LOCUS       NZ_CP017599            21914 bp    DNA     circular CON 16-JAN-2024
DEFINITION  Moorena producens PAL-8-15-08-1 chromosome, complete genome.
ACCESSION   NZ_CP017599
VERSION     NZ_CP017599.1
KEYWORDS    RefSeq.
SOURCE      Moorena producens PAL-8-15-08-1
  ORGANISM  Moorena producens PAL-8-15-08-1
            Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
            Oscillatoriales; Oscillatoriaceae; Moorena.
REFERENCE   1  (bases 1 to 9673108)
  AUTHORS   Leao,T., Castelao,G., Korobeynikov,A., Monroe,E.A., Podell,S.,
            Glukhov,E., Allen,E.E., Gerwick,W.H. and Gerwick,L.
  TITLE     Comparative genomics uncovers the prolific and distinctive metabolic
            potential of the cyanobacterial genus Moorea
  JOURNAL   Proc Natl Acad Sci U S A 114 (12), 3198-3203 (2017)
   PUBMED   28265051
REFERENCE   2  (bases 1 to 9673108)
  AUTHORS   Leao,T., Castelao,G., Korobeynikov,A., Monroe,E.A., Podell,S.,
            Glukhov,E., Allen,E., Gerwick,W.H. and Gerwick,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2016) Scripps Institution of Oceanography, UCSD,
            9500 Gilman Dr, La Jolla, CA 92093, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2016
            Assembly Method                   :: SPAdes v. 3.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 98.0x
            Sequencing Technology             :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/16/2024 04:55:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,406
            CDSs (total)                      :: 8,335
            Genes (coding)                    :: 8,097
            CDSs (with protein)               :: 8,097
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 238
            CDSs (without protein)            :: 238
            Pseudo Genes (ambiguous residues) :: 0 of 238
            Pseudo Genes (frameshifted)       :: 87 of 238
            Pseudo Genes (incomplete)         :: 150 of 238
            Pseudo Genes (internal stop)      :: 79 of 238
            Pseudo Genes (multiple problems)  :: 69 of 238
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:37:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6741017
            Orig. end                         :: 6762931
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017599.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Gerwick Lab Culture
            Collection, UCSD, SIO.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21914
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="30"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21914
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21914
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11914](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11914
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(288..301)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.85"
                     /tool="antismash"
     misc_feature    complement(335..350)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.55"
                     /tool="antismash"
     gene            670..2934
                     /locus_tag="BJP34_RS24675"
                     /old_locus_tag="BJP34_24680"
     CDS             670..2934
                     /EC_number="2.7.6.5"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008190525.1"
                     /locus_tag="BJP34_RS24675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BJP34_24680"
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="WP_070394629.1"
                     /transl_table=11
                     /translation="MDAIATYSILNFNVKIPDWLQDSLRAASSAADEPVGDHTLLIAEA
                     FKFAYQLHEGQYRKSGEPYIAHPIAVADLLRDLGGNSTMIAAGFLHDVVEDTEITPEEI
                     ESRFGVEVRNLVEGVTKLSKFNFSSKTERQAENFRRMFLAMAADIRVIVVKLADRLHNM
                     RTLEYLKPEKQVQIAQETRDIFAPLANRLGIGRFKWELEDLAFKYLETNAYREIQSLVS
                     ERRSDREQRLKEVSELLRERIHKTGVHCVDISSRPKHLYGIYQKMQRQNKGFHEIYDIA
                     AMRVIVESKEECYRALAVVHDLFRPIPGRFKDYIGLPKPNRYQSLHTGVIGFNGRPIEV
                     QIRTLEMHHVAEWGIAAHWKYKETGGSHTTKFTADDEKLTWLRQLLEWQKDLKDAQEYM
                     ENIKDNLFDEDVYVFTPDGDVVALSRGATAVDFAYRIHTEVGNHCAGVRVNGEWRVLDC
                     PLKNGDIVEILTTKNAHPSLDWLNFVVTASARNRIRQWFKRSHREENVARGRELLEKEL
                     GKKGFEALLKSAPMQIVAERCNYHKVEDLLAGLGHGAVTLNFVVKRLREELHAGLDNEP
                     EESEVIQEYSSSTSIHLQSQLPSKKHPIAGVEGLLYRLAACCNPLPGESIIGVVTRTKG
                     ISIHRQGCVNVENVLGERLVPVSWNPTDIDNGRPQTYPVNLQIEVIDRVGVFKDILSRL
                     SDQNINVRKAQVKTQYGKPALIDLCIDLLDHQQLKCSFAKIQQMSDVLNIRRVSQVEEC
                     N"
     gene            complement(3149..4105)
                     /locus_tag="BJP34_RS24680"
                     /old_locus_tag="BJP34_24685"
     CDS             complement(3149..4105)
                     /EC_number="3.1.26.11"
                     /GO_function="GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA]"
                     /GO_process="GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011610475.1"
                     /locus_tag="BJP34_RS24680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BJP34_24685"
                     /product="ribonuclease Z"
                     /protein_id="WP_070394630.1"
                     /transl_table=11
                     /translation="MEITFLGTSSGVPTRSRNVSSVALRLPQRAEVWLFDCGEGTQHQL
                     LRSDLKTSQIRRMFITHLHGDHIFGIPGLLASCGLAGNIDRVDIYGPPGLDSYLQACLK
                     YSRTHLAFPFKVHTIKPGLLYEDQEFTVSCLPLEHRVPAFGYRVCEKDRPGRFNVEKAI
                     ALGIPSGPLYGKLKRGETITLPNGRQVQGIDLCGARETGRKVVYCTDTIFCEQAIELAK
                     DGDVLIHEATFAHQDAQMAIERLHSTSTMAAQVALGAGVKQLIMTHFSPRYAPGNPLRL
                     DDLLQEARAIFPNTILAHDFFTYEVPRRRSEEKEVVC"
     gene            complement(4163..4315)
                     /locus_tag="BJP34_RS44400"
     CDS             complement(4163..4315)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BJP34_RS44400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158517452.1"
                     /transl_table=11
                     /translation="MPIPDSLLPIPCCRFPVADSRFPIPDSRFPTPYSLLPTPYSLNTF
                     KGIAH"
     gene            complement(4410..6194)
                     /locus_tag="BJP34_RS24685"
                     /old_locus_tag="BJP34_24690"
     CDS             complement(4410..6194)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0046930 - pore complex [Evidence IEA]"
                     /GO_function="GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0033212 - iron import into cell [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033921.0"
                     /locus_tag="BJP34_RS24685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BJP34_24690"
                     /product="iron uptake porin"
                     /protein_id="WP_070394631.1"
                     /transl_table=11
                     /translation="MLKLTWSLPHVTPAAIAAAFLLTPHGLANESQPKSTTAQELSVAV
                     ELLPPISVGVMEQVTPVSQLFPGSPITELPTSTQEFENELTPNIEPNIEQTDQPMAQVT
                     SVSQLSDVQPTDWAFQALQSIVERYGCMAGYPDGSYRGNRPLNRYEFAAALNACFDQLS
                     KIILAPNLASSYFKEDLEAIKRLQSEFTVELARLRGNLDAVTARTAEVEITEFSTTTKL
                     NGEVDFILIDYFTDNKAAPCCSSPTQDDSLTTTFTGLALLSFDTSFTGKDLLRTRIDTT
                     DVPEFNNPLDGTDMTLYDFETNTDNEFVITELYYRFPISDRIQAHIAAAGLSADEITDP
                     LNPVSALSRFGVHNPLYRLAEGGGAAIRYQFNDSIRISVAYLGSAASISNPTEGNGLFN
                     GQFGAFTQLTLTPNQRLGIGLNYVHYYSPEPNSGIDVTGSTGSQFSQAPFGDQTATSAN
                     GFGLQGRYRLSPGFALGGWLSYINANAESSPRQSGLDGSKGAKADIWTWAITMAFPDLG
                     KEGNELGFVFGMPPRLAENDINSRQDLDVSYHLETFYRYQINDNISITPGLFVIFSPEH
                     NSNNNSIVVPMLKTKFIF"
     gene            6448..7200
                     /locus_tag="BJP34_RS24690"
                     /old_locus_tag="BJP34_24695"
     CDS             6448..7200
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BJP34_RS24690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BJP34_24695"
                     /product="hypothetical protein"
                     /protein_id="WP_070394632.1"
                     /transl_table=11
                     /translation="MNNRLRQFYQFFLNNVVLAIVVGLLTNAIGAWIAELLNNQESFKQ
                     YKAFSMLVFILFTPIASKYLFKILNLALNKIASVSLIILLMVVEASLFSVLPTKTVKLP
                     EQFDNYPDIAQVFEIKNIGKPNSLKKVSIHKAEARGIIRKSLLQPNELHLLLSDVEFIK
                     YEKTFRELIDRNYRGYIQYNINYKPDCIGNFEMESQIVDYSFRPGSGILSFVIGFIETE
                     YLVPRQRTYVINLIEDIIRDNQVLEKIK"
     misc_feature    complement(6479..6492)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.6"
                     /tool="antismash"
     misc_feature    complement(6490..6510)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 24.65"
                     /tool="antismash"
     gene            complement(7245..8018)
                     /locus_tag="BJP34_RS24695"
                     /old_locus_tag="BJP34_24700"
     CDS             complement(7245..8018)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BJP34_RS24695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BJP34_24700"
                     /product="hypothetical protein"
                     /protein_id="WP_070394633.1"
                     /transl_table=11
                     /translation="MLDKTLATIFSTFSISLGLTIALAGDLHAESQFPDGNVPLVAQSL
                     DVFTNQIGFPIELDLTKAQIRGTLPIEKFREDLVNSINQYDGYYIKNTRYNKWKINDIN
                     LQSIDNGGATFSFTVNLRKYECIKIPGVGRKCTRLFSVTPSGDVSLGIAIRNNDLEVAY
                     RNHNVRGRGWYSDALTLLEGVFRNQTVKAVKKGLANFDGVNLISYLKDAGVDKQLKPYG
                     LTLDKLVNAGVSINADVTPKGLNFVIDLPKTITLE"
     gene            complement(8482..9858)
                     /locus_tag="BJP34_RS24700"
                     /old_locus_tag="BJP34_24705"
     CDS             complement(8482..9858)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008190510.1"
                     /locus_tag="BJP34_RS24700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BJP34_24705"
                     /product="glycosyltransferase"
                     /protein_id="WP_070394634.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.2e-17,
                     bitscore: 61.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTIGLAITVLSLGIWIGLLGFRGQFWRADQRLVIEKFPTRSLGQ
                     GESLPKVCAVIPARNEAELLPTTLRSLLAQDYAGCLTVIVVDDQSTDQTATIAQALAQE
                     SNQSSERFQLEVLSGQELPPGWTGKLWALEQGIRHGQQQTPAPDYFLFTDADIDHDPAN
                     LRQLVTKAEMEHLDLVSLMVLLRCQDFWERLLIPAFVFFFQKLYPFAWVNNPTKSTAAA
                     AGGCILISHQALNRIGGIEVVRQALIDDCALAQAVKSSNTTSFAPLAPQRAIPRWGEQN
                     SQSPFRCAPPRASKSPLGRTAKLGDLGGFSKTNQQSPGFGGIWLGLSQSTRSLRPYPSL
                     ASIWNMIARTAFTQLEYSPWLLVGTVMGMILIYLVPPIGLIVSVLTGHWLNAIASLVTW
                     LLMALAYLPTLRLYQCSPLLGFCLPGIGLLYTLMTIDSAWRHWQGRGGGWKGRVYSIEG
                     "
     gene            10001..11914
                     /gene="shc"
                     /locus_tag="BJP34_RS24705"
                     /old_locus_tag="BJP34_24710"
     CDS             10001..11914
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008190508.1"
                     /locus_tag="BJP34_RS24705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BJP34_24710"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_070394635.1"
                     /sec_met_domain="T2TS (E-value: 3.8e-136, bitscore: 453.7,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIQDRIVHSGVTEAIANSQSYLLAQQYPDGYWWAELESNVTITA
                     EIILLHKIWGTDKQRPLHKAEAYLRSQQRKHGGWELFYGDGGHLSCSVEAYMALRLLGV
                     PASDSALVRARDFILRRGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPQWFPFT
                     IYEMSSWARGSTVPLLIVFDQKPVFDSQPRINLDELYTEGADHAKFELPRNSDWTDLFV
                     LLDDGFKLAEDWNLVPFRKQGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYD
                     LADPVVQRGLEAIDRFAIETPDSYRVQACVSPVWDTAWVLRAMVESGLDPDHPALVRGG
                     EWLLQQQILDYGDWVVKNPQGKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLK
                     RAAIARGLAWIASMQCNQGGWAAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEM
                     LGSCNLSIESQQLEKAIAFLIQEQEADGSWFGRWGVNYIYGTSSALSALSKIAPHTHQR
                     SIERGAAWLVQCQNLDGGWGETCLSYDDPSLKGVGISTASQTAWALIGLMAAGEATGNW
                     AMDAIEKGVNYLVSTQQPDGSWDETEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQMSV
                     SS"
     misc_feature    complement(10050..10070)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 24.45"
                     /tool="antismash"
     gene            11951..12076
                     /locus_tag="BJP34_RS49390"
     CDS             11951..12076
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BJP34_RS49390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_267876365.1"
                     /transl_table=11
                     /translation="MQNEELRRQNGEGRRQKAEGRMVKAEGRRQKAEFPILNSQF"
     gene            complement(12164..13045)
                     /locus_tag="BJP34_RS24710"
                     /old_locus_tag="BJP34_24715"
     CDS             complement(12164..13045)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008190504.1"
                     /locus_tag="BJP34_RS24710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BJP34_24715"
                     /product="DUF4351 domain-containing protein"
                     /protein_id="WP_070394636.1"
                     /transl_table=11
                     /translation="MAYDNICKYLAENYPADLVKWLHGIEVTEISVLKTELNTEPIHAD
                     SLTLLQTANQILHWEFQTLPASKPSLPLRMLKYWVRLKEKYNCPIEQVVIFLKFTRSEK
                     VYTNELVDTNTSHRYRVIRMWEQDPEPFLANPALLPFAPLALSESPTRLLEQVAAAVDR
                     IEEPLAFTNISACTQLLAGLRFDKGLIAELFPEDVMQESVIYQKIIQKGHKLGLLEGKR
                     EGLLEGKREGRQEEGYSIVRRLITRRFGSVSDQLQQGIQKLSIAQLEELSEALLDFETV
                     TDLTVWLAEHQQ"
     misc_feature    complement(13131..13144)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.06"
                     /tool="antismash"
     gene            complement(13164..14021)
                     /locus_tag="BJP34_RS24715"
                     /old_locus_tag="BJP34_24720"
     CDS             complement(13164..14021)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008190504.1"
                     /locus_tag="BJP34_RS24715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BJP34_24720"
                     /product="DUF4351 domain-containing protein"
                     /protein_id="WP_070394637.1"
                     /transl_table=11
                     /translation="MAYDNICKYLAENYPADLVKWLHGIEVTKISVLKTELNTEPIHAD
                     SLTLLQTANQILQWEFQTLPVSKPSLPLRMLKYWVRLKEKYNCPIEQVVIFLKSTNSEK
                     AYTNQLLDTNTSHCYRVIRMWEQDPEPFLANPALLPFAPLALSESPKRLLEQVAAAVDR
                     IEEPLAFTNISACTQLLAGLRFDQRLITELFSEDVMQESVIYQKIIQKGHKLGLLEGKL
                     EGRQEEGYSIVIRQLTRRFGSVSEQLQQGIQKLSIAQLEELSEALLDFETVTDLTVWLA
                     EHQQ"
     gene            complement(14118..15560)
                     /locus_tag="BJP34_RS24720"
                     /old_locus_tag="BJP34_24725"
     CDS             complement(14118..15560)
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012946.4"
                     /locus_tag="BJP34_RS24720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BJP34_24725"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_070394638.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.2e-07, bitscore:
                     30.1, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVVIIGAGMSGICMAIKLKKAKINFVILEKSSRLGGTWRDNNYP
                     GCACDIPAHLYCYSFEMKHDWNQVYPSQPEILKYLQHCTRKYNIYPHIRFNQEVISAHF
                     NAKNSLWYVETAEKETITANILISAWGGLNLPKLPNLPSLETFKGVSFHSARWNHSFDL
                     TDKTVAVLGTAASAVQFIPEVAKKVKQLFIFQRTPNWITNRDDRTYSAQMQWYFKNFPI
                     LMQLHRGLLYLRNDLINFPLFTTGSSIGKNLQKQLKKRIHQEIDDSRVRDAVMPSYQPG
                     CKRILINNDFYQTLNRNNVELITDKIESITTDSLVTEPGKDYKVDAIIYATGFNYLSYK
                     KIDIRGSNAESLADIWGNEPEAYLGISVPKFPNFFSLLGPNTGLGHSSVILMVECQVNY
                     IIGCLNKMLREDCKSLEVKEEAMRRYYQDLWKTMEKRVWTKENCMSWYQNKDGRVFALW
                     PGNTIQYWWATRKPVFDDYIST"
     misc_feature    15764..15781
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: strong, score: 21.47"
                     /tool="antismash"
     misc_feature    complement(15766..15781)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.36"
                     /tool="antismash"
     misc_feature    complement(15767..15784)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.54"
                     /tool="antismash"
     gene            15814..16794
                     /locus_tag="BJP34_RS24725"
                     /old_locus_tag="BJP34_24730"
     CDS             15814..16794
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008052700.1"
                     /locus_tag="BJP34_RS24725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BJP34_24730"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_070394639.1"
                     /transl_table=11
                     /translation="MGSLEGKITLVTGASRGIGKGIAIGLGEAGATVYITGRSLDSSNV
                     TEGVSGSLRETQLAVQDAGGICIPVMVDHSDDQQVRLLFERIQDEQKGQLDLLVNNAFS
                     GVQALKDGYEKPFWECPENVWDAVNHVGLRSHYIASVFAARLMIQRQQGLICTISSWGG
                     MSYIFGAAYGAGKAACDRLAADMAVELKPYNVTSLSIWPGIVGTEHISSLALQMAEDKP
                     GNQQSRVISQGFNWETPLLTGRVIAALAADPTVIRFTGRVRVVAELADHYGIIDKDGLR
                     PVSLRSLRFIAPMLWPPLIKYASLIPNINIPWFFLLWGILQSPKI"
     gene            16822..17607
                     /locus_tag="BJP34_RS24730"
                     /old_locus_tag="BJP34_24735"
     CDS             16822..17607
                     /NRPS_PKS="Domain: PKS_KR (7-166). E-value: 4e-12. Score:
                     38.4. Matches aSDomain:
                     nrpspksdomains_BJP34_RS24730_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008190499.1"
                     /locus_tag="BJP34_RS24730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BJP34_24735"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_070394640.1"
                     /sec_met_domain="adh_short (E-value: 1.9e-30, bitscore:
                     105.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNLHGAVVLITGAAGGFGQELTRQLLESGSRLILTDLDKTILKE
                     RAEAIQREVKTGDILALMGINLSERDGCETLYRQVKDLEIEIDILINNAGIGLFGRMDE
                     VPGEKWESLMQVNLLAPMRLSSLFAADMIRRRQGHIVNISSAAGWIAPAGMAHYAASKF
                     GLRGFSEGLLNEVKIYNVKVTAVYPFYSRTPIIQSEKYGTLAKENQGLPDYIITDPAKV
                     IGQTIQAIIDNKREVCPDGIAKSISVIKRFFPQLLNWIF"
     CDS_motif       16843..16926
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BJP34_RS24730_0001"
                     /evalue="1.40E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="BJP34_RS24730"
                     /protein_end="35"
                     /protein_start="7"
                     /score="24.2"
                     /tool="antismash"
                     /translation="VVLITGAAGGFGQELTRQLLESGSRLIL"
     aSDomain        16843..17319
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BJP34_RS24730_PKS_KR.1"
                     /evalue="4.00E-12"
                     /label="BJP34_RS24730_PKS_KR.1"
                     /locus_tag="BJP34_RS24730"
                     /protein_end="166"
                     /protein_start="7"
                     /score="38.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVLITGAAGGFGQELTRQLLESGSRLILTDLDKTILKERAEAIQR
                     EVKTGDILALMGINLSERDGCETLYRQVKDLEIEIDILINNAGIGLFGRMDEVPGEKWE
                     SLMQVNLLAPMRLSSLFAADMIRRRQGHIVNISSAAGWIAPAGMAHYAASKFGLR"
     CDS_motif       17248..17316
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BJP34_RS24730_0002"
                     /evalue="2.30E+01"
                     /label="PKSI-ER_m5"
                     /locus_tag="BJP34_RS24730"
                     /protein_end="165"
                     /protein_start="142"
                     /score="-1.8"
                     /tool="antismash"
                     /translation="ISSAAGWIAPAGMAHYAASKFGL"
     gene            complement(17670..17828)
                     /locus_tag="BJP34_RS44405"
     CDS             complement(17670..17828)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BJP34_RS44405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158517453.1"
                     /transl_table=11
                     /translation="MGFSHHPTLACPYSLFPKTPFFSCSLFPIPVFPFPIPRSAAPCSL
                     KESTPPN"
     gene            complement(17902..18808)
                     /locus_tag="BJP34_RS24735"
                     /old_locus_tag="BJP34_24740"
                     /pseudo=""
     CDS             complement(17902..18808)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008190504.1"
                     /locus_tag="BJP34_RS24735"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="BJP34_24740"
                     /product="DUF4351 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAYDNICKYLAENYPADLVRWLHGIEVTEISVLKTELNTEPIHAD
                     SLTLLQTANQILQWEFQTLPASKPSLPLRMLKYWLRLREKYNCPVEQVVIFLKFTTSSK
                     VYTNQLLESNTSHRYRVIRMWEQDPEQFLANPALLPFATLA"
     gene            complement(18990..19640)
                     /gene="hisIE"
                     /locus_tag="BJP34_RS24740"
                     /old_locus_tag="BJP34_24745"
     CDS             complement(18990..19640)
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /GO_function="GO:0004635 - phosphoribosyl-AMP
                     cyclohydrolase activity [Evidence IEA]"
                     /GO_function="GO:0004636 - phosphoribosyl-ATP diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hisIE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006635030.1"
                     /locus_tag="BJP34_RS24740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BJP34_24745"
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="WP_070394641.1"
                     /transl_table=11
                     /translation="MSASEPTSISQAIPVDQIRYNDQGLVPAIVQDYLDGTILMMAWMN
                     RESLQKTLDTGETWFWSRSRQELWHKGATSGHLQRIKSIRYDCDSDALLVTAEQIGDIA
                     CHLGERSCFHRVEGKKVAPPADTLSQLFEIICDRRDHPVEGSYTCKLFKGGDNKILKKI
                     GEEAAEVVMACKDDDPDAIASEVADLVYHTLVAMAYHQVDVRDVYRKLQQRRR"
     gene            19945..21252
                     /gene="hemL"
                     /locus_tag="BJP34_RS24745"
                     /old_locus_tag="BJP34_24750"
     CDS             19945..21252
                     /EC_number="5.4.3.8"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0042286 - glutamate-1-semialdehyde
                     2,1-aminomutase activity [Evidence IEA]"
                     /GO_process="GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (44-349). E-value: 6.6e-71.
                     Score: 231.0. Matches aSDomain:
                     nrpspksdomains_BJP34_RS24745_Aminotran_3.1"
                     /codon_start=1
                     /gene="hemL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008180065.1"
                     /locus_tag="BJP34_RS24745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BJP34_24750"
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="WP_070394642.1"
                     /sec_met_domain="Aminotran_3 (E-value: 4.4e-76, bitscore:
                     255.1, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTTTSFKTTKSQEIFSAAQNLMPGGVSSPVRAFKSVGGEPIVFD
                     RVQGAYIWDVDGNQYIDYVGTWGPAICGHAHPDVIGALHQALDKGTSFGAPSALENVLA
                     EMVIDAVPSIEMVRFVNSGTEACMAVLRLMRAFTGRDKIIKFSGCYHGHADMLLVQAGS
                     GVATLGLPDSPGVPKSATANTLTATYNNLEEVKALFEQYPNEIGGVILEPVVGNSGFIT
                     PVPGFLEGLREVTQKHGALLVFDEVMTGFRIAYGGAQEKFGITPDLTTLGKIIGGGLPV
                     GAYGGRKDIMSMVAPAGPMYQAGTLSGNPLAMTAGIKTLELLKKPGTYEQLETITKKLS
                     EGLLQIAKDAGHTTTGGYISAMFGMFFTGVPVHNFDDAKTSDSSKFTAFHRGMLERGIY
                     LAPSQFEAGFTSLAHTEDDIDRTLAAAKEVISSIKP"
     aSDomain        20077..20991
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BJP34_RS24745_Aminotran_3.1"
                     /evalue="6.60E-71"
                     /label="BJP34_RS24745_Aminotran_3.1"
                     /locus_tag="BJP34_RS24745"
                     /protein_end="349"
                     /protein_start="44"
                     /score="231.0"
                     /tool="antismash"
                     /translation="DRVQGAYIWDVDGNQYIDYVGTWGPAICGHAHPDVIGALHQALDK
                     GTSFGAPSALENVLAEMVIDAVPSIEMVRFVNSGTEACMAVLRLMRAFTGRDKIIKFSG
                     CYHGHADMLLVQAGSGVATLGLPDSPGVPKSATANTLTATYNNLEEVKALFEQYPNEIG
                     GVILEPVVGNSGFITPVPGFLEGLREVTQKHGALLVFDEVMTGFRIAYGGAQEKFGITP
                     DLTTLGKIIGGGLPVGAYGGRKDIMSMVAPAGPMYQAGTLSGNPLAMTAGIKTLELLKK
                     PGTYEQLETITKKLSEGLLQIAKD"
     misc_feature    21779..21793
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.05"
                     /tool="antismash"
ORIGIN
        1 caaccaccct tggcagtact gaatcagggt ctgtatgcga tcgcatactc ctttctgcct
       61 taatttggct gtctcagcac tccgggatgc ctgcagaagc atcaggtcat tttccaataa
      121 tcggatctgt ttgtaaattt cggtttttag ggactgccat cgagagacat aatccagagg
      181 tatgtctgag gcactaatac tagcgatctg agtgataaac agccccttta gtgcttgaaa
      241 ctgctcctga agtgctgatc gggccacatc atcagggtca acttgacagt acatttgttc
      301 tagggcttgt tggaattccc gtaatgcttg atcatgtgat tgagataaca ttgtgagccc
      361 agttagcgta aaattataaa tgtaaagaat tttttctttt taaagacagg gtagttacca
      421 aaccaacaat ttggctctgc ctcttaaata ttggagtaag cttccatctc tttgaacttg
      481 agcatccgga cagcattctg gcttgacgaa aaaggagggt gagaggaagc tttactgaca
      541 ctgactgctt actcagaagg gtttggctgc atcgacaggc ttgccaccct tctgagtcag
      601 cactcatttt cctagacttc ggttttcaat gactccggta tctatttttt ctctgagggg
      661 caaataatta tggacgcgat cgccacctac tctattttga attttaacgt taagattcct
      721 gactggctgc aagattccct aagagccgcc tcatcagcgg cagatgaacc agtcggtgat
      781 catactttgt taatcgctga ggcatttaaa tttgcttacc aactccatga aggtcagtac
      841 cgcaaatcag gagagcctta cattgcccat ccgattgcag tggctgattt attaagggat
      901 ttgggaggca actctactat gatagcggct ggattcctgc atgatgtagt tgaagatacg
      961 gaaattactc cagaagaaat agaatcccgg ttcggagtgg aggtacgaaa tttagtagaa
     1021 ggggtaacca aactatctaa attcaacttc tccagtaaaa ctgagcgtca agccgagaac
     1081 ttccgccgga tgttcctcgc catggcagca gatatcaggg taatcgttgt caaactggca
     1141 gatcgattac ataatatgcg gaccttggaa tacttgaagc cagaaaaaca ggttcagatt
     1201 gcccaagaaa cccgagatat ctttgccccc ctagccaatc ggttaggaat tggtcgcttt
     1261 aaatgggaac tagaagattt agcctttaag tatctcgaaa caaatgctta tcgggaaatt
     1321 cagtcattgg tatcagaaag acgctcagac cgggaacagc gcctgaagga agtctcagaa
     1381 cttttgcgag agcggattca taaaaccggt gttcattgcg ttgatattag tagtcgcccc
     1441 aagcacctgt atgggatata tcagaaaatg cagcgccaga acaaggggtt tcatgaaatc
     1501 tatgatattg ctgccatgcg ggtgattgtg gaaagcaaag aggaatgcta ccgagcctta
     1561 gccgttgttc atgatctgtt cagaccaatt ccaggtcggt ttaaagatta tattggttta
     1621 cccaaaccca atcgctatca atccctccat accggagtga ttgggtttaa tggtcgcccg
     1681 atcgaagtcc aaattcgcac cctggaaatg caccatgtgg cggaatgggg tattgctgct
     1741 cactggaagt ataaggaaac tggtggctct catactacca aattcacggc tgatgatgaa
     1801 aagctgactt ggctgcggca gttattggaa tggcagaaag acctgaaaga tgctcaggaa
     1861 tacatggaaa acatcaaaga taacttattt gatgaagatg tctatgtatt tacaccagat
     1921 ggtgacgtag tcgctttgag tcggggggca actgccgtag acttcgccta tcggattcat
     1981 accgaggtgg gaaaccattg tgctggtgta cgagttaatg gtgagtggcg ggtactcgat
     2041 tgtcctctaa agaatgggga tattgtagaa attctcacca ccaaaaacgc tcaccctagt
     2101 ctagattggc tcaactttgt ggtaacagcc agtgccagaa atcgtattcg gcaatggttt
     2161 aagcgatcgc atcgggaaga aaatgtggct cggggtcggg aactcttaga gaaggaactt
     2221 gggaaaaaag gatttgaagc cttgctcaaa tcagcaccaa tgcaaattgt ggcggagcgc
     2281 tgtaactacc acaaagtaga ggatttactg gctggtctgg gtcacggtgc agtgacgctc
     2341 aactttgtag tgaaacgact acgggaagaa ctacatgctg gtttagacaa tgagccagaa
     2401 gaaagtgaag tgatccaaga gtattctagc tctacctcca ttcatctcca atcccaactt
     2461 cctagtaaga aacatcctat tgctggtgta gaaggactac tgtatcgcct ggctgcatgt
     2521 tgtaacccct taccgggaga atccattatt ggggtagtca ctcgcactaa ggggatttcc
     2581 attcatcggc aaggatgtgt gaatgtggaa aatgttttag gagaaagact agtaccggtc
     2641 agctggaatc ccactgatat cgataacgga cgtccccaaa cctacccagt aaatctgcaa
     2701 attgaagtga ttgaccgggt tggtgtcttc aaagacattc tatctcgctt aagtgaccaa
     2761 aacattaatg tccgtaaagc tcaagtcaaa actcagtatg gcaaaccagc tctaattgac
     2821 ctgtgcattg atcttctcga tcaccaacaa ctcaagtgca gtttcgccaa aatccaacaa
     2881 atgagcgatg tgttaaatat ccggcgtgtt tctcaggtgg aggaatgtaa ttgaaggtta
     2941 taaggtttgg aggttaaagg ttaggaggtt aggaggttag gaggttagga ggttgaacgc
     3001 gcacccgtgg cctttcggcc aaggttagga ggttgaaagt tagaaggttg aaagttagaa
     3061 ggttaacact taacactcaa gattcaacca acagtcaaga ttcaaccaac agtcaagatt
     3121 caacagataa cactcaaaca gtcaagattc aacaaaccac ttctttttct tctgaacgtc
     3181 gtctaggcac ctcataggtg aagaaatcat gggctaagat ggtatttggg aaaattgccc
     3241 gtgcttcttg aagcaaatca tctaacctca ggggatttcc tggagcataa cgaggactga
     3301 aatgggtcat aattagctgt ttgactcctg caccaagggc aacttgagct gccatggtag
     3361 acgtagaatg taagcgctca atagccatct gagcgtcttg atgggcaaaa gtagcttcgt
     3421 gaatcaaaac atccccatcc tttgccagtt caatggcctg ctcacagaag atagtatcgg
     3481 tacaatacac tactttacga ccagtttcgc gtgctccaca caagtcaatg ccctgaacct
     3541 gacgcccatt aggtagggta atcgtttctc cccgtttgag tttaccgtaa agaggaccag
     3601 acggaattcc taatgcgatc gctttttcta cgttaaacct gcccggtcgg tctttttcac
     3661 acactcgata gccaaaggct ggtacacgat gctccagggg tagacagcta acggtaaatt
     3721 cctggtcttc gtagagtaaa ccaggtttta tcgtgtgaac cttgaagggg aatgccaaat
     3781 gggtgcgaga gtattttagg caagcttgga gataactatc taaacccggt ggtccataaa
     3841 tatcaaccct gtcgatgttt cccgctaagc cacagcttgc caacagacct gggataccaa
     3901 aaatatggtc gccgtggagg tgggtaatga acattcgtct gatctggctg gttttcaggt
     3961 cactccgcaa aagttgatgc tgagtacctt cgccacagtc aaacagccag acttctgcac
     4021 gctgaggtaa gcgcagcgct acactggaca cattgcgcga tcgcgttggg actccggagc
     4081 tagttcctaa aaatgtaatt tccacgcagc ctgtttttga atcttcctct atatatagta
     4141 cacagcctga gtctgatcat gcttaatgtg caatgccttt gaacgtattt agggagtagg
     4201 gagtagggag tagggagtag ggagtaggga atcgggaatc gggaatcggg aatcgggaat
     4261 cggcaacagg gaatcggcaa cagggaatcg gcaacaggga atcgggaatc ggcaacaggg
     4321 aatcgggaat cgggaaaaaa tcctgtgtac cttatagtta ttaaaaacgc tgtatttagg
     4381 attgctatat tagcaaatca accaacaaat caaaaaataa atttagtttt tagcattggg
     4441 actacgatac tattgttgtt actgttgtgt tctggagaga aaattacaaa tagaccggga
     4501 gtgatggata tattgtcatt aatttggtag cgataaaagg tttctaagtg gtaagataca
     4561 tccaaatctt gacgactgtt aatatcattt tcagctagtc taggaggcat tccaaacaca
     4621 aaacctaatt cattgccttc tttgcctaaa tcgggaaatg ccatggttat cgcccaagtc
     4681 cagatatcag ctttagcgcc ctttgagcca tccaaaccac tttggcgggg agaggattcg
     4741 gcgttggcat tgatataact gagccaaccc ccaagggcaa aaccaggact aagtcgatat
     4801 ctcccttgta agccaaaccc attagcggaa gtggcggttt gatcaccaaa gggtgcttgg
     4861 gaaaattgac taccagtact gccagtgaca tcaatccctg agttgggttc aggagaatag
     4921 taatggacat aattcaatcc aatccctaaa cgctgatttg gtgttaaggt tagctgagtg
     4981 aaagcaccaa attgaccatt aaatagtcca ttaccttcgg tgggattaga gatactagcg
     5041 gcactaccta aataagctac actgattcta attgagtcat taaattgata acgaatagca
     5101 gctccaccac cttcagctaa gcgataaagg gggttatgta ctccaaaacg ggagagggct
     5161 gaaacgggat tgagggggtc tgtaatctca tcggctgaca gaccggctgc tgcaatatga
     5221 gcttgaatgc gatcgctaat cgggaatcgg taatatagtt cggttatgac aaactcgttg
     5281 tcagtatttg tctcaaagtc atagagagtc atgtctgtgc catcaagggg attattaaat
     5341 tcaggcacat cggtggtatc gattctagtg cgtaacaggt ctttaccggt gaaactggta
     5401 tcaaaggata atagggcaag acctgtgaat gtagtggtca gactatcgtc ttgagtaggg
     5461 ctactgcaac aaggggcagc tttgttatca gtgaagtagt caattaggat aaagtctact
     5521 tcgccattga gcttagtcgt ggtggaaaac tcagttattt caacttcagc agtacgagcg
     5581 gtgacagcat cgaggttacc acgcagtcga gctagttcca cggtaaactc tgattgcaaa
     5641 cgcttgattg cttctaggtc ttctttaaag taggacgatg ccaaattggg agcaagaatt
     5701 atcttactga gctgatcgaa acaggcattg agagcagcag caaactcata acggttgagg
     5761 ggacgattgc cacgatagct accatcagga tatcctgcca tacaaccgta gcgctctacg
     5821 atggattgta aggcttggaa tgcccaatct gtgggctgga catccgataa ctgggatact
     5881 gatgtcacct gagccatcgg ctgatctgtc tgttcgatat tgggttcgat attgggagtt
     5941 agttcattct caaactcttg tgtacttgtt ggtaattccg ttattggtga tcctgggaac
     6001 aactgggaaa caggtgtcac ctgctccatc acgcccacag agatgggggg aagtaactct
     6061 actgctacgg ataattcctg agcggttgtt gactttggtt gagattcatt ggctagacca
     6121 tggggagtta gtagaaacgc tgcagcgatc gcagctggag ttacatgggg caagctccaa
     6181 gtaagtttga gcattgggaa cgatagttga ctactcacac cgaaactaag gtgggcgcct
     6241 cctagggcgc gagggattgc tcccttggag gcgcccacct cattgtatga tcgcgcaaat
     6301 ataggcaatt tgcccagtag gatgatggta ataggggtag tttttttaga ttagggttaa
     6361 gcagaaagtg tggggggaaa ggagttagat atccaaccgc tgttgttaca ctcaaattga
     6421 ttcgaactgg cttataccga ttgtcttatg aataaccgct tacgtcaatt ttatcaattt
     6481 tttttaaata atgtagtctt agctatagtg gtaggactct taactaatgc tattggagct
     6541 tggatagccg aattattaaa taatcaagaa tcgtttaagc agtataaagc ctttagtatg
     6601 ttggttttta tattatttac acccatagct agtaagtatt tatttaaaat attaaattta
     6661 gcactgaata aaatagcgtc agttagctta atcatattac tgatggtagt ggaagcaagt
     6721 ctatttagcg ttcttcccac taaaacagta aaattacctg aacaatttga caattaccca
     6781 gacatcgcac aagtttttga aatcaaaaat ataggtaagc ctaatagttt aaagaaagtc
     6841 tcgatacata aagcggaagc aagaggtata attagaaaat cactgcttca acctaatgaa
     6901 ttacacttgt tgcttagtga tgtggaattt atcaagtacg aaaaaacttt cagagaactt
     6961 atcgatagaa actatcgagg atatatccaa tacaatatta attacaagcc tgattgtatt
     7021 ggaaattttg aaatggaatc tcaaatagtt gactattcct ttagacctgg tagtggaatc
     7081 ttatcctttg tgataggatt tatagaaaca gaatatttgg tgcctcgaca acgaacttat
     7141 gttattaatc taatagagga cattattaga gataaccaag ttttagaaaa aatcaaataa
     7201 atatgactaa gctgttaagc tttaatgcct aacagcttaa ccaattattc aagggttatg
     7261 gtcttaggta aatcaattac aaagttcagc ccttttggag taacatcggc gttaatagaa
     7321 acgccagcat taacaagttt atctagggtt aatccatagg gtttcaactg tttatcaaca
     7381 cctgcatctt taagatagga aattaaattg acaccatcaa aatttgccaa acccttcttg
     7441 accgctttaa ctgtttgatt gcgaaataca ccttcaagaa gagtcagagc atcagaatac
     7501 catccccgtc cacgtacatt atggttacgg taagcaactt ctaaatcgtt attacgtata
     7561 gcaataccaa gactgacatc accactaggt gttacagaaa agagacgagt acacttcctg
     7621 ccaacacctg gaatcttgat gcattcatac ttacgcaaat tgacggtaaa ggaaaatgtt
     7681 gctccaccat tgtcaataga ctgaagatta atatcgttta tcttccactt gttataacga
     7741 gtattcttga tgtaataccc atcatattga ttgatagagt taactaaatc ttcccggaat
     7801 ttttcaattg gcaacgttcc tcgaatttgt gctttggtta agtccaactc aatgggaaat
     7861 ccaatctgat tggtgaatac gtctagagat tgggcaacga ggggaacatt accatcaggg
     7921 aattggctct ctgcatgaag atcaccagcc agagcaatgg ttaaacctaa agatatggaa
     7981 aaagtactaa aaatagttgc tagagtttta tccaacatat cctctccttt gtcggtatca
     8041 gctagtgttt attggtattt tgaaacctgt ggagactaaa attagctgaa cgcctttata
     8101 taacaagcca atagtttcat taggcttgaa ttatttaaac ccctggaaat actaataaaa
     8161 tagcaaatca atagatgccc atttactgct caggcttcga gttaattttg agcctagttg
     8221 ttttcaaata ccactattta tttctcaggc aaagttcagg aggttatgca atacttaaca
     8281 aaagttaata aaaaagaagc attagggaca gtagaaagga attatagaca ttgaagtata
     8341 gttatggaaa gggtaatagt taataatcaa cagcggatat ggtaacaaaa atatgtctta
     8401 acttttactt cgactgctat aaaattaaac attaaacctt caaccttcaa ccttcaacct
     8461 tcaacctcca acctctaacc ctcaaccctc aatagaataa acccttcctt tccaaccacc
     8521 accccttcct tgccaatgtc gccatgctga atcgatggtc attagcgtat acagcaaccc
     8581 gatcccaggt aagcaaaatc ccagcagagg agaacattga tagagacgca gtgtgggtaa
     8641 gtaagctaaa gccatcagta accatgtcac cagagatgcg atcgcattca gccaatgtcc
     8701 agtcaaaaca ctaacgatca aaccaatcgg aggtactaga taaattaaga tcattcccat
     8761 caccgtacct actaatagcc atggggaata ctctagttgg gtaaaggcgg tgcgagcaat
     8821 catattccag atactggcta aagaaggata tggtcgtaag ctgcgggttg attgacttag
     8881 ccctaaccaa atcccaccaa agccagggct ttgctgattg gttttgctaa agccccctaa
     8941 atcccccaac tttgcggtgc gacccaaggg cgatttactc gccctaggag gcgcgcaccg
     9001 gaagggactt tgagagtttt gttcccccca gcgagggatt gctcgctggg gggctagggg
     9061 ggcgaaactt gttgtattac tagatttaac cgcttgagcg agggcgcaat catcgattaa
     9121 tgcttgacgc actacctcaa tcccaccgat ccggtttaag gcttgatggc taattaaaat
     9181 acatcctcca gccgcagcgg cagtggattt tgtggggtta ttgacccaag caaagggata
     9241 cagtttttga aagaagaaga caaaagcagg aataagtagt cgttcccaaa agtcttggca
     9301 tctgagcaac accattaggg aaactagatc caagtgttcc atctccgctt tggtaaccag
     9361 ttgacggaga ttggctggat catggtcaat atcagcatcg gtaaataaaa aataatctgg
     9421 agcaggggtt tgctgctgcc catgacgaat cccttgttct aaggcccaga gtttaccagt
     9481 ccagccaggg ggtaactctt gaccagataa tacttctagt tggaatcgtt cggaggattg
     9541 gttgctttcc tgggcaaggg cttgagcaat ggtggcagtt tgatcagtgc tttggtcatc
     9601 cactacaatc accgtcaagc agccagcata gtcttgagcc aaaagcgatc gcaatgtcgt
     9661 ggggagcaac tcagcttcat tacgagctgg aattacagca caaactttcg gtaaggattc
     9721 cccttgacct agagacctgg tagggaattt ctctataacc agccgttggt ctgctcgcca
     9781 aaactgaccg cgaaatccta gtaatccgat ccaaatccct aaggatagaa cagtgattgc
     9841 taatccgatt gtatccattt gtattgatac ctattgctaa ttctccacta caagtagcaa
     9901 aatagcgtaa ccaaaggtgc gatccgaggc cgcgagggat tgctcgcggc ctcggaggcg
     9961 cgcacctatg aatgtggtgt gtgaagtaga acggtaaaac atgcaaatcc aagaccggat
    10021 tgtacactca ggggttacag aagcgatcgc aaatagccaa agctatctac tcgctcagca
    10081 atatcccgat ggttactggt gggcagaact agaatctaat gtcaccataa cggcggaaat
    10141 tatcctactc cataaaattt ggggaactga caaacaacga cctttacata aagccgaagc
    10201 ctatctgcgt tcacaacagc ggaaacacgg tggctgggaa cttttctatg gcgatggtgg
    10261 gcatttgagt tgttcggtgg aagcttatat ggcactccgc cttttggggg tacccgccag
    10321 cgactcagct ttggtccgag ccagggattt tattctcaga cggggtggca tcagcaaaac
    10381 ccggattttc accaaatttc atttagcctt gattggctgc tatagctggc gcgggattcc
    10441 ctcgattccc ccctggataa tgttgtttcc gcaatggttt ccctttacga tctatgaaat
    10501 gtctagctgg gcaaggggaa gtacagttcc tttattaatt gtctttgacc agaagccagt
    10561 atttgatagt cagccaagga tcaatctaga cgagttatat accgaaggag ctgatcacgc
    10621 caagtttgag ctacctcgca attctgattg gacagattta tttgtactcc ttgatgatgg
    10681 atttaagtta gcagaagact ggaatttagt tccatttcgg aagcagggac tggcagcagc
    10741 ggaaaaatgg gtcttggaga ggcaagaagc cacaggagac tgggggggaa ttattccagc
    10801 catgttgaat tccctgttag cgttgcgttg tctcaactat gatcttgctg atccggtcgt
    10861 gcaacgggga ctggaagcca ttgatcgctt tgccattgaa acccctgaca gctaccgagt
    10921 ccaagcctgt gtttccccag tttgggatac agcttgggta ttacgagcca tggtggaatc
    10981 tggtttagac ccggatcatc cagccttagt tcggggtgga gaatggttgt tgcagcagca
    11041 aatactagac tatggggatt gggtggtcaa gaatccccaa gggaaaccag gaggatgggc
    11101 ctttgagttt caaaaccgtt tctatcccga tttagatgat tccccagtgg tgattatggc
    11161 cttgaatagc ttgaaactgc ctaatcagaa actgaaacgg gcagccatag ctcgtggctt
    11221 ggcttggata gcatcaatgc agtgtaacca aggaggttgg gcggcctttg atattaataa
    11281 taatcaacac tggctgaatt ctctgcccta tgctgacctg aaagctatga ttgaccctaa
    11341 cacagcggat gtgaccgcac gggtcctgga aatgctaggt tcgtgtaatt tatccataga
    11401 atcccagcag ttagagaaag cgatcgcatt tttgattcag gaacaggaag ccgatggcag
    11461 ctggtttggt cgttggggag ttaactatat ctatggcacc agtagtgctc tttcagcctt
    11521 gtcaaagata gcgcctcaca cccaccaacg tagtatcgaa cggggtgccg cttggctagt
    11581 gcaatgtcaa aaccttgatg gtggctgggg tgagacctgt cttagttacg atgatcccag
    11641 tcttaaggga gtaggaatca gtaccgcatc tcaaaccgct tgggctttaa ttggtttaat
    11701 ggcagcagga gaggctactg gcaactgggc aatggatgcc attgagaagg gagtcaacta
    11761 cttagtgtca actcagcagc ccgatggcag ttgggatgaa accgagttta caggcacagg
    11821 ttttcccagt catttttatt taaagtacca cttctatcaa caatatttcc ccttgttggc
    11881 cttgggaaga tatcaaatgt ctgtttcaag ttgaacgttg tttgtcagaa tgaaaaatta
    11941 agaatgaaga atgcagaatg aagaattaag aaggcagaat ggtgaaggca gaaggcagaa
    12001 ggcagaaggc agaatggtga aggcagaagg cagaaggcag aaggcagaat tcccaattct
    12061 aaattcccaa ttctaaattc ccaattctaa attcccaatt cttaattctt aattctaaat
    12121 tcccaattct taattcttaa ttcttaattt ccacgcatcc tatttattgc tgatgctcag
    12181 ctaaccatac cgtcaaatct gtgactgtct caaaatccaa cagcgcctcg ctcaactctt
    12241 ccaattgagc tatagaaagc ttttgaatcc cctgttgtag ctggtctgaa acactcccaa
    12301 accgacgggt gatcagacgt ctaacgattg agtaaccttc ctcttgcctt ccttcacgtt
    12361 ttccttcgag taaaccttcc cgtttgcctt caagtaaacc cagtttatgt cctttttgaa
    12421 ttatcttctg ataaattaca gactcttgca tcacgtcctc cggaaataat tctgctatca
    12481 accctttgtc gaaccgcaaa ccagctagta actgggtaca agcggatatg ttagtaaaag
    12541 ccaatggttc ttcaatccta tctactgctg ccgccacttg ctctaataat cttgtcgggg
    12601 actcactcaa tgccagagga gcaaagggca ataaggcggg attggctaaa aatggctcag
    12661 ggtcttgctc ccacatcctg attactcgat agcgatgact ggtgttagta tcgaccaact
    12721 cgttagtata aactttttct gagcgagtga atttcagaaa tatcaccacc tgctctatgg
    12781 gacagttata cttttctttg agtctgaccc aatacttgag catccgcaat ggtagggatg
    12841 gcttggaagc cggtaaggtt tgaaattccc agtgcaggat ttggttagcg gtttgcagca
    12901 aggtcaagga atccgcgtga atcggttcgg tatttaactc agttttgagc actgatattt
    12961 cagtaacttc aataccatga agccacttga ccaaatcagc tgggtagttt tcggcgagat
    13021 atttacagat attatcgtaa gccaaggtag ttatctatgg ttaacagtac ctgggccagt
    13081 ttaccggatt tggtaaaaaa aagcgttccc gtagcggctc ttgcagagca tcgcgtagcg
    13141 tggccgtagg ccaatcgcat tttttattgc tgatgctcag ctaaccatac cgtcaaatct
    13201 gtcactgtct caaaatccaa cagcgcctcg ctcaactcct ccaattgagc aatagaaagc
    13261 ttttggatcc cttgttgtag ctgctcagaa acactaccaa accgacgggt cagttgacgt
    13321 ataacgattg agtaaccttc ctcttgcctt ccttcgagtt tcccttccag taaacccagt
    13381 ttatgtcctt tttgaattat cttctgataa attacagact cttgcatcac gtcctccgaa
    13441 aataattctg tgatcaaccg ttggtcaaac cgcaagccag ctagtaactg agtacaagcg
    13501 gatatgttag taaaagctag tggttcttca atcctatcta ctgctgctgc cacttgctct
    13561 aataatcgtt taggagactc actcaatgcc agaggagcaa agggcaataa ggcgggattg
    13621 gccaaaaatg gctcagggtc ttgctcccac atcctgatta ctcgatagca atgactggta
    13681 ttagtatcga gcaactgatt agtataagct ttttctgagt tagtggattt cagaaatatc
    13741 accacctgct ctatgggaca gttatacttt tctttgagtc tgacccaata ctttagcatc
    13801 cgcaatggta gggatggctt ggaaaccggt agggtttgaa attcccactg caatatttga
    13861 tttgccgttt gcagcagggt caaggaatcg gcgtgaatcg gttcagtatt taactcagtt
    13921 ttgagcaccg agattttagt aacttcaata ccatgaagcc acttgaccaa atcagctggg
    13981 tagttttcgg cgagatattt acagatatta tcgtaagcca aggtagttat ctgtggttaa
    14041 cagtacctgg ccgagtttac aggatttggt caaaaaaagc gatgctctca aagagccgct
    14101 acgcgaacgc aactaagcta ggtagaaata tagtcatcaa aaactggttt tcttgtagcc
    14161 caccaatatt ggatagtatt accaggccac aaagcgaata ctctgccatc tttattttga
    14221 taccaactca tacagttttc ttttgtccaa accctctttt ccatagtttt ccataaatcc
    14281 tgataataac gtctcatggc ttcctccttg acttctagag atttacagtc ttctctgagc
    14341 attttattca agcagccaat aatataatta acttggcact ctaccattaa aataactgag
    14401 ctatgaccca aaccagtgtt cggtcctaaa agactaaaaa agttagggaa cttaggaaca
    14461 gaaataccaa gatacgcttc tggttcgttg ccccatatat ccgctagact ctctgcgttg
    14521 ctaccacgta tatctatttt tttgtaggac aaatagttaa atcctgtagc atagataata
    14581 gcatcaactt tatagtcctt tcctggttcg gttaccagac tatcagtagt tatgctttct
    14641 atcttatctg taatcaattc tacattattt cggttcaggg tttgataaaa gtcgttatta
    14701 attaaaattc gtttacaacc tggttgatag ctgggcatca ccgcatcccg tactcgggag
    14761 tcatcaattt cctggtgtat acgttttttc aattgttttt gcaggttctt accaatagaa
    14821 cttccagtag tgaatagggg aaaattgatt aagtcattac gtaagtatag taatccccgg
    14881 tgcagttgca tcagaatagg aaaattttta aaataccatt gcatttgggc tgaataagtc
    14941 cgatcgtctc ggttagtaat ccagttagga gttctttgaa aaatgaatag ttgtttgact
    15001 tttttggcaa cttctgggat aaattgaact gcactggctg cagttcctaa aactgccacc
    15061 gttttatcag ttaaatcaaa gctgtggttc catctagctg agtgaaacga gactcctttg
    15121 aaggtttcca agctaggcaa attgggtaat ttgggtaaat ttaaacctcc ccaggcacta
    15181 atcagtatgt tagcagttat agtctccttc tcagctgttt caacatacca tagggaattt
    15241 ttggcattga aatgggcgct aatcacctct tgattaaaac ggatatgggg ataaatattg
    15301 tatttacgtg tgcagtgttg taagtatttc aatatctctg gctgagaggg ataaacttgg
    15361 ttccaatcat gtttcatttc aaaagagtag caatataaat gagcgggaat gtcacaggca
    15421 catcctgggt agttattatc ccgccaagtc cctccaagtc gagaggattt ttctagtata
    15481 acgaaattta ttttggcttt tttaagttta atagccatgc agataccaga catgcctgca
    15541 ccgataataa ctacttgcat tttttcgatt ttaagaggat agttaatggg aaaaatttgt
    15601 tttattattt agttcgatat ttacgataat cgactaatag agagaaatag taaccataaa
    15661 attcccaaac aatgctagca tgaattaaga gcaaaatcca aaaaaataat tatggtaagc
    15721 ctttagcaat aatcgatatt tagagataaa ttttaaccat aaaatgttaa aaatatgtta
    15781 acatgaatta agtcaatatc aaaaaaagta attatgggaa gccttgaagg taaaataacc
    15841 ttagtcacgg gtgccagccg tggtattggt aaaggaattg cgattggcct tggcgaggca
    15901 ggtgctacgg tatatattac tggtcgtagt ctcgacagtt ccaatgtcac agagggagtt
    15961 tccggtagtc ttagggaaac ccaattagct gtgcaagatg ctggtgggat ttgtattccg
    16021 gtcatggtag atcatagcga cgaccaacaa gtgcgcttac tctttgaacg gattcaagac
    16081 gagcagaagg gacaactgga tctgctggtc aataatgcct tttcaggagt gcaggcattg
    16141 aaggatggat acgaaaaacc attttgggaa tgccctgaga atgtttggga tgctgtcaat
    16201 catgtcggtc tccgcagcca ttatattgcc agtgtttttg cagctcgact gatgattcag
    16261 cgtcagcagg ggctgatttg caccatctca tcttggggcg gcatgtctta catctttggt
    16321 gccgcctatg gagcgggtaa agcagcttgc gatcgacttg ctgctgatat ggctgttgaa
    16381 ctcaagccat ataatgtgac gtccctttcg atttggccag gcatagttgg taccgaacat
    16441 atttccagtt tggctttgca aatggcagaa gataaaccag gtaatcagca aagccgagtg
    16501 atatctcaag gctttaattg ggaaactcct ttactaacag ggcgcgttat tgctgccctt
    16561 gctgcggacc caactgtaat ccgctttaca ggccgtgttc gagttgttgc agaactggct
    16621 gatcactatg gaattatcga taaagacggg ttacgtccgg tatcactacg ctctctacgt
    16681 tttatagctc caatgttgtg gccaccatta ataaaatatg cgtcgctgat acctaacatt
    16741 aatataccct ggtttttctt actatgggga atactccaat ctcctaaaat ttaaccgata
    16801 gcaaaaattg ataacaatta aatgagcaat ctccatggag ctgttgtact gataaccggt
    16861 gccgccggtg gattcggtca ggaactgact cgacaattat tagaatctgg tagccgtttg
    16921 atcctcacgg atcttgataa aactattctt aaagagcgtg ccgaagctat tcaacgggag
    16981 gttaaaactg gggatatact tgcccttatg gggattaatc tttctgaacg tgacggatgc
    17041 gaaacccttt atcgccaggt taaagacctg gaaatagaaa tcgatatttt gatcaacaat
    17101 gctggaattg ggctttttgg tcgcatggac gaagttcctg gggaaaaatg ggaaagcttg
    17161 atgcaggtaa atctgctggc accaatgcga ttaagttctc tatttgccgc cgatatgatt
    17221 aggcgtcgcc aaggtcacat cgttaacatt tcctctgctg ctggctggat tgcacccgct
    17281 ggcatggctc attatgctgc tagtaaattc gggttgcgag gattcagcga agggctttta
    17341 aatgaagtta aaatttataa cgtcaaggtt acagctgttt atccctttta tagccgtact
    17401 cccattatcc agtcggaaaa atatggaacc cttgccaaag aaaatcaggg gttgccggac
    17461 tatataataa ctgatccggc taaggttata gggcaaacga ttcaagcaat tattgataat
    17521 aaacgtgaag tttgtcctga tggaattgca aaaagtatct cagttattaa acgttttttt
    17581 ccccaattat taaactggat tttttaaact ggatttttaa tgggttcaac cggaaaccaa
    17641 aagccgattt ataggattta taccatttat taattgggtg gggtactttc ttttagggag
    17701 cagggagcag cggatctggg aatagggaat gggaaaaccg gaatagggaa tagggaacag
    17761 gaaaaaaatg gtgttttagg gaatagggaa tagggacaag caagggttgg gtggtgcgag
    17821 aagcccacac ttaaaaccca cacttacaag ggtaggaagt gtgggagcat ggcactgagc
    17881 tttgatgcgt acgcatccga tttattgctg atgctcagcc aaccacacag ctacatcggt
    17941 gactgtctca aaatccaaca gcgcctcgct caactcctcc aattgagtaa tagaaagctt
    18001 ttgaatcctc tcaagtagct ggttctcaac attaccaaac cgacgggtca gttgacgtat
    18061 aatgattgag tacccttcct cttgccttcc ttcacgtttt ccttcgagtt ttccttcacg
    18121 ttttccttcg agttttcctt cacgttttcc ttcgagtaaa cccagttgat gtcctttttg
    18181 aattatcttc tgataaatta cagactcttg catcacttcc tccggaaata attctcctat
    18241 caaccctttg tcgaaccgca agccagctag taactgcgta caagcggaga tgttagtaaa
    18301 agctagtggt tcttcaatcc tatccactgc tgccgccact tgctctaata atcgtttagg
    18361 agactcacgc ttatgctaaa gtagcaaaag gcaataaggc gggattggcc aaaaattgct
    18421 cagggtcttg ctcccacatc ctgattactc gatagcgatg gctagtgtta ctctccagca
    18481 actggttagt ataaacttta gatgaggtgg tgaacttgag aaatatcacg acctgttcaa
    18541 caggacagtt atacttttct ctgagtctga gccaatactt gagcatccgc aatggtaagg
    18601 atggtttgga agccggtagg gtttgaaatt cccactgcaa tatttgattt gccgtttgca
    18661 gcagggtcaa ggaatccgca tgaatcggtt cggtatttaa ctcagttttt agcaccgata
    18721 tttcagtaac ttcaatacca tgaagccacc tgaccaaatc agctgggtag ttttcggcaa
    18781 gatatttaca tatattatcg taagccaagg tagtgatcta tggttaacag tacctgggcc
    18841 agtttaccgg atttggtaaa aaaaagcgat gctctctcac agacgcgatc gcatccatgg
    18901 tgattggcct tttggcttct ttctataatt aaaatctgct gcaatcacca attacctttt
    18961 ccccaattat taaagtggat tgtctaacac tatcgacggc gctgttgcaa tttgcgataa
    19021 acatcccgta catcaacctg atggtaagcc atagcaacta gggtgtgata gaccaagtcc
    19081 gctacttcag atgcgatcgc atccgggtca tcatccttac acgccattac cacttctgca
    19141 gcttcttccc caattttttt aagaatctta ttatccccac ccttaaacaa cttacaggta
    19201 taggaccctt ctacgggatg gtcacggcga tcgcaaatta tctcaaacaa ctgagacaag
    19261 gtatctgctg gaggggctac tttcttaccc tccactcgat ggaaacagct acgctcaccg
    19321 agatggcagg caatatcacc aatttgttcc gccgtcacga gtaaagcatc actgtcacag
    19381 tcgtagcgga tggattttat cctttgtaaa tgcccagatg tagcaccctt gtgccacaat
    19441 tcctgacgag agcgactcca aaaccaggtt tctcctgtat cgagggtttt ttgcaatgac
    19501 tcccgattca tccaagccat cattaatatc gtaccatcta ggtaatcttg gacaatggct
    19561 ggcactagtc cttgatcgtt gtagcgaatt tggtcaactg gtatagcttg gctaatggaa
    19621 gtcggttcag atgctgacat agttttaggg caacagattg aaacacccag cgggtcaaac
    19681 agctttaatg agatacaccc tacaagatac cacccctgac atccaattga tcactaaata
    19741 gtgatcagta aatctggatt ctttctttac aaattcaaaa cggatcagtc tccataggat
    19801 aataatctct tgtccagtat tgcccctaag ccgaagttac ctgatccgaa gttccctatt
    19861 gccctgttta aggggggtaa tggggttaga gctttttacc ttattttcaa ctaacccgta
    19921 cattattgat attaggagac tattttggtt accaccacct cgtttaaaac caccaaatca
    19981 caagaaattt tcagcgccgc ccaaaaccta atgccaggag gggtcagctc cccagtcaga
    20041 gcctttaaat ccgtaggggg agaaccgatt gtatttgacc gagttcaagg agcatacatc
    20101 tgggatgtag atggaaacca gtacattgac tatgtaggta cctggggacc agccatttgc
    20161 ggtcatgctc atccggatgt tattggggca ttgcaccagg ctctagacaa gggtaccagt
    20221 tttggagctc cctccgccct agagaacgtg ctagcagaaa tggtgattga cgccgttcct
    20281 agtattgaaa tggtgcggtt tgttaattct ggtaccgaag cctgtatggc agtgctgcgc
    20341 ctgatgcgtg ccttcacagg acgggacaaa attatcaaat tttctggctg ctaccatggt
    20401 cacgccgata tgctgctggt acaagctggt tctggagtgg ctactctagg tttaccggat
    20461 tcccctggtg ttcctaagtc tgccactgct aatacgttaa ccgctaccta taacaacctg
    20521 gaggaagtta aagctttatt tgagcaatat cccaatgaga ttggtggggt catcctagaa
    20581 ccggtggtgg ggaattctgg tttcatcact cctgtgcctg gttttcttga aggcttgcgg
    20641 gaagtgactc aaaagcatgg cgctctactg gtgtttgatg aagtgatgac tggcttccgg
    20701 attgcctacg gtggtgctca ggagaaattt ggcatcactc ctgacctgac taccctaggt
    20761 aaaattatcg gtggtggttt gcccgtggga gcctatggcg gacgaaagga tatcatgtcc
    20821 atggtggcac cagcagggcc aatgtatcaa gccggaaccc tctctgggaa tcctctagcc
    20881 atgacagcag gcattaaaac cctggagtta ctcaagaaac cgggtaccta tgaacagcta
    20941 gagactatta ctaaaaagct ctccgaggga ctgctgcaaa ttgctaaaga tgctggtcat
    21001 accactactg gtggttacat cagcgctatg tttggtatgt tctttactgg tgttccagtt
    21061 cataacttcg atgatgccaa aacctctgat tcatccaaat tcactgcttt ccatcggggc
    21121 atgttagagc gtggaatata cctagccccc tcacaatttg aagcaggatt tacctcccta
    21181 gctcacaccg aggacgatat tgaccgcaca ttagcagcag ctaaggaagt catttctagt
    21241 atcaagccat agtagtttag agtttaagct atcagcattc agctctcagc tatcagcatt
    21301 cagctctcag ctatcagcat tcagctctca gctatcagca ttcagctctc agctctcagt
    21361 tagcttatgg gtaacatcac aggctagaag cctgtgccac cccacttgac ttttgaataa
    21421 aataagctga cggctgacgg ctgacggctg acggctgacg gctgataact tacttatcga
    21481 tagttagtaa attgcaaagc aactggcaaa tcttcttgct tcaaccgctg gatgatatct
    21541 tgtaagtcat ccttagattt gctagatact ctaactgaat caccttgaat cgaggcttgc
    21601 acttttttaa attcatctcg aatcaatttg gtgatttttt tactatattc ttggctgatg
    21661 ccttttttta gcgtgatttc ttggcgaaca cgattaccac tagctgcttc tactttacca
    21721 tattcgaaga ttttttgcga aagttcccgt ttcgcagctt tggtacgaag aacagtatgc
    21781 acagcatcta gggtaaagtc actatcagta ttgatggtga tagattcttc tcctaattcg
    21841 acagtggttt ttgtatcttt gaggtcgtaa cgacttttga tttcacgaat agtttgatcc
    21901 acagcattga ccaa
//
