMLRLLESARVSPQNIALILGKVGAGLKYLALHPYTQLDELTYRDVC
                     QHLPTESQDVAHGSFVWPPSCESIRDQLGDGGWSTAMLRTGVCPPDYADYNWQLGGTSL
                     TDMEFRNQLGSFMSYCIRYDRQPTVLAYGTWSTMRSNLGRVPFLAAVRAKYGSWRTALQ
                     VGRTMVTDALQMTKREVAPVRVPPHPPSISPEQLAVQGIGVVKSEQTVSARDRWDEVTN
                     SLGQRLASLPWSRHLRTYYVLTGAANANAMPLVCIYRSPAGFLCEIAMEAEVLPKFSTD
                     YLRSHGWAAPTPMQPMWNRNVFDPHEAAQDVVQAMRWGMGCSRWDYYRTDDLVLDAEDT
                     SGTEAG"
     misc_feature    complement(2346..2366)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.31"
                     /tool="antismash"
     misc_feature    complement(2458..2472)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.87"
                     /tool="antismash"
     misc_feature    complement(2477..2493)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.33"
                     /tool="antismash"
     gene            2609..5044
                     /locus_tag="HMPREF2804_RS03325"
                     /old_locus_tag="HMPREF2804_03330"
     CDS             2609..5044
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013398539.1"
                     /locus_tag="HMPREF2804_RS03325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2804_03330"
                     /product="Tex family protein"
                     /protein_id="WP_070627294.1"
                     /transl_table=11
                     /translation="MSEKHERTEATNTRILTMLSNELDLKPTRVRAAVNLLDSGSSVPF
                     IARYRKEATGALTDTHLRAISTRLDALRALETRRENILSSLAQRREDGLIDPLTYEQLI
                     TGVGAASSKQDLEALYTPYRSERITKAQRARAAGLEALVEDLLEVPLAGVYDIAAAYVD
                     GPDETDDKQVADTGKSEDARITTVEEALDGARAILIDRALTDPTLAERLHERMVATGTI
                     SSRVIAGREAEGAKFADYFDFSDSIRRIRPHRVLALLRAKEAGIVRLSIDGATPAPPLS
                     KLRGEARAAALALAENYENVRSGYEREVAAALRIPVQVLNTVDSEDRVLGWLAATVRTA
                     WRKRLHPRLADRIRNALFEMAEREAITVFASNLRDLLLAAPAGQKVTLGLDPGLRNGVK
                     CAVIDGTGHVLKTFTVYPHAPRYDRADALAALEDAVLTHGVELIAIGNGTASRETDKLA
                     AELLAKLRSQGYKAAQKVTVSEAGASVYSASELASEELPDLDVTVRGAVSIARRLQDPL
                     AELVKIDPQSLGVGQYQHDVSVTALRRALDNTVEDCVNAVGVHLNSASAALLARVAGFN
                     RTIAENIVAYRDEHGAFTTREELLNVPRLGAKAYEQAAGFVRILHGTEPLDASAVHPES
                     YPVARRIIADAQRNHGALWQSGRLIGSDGEDPLTALDPADYVNGSIGEYTVRDIFEELR
                     RPGRDPRPEFRTAHFSEDISRFEDVTVGMVLEGTVSNVAAFGAFVDIGVHQDGLIHISQ
                     MSREYVANPHDIVRNGDIVTVRVVEVDASRRRISLSLLLDEGDSGRSETAHKKTNKRS"
     gene            complement(5259..6086)
                     /locus_tag="HMPREF2804_RS03330"
                     /old_locus_tag="HMPREF2804_03335"
     CDS             complement(5259..6086)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013398540.1"
                     /locus_tag="HMPREF2804_RS03330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2804_03335"
                     /product="aldo/keto reductase"
                     /protein_id="WP_070536271.1"
                     /transl_table=11
                     /translation="MVKNITFNDGNSIPQLGYGVWQIEDNGAADAVGTALEAGYRHIDT
                     ASIYGNEVGVGRGIAASSVPREDIFLTTKLWNSDQGFEKAIAALDASLERLGTDYVDLY
                     LIHWAMPQQGTYLESWRALIELKKQGKVRSIGVSNFPQAQLREIIADTSVTPAIHQIEL
                     HPYFSQEDMRAVHSEFGIVTEAWSPLGQGGEILKDPVIVEIAGKHGISPAQVVLAWHLA
                     KGIVAIPKSVTPARIAENFAAANVTLDAADIAAIDGLTRKDGRIGPDPENPKF"
     misc_feature    complement(6133..6147)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.92"
                     /tool="antismash"
     misc_feature    complement(6267..6281)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 20.24"
                     /tool="antismash"
     gene            6463..6777
                     /locus_tag="HMPREF2804_RS03335"
                     /old_locus_tag="HMPREF2804_03340"
     CDS             6463..6777
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HMPREF2804_RS03335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HMPREF2804_03340"
                     /product="hypothetical protein"
                     /protein_id="WP_141745423.1"
                     /transl_table=11
                     /translation="MMTALVTTKVNALAAARTFGTAAGSPAHRRALVANPSEVLAEAGV
                     VPSGTQVRLVEDETLTLGHHKVVDDGEELVIAIAPAVEEELDTTESPEDGICWCCCCPC
                     "
     gene            6969..8195
                     /locus_tag="HMPREF2804_RS03340"
                     /old_locus_tag="HMPREF2804_03345"
     CDS             6969..8195
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="HMPREF2804_RS03340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2804_03345"
                     /product="cytochrome P450"
                     /protein_id="WP_083296720.1"
                     /sec_met_domain="p450 (E-value: 6.8e-17, bitscore: 55.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFTYDNGLVQMPEPPHLFTSAWYESPISSALAWQSHAPEGIGAS
                     DISGVLLATRFESVKTVLHDDQRFSAVGQKHLSQMQSQAHYAKPEPADFQIPQTQQRFL
                     AHMDGSPLRQMRKRLRTPFTAANSKKAVERCRDAIEQSVTMLTQSKKLDLAGWCDDLAV
                     SLISVLIGYEGDIIELSRWCRKRGTVPSKREGKLSAPDAHQLFAEDVMGAGGFYHQYRH
                     DGMPHDAAVEIVSMLASITHESLQWAMTNVLTVLTQRNLWETVNYENSIAMVDEALRLY
                     TPTAALGRLATVDTKIGGTSIRAGELIVCLLHAAQHDSRMFPNHDEFTLGRPHASEVTF
                     GMGPHACLGFPIARPLMGAVTHKIAESACTLRLGENPEPLPEMINSTWIQMPVHLIPSI
                     SGENLYAGI"
     gene            8182..9138
                     /locus_tag="HMPREF2804_RS03345"
                     /old_locus_tag="HMPREF2804_03350"
     CDS             8182..9138
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="HMPREF2804_RS03345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2804_03350"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_070627296.1"
                     /transl_table=11
                     /translation="MQGYEQYSVIAEDIHQNYSDVKVLKGVNLAVERGAVHGILGPNGA
                     GKSTFVDLCTGSSKPTSGTVQVLGVDPHRNSALVRSHMGIVMQEAAFPTGLKVKDAVTC
                     WQRYMSATEYTVPEFFDLEKLADRRIHELSGGERRKLDLYLAMMGNPSLLILDEPTTGL
                     DPLARRDVWEVIQNLAETGTTILLTSHYLDEVSALCQQLSILLNGQIVASGTPAHIAKE
                     YSHTRQGWVELSDCQNAQALGGDLSSQSGYKNIRVHDATVSFDVESPTGLQNLFATSAY
                     RDAVLDFALSDYSLENAYGSIVRSTDAPQGIGSTRTD"
     gene            9152..9991
                     /locus_tag="HMPREF2804_RS03350"
                     /old_locus_tag="HMPREF2804_03355"
     CDS             9152..9991
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013245.4"
                     /locus_tag="HMPREF2804_RS03350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2804_03355"
                     /product="ABC transporter permease"
                     /protein_id="WP_070536268.1"
                     /transl_table=11
                     /translation="MSATISNFTRSLYAQIAMQLTVFIRNMRSVFFTLAFPIMMIVLFA
                     SGSSGQANIPAQQGVDVTMASWTIVGLCCYTLLMGTFVRVAGDMAAQRSTSLLKRLRLR
                     STSDAAVIAGYIVTASIIALACTLILIVFGMAVYHLPMPKNIPLTVLVILLTTVVLSLI
                     GAAYASFIPSAEATQIMLLPPALVLMFLSGIFQPVWTIPAGLRDFAGWFPLVHLTDALR
                     SAWFGLDVAHAQVSDTGLTIPSGTQFISTQGMLVIGLWCAVSLIFAITKFRWDPRQH"
     gene            10001..12256
                     /locus_tag="HMPREF2804_RS03355"
                     /old_locus_tag="HMPREF2804_03360"
     CDS             10001..12256
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014661.4"
                     /locus_tag="HMPREF2804_RS03355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2804_03360"
                     /product="YcaO-like family protein"
                     /protein_id="WP_070627298.1"
                     /sec_met_domain="YcaO (E-value: 2.4e-79, bitscore: 261.4,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITASLDNHSETAELYPQGTERYVRNPQFHFTQQTRENRTTVVAS
                     SPETTVLLEGREAEFITEVDGKTLEDMMRLPRWAADLPLMFALAAQLQYRGLIMTETQL
                     SDHTTQGNIEIIDVTRARVLESFSASPQDGIRVIDGHTVPRVNSGLPAVIVCEDMISPA
                     AEKLSRKYEAAGHLYCLVQLQGADALISPVLGTSSSVPYDQLKHSLQVNAQYALSGGKL
                     LDNVMGAASVTPRSVVRSLIWLAIQRMKTSEPAERTVLRFKNGLFEGEHYVMTGAKTTK
                     AQPLNLDAQAKKIDLSFNPVNDAGRAKSTRETWETYRHLVSDVTGVVSSLKRLVPEDEE
                     LLVHVYGAGHNWALNHGSSEEFTRSLRGRSSGKGTTDLGARVSGLAEAIERHSAISDGT
                     EARLHTSYKDLGEHALDPRTLTQFSQDQYEQRDVLNQVKDPYHWVPEKFDPTAEIDWMP
                     VWRPACDETAWIPAAYSLFMFDHGAMLPGAKCPLGQKMMRSDSNGLASGSTPGDAAAQA
                     LLELIERDAVAIWWYNKIPRQIMAPEFTDTPFIQRTREWLRSIGRNLEILDITTDIGIP
                     VAAAVAPKPGDASDQIILGFGAHPNPEIAATRAVTEALQFMCALPAQFRTAEGMDLDLL
                     KISVDDAASHWLQNAKLADNPHLVPDPQALNVEHVPWKQADPQRIIARLEDVGLPVYLQ
                     ELTRPYIGLPVVRALVPGLRPWWRRLATGRLYDVPVQCGWLAQPTQETDLNPTSMFF"
     gene            12270..13529
                     /locus_tag="HMPREF2804_RS03360"
                     /old_locus_tag="HMPREF2804_03365"
     CDS             12270..13529
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013077.4"
                     /locus_tag="HMPREF2804_RS03360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2804_03365"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_070627299.1"
                     /sec_met_domain="PF00881 (E-value: 1.1e-09, bitscore: 32.5,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKTHLNPHKIPLIHCEYQLKQTHPQNNGKFGTLEDWAQNLDVSA
                     QQAALILTRQSSSRNLIQRLINPETGASIEISGFELLLTEDALEPVLDEANYPLGHTDC
                     TLTPGVVIYGMNGNTRLEIAHRPLRITLNAQAWLDAMTGGVTHKILEFIGIFAPEAQHH
                     KYGPWDCWEPHDYFMYRRSRFDTATGGYGATRTREHNTTLLKGLASLRQVSFPKVDSRR
                     HQLLLDQALLQRTSRRIPQKPSLSLESLTTLLEESLRETSHKSENITRLPFPSGGALHE
                     LYPFIIAQNIEGLEQGLWYANLHTRQYEQVAAVEEKTQSAYMRLLRTYASSARLKTEDV
                     QGLVLLAADFDLVTSTYEGVAYSLTLKHVGAWMQTACLLAEEIPLNVCPLGGGDARAFE
                     TLTGVSSDRLVPVGEILVSS"
     gene            13554..14621
                     /locus_tag="HMPREF2804_RS03365"
                     /old_locus_tag="HMPREF2804_03370"
     CDS             13554..14621
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="HMPREF2804_RS03365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2804_03370"
                     /product="sensor histidine kinase"
                     /protein_id="WP_070627301.1"
                     /transl_table=11
                     /translation="MFDTYGIWTALAWCALVLAAVWIGYLRIQRPTVGKIHSIVSIIII
                     IFSLVGILGIKQSMLPVGILCCAIAVTGVRNTKIAAITTLAVVVALNYLQTLEPSWEIN
                     TSSHDPAIVAIVGFLFMNLRISRVSHRRLQEELYIAEQNQELREQNLQAEFRTQIAANL
                     HDLIGHDLTVINIRLQQLVRTLKPLDSDVAHEARAIQKMTRSSIAHLRDVVEGFNTVDF
                     SHQLNAVPSLLSYRGIQAHMDIQQNVLKVLNPSTLTALYWVLLEAITNVLKHSGAKNCW
                     VSLKQHSSGDYMLIIADDGIGLKESSMRNTGAGLADMNTRIQHIGGETTLGAAPEGGTQ
                     VRARIPASNIITGGA"
     gene            14626..15231
                     /locus_tag="HMPREF2804_RS03370"
                     /old_locus_tag="HMPREF2804_03375"
     CDS             14626..15231
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.4"
                     /locus_tag="HMPREF2804_RS03370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2804_03375"
                     /product="DNA-binding response regulator"
                     /protein_id="WP_004006035.1"
                     /transl_table=11
                     /translation="MITVLIADDQTMFGSALASLIDEEEDLEIVCVCRDGQEALDSIVT
                     YIPNVALLDIEMPKLNGLDVLDEVQKQGINTKIAILTTFQSPGYVRRALESGACAFITK
                     DQDAEEVSNIIRDIHSGKVVVDSALLLSGATLPANPLKPRHQDVLKLTMEGKTVNQIAR
                     ELYLSHGTVKNYLSEAIQLLHCTSRVEAAHTARTNGWI"
     gene            complement(15308..18001)
                     /locus_tag="HMPREF2804_RS03375"
                     /old_locus_tag="HMPREF2804_03380"
     CDS             complement(15308..18001)
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012403.4"
                     /locus_tag="HMPREF2804_RS03375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2804_03380"
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_246824114.1"
                     /transl_table=11
                     /translation="MHWKSTRKGALDAPHRDVFQAQSSQQAEESAGENENSETQTGGLI
                     PELSLENAAMPTIPDLPEGLNLAFIPLAEPLDAVAESLVSRGEMRIPAGEREAFHREFL
                     PTLTRAVPFLTPDPALALPKVRSPYLVFEAHFDDEISHDALLNWYWEYPKNPLDEEGTD
                     SGVRRLPALGLGTERDERFEARVLRAVRSATASNPVLAGGFGERRSQGWETRDILAHVL
                     PALRCISGVRVRLLGSVPEFTEATDAMIEVKVTEGNSRDWFGLGIAIKVNNWTVPFAQV
                     FEALDRNQDRILLGNGTYFSLNRPEFSALRTLIEEARTLNETGGELRINRHQAGLFSEL
                     ESLASSVETVASWDAQVKSLLALVEAADRAGETAGSEEVLENEHSDSLSVSSGVFSANH
                     LPSPPGLTAVLRPYQLEGFRWLAFLRQHRLGGILADDMGLGKTVQVLALLAQAIAEHEQ
                     RADHTEFEPFLVVAPTSVVGNWAQEAARFVPGAKVVTITESTGKSGKSIAELVQGAHLV
                     LTSYALFRLDEDGYTEFGNHVPKNTENGASPHAGWGALILDEAQFVKNTKTRAWKVARA
                     LNAQVKLAITGTPMENNLMELWALLVIVADGLFPSARMFRDLYARPAESGEDPQVIEKL
                     RRRVRPLMLRRTKDVVAADLPEKNDVRVNVPLTTAHRHIYDMHLQRERQKVLGLLEDMD
                     KNRFTIFQSLTLLRRLALDATLIDPDEYAGVASAKLEYLVEHLPSLLGDGHRVLVFSQF
                     TGYLRTIAERLQAEGIDYLYLDGTTRNRPQVLKDFAEGAAPVFLISLKAGGFGLNLTEA
                     DHCFIMDPWWNPAAEQQAVDRIHRLGQERDVHVYRLVAEGTIEEKVMDLKASKAALFDA
                     VVNDGSFASSRVDAEQIRELFTPTDS"
     gene            complement(17968..19263)
                     /locus_tag="HMPREF2804_RS11265"
     CDS             complement(17968..19263)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016330.4"
                     /locus_tag="HMPREF2804_RS11265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SWIM zinc finger domain-containing protein"
                     /protein_id="WP_246824115.1"
                     /transl_table=11
                     /translation="MSAPNPFPDIPVTVAQIIRQAGHKAYQRGLAYARQREVVRYTYDE
                     DENTLEGLVNGSTPIPYEVGIRFFPGSDADSNLFNARCTCPVAADCKHAVALMLTALDR
                     AKTARKALDNTPGGRIRQSMNPESPEDTARQVAEAADDPLAALRASGAIRSASSLTTDP
                     KPLPLNDHENTHSSPSKISVWRRDMAQVLAARGEASGIDSARVPGALDLSFSISGSYAR
                     GRNIPGATPPINLLARPLMQSKTGRWIKGGLSWETFASSVGGPVGRHEVYPEHERFFAE
                     IYAIARPWQNMYSSHRDWISLTATNSTLLWDVLARAEQIGLPILLEGFEVTTAVLPPAQ
                     VRVHAGAVEAESRQNAEAAMSEDSAPDLALHAALGWETREDNRVRQLWFDAGHATPSAR
                     HARGFSRSVLLCSVFTRNRRIECIGRARARAP"
     gene            complement(19308..19595)
                     /locus_tag="HMPREF2804_RS03380"
                     /old_locus_tag="HMPREF2804_03385"
     CDS             complement(19308..19595)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004006037.1"
                     /locus_tag="HMPREF2804_RS03380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2804_03385"
                     /product="hypothetical protein"
                     /protein_id="WP_070627303.1"
                     /transl_table=11
                     /translation="MKTARMVGAIAALLLILGIGLFILAGGGSVVEYHAFEWRGVQPKG
                     SSPLTQAAATLAMSVLCVGFLTGIITFIMFFTISIKNTCKKRSAHHGQTS"
     gene            complement(19619..19945)
                     /locus_tag="HMPREF2804_RS03385"
                     /old_locus_tag="HMPREF2804_03390"
     CDS             complement(19619..19945)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004006038.1"
                     /locus_tag="HMPREF2804_RS03385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2804_03390"
                     /product="hypothetical protein"
                     /protein_id="WP_070627305.1"
                     /transl_table=11
                     /translation="MKKAIYIVGAVAAVLLVIGFGLLILAGWGSLVEYHAFEWRGVDPA
                     GASPLVMATNNLSLWFLGIGFLTGIITFILLFTTATKKARKAQNKHVEQNKTPLAKERD
                     QMNP"
     gene            complement(19968..20294)
                     /locus_tag="HMPREF2804_RS03390"
                     /old_locus_tag="HMPREF2804_03395"
     CDS             complement(19968..20294)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013398544.1"
                     /locus_tag="HMPREF2804_RS03390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2804_03395"
                     /product="hypothetical protein"
                     /protein_id="WP_070627431.1"
                     /transl_table=11
                     /translation="MKKTVQIMGIVAAIFLIIGFGLFILAGWGSLVEYHALEWRGVQHK
                     GASPLTRATGNLSYWFLGTGFLTGFIALIPFFTTAVRNSRKTHKKHPVQVQNLLEEGQN
                     QIDL"
     regulatory      20559..20687
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00634"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00634"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM riboswitch class IV; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            20666..20944
                     /locus_tag="HMPREF2804_RS03395"
                     /old_locus_tag="HMPREF2804_03400"
     CDS             20666..20944
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904100.1"
                     /locus_tag="HMPREF2804_RS03395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2804_03400"
                     /product="nuclease PIN"
                     /protein_id="WP_238382392.1"
                     /transl_table=11
                     /translation="MVQARATRKERAFGAWLSMYNSSSSPASPLTPARSYQENLRAASV
                     PARGGYQAVSIQDYARISSKRDEFLNFLLLPNPEGIPAVEYAGLRVA"
     gene            20949..21383
                     /locus_tag="HMPREF2804_RS03400"
                     /old_locus_tag="HMPREF2804_03405"
     CDS             20949..21383
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013398546.1"
                     /locus_tag="HMPREF2804_RS03400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2804_03405"
                     /product="plasmid stabilization protein"
                     /protein_id="WP_070627307.1"
                     /transl_table=11
                     /translation="MSASGLLLDSDVLAEIRKATPDSKVVAFLRRRAYKHLYISVLSVG
                     ELKGLYPYPETDRWIAELLDRFADHIINVDARVSLEWAGRSAPRGIHSHGRKDAEPLPT
                     AALEGLMAASAQAHDLEIVSSKAEVYRSWGVPAVNPWIED"
     misc_feature    21390..21405
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.53"
                     /tool="antismash"
     misc_feature    complement(22329..22341)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.6"
                     /tool="antismash"
     misc_feature    23182..23199
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.41"
                     /tool="antismash"
ORIGIN
        1 ttcttaggcg ccttccagat cgcggtcttt gcctttatgg ggtccgagct ggtaggtact
       61 accgccgccg aaacccagaa ccctacggtg accctgccga aggctatcaa ctccgtgccg
      121 gttcgtattc tcatcttcta cgtgggcgcc ctggtcgtta ttctgatggt aaacccctgg
      181 cgtgaaattg atccggccaa gagccccttc gtgaccatgt ttaccctcgc cggtattgct
      241 attgccgcgc atatcgtgaa cattgtggtg ctgacctcgg caacatcatc ggcgaactcg
      301 ggtatcttct cgacctcgcg catggtgtac ggtctctccc aagaaggtta cgccccgaag
      361 ttcctcggta acctttccgg gagcggtgtg ccccgcaacg cactgttcct cacctcgatt
      421 ctgctgctct ccagtattgc cctgctctat gctggcgact cgattattga ggcgttcacg
      481 ctggtcacca cgatggcggc agtacttgtg atcttcgtat ggtcgatgat cctcgtcagc
      541 tacctgtgct accgtgcaaa gcgccccaac ctgcaccggg agaccaccta ccccatgccc
      601 ggcggcgtgg tagcatgctg gatcgtgctt gcgttctttg ctttcatcat tgggattctt
      661 gctaccgata aagacactct caccggtttg atgctcatgc ccatctggtt cattctgctg
      721 actatcgggt ggtttgtgaa gaacagcatc aaccccgaaa tcccggagac cagtattacg
      781 cagtcgcatc cggtggtgga tatgaaggca ccgaagaaca acaagtaagg atactccggc
      841 ggatatctgt tccgcattac ttccggtata aaaaggctct tgatgtgaat ggggcggcgt
      901 tactagcgct ttttcacatc aagagccttt tagcgtgata ggggaggaga aacggaagaa
      961 ttcgcgcccc ggcttaaccg gcttcggtgc ccgaggtatc ctcggcatcc aacaccaggt
     1021 catccgtgcg gtagtagtcc cagcgggaac agcccatacc ccagcgcatt gcctgcacca
     1081 catcctgcgc ggcctcatga gggtcaaaaa cattccggtt ccacataggc tgcatggggg
     1141 tcggcgccgc ccacccgtgc gaacgcaggt agtcggtact gaacttgggc aaaacctcag
     1201 cctccatcgc aatttcgcac aggaacccgg cgggggagcg gtagatgcac acaagcggca
     1261 ttgcgttagc attcgcggca cccgtgagca catagtaggt gcgcagatgc ctgctccagg
     1321 gcaggctcgc caaacgctga ccgagtgagt tcgtcacctc gtcccaacgg tcgcgggcag
     1381 aaaccgtctg ctcagatttc acaaccccaa taccctgcac cgcaagctgc tcgggcgaaa
     1441 tacttggcgg atgcggcggc acccgcaccg gtgcgacctc tctcttcgtc atctgcaggg
     1501 catcggtcac cattgtgcgg cccacctgca aggcggtacg ccacgatcca tatttcgcgc
     1561 gcaccgccgc cagaaacggc acccggccca gattactgcg catggtagac caggttccgt
     1621 aggcaagcac cgtcggctgc cgatcatacc gaatacagta actcatgaaa ctgcccagtt
     1681 ggttgcggaa ctccatatcc gtgagcgaag taccgcccag ctgccagttg tagtccgcat
     1741 aatcgggcgg acacacaccg gtgcgcagca tggcggttga ccacccgcca tcgcccagct
     1801 gatcacgaat gctctcgcag gagggcggcc atacaaacga accgtgcgct acgtcttggg
     1861 actcagtcgg aagatgctgg catacatcgc ggtaggtaag ctcatcaagc tgcgtatacg
     1921 gatgcagcgc caggtacttg agcccagcgc ccaccttccc taaaatcagg gcgatattct
     1981 gcggtgaaac ccgtgcactc tccaataagc gcagcatatc cgccatgacc gttgcatcca
     2041 gagttgttgc ggcgtaggaa ccatccggtg ccagaccgta agcctctgcc accgcatacc
     2101 agacggcggt cgccagcaaa acatgggtgg gagtctgctc gccgtgcgaa ccaaactccc
     2161 acatgccaga atctaaagca aaatcaagat gttcccggtt aacctgcgga aaaagaacac
     2221 gaatacgccg gtgcgtttcg ctcggagtcc agccttgcgc agccaaggcg gtaatcagcg
     2281 tgccaaactg ctgatgaaat tccgcgtacc ccggcggcaa agacgaacgt gaaggcgcct
     2341 gtgcgcgatc gtcagcacga ccatacatgc gaaaccttct ttcagccatt ccaccgtgaa
     2401 ccggctaccg tcatgtcatc ttctatgccc cggcgcataa cttctgcaca atcgccggac
     2461 tatctgaaaa atagcgatgt gatgttatta cctattctag atgcgggacc atagctgtaa
     2521 aatttattac gctccgatgc gcaacatacc ctgcgccgca cgccccacaa gactggcaca
     2581 gcacacccga gaatgcgaaa ctgagagaat gagcgaaaaa cacgagcgca ccgaagctac
     2641 gaacacccgc atcctgacga tgctctctaa cgaactagac ctcaaaccca cgcgtgttcg
     2701 tgccgccgta aacctgctcg actccgggtc ttcggttccg tttatcgctc gataccgcaa
     2761 agaagctacg ggcgcgctca ccgacaccca cctgcgtgct attagcaccc ggctcgatgc
     2821 cctgcgcgcg ctcgaaactc gccgcgagaa tattctcagc tcgctcgccc aacgccgcga
     2881 agacgggctg atcgatccgc tcacctacga acagctcatc acgggggtgg gggcggcatc
     2941 cagtaaacaa gacctcgaag cgctctacac accctaccgg agtgagcgca ttaccaaggc
     3001 gcagcgtgcc cgcgcggcag gtctggaggc gctcgttgaa gacctgctcg aagttcccct
     3061 tgccggggtc tacgatattg ccgcagccta tgtggacgga ccggatgaaa ccgacgataa
     3121 acaagtggca gataccggaa aatccgaaga cgcccgaatt acaacggtgg aggaagccct
     3181 cgacggcgcc cgcgctatcc tgatcgaccg ggcactcacc gacccaacgc tcgccgaacg
     3241 tcttcacgaa agaatggttg ccaccggaac gatctctagt cgagttatcg ccgggcggga
     3301 agccgaaggg gcaaaatttg ccgactattt cgacttctcc gatagtatca ggcgtattcg
     3361 tccgcaccgg gttctcgccc tgcttcgcgc caaagaagcc ggaatcgtgc ggctcagtat
     3421 tgacggtgcc acaccagctc cgcccctgag caaactccgc ggtgaggcac gtgccgccgc
     3481 acttgccctt gccgaaaatt acgagaacgt tcgttcggga tacgagcgtg aagtcgccgc
     3541 cgcgctgcgc atacccgtgc aggttctcaa caccgtcgac agcgaagacc gtgtgctcgg
     3601 ctggctcgcc gcaaccgtgc gcaccgcatg gcgtaaacgg ctgcaccccc gcctggcaga
     3661 ccgcatacgc aacgccctct tcgagatggc agaacgcgaa gccatcaccg ttttcgcctc
     3721 gaacctgcgc gaccttctgc ttgccgcgcc cgccgggcaa aaagtcaccc tcgggcttga
     3781 cccagggctg cgtaacggcg tgaaatgcgc ggttattgac ggcaccgggc acgtgctgaa
     3841 aaccttcacg gtgtacccgc acgcgcctcg atacgaccgt gccgatgcgc tcgctgccct
     3901 tgaggatgcg gttctcaccc acggcgtgga acttatcgct atcggcaacg gcaccgcctc
     3961 acgtgagacc gataaacttg ccgccgagct gctggcgaag ctgcgttctc aagggtataa
     4021 ggcggcacag aaggttaccg tatcagaggc gggggcatcc gtatattcgg cctctgaact
     4081 cgccagcgaa gagctgcccg atcttgacgt aacggtacgc ggggcggtct cgatcgctcg
     4141 gcggctgcaa gacccgctcg ccgaactcgt caaaattgat ccccagtctt taggcgtggg
     4201 gcagtaccag catgacgtta gcgtgaccgc tttaagacgc gccctcgata atacggttga
     4261 ggactgcgta aacgcggtgg gggttcacct gaacagcgca tccgccgcac tgcttgcgcg
     4321 tgttgccggt tttaaccgca cgattgccga aaatatcgtg gcgtaccggg acgaacatgg
     4381 ggctttcacc acccgggaag agcttctgaa cgtgcctcgg ttaggggcta aagcctatga
     4441 acaggcggcg ggattcgtgc gaattctgca cggtaccgaa ccgctggatg cctctgccgt
     4501 gcaccccgaa tcgtaccctg tggcgcggcg tattatcgcc gatgcgcagc ggaatcacgg
     4561 ggcactctgg caatccgggc ggcttatcgg cagtgacggg gaagacccgc tcaccgcgct
     4621 tgaccccgcc gactacgtga acgggagcat cggcgaatac accgtgcgcg atatttttga
     4681 ggaattgcgc cgccccgggc gtgacccgcg ccccgaattt cgtaccgcac acttctctga
     4741 ggatatctct cgctttgagg acgtaaccgt tgggatggtg cttgagggaa ccgtctcgaa
     4801 tgtggcggct ttcggtgcct tcgtcgatat cggagtgcac caagacgggc tgattcatat
     4861 ctcgcagatg agccgcgagt atgttgcgaa cccgcacgat attgtacgaa acggcgatat
     4921 cgtgaccgtg agggttgttg aggtggatgc gtctcgccgc cgtatttcgc tctcactgct
     4981 gttagatgag ggcgactcgg gtcgctcgga gacggcgcat aagaaaacga ataaacgttc
     5041 ttgatagggg tggcagcatg cttcaccggg cggaggcgga tacaacgatg cgtgctcaaa
     5101 caactgacag cattatgtct gcgaccgtgg gcggtcttgc cagtcatgct gtcagaactg
     5161 cgccgctatc gtatatccgc ctccgcacga aatatggtta aaaattttcc ggcttcgagc
     5221 cccaacaact cacggcaaag cttcgcggta cgttgcgcct agaatttagg attctcaggg
     5281 tccggaccta tgcgaccatc cttccgcgta agcccatcaa tcgccgcaat gtctgccgca
     5341 tccagggtga cattagcggc cgcaaagttc tcggcaatgc gcgcaggagt aaccgacttc
     5401 ggaatcgcca cgatcccctt cgccagatgc caggcgagca caacctgcgc cggagagata
     5461 ccgtgcttac ccgcaatctc aacgatcacc gggtctttca gaatctcgcc accctgaccg
     5521 agcggcgacc aagcctcagt cacaatacca aactcactgt gcaccgcgcg catatcttct
     5581 tgcgagaaat atgggtgcag ctcaatctgg tgaatcgccg gggtcacgct ggtatcggcg
     5641 ataatttcgc gcagctgagc ctgcggaaag ttagagacac caatcgaacg caccttacct
     5701 tgctttttca actcaatgag cgcccgccac gactcgagat aggtaccctg ctgcggcata
     5761 gcccagtgaa tcagatacaa atccacgtaa tcggtgccga gccgctctag cgatgcatca
     5821 agcgcggcaa tagccttctc aaaaccctga tccgagttcc agagcttggt ggtgagaaaa
     5881 atatcctcgc gcggcacgga gctggcggca ataccgcgac ctaccccaac ctcgttccca
     5941 taaatggatg cagtatcgat gtggcggtaa cctgcttcga gagccgtacc gacagcatcg
     6001 gcggcaccat tatcctcaat ctgccacaca ccatacccaa gctgagggat gctgttgccg
     6061 tcattgaacg tgatgttttt gaccattact tctcctgaaa gttgatgggg actgacgttt
     6121 tcaacggtac ccctggatgc gctcgcacgc tagggtgacg ggcgcatcca gcccagcgcg
     6181 aaaccggtaa gcccctccca ggcgcggaaa aagagccttg atttatataa agcgtgaaga
     6241 atcccgattt attcgtataa agagcctttt tagattcaga aagtacaaaa agtatgagct
     6301 gtagagataa acgggatttg aattctgccg atcagaaagt cacatgacta tagtcataca
     6361 ttcttactga cgttacggca ctgcctgtaa agagttttct tcgagagact ggaatagccg
     6421 ggatagaaaa ggcttctatc caatcggtgt tctaaggaga atatgatgac tgcactagtc
     6481 accactaaag tcaatgctct tgcagccgca cgtactttcg ggacggcagc gggtagcccc
     6541 gctcaccgcc gtgcacttgt ggcaaatccc agcgaggttt tggctgaagc aggcgttgtt
     6601 ccctcaggaa ctcaggtccg cctggtagaa gatgaaaccc taactctggg gcaccacaag
     6661 gttgttgatg acggggaaga actcgtcatc gcaatcgctc ccgcagtcga agaagagctt
     6721 gataccaccg aatcccctga agacggtatt tgctggtgct gctgctgccc ttgctaagtt
     6781 ctgaagggct ataaacaacg atgggaacca ggctattaaa gcttgagtac tagcctggtt
     6841 cccactctgg atacacagtg aaggaaaatc atgaaaaagc gttcaacagg tcgttgggtt
     6901 tttcgtggag cgttactcgt cggatttttg cttattaacg cttcagccaa tcattggtgg
     6961 ccgttcctat gacttttaca tatgacaacg gattagttca gatgcctgaa cccccgcatc
     7021 tttttacatc cgcttggtac gaatctccta tttcgagtgc tctagcctgg cagagccacg
     7081 ctcctgaggg tattggggca tcagatattt ctggcgtttt gttggccact cggtttgaga
     7141 gtgtcaaaac ggttttgcat gatgaccaaa ggttctctgc tgtgggacaa aaacatttga
     7201 gtcaaatgca gtcccaggca cactacgcga aacctgagcc tgcagatttt cagattcctc
     7261 aaactcagca aaggttctta gcgcatatgg atggatcccc tcttcgccag atgcgcaaaa
     7321 ggctacgtac tccttttacc gctgcgaatt ctaagaaagc ggtcgaacgt tgtcgagatg
     7381 ctatcgagca gtccgtcacg atgctcacgc agtcgaaaaa gctagatctt gcagggtggt
     7441 gtgatgatct cgcggtatcc ctgattagtg ttcttatcgg gtatgaagga gatattatcg
     7501 agctttctcg atggtgccga aaacggggta ctgtcccgag caaacgagag gggaaactct
     7561 ctgctccaga cgcgcatcag ctcttcgccg aagacgttat gggtgcagga gggttctacc
     7621 atcagtatcg tcacgacggt atgccccacg atgcagcagt cgaaattgtc agtatgctcg
     7681 cctcaatcac ccatgagagc ctgcaatggg ctatgactaa cgttttgacc gtactgacac
     7741 agcgtaacct ttgggaaaca gtaaattacg agaactctat cgctatggtt gatgaggcac
     7801 tgcgcctata cacgcctacc gcagcgttag gacgcctcgc tactgttgat accaaaatag
     7861 gtggaacgtc cattcgtgcg ggggaattaa tcgtgtgttt acttcatgcc gcacaacacg
     7921 attccagaat gttcccaaac cacgatgagt ttacgctcgg caggccgcat gcgtcagaag
     7981 taacctttgg gatgggacct cacgcatgcc tcggattccc catcgcccgt cctctcatgg
     8041 gggcagttac ccataaaatc gcagaatctg cgtgtacttt acggcttggt gaaaatcctg
     8101 aaccactacc ggagatgatc aactctacgt ggatccaaat gccggtacac cttatacctt
     8161 caatctctgg ggagaatctt tatgcaggga tatgagcaat acagcgttat cgctgaggac
     8221 attcaccaaa attatagtga tgtgaaggtg cttaaaggcg tcaacctcgc ggtcgaaagg
     8281 ggagcagttc acggtattct cggacctaac ggcgcgggga aaagcacctt tgtagatttg
     8341 tgcaccggat cttctaaacc tacaagcggt acggtgcagg tcctcggcgt tgatccgcat
     8401 cgcaactctg cccttgtgcg ttcacatatg ggtattgtga tgcaggaagc ggcattcccg
     8461 actggactca aagtcaaaga tgctgtcacc tgctggcagc gttatatgtc tgcaacagaa
     8521 tacacagtgc ctgagttttt cgatcttgag aaactagcgg atcgcagaat ccatgagctt
     8581 tccggtggcg aaaggcgcaa acttgacctg tatctggcta tgatgggcaa tccttctctg
     8641 cttattcttg acgaacccac aactggactt gatccgttag ctcgtagaga tgtgtgggag
     8701 gttatacaga accttgccga aacaggtact accatattgc ttacttctca ctatcttgat
     8761 gaagtttcgg ctctttgcca gcaactttct attctcctta acgggcagat tgttgcgagc
     8821 ggaaccccag cgcatattgc taaagaatac agtcacacac ggcaaggctg ggtagaactc
     8881 tcggactgcc agaacgccca agctcttggc ggagaccttt cttcgcagag cgggtacaag
     8941 aatatacgtg ttcatgatgc cacggtttca ttcgatgtag agtccccaac agggttacaa
     9001 aacttatttg caacatccgc atatcgtgat gctgtccttg attttgcgct cagcgactat
     9061 tcacttgaaa acgcgtacgg cagcattgtg cgatctacgg atgccccaca gggtataggt
     9121 agtacccgca cagactagga aggccactta cgtgagtgcc acaatctcaa acttcacacg
     9181 aagtctgtat gcgcaaatag ccatgcagct gaccgtcttt atccgtaata tgcggagtgt
     9241 ttttttcact ttagccttcc ccattatgat gatcgtgctc ttcgccagtg gatcttcagg
     9301 acaggctaat attcccgctc agcagggagt tgatgtgaca atggcaagct ggactattgt
     9361 gggcttgtgc tgttatacgc ttctgatggg tacatttgtg cgtgtagcag gtgatatggc
     9421 ggcgcagcgc tcgacctctc tcctgaaacg tctgcgactt cggagcacat cggatgccgc
     9481 agtaatcgct ggttacattg tgactgcatc catcattgcc ctagcgtgta ctttaatcct
     9541 tattgtcttt ggcatggcgg tgtatcacct gcctatgcct aaaaatattc cattgacagt
     9601 attggttatt ctgctgacta cggtggtgct ctcgctcatc ggtgctgcgt acgcatcgtt
     9661 tattcccagt gcagaagcaa ctcagattat gctgctgccg cccgctctag ttttgatgtt
     9721 cctctcaggt atcttccaac ctgtatggac tatcccagct gggctacgag acttcgcagg
     9781 atggtttccc cttgtgcact taacggatgc attacgttcc gcgtggttcg ggctcgatgt
     9841 agcacacgcg caggtaagtg atactggatt aaccatccct tcaggaactc agttcatcag
     9901 tactcaaggg atgcttgtta tcggtttatg gtgtgcagtt tcacttattt ttgcgattac
     9961 taaattccgg tgggatcccc gacaacacta ggagagaact atgataaccg catcgttaga
    10021 taaccattct gagaccgctg agctatatcc ccaaggaact gaacgatatg taaggaaccc
    10081 acaattccac tttactcagc agacccggga aaatcgcacg acagttgttg cttcttcgcc
    10141 cgaaacaaca gtgctgcttg aagggcgtga ggctgaattt atcactgaag ttgacgggaa
    10201 aaccttggaa gatatgatgc gtttaccccg ctgggcagcg gatcttccac tcatgtttgc
    10261 tcttgcggct cagctgcagt atcgcgggct tattatgact gagactcaac tttcagacca
    10321 tactacgcag ggaaatattg agattattga cgttactcgt gcccgagttc ttgagtcttt
    10381 ctctgcctcg cctcaagacg gcatacgagt tattgatggg cacacagttc ctagggtgaa
    10441 ttcgggtttg ccagcggtga ttgtctgcga agatatgatt tctcccgctg ccgaaaagct
    10501 gtctcggaag tatgaagcgg cggggcatct gtactgccta gtgcaattac agggagcgga
    10561 tgctctcata agcccagtgc tggggacttc gtcgagcgta ccttatgacc agctcaagca
    10621 tagtcttcaa gttaacgcac agtatgctct ttcgggcggt aaacttctag acaatgttat
    10681 gggggcggcc tcagtaactc cgcgttccgt ggtgcgctca cttatctggt tggcaattca
    10741 gcgaatgaag acatcagagc ccgcagagcg tacagtctta cgttttaaaa acggtctctt
    10801 tgaaggggag cactacgtca tgacgggtgc caagactact aaagctcaac cgttgaacct
    10861 tgacgcgcag gctaaaaaaa ttgacctgag cttcaatccc gtcaacgacg ctggacgcgc
    10921 aaaatctacc cgagagacct gggaaaccta tcgacatctt gtatctgatg taacaggagt
    10981 cgtctcaagc cttaaacgtt tggtaccaga ggacgaagaa ctcttggtac acgtttatgg
    11041 ggcgggacat aactgggcac tcaatcacgg tagctctgaa gaattcacac gtagcttacg
    11101 cggtcgttct tcgggtaaag gaaccaccga tttaggtgcc cgagtatccg gtttggcaga
    11161 agctattgaa cgtcatagtg cgatctctga cggcactgaa gcccgtttac acaccagcta
    11221 taaagacttg ggggagcacg ctctagaccc tcgaaccctg acacagttct ctcaggatca
    11281 atacgagcaa cgggatgttc tcaaccaagt gaaggatcca tatcactggg ttccagaaaa
    11341 attcgatccc acagcagaga ttgattggat gcctgtttgg cggcccgcat gtgatgaaac
    11401 tgcctggatt cctgcagcat actcgttgtt catgtttgat catggagcga tgctgccagg
    11461 tgcaaaatgc ccgcttggac agaaaatgat gcgctcagat tcaaacggtc tcgcaagcgg
    11521 ttctacccca ggcgatgccg ccgcgcaggc tctgcttgaa cttattgagc gcgatgccgt
    11581 tgctatttgg tggtacaaca aaattccccg ccagataatg gcaccagagt ttacggatac
    11641 cccttttatt cagcgtaccc gagaatggct gcgaagtatt ggccgcaacc tagagattct
    11701 agatatcaca acagacatag gtattcctgt agctgccgct gtagccccta aacctgggga
    11761 tgcgtccgat cagatcattc tggggttcgg cgcgcatcct aaccctgaaa ttgccgcaac
    11821 ccgtgcagta acagaggctc tgcagtttat gtgtgccctg ccagcgcaat ttaggaccgc
    11881 agaaggtatg gatctagacc tccttaaaat ttcggtagat gatgctgcta gtcattggct
    11941 tcaaaacgct aaactagccg ataatcctca tcttgtacct gatccacagg cacttaacgt
    12001 agagcatgta ccgtggaagc aagccgaccc ccaacgtatt attgcgcgtc tggaagatgt
    12061 cggtttacct gtgtaccttc aagagcttac acgtccgtat attgggcttc ctgtagtacg
    12121 tgctctagtc ccggggctgc gtccgtggtg gaggcgctta gcaacgggac gactctacga
    12181 tgtgccggtt caatgcggat ggcttgccca gcccacccaa gaaactgacc tcaatccgac
    12241 ctccatgttc ttctagaggg agttaccccg tgacaaagac ccacctgaat ccacacaaaa
    12301 tacctttgat tcattgtgaa tatcagctga aacagacgca tcctcaaaac aatggaaagt
    12361 tcggaacttt agaagactgg gctcagaact tagacgtatc tgcacagcag gccgctctga
    12421 tattgactcg gcagagctcg tcaagaaacc ttatacaacg tcttatcaac cctgaaaccg
    12481 gagcaagcat agagatttct ggctttgagc tcctgctgac tgaagacgcg ctggaacctg
    12541 ttcttgacga ggcaaattat ccgcttggtc atactgactg cactcttacg ccgggcgttg
    12601 ttatttacgg gatgaatgga aatactcgcc ttgaaatagc gcatcggcct ttacgaataa
    12661 ctctcaatgc ccaagcctgg ttagatgcta tgacgggtgg cgtaacccat aaaattctgg
    12721 agtttatagg gatttttgcg cctgaagcac agcatcataa atatggtcct tgggactgtt
    12781 gggaacctca tgactatttt atgtaccgac gttccaggtt tgatacggca accggagggt
    12841 atggcgctac tcgaacacgt gagcacaaca caaccttgct caaaggcttg gcttctcttc
    12901 gacaagtttc cttccccaaa gttgattctc gccgccacca acttcttcta gatcaggcgc
    12961 ttctacaacg aacatcccgg cgcataccgc aaaaaccttc gttaagtctt gaatctctga
    13021 caacactgtt ggaagaaagc ctgcgtgaaa cttcccataa gagtgaaaat ataacacggc
    13081 tgccttttcc cagcggtggc gctcttcacg agctttaccc cttcatcatt gctcagaata
    13141 tcgaagggct ggaacaaggg ctatggtatg caaacctgca tactcgtcag tatgaacagg
    13201 ttgcggctgt tgaggagaaa actcagagcg cgtacatgcg tctattgcgt acctatgcaa
    13261 gttcggcaag gctaaagact gaagatgtac aggggcttgt tttattagct gctgattttg
    13321 accttgtgac ttcaacgtat gaaggagtcg catattctct taccctcaaa cacgtaggag
    13381 catggatgca aacggcctgc ctgcttgcgg aagaaatacc actcaacgta tgccctttag
    13441 gcggtggtga tgcccgcgcg tttgaaacac tcacaggcgt ttcatccgat agactggttc
    13501 ctgtgggcga gattctcgtg agttcctagc ttctacggta aggttttaca cccatgtttg
    13561 atacttacgg tatatggacc gctctggctt ggtgtgctct tgtgcttgct gcggtctgga
    13621 ttgggtacct cagaatccag cgtcctaccg tagggaagat ccatagtatt gtttctatca
    13681 ttattattat cttttcctta gtaggtattc taggcattaa gcaatctatg ctcccagtgg
    13741 ggattttatg ttgtgctata gcagttaccg gagtaaggaa tacaaaaata gcggctatta
    13801 caaccctggc agttgttgtg gctcttaact atttgcagac tttagaacct agctgggaga
    13861 tcaataccag ttcccatgat ccggctattg ttgccatcgt ggggtttctc ttcatgaatc
    13921 ttcggattag ccgagtatca caccggcggc ttcaagaaga actttatatt gctgaacaga
    13981 accaagagtt acgtgaacag aacctacagg cagagtttag gacccagatt gcggcgaacc
    14041 ttcatgatct tattgggcat gatttaacag ttattaatat tcgtttgcaa caattggtac
    14101 gtaccttaaa acctcttgat tcagatgtgg cacatgaagc gcgtgcgata cagaaaatga
    14161 cgcgttcttc tatagcccat ttacgcgacg ttgtagaagg ctttaataca gttgatttct
    14221 cgcatcaact caatgctgta ccgtcattac tgtcatatcg tggtattcaa gcccacatgg
    14281 atattcagca gaatgttctc aaggtcctta acccaagtac cctcacagca ctgtattggg
    14341 tgcttcttga agctatcacc aatgttctta aacatagcgg tgcaaaaaat tgctgggtga
    14401 gtctaaaaca acattcttcg ggtgactata tgcttattat cgcggatgat ggtataggac
    14461 tgaaggaaag ttctatgcgg aacaccggtg ccggtttagc agatatgaat acccgcattc
    14521 aacatatagg tggagagaca actcttggtg ccgcacctga gggtggaacc caagtcagag
    14581 ctaggatccc agcttctaac atcattactg gaggggcata aaattatgat tactgttctt
    14641 atagctgatg atcagacgat gttcggtagc gcgctcgcca gtctcattga tgaagaagaa
    14701 gatttggaaa ttgtgtgtgt ttgtcgagat ggacaggaag ctctggatag tattgtcaca
    14761 tatattccaa atgtagcgct tcttgatatt gaaatgccaa aacttaacgg tctagatgtt
    14821 cttgatgaag ttcagaagca aggcataaac acgaaaatag ctattctgac aacttttcaa
    14881 tctcctggtt acgttcgtcg tgctcttgaa agcggtgctt gtgcttttat aacaaaagat
    14941 caagatgctg aagaagtatc aaacattatt cgggatatac attctggaaa ggtagtggtt
    15001 gattctgcac tgcttcttag tggtgctacg ctgccagcta atccactcaa acccagacat
    15061 caggatgttc taaaactgac tatggaagga aaaaccgtca atcaaattgc acgggaacta
    15121 tacctttctc acggtactgt gaagaattac ctatctgaag ccattcaact tcttcactgt
    15181 acttcacgtg tagaggccgc tcacacggcg cgtactaacg gctggatttg acctgacgac
    15241 gtataaggcg gcggtgggct tataaagagc cttttcagca gggaaagtag ggaaagttat
    15301 gaaaaagtta tgaatcagtc ggggtgaaaa gctcacgaat ctgttccgca tccactcggg
    15361 acgaggcgaa ggagccgtcg ttgacgaccg catcaaacag cgccgctttc gatgccttca
    15421 aatccatgac cttctcttca atggtgccct cagccaccag ccggtacacg tgcacatcgc
    15481 gttcctgccc cagcctatgg atgcggtcca ccgcctgctg ttcagccgcc gggttccacc
    15541 acggatccat gatgaaacag tgatctgcct ccgtcaggtt cagcccgaac ccgcccgcct
    15601 tgagcgaaat aaggaacacc ggcgccgcac cctcggcgaa atctttcaga acctgtgggc
    15661 ggttgcgggt cgtgccgtcc aagtacagat agtcgatgcc ttcagcctgc agccgttcag
    15721 caattgtgcg cagatacccc gtgaactggc tgaacaccag cacccggtgc ccgtcgccta
    15781 agagcgaggg cagatgctcc accaaatatt cgagcttggc ggaagccacc ccggcgtatt
    15841 cgtccgggtc gataagcgtg gcgtcaagcg ctagacgccg cagaagcgtg agcgactgga
    15901 aaatcgtgaa ccggttctta tccatatctt ctaaaagccc gagcaccttt tgccgctcgc
    15961 gctgcagatg catatcgtaa atatgtcgat gcgccgtcgt gagtggcacg tttacccgca
    16021 catcgttctt ttcggggaga tcggcggcga ccacatcctt cgtgcggcgc agcatcagag
    16081 gacgaacccg gcggcgtagc ttctcaataa cctgcgggtc ttcaccggac tcggcggggc
    16141 gcgcatatag gtcgcggaac atgcgcgccg aggggaacag cccatccgcc acaatcacca
    16201 agagcgccca aagctccatg aggttgttct ccattggggt gcccgtaatg gcgagtttta
    16261 cctgcgcgtt tagggcacgt gccaccttcc atgcgcgagt tttcgtgttc ttcacgaact
    16321 gcgcttcgtc taaaatcaac gcaccccacc ctgcatgcgg ggaagcaccg ttctctgtgt
    16381 ttttgggaac atggttaccg aattcggtgt atccatcctc gtcgaggcgg aacagcgcat
    16441 agcttgtgag caccagatgc gcaccctgta ccagctccgc gatgctcttg ccgcttttgc
    16501 ccgtagactc ggtgatagtc accaccttcg cacccggcac gaatcgtgcg gcctcctgcg
    16561 cccagttacc caccacggat gttggcgcaa ccacgaggaa aggctcaaac tcggtgtgat
    16621 cggcgcgttg ctcatgctcg gcgatcgctt gggcaagcag agcgagcacc tgcacggttt
    16681 tacccaaacc catatcgtcg gcaagaatcc cgcccagccg gtgctgcctc aagaacgcga
    16741 gccagcggaa accctcaagc tgataaggtc gcagaactgc ggtaagaccc gggggagagg
    16801 gcaagtgatt cgccgaaaat acgccggaag aaacagataa agaatcggaa tgttcgttct
    16861 ctaaaacttc ttcggaaccg gcagtctcac ccgcccggtc agcggcctcc acgagggcga
    16921 gcagactctt aacctgcgca tcccaagaag ccacggtttc cacactcgaa gcgagcgatt
    16981 ccagttcaga aaacagcccc gcctgatgcc ggttaatgcg cagctcacca ccggtctcgt
    17041 tgagtgtgcg agcctcctca atgagggttc tcaacgccga aaactccggg cgattgagtg
    17101 aaaaataggt gccgttaccc agcagaatac ggtcttgatt ccgatcgagc gcctcaaaaa
    17161 cctgggcgaa aggcacagtc cagttattga ccttaatagc gatacccagc ccgaaccagt
    17221 cacgcgaatt accctcggtc accttgacct caatcatggc gtcggttgcc tcggtaaact
    17281 caggcacgga accgagcagt cgcacgcgaa ccccggaaat acaccgcagg gcgggcaaca
    17341 catgggcgag aatatcgcgg gtttcccatc cctgagagcg gcgttcaccg aacccgcctg
    17401 ccaacaccgg gttggatgcg gttgccgacc gtactgcgcg cagcacccgc gcctcaaaac
    17461 gttcgtcgcg ttctgtgccc aagcccagcg ccggcaggcg gcgaaccccc gagtccgtgc
    17521 cttcttcatc gagtgggttc ttcgggtatt cccaatacca attcaggagt gcgtcatgcg
    17581 aaatctcatc atcaaaatgc gcctcaaaca ccaaataggg cgaacgaacc ttcggcagcg
    17641 ccaaagccgg gtctggggta aggaatggga cggcccgcgt gagggtgggc aagaactcgc
    17701 ggtgaaaagc ctcgcgctcg cccgccggaa tacgcatttc gccgcgagat accaacgatt
    17761 ctgcgactgc gtccaaaggc tcggcaagcg gaataaacgc caggttaaga ccttccggca
    17821 ggtctggaat agtcggcatc gcggcgtttt cgagtgaaag ctcgggaatg agcccgcccg
    17881 tctgcgtttc agaattttcg ttttcgcccg cgctctcctc cgcctgctgc gaagattgag
    17941 cctgaaaaac atcgcgatgc ggcgcgtcta aggcgccctt gcgcgtgctc ttccaatgca
    18001 ctcgatgcgc ctgttcctcg taaatacgct gcacaagaga accgagcgcg aaaacccccg
    18061 agcgtggcga gccgatgggg tggcgtgccc ggcatcaaac cagagctgcc gcacccggtt
    18121 atcttcgcgg gtttcccacc ccaaggcggc atgaagagcc aagtcagggg cggaatcttc
    18181 gctcatggca gcctctgcgt tctgtcggga ctcggcctca acagctccgg catgcaccct
    18241 cacctgggcg ggtggcagaa ccgccgtagt cacctcaaac ccttcgagaa gaatcggcag
    18301 gccaatctgc tctgcgcgcg ctagaacatc ccacagcagc gtggaattcg tggcggtgag
    18361 cgagatccag tcccgatgcg aagagtacat attctgccac gggcgcgcga tagcgtatat
    18421 ttcagcgaag aaccgttcgt gctcggggta cacttcgtga cgaccgaccg gcccaccaac
    18481 gctggacgcg aaggtctccc agctgagtcc gcccttgatc cagcgcccgg ttttggactg
    18541 catcagcggt cgcgccagca ggttgatagg cggggttgca ccgggaatat tgcgcccgcg
    18601 cgcatatgaa cccgaaatgc tgaaggaaag gtcgagcgcc cccggaaccc gtgccgaatc
    18661 aataccggat gcttcgcccc gggcagcgag aacttgcgcc atatcgcgcc gccacaccga
    18721 aattttcgag ggcgaagaat gcgtattctc gtggtcgttc agggggagag gtttgggatc
    18781 ggtggtgagc gagcttgccg aacgaatcgc cccggatgcg cgcaacgccg ccaggggatc
    18841 gtcggctgcc tccgcaacct gtcgcgcggt atcttctggg ctctccgggt tcatagactg
    18901 gcggatgcgg ccgccgggcg tattgtcgag ggctttccgc gcggttttgg cacggtcgag
    18961 tgcagtgagc atgagggcga cggcgtgctt gcagtcggcg gcgaccgggc atgtgcatcg
    19021 tgcgttgaaa agattggaat cggcgtccga acccgggaag aagcgaatac ctacctcata
    19081 ggggataggg gtactcccgt tcaccagacc ttccagcgta ttttcgtctt cgtcgtaggt
    19141 gtatcgcacc acttcacgct gacgggcata agcaagcccg cgctggtatg ccttatgccc
    19201 cgcctgccga ataatctgcg caacggtgac ggggatatcg gggaaagggt ttggcgcgct
    19261 caccgttcca ttatctcaag ggtgtcaaag aatcgcgcgg taattcgtta tgaggtctgt
    19321 ccatgatgcg ctgagcgttt tttacatgta tttttgatgg atattgtgaa gaacataata
    19381 aaagtgataa tgccggtgag gaagccaacg cataagacac tcatggcgag ggtagcggct
    19441 gcctgtgtga gaggactcga ccccttgggc tggacgcccc tccactcgaa ggcatggtac
    19501 tcaacgactg atcccccgcc ggctaggatg aacaatccaa taccgagaat gaggagtagt
    19561 gcagctattg ccccgaccat acgtgcagtt ttcatgcttt ccccttgagt aactgacttt
    19621 atggattcat ctggtcccgt tcttttgcca agggtgtttt attctgctca acatgcttat
    19681 tttgtgcctt gcgtgccttc ttggtcgccg ttgtgaagag cagaataaag gtgataatgc
    19741 cggtgaggaa accaatgcct aggaaccata ggctcagatt attagtcgcc atgacgagcg
    19801 gacttgctcc tgcgggatcg acacccctcc actcgaaggc gtggtattcc acgagtgaac
    19861 cccagccggc taggatgagc aatccaaacc cgataaccag aagtactgcg gctactgctc
    19921 caactatgta gatagctttt ttcatgagcg ctccttagat actggctcta taaatcgatc
    19981 tggttctgac cttcttccaa gaggttttga acctgtacag gatgcttttt gtgcgtcttg
    20041 cgggagttcc tgaccgccgt ggtgaagaac ggaatcaagg cgataaagcc agtaagaaag
    20101 ccggtgccta agaaccagta gctgaggttg ccggttgctc gcgttagggg acttgctcct
    20161 ttatgctgta cacccctcca ttcgagggca tgatactcca cgagtgagcc ccagcctgcc
    20221 aggatgaaca agccaaaccc aatgatcaga aaaattgcgg ccactatccc catgatctgt
    20281 acagtctttt tcacagttat cactctttct ttccggaagc gtaaagcagg cgtgacatgg
    20341 tgatatatca gaggcaagat aaatttctgt acattaccca gtgtgccgtg attcttctcg
    20401 aatgtgtaga cctgctctga agacccaaaa cttcacacta cgccgccatg aggcggctat
    20461 atacaggtat gcattcataa tcgcgttatg taaatcacaa gagtttgacg ggttcgcacg
    20521 tttacagatt cctgaaagct gttgtaacct ggattcagct tcaagagttt cgactgataa
    20581 gctccgacta tggtcgaacg ccaaccccat gttcacgggt ggctcggatg acgaagcggt
    20641 ttgtattcgc cgcctcaggt ggcacttggt acaggcaaga gcaacgcgaa aggaacgcgc
    20701 attcggcgca tggttgtcaa tgtacaacag ctcttcatct ccagcatccc cccttactcc
    20761 tgcacgctct tatcaggaaa atctgcgtgc cgcatctgtg cccgcacgcg gcggttacca
    20821 ggcagtaagt attcaggact acgcacgtat ttcttctaag cgcgacgaat tcctcaattt
    20881 tctgcttctt cccaaccccg agggtattcc tgccgtcgaa tatgccggtc tgcgcgtagc
    20941 ataggggtat gagcgcctca ggactgcttc tcgactcgga tgttctcgcc gagattcgta
    21001 aagctacacc agattccaaa gttgttgcct ttctgcgccg ccgcgcctat aaacacctct
    21061 acatttcggt attgagtgta ggcgagctca aaggactcta cccctaccca gagaccgacc
    21121 gttggattgc cgaacttctc gacagattcg ccgaccacat catcaacgtg gatgcccgcg
    21181 taagcctcga atgggcggga cgcagcgccc cgcgcggcat ccacagtcac ggacgtaaag
    21241 atgccgagcc cctgcccacc gccgccctcg aaggtctgat ggcggcgagc gcccaagctc
    21301 acgacctcga aattgtttct tcaaaggctg aggtgtaccg gtcctggggc gtgcccgcgg
    21361 tgaatccgtg gattgaagac taaatcttcc gcacagtatt ttcaccgtaa gcgccgggga
    21421 agtacctgcg tgttcgagaa agccgtgaga aatgctcggc acagttagct gtacgcgctg
    21481 ccgcatcggt gagagcgcat cagtaacgtt cgtgtaaccc ctatgttcac ggtgagcggt
    21541 taacgaaggt tagccgccat ttaaccggaa ctatttcccc gaaagcccag caggctcaca
    21601 cgcgctgaca ggtttcatgg catgatggaa gaacgatgaa aagtagctct tctacatccc
    21661 ggtattctgc ccctatgcca ctctggctgc agggcatcgt tgaattagtt tttaccgccg
    21721 cgctttcttt cgggcttgtg ctcgttctgc tcatggcggt gtggtttacc aacggtttta
    21781 accgcatgga ttttcccgca ctcgcaactc ttgcctccca cctgtggctg ctcatgcacg
    21841 gtgtgccgct gaatattccg aatgctttcg gcattattct gccgcacggc atgctcacac
    21901 tggtacccat ggggctgagc attattccgg tgctcttatg ctttaggtct gggcgaaaac
    21961 tggcgcgcgc atcctatgag ggggaattct tcaagcccgt actattaggg tgcgctgcct
    22021 acggtatttt tgctgccgtc gcctttgcgt gggcgagtac cgaacggcat ctgctgggta
    22081 ttgttggtgc ggcgttgatt ccgcagatag tggtgctggt cgggttgatc tggggcggct
    22141 actatgaatc gcgttcgctc gcccgtatgg tgggcgtgaa caccgccgaa cagatttcgc
    22201 agatgagcca gtactcgcga tgggcgagct cctatgtgtg gtcgattgtg cgtgcctcca
    22261 tggtggcgat tttctcgctc attatgggcg gtgctctggt gctggtggtt gccatgatga
    22321 tgcgttggtc gcaaatcgca acaatttacc aggaacttca cgccgggccg gtgggggcgc
    22381 tcgccgtgac cctgctgcag cttggttacc ttccgaactt ggtgatctac gcgatgtcgt
    22441 ggactaccgg cgccgggttt gcgttcggcg tggatacaca tgtgggttgg tcgcagacga
    22501 cgatgggcga tcttccgctc tttccggtgc tgggtgctat ccctgagagc ctgggctgga
    22561 tagggtatgc gggtctggcg gtttcgctgg gcgccggagc cgttgccggt tggtggttct
    22621 tgcgtgaagg tgaagaccac gtggaggagt ggatcaccat gaaggtacgt taccgggtga
    22681 ttgcgctgcc gctttcttcg ctcgtgttgg gttcgctggt gggtgtgctc tgcggcgtgt
    22741 gggcttatat tttgggttgg atttccagcg gatcgttggg tgtggggcgt tttaccgagg
    22801 taggcgcatc gcccgcagct ttcgccgtgg cgaccgcaat aaccctgggt gcgggtaccg
    22861 cgttgggtaa cctgctgtgc catgtgcttc ttcccgacag cagtcgtgag ctgccgcgtt
    22921 ttgccgatga acgtcccaat ctgggcagtc gcatgagcga gatgctgcag cagcgtcgcg
    22981 cggcgcgggc agagcgtgaa cagctcagga acgatgagca ggaacgcgag gcacaagaac
    23041 gtgaagagca ggcgcgtgag cgggctcagc agcggcgcga acgagtcaaa caggtgcacg
    23101 cccgccgtgc agaactcaat aaatttgctg agcaagaaga agcacagcga gcgcatagtt
    23161 taggtatcaa aacggagcaa gaatccttgc gtgaggatag ttctgccgaa gctgcagact
    23221 cgaaggatgc ggcatctgac gaacaaacca tcgagctgtc gggagcggat gaacccaccg
    23281 tggaacttga tacctctgag aaatccggtg ggggtaccga ggacgcgccg cgcacggtca
    23341 agcccggtaa gcgtgagaaa gccccgggga agccggtctt taaccgcgtt ccgcgccccg
    23401 aaacctcggg taatggcggt gatactaagg tcgagcggga aacacgagag cagagcgctc
    23461 gtacagggga gtctgggccg cagaaagccc cttcgtcagt ggagtttcac gagtccgggt
    23521 ataaacgtt
//
