LOCUS       NZ_KV802690            22553 bp    DNA     linear   CON 08-NOV-2024
DEFINITION  Streptococcus sp. HMSC073F11 Scaffold211, whole genome shotgun
            sequence.
ACCESSION   NZ_KV802690
VERSION     NZ_KV802690.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptococcus sp. HMSC073F11
  ORGANISM  Streptococcus sp. HMSC073F11
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 833953)
  AUTHORS   Mitreva,M., Pepin,K.H., Mihindukulasuriya,K.A., Fulton,R.,
            Fronick,C., O'Laughlin,M., Miner,T., Herter,B., Rosa,B.A.,
            Cordes,M., Tomlinson,C., Wollam,A., Palsikar,V.B., Mardis,E.R. and
            Wilson,R.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2016) McDonnell Genome Institute, Washington
            University School of Medicine, 4444 Forest Park, St. Louis, MO
            63108, USA
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: High-Quality Draft
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: Velvet v. 1.1.06
            Genome Coverage                   :: 213x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001810785.1-RS_2024_11_05
            Annotation Date                   :: 11/05/2024 23:57:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,892
            CDSs (total)                      :: 1,845
            Genes (coding)                    :: 1,788
            CDSs (with protein)               :: 1,788
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 16 of 57
            Pseudo Genes (incomplete)         :: 34 of 57
            Pseudo Genes (internal stop)      :: 10 of 57
            Pseudo Genes (multiple problems)  :: 3 of 57
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:06:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 328153
            Orig. end                         :: 350706
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KV802690.1.
            The WUSC is a large strain collection isolated from clinical
            samples. Each sample is associated with metadata, including source,
            isolation site, 16s rRNA, metabolic, and other phenotypic
            information. The goal is to sample an adequate number of important,
            yet minor species, further adding to the catelogue of sequenced
            bacterial genomes and improving the diversity of the genomes
            available to the public. WGS will be preformed on approximely 550
            isolates. Samples were selected based on RDP analysis at the genus
            level. This is a reference genomes for the Human Microbiome Project
            and the work was funded by the National Institutes of Health (NIH)
            grant U54 HG004968.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22553
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RaS-RiPP"
                     /product="sactipeptide"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..22553
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="chemical_hybrid"
                     /product="RaS-RiPP"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..22553
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12553](+)"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12553
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     misc_feature    492..506
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.86"
                     /tool="antismash"
     gene            733..1542
                     /locus_tag="HMPREF2764_RS10365"
     CDS             733..1542
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HMPREF2764_RS10365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="helicase HerA-like domain-containing protein"
                     /protein_id="WP_315940704.1"
                     /transl_table=11
                     /translation="MKQGLTGPYVKIGKSVNVVERELNQLTSNDKDFDLSLLSEQIANE
                     TTQQTNSGVYKADAFNFGINQYLIQKVNYKLANTNFKTFFSSQKENLLDIIKNFATTSK
                     KSLYIDASRIGTTDGIGGMIIDLVTNFLLNIPKNEINSFVIFIDEVHRYTKSNNIGETS
                     FYTGLTGIAREGRKKGIFLFLTTQNPNDVDKILLGQIGTLLIHRLTAIDEIRAISNHLS
                     EQQIAQVRKLNTGEAVLTSINLLKDLYLEIEKCDRVHMNDTPSLWQD"
     protocluster    1198..22553
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[11197:12553](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      11198..12553
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="2"
     misc_feature    1802..1816
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 19.31"
                     /tool="antismash"
     gene            1923..2285
                     /locus_tag="HMPREF2764_RS03250"
                     /old_locus_tag="HMPREF2764_03260"
     CDS             1923..2285
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851909.1"
                     /locus_tag="HMPREF2764_RS03250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2764_03260"
                     /product="SAG1252 family conjugative relaxosome accessory
                     protein"
                     /protein_id="WP_070496571.1"
                     /transl_table=11
                     /translation="MTDQYRIIRKEINLTPEELEQIQKLMKQEHVEQFSPFVRQKLLDA
                     IEGRKSMTDWFTLWQYQKMEQISRDILQVTILAEQSHQVTAEHLRIILTCVQELIAEVN
                     QTIPLSQDFRDKYMGG"
     gene            2288..2653
                     /gene="mobC"
                     /locus_tag="HMPREF2764_RS03255"
                     /old_locus_tag="HMPREF2764_03265"
     CDS             2288..2653
                     /codon_start=1
                     /gene="mobC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /locus_tag="HMPREF2764_RS03255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2764_03265"
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="WP_023026929.1"
                     /transl_table=11
                     /translation="MENRYRTNLKKVFLTDQELATLYDRIGQSRCKNFSAYARKVLLNP
                     NMTFLTIDTSNYEDLVFELKRIGNNLNQIARTVNQTHILKPCDRELLVQGIGQLIKEVE
                     SDFNIKCQQLKEFYGSH"
     gene            2640..4514
                     /locus_tag="HMPREF2764_RS03260"
                     /old_locus_tag="HMPREF2764_03270"
     CDS             2640..4514
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261812.1"
                     /locus_tag="HMPREF2764_RS03260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2764_03270"
                     /product="SAG1250 family conjugative relaxase"
                     /protein_id="WP_070496572.1"
                     /transl_table=11
                     /translation="MVVTKHFAVHSTKYRKSLIKYILNPEKTEQLKLVSDFGMRNYLVF
                     PSYEEMVDMYEANLTNNDRLYDSRNDRQQVKQTKIHAHHLIQSFSPDDKLTPEEINRIG
                     YETIKELTGGNFRFIVTTHTDRNHVHNHILINSVDLNSDKKLKWDYAQERNLRMISDRL
                     AKEAGATIIQPNRYSHEKFEAYRKTNHKFELKQRLYFLMKHSKNFEDFLAKAPALNVEM
                     DFSHKHARFLMTDREMKQVIRGKQLDKRQPYTEDYFREQFATRAIEQRLDFLLPRARDL
                     SHLLEMAEQLNLTISLKKKHVTFTLTENGRTISIENKKVSTKNLYDVQFFEDYFDQRES
                     ITESDLTNFVYDLKTYQEDQDKDKLSSEELLTAYKEFKEKHDQIQEFEVVLAEYQIDKV
                     VKEGLFITMNYGVKKDGLVFIPNRNLDIHENEQDKSYHVFIRETAQFFIFNKESSDLNR
                     YMRGRELIRQLTHDSTHIPKRRRPTIANLKEKIAEVNLLIELDLNNQSYQEIKDELIKE
                     IAQLDLTITDLQDKVAHLNKVAEVLINLNNSDPENRRLAKYDYAKMNLTSAIKLEQVEK
                     EIEENQRFMTKWIDDYEYKIRRLENFINILDNTRNQNVTKLERETKSV"
     gene            complement(4620..5483)
                     /locus_tag="HMPREF2764_RS03265"
                     /old_locus_tag="HMPREF2764_03275"
     CDS             complement(4620..5483)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /locus_tag="HMPREF2764_RS03265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2764_03275"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_070496573.1"
                     /transl_table=11
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSAD
                     LLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDNLEYIYRIEIERSTF
                     LTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFYSLV
                     GREQEYEANYSHLMELYQTKDFEHQEYLFGYIRVRYNYAHYLVSKEKYNEAIQEALETI
                     ELCKQRQTSYQLAPLLILVGNAGAKFLDKEQVKNYYIEAKELCKIYNNPLMLMKIENYL
                     KELDTV"
     gene            5678..5848
                     /locus_tag="HMPREF2764_RS10265"
                     /old_locus_tag="HMPREF2764_03280"
     CDS             5678..5848
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /locus_tag="HMPREF2764_RS10265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2764_03280"
                     /product="PhrA family quorum-sensing system peptide"
                     /protein_id="WP_061390890.1"
                     /transl_table=11
                     /translation="MRKKCGIKKLVTFALLGVFMFSNTIPYQQFIQKNKQLEIRVQSQK
                     KSNGLDVGKAD"
     misc_feature    complement(5680..5695)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            6013..6306
                     /locus_tag="HMPREF2764_RS03275"
                     /old_locus_tag="HMPREF2764_03285"
     CDS             6013..6306
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748217.1"
                     /locus_tag="HMPREF2764_RS03275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2764_03285"
                     /product="hypothetical protein"
                     /protein_id="WP_070496574.1"
                     /transl_table=11
                     /translation="MKKSIKKIITTSLLALTLAGAGGSIVSAATVWYKGTAVYWNYGRT
                     AGLWSYSNVQSGVYEHSASANGAFSGWRSPGVEARASRFIGTGTAECYWNCR"
     gene            6313..8514
                     /locus_tag="HMPREF2764_RS03280"
                     /old_locus_tag="HMPREF2764_03290"
     CDS             6313..8514
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221426.1"
                     /locus_tag="HMPREF2764_RS03280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2764_03290"
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_070527129.1"
                     /transl_table=11
                     /translation="MTYKNMLLGKMKYLILFLIAIQSILLALVAIFLAGLQYQQSWQSY
                     NHHSGTVTVYLQKLTEEQSQDVFNYFLEQSDLSIWTKRSESSDTGEGPNRIYIDILGSS
                     AGFSDFESTGKIVVSQQQFANLLSHSDNSMTIGLDKGSNNMLYELPDLLFSTPVVIERL
                     DYTFQNTNTINGIYHINGLHDAVSRDNFLLHLSKVSGISVEDLTKESFGSSTDQGIWGI
                     ILAISILVNAFILLILFLICVLQSFKHFGTLILLGWDRKELWSAFFKNSLLFSIYTIPI
                     ISLCSWLLSGWSSFGLSSFILVFAGVSLSVLLLLFIFIIPTIIVYSVSPLAAIHKRLPM
                     KPLMVTCLLFYTLVAGLLIAVSYSLDAPMNQFIDNMKVSREWKNVEDMYVISRFVEGDD
                     VGTYAGTTNSLERSMYNFYQRISELPGVYIAQGQFLNQESLDAVYGTYQHVPKKPFWYL
                     KFSYNYLQDLGIPLSDEELLEMRNGTRLYLLPNTLNTEELEVMKAYLQESVTVKPGDLQ
                     TNFTENQKFMFKVYQPSRPIFTWSDSISYGTTSENPVIFVSTPENLYFMESANLVVSGY
                     NGLLKIRDRETMEQVVSVLETEFPDLTDNRLSFTTVKNFINGLQKDLSYTFYLFGTIIA
                     IIIITMMAIFWSFVLMYRLLFEEKLYVQYFMGFSPWKRYIGVLSLIISFSVVELIVSIL
                     VGSKLGIVMTLATFAFQIMLLYFSLFRKEGESIIQLFKE"
     gene            8519..9175
                     /locus_tag="HMPREF2764_RS03285"
                     /old_locus_tag="HMPREF2764_03295"
     CDS             8519..9175
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087001.1"
                     /locus_tag="HMPREF2764_RS03285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2764_03295"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_033685029.1"
                     /transl_table=11
                     /translation="MSRISVQNVSKQFGSREIFKDLSFDIEENEFVALVGPSGSGKSTI
                     LNMIGLLDTVDSGKILINGKVLPKVNSQSAVHYRRNVINYLFQSNALISTSSVKDNLML
                     AMTFSNFSRQEKEQRIKETLEFVGLQNRLNSKINELSGGEQQRIAIVRAILKPGDIVLA
                     DEPTGSLDPEMSQKAFDLIRTLRDQFGKTILVVTHNMEQARQCDRIISLESVLVN"
     gene            9244..9522
                     /locus_tag="HMPREF2764_RS03290"
                     /old_locus_tag="HMPREF2764_03300"
     CDS             9244..9522
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /locus_tag="HMPREF2764_RS03290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2764_03300"
                     /product="competence protein ComA"
                     /protein_id="WP_070496577.1"
                     /transl_table=11
                     /translation="MKKFTYDIIKQPSVSNRLELKTHVLVENHIDDVICLYIIASNKLL
                     DMVILNPFQKKTIFIPCYFEEDIVKVKDDYEIEWDLLEFQKFRAFLA"
     gene            10001..10858
                     /locus_tag="HMPREF2764_RS03295"
                     /old_locus_tag="HMPREF2764_03305"
     CDS             10001..10858
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /locus_tag="HMPREF2764_RS03295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2764_03305"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_070496578.1"
                     /sec_met_domain="TIGR01716 (E-value: 2.1e-41, bitscore:
                     137.6, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLGQILKKIREAKGLSLYNVANDEISTSQLSRFENGYTDITLS
                     KLLSVLKTLDVSLEEFMYLGRGFHKMSNFEVIDKINNYFYKNNSPALRRLLINCTEKEK
                     EKLSKKLTIILIKLKLQEIEKDNIVTSEEIDFISDYLFSIDIWGEYELELFSSTMEIFC
                     QSSIMILTKEMVRRTDFYKYLPTHRRLITSMLFNAFSLSVERNNIVDASYYREQLVQLF
                     FDETELYERLVFHLIDSCYNFKMTNELSNILEMRKCIGFLKTLESMNLVDRWEKYIERV
                     LNSN"
     gene            10956..11126
                     /locus_tag="HMPREF2764_RS03300"
                     /old_locus_tag="HMPREF2764_03310"
     CDS             10956..11126
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004633836.1"
                     /locus_tag="HMPREF2764_RS03300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2764_03310"
                     /product="subtilosin A family bacteriocin"
                     /protein_id="WP_023026921.1"
                     /transl_table=11
                     /translation="MIKNNKIDNPSVKIEKATVVNNKGCSVCAIGAVCLADGPIPDFEI
                     AGVSAVFTAFG"
     CDS_motif       10956..10997
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MIKNNKIDNPSVKI"
                     /locus_tag="HMPREF2764_RS03300_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10998..11126
                     /prepeptide="core"
                     /locus_tag="HMPREF2764_RS03300_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="26.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="EKATVVNNKGCSVCAIGAVCLADGPIPDFEIAGVSAVFTAFG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MIKNNKIDNPSVKI"
                     /leader_location="[10955:10997](+)"
     aSDomain        11198..11467
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HMPREF2764_RS03305_Subtilosin_rSAM_RR
                     E.1"
                     /evalue="4.60E-21"
                     /identifier="RREFam018.1"
                     /label="HMPREF2764_RS03305"
                     /locus_tag="HMPREF2764_RS03305"
                     /protein_end="90"
                     /protein_start="0"
                     /score="66.0"
                     /tool="antismash"
                     /translation="MYLVLDNQVTIYQTKGDYNVIVEKIDANKRKQFDYFTVNKTGKLL
                     LEAINGKQNMEEFIENFIDTYNLVEDDRSWIETFLNEMMKKGAIA"
     gene            11198..12553
                     /locus_tag="HMPREF2764_RS03305"
                     /old_locus_tag="HMPREF2764_03315"
     CDS             11198..12553
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.5"
                     /locus_tag="HMPREF2764_RS03305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2764_03315"
                     /product="radical SAM protein"
                     /protein_id="WP_070496579.1"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 1.3e-19,
                     bitscore: 66.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="subtilosin (E-value: 4.4e-96, bitscore:
                     317.5, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.4e-07, bitscore: 26.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 5.3e-36, bitscore:
                     120.0, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.7e-16, bitscore: 56.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.3e-07, bitscore: 25.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 6.8e-09, bitscore: 31.1,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.5e-07, bitscore: 27.5,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYLVLDNQVTIYQTKGDYNVIVEKIDANKRKQFDYFTVNKTGKLL
                     LEAINGKQNMEEFIENFIDTYNLVEDDRSWIETFLNEMMKKGAIAIKESPEIANLPLYI
                     YGNSRLISPLHVTVEITEKCNLYCAHCYLNASCNKTTAIDYEGFKSLVKKLKASNVLSI
                     EITGGEVFMNKDAEKILELAFNEFSRVALLTNGTILKKSSLSLLEKNKDKLVMSISLDS
                     VREELHDKFRGMRGSFRSTCKNIRRLTEAGIHVRVASSIFDENMWEVDKLAELAIELGA
                     ELFVYNFVENFGRGTDFNKNSSTKFSKEYSRYLSETVFKYRALIPIIESEDYLKSSSNC
                     GAGTNTILIGADGNLRPCPIFPKNKIFKNINDGSMEEIFSDDVYQKISNIYPPSDENGC
                     SKSCPNYSNCFGCYMKGLESNVDKAPEQYCSWITYNKLEKFMEQYKGGKVIE"
     gene            12546..13466
                     /locus_tag="HMPREF2764_RS03310"
                     /old_locus_tag="HMPREF2764_03320"
     CDS             12546..13466
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HMPREF2764_RS03310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HMPREF2764_03320"
                     /product="hypothetical protein"
                     /protein_id="WP_070496583.1"
                     /transl_table=11
                     /translation="MSNYLFSYKYYRPIPNLFIKQKLREIHKLLKDDLIKFGIENGIII
                     SIFALGCNGRMTEIIYIKSMYRISEDKIYDMLNFLYNKEIELYKVVKDDNINCTISCCG
                     VTANASIPTKESLGYFLKNFLKWENYSVKKYSRVKLETTENIIIKEGELTYVGFLCDNI
                     EIKELGDMLSAKLLEEIFKSQNSVLTEIRNQGLCYTTVSKFHEDLNVVYIGLITSYSKD
                     KISRLDTMYTNVQLTEGEFELAKCRLKKEIIFSTTLYQIDHYLLPFQLLKIDANVSTLL
                     EIIDKIKFEDIVKIFNSRRIVCLKA"
     gene            13481..14329
                     /locus_tag="HMPREF2764_RS03315"
                     /old_locus_tag="HMPREF2764_03325"
     CDS             13481..14329
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HMPREF2764_RS03315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HMPREF2764_03325"
                     /product="hypothetical protein"
                     /protein_id="WP_070496585.1"
                     /transl_table=11
                     /translation="MEKDCTFFIKPVSDLGEVTIERIIFNFNGSIREGYLHLLEHLWVR
                     ANKSWFDDYESKMNIFNALTNKNRITFILVYTESTVNTNKLIFDLNFNEQDFLIEKKTI
                     YEERKLYSDSTPDVDIVLGSLRTIEAFDLTVLKNMMHQMNYKKIRFHFSSKNNGKYMKN
                     PTININKYSIIWKDSNTIQLIDFYDYKVLLTILKVFKITNDNFCFNVNEAKGNYEITFD
                     DYEVFDFMLKNKDNVLMRYQLLLTNTQLFIEQTTYLFDLFGFNFDILDFWREFNWEVLE
                     K"
     gene            15122..15814
                     /locus_tag="HMPREF2764_RS03325"
                     /old_locus_tag="HMPREF2764_03330"
     CDS             15122..15814
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.5"
                     /locus_tag="HMPREF2764_RS03325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2764_03330"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_070496589.1"
                     /transl_table=11
                     /translation="MTTLLELKKLNFAYFKNSKILDNIDLILNQNKIYGLIGKNGAGKT
                     TFIKTLSSVFNNNVFTLEYFKFFDKEVQLSSEFYRQNKFTVFTESESFLNWTFLQYLEM
                     VCQLYNCSIERKRLEFLVNGFKFEEYCKKEIRDLSTGNKKKVFLIVGLYLRRPLLILDE
                     PFDGLDFESTEFLYKMLLEYKQYGTVLLSTHFAESVVRVCDYLYILENAHINLFQGNVS
                     EWLESIRK"
     misc_feature    complement(17363..17379)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.1"
                     /tool="antismash"
     gene            18213..18434
                     /locus_tag="HMPREF2764_RS03335"
                     /old_locus_tag="HMPREF2764_03340"
     CDS             18213..18434
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /locus_tag="HMPREF2764_RS03335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2764_03340"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_048789078.1"
                     /transl_table=11
                     /translation="MYRRLRDLREDHDLTQKQIAEILSFTNSAYAKIERGEHTLTADVL
                     VTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            18740..19009
                     /locus_tag="HMPREF2764_RS03340"
                     /old_locus_tag="HMPREF2764_03345"
     CDS             18740..19009
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397754.1"
                     /locus_tag="HMPREF2764_RS03340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2764_03345"
                     /product="DUF3173 family protein"
                     /protein_id="WP_000450956.1"
                     /transl_table=11
                     /translation="METVNYKDLVAIGFPEHTSRNIIRQAKKIAVKKFEEARKNDKNAV
                     QLGCSPFDNKRLGIAPKNIVENLIGISFSDIEGEKNGYIKDKEI"
     gene            18981..20168
                     /locus_tag="HMPREF2764_RS03345"
                     /old_locus_tag="HMPREF2764_03350"
     CDS             18981..20168
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520162.1"
                     /locus_tag="HMPREF2764_RS03345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2764_03350"
                     /product="site-specific integrase"
                     /protein_id="WP_070496593.1"
                     /transl_table=11
                     /translation="MVISKTKKYKGVYKDSKGKIYFQIELGVDPITGKRIQKKGRKNQQ
                     GLPFNSFKEAYEEILRLKHEFVNSTINNSFLTFREFMEEIYLKYYQQKVQFVTYQTALP
                     HHQLFIKQFGSKKLSDISTIDCERFRLAIIDKYSSNYAKNMWSRFKACLGYAERLGYID
                     RVPFKGLDNPRGKHPDTKFWTFDEFKKVINSFDISEYEGLHNYMTIWLYFMTGLRVSEG
                     IALKWEDIDFERKWIHVHSTIEKDKNGVWYAKQQTKTVAGNRKIDLDDFTITILKKWRE
                     VQIKNDDKDYVISRFGAPLCKSTISRIIKRHAKITGVPEITGKGLRHSHASYLINVLHK
                     DTLYVSYRLGHADKSTTLNTYSHWYYSGDSTISEEITNSLDNLGLSIYLPNSCQS"
     gene            20635..21537
                     /locus_tag="HMPREF2764_RS03350"
                     /old_locus_tag="HMPREF2764_03355"
                     /pseudo=""
     CDS             20635..21537
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002932028.1"
                     /locus_tag="HMPREF2764_RS03350"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2764_03355"
                     /product="DUF2268 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MQINMIRSDKVYQEMLELPLEKREGCF"
     gene            21600..21968
                     /locus_tag="HMPREF2764_RS03355"
                     /old_locus_tag="HMPREF2764_03360"
     CDS             21600..21968
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013639.1"
                     /locus_tag="HMPREF2764_RS03355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF2764_03360"
                     /product="EXLDI protein"
                     /protein_id="WP_070527136.1"
                     /transl_table=11
                     /translation="MHYKKVELKVTNQGIHERKIFQGVKIFSRSKLSKDQKNILTQKLY
                     LTPKQNIVYYQRTDINYDQNWYHHKDYYELAYGQMDRETVFKVCQDFDELSPFLENELL
                     EKLKEKQSTGKFFEKLDI"
ORIGIN
        1 aatatagtta ttcaagttga aaatcttaca ttattagctt ttaaaaagct aaagaatata
       61 gctataattc ctaatacaat aaattatttt gtagctatag attcaaatga tggaatttac
      121 tttggagaat tatttcagtc aaagatacaa aatggagtga attctcatga aatggtagca
      181 aagggatttc aagaaaatgt ttatccagaa ttaaatattg atattttagg ttttatacca
      241 atcggtgata aatttttcaa gttacctggg actcatactg taggattaac tgataaagtc
      301 tacatagcag atagaaatat aattgaacat ttcgtatcct cgatagaagt taaaccaaat
      361 tcggagaaaa aattgtcatc cttttcaaat ctatcgttaa attctcaaaa ttaccctatt
      421 tcttttcagc ctagaacttt atttgacaga catttattaa ccattggcac aactaatagt
      481 ggaaaatcaa catctgcatt gtcgatatta gataaattaa taagtaataa tatacgtact
      541 ttgattattg atcctaccgg tgaatatagc ttatcttttt cagaagatga agttgataaa
      601 tacgttttag gagaaaaagc gtttgttcct gtatccgaat tgtcaatgca gtaatggtca
      661 atattatttg aaaccaatga tggtactcaa cctgctgttt tagcagaagc aattagaggc
      721 ttaagatatc aattgaagca gggattaaca ggaccatatg taaaaattgg taagtcagta
      781 aacgttgtag aaagagaatt aaatcagcta acatctaatg ataaagattt cgatttatca
      841 cttttaagtg agcagatagc taatgaaact actcaacaaa caaattctgg tgtgtataag
      901 gcagatgcat ttaattttgg tataaatcaa tatctgatac aaaaggtaaa ttataaatta
      961 gctaatacaa attttaaaac attctttagt tctcaaaaag agaacttatt agatattata
     1021 aaaaactttg caaccacatc aaaaaaatct ctttatatag atgcatcaag gattggtact
     1081 acagatggta ttggtgggat gataattgat ttggtaacaa attttttatt aaacatcccc
     1141 aaaaatgaga tcaattcatt cgtaattttt attgatgagg tacaccgata tacaaaatct
     1201 aataacatag gagagacatc attttatacg gggctaacag gaattgcaag agaaggtcgt
     1261 aaaaaaggta tatttctttt tttaacgaca cagaatccta atgatgttga taaaattcta
     1321 ttaggtcaaa ttggtacgtt acttattcac cgtttaacag ctattgatga gattagagca
     1381 attagtaatc atttatctga gcagcagatt gcacaagtca ggaaattgaa tactggtgaa
     1441 gcagtattaa ctagtataaa tttactcaaa gatttatatc ttgagattga aaaatgtgat
     1501 agagtacata tgaatgatac tccaagtcta tggcaagatt gaaaatctag ttggagagtt
     1561 atatcttttg attttgttac atcttcattt ctgagagctc aggctctctt tttttcccct
     1621 catttttcat gttgtgatac cttttccaaa tcatccttgt tatcctaata ctattcctaa
     1681 gaaaatcaat ttttgatttt ctatgggggt ttgggggcga agtcaccaag ttatcttatc
     1741 gttggctgtc aaaactagaa ggttttgata ggctggcgat atgatttttg ggatattgtg
     1801 gacacaatat ctgagctcgc aaaagccgaa aaagaacctt tcgaggcttt taggaagcac
     1861 ccgtatccca tacggtatcg gggatgaccc gatagaggca agtagagaag gagtatgaca
     1921 agatgacaga ccaataccgc attatccgta aggaaatcaa tctgacacca gaggagctgg
     1981 aacagattca gaagctgatg aaacaggaac atgtagagca attttctccc tttgttcgtc
     2041 aaaagctact tgatgcaatc gagggaagaa agtcaatgac ggattggttt accctctggc
     2101 aataccaaaa gatggaacaa atcagccgag atattttaca ggtgactatc ttggctgaac
     2161 aaagccacca agtcacggca gagcacctac ggattatctt gacctgcgta caggagctaa
     2221 tagcagaggt taaccagact atcccactca gtcaagactt tcgggacaag tacatgggag
     2281 gttagggatg gaaaatcgtt accgaactaa tcttaaaaaa gtttttctga cagaccagga
     2341 acttgcgacc ttgtacgacc gtatcggaca gagtcgctgt aaaaatttct ctgcttatgc
     2401 tagaaaagtt ttgcttaacc ctaacatgac cttcctaacc attgacacca gcaactatga
     2461 agatctggtc tttgaactga aacgtatcgg aaacaacctt aatcaaattg cacggacggt
     2521 caatcagact cacatcttaa aaccatgtga ccgtgagttg ttggtacagg gcattggtca
     2581 attgattaaa gaagttgaaa gtgactttaa tattaaatgc cagcaactga aggagtttta
     2641 tggtagtcac taagcacttt gcggttcaca gcactaagta tcgcaagagc ctcatcaagt
     2701 atattctcaa tcctgaaaag acggagcagt tgaagttggt ttctgatttt ggcatgagga
     2761 actatttggt ttttcctagt tatgaggaga tggtggatat gtatgaggcc aacttaacta
     2821 acaatgacag gctctacgat tccagaaacg accgccaaca ggtcaaacaa actaaaatcc
     2881 atgcccatca cttgatccag tctttctcgc ctgatgataa gctgacacca gaggaaatca
     2941 accgcattgg ctacgagacc atcaaggaac tgacaggtgg aaactttcgt tttatcgtga
     3001 caacacacac agatagaaac catgtgcata atcatatcct aataaactct gttgacctca
     3061 attctgacaa gaagctcaaa tgggattacg ctcaagagag aaaccttcgc atgatttctg
     3121 accgcttggc caaggaagca ggagcaacga ttatccagcc taaccgttat tcgcacgaga
     3181 agtttgaggc ttaccgcaag accaatcata agtttgaact caagcaacgg ctttattttc
     3241 tcatgaaaca cagcaaaaac tttgaggact ttttggccaa ggctcctgct ctaaacgtgg
     3301 agatggattt ttcccacaag cacgccagat tcctcatgac tgaccgagag atgaaacagg
     3361 tcattcgcgg taagcagctg gataagagac agccctacac cgaggactat ttccgagagc
     3421 agtttgcgac acgagccatt gagcagcgat tggattttct tttgcctaga gcccgtgacc
     3481 tctctcatct tttggaaatg gcagagcagt taaacctgac aatctccctg aagaaaaagc
     3541 atgtgacctt taccttgact gagaacggtc gaaccatttc tatagagaat aaaaaggtca
     3601 gtacgaaaaa tttgtacgat gtccagtttt ttgaggatta ttttgaccaa agagaaagca
     3661 taacagagtc tgacttgact aactttgtct atgatttgaa gacctatcaa gaagatcagg
     3721 acaaggataa actctcaagt gaggaactcc taacagccta caaggagttc aaagagaaac
     3781 atgaccagat tcaggagttt gaagttgtcc tagcagagta tcagattgat aaggtggtca
     3841 aggaaggtct tttcatcacg atgaattacg gtgtcaaaaa agacggcttg gtctttatcc
     3901 caaaccgaaa cttggatatt catgagaacg aacaagacaa gtcctaccat gtctttatac
     3961 gagagaccgc ccagtttttc atctttaaca aagaaagttc agacctcaat cgttacatga
     4021 gagggcgtga actaatccgt caacttactc acgacagcac gcatatccct aaacgtaggc
     4081 ggccaaccat tgccaacctc aaagagaaaa tcgcagaggt gaatcttctt atcgaattag
     4141 accttaacaa tcagtcttac caggaaatca aagatgagtt aatcaaggaa atcgcccagc
     4201 tggatttgac cattacagat ttgcaggata aggttgctca tctaaataag gtagcagagg
     4261 tcttaatcaa tctcaacaac tcagacccag aaaatagaag actggcaaaa tatgactatg
     4321 ccaagatgaa cctgacttca gctatcaaac tggagcaggt ggagaaagaa atcgaagaaa
     4381 atcaaagatt tatgactaaa tggatagatg attatgaata taagattagg agattagaga
     4441 attttatcaa tatacttgat aacacaagaa atcaaaatgt taccaaatta gaacgggaaa
     4501 caaaatcagt atagttattt gagataccat ggaaaaatta taaggctgat agtattaatt
     4561 tcactatcag ccttacaggt tatttaacgt ttcagaaaaa actataatgt caagattaac
     4621 taaacagtat ctaattcttt caaataattt tctatcttca tcaacattaa aggattgtta
     4681 taaatcttac ataactcttt tgcttctata taataatttt tgacttgttc tttgtctaga
     4741 aatttggctc cagcatttcc tacaagaata agtagaggag ccagttggta gcttgtctgt
     4801 ctttgtttac agagttcaat cgtctcaaga gcttcttgga tagcttcgtt atatttttcc
     4861 tttgacacta ggtagtgagc gtagttgtaa cgaactctga tgtagccaaa taaatactct
     4921 tgatgctcaa aatcttttgt ctgatataac tccattaaat gagagtagtt tgcctcatat
     4981 tcttgttcac gacccactaa ggaatagaaa ttagatagag tattcaatgc ctttaaataa
     5041 atcagagtat ttgaggagac ttttaataat atattttcca atgaagaaat agcctcacac
     5101 ttactgtcat attgatagaa gtcaataata gctttaatcc attcaaggta agttcggtct
     5161 tctagtgtta gaaaagtact tcgttcaatc tctattctat aaatatattc caaattgtca
     5221 taatttctgt catctaataa tcgagcagat aattgcttga aattagagag gttagattta
     5281 atttcaattt gttcattaaa aaaataatct aatggtactt caagtcgttg tgagagtttg
     5341 aacaaaagat ctgcggaggg aatgaaatgc cctctctcaa ttttactaat ctggctttgt
     5401 tcacaaattc cttctgcaag agtttgttgg gagagtctca actcttttct tttcaatctg
     5461 aatttctctg cgagtgtatt cattaaagat aataaacctt cctatttgtg tgcttaattt
     5521 cattataaaa tttttagttc aaaatagcaa gttaaaggaa tgaataattc tttatggcaa
     5581 taaaataaaa aaaagttcaa aatgtaataa aaataattga ctaagtaata tatatatgtt
     5641 agaataaaaa caaggaaaca gaaaggggtt tcattgcatg agaaaaaaat gtgggattaa
     5701 aaaattagtt acatttgcat tactaggtgt ttttatgttt agtaatacaa ttccttacca
     5761 acagtttatt cagaagaata aacaattgga gattcgagtg caatcacaaa agaagtccaa
     5821 tggtcttgat gttgggaagg ctgattagtt gattaaatga tgaaaatact attaactata
     5881 tagtatttct gttttatcta atttttaatt agaaagaagg gattccaatg taccagggtg
     5941 tgatttgttg atacttctaa atgcagtcat tgttatagtt agattttaag tgaaagaaat
     6001 gagggcttta cgatgaagaa aagcattaaa aaaataatta caacatcttt acttgcactg
     6061 actttagctg gtgcaggtgg ttcgattgtt tcagctgcaa cagtttggta taaaggtact
     6121 gcagtttatt ggaattatgg tcgcactgct ggtctttgga gctattcaaa tgttcagtct
     6181 ggtgtttacg aacactcagc atctgctaac ggggcattct caggctggcg atcccctgga
     6241 gtagaagcac gtgcttctag attcatcgga actggtacag ctgaatgtta ctggaattgt
     6301 aggtaagtgc ctatgacata caaaaacatg ttattaggta aaatgaaata cttaatcctg
     6361 tttttgattg ccatccagag tatcttactt gctctggtgg caattttttt agcaggttta
     6421 cagtatcaac agtcatggca gagttataat catcattccg ggaccgtaac agtttatctt
     6481 cagaagttaa cagaagagca atcacaagat gtatttaatt attttttaga acagagtgac
     6541 ttgtccatat ggacaaaacg ttctgaaagt agtgatacag gagaaggtcc aaataggatt
     6601 tatatagaca tccttggtag ctctgctggt ttttcagatt ttgaaagtac gggtaaaata
     6661 gttgtctcac aacaacaatt tgcaaattta ttatctcata gtgataatag tatgactatt
     6721 ggacttgaca aaggctcaaa taatatgctt tacgagcttc cagatttatt atttagcaca
     6781 cctgtagtca ttgaacgatt agattatact ttccaaaaca ctaatacgat taatgggata
     6841 taccatatca atggtctcca cgatgctgtc tcaagagata actttttgct gcatctttca
     6901 aaggtgtcag gtatttctgt tgaggatttg acaaaagaaa gttttggaag tagtactgat
     6961 cagggaattt ggggaataat acttgctatc agcatcttag taaatgcctt cattttactg
     7021 atcctattct taatctgtgt tcttcaatcc tttaaacatt tcggaacatt gattctttta
     7081 ggatgggata gaaaagaatt atggtctgct tttttcaaaa attctctact attttcaatc
     7141 tacactattc caattatctc tttatgtagt tggttgttgt caggctggtc tagttttggt
     7201 ttatcatcgt ttattctagt ttttgctgga gtcagcctct cagtcttgtt gctactattt
     7261 atattcatta ttccaacgat tattgtttat tcggtttctc cattagccgc aattcataaa
     7321 cgattaccaa tgaagccttt aatggtaacc tgcttgttat tctatacctt ggtagctggt
     7381 ttgttaatcg cagtcagtta ctctttagat gctccaatga atcagtttat tgataatatg
     7441 aaagtatcta gggagtggaa gaatgttgaa gatatgtacg ttatatccag atttgttgag
     7501 ggagatgatg taggtacata tgcaggaact acaaattccc ttgagcgtag tatgtataac
     7561 ttttaccagc gtatatctga gcttccaggt gtctatattg cccaaggaca atttcttaat
     7621 caggagtccc ttgatgcagt ctatgggaca taccagcatg tccctaaaaa accattttgg
     7681 tatttgaaat tctcctataa ttacctgcaa gacctaggta ttcccctaag tgatgaagag
     7741 ttgctagaga tgaggaatgg tactcgactt tatcttctac ctaacacgct caatacagaa
     7801 gaacttgagg tgatgaaggc gtatttacag gaaagtgtca ctgtaaaacc gggagattta
     7861 caaactaatt tcacagaaaa tcagaaattt atgttcaagg tttatcaacc gtctcgacca
     7921 atatttactt ggtcagattc catttcttat ggtacaacta gtgagaatcc agttattttt
     7981 gtctcaacac cagagaattt atatttcatg gagtcggcaa acttagttgt cagtggctat
     8041 aatggtcttt tgaagattcg tgatagggaa acgatggaac aggtagtgtc cgttttagaa
     8101 acagaatttc cagatttaac ggataatcgg ttgagtttta caactgtcaa gaactttatc
     8161 aatggtcttc aaaaagatct gagttataca ttttatcttt tcggcacgat catagcgatt
     8221 atcataatta cgatgatggc tattttctgg agttttgtct taatgtaccg cttgttattt
     8281 gaagaaaaat tgtatgttca atactttatg ggattctcac catggaaaag atatattggt
     8341 gtgctttctc tcattattag tttttctgtg gtggaattaa tcgtttctat cttagtgggt
     8401 tctaagttgg gaatagtcat gacactagct acatttgctt ttcagataat gcttctttac
     8461 ttcagcttgt tccgtaaaga aggagagagt atcatacaat tatttaagga gtaatctcat
     8521 gtctagaatt tcagtacaaa atgtatcaaa acaatttggt tcaagagaaa ttttcaaaga
     8581 cttaagcttc gatattgagg aaaatgaatt tgtagcttta gtaggacctt ctggttctgg
     8641 aaaatcgact atcctgaata tgattggact attggatact gttgacagtg gtaaaatcct
     8701 aatcaacgga aaagttttgc ctaaggtaaa ttcgcaatca gcagttcatt accgaaggaa
     8761 tgtcatcaac tatctttttc aatccaatgc actcatttct acatctagtg tgaaagataa
     8821 cctgatgctt gccatgactt tttcgaattt ctctagacag gagaaggagc agagaatcaa
     8881 ggaaacgcta gaatttgttg gtctacaaaa tcggttaaat agtaaaatca atgaattatc
     8941 aggaggtgaa cagcagagaa ttgcgattgt gagagctatt ttaaagcccg gagatattgt
     9001 cctagcagat gaaccaaccg gatcgttaga tcctgaaatg tctcaaaaag cattcgattt
     9061 gattcgaact ttgagagatc aatttggtaa aacaattttg gttgttacgc ataacatgga
     9121 gcaagcacgg caatgtgata ggatcatttc actggagtcg gttcttgtaa attaactcaa
     9181 ccattattag cacttgatac ggttgcttta gattatggaa tatcgaaggt ggagagttca
     9241 aacatgaaaa aatttacata cgatattata aaacagccaa gtgtgtctaa tcgtttggag
     9301 ttaaaaacac atgtactggt tgaaaatcat attgatgatg tcatttgtct gtatatcatt
     9361 gctagtaata aattattaga tatggttatt ttgaacccat ttcaaaagaa aactatattt
     9421 attccatgtt attttgagga agatattgtg aaagtcaaag atgattatga aattgagtgg
     9481 gatttgttag aatttcaaaa atttagagca tttttggctt agtaatatgt gttgaaggat
     9541 caaaatctat ggtaaaaagt agctttgaaa acgtattacc tccaaagatt tagttaaata
     9601 atgatttaac acaaaaagat attattgaag ttctggaaag atgttgtttc agtatagaaa
     9661 taagtcttga aaaactggat ttgaagaatt attttgatta tattgtttcg gattatttct
     9721 cagcgttcag attggtaact tgcagatatt tatcatataa aggtatatca ggtccactag
     9781 taggaaatag gcaagattct tatcgattaa taaataataa ctgttatatt ttaataattg
     9841 ttgtcaccta aagcatattt ttcagagcat cttaaacgat tttattgtat tctaacaata
     9901 gaaatactat tttagtttta ctaaaatcta gaatatttga aaactaattg gcttacttat
     9961 atatgaaatc atccctaatc tgcaacaagg agagtaacca atgaaaaatt taggacaaat
    10021 cttaaaaaaa attcgagaag ctaagggcct ctctctttac aatgttgcta atgatgagat
    10081 ttctacctct cagttatctc gatttgaaaa tggatataca gatattactc ttagtaaatt
    10141 actttcagtt ttaaagacac tggatgtatc tttagaagag tttatgtatt tagggcgtgg
    10201 ttttcataag atgagtaatt tcgaggtaat tgataagata aataattatt tttataagaa
    10261 caacagccca gccttgagaa gactcctcat taattgtaca gaaaaggaaa aggagaaact
    10321 aagtaagaaa ttaacaataa ttttgattaa gttaaagctc caagaaattg agaaagataa
    10381 tattgtgact tctgaagaaa ttgattttat atcagactat ttattcagca tagatatctg
    10441 gggtgaatat gaattagagc tattttcctc cacaatggaa attttttgcc aatcaagtat
    10501 tatgatatta acgaaggaaa tggtgaggag aactgatttt tataaatatt taccgaccca
    10561 tagaagatta attactagta tgttatttaa tgcttttagc ctcagcgtag aaagaaataa
    10621 tatagttgat gcatcttatt atagagaaca attagtccag ttattttttg atgaaacaga
    10681 attatatgaa agattagttt ttcacctcat agatagttgt tacaatttta agatgacaaa
    10741 tgaattgagt aatattttag agatgagaaa gtgtattggc tttctgaaaa ccttggaaag
    10801 catgaattta gtagatagat gggaaaaata tattgagaga gtacttaata gtaactaatt
    10861 gcaaattagg gataaaaact attagaccaa ctgctagtga tataataaaa ttaggcagta
    10921 ggtctaatag tttttataat caaggaggat taatcatgat taagaacaat aagattgaca
    10981 acccgtctgt aaaaattgaa aaagcaactg ttgtaaataa caaaggatgt agtgtttgcg
    11041 cgattggtgc tgtttgttta gctgacggtc caattcctga ctttgaaatt gcaggagtat
    11101 ctgctgtatt tactgcattt ggataattgc taattataaa ttaaatatct aatatataat
    11161 gacctactgc ttattttttg attgaaagag gataaaaatg tatttagtgt tggataatca
    11221 agttacaata tatcaaacaa aaggggacta taatgtaatc gtcgagaaaa tcgatgcgaa
    11281 caaacggaaa caatttgact attttacagt taataaaaca ggaaaattac ttctagaagc
    11341 tatcaacggc aagcaaaata tggaggaatt tatagaaaac tttattgata cttacaactt
    11401 agtagaagat gatcgaagtt ggattgagac atttttgaat gaaatgatga aaaaaggagc
    11461 cattgcaatc aaagagagcc cagagattgc aaatttgcct ctatatattt atggaaattc
    11521 aagacttatt tctcctttac atgtaacagt tgagattact gaaaaatgta atttatattg
    11581 tgctcattgc tatttaaatg catcctgtaa caaaacaact gcaattgatt acgagggttt
    11641 caagtctctt gtgaaaaaac taaaagcgag taacgttttg agtattgaaa tcactggtgg
    11701 agaagtattt atgaataagg atgcagaaaa aatactagaa ttggcattta atgagtttag
    11761 tagagtagcc ttattaacaa acggaacaat actcaagaaa agtagcttgt cgttattaga
    11821 gaaaaacaaa gataaattag ttatgagtat ttctttagac agtgttagag aggaattaca
    11881 tgataagttt agaggtatgc gaggctcatt taggagtact tgtaaaaata ttaggcgtct
    11941 gacagaagcc ggaatacatg tacgagtagc ttcttctatt tttgatgaaa atatgtggga
    12001 ggttgataaa cttgctgagc ttgcaattga gttaggagcg gaactttttg tttataattt
    12061 tgtagaaaat tttggcagag gtacggactt caataaaaat agtagtacga aattttcaaa
    12121 agagtactca cgttatttga gtgagacggt atttaagtat agagcattaa ttccaattat
    12181 cgaatcggag gattatctaa aatcttcttc taattgtggt gctggaacaa atactatttt
    12241 aattggtgca gatggtaatt taagaccttg tcctatcttt cctaagaata agattttcaa
    12301 aaatataaac gatggtagta tggaggaaat tttttctgat gatgtttatc aaaaaattag
    12361 caatatctat ccccctagtg atgaaaacgg ttgttctaaa tcttgtccaa attacagtaa
    12421 ttgttttgga tgctacatga aaggactgga aagtaatgta gataaagcac cagaacaata
    12481 ttgttcttgg ataacttata ataaattaga gaagtttatg gaacaatata agggagggaa
    12541 ggttattgag taattatctt ttttcttata aatattatag acctattcct aatttattta
    12601 ttaaacaaaa actaagagaa attcataagt tacttaagga tgatttaata aaatttggaa
    12661 tcgaaaacgg aataataatt tcaatttttg ctctcggttg taatgggaga atgacagaaa
    12721 ttatttatat aaaatcaatg tatcgtattt ctgaagataa aatttatgat atgttaaatt
    12781 ttttatataa taaagaaatt gaactttaca aggtggtaaa agatgataac attaattgta
    12841 caatatcttg ctgcggagta actgcaaatg cttctattcc tacaaaagaa tccttaggat
    12901 actttttaaa aaatttttta aaatgggaaa attatagtgt caaaaaatat tctagagtta
    12961 aattagaaac tacagaaaat attataatta aagaaggaga attaacgtat gtcggtttcc
    13021 tatgtgataa tatagagata aaagaattag gagatatgct gtcagctaag ttattagaag
    13081 aaatttttaa atcacaaaat agcgttttaa cagagattag aaatcaagga ctttgttaca
    13141 caactgtatc aaagtttcat gaagatttga acgttgttta tatcggacta ataacaagtt
    13201 attcaaaaga taaaatttct agattagata ccatgtatac caatgttcag ttaactgagg
    13261 gcgagttcga acttgctaaa tgtcgattga aaaaagaaat aatattttca acaactttat
    13321 atcaaataga ccattactta ttaccttttc agctattaaa aattgatgca aatgtatcaa
    13381 ctttgttaga aataatcgat aaaataaaat tcgaagatat tgtgaaaatt tttaatagca
    13441 ggagaatagt gtgtttaaaa gcataataag gaggaagtta atggagaaag attgtacgtt
    13501 ttttattaaa ccagtttcag atttaggaga agttactatt gagagaataa tttttaattt
    13561 taatggttca attagggaag ggtatttaca ccttttagaa catctatggg ttagagctaa
    13621 taagtcgtgg tttgatgatt atgaaagtaa aatgaatatt tttaacgctt taacgaataa
    13681 gaatcgaatt acatttattt tggtatatac agaatcaaca gttaatacca ataagttaat
    13741 atttgattta aattttaatg aacaggactt cttgatcgaa aaaaagacta tttacgaaga
    13801 aagaaaatta tattcggata gtacaccaga cgttgatatt gttttaggaa gtcttagaac
    13861 tattgaagcc tttgatttaa cagttttaaa aaatatgatg catcagatga attataaaaa
    13921 aattcgtttt catttttcct caaaaaacaa cggcaaatat atgaaaaatc ccactattaa
    13981 tataaacaaa tattcgataa tttggaagga ttctaatact attcaactca tagattttta
    14041 tgattataaa gtgttgttaa ccattttaaa agtgtttaaa ataacgaatg acaatttttg
    14101 ttttaatgtc aacgaggcaa aaggaaatta tgagatcaca tttgatgatt acgaagtctt
    14161 tgattttatg ctaaaaaata aagataatgt cttaatgcga taccagctac tacttactaa
    14221 tactcaatta tttatagaac agacaactta tttatttgat ctttttggtt ttaattttga
    14281 tatattagac ttttggagag aatttaattg ggaggtttta gaaaaatgaa aaaaaagcaa
    14341 taattctatt tctaatcaac ctagttctat tggcattaag aaatatagtt aatagttact
    14401 gcaatttaga atttaaaata acaatcggag attttatagt gttaggaggg ttattaattc
    14461 tatgtgaaca gaaatatata aaggtactac tatctatctt atctacaaga tctgctttaa
    14521 ctaactataa acaaattgag tatctaattt atctgataaa tgctaatatt ctgatgtaca
    14581 cattgataat gtattttaac actttttctt tttcgtcatc aatcatcaat ttatattata
    14641 aaaattactt cttaaatttt ttaatactta tattttcttt ttcttatcta attataaaat
    14701 ataagttact ggttattaaa tataaatatg ttttaattat attgactttc attcttatgg
    14761 gtgttagtgt attagacttg ataacatttg tttttttggc aattatttca tttatctcta
    14821 gtagattaac aaagttcaat actaattatt tctcagcaat aatatttcca atggtattag
    14881 tttattatat tgtgtttgac aaaaatatat tttctatagt ttgcacatgt ttattacttt
    14941 ttagctacct tgtaccaata atcttagaaa ggaaattaaa caatgaacaa aaaacttaga
    15001 atcgcaattg ctatttgctt ttttgtaggt gcatttatgt ttgttttcat gaaagaatat
    15061 ctatatgcag ttgcttttat gatagtgggt ggagtatatc tgtataaagg agtgagataa
    15121 tttgacaact ctattagaac taaaaaagtt gaattttgca tattttaaga atagtaaaat
    15181 attagataac atagatttaa ttttaaatca aaacaaaatc tatggtttga ttggaaagaa
    15241 cggtgctggg aaaacaacgt ttattaaaac tttaagtagt gtatttaaca ataatgtttt
    15301 tactctggaa tattttaagt ttttcgataa agaagtccag ctgagttcag aattttatcg
    15361 acaaaataag tttacagtat ttacagaaag tgaaagcttt ttaaactgga cttttttgca
    15421 atatttggaa atggtctgtc aactttataa ttgttcgata gaaagaaaaa gattggaatt
    15481 tttagttaac ggatttaaat ttgaagagta ttgcaaaaaa gagatcagag acctttcaac
    15541 tggtaataaa aagaaagttt tcttgatagt aggattatat cttagaagac ctttattgat
    15601 tttagatgaa ccgtttgacg gtttagattt cgagtccacg gaatttttat ataagatgtt
    15661 actggagtat aagcaatatg gtaccgttct gttaagtact cattttgcag agagtgtcgt
    15721 acgagtttgt gattatcttt atattctaga aaatgctcat ataaacttat tccaaggaaa
    15781 tgtgtctgaa tggttagagt ccatcaggaa ataaggagga aatctgtaat gttatggata
    15841 tccatatgta gagatttgtt ttcacggaaa agattttatt ttttgggatt ctctttaata
    15901 ctagtcttac tcatacgaca tttaatacct tctcataaca atgtgaacta tcttctattt
    15961 tcagcaacac taattacctt agtaagtact tggcaactac ttttatctta tttcaaatca
    16021 gaaagaatcc aggcatatta tcaacttcct atttctaaca caaagtttta tatccaattt
    16081 atatttgtgg cgtttgcatc taatctaatc gaaagattgt cattgttaat cattcttttt
    16141 agtgaagcaa aattaataaa tttgatacta cctatattgt cttccctctt tgttattatg
    16201 agtagcttta gattagttag gtgttttgga gctttaaata ataaagtgac taatctttta
    16261 tcattacttt atttttttat ttcactgtca ttgtttctct tattgaaatc aatttatttg
    16321 cttttgttca tgattgctat tgagttgatt tttattttaa gagatgataa ttttttgtat
    16381 ttagatgatt tttcaaatac aaatcatttt ttaaagttta aaaattattt tgtttcaaat
    16441 ttggtaaaag agagatattt ttattttaat actgtcgcct cagtattatt tattttaata
    16501 ttatattttc aaaaactacc tgaaaactta aaaatcccat tactattcac tgtagcatct
    16561 actaatacac ctcttactag tttaatttct agcgagccac aattaagaat acatttgcga
    16621 tcactaccta aatcttatat tttttacaat atgtatctaa ggtgtttatt atactattat
    16681 ctttttataa attttctaat tgcaattgtc tatattacta gttcacacag tataatattt
    16741 ttagtatggg tagggatatt tactttattt gagagtgcgt tatacctatt tttagaaaag
    16801 tattggtata ttaagaaatg gaacataaag aaggaactat ggaaacatcc tcgcaaatat
    16861 attgttccta tgatgactta tctatttttc tttattctac taatgttaaa gaaattctaa
    16921 agcccatttg tagaataaag tgtaacatag tatttaatcc tttcaagctg tttgagtcaa
    16981 ctcaagcagc tttttcgagc acttatatcc atgaattatt ctaggctttc gttaaatatt
    17041 tttgtactat ccgctataaa atcttatttc aattctttga gtgaatttgc ttttgaaacg
    17101 aagtcacgta aaggagtgat gaagttctca tcgaatgtat gaccatagga tgaataggca
    17161 cgggcaaatt aaatttttaa tacctcttat ttaattgagt aaagaaaact cgatttcatt
    17221 atcagtagta atgatttgat tacaagcagt ttcttgcgtt atgacacatc ttgattgaca
    17281 tattctacct tcttatctaa gagtttcctt gagatagcat agcaagtttg tcactatact
    17341 gagatcagaa tagaaggttc actgaccata ttttaagcaa taacagaatc catttcacaa
    17401 tatcagaaac gtatccaatt attaatttct tctactccat cataaatttt tatcacctag
    17461 ttgtttttag gagatatagt cttggtagat ttattaaaaa gttgtacaac actgggtcat
    17521 tcaataaact tttcttgatg catatagtca taaagcatct tggttaaaga aaccaatgaa
    17581 tcaaaatgat ggaatttata agtgtggaag aaagttttca tactatgtcc ctttgttttt
    17641 tctttcatca cttctgtgaa ctctatcaga aagtcaggct aaatcttatt tagttacaag
    17701 taatagctag cttctataga atgataatga aaattctaga ttggatttgc ataatactgt
    17761 tatcagtaga tcttctatca ttgatttgtt tcaccggtat tacagaatct cgattagttt
    17821 tacaagtaaa aatagaacgt tttctatcct aacgacgagc agtataagca gttttttcct
    17881 ttgtttaaat aaaactaaaa tttagtattg ttcagcttca gagaagtgct ggtatgattg
    17941 atttgtgaac attttcctat aattttgtaa tatttttgag actataatat attagataaa
    18001 catgtctttt gtgtttcact ttattttaca ataagactaa tttttgaaag tcagtaattt
    18061 taaatagttg ataaaatctt tgctctcagt cggttaatag atatgcttat gagaagtgtt
    18121 taataaatta attttagttc aaaatgtcca atttggacac tttgaatgat ttcttagttt
    18181 tatatattat acttttctca ggagaaagct agatgtacag acgtttgaga gatttgaggg
    18241 aagatcacga cttgacccaa aaacaaatag ctgaaatact ttcgtttaca aactcagctt
    18301 atgctaaaat tgaacggggt gagcatacgt taacagcaga tgtattggta actctctcaa
    18361 acttttacga tgtcagtaca gactacctat tgggattgac agattttcct gataagattc
    18421 gctttagaaa ataatctcct caatttcata gagtgtgaaa atgaggagat tttttatttg
    18481 ttctttgaca attgaatagt ccaaaatggt actttcctca tttgtggagc agatttgaat
    18541 ggctcgccat gataagagcg attttaaaac catcaataaa atagagcgat actttatatg
    18601 ccatgataca aatgatatac aatgatactt ctgaccgttc aggctgccac cgtaaaagag
    18661 cagcaagtgt aattcttatg atgacttcat cagtcatgcc atggaggtga aaaaatctaa
    18721 gaaaggaagt agtaaaatca tggaaacagt aaactataaa gatttagttg cgattggttt
    18781 tccagagcac acatcgagaa atattattag acaagcaaaa aagattgctg taaaaaagtt
    18841 tgaagaagct agaaaaaatg ataagaatgc ggtacaatta ggatgttcac ctttcgataa
    18901 taaaaggtta ggcattgctc ctaaaaatat tgtagaaaat ttaattggta tttctttttc
    18961 agatatagaa ggtgagaaaa atggttatat caaagacaaa gaaatataaa ggtgtataca
    19021 aagattcaaa aggaaaaatt tattttcaaa ttgaattagg agttgatcca ataactggga
    19081 aaagaattca aaagaaagga aggaaaaatc aacagggact accgtttaat tcttttaagg
    19141 aagcatatga agagatactt cgtttaaaac atgaatttgt gaactctact attaataata
    19201 gttttctaac ttttagagag tttatggaag agatttattt aaaatattat caacaaaaag
    19261 ttcaatttgt aacttatcag accgctttac cacatcatca gttatttatt aagcaatttg
    19321 gtagtaaaaa attatcagat attagtacta ttgactgtga aagatttcgc ttagctatta
    19381 tagacaagta ttctagtaac tatgctaaaa atatgtggtc tagatttaaa gcatgtctgg
    19441 gctatgcaga aagattgggt tatattgata gagttccttt taaaggatta gataatccta
    19501 gaggaaagca ccctgataca aaattttgga catttgatga atttaagaag gtaataaact
    19561 cttttgatat tagtgagtat gagggactcc ataattacat gacgatctgg ttatatttta
    19621 tgactggttt aagagttagt gagggtattg ctcttaaatg ggaagatatt gattttgaac
    19681 gtaaatggat tcatgttcat tcgacgattg agaaagataa aaacggtgta tggtatgcta
    19741 aacaacaaac aaagacagta gcagggaatc gtaaaattga tttagatgat tttacgatta
    19801 caatacttaa aaaatggcga gaagttcaaa tcaagaatga tgataaagat tatgtaatat
    19861 cacgttttgg tgcccccttg tgtaagtcta caatttctag gataataaaa aggcatgcta
    19921 agattactgg tgtaccagaa attacaggga aaggattaag acatagtcat gcatcttatc
    19981 ttataaatgt gttacataag gatactttat atgtttcata tcgattagga cacgctgata
    20041 agtcaaccac gttgaataca tatagtcatt ggtattattc aggtgattca acaatttcag
    20101 aagagattac aaacagttta gataatcttg gattatcaat ttacttacca aattcctgcc
    20161 aaagttgaaa attgaggaat taacccacta atactgggag aaaataggat ttgcaaattg
    20221 ttactcttaa ataatagagc aactacatta gtagcttaaa aaacatataa aaccgctatt
    20281 cttaggagta gcggtttttc tttttatctt tcatggggca aactaattat atagtttatc
    20341 taggagaaaa acaagttttg aataatagac tttccataaa aaataataca agtttttacc
    20401 cttcaggatt tatttttttc tggtatcatc attcctatga acagtagaaa agtaagtttt
    20461 taatttattg atactccgga tattacaatc tcagtattaa agaactttat tgaaggtaat
    20521 tttcgaacgg tttgaggtaa tttcaatgaa attttaatag atatttcaat tttcttcttg
    20581 actctgacct taggtaaggg attatactaa tagtagataa gaaaggagat tattatgcaa
    20641 atcaatatga ttcgttcaga taaagtttac caagagatgc tcgagcttcc tttagaaaag
    20701 agagaaggtt gcttttgagc taaaatatta gcaccttttg caatgaaata ccaaacgcaa
    20761 cacattcctc tgaaagcaaa gtatcctgga ggatttgatg ctcttttcct acttggcttt
    20821 atgaatcagt taccctcaac tctctcagaa aaggatagac cagctatcga ctctctgagc
    20881 tctgatcaac tctggcagga ctgccaggat accatcaaaa ggagtattgg gctttttgag
    20941 caggctggct atgacttaga tgttgaggat taccatttta ctattttatt gggcaatcca
    21001 gaaaaaccta tgctacagct caataagggt tacagcggag atggaggaat tccaggctac
    21061 ctcatgctta gtttactacc aaatgactat actttacccc gtgtgcaggc ggcgttagcc
    21121 catgagtgca atcacaatgt ccgctttcaa tttgtcaaat ggaaccagca gacgacacta
    21181 gcagactggg tagtcagtga aggattggca gagtcttttg ctgctgagct ctatggcaaa
    21241 gatttcattg gtccttgggt gacttcaact agtttcgagc agttagaaga gattaagcct
    21301 atcatctcca gtcagcttca gctaacgggg atggcggaaa tggctcctta tctatacggt
    21361 gatgaaatcg cgaagataca gggtcaaatt ccggttggta tgccctatgc tgcaggctat
    21421 gcttatggct atcatctgat acaagcctat ctgaaaagga caggtaagag cattattgag
    21481 gctacagtga cgcctacaga agagatttta gaggcgacga aagacttttg gaaatgacac
    21541 ttttgcttgc aaatctgcca gagtttgata taatgtaggt aatttctgga ggtgactata
    21601 tgcactataa aaaagttgaa ttaaaagtta caaatcaagg tatccatgag cgcaagattt
    21661 ttcaaggtgt caagattttc agtcgcagca aactatccaa agatcagaaa aacattctaa
    21721 cacagaagct ttacctgact ccgaagcaaa acatcgttta ctatcaacgg acagatatca
    21781 actatgacca gaactggtat catcataagg actattatga attagcttat ggtcagatgg
    21841 atagagagac ggtttttaag gtttgtcaag attttgacga actaagtcct tttctggaaa
    21901 atgagctgct ggagaagtta aaagaaaagc agtcaacagg caaatttttt gaaaaattag
    21961 atatataaaa atccggctgc ttttataagc agtcggattt ctttgagtta tagtttgata
    22021 atctttcata agagaaaata gatctatttt tatcatgaac agctaactta gttagaaatt
    22081 gtagaaacag tatagttgaa atctatgaag aataagtgta taatcaagaa aaaatgattg
    22141 agtactcact caattttgta gatgtgtaaa ggagttcata aaatggttgt tcaagcaata
    22201 caatatagtc gtttcggtga tgaagaagtg ctagatttgg tgaacattaa atctgattct
    22261 ttgaaactga atcaagtgag ggtagaagtt catgcagttg gtttaaatcc tattgattat
    22321 aagacttttg aaggtgcaaa gccactccga tttctatctt ttatgacaaa actcaggaag
    22381 ccaagtcgtt ggtttgagtc aaaatcatct ctttttccaa gaggtgttgg tcgggatttt
    22441 gctggagtta tcacagaagt tggtgaagga gtaaatcggt ttgcagtagg ggataaggtt
    22501 tttggaacaa tgatcagtga ccctggattg gggaccaaga ggggagcttt ggc
//
