Select genomic region:
Overview
15.1
15.2
16.1
18.1
18.2
19.1

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_KV804811.1 (Rothia sp. HMSC065G12)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 15.1 | butyrolactone | 31,697 | 47,557 | Low | branched-chain fatty acids | other:other
Region 15.2 | azole-containing-RiPP | 72,335 | 94,579 |  |

NZ_KV804813.1 (Rothia sp. HMSC065G12)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 16.1 | azole-containing-RiPP | 62,824 | 86,352 |

NZ_KV804815.1 (Rothia sp. HMSC065G12)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 18.1 | terpene-precursor | 42,608 | 63,750 |
Region 18.2 | NRPS | 657,923 | 702,155 | High | enterobactin | NRPS:Type I

NZ_KV804818.1 (Rothia sp. HMSC065G12)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 19.1 | lanthipeptide-class-ii,linaridin | 81,736 | 131,908 |

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 15.1 | butyrolactone | 31,697 | 47,557 | Low | branched-chain fatty acids | other:other
Region 15.2 | azole-containing-RiPP | 72,335 | 94,579 |  |
Region 16.1 | azole-containing-RiPP | 62,824 | 86,352 |
Region 18.1 | terpene-precursor | 42,608 | 63,750 |
Region 18.2 | NRPS | 657,923 | 702,155 | High | enterobactin | NRPS:Type I
Region 19.1 | lanthipeptide-class-ii,linaridin | 81,736 | 131,908 |

No secondary metabolite regions were found in these records:
  NZ_KV804792.1 (Rothia sp. HMSC065G12)
  NZ_KV804794.1 (Rothia sp. HMSC065G12)
  NZ_KV804795.1 (Rothia sp. HMSC065G12)
  NZ_KV804796.1 (Rothia sp. HMSC065G12)
  NZ_KV804797.1 (Rothia sp. HMSC065G12)
  NZ_KV804799.1 (Rothia sp. HMSC065G12)
  NZ_KV804800.1 (Rothia sp. HMSC065G12)
  NZ_KV804801.1 (Rothia sp. HMSC065G12)
  NZ_KV804803.1 (Rothia sp. HMSC065G12)
  NZ_KV804804.1 (Rothia sp. HMSC065G12)
  NZ_KV804805.1 (Rothia sp. HMSC065G12)
  NZ_KV804806.1 (Rothia sp. HMSC065G12)
  NZ_KV804807.1 (Rothia sp. HMSC065G12)
  NZ_KV804808.1 (Rothia sp. HMSC065G12)
  NZ_KV804814.1 (Rothia sp. HMSC065G12)
  NZ_KV804819.1 (Rothia sp. HMSC065G12)
  NZ_KV804820.1 (Rothia sp. HMSC065G12)

Compact view
NZ_KV804811.1 - Region 1 - butyrolactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 31,697 - 47,557 nt. (total: 15,861 nt) Show pHMM detection rules used
butyrolactone: AfsA

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase
HMPREF2804_RS02695: short-chain dehydrogenase/reductase SDR

smcogs
  SMCOG1001: short-chain dehydrogenase/reductase SDR

Ligases: ligase synthase
HMPREF2804_RS02665: 1-deoxy-D-xylulose-5-phosphate synthase

smcogs
  SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase

HMPREF2804_RS02675: 3-oxoacyl-(acyl carrier protein) synthase III

smcogs
  SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III

HMPREF2804_RS02685: Beta-ketoacyl synthase

smcogs
  SMCOG1022: Beta-ketoacyl synthase

HMPREF2804_RS02725: AMP-dependent synthetase and ligase

smcogs
  SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | butyrolactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001535.3 |  | 0.70 | other (other) | branched-chain fatty acids | Streptomyces filamentosus
BGC0001534.3 |  | 0.63 | other (other) | branched-chain fatty acids | Streptomyces filamentosus
BGC0001164.3 |  | 0.58 | PKS | 1-heptadecene | Cyanothece sp. PCC 7822
BGC0001641.4 |  | 0.58 | NRPS | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0002711.2 |  | 0.54 | PKS | nostovalerolactone, 9-dehydronostovalerolactone | Nostoc punctiforme PCC 73102
BGC0001987.2 |  | 0.51 | PKS | koreenceine A, koreenceine B, koreenceine C, koreenceine D | Pseudomonas koreensis
BGC0001197.5 |  | 0.50 | PKS | frankiamicin | Frankia sp. EAN1pec
BGC0000866.5 |  | 0.50 | other (other) | polyhydroxyalkanoate | Burkholderia sp. DSM 9242
BGC0001723.5 |  | 0.49 | PKS | oviedomycin | Streptomyces antibioticus
BGC0000234.5 |  | 0.48 | PKS | jadomycin | Streptomyces venezuelae ATCC 10712

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001535.3 |  | 0.70 | other (other) | branched-chain fatty acids | Streptomyces filamentosus
BGC0001534.3 |  | 0.63 | other (other) | branched-chain fatty acids | Streptomyces filamentosus
BGC0001164.3 |  | 0.58 | PKS | 1-heptadecene | Cyanothece sp. PCC 7822
BGC0001641.4 |  | 0.58 | NRPS | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0002711.2 |  | 0.54 | PKS | nostovalerolactone, 9-dehydronostovalerolactone | Nostoc punctiforme PCC 73102
BGC0001987.2 |  | 0.51 | PKS | koreenceine A, koreenceine B, koreenceine C, koreenceine D | Pseudomonas koreensis
BGC0001197.5 |  | 0.50 | PKS | frankiamicin | Frankia sp. EAN1pec
BGC0000866.5 |  | 0.50 | other (other) | polyhydroxyalkanoate | Burkholderia sp. DSM 9242
BGC0001723.5 |  | 0.49 | PKS | oviedomycin | Streptomyces antibioticus
BGC0000234.5 |  | 0.48 | PKS | jadomycin | Streptomyces venezuelae ATCC 10712

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Location:
Identifier
Identity
Coverage
Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 23.70 out of 29.25
Confidence: medium
Additional weak hits (9):
AfsQ1
Description: Two-component system AfsQ1-Q2, activator of antibiotic production
Species: Streptomyces coelicolor
Score: 16.94 out of 19.52
Confidence: weak
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 18.66 out of 29.38
Confidence: weak
HexR
Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 21.08 out of 31.73
Confidence: weak
PerR
Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 17.37 out of 28.14
Confidence: weak
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 17.88 out of 27.78
Confidence: weak
HipB
Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 20.42 out of 33.73
Confidence: weak
HexR
Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 19.83 out of 31.73
Confidence: weak
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 19.18 out of 29.38
Confidence: weak
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 18.10 out of 26.06
Confidence: weak
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
SypG | Regulator of biofilm formation and host colonization

NZ_KV804811.1 - Region 2 - azole-containing-RiPP
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 72,335 - 94,579 nt. (total: 22,245 nt) Show pHMM detection rules used
azole-containing-RiPP: ((YcaO or TIGR03604) and (((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or thiostrepton or TIGR03602)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Azole RiPPs
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase synthase
HMPREF2804_RS02840: crotonyl-CoA reductase / alcohol dehydrogenase

smcogs
  SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase

HMPREF2804_RS02940: riboflavin biosynthesis protein RibD

smcogs
  SMCOG1240: riboflavin biosynthesis protein RibD

Hydrolases: synthase
HMPREF2804_RS02940: riboflavin biosynthesis protein RibD

smcogs
  SMCOG1240: riboflavin biosynthesis protein RibD

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | azole-containing-RiPP | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001174.4 |  | 0.51 | ribosomal | corynazolicin | Corynebacterium urealyticum DSM 7111
BGC0000569.5 |  | 0.50 | ribosomal | plantazolicin | Bacillus velezensis FZB42
BGC0001173.5 |  | 0.50 | ribosomal | plantazolicin | Bacillus pumilus ATCC 7061
BGC0002144.3 |  | 0.47 | ribosomal | phazolicin | Rhizobium sp. Pop5
BGC0000568.5 |  | 0.47 | ribosomal | microcin B17 | Escherichia coli
BGC0002013.4 |  | 0.46 | ribosomal | curacozole | Streptomyces curacoi
BGC0002115.3 |  | 0.43 | ribosomal | streptamidine | Streptomyces albidoflavus J1074
BGC0000560.5 |  | 0.40 | ribosomal | subtilomycin | Bacillus subtilis
BGC0002515.2 |  | 0.39 | PKS | solanapyrone A | Ascochyta rabiei
BGC0002701.2 |  | 0.39 | ribosomal | paenithipeptin | Paenibacillus thiaminolyticus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001174.4 |  | 0.51 | ribosomal | corynazolicin | Corynebacterium urealyticum DSM 7111
BGC0000569.5 |  | 0.50 | ribosomal | plantazolicin | Bacillus velezensis FZB42
BGC0001173.5 |  | 0.50 | ribosomal | plantazolicin | Bacillus pumilus ATCC 7061
BGC0002144.3 |  | 0.47 | ribosomal | phazolicin | Rhizobium sp. Pop5
BGC0000568.5 |  | 0.47 | ribosomal | microcin B17 | Escherichia coli
BGC0002013.4 |  | 0.46 | ribosomal | curacozole | Streptomyces curacoi
BGC0002115.3 |  | 0.43 | ribosomal | streptamidine | Streptomyces albidoflavus J1074
BGC0000560.5 |  | 0.40 | ribosomal | subtilomycin | Bacillus subtilis
BGC0002515.2 |  | 0.39 | PKS | solanapyrone A | Ascochyta rabiei
BGC0002701.2 |  | 0.39 | ribosomal | paenithipeptin | Paenibacillus thiaminolyticus

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.93 out of 30.25
Confidence: medium
Additional weak hits (8):
ArcA
Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 18.15 out of 21.55
Confidence: weak
NtrC
Description: Nitrogen regulatory protein C
Species: Pseudomonas putida KT2440
Score: 21.49 out of 29.72
Confidence: weak
DosR
Description: Hypoxia stress response regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 21.60 out of 29.51
Confidence: weak
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.44 out of 26.06
Confidence: weak
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 21.48 out of 30.25
Confidence: weak
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.52 out of 26.06
Confidence: weak
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 19.66 out of 26.06
Confidence: weak
ZuR variant 2
Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 21.52 out of 33.14
Confidence: weak
(Thi)azol(in)e containing peptide predictions
Lists the possible core peptides for each biosynthetic enzyme. Predicted tail sequences are also shown, if present.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.
No core peptides found.
TFBS Finder
Azole RiPPs
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
ColR | Phenol-responsive regulator

Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists its possible molecular weights and the scores for cleavage site prediction and RODEO. If relevant, other features, such as macrocycle and amidation, will also be listed.
No core peptides found.
NZ_KV804813.1 - Region 1 - azole-containing-RiPP
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 62,824 - 86,352 nt. (total: 23,529 nt) Show pHMM detection rules used
azole-containing-RiPP: ((YcaO or TIGR03604) and (((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or thiostrepton or TIGR03602)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Azole RiPPs
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: oxidoreductase oxygenase
HMPREF2804_RS03330: aldo/keto reductase family oxidoreductase

smcogs
  SMCOG1039: aldo/keto reductase family oxidoreductase

HMPREF2804_RS03340: cytochrome P450

smcogs
  SMCOG1007: cytochrome P450

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | azole-containing-RiPP | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002584.2 |  | 0.44 | ribosomal | azolemycin B, azolemycin A, azolemycin D, azolemycin C | Streptomyces sp. FXJ1.264
BGC0000528.5 |  | 0.44 | ribosomal | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0001849.4 |  | 0.44 | ribosomal | thiovarsolin A, thiovarsolin B, thiovarsolin C, thiovarsolin D | Streptomyces varsoviensis
BGC0001226.4 |  | 0.42 | ribosomal | streptocollin | Streptomyces collinus Tu 365
BGC0000563.4 |  | 0.42 | ribosomal | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0002707.2 |  | 0.42 | terpene | (+)-δ-cadinol | Coniophora puteana RWD-64-598 SS2
BGC0002551.2 |  | 0.41 | other (other), ribosomal, terpene | muscoride A, muscoride B | Nostoc sp. UHCC-0398
BGC0000569.5 |  | 0.41 | ribosomal | plantazolicin | Bacillus velezensis FZB42
BGC0001173.5 |  | 0.41 | ribosomal | plantazolicin | Bacillus pumilus ATCC 7061
BGC0002485.2 |  | 0.41 | other (other), ribosomal | muscoride A, muscoride B | Desmonostoc sp. PCC 7906

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002584.2 |  | 0.44 | ribosomal | azolemycin B, azolemycin A, azolemycin D, azolemycin C | Streptomyces sp. FXJ1.264
BGC0000528.5 |  | 0.44 | ribosomal | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0001849.4 |  | 0.44 | ribosomal | thiovarsolin A, thiovarsolin B, thiovarsolin C, thiovarsolin D | Streptomyces varsoviensis
BGC0001226.4 |  | 0.42 | ribosomal | streptocollin | Streptomyces collinus Tu 365
BGC0000563.4 |  | 0.42 | ribosomal | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0002707.2 |  | 0.42 | terpene | (+)-δ-cadinol | Coniophora puteana RWD-64-598 SS2
BGC0002551.2 |  | 0.41 | other (other), ribosomal, terpene | muscoride A, muscoride B | Nostoc sp. UHCC-0398
BGC0000569.5 |  | 0.41 | ribosomal | plantazolicin | Bacillus velezensis FZB42
BGC0001173.5 |  | 0.41 | ribosomal | plantazolicin | Bacillus pumilus ATCC 7061
BGC0002485.2 |  | 0.41 | other (other), ribosomal | muscoride A, muscoride B | Desmonostoc sp. PCC 7906

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 20.87 out of 27.78
Confidence: medium
Additional weak hits (7):
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 20.53 out of 30.25
Confidence: weak
LuxO
Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 19.60 out of 26.12
Confidence: weak
HipB
Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 21.41 out of 33.73
Confidence: weak
NrtR
Description: NAD synthesis repressor
Species: Streptomyces coelicolor
Score: 22.31 out of 35.63
Confidence: weak
ZuR variant 2
Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 22.33 out of 33.14
Confidence: weak
CelR
Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 20.92 out of 30.11
Confidence: weak
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 20.24 out of 29.25
Confidence: weak
(Thi)azol(in)e containing peptide predictions
Lists the possible core peptides for each biosynthetic enzyme. Predicted tail sequences are also shown, if present.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.
No core peptides found.
TFBS Finder
Azole RiPPs
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria

Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists its possible molecular weights and the scores for cleavage site prediction and RODEO. If relevant, other features, such as macrocycle and amidation, will also be listed.
No core peptides found.
NZ_KV804815.1 - Region 1 - terpene-precursor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 42,608 - 63,750 nt. (total: 21,143 nt) Show pHMM detection rules used
terpene-precursor: (PT_FPPS_like and not PT_HPP)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: oxidoreductase
HMPREF2804_RS05500: pyridine nucleotide-disulfide oxidoreductase

smcogs
  SMCOG1175: pyridine nucleotide-disulfide oxidoreductase

Transferases: acyltransferase
HMPREF2804_RS05515: acyltransferase

smcogs
  SMCOG1141: acyltransferase

Ligases: ligase synthetase
HMPREF2804_RS05505: AMP-dependent synthetase and ligase

smcogs
  SMCOG1002: AMP-dependent synthetase and ligase

HMPREF2804_RS05535: Polyprenyl synthetase

smcogs
  SMCOG1182: Polyprenyl synthetase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene-precursor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002193.2 |  | 0.56 | other (other) | phenguignardic acid | Aspergillus terreus NIH2624
BGC0000677.5 |  | 0.42 | terpene | cyclooctatin | Streptomyces melanosporofaciens
BGC0002561.3 |  | 0.40 | other (other) | phenazine SA, phenazine SB, phenazine SC | Streptomyces sp.
BGC0000649.3 |  | 0.40 | terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000597.4 |  | 0.40 | ribosomal | SWA-2138 | Streptomyces sp. e14
BGC0001910.4 |  | 0.39 | terpene | cyslabdan A, cyslabdan B, cyslabdan C | Streptomyces cyslabdanicus
BGC0000595.3 |  | 0.39 | ribosomal | SCO-2138 | Streptomyces coelicolor A3(2)
BGC0001456.3 |  | 0.38 | terpene | isorenieratene | Streptomyces argillaceus
BGC0000664.5 |  | 0.38 | terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001911.3 |  | 0.38 | terpene | raimonol | Streptomyces anulatus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002193.2 |  | 0.56 | other (other) | phenguignardic acid | Aspergillus terreus NIH2624
BGC0000677.5 |  | 0.42 | terpene | cyclooctatin | Streptomyces melanosporofaciens
BGC0002561.3 |  | 0.40 | other (other) | phenazine SA, phenazine SB, phenazine SC | Streptomyces sp.
BGC0000649.3 |  | 0.40 | terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000597.4 |  | 0.40 | ribosomal | SWA-2138 | Streptomyces sp. e14
BGC0001910.4 |  | 0.39 | terpene | cyslabdan A, cyslabdan B, cyslabdan C | Streptomyces cyslabdanicus
BGC0000595.3 |  | 0.39 | ribosomal | SCO-2138 | Streptomyces coelicolor A3(2)
BGC0001456.3 |  | 0.38 | terpene | isorenieratene | Streptomyces argillaceus
BGC0000664.5 |  | 0.38 | terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001911.3 |  | 0.38 | terpene | raimonol | Streptomyces anulatus

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
sesquiterpene precursor |  | FPP | C15 | acyclic | PP
diterpene precursor |  | GGPP | C20 | acyclic | PP
sesterterpene precursor |  | GFPP | C25 | acyclic | PP
triterpene precursor |  | HPP | C30 | acyclic | PP

Genes with terpene domains:
HMPREF2804_RS05535: PT_FPPS_like
Domain 1 (58 - 371): Prenyltransferase; Farnesyl diphosphate synthase like
Subtype: unknown

Reactions:
  IPP, DMAPP → FPP
  IPP, DMAPP → GGPP
  IPP, DMAPP → GFPP
  IPP, DMAPP → HPP

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
No hits above weak threshold.
Weak hits (3):
PerR
Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 20.40 out of 28.14
Confidence: weak
RicR
Description: Copper-responsive regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 21.87 out of 32.93
Confidence: weak
HgtR
Description: Hydrogen-dependent regulator
Species: Geobacter sulfurreducens PCA
Score: 24.07 out of 36.54
Confidence: weak
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
DMAPP | Dimethylallyl diphosphate
FPP | Farnesyl diphosphate
GFPP | Geranylfarnesyl diphosphate
GGPP | Geranylgeranyl diphosphate
HPP | Hexaprenyl diphosphate
IPP | Isopentenyl diphosphate
PP | Diphosphate

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---

NZ_KV804815.1 - Region 2 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 657,923 - 702,155 nt. (total: 44,233 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
NRPS/PKS modules
NRPS/PKS domains
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase
HMPREF2804_RS08060: 3-hydroxyisobutyrate dehydrogenase

smcogs
  SMCOG1100: 3-hydroxyisobutyrate dehydrogenase

Transferases: formyltransferase transketolase
HMPREF2804_RS08070: transketolase

smcogs
  SMCOG1204: transketolase

HMPREF2804_RS08155: methionyl-tRNA formyltransferase

smcogs
  SMCOG1228: methionyl-tRNA formyltransferase

Hydrolases: deformylase esterase
HMPREF2804_RS08100: enterobactin/ferric enterobactin esterase

smcogs
  SMCOG1098: enterobactin/ferric enterobactin esterase

HMPREF2804_RS08160: peptide deformylase

smcogs
  SMCOG1275: peptide deformylase

Ligases: ligase synthase
HMPREF2804_RS08050: cysteine synthase

smcogs
  SMCOG1081: cysteine synthase

HMPREF2804_RS08085: AMP-dependent synthetase and ligase

smcogs
  SMCOG1002: AMP-dependent synthetase and ligase

HMPREF2804_RS08095: AMP-dependent synthetase and ligase

smcogs
  SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002685.2 |  | 0.74 | NRPS | enterobactin | Rothia mucilaginosa ATCC 25296
BGC0001825.4 |  | 0.66 | NRPS | xenematide | Xenorhabdus nematophila AN6/1
BGC0001641.4 |  | 0.63 | NRPS | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0002135.2 |  | 0.63 | NRPS | bovienimide A | Xenorhabdus bovienii SS-2004
BGC0001261.3 |  | 0.63 | NRPS | AM-toxin | Alternaria alternata
BGC0000357.5 |  | 0.63 | NRPS | cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val) | Penicillium rubens Wisconsin 54-1255
BGC0001251.4 |  | 0.62 | NRPS | epichloenin A | Epichloe festucae
BGC0001250.4 |  | 0.62 | NRPS | epichloenin A | Epichloe festucae
BGC0001240.4 |  | 0.62 | NRPS | serinocyclin A, serinocyclin B | Metarhizium robertsii
BGC0000342.4 |  | 0.62 | NRPS | enniatin | Fusarium equiseti

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002685.2 |  | 0.74 | NRPS | enterobactin | Rothia mucilaginosa ATCC 25296
BGC0001825.4 |  | 0.66 | NRPS | xenematide | Xenorhabdus nematophila AN6/1
BGC0001641.4 |  | 0.63 | NRPS | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0002135.2 |  | 0.63 | NRPS | bovienimide A | Xenorhabdus bovienii SS-2004
BGC0001261.3 |  | 0.63 | NRPS | AM-toxin | Alternaria alternata
BGC0000357.5 |  | 0.63 | NRPS | cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val) | Penicillium rubens Wisconsin 54-1255
BGC0001251.4 |  | 0.62 | NRPS | epichloenin A | Epichloe festucae
BGC0001250.4 |  | 0.62 | NRPS | epichloenin A | Epichloe festucae
BGC0001240.4 |  | 0.62 | NRPS | serinocyclin A, serinocyclin B | Metarhizium robertsii
BGC0000342.4 |  | 0.62 | NRPS | enniatin | Fusarium equiseti

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 21.59 out of 27.78
Confidence: medium
NtrC
Description: Nitrogen regulatory protein C
Species: Pseudomonas putida KT2440
Score: 22.89 out of 29.72
Confidence: medium
IolR
Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.10 out of 23.79
Confidence: medium
Additional weak hits (13):
MexT
Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 18.12 out of 21.84
Confidence: weak
CopR
Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 21.31 out of 30.97
Confidence: weak
ArcA
Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 17.68 out of 21.55
Confidence: weak
LexA variant 2
Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 19.39 out of 24.78
Confidence: weak
HypR
Description: L-hydroxyproline utilization repressor
Species: Streptomyces coelicolor
Score: 18.79 out of 22.40
Confidence: weak
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 21.45 out of 29.25
Confidence: weak
DmdR1
Description: Iron(II)-dependent repressor
Species: Streptomyces coelicolor
Score: 23.42 out of 36.53
Confidence: weak
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 19.08 out of 26.06
Confidence: weak
MexT
Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 18.38 out of 21.84
Confidence: weak
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 20.00 out of 26.06
Confidence: weak
LuxO
Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 20.88 out of 26.12
Confidence: weak
NuR
Description: Nickel-responsive regulator
Species: Streptomyces coelicolor
Score: 22.10 out of 30.98
Confidence: weak
DmdR1
Description: Iron(II)-dependent repressor
Species: Streptomyces coelicolor
Score: 25.12 out of 36.53
Confidence: weak
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions.
Genes are shown in predicted order, and are only present when containing at least one complete module.
A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
NRPS/PKS products
NRPS/PKS substrates
TFBS Finder
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 657922 - 702155:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (Ser)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
HMPREF2804_RS08085: Ser
Search NORINE for peptide: strict or relaxed
AMP-binding (520..959): Ser
nrpys: Ser

SVM prediction details:
  Predicted physicochemical class:
    hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
  Large clusters prediction:
    Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
  Small clusters prediction:
    ser (Ser)
  Single AA prediction:
    ser (Ser)

Stachelhaus prediction details:
  Stachelhaus sequence:
    RWQTFDVHVWEWHFICSGELNLYGPTEAAVDVTF
  Nearest Stachelhaus code(s):
    Ser DVWHISLVDK (88% 8Å match)
  Stachelhaus code match:
    100% (strong)

HMPREF2804_RS08095: diOH-Bz
Search NORINE for peptide: strict or relaxed
AMP-binding (54..466): diOH-Bz
nrpys: diOH-Bz

SVM prediction details:
  Predicted physicochemical class:
    hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
  Large clusters prediction:
    Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
  Small clusters prediction:
    Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
  Single AA prediction:
    dhb (diOH-Bz)

Stachelhaus prediction details:
  Stachelhaus sequence:
    SGSLFTMSSPGGSLQVGGSQQVFGMAEGLVNYTR
  Nearest Stachelhaus code(s):
    diOH-Bz TMPSQGVVNK (94% 8Å match)
  Stachelhaus code match:
    100% (strong)

Link to PARAS substrate predictor
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
IolR | Regulator of the inositol catabolism
NtrC | Nitrogen regulatory protein C

NZ_KV804818.1 - Region 1 - lanthipeptide-class-ii,linaridin
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 81,736 - 131,908 nt. (total: 50,173 nt) Show pHMM detection rules used
lanthipeptide-class-ii: cds(LANC_like and DUF4135)
linaridin: (cypemycin or cypI)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Lanthipeptides
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase oxidoreductase oxygenase
HMPREF2804_RS09495: dehydrogenase

smcogs
  SMCOG1222: dehydrogenase

HMPREF2804_RS09510: cytochrome P450

smcogs
  SMCOG1007: cytochrome P450

HMPREF2804_RS09520: aldo/keto reductase family oxidoreductase

smcogs
  SMCOG1039: aldo/keto reductase family oxidoreductase

Lyases: cyclase
HMPREF2804_RS09425: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

HMPREF2804_RS09470: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

HMPREF2804_RS09490: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-ii | linaridin | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0001229.4 |  |  | 0.53 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0002110.3 |  |  | 0.46 | ribosomal | birimositide | Streptomyces rimosus subsp. rimosus WC-3908
BGC0000583.5 |  |  | 0.44 | ribosomal | grisemycin | Streptomyces griseus subsp. griseus NBRC 13350
BGC0002698.2 |  |  | 0.43 | ribosomal | phaeornamide | Pseudophaeobacter arcticus DSM 23566
BGC0002319.3 |  |  | 0.43 | ribosomal | salinipeptin A, salinipeptin B, salinipeptin C, salinipeptin D | Streptomyces sp.
BGC0000582.4 |  |  | 0.39 | ribosomal | cypemycin | Streptomyces sp. OH-4156
BGC0001555.4 |  |  | 0.39 | ribosomal | colicin V | Escherichia coli chi7122
BGC0001201.3 |  |  | 0.39 | terpene | eremophilene | Sorangium cellulosum So ce56
BGC0000497.3 |  |  | 0.38 | ribosomal | BHT-Aα, BHT-Aβ | Streptococcus ratti
BGC0000554.4 |  |  | 0.38 | ribosomal | SRO15-3108 | Streptomyces filamentosus NRRL 15998

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001229.4 |  | 0.61 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0002110.3 |  | 0.58 | ribosomal | birimositide | Streptomyces rimosus subsp. rimosus WC-3908
BGC0002698.2 |  | 0.57 | ribosomal | phaeornamide | Pseudophaeobacter arcticus DSM 23566
BGC0000583.5 |  | 0.55 | ribosomal | grisemycin | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000497.3 |  | 0.54 | ribosomal | BHT-Aα, BHT-Aβ | Streptococcus ratti
BGC0002319.3 |  | 0.54 | ribosomal | salinipeptin A, salinipeptin B, salinipeptin C, salinipeptin D | Streptomyces sp.
BGC0000623.3 |  | 0.53 | ribosomal | plantaricin W α, plantaricin W β | Lactobacillus plantarum
BGC0000582.4 |  | 0.52 | ribosomal | cypemycin | Streptomyces sp. OH-4156
BGC0001555.4 |  | 0.52 | ribosomal | colicin V | Escherichia coli chi7122
BGC0001201.3 |  | 0.51 | terpene | eremophilene | Sorangium cellulosum So ce56

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for HMPREF2804_RS09425

HMPREF2804_RS11135
Leader:
MDSISLIAEVSDQELAGT
Core:
V G D Q A G G L F T V P G T T T V G H F C T I S W E C S G F I C G K
Core with dehydrations:
V G D Q A G G L F Dhb V P G Dhb Dhb Dhb V G H F Cys Dhb I Dha W E Cys Dha G F I Cys G K

#### antiSMASH-DB 4.0 matches for HMPREF2804_RS11135

100.0%
NC_014643.1 and 2 others:
NZ_KV795763.1 Lanthipeptides: HMPREF2554_RS11600_lanthipeptide NZ_KV804818.1 Lanthipeptides: HMPREF2804_RS11135_lanthipeptide
Lanthipeptides: HMPREF0733_RS11155_lanthipeptide
1
V G D Q A G G L F T V P G T T T V G H F C T I S W E C S G F I C G K
34
V G D Q A G G L F T V P G T T T V G H F C T I S W E C S G F I C G K
1
V G D Q A G G L F T V P G T T T V G H F C T I S W E C S G F I C G K
34
72.2%
NZ_JAPVBQ010000001.1:
Lanthipeptides: O2V63_RS05740_lanthipeptide
1
V G D Q A G G L F T V P G T T T V G H F C T I S W E C S G F I C G
33
V G D Q A G G L F T T T V G C T I S W E C S G I C G
1
V G D Q A G G L F T F K T T K T V G A V C T I S W E C S G R I C G
33
55.9%
NZ_CP051884.1 and 2 others:
NZ_CP051884.1 Lanthipeptides: HGK68_RS15160_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15160_lanthipeptide
Lanthipeptides: HGK68_RS15160_lanthipeptide
4
Q A G G L F T V P G T T T V G H F C T I S W E C S G F I C G K
34
+A G G++T+P G T T+G F C T I S+E C G F+C
1
R A G G I W T I P G T K T I G A F C T I S Y E C W G F V C N N
31
with 52 more sequence matches
Only the first 10 are displayed here.
55.9%
NZ_LR027842.1:
Lanthipeptides: E0E39_RS15855_lanthipeptide
8
L F T V P G T T T V G H F C T I S W E C S G F I C G
33
L+T V P G T T+G C T+S W E C G F I C G
1
L W T V P G T R T I G A V C T V S W E C H G F I C G
26
50.0%
NZ_CP035495.1 and 1 other:
NZ_CP035495.1 Lanthipeptides: ET495_RS17535_lanthipeptide
Lanthipeptides: ET495_RS17535_lanthipeptide
8
L F T V P G T T T V G H F C T I S W E C S G F I C G
33
L+T+P G T+T+G F C T+S W E C G C G
1
L W T I P G T S T I G R F C T L S W E C Q G I A C G
26
44.1%
NZ_PVMZ01000043.1 and 1 other:
NZ_PVMZ01000043.1 Lanthipeptides: CLV67_RS49720_lanthipeptide
Lanthipeptides: CLV67_RS49720_lanthipeptide
8
L F T V P G T T T V G H F C T I S W E C S
28
L F T V P G T+T+G+ C T S+E C S
1
L F T V P G T S T I G Y V C T Y S Y E C S
21
44.1%
NZ_QGGR01000002.1:
Lanthipeptides: BC793_RS05490_lanthipeptide
8
L F T V P G T T T V G H F C T I S W E C S
28
L+T V P G T+T+G C T+S W E C S
1
L Y T V P G T S T I G W I C T V S W E C S
21
38.2%
NZ_CP025227.1:
Lanthipeptides: allorf_0999194_0999376_lanthipeptide
8
L F T V P G T T T V G H F C T I S W E C S
28
L+T V P T+T+G C T+S W E C+
1
L W T V P T T S T I G L V C T L S W E C T
21
29.4%
NC_017912.1 and 14 others:
NZ_CP007242.1 Lanthipeptides: KHU1_RS17410_lanthipeptide NZ_CP031424.1 Lanthipeptides: DXX91_RS18935_lanthipeptide NZ_CP032855.1 Lanthipeptides: D9C11_RS10440_lanthipeptide NZ_CP043809.1 Lanthipeptides: ETZ92_RS14260_lanthipeptide NZ_CP049904.1 Lanthipeptides: V753_RS18470_lanthipeptide NZ_CP053764.1 Lanthipeptides: HPQ66_RS18325_lanthipeptide NZ_CP061938.1 Lanthipeptides: IEN91_RS19800_lanthipeptide NZ_CP063768.1 Lanthipeptides: IM712_RS05205_lanthipeptide NZ_CP087137.1 Lanthipeptides: LOK79_RS18580_lanthipeptide NZ_CP092383.1 Lanthipeptides: MID02_RS19390_lanthipeptide NZ_JAEACM010000001.1 Lanthipeptides: I5F15_RS04355_lanthipeptide NZ_JAJNPN010000015.1 Lanthipeptides: LQ568_RS13285_lanthipeptide NZ_SDKF01000002.1 Lanthipeptides: EUA41_RS09950_lanthipeptide NZ_VDUT01000007.1 Lanthipeptides: FS412_RS14545_lanthipeptide
Lanthipeptides: MUS_RS20065_lanthipeptide
4
Q A G G L F T V P G T T T V G H F C T I S W E C
27
+A F T+P G G C T++ E C
4
E A A C T F T L P G G---G G V C T L T S E C
24
29.4%
NZ_AP024169.1:
Lanthipeptides: bsdtb5_RS06110_lanthipeptide
18
G H F C T I S W E C--S G F I C G K
34
G F T I S+E C + C G K
15
G G F P T I S Y E C T S N N V S C G K
33
27.0%
NZ_CP048273.1 and 1 other:
NZ_CP048273.1 Lanthipeptides: M654_RS18500_lanthipeptide
Lanthipeptides: M654_RS18500_lanthipeptide
18
G H F C T I S W E C S G F I-C G K
34
G +C T S E C+G + C G K
20
G K Y C T W S A E C A G T V S C G K
37
26.5%
NZ_AP024169.1:
Lanthipeptides: bsdtb5_RS06105_lanthipeptide
18
G H F C T I S W E C--S G F I C G K
34
G T I S+E C + C G K
15
G R M P T I S Y E C T S N N V S C G K
33
26.5%
NZ_AUBN01000022.1:
Lanthipeptides: G448_RS16025_lanthipeptide
18
G H F C T I S W E C S G F I C G
33
G F C T++ E C F I C
4
G W F C T L T I E C G T F I C A
19

#### MIBiG 4.0 matches for HMPREF2804_RS11135

14.7%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
18
G H F C T I S W E C
27
G +C T++ E C
14
G A Y C T L T V E C
23
14.7%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
18
G H F C T I S W E C
27
G +C T++ E C
16
G G W C T L T K E C
25
12.8%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
21
C T I S W E C
27
C T+S E C
28
C T L S K E C
34
HMPREF2804_RS09455
Leader:
MAQNDHQDKHPKRKEIPSSLWVFALATFVLALPRIGDGRILPLDLTTSFILGA
Core:
V L I V C G F W M M Y R E H K K S S A Q K K
Core with dehydrations:
V L I V Cys G F W M M Y R E H K K Dha Dha A Q K K

#### antiSMASH-DB 4.0 matches for HMPREF2804_RS09455

100.0%
NZ_JVXR01000038.1 and 6 others:
NZ_KV793075.1 Lanthipeptides: HMPREF3164_RS06965_lanthipeptide NZ_KV797630.1 Lanthipeptides: HMPREF2609_RS05985_lanthipeptide NZ_KV804818.1 Lanthipeptides: HMPREF2804_RS09455_lanthipeptide NZ_KV804818.1 Lanthipeptides: HMPREF2804_RS09455_lanthipeptide NZ_KV804818.1 Lanthipeptides: HMPREF2804_RS09455_lanthipeptide NZ_KV817389.1 Lanthipeptides: HMPREF2981_RS04655_lanthipeptide
Lanthipeptides: ADK06_RS05035_lanthipeptide
1
V L I V C G F W M M Y R E H K K S S A Q K K
22
V L I V C G F W M M Y R E H K K S S A Q K K
1
V L I V C G F W M M Y R E H K K S S A Q K K
22
26.9%
NZ_KZ268499.1:
Lanthipeptides: allorf_4452434_4452649_lanthipeptide
4
V C G F W M M Y R E H K K S S A
19
+C G R H K S S+
6
L C G L C T F I R A H P K S S S
21
20.0%
NZ_CP066762.1:
Lanthipeptides: JG536_RS12630_lanthipeptide
3
I V C G--F W M M Y R E H K K S S
18
I V G M M+R+H K S
5
I V I G A L L A M M H R K H K Y S P
22
with 1 more sequence matches
18.2%
NZ_QPIX01000013.1:
Lanthipeptides: allorf_114776_114868_lanthipeptide
2
L I V C G F W M M Y R E H
14
L+ C W+ Y+++
7
L L A C S H W L R Y K D N
19
allorf_083218_083325
Leader:
MGRGMHEPIAG
Core:
V Q R M R F L T L C E Q A T H D I F Q I Q N I Y
Core with dehydrations:
V Q R M R F L Dhb L Cys E Q A Dhb H D I F Q I Q N I Y

#### antiSMASH-DB 4.0 matches for allorf_083218_083325

24.2%
NZ_CP077072.1:
Lanthipeptides: allorf_2268889_2269032_lanthipeptide
2
Q R M R F L T L C E Q A T H D I F Q I Q N I Y
24
R M R +L A H I Q ++
1
H R M R R R S L V R L A C H R I H Q D G P V H
23
9.8%
NC_002935.2 and 6 others:
NC_016787.1 Lanthipeptides: allorf_0700263_0700493_lanthipeptide NC_016788.1 Lanthipeptides: allorf_0708439_0708669_lanthipeptide NC_016790.1 Lanthipeptides: allorf_0677571_0677801_lanthipeptide NZ_CP038504.1 Lanthipeptides: allorf_0571829_0572059_lanthipeptide NZ_CP040557.1 Lanthipeptides: allorf_0667863_0668093_lanthipeptide NZ_MIOB01000009.1 Lanthipeptides: allorf_00076_00306_lanthipeptide
Lanthipeptides: allorf_0739982_0740212_lanthipeptide
8
T L C E Q A T H D I F Q I Q N I
23
+ C Q + D+F+ Q+I
40
S W C G Q I S P D V F E A Q S I
55
allorf_096778_096948
Leader:
MTILEHIRQA
Core:
T C D T C S Y V E Y I I V S D F Y I Q V N I S S S P K A N F M G Y L T I L L T L C C I P S E
Core with dehydrations:
Dhb Cys D Dhb Cys Dha Y V E Y I I V Dha D F Y I Q V N I Dha Dha Dha P K A N F M G Y L Dhb I L L Dhb L Cys Cys I P Dha E

#### antiSMASH-DB 4.0 matches for allorf_096778_096948

100.0%
NC_014643.1 and 1 other:
NZ_KV804818.1 Lanthipeptides: allorf_096778_096948_lanthipeptide
Lanthipeptides: allorf_1155122_1155292_lanthipeptide
1
T C D T C S Y V E Y I I V S D F Y I Q V N I S S S P K A N F M G Y L T I L L T L C C I P S E
46
T C D T C S Y V E Y I I V S D F Y I Q V N I S S S P K A N F M G Y L T I L L T L C C I P S E
1
T C D T C S Y V E Y I I V S D F Y I Q V N I S S S P K A N F M G Y L T I L L T L C C I P S E
46
26.1%
NZ_JAOQJV010000004.1:
Lanthipeptides: OCV65_RS05205_lanthipeptide
9
E Y I I V S D F Y I Q V N I S S S P K A N F M G Y L T I L L T L C C
42
E Y ++ D Q V + ++ N G+L T I +C C
9
E Y N M L M D E A E Q V V V Y A T Q S G N C S G F L T I---I C C
39
23.9%
NZ_CP013979.1:
Lanthipeptides: allorf_0343557_0343787_lanthipeptide
18
I Q V N I S---S S P K A N F M G Y L T I L L T L C C
42
I V I S S P F G T + C C
10
I G V G I S L A W C S P G G T F C G S C T F G T S G C C
37
with 1 more sequence matches
13.0%
NZ_CP050440.1:
Lanthipeptides: allorf_0199281_0199457_lanthipeptide
14
S D F Y I Q V N I S S S P K A N F M G
32
S+F++Q+ + S P G
2
S E F W V Q I K V D S L P T P K L T G
20

#### MIBiG 4.0 matches for allorf_096778_096948

13.0%
BGC0000563.4 (AEA03263.1):
Lanthipeptide: venezuelin
31
M G Y L T I L L T L C
41
+G L T+L T+C
6
V G L L T L L N T V C
16
allorf_097220_097294
Leader:
MYITTRHHEGGA
Core:
C I Y L L H L K C T V A
Core with dehydrations:
Cys I Y L L H L K Cys Dhb V A

#### antiSMASH-DB 4.0 matches for allorf_097220_097294

100.0%
NC_014643.1 and 1 other:
NZ_KV804818.1 Lanthipeptides: allorf_097220_097294_lanthipeptide
Lanthipeptides: allorf_1154776_1154850_lanthipeptide
1
C I Y L L H L K C T V A
12
C I Y L L H L K C T V A
1
C I Y L L H L K C T V A
12

#### Lanthipeptide(s) for HMPREF2804_RS09470

HMPREF2804_RS09455
Leader:
MAQNDHQDKHPKRKEIPSSLWVFALATFVLALPRIGDGRILPLDLTTSFILGA
Core:
V L I V C G F W M M Y R E H K K S S A Q K K
Core with dehydrations:
V L I V Cys G F W M M Y R E H K K Dha Dha A Q K K

#### antiSMASH-DB 4.0 matches for HMPREF2804_RS09455

100.0%
NZ_JVXR01000038.1 and 6 others:
NZ_KV793075.1 Lanthipeptides: HMPREF3164_RS06965_lanthipeptide NZ_KV797630.1 Lanthipeptides: HMPREF2609_RS05985_lanthipeptide NZ_KV804818.1 Lanthipeptides: HMPREF2804_RS09455_lanthipeptide NZ_KV804818.1 Lanthipeptides: HMPREF2804_RS09455_lanthipeptide NZ_KV804818.1 Lanthipeptides: HMPREF2804_RS09455_lanthipeptide NZ_KV817389.1 Lanthipeptides: HMPREF2981_RS04655_lanthipeptide
Lanthipeptides: ADK06_RS05035_lanthipeptide
1
V L I V C G F W M M Y R E H K K S S A Q K K
22
V L I V C G F W M M Y R E H K K S S A Q K K
1
V L I V C G F W M M Y R E H K K S S A Q K K
22
26.9%
NZ_KZ268499.1:
Lanthipeptides: allorf_4452434_4452649_lanthipeptide
4
V C G F W M M Y R E H K K S S A
19
+C G R H K S S+
6
L C G L C T F I R A H P K S S S
21
20.0%
NZ_CP066762.1:
Lanthipeptides: JG536_RS12630_lanthipeptide
3
I V C G--F W M M Y R E H K K S S
18
I V G M M+R+H K S
5
I V I G A L L A M M H R K H K Y S P
22
with 1 more sequence matches
18.2%
NZ_QPIX01000013.1:
Lanthipeptides: allorf_114776_114868_lanthipeptide
2
L I V C G F W M M Y R E H
14
L+ C W+ Y+++
7
L L A C S H W L R Y K D N
19
HMPREF2804_RS09475
Leader:
MAKDITLLEEISDLDLDQVNGS
Core:
G H G G G G Y S G G G Y N G G G N Y C G N G C G N Y N F G F G F W G G S S S
Core with dehydrations:
G H G G G G Y Dha G G G Y N G G G N Y Cys G N G Cys G N Y N F G F G F W G G Dha Dha Dha

#### antiSMASH-DB 4.0 matches for HMPREF2804_RS09475

100.0%
NZ_KV804818.1 and 1 other:
NZ_KV804818.1 Lanthipeptides: HMPREF2804_RS09475_lanthipeptide
Lanthipeptides: HMPREF2804_RS09475_lanthipeptide
1
G H G G G G Y S G G G Y N G G G N Y C G N G C G N Y N F G F G F W G G S S S
38
G H G G G G Y S G G G Y N G G G N Y C G N G C G N Y N F G F G F W G G S S S
1
G H G G G G Y S G G G Y N G G G N Y C G N G C G N Y N F G F G F W G G S S S
38
86.0%
NZ_KV802313.1:
Lanthipeptides: HMPREF2756_RS06530_lanthipeptide
1
G H G G G G Y S G G G Y N G G G N-----Y C G N G C G N Y N F G F G F W G G S S S
38
G H G G G G Y S G G G Y+G G G N Y C G N G C G N Y N F G F G F W G G S S S
1
G H G G G G Y S G G G Y S G G G N G G G G N Y C G N G C G N Y N F G F G F W G G S S S
43
25.0%
NC_014643.1 and 13 others:
NC_014643.1 Lanthipeptides: HMPREF0733_RS05060_lanthipeptide NZ_CP054018.1 Lanthipeptides: FOC60_RS00340_lanthipeptide NZ_CP079201.1 Lanthipeptides: LPB409_RS01335_lanthipeptide NZ_JVLW01000024.1 Lanthipeptides: ADD47_RS04725_lanthipeptide NZ_JVXR01000038.1 Lanthipeptides: ADK06_RS05015_lanthipeptide NZ_KV793075.1 Lanthipeptides: HMPREF3164_RS06945_lanthipeptide NZ_KV795763.1 Lanthipeptides: HMPREF2554_RS09025_lanthipeptide NZ_KV795763.1 Lanthipeptides: HMPREF2554_RS09025_lanthipeptide NZ_KV797630.1 Lanthipeptides: HMPREF2609_RS06005_lanthipeptide NZ_KV797887.1 Lanthipeptides: HMPREF2625_RS00515_lanthipeptide NZ_KV815277.1 Lanthipeptides: HMPREF2958_RS01940_lanthipeptide NZ_KV817389.1 Lanthipeptides: HMPREF2981_RS04625_lanthipeptide NZ_KV820076.1 Lanthipeptides: HMPREF3016_RS03055_lanthipeptide
Lanthipeptides: HMPREF0733_RS05060_lanthipeptide
28
F G F G F W G G S S S
38
F G F G F W G G S S S
34
F G F G F W G G S S S
44
with 1 more sequence matches
10.0%
NZ_PVTF01000002.1:
Lanthipeptides: allorf_797510_797749_lanthipeptide
23
C G N Y N F G F G F W G G S
36
C G + G F W S
4
C G R L D L G P L F W A S S
17

#### MIBiG 4.0 matches for HMPREF2804_RS09475

10.5%
BGC0002322.3 (CEJ66604.1):
Lasso peptide: citrocin
18
Y C G N G C G N Y
26
+ G G G Y
10
F I G G G V G R Y
18
HMPREF2804_RS11470
Leader:
MPQDITLLEEISEQDLSQVNGG
Core:
T A F P G W Y S K V I G N R G R V C T V T V E C M S V C Q
Core with dehydrations:
Dhb A F P G W Y Dha K V I G N R G R V Cys Dhb V Dhb V E Cys M Dha V Cys Q

#### antiSMASH-DB 4.0 matches for HMPREF2804_RS11470

100.0%
NZ_KV795763.1 and 2 others:
NZ_KV804818.1 Lanthipeptides: allorf_114850_115005_lanthipeptide NZ_KV804818.1 Lanthipeptides: allorf_114850_115005_lanthipeptide
Lanthipeptides: allorf_248182_248337_lanthipeptide
1
T A F P G W Y S K V I G N R G R V C T V T V E C M S V C Q
29
T A F P G W Y S K V I G N R G R V C T V T V E C M S V C Q
1
T A F P G W Y S K V I G N R G R V C T V T V E C M S V C Q
29
50.0%
NZ_CP043405.1 and 1 other:
NZ_CP043405.1 Lanthipeptides: FY406_RS04355_lanthipeptide
Lanthipeptides: FY406_RS04355_lanthipeptide
1
T A F P G W Y S K V I G N R G R V C T V T V E C M S V C Q
29
T +S V+G N+G +C T V T V E C M C Q
4
T V V N S T F S I V L G N K G Y I C T V T V E C M R N C Q
32
48.3%
NZ_CP006058.1 and 23 others:
NZ_CP006058.1 Lanthipeptides: BAMY6639_RS13800_lanthipeptide NZ_CP021892.1 Lanthipeptides: S100333_RS03315_lanthipeptide NZ_CP021892.1 Lanthipeptides: S100333_RS03315_lanthipeptide NZ_CP026533.1 Lanthipeptides: C3438_RS12905_lanthipeptide NZ_CP026533.1 Lanthipeptides: C3438_RS12905_lanthipeptide NZ_CP028961.1 Lanthipeptides: DBK22_RS18395_lanthipeptide NZ_CP028961.1 Lanthipeptides: DBK22_RS18395_lanthipeptide NZ_CP032855.1 Lanthipeptides: D9C11_RS14690_lanthipeptide NZ_CP032855.1 Lanthipeptides: D9C11_RS14690_lanthipeptide NZ_CP044132.1 Lanthipeptides: F5K02_RS03560_lanthipeptide NZ_CP044132.1 Lanthipeptides: F5K02_RS03560_lanthipeptide NZ_CP061087.1 Lanthipeptides: IAR44_RS03165_lanthipeptide NZ_CP061087.1 Lanthipeptides: IAR44_RS03165_lanthipeptide NZ_CP065791.1 Lanthipeptides: I8N73_RS03395_lanthipeptide NZ_CP065791.1 Lanthipeptides: I8N73_RS03395_lanthipeptide NZ_CP074348.1 Lanthipeptides: KHA74_RS03200_lanthipeptide NZ_CP074348.1 Lanthipeptides: KHA74_RS03200_lanthipeptide NZ_CP083943.1 Lanthipeptides: LCH16_RS03220_lanthipeptide NZ_CP083943.1 Lanthipeptides: LCH16_RS03220_lanthipeptide NZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10965_lanthipeptide NZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10965_lanthipeptide NZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15475_lanthipeptide NZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15475_lanthipeptide
Lanthipeptides: BAMY6639_RS13800_lanthipeptide
5
G W Y--S K V I G N R G R V C T V T V E C M S V C Q
29
W Y S +G N+G C T+T V E C S C
2
A W Y D I S C K L G N K G A W C T L T V E C Q S S C N
28
with 108 more sequence matches
Only the first 10 are displayed here.
48.3%
NZ_CP025249.1 and 1 other:
NZ_CP025249.1 Lanthipeptides: CWT12_RS00385_lanthipeptide
Lanthipeptides: CWT12_RS00385_lanthipeptide
3
F P G W Y S K V I G N R G R V C T V T V E C M S V C Q
29
F P W S+ +G N G V C T+T E C +C
2
F P-W L S R K L G N T G Y V C T L T K E C Q R M C N
27
48.3%
NZ_FOBE01000018.1:
Lanthipeptides: BMW61_RS13085_lanthipeptide
5
G W Y S K V---I G N R G R V C T V T V E C M S V C Q
29
G W Y S++ +G N R G C T+T E C + C
1
G W Y S E M S A A L G N R G S Y C T L T K E C Q A C C N
28
48.3%
NZ_LR134483.1 and 1 other:
NZ_LR134483.1 Lanthipeptides: EL241_RS01725_lanthipeptide
Lanthipeptides: EL241_RS01725_lanthipeptide
5
G W--Y S K V I G N R G R V C T V T V E C M S V C Q
29
G W S K +G N+G V C T+T E C +C+
2
G W K D L S K S L G N K G Y V C T L T K E C Q K L C R
28
45.5%
NC_018089.1 and 11 others:
NC_018089.1 Lanthipeptides: SMUGS5_RS08725_lanthipeptide NZ_CP044493.1 Lanthipeptides: FSA40_RS09065_lanthipeptide NZ_CP044493.1 Lanthipeptides: FSA40_RS09065_lanthipeptide NZ_CP050270.1 Lanthipeptides: HB753_RS00325_lanthipeptide NZ_CP050270.1 Lanthipeptides: HB753_RS00325_lanthipeptide NZ_JADPAN010000004.1 Lanthipeptides: I4U28_RS03985_lanthipeptide NZ_JADPAN010000004.1 Lanthipeptides: I4U28_RS03985_lanthipeptide NZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS08120_lanthipeptide NZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS08120_lanthipeptide NZ_JAQCYD010000003.1 Lanthipeptides: PGX70_RS05515_lanthipeptide NZ_JAQCYD010000003.1 Lanthipeptides: PGX70_RS05515_lanthipeptide
Lanthipeptides: SMUGS5_RS08725_lanthipeptide
1
T A F P G W Y S K V I G N R G R V C T V T V E C M S V C Q
29
T +S V+G N+G +C T V T V E C M C
4
T V V N S T F S I V L G N K G Y I C T V T V E C M R N C S
32
44.8%
NZ_CP030280.1 and 1 other:
NZ_CP030280.1 Lanthipeptides: DQQ01_RS07655_lanthipeptide
Lanthipeptides: DQQ01_RS07655_lanthipeptide
8
S K V I G N R G R V C T V T V E C M S V C Q
29
S K G N G +C+V T V E C M +C
3
S K D W G N D G Y L C S V T V E C M I I C N
24
44.8%
NZ_CP030280.1 and 3 others:
NZ_CP030280.1 Lanthipeptides: DQQ01_RS07645_lanthipeptide NZ_CP030280.1 Lanthipeptides: DQQ01_RS07650_lanthipeptide NZ_CP030280.1 Lanthipeptides: DQQ01_RS07645_lanthipeptide
Lanthipeptides: DQQ01_RS07650_lanthipeptide
8
S K V I G N R G R V C T V T V E C M S V C Q
29
S K G N G +C+V T V E C M +C
3
S K D W G N D G Y L C S V T V E C M V I C N
24
44.8%
NZ_CP063276.1 and 1 other:
NZ_CP063276.1 Lanthipeptides: IM743_RS02795_lanthipeptide
Lanthipeptides: IM743_RS02795_lanthipeptide
5
G W Y--S K V I G N R G R V C T V T V E C M S V C Q
29
W Y S +G N+G C T+T V E C + C
2
A W Y D V S C R L G N K G A W C T L T V E C Q N N C N
28
44.8%
NZ_KE384107.1:
Lanthipeptides: G586_RS23925_lanthipeptide
5
G W Y S K V---I G N R G R V C T V T V E C M S V C Q
29
G W Y+ + +G N R G C T+T E C + C
1
G W Y A D L S A S L G N R G S Y C T I T K E C Q A C C N
28
44.8%
NZ_LR134483.1 and 1 other:
NZ_LR134483.1 Lanthipeptides: EL241_RS01720_lanthipeptide
Lanthipeptides: EL241_RS01720_lanthipeptide
8
S K V I G N R G R V C T V T V E C M S V C Q
29
S K +G N+G R+C T+T E C S+C
5
S K N L G N K G R I C T L T K E C Q S M C N
26
43.8%
NC_002570.2 and 3 others:
NC_002570.2 Lanthipeptides: AYT26_RS02480_lanthipeptide NZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptide NZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptide
Lanthipeptides: AYT26_RS02480_lanthipeptide
5
G W Y--S K V I G N R G R V C T V T V E C M S V C Q
29
W Y S +G N+G C T+T V E C M C
6
A W Y N I S C R L G N K G A Y C T L T V E C M P S C N
32

#### MIBiG 4.0 matches for HMPREF2804_RS11470

48.3%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
5
G W Y--S K V I G N R G R V C T V T V E C M S V C Q
29
W Y S +G N+G C T+T V E C M C
2
A W Y N I S C R L G N K G A Y C T L T V E C M P S C N
28
33.3%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
8
S K V I G N R G R V C T V T V E C M S V C Q
29
S +G N G C T+T E C C
9
S N A L G N N G G W C T L T K E C Q P N C N
30
12.8%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
18
C T V T V E C M S V C Q
29
C T++ E C C
28
C T L S K E C Q P N C N
39
allorf_096778_096948
Leader:
MTILEHIRQA
Core:
T C D T C S Y V E Y I I V S D F Y I Q V N I S S S P K A N F M G Y L T I L L T L C C I P S E
Core with dehydrations:
Dhb Cys D Dhb Cys Dha Y V E Y I I V Dha D F Y I Q V N I Dha Dha Dha P K A N F M G Y L Dhb I L L Dhb L Cys Cys I P Dha E

#### antiSMASH-DB 4.0 matches for allorf_096778_096948

100.0%
NC_014643.1 and 1 other:
NZ_KV804818.1 Lanthipeptides: allorf_096778_096948_lanthipeptide
Lanthipeptides: allorf_1155122_1155292_lanthipeptide
1
T C D T C S Y V E Y I I V S D F Y I Q V N I S S S P K A N F M G Y L T I L L T L C C I P S E
46
T C D T C S Y V E Y I I V S D F Y I Q V N I S S S P K A N F M G Y L T I L L T L C C I P S E
1
T C D T C S Y V E Y I I V S D F Y I Q V N I S S S P K A N F M G Y L T I L L T L C C I P S E
46
26.1%
NZ_JAOQJV010000004.1:
Lanthipeptides: OCV65_RS05205_lanthipeptide
9
E Y I I V S D F Y I Q V N I S S S P K A N F M G Y L T I L L T L C C
42
E Y ++ D Q V + ++ N G+L T I +C C
9
E Y N M L M D E A E Q V V V Y A T Q S G N C S G F L T I---I C C
39
23.9%
NZ_CP013979.1:
Lanthipeptides: allorf_0343557_0343787_lanthipeptide
18
I Q V N I S---S S P K A N F M G Y L T I L L T L C C
42
I V I S S P F G T + C C
10
I G V G I S L A W C S P G G T F C G S C T F G T S G C C
37
with 1 more sequence matches
13.0%
NZ_CP050440.1:
Lanthipeptides: allorf_0199281_0199457_lanthipeptide
14
S D F Y I Q V N I S S S P K A N F M G
32
S+F++Q+ + S P G
2
S E F W V Q I K V D S L P T P K L T G
20

#### MIBiG 4.0 matches for allorf_096778_096948

13.0%
BGC0000563.4 (AEA03263.1):
Lanthipeptide: venezuelin
31
M G Y L T I L L T L C
41
+G L T+L T+C
6
V G L L T L L N T V C
16
allorf_097220_097294
Leader:
MYITTRHHEGGA
Core:
C I Y L L H L K C T V A
Core with dehydrations:
Cys I Y L L H L K Cys Dhb V A

#### antiSMASH-DB 4.0 matches for allorf_097220_097294

100.0%
NC_014643.1 and 1 other:
NZ_KV804818.1 Lanthipeptides: allorf_097220_097294_lanthipeptide
Lanthipeptides: allorf_1154776_1154850_lanthipeptide
1
C I Y L L H L K C T V A
12
C I Y L L H L K C T V A
1
C I Y L L H L K C T V A
12
allorf_109292_109366
Leader:
MLLRNLNFM
Core:
G E I L C G L R G T C R A G F
Core with dehydrations:
G E I L Cys G L R G Dhb Cys R A G F

#### antiSMASH-DB 4.0 matches for allorf_109292_109366

100.0%
NZ_CP054018.1 and 3 others:
NZ_KV804818.1 Lanthipeptides: allorf_109292_109366_lanthipeptide NZ_KV804818.1 Lanthipeptides: allorf_109292_109366_lanthipeptide NZ_KV820076.1 Lanthipeptides: allorf_134599_134673_lanthipeptide
Lanthipeptides: allorf_0084035_0084109_lanthipeptide
1
G E I L C G L R G T C R A G F
15
G E I L C G L R G T C R A G F
1
G E I L C G L R G T C R A G F
15
25.0%
NZ_KB900614.1:
Lanthipeptides: allorf_2952909_2953064_lanthipeptide
4
L C G L R G T C R A G F
15
+C +G C R G F
7
V C A F K G H C R I G F
18
allorf_109330_109521
Leader:
MRFEGNLPRWFLKKHQKNLDAVAQA
Core:
A R L C D S I H V F R L L Y G S G Y L L V Q A A T H I H N D F P K P Q G R L
Core with dehydrations:
A R L Cys D Dha I H V F R L L Y G Dha G Y L L V Q A A Dhb H I H N D F P K P Q G R L

#### antiSMASH-DB 4.0 matches for allorf_109330_109521

100.0%
NZ_KV804818.1 and 1 other:
NZ_KV804818.1 Lanthipeptides: allorf_109330_109521_lanthipeptide
Lanthipeptides: allorf_109330_109521_lanthipeptide
1
A R L C D S I H V F R L L Y G S G Y L L V Q A A T H I H N D F P K P Q G R L
38
A R L C D S I H V F R L L Y G S G Y L L V Q A A T H I H N D F P K P Q G R L
1
A R L C D S I H V F R L L Y G S G Y L L V Q A A T H I H N D F P K P Q G R L
38
18.4%
NZ_NIST01000001.1:
Lassopeptides: CD001_RS25955_lassopeptide
25
T H I H N D F P K P Q G R
37
+H+ N D F P+ G R
1
S H L D N D F P E G T G R
13
15.8%
NZ_JVXR01000038.1:
Lanthipeptides: allorf_10259_10360_lanthipeptide
1
A R L C D S I H
8
A R L C D S+
1
A R L C D S V Q
8
allorf_115697_115819
Leader:
MRVLIYLSVIEAKTSLAR
Core:
W R I P G D I S P E I C G T P R R V L T S T
Core with dehydrations:
W R I P G D I Dha P E I Cys G Dhb P R R V L Dhb Dha Dhb

#### antiSMASH-DB 4.0 matches for allorf_115697_115819

100.0%
NZ_KV804818.1 and 1 other:
NZ_KV804818.1 Lanthipeptides: allorf_115697_115819_lanthipeptide
Lanthipeptides: allorf_115697_115819_lanthipeptide
1
W R I P G D I S P E I C G T P R R V L T S T
22
W R I P G D I S P E I C G T P R R V L T S T
1
W R I P G D I S P E I C G T P R R V L T S T
22
30.0%
NC_018499.1 and 1 other:
NC_018499.1 Lanthipeptides: BCK_RS27825_lanthipeptide
Lanthipeptides: BCK_RS27825_lanthipeptide
5
G D I S P E I C G T P R R V L T
20
G D++P E I T P V T
1
G D V N P E I A P T P H T V T T
16
29.2%
NZ_FUXI01000002.1:
Lanthipeptides: B5D30_RS01240_lanthipeptide
5
G D I S P E I C G T P R R V L T S
21
G D++P+ G+ L T S
1
G D V N P Q T V G S L W E F L T S
17
with 9 more sequence matches
26.7%
NZ_MLKL01000042.1:
Lanthipeptides: BKK45_RS27420_lanthipeptide
5
G D I S P E I C G T P R R V L T
20
G D++P E T P V T
1
G D V N P E T A P T P H T V T T
16
25.0%
NZ_JACIJS010000004.1:
Lanthipeptides: allorf_030388_030501_lanthipeptide
5
G D I S P E I C G T
14
G D+S P +C G
2
G D L S P C V C G A
11
25.0%
NZ_QSIO01000003.1:
Lanthipeptides: DW820_RS07295_lanthipeptide
5
G D I S P E I C G T P R R V L
19
G D I S P E T P V L
1
G D I S P E T--T P A C V L
13
20.0%
NZ_CP075910.1 and 3 others:
NZ_CP075971.1 Lanthipeptides: KLF29_RS14850_lanthipeptide NZ_CP075982.1 Lanthipeptides: KLF51_RS14900_lanthipeptide NZ_CP075994.1 Lanthipeptides: KLF26_RS16110_lanthipeptide
Lanthipeptides: KLF45_RS14835_lanthipeptide
1
W R I P G D I S P E I C G T P R R V L T
20
+ P G ++ E+C G+ L T
6
Y C T P G C L T G E L C G S S E C G L T
25
17.6%
NZ_CABIWO010000014.1:
Lanthipeptides: FY209_RS17155_lanthipeptide
1
W R I P G D I S P E I C G T P R R V L T
20
+ P G ++ ++C G+ L T
5
Y C T P G C V T G Q L C G S S E C G L T
24
17.1%
NC_018499.1 and 1 other:
NC_018499.1 Lanthipeptides: BCK_RS27830_lanthipeptide
Lanthipeptides: BCK_RS27830_lanthipeptide
5
G D I S P E I C G T P
15
G D++P E I P
1
G D V N P E I M S D P
11
15.0%
NZ_JAFHCX010000012.1 and 1 other:
NZ_LR738722.1 Lanthipeptides: STREPSUIS_RS04075_lanthipeptide
Lanthipeptides: JXW96_RS06965_lanthipeptide
5
G D I S P E
10
G D I S P E
1
G D I S P E
6
14.6%
NZ_CP051486.1:
Lanthipeptides: allorf_6974648_6974821_lanthipeptide
2
R I P G D I S P E I C G T
14
R+P G + P C G
10
R V P G R V L P G R C G A
22
10.7%
NC_016582.1:
Lanthipeptides: allorf_10870098_10870307_lanthipeptide
12
C G T P R R V L
19
C G T R R+L
16
C G T S R R L L
23
allorf_115961_116155
Leader:
MVTSATIQVKVCTVGYGFRIHLYRQVKSLYS
Core:
P C L G Q G R V S S P S N L H I I L R P L S M F G V V I R K Y F D
Core with dehydrations:
P Cys L G Q G R V Dha Dha P Dha N L H I I L R P L Dha M F G V V I R K Y F D

#### antiSMASH-DB 4.0 matches for allorf_115961_116155

100.0%
NZ_KV795763.1 and 2 others:
NZ_KV804818.1 Lanthipeptides: allorf_115961_116155_lanthipeptide NZ_KV804818.1 Lanthipeptides: allorf_115961_116155_lanthipeptide
Lanthipeptides: allorf_249293_249487_lanthipeptide
1
P C L G Q G R V S S P S N L H I I L R P L S M F G V V I R K Y F D
33
P C L G Q G R V S S P S N L H I I L R P L S M F G V V I R K Y F D
1
P C L G Q G R V S S P S N L H I I L R P L S M F G V V I R K Y F D
33
24.2%
NZ_BMUN01000001.1 and 9 others:
NZ_CP012382.1 Lanthipeptides: SAM23877_RS36835_lanthipeptide NZ_CP012949.1 Lanthipeptides: SAM40697_RS33360_lanthipeptide NZ_CP027299.1 Lanthipeptides: C1N79_RS34825_lanthipeptide NZ_CP039123.1 Lanthipeptides: E5N77_RS35110_lanthipeptide NZ_CP104697.1 Lanthipeptides: N6Q81_RS33410_lanthipeptide NZ_CP104697.1 Lanthipeptides: N6Q81_RS33410_lanthipeptide NZ_JACWAA010000001.1 Lanthipeptides: ICA23_RS00945_lanthipeptide NZ_KZ195574.1 Lanthipeptides: B9W62_RS39030_lanthipeptide NZ_MQUH01000030.1 Lanthipeptides: BSZ07_RS37165_lanthipeptide
Lanthipeptides: IE238_RS00870_lanthipeptide
3
L G Q G R V S S P S N L H I I L R
19
G Q G +S P S+ I R
3
F G Q G T F T S P S S Y A I G T R
19
24.2%
NZ_CP043959.1 and 8 others:
NZ_CP054939.1 Lanthipeptides: HUT14_RS33610_lanthipeptide NZ_CP104864.1 Lanthipeptides: N7E53_RS01070_lanthipeptide NZ_FKJH01000076.1 Lanthipeptides: STEPF7_RS31605_lanthipeptide NZ_GG657758.1 Lanthipeptides: SSRG_RS36710_lanthipeptide NZ_JMLN01000003.1 Lanthipeptides: BR33_RS35695_lanthipeptide NZ_KL503830.1 Lanthipeptides: DJ64_RS34550_lanthipeptide NZ_VIUV01000001.1 Lanthipeptides: FB570_RS00565_lanthipeptide NZ_WUUF01000042.1 Lanthipeptides: GSE51_RS09870_lanthipeptide
Lanthipeptides: F3L20_RS18420_lanthipeptide
3
L G Q G R V S S P S N L H I I L R
19
G Q G +S P S+ I R
3
F G Q G T Y T S P S S Y A I G T R
19
with 5 more sequence matches
24.2%
NZ_CP058273.1:
Lanthipeptides: AY578_RS00390_lanthipeptide
4
G Q G R V S S P S N L H I I L R
19
G Q G +S P S+ I R
1
G Q G T Y T S P S S Y A I G T R
16
21.2%
NZ_BEWD01000004.1 and 5 others:
NZ_BMVQ01000001.1 Lanthipeptides: IE283_RS00890_lanthipeptide NZ_BMWI01000001.1 Lanthipeptides: IE253_RS05465_lanthipeptide NZ_CP042324.1 Lanthipeptides: FQ762_RS01285_lanthipeptide NZ_GG657756.1 Lanthipeptides: SSPG_RS36720_lanthipeptide NZ_LT629768.1 Lanthipeptides: BLU60_RS01655_lanthipeptide
Lanthipeptides: Sru02f_RS16280_lanthipeptide
3
L G Q G R V S S P S N L H I I L R
19
G+G +S P S+ I R
3
F G E G T F T S P S S Y A I G T R
19
21.2%
NZ_CP023699.1:
Lassopeptides: CP970_RS43860_lassopeptide
19
R P L S M F G V V I R
29
R P L F G+ I R
5
R P L D S F G L N I R
15
20.0%
NZ_CP067396.1:
Lanthipeptides: JHW41_RS12400_lanthipeptide
9
S S P S N L H I I L R P L S M
23
+ P S H +L R L S M
8
T G P S G A H G L L R C L S M
22
13.3%
NZ_CP078093.1:
Lanthipeptides: KVH43_RS13030_lanthipeptide
15
H I I L R P L S M F G V V I R K Y
31
+ + P L+ + V+ R K Y
1
N W T M N P L T C Y T V L S R K Y
17
allorf_117600_117668
Leader:
MSPYFQDLSLIHAA
Core:
L Q T C L T K S
Core with dehydrations:
L Q Dhb Cys L Dhb K Dha

#### antiSMASH-DB 4.0 matches for allorf_117600_117668

100.0%
NZ_KV795763.1 and 2 others:
NZ_KV804818.1 Lanthipeptides: allorf_117600_117668_lanthipeptide NZ_KV804818.1 Lanthipeptides: allorf_117600_117668_lanthipeptide
Lanthipeptides: allorf_250932_251000_lanthipeptide
1
L Q T C L T K S
8
L Q T C L T K S
1
L Q T C L T K S
8
allorf_117642_117731
Leader:
MFTLSGLNAWSGS
Core:
F L L I Y S F H L A F C K T C L
Core with dehydrations:
F L L I Y Dha F H L A F Cys K Dhb Cys L

#### antiSMASH-DB 4.0 matches for allorf_117642_117731

100.0%
NZ_KV795763.1 and 2 others:
NZ_KV804818.1 Lanthipeptides: allorf_117642_117731_lanthipeptide NZ_KV804818.1 Lanthipeptides: allorf_117642_117731_lanthipeptide
Lanthipeptides: allorf_250974_251063_lanthipeptide
1
F L L I Y S F H L A F C K T C L
16
F L L I Y S F H L A F C K T C L
1
F L L I Y S F H L A F C K T C L
16
23.1%
NC_014483.2 and 18 others:
NC_014622.2 Lanthipeptides: PPSC2_RS36205_lanthipeptide NC_017542.1 Lanthipeptides: PPM_RS07465_lanthipeptide NZ_CP006872.1 Lanthipeptides: PPSQR21_RS07740_lanthipeptide NZ_CP023711.1 Lanthipeptides: CPY53_RS22235_lanthipeptide NZ_CP025957.1 Lanthipeptides: C1A50_RS07530_lanthipeptide NZ_CP029370.1 Lanthipeptides: DI243_RS07495_lanthipeptide NZ_CP040829.1 Lanthipeptides: FGY93_RS00500_lanthipeptide NZ_CP049598.1 Lanthipeptides: G7L40_RS00115_lanthipeptide NZ_CP073682.1 Lanthipeptides: KAI36_RS07745_lanthipeptide NZ_CP084033.1 Lanthipeptides: LAZ93_RS07550_lanthipeptide NZ_CP085682.1 Lanthipeptides: LJR53_RS07370_lanthipeptide NZ_CP086373.1 Lanthipeptides: LMH85_RS07780_lanthipeptide NZ_CP092779.1 Lanthipeptides: MJ749_RS07440_lanthipeptide NZ_CP097766.1 Lanthipeptides: MF620_RS07485_lanthipeptide NZ_CP102865.1 Lanthipeptides: NWS42_RS21195_lanthipeptide NZ_JAKVDC010000001.1 Lanthipeptides: MKN04_RS02755_lanthipeptide NZ_JWJJ01000002.1 Lanthipeptides: U707_RS10390_lanthipeptide NZ_POVT01000009.1 Lanthipeptides: C1T20_RS05900_lanthipeptide
Lanthipeptides: PPE_RS07020_lanthipeptide
7
F H L A F C K T C
15
L+F C K T C
18
V S L S F C K T C
26
23.1%
NC_023037.2 and 11 others:
NZ_CP017967.2 Lanthipeptides: PPYC1_RS07755_lanthipeptide NZ_CP017968.3 Lanthipeptides: PPYC2_RS08330_lanthipeptide NZ_CP061172.1 Lanthipeptides: IAQ67_RS07480_lanthipeptide NZ_CP073683.1 Lanthipeptides: KAI37_RS07495_lanthipeptide NZ_CP109848.1 Lanthipeptides: OF859_RS22650_lanthipeptide NZ_CP113973.1 Lanthipeptides: OYT09_RS07785_lanthipeptide NZ_FOYG01000001.1 Lanthipeptides: BM358_RS03525_lanthipeptide NZ_JAAMNR010000001.1 Lanthipeptides: G9G54_RS03500_lanthipeptide NZ_PNXQ01000013.1 Lanthipeptides: C1I60_RS14430_lanthipeptide NZ_POVS01000009.1 Lanthipeptides: C1T21_RS10630_lanthipeptide NZ_PTJM01000020.1 Lanthipeptides: C5G87_RS02825_lanthipeptide
Lanthipeptides: X809_RS07820_lanthipeptide
7
F H L A F C K T C
15
L F C K T C
18
V S L T F C K T C
26
with 3 more sequence matches
19.2%
NZ_JAIFIS010000001.1:
Lanthipeptides: K1X09_RS26315_lanthipeptide
7
F H L A F C K T C
15
L+F C+T C
18
I S L S F C R T C
26
18.6%
NZ_QKUF01000009.1:
Lanthipeptides: allorf_200737_200904_lanthipeptide
2
L L I Y S F H L A F C K T C
15
L L I S F F C+ C
24
L L I R S F S Y N F C R Q C
37
11.8%
NZ_BOSN01000007.1 and 3 others:
NZ_BOSN01000007.1 Lanthipeptides: allorf_257698_257880_lanthipeptide NZ_JAHHXV010000040.1 Lanthipeptides: allorf_13614_13796_lanthipeptide NZ_JAHHXV010000040.1 Lanthipeptides: allorf_13614_13796_lanthipeptide
Lanthipeptides: allorf_257698_257880_lanthipeptide
4
I Y S F H L A F C K T C
15
+Y S F++ C T C
16
L Y S F Y I H K C S T C
27

#### Lanthipeptide(s) for HMPREF2804_RS09490

HMPREF2804_RS09455
Leader:
MAQNDHQDKHPKRKEIPSSLWVFALATFVLALPRIGDGRILPLDLTTSFILGA
Core:
V L I V C G F W M M Y R E H K K S S A Q K K
Core with dehydrations:
V L I V Cys G F W M M Y R E H K K Dha Dha A Q K K

#### antiSMASH-DB 4.0 matches for HMPREF2804_RS09455

100.0%
NZ_JVXR01000038.1 and 6 others:
NZ_KV793075.1 Lanthipeptides: HMPREF3164_RS06965_lanthipeptide NZ_KV797630.1 Lanthipeptides: HMPREF2609_RS05985_lanthipeptide NZ_KV804818.1 Lanthipeptides: HMPREF2804_RS09455_lanthipeptide NZ_KV804818.1 Lanthipeptides: HMPREF2804_RS09455_lanthipeptide NZ_KV804818.1 Lanthipeptides: HMPREF2804_RS09455_lanthipeptide NZ_KV817389.1 Lanthipeptides: HMPREF2981_RS04655_lanthipeptide
Lanthipeptides: ADK06_RS05035_lanthipeptide
1
V L I V C G F W M M Y R E H K K S S A Q K K
22
V L I V C G F W M M Y R E H K K S S A Q K K
1
V L I V C G F W M M Y R E H K K S S A Q K K
22
26.9%
NZ_KZ268499.1:
Lanthipeptides: allorf_4452434_4452649_lanthipeptide
4
V C G F W M M Y R E H K K S S A
19
+C G R H K S S+
6
L C G L C T F I R A H P K S S S
21
20.0%
NZ_CP066762.1:
Lanthipeptides: JG536_RS12630_lanthipeptide
3
I V C G--F W M M Y R E H K K S S
18
I V G M M+R+H K S
5
I V I G A L L A M M H R K H K Y S P
22
with 1 more sequence matches
18.2%
NZ_QPIX01000013.1:
Lanthipeptides: allorf_114776_114868_lanthipeptide
2
L I V C G F W M M Y R E H
14
L+ C W+ Y+++
7
L L A C S H W L R Y K D N
19
HMPREF2804_RS09475
Leader:
MAKDITLLEEISDLDLDQVNGS
Core:
G H G G G G Y S G G G Y N G G G N Y C G N G C G N Y N F G F G F W G G S S S
Core with dehydrations:
G H G G G G Y Dha G G G Y N G G G N Y Cys G N G Cys G N Y N F G F G F W G G Dha Dha Dha

#### antiSMASH-DB 4.0 matches for HMPREF2804_RS09475

100.0%
NZ_KV804818.1 and 1 other:
NZ_KV804818.1 Lanthipeptides: HMPREF2804_RS09475_lanthipeptide
Lanthipeptides: HMPREF2804_RS09475_lanthipeptide
1
G H G G G G Y S G G G Y N G G G N Y C G N G C G N Y N F G F G F W G G S S S
38
G H G G G G Y S G G G Y N G G G N Y C G N G C G N Y N F G F G F W G G S S S
1
G H G G G G Y S G G G Y N G G G N Y C G N G C G N Y N F G F G F W G G S S S
38
86.0%
NZ_KV802313.1:
Lanthipeptides: HMPREF2756_RS06530_lanthipeptide
1
G H G G G G Y S G G G Y N G G G N-----Y C G N G C G N Y N F G F G F W G G S S S
38
G H G G G G Y S G G G Y+G G G N Y C G N G C G N Y N F G F G F W G G S S S
1
G H G G G G Y S G G G Y S G G G N G G G G N Y C G N G C G N Y N F G F G F W G G S S S
43
25.0%
NC_014643.1 and 13 others:
NC_014643.1 Lanthipeptides: HMPREF0733_RS05060_lanthipeptide NZ_CP054018.1 Lanthipeptides: FOC60_RS00340_lanthipeptide NZ_CP079201.1 Lanthipeptides: LPB409_RS01335_lanthipeptide NZ_JVLW01000024.1 Lanthipeptides: ADD47_RS04725_lanthipeptide NZ_JVXR01000038.1 Lanthipeptides: ADK06_RS05015_lanthipeptide NZ_KV793075.1 Lanthipeptides: HMPREF3164_RS06945_lanthipeptide NZ_KV795763.1 Lanthipeptides: HMPREF2554_RS09025_lanthipeptide NZ_KV795763.1 Lanthipeptides: HMPREF2554_RS09025_lanthipeptide NZ_KV797630.1 Lanthipeptides: HMPREF2609_RS06005_lanthipeptide NZ_KV797887.1 Lanthipeptides: HMPREF2625_RS00515_lanthipeptide NZ_KV815277.1 Lanthipeptides: HMPREF2958_RS01940_lanthipeptide NZ_KV817389.1 Lanthipeptides: HMPREF2981_RS04625_lanthipeptide NZ_KV820076.1 Lanthipeptides: HMPREF3016_RS03055_lanthipeptide
Lanthipeptides: HMPREF0733_RS05060_lanthipeptide
28
F G F G F W G G S S S
38
F G F G F W G G S S S
34
F G F G F W G G S S S
44
with 1 more sequence matches
10.0%
NZ_PVTF01000002.1:
Lanthipeptides: allorf_797510_797749_lanthipeptide
23
C G N Y N F G F G F W G G S
36
C G + G F W S
4
C G R L D L G P L F W A S S
17

#### MIBiG 4.0 matches for HMPREF2804_RS09475

10.5%
BGC0002322.3 (CEJ66604.1):
Lasso peptide: citrocin
18
Y C G N G C G N Y
26
+ G G G Y
10
F I G G G V G R Y
18
HMPREF2804_RS11470
Leader:
MPQDITLLEEISEQDLSQVNGG
Core:
T A F P G W Y S K V I G N R G R V C T V T V E C M S V C Q
Core with dehydrations:
Dhb A F P G W Y Dha K V I G N R G R V Cys Dhb V Dhb V E Cys M Dha V Cys Q

#### antiSMASH-DB 4.0 matches for HMPREF2804_RS11470

100.0%
NZ_KV795763.1 and 2 others:
NZ_KV804818.1 Lanthipeptides: allorf_114850_115005_lanthipeptide NZ_KV804818.1 Lanthipeptides: allorf_114850_115005_lanthipeptide
Lanthipeptides: allorf_248182_248337_lanthipeptide
1
T A F P G W Y S K V I G N R G R V C T V T V E C M S V C Q
29
T A F P G W Y S K V I G N R G R V C T V T V E C M S V C Q
1
T A F P G W Y S K V I G N R G R V C T V T V E C M S V C Q
29
50.0%
NZ_CP043405.1 and 1 other:
NZ_CP043405.1 Lanthipeptides: FY406_RS04355_lanthipeptide
Lanthipeptides: FY406_RS04355_lanthipeptide
1
T A F P G W Y S K V I G N R G R V C T V T V E C M S V C Q
29
T +S V+G N+G +C T V T V E C M C Q
4
T V V N S T F S I V L G N K G Y I C T V T V E C M R N C Q
32
48.3%
NZ_CP006058.1 and 23 others:
NZ_CP006058.1 Lanthipeptides: BAMY6639_RS13800_lanthipeptide NZ_CP021892.1 Lanthipeptides: S100333_RS03315_lanthipeptide NZ_CP021892.1 Lanthipeptides: S100333_RS03315_lanthipeptide NZ_CP026533.1 Lanthipeptides: C3438_RS12905_lanthipeptide NZ_CP026533.1 Lanthipeptides: C3438_RS12905_lanthipeptide NZ_CP028961.1 Lanthipeptides: DBK22_RS18395_lanthipeptide NZ_CP028961.1 Lanthipeptides: DBK22_RS18395_lanthipeptide NZ_CP032855.1 Lanthipeptides: D9C11_RS14690_lanthipeptide NZ_CP032855.1 Lanthipeptides: D9C11_RS14690_lanthipeptide NZ_CP044132.1 Lanthipeptides: F5K02_RS03560_lanthipeptide NZ_CP044132.1 Lanthipeptides: F5K02_RS03560_lanthipeptide NZ_CP061087.1 Lanthipeptides: IAR44_RS03165_lanthipeptide NZ_CP061087.1 Lanthipeptides: IAR44_RS03165_lanthipeptide NZ_CP065791.1 Lanthipeptides: I8N73_RS03395_lanthipeptide NZ_CP065791.1 Lanthipeptides: I8N73_RS03395_lanthipeptide NZ_CP074348.1 Lanthipeptides: KHA74_RS03200_lanthipeptide NZ_CP074348.1 Lanthipeptides: KHA74_RS03200_lanthipeptide NZ_CP083943.1 Lanthipeptides: LCH16_RS03220_lanthipeptide NZ_CP083943.1 Lanthipeptides: LCH16_RS03220_lanthipeptide NZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10965_lanthipeptide NZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10965_lanthipeptide NZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15475_lanthipeptide NZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15475_lanthipeptide
Lanthipeptides: BAMY6639_RS13800_lanthipeptide
5
G W Y--S K V I G N R G R V C T V T V E C M S V C Q
29
W Y S +G N+G C T+T V E C S C
2
A W Y D I S C K L G N K G A W C T L T V E C Q S S C N
28
with 108 more sequence matches
Only the first 10 are displayed here.
48.3%
NZ_CP025249.1 and 1 other:
NZ_CP025249.1 Lanthipeptides: CWT12_RS00385_lanthipeptide
Lanthipeptides: CWT12_RS00385_lanthipeptide
3
F P G W Y S K V I G N R G R V C T V T V E C M S V C Q
29
F P W S+ +G N G V C T+T E C +C
2
F P-W L S R K L G N T G Y V C T L T K E C Q R M C N
27
48.3%
NZ_FOBE01000018.1:
Lanthipeptides: BMW61_RS13085_lanthipeptide
5
G W Y S K V---I G N R G R V C T V T V E C M S V C Q
29
G W Y S++ +G N R G C T+T E C + C
1
G W Y S E M S A A L G N R G S Y C T L T K E C Q A C C N
28
48.3%
NZ_LR134483.1 and 1 other:
NZ_LR134483.1 Lanthipeptides: EL241_RS01725_lanthipeptide
Lanthipeptides: EL241_RS01725_lanthipeptide
5
G W--Y S K V I G N R G R V C T V T V E C M S V C Q
29
G W S K +G N+G V C T+T E C +C+
2
G W K D L S K S L G N K G Y V C T L T K E C Q K L C R
28
45.5%
NC_018089.1 and 11 others:
NC_018089.1 Lanthipeptides: SMUGS5_RS08725_lanthipeptide NZ_CP044493.1 Lanthipeptides: FSA40_RS09065_lanthipeptide NZ_CP044493.1 Lanthipeptides: FSA40_RS09065_lanthipeptide NZ_CP050270.1 Lanthipeptides: HB753_RS00325_lanthipeptide NZ_CP050270.1 Lanthipeptides: HB753_RS00325_lanthipeptide NZ_JADPAN010000004.1 Lanthipeptides: I4U28_RS03985_lanthipeptide NZ_JADPAN010000004.1 Lanthipeptides: I4U28_RS03985_lanthipeptide NZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS08120_lanthipeptide NZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS08120_lanthipeptide NZ_JAQCYD010000003.1 Lanthipeptides: PGX70_RS05515_lanthipeptide NZ_JAQCYD010000003.1 Lanthipeptides: PGX70_RS05515_lanthipeptide
Lanthipeptides: SMUGS5_RS08725_lanthipeptide
1
T A F P G W Y S K V I G N R G R V C T V T V E C M S V C Q
29
T +S V+G N+G +C T V T V E C M C
4
T V V N S T F S I V L G N K G Y I C T V T V E C M R N C S
32
44.8%
NZ_CP030280.1 and 1 other:
NZ_CP030280.1 Lanthipeptides: DQQ01_RS07655_lanthipeptide
Lanthipeptides: DQQ01_RS07655_lanthipeptide
8
S K V I G N R G R V C T V T V E C M S V C Q
29
S K G N G +C+V T V E C M +C
3
S K D W G N D G Y L C S V T V E C M I I C N
24
44.8%
NZ_CP030280.1 and 3 others:
NZ_CP030280.1 Lanthipeptides: DQQ01_RS07645_lanthipeptide NZ_CP030280.1 Lanthipeptides: DQQ01_RS07650_lanthipeptide NZ_CP030280.1 Lanthipeptides: DQQ01_RS07645_lanthipeptide
Lanthipeptides: DQQ01_RS07650_lanthipeptide
8
S K V I G N R G R V C T V T V E C M S V C Q
29
S K G N G +C+V T V E C M +C
3
S K D W G N D G Y L C S V T V E C M V I C N
24
44.8%
NZ_CP063276.1 and 1 other:
NZ_CP063276.1 Lanthipeptides: IM743_RS02795_lanthipeptide
Lanthipeptides: IM743_RS02795_lanthipeptide
5
G W Y--S K V I G N R G R V C T V T V E C M S V C Q
29
W Y S +G N+G C T+T V E C + C
2
A W Y D V S C R L G N K G A W C T L T V E C Q N N C N
28
44.8%
NZ_KE384107.1:
Lanthipeptides: G586_RS23925_lanthipeptide
5
G W Y S K V---I G N R G R V C T V T V E C M S V C Q
29
G W Y+ + +G N R G C T+T E C + C
1
G W Y A D L S A S L G N R G S Y C T I T K E C Q A C C N
28
44.8%
NZ_LR134483.1 and 1 other:
NZ_LR134483.1 Lanthipeptides: EL241_RS01720_lanthipeptide
Lanthipeptides: EL241_RS01720_lanthipeptide
8
S K V I G N R G R V C T V T V E C M S V C Q
29
S K +G N+G R+C T+T E C S+C
5
S K N L G N K G R I C T L T K E C Q S M C N
26
43.8%
NC_002570.2 and 3 others:
NC_002570.2 Lanthipeptides: AYT26_RS02480_lanthipeptide NZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptide NZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptide
Lanthipeptides: AYT26_RS02480_lanthipeptide
5
G W Y--S K V I G N R G R V C T V T V E C M S V C Q
29
W Y S +G N+G C T+T V E C M C
6
A W Y N I S C R L G N K G A Y C T L T V E C M P S C N
32

#### MIBiG 4.0 matches for HMPREF2804_RS11470

48.3%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
5
G W Y--S K V I G N R G R V C T V T V E C M S V C Q
29
W Y S +G N+G C T+T V E C M C
2
A W Y N I S C R L G N K G A Y C T L T V E C M P S C N
28
33.3%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
8
S K V I G N R G R V C T V T V E C M S V C Q
29
S +G N G C T+T E C C
9
S N A L G N N G G W C T L T K E C Q P N C N
30
12.8%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
18
C T V T V E C M S V C Q
29
C T++ E C C
28
C T L S K E C Q P N C N
39
HMPREF2804_RS11475
Leader:
MMMNVSDLANSIEIDTTPGA
Core:
A D Y A M N S A Q P S M T T P A G V Y A V A E M A V A G S T I C L V C
Core with dehydrations:
A D Y A M N Dha A Q P Dha M Dhb Dhb P A G V Y A V A E M A V A G Dha Dhb I Cys L V Cys

#### antiSMASH-DB 4.0 matches for HMPREF2804_RS11475

100.0%
NZ_KV795763.1 and 1 other:
NZ_KV804818.1 Lanthipeptides: allorf_121741_121908_lanthipeptide
Lanthipeptides: allorf_255073_255240_lanthipeptide
1
A D Y A M N S A Q P S M T T P A G V Y A V A E M A V A G S T I C L V C
35
A D Y A M N S A Q P S M T T P A G V Y A V A E M A V A G S T I C L V C
1
A D Y A M N S A Q P S M T T P A G V Y A V A E M A V A G S T I C L V C
35
17.1%
NZ_CP048812.1:
Lassopeptides: G3568_RS19655_lassopeptide
9
Q P S M T T P A G V Y A V A E M
24
Q P+ T P G+ A
4
Q P N A D T P G G L N N T A N K
19

#### MIBiG 4.0 matches for HMPREF2804_RS11475

28.6%
BGC0000582.4 (ADR72962.1):
Linaridin: cypemycin
21
V A E M A V A G S T I C L V C
35
V A+ + G S T I C L V C
8
V A Q F V I Q G S T I C L V C
22
allorf_109292_109366
Leader:
MLLRNLNFM
Core:
G E I L C G L R G T C R A G F
Core with dehydrations:
G E I L Cys G L R G Dhb Cys R A G F

#### antiSMASH-DB 4.0 matches for allorf_109292_109366

100.0%
NZ_CP054018.1 and 3 others:
NZ_KV804818.1 Lanthipeptides: allorf_109292_109366_lanthipeptide NZ_KV804818.1 Lanthipeptides: allorf_109292_109366_lanthipeptide NZ_KV820076.1 Lanthipeptides: allorf_134599_134673_lanthipeptide
Lanthipeptides: allorf_0084035_0084109_lanthipeptide
1
G E I L C G L R G T C R A G F
15
G E I L C G L R G T C R A G F
1
G E I L C G L R G T C R A G F
15
25.0%
NZ_KB900614.1:
Lanthipeptides: allorf_2952909_2953064_lanthipeptide
4
L C G L R G T C R A G F
15
+C +G C R G F
7
V C A F K G H C R I G F
18
allorf_109330_109521
Leader:
MRFEGNLPRWFLKKHQKNLDAVAQA
Core:
A R L C D S I H V F R L L Y G S G Y L L V Q A A T H I H N D F P K P Q G R L
Core with dehydrations:
A R L Cys D Dha I H V F R L L Y G Dha G Y L L V Q A A Dhb H I H N D F P K P Q G R L

#### antiSMASH-DB 4.0 matches for allorf_109330_109521

100.0%
NZ_KV804818.1 and 1 other:
NZ_KV804818.1 Lanthipeptides: allorf_109330_109521_lanthipeptide
Lanthipeptides: allorf_109330_109521_lanthipeptide
1
A R L C D S I H V F R L L Y G S G Y L L V Q A A T H I H N D F P K P Q G R L
38
A R L C D S I H V F R L L Y G S G Y L L V Q A A T H I H N D F P K P Q G R L
1
A R L C D S I H V F R L L Y G S G Y L L V Q A A T H I H N D F P K P Q G R L
38
18.4%
NZ_NIST01000001.1:
Lassopeptides: CD001_RS25955_lassopeptide
25
T H I H N D F P K P Q G R
37
+H+ N D F P+ G R
1
S H L D N D F P E G T G R
13
15.8%
NZ_JVXR01000038.1:
Lanthipeptides: allorf_10259_10360_lanthipeptide
1
A R L C D S I H
8
A R L C D S+
1
A R L C D S V Q
8
allorf_115697_115819
Leader:
MRVLIYLSVIEAKTSLAR
Core:
W R I P G D I S P E I C G T P R R V L T S T
Core with dehydrations:
W R I P G D I Dha P E I Cys G Dhb P R R V L Dhb Dha Dhb

#### antiSMASH-DB 4.0 matches for allorf_115697_115819

100.0%
NZ_KV804818.1 and 1 other:
NZ_KV804818.1 Lanthipeptides: allorf_115697_115819_lanthipeptide
Lanthipeptides: allorf_115697_115819_lanthipeptide
1
W R I P G D I S P E I C G T P R R V L T S T
22
W R I P G D I S P E I C G T P R R V L T S T
1
W R I P G D I S P E I C G T P R R V L T S T
22
30.0%
NC_018499.1 and 1 other:
NC_018499.1 Lanthipeptides: BCK_RS27825_lanthipeptide
Lanthipeptides: BCK_RS27825_lanthipeptide
5
G D I S P E I C G T P R R V L T
20
G D++P E I T P V T
1
G D V N P E I A P T P H T V T T
16
29.2%
NZ_FUXI01000002.1:
Lanthipeptides: B5D30_RS01240_lanthipeptide
5
G D I S P E I C G T P R R V L T S
21
G D++P+ G+ L T S
1
G D V N P Q T V G S L W E F L T S
17
with 9 more sequence matches
26.7%
NZ_MLKL01000042.1:
Lanthipeptides: BKK45_RS27420_lanthipeptide
5
G D I S P E I C G T P R R V L T
20
G D++P E T P V T
1
G D V N P E T A P T P H T V T T
16
25.0%
NZ_JACIJS010000004.1:
Lanthipeptides: allorf_030388_030501_lanthipeptide
5
G D I S P E I C G T
14
G D+S P +C G
2
G D L S P C V C G A
11
25.0%
NZ_QSIO01000003.1:
Lanthipeptides: DW820_RS07295_lanthipeptide
5
G D I S P E I C G T P R R V L
19
G D I S P E T P V L
1
G D I S P E T--T P A C V L
13
20.0%
NZ_CP075910.1 and 3 others:
NZ_CP075971.1 Lanthipeptides: KLF29_RS14850_lanthipeptide NZ_CP075982.1 Lanthipeptides: KLF51_RS14900_lanthipeptide NZ_CP075994.1 Lanthipeptides: KLF26_RS16110_lanthipeptide
Lanthipeptides: KLF45_RS14835_lanthipeptide
1
W R I P G D I S P E I C G T P R R V L T
20
+ P G ++ E+C G+ L T
6
Y C T P G C L T G E L C G S S E C G L T
25
17.6%
NZ_CABIWO010000014.1:
Lanthipeptides: FY209_RS17155_lanthipeptide
1
W R I P G D I S P E I C G T P R R V L T
20
+ P G ++ ++C G+ L T
5
Y C T P G C V T G Q L C G S S E C G L T
24
17.1%
NC_018499.1 and 1 other:
NC_018499.1 Lanthipeptides: BCK_RS27830_lanthipeptide
Lanthipeptides: BCK_RS27830_lanthipeptide
5
G D I S P E I C G T P
15
G D++P E I P
1
G D V N P E I M S D P
11
15.0%
NZ_JAFHCX010000012.1 and 1 other:
NZ_LR738722.1 Lanthipeptides: STREPSUIS_RS04075_lanthipeptide
Lanthipeptides: JXW96_RS06965_lanthipeptide
5
G D I S P E
10
G D I S P E
1
G D I S P E
6
14.6%
NZ_CP051486.1:
Lanthipeptides: allorf_6974648_6974821_lanthipeptide
2
R I P G D I S P E I C G T
14
R+P G + P C G
10
R V P G R V L P G R C G A
22
10.7%
NC_016582.1:
Lanthipeptides: allorf_10870098_10870307_lanthipeptide
12
C G T P R R V L
19
C G T R R+L
16
C G T S R R L L
23
allorf_115961_116155
Leader:
MVTSATIQVKVCTVGYGFRIHLYRQVKSLYS
Core:
P C L G Q G R V S S P S N L H I I L R P L S M F G V V I R K Y F D
Core with dehydrations:
P Cys L G Q G R V Dha Dha P Dha N L H I I L R P L Dha M F G V V I R K Y F D

#### antiSMASH-DB 4.0 matches for allorf_115961_116155

100.0%
NZ_KV795763.1 and 2 others:
NZ_KV804818.1 Lanthipeptides: allorf_115961_116155_lanthipeptide NZ_KV804818.1 Lanthipeptides: allorf_115961_116155_lanthipeptide
Lanthipeptides: allorf_249293_249487_lanthipeptide
1
P C L G Q G R V S S P S N L H I I L R P L S M F G V V I R K Y F D
33
P C L G Q G R V S S P S N L H I I L R P L S M F G V V I R K Y F D
1
P C L G Q G R V S S P S N L H I I L R P L S M F G V V I R K Y F D
33
24.2%
NZ_BMUN01000001.1 and 9 others:
NZ_CP012382.1 Lanthipeptides: SAM23877_RS36835_lanthipeptide NZ_CP012949.1 Lanthipeptides: SAM40697_RS33360_lanthipeptide NZ_CP027299.1 Lanthipeptides: C1N79_RS34825_lanthipeptide NZ_CP039123.1 Lanthipeptides: E5N77_RS35110_lanthipeptide NZ_CP104697.1 Lanthipeptides: N6Q81_RS33410_lanthipeptide NZ_CP104697.1 Lanthipeptides: N6Q81_RS33410_lanthipeptide NZ_JACWAA010000001.1 Lanthipeptides: ICA23_RS00945_lanthipeptide NZ_KZ195574.1 Lanthipeptides: B9W62_RS39030_lanthipeptide NZ_MQUH01000030.1 Lanthipeptides: BSZ07_RS37165_lanthipeptide
Lanthipeptides: IE238_RS00870_lanthipeptide
3
L G Q G R V S S P S N L H I I L R
19
G Q G +S P S+ I R
3
F G Q G T F T S P S S Y A I G T R
19
24.2%
NZ_CP043959.1 and 8 others:
NZ_CP054939.1 Lanthipeptides: HUT14_RS33610_lanthipeptide NZ_CP104864.1 Lanthipeptides: N7E53_RS01070_lanthipeptide NZ_FKJH01000076.1 Lanthipeptides: STEPF7_RS31605_lanthipeptide NZ_GG657758.1 Lanthipeptides: SSRG_RS36710_lanthipeptide NZ_JMLN01000003.1 Lanthipeptides: BR33_RS35695_lanthipeptide NZ_KL503830.1 Lanthipeptides: DJ64_RS34550_lanthipeptide NZ_VIUV01000001.1 Lanthipeptides: FB570_RS00565_lanthipeptide NZ_WUUF01000042.1 Lanthipeptides: GSE51_RS09870_lanthipeptide
Lanthipeptides: F3L20_RS18420_lanthipeptide
3
L G Q G R V S S P S N L H I I L R
19
G Q G +S P S+ I R
3
F G Q G T Y T S P S S Y A I G T R
19
with 5 more sequence matches
24.2%
NZ_CP058273.1:
Lanthipeptides: AY578_RS00390_lanthipeptide
4
G Q G R V S S P S N L H I I L R
19
G Q G +S P S+ I R
1
G Q G T Y T S P S S Y A I G T R
16
21.2%
NZ_BEWD01000004.1 and 5 others:
NZ_BMVQ01000001.1 Lanthipeptides: IE283_RS00890_lanthipeptide NZ_BMWI01000001.1 Lanthipeptides: IE253_RS05465_lanthipeptide NZ_CP042324.1 Lanthipeptides: FQ762_RS01285_lanthipeptide NZ_GG657756.1 Lanthipeptides: SSPG_RS36720_lanthipeptide NZ_LT629768.1 Lanthipeptides: BLU60_RS01655_lanthipeptide
Lanthipeptides: Sru02f_RS16280_lanthipeptide
3
L G Q G R V S S P S N L H I I L R
19
G+G +S P S+ I R
3
F G E G T F T S P S S Y A I G T R
19
21.2%
NZ_CP023699.1:
Lassopeptides: CP970_RS43860_lassopeptide
19
R P L S M F G V V I R
29
R P L F G+ I R
5
R P L D S F G L N I R
15
20.0%
NZ_CP067396.1:
Lanthipeptides: JHW41_RS12400_lanthipeptide
9
S S P S N L H I I L R P L S M
23
+ P S H +L R L S M
8
T G P S G A H G L L R C L S M
22
13.3%
NZ_CP078093.1:
Lanthipeptides: KVH43_RS13030_lanthipeptide
15
H I I L R P L S M F G V V I R K Y
31
+ + P L+ + V+ R K Y
1
N W T M N P L T C Y T V L S R K Y
17
allorf_117600_117668
Leader:
MSPYFQDLSLIHAA
Core:
L Q T C L T K S
Core with dehydrations:
L Q Dhb Cys L Dhb K Dha

#### antiSMASH-DB 4.0 matches for allorf_117600_117668

100.0%
NZ_KV795763.1 and 2 others:
NZ_KV804818.1 Lanthipeptides: allorf_117600_117668_lanthipeptide NZ_KV804818.1 Lanthipeptides: allorf_117600_117668_lanthipeptide
Lanthipeptides: allorf_250932_251000_lanthipeptide
1
L Q T C L T K S
8
L Q T C L T K S
1
L Q T C L T K S
8
allorf_117642_117731
Leader:
MFTLSGLNAWSGS
Core:
F L L I Y S F H L A F C K T C L
Core with dehydrations:
F L L I Y Dha F H L A F Cys K Dhb Cys L

#### antiSMASH-DB 4.0 matches for allorf_117642_117731

100.0%
NZ_KV795763.1 and 2 others:
NZ_KV804818.1 Lanthipeptides: allorf_117642_117731_lanthipeptide NZ_KV804818.1 Lanthipeptides: allorf_117642_117731_lanthipeptide
Lanthipeptides: allorf_250974_251063_lanthipeptide
1
F L L I Y S F H L A F C K T C L
16
F L L I Y S F H L A F C K T C L
1
F L L I Y S F H L A F C K T C L
16
23.1%
NC_014483.2 and 18 others:
NC_014622.2 Lanthipeptides: PPSC2_RS36205_lanthipeptide NC_017542.1 Lanthipeptides: PPM_RS07465_lanthipeptide NZ_CP006872.1 Lanthipeptides: PPSQR21_RS07740_lanthipeptide NZ_CP023711.1 Lanthipeptides: CPY53_RS22235_lanthipeptide NZ_CP025957.1 Lanthipeptides: C1A50_RS07530_lanthipeptide NZ_CP029370.1 Lanthipeptides: DI243_RS07495_lanthipeptide NZ_CP040829.1 Lanthipeptides: FGY93_RS00500_lanthipeptide NZ_CP049598.1 Lanthipeptides: G7L40_RS00115_lanthipeptide NZ_CP073682.1 Lanthipeptides: KAI36_RS07745_lanthipeptide NZ_CP084033.1 Lanthipeptides: LAZ93_RS07550_lanthipeptide NZ_CP085682.1 Lanthipeptides: LJR53_RS07370_lanthipeptide NZ_CP086373.1 Lanthipeptides: LMH85_RS07780_lanthipeptide NZ_CP092779.1 Lanthipeptides: MJ749_RS07440_lanthipeptide NZ_CP097766.1 Lanthipeptides: MF620_RS07485_lanthipeptide NZ_CP102865.1 Lanthipeptides: NWS42_RS21195_lanthipeptide NZ_JAKVDC010000001.1 Lanthipeptides: MKN04_RS02755_lanthipeptide NZ_JWJJ01000002.1 Lanthipeptides: U707_RS10390_lanthipeptide NZ_POVT01000009.1 Lanthipeptides: C1T20_RS05900_lanthipeptide
Lanthipeptides: PPE_RS07020_lanthipeptide
7
F H L A F C K T C
15
L+F C K T C
18
V S L S F C K T C
26
23.1%
NC_023037.2 and 11 others:
NZ_CP017967.2 Lanthipeptides: PPYC1_RS07755_lanthipeptide NZ_CP017968.3 Lanthipeptides: PPYC2_RS08330_lanthipeptide NZ_CP061172.1 Lanthipeptides: IAQ67_RS07480_lanthipeptide NZ_CP073683.1 Lanthipeptides: KAI37_RS07495_lanthipeptide NZ_CP109848.1 Lanthipeptides: OF859_RS22650_lanthipeptide NZ_CP113973.1 Lanthipeptides: OYT09_RS07785_lanthipeptide NZ_FOYG01000001.1 Lanthipeptides: BM358_RS03525_lanthipeptide NZ_JAAMNR010000001.1 Lanthipeptides: G9G54_RS03500_lanthipeptide NZ_PNXQ01000013.1 Lanthipeptides: C1I60_RS14430_lanthipeptide NZ_POVS01000009.1 Lanthipeptides: C1T21_RS10630_lanthipeptide NZ_PTJM01000020.1 Lanthipeptides: C5G87_RS02825_lanthipeptide
Lanthipeptides: X809_RS07820_lanthipeptide
7
F H L A F C K T C
15
L F C K T C
18
V S L T F C K T C
26
with 3 more sequence matches
19.2%
NZ_JAIFIS010000001.1:
Lanthipeptides: K1X09_RS26315_lanthipeptide
7
F H L A F C K T C
15
L+F C+T C
18
I S L S F C R T C
26
18.6%
NZ_QKUF01000009.1:
Lanthipeptides: allorf_200737_200904_lanthipeptide
2
L L I Y S F H L A F C K T C
15
L L I S F F C+ C
24
L L I R S F S Y N F C R Q C
37
11.8%
NZ_BOSN01000007.1 and 3 others:
NZ_BOSN01000007.1 Lanthipeptides: allorf_257698_257880_lanthipeptide NZ_JAHHXV010000040.1 Lanthipeptides: allorf_13614_13796_lanthipeptide NZ_JAHHXV010000040.1 Lanthipeptides: allorf_13614_13796_lanthipeptide
Lanthipeptides: allorf_257698_257880_lanthipeptide
4
I Y S F H L A F C K T C
15
+Y S F++ C T C
16
L Y S F Y I H K C S T C
27

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.67 out of 26.06
Confidence: medium
BldD
Description: Development and antibiotic global regulator
Species: Streptomyces coelicolor
Score: 21.09 out of 23.43
Confidence: medium
GnfM
Description: Regulator of nitrogen-fixation genes
Species: Geobacter sulfurreducens PCA
Score: 21.52 out of 27.55
Confidence: medium
AfsQ1
Description: Two-component system AfsQ1-Q2, activator of antibiotic production
Species: Streptomyces coelicolor
Score: 17.68 out of 19.52
Confidence: medium
CcpA
Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 17.78 out of 20.97
Confidence: medium
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 21.73 out of 27.78
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.60 out of 26.06
Confidence: medium
IolR
Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 20.06 out of 23.79
Confidence: medium
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 21.20 out of 27.78
Confidence: medium
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.98 out of 28.19
Confidence: medium
Additional weak hits (16):
RicR
Description: Copper-responsive regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 22.56 out of 32.93
Confidence: weak
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 20.74 out of 26.06
Confidence: weak
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.11 out of 26.06
Confidence: weak
LuxO
Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 20.70 out of 26.12
Confidence: weak
PerR
Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 20.41 out of 28.14
Confidence: weak
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 22.95 out of 29.38
Confidence: weak
PerR
Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 22.59 out of 28.14
Confidence: weak
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 20.02 out of 26.06
Confidence: weak
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 20.06 out of 26.06
Confidence: weak
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 19.53 out of 26.06
Confidence: weak
ClgR
Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 22.25 out of 30.22
Confidence: weak
CopR
Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 20.61 out of 30.97
Confidence: weak
NuR
Description: Nickel-responsive regulator
Species: Streptomyces coelicolor
Score: 23.40 out of 30.98
Confidence: weak
HypR
Description: L-hydroxyproline utilization repressor
Species: Streptomyces coelicolor
Score: 18.79 out of 22.40
Confidence: weak
RicR
Description: Copper-responsive regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 24.31 out of 32.93
Confidence: weak
ZuR variant 2
Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 21.52 out of 33.14
Confidence: weak
Lanthipeptides
TFBS Finder
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

HMPREF2804_RS11135 - Class II
  Cleavage pHMM score: -6.20
  RODEO score: 0
  Monoisotopic mass: 3348.6 Da
  Molecular weight: 3350.8 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3368.8 Da N = 1
    3386.8 Da N = 2
    3404.8 Da N = 3
    3422.8 Da N = 4
HMPREF2804_RS09455 - Class II
  Cleavage pHMM score: -6.80
  RODEO score: 0
  Monoisotopic mass: 2632.4 Da
  Molecular weight: 2634.2 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2652.2 Da N = 1
allorf_083218_083325 - Class II
  Cleavage pHMM score: -6.60
  RODEO score: 0
  Monoisotopic mass: 2930.5 Da
  Molecular weight: 2932.4 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2950.4 Da N = 1
allorf_096778_096948 - Class II
  Cleavage pHMM score: -7.30
  RODEO score: 0
  Monoisotopic mass: 4976.4 Da
  Molecular weight: 4979.7 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    4997.8 Da N = 1
    5015.8 Da N = 2
    5033.8 Da N = 3
    5051.8 Da N = 4
    5069.8 Da N = 5
    5087.9 Da N = 6
allorf_097220_097294 - Class II
  Cleavage pHMM score: -7.20
  RODEO score: 0
  Monoisotopic mass: 1357.7 Da
  Molecular weight: 1358.7 Da
  Number of bridges: 1
HMPREF2804_RS09455 - Class II
  Cleavage pHMM score: -6.80
  RODEO score: 0
  Monoisotopic mass: 2632.4 Da
  Molecular weight: 2634.2 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2652.2 Da N = 1
HMPREF2804_RS09475 - Class II
  Cleavage pHMM score: -0.60
  RODEO score: 0
  Monoisotopic mass: 3513.4 Da
  Molecular weight: 3515.5 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3533.6 Da N = 1
    3551.6 Da N = 2
HMPREF2804_RS11470 - Class II
  Cleavage pHMM score: -0.60
  RODEO score: 0
  Monoisotopic mass: 3100.5 Da
  Molecular weight: 3102.6 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3120.6 Da N = 1
    3138.7 Da N = 2
allorf_096778_096948 - Class II
  Cleavage pHMM score: -7.30
  RODEO score: 0
  Monoisotopic mass: 4976.4 Da
  Molecular weight: 4979.7 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    4997.8 Da N = 1
    5015.8 Da N = 2
    5033.8 Da N = 3
    5051.8 Da N = 4
    5069.8 Da N = 5
    5087.9 Da N = 6
allorf_097220_097294 - Class II
  Cleavage pHMM score: -7.20
  RODEO score: 0
  Monoisotopic mass: 1357.7 Da
  Molecular weight: 1358.7 Da
  Number of bridges: 1
allorf_109292_109366 - Class II
  Cleavage pHMM score: -4.80
  RODEO score: 0
  Monoisotopic mass: 1533.8 Da
  Molecular weight: 1534.8 Da
  Number of bridges: 1
allorf_109330_109521 - Class II
  Cleavage pHMM score: -3.80
  RODEO score: 0
  Monoisotopic mass: 4251.3 Da
  Molecular weight: 4253.9 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    4271.9 Da N = 1
    4289.9 Da N = 2
allorf_115697_115819 - Class II
  Cleavage pHMM score: -6.80
  RODEO score: 0
  Monoisotopic mass: 2363.3 Da
  Molecular weight: 2364.7 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2382.7 Da N = 1
    2400.7 Da N = 2
    2418.8 Da N = 3
    2436.8 Da N = 4
allorf_115961_116155 - Class II
  Cleavage pHMM score: -5.20
  RODEO score: 0
  Monoisotopic mass: 3627.0 Da
  Molecular weight: 3629.3 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3647.3 Da N = 1
    3665.3 Da N = 2
    3683.3 Da N = 3
allorf_117600_117668 - Class II
  Cleavage pHMM score: -5.40
  RODEO score: 0
  Monoisotopic mass: 838.5 Da
  Molecular weight: 839.0 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    857.0 Da N = 1
    875.0 Da N = 2
allorf_117642_117731 - Class II
  Cleavage pHMM score: -7.00
  RODEO score: 0
  Monoisotopic mass: 1882.0 Da
  Molecular weight: 1883.3 Da
  Number of bridges: 2
HMPREF2804_RS09455 - Class II
  Cleavage pHMM score: -6.80
  RODEO score: 0
  Monoisotopic mass: 2602.4 Da
  Molecular weight: 2604.2 Da
  Number of bridges: 0
  Additional modifications: AviCys
  Additional modifications: OH
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2622.2 Da N = 1
HMPREF2804_RS09475 - Class II
  Cleavage pHMM score: -0.60
  RODEO score: 0
  Monoisotopic mass: 3483.4 Da
  Molecular weight: 3485.5 Da
  Number of bridges: 1
  Additional modifications: AviCys
  Additional modifications: OH
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3503.6 Da N = 1
    3521.6 Da N = 2
HMPREF2804_RS11470 - Class II
  Cleavage pHMM score: -0.60
  RODEO score: 0
  Monoisotopic mass: 3070.5 Da
  Molecular weight: 3072.6 Da
  Number of bridges: 2
  Additional modifications: AviCys
  Additional modifications: OH
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3090.6 Da N = 1
    3108.7 Da N = 2
HMPREF2804_RS11475 - Class II
  Cleavage pHMM score: -1.80
  RODEO score: 0
  Monoisotopic mass: 3354.6 Da
  Molecular weight: 3356.9 Da
  Number of bridges: 1
  Additional modifications: AviCys
  Additional modifications: OH
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3374.9 Da N = 1
    3392.9 Da N = 2
    3410.9 Da N = 3
    3429.0 Da N = 4
allorf_109292_109366 - Class II
  Cleavage pHMM score: -4.80
  RODEO score: 0
  Monoisotopic mass: 1503.8 Da
  Molecular weight: 1504.8 Da
  Number of bridges: 0
  Additional modifications: AviCys
  Additional modifications: OH
allorf_109330_109521 - Class II
  Cleavage pHMM score: -3.80
  RODEO score: 0
  Monoisotopic mass: 4221.3 Da
  Molecular weight: 4223.9 Da
  Number of bridges: 0
  Additional modifications: AviCys
  Additional modifications: OH
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    4241.9 Da N = 1
    4259.9 Da N = 2
allorf_115697_115819 - Class II
  Cleavage pHMM score: -6.80
  RODEO score: 0
  Monoisotopic mass: 2333.3 Da
  Molecular weight: 2334.7 Da
  Number of bridges: 0
  Additional modifications: AviCys
  Additional modifications: OH
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2352.7 Da N = 1
    2370.7 Da N = 2
    2388.8 Da N = 3
    2406.8 Da N = 4
allorf_115961_116155 - Class II
  Cleavage pHMM score: -5.20
  RODEO score: 0
  Monoisotopic mass: 3597.0 Da
  Molecular weight: 3599.3 Da
  Number of bridges: 0
  Additional modifications: AviCys
  Additional modifications: OH
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3617.3 Da N = 1
    3635.3 Da N = 2
    3653.3 Da N = 3
allorf_117600_117668 - Class II
  Cleavage pHMM score: -5.40
  RODEO score: 0
  Monoisotopic mass: 808.5 Da
  Molecular weight: 809.0 Da
  Number of bridges: 0
  Additional modifications: AviCys
  Additional modifications: OH
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    827.0 Da N = 1
    845.0 Da N = 2
allorf_117642_117731 - Class II
  Cleavage pHMM score: -7.00
  RODEO score: 0
  Monoisotopic mass: 1852.0 Da
  Molecular weight: 1853.3 Da
  Number of bridges: 1
  Additional modifications: AviCys
  Additional modifications: OH

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
AfsQ1 | Two-component system AfsQ1-Q2, activator of antibiotic production
BldD | Development and antibiotic global regulator
CcpA | Catabolite control protein A
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
GnfM | Regulator of nitrogen-fixation genes
IolR | Regulator of the inositol catabolism
MogR | Repressor of flagellar motility genes
ZuR variant 1 | Zinc-responsive repressor