LOCUS       NZ_CP014859            21056 bp    DNA     circular CON 20-NOV-2024
DEFINITION  Actinoalloteichus hymeniacidonis strain HPA177 chromosome, complete
            genome.
ACCESSION   NZ_CP014859
VERSION     NZ_CP014859.1
KEYWORDS    RefSeq.
SOURCE      Actinoalloteichus hymeniacidonis
  ORGANISM  Actinoalloteichus hymeniacidonis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Actinoalloteichus.
REFERENCE   1  (bases 1 to 6306386)
  AUTHORS   Schaffert,L., Albersmeier,A., Winkler,A., Kalinowski,J.,
            Zotchev,S.B. and Ruckert,C.
  TITLE     Complete genome sequence of the actinomycete Actinoalloteichus
            hymeniacidonis type strain HPA 177T isolated from a marine sponge
  JOURNAL   Stand Genomic Sci 11, 91 (2016)
   PUBMED   28031775
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6306386)
  AUTHORS   Schaffert,L., Albersmeier,A., Winkler,A., Kalinowski,J., Zotchev,S.
            and Ruckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAR-2016) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Coverage                   :: 159x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001747425.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 01:17:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,434
            CDSs (total)                      :: 5,374
            Genes (coding)                    :: 5,337
            CDSs (with protein)               :: 5,337
            Genes (RNA)                       :: 60
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 37
            CDSs (without protein)            :: 37
            Pseudo Genes (ambiguous residues) :: 0 of 37
            Pseudo Genes (frameshifted)       :: 3 of 37
            Pseudo Genes (incomplete)         :: 34 of 37
            Pseudo Genes (internal stop)      :: 1 of 37
            Pseudo Genes (multiple problems)  :: 1 of 37
            CRISPR Arrays                     :: 13
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:46:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3464304
            Orig. end                         :: 3485360
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP014859.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21056
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="16"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21056
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21056
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11056](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11056)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(43..636)
                     /locus_tag="TL08_RS15145"
                     /old_locus_tag="TL08_15305"
     CDS             complement(43..636)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="TL08_RS15145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="TL08_15305"
                     /product="hypothetical protein"
                     /protein_id="WP_157421100.1"
                     /transl_table=11
                     /translation="MSSPTDPPVLTLRPTTERRVFTVALAVIISSIFIMPGAVTAGWIG
                     ILVGLAVVAAFVGLVALSRFRPLVVLTRTHLGHRGMFGGIRWIPRSLVKGIVHGPVLLG
                     RTAPHTVFIADEGGRCLLRLMDGTFERADLDRLVAQLPAPVYPLPLRALTPNKLDLLYP
                     GLTSWWERHPIGLAFIILAAVLIVTLCTAVIIAL"
     misc_feature    complement(154..156)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(686..1033)
                     /locus_tag="TL08_RS15150"
                     /old_locus_tag="TL08_15310"
     CDS             complement(686..1033)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="TL08_RS15150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="TL08_15310"
                     /product="hypothetical protein"
                     /protein_id="WP_069849828.1"
                     /transl_table=11
                     /translation="MTNHLLHRYPDAAALPDDNADTHETYQRMRILDRETRRGEAAVSS
                     PTAMRALLAEVAPTADPEWRAIWHSVIDVDERSLTAGFYLGESDSGTIRHSEEIRFPVR
                     NRLDSLAALDV"
     misc_feature    complement(1016..1018)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(1030..1203)
                     /locus_tag="TL08_RS28140"
     CDS             complement(1030..1203)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="TL08_RS28140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157421101.1"
                     /transl_table=11
                     /translation="MAGGGPNDILTTRHLVAKGSQTDIGRALADEAHSRFGWFPRRAAT
                     DFATGRPKARSA"
     gene            1441..1587
                     /locus_tag="TL08_RS28145"
                     /old_locus_tag="TL08_15320"
     CDS             1441..1587
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="TL08_RS28145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="TL08_15320"
                     /product="hypothetical protein"
                     /protein_id="WP_157421102.1"
                     /transl_table=11
                     /translation="MDQTAELAELEATGRFPLLFNATEPPDLQATSEFGLARLLDGLAP
                     LFD"
     gene            complement(1664..2353)
                     /locus_tag="TL08_RS15155"
                     /old_locus_tag="TL08_15325"
     CDS             complement(1664..2353)
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009943405.1"
                     /locus_tag="TL08_RS15155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_15325"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_236750279.1"
                     /transl_table=11
                     /translation="MTLRTRNPFVRSSRVGKSAVSAVLAGAFLLGGQPLLAGATETPAP
                     ASADGGVTAEQDAGAAMAPLYNDVAPTLQFHTLAGEAQAHSARVAEQAAAEAEANRPEF
                     VKPAEGTFTSGYGARWGTNHFGIDIAGPIGTPVVSATDGTVINAGPATGFGQWVRVQAP
                     DGTITTYGHVETFTASVGEQVKAGDQIATIGNRGQSTGPHLHFEVNVGGQKLDPQPWLA
                     ERGITVQ"
     gene            3008..3571
                     /locus_tag="TL08_RS15165"
                     /old_locus_tag="TL08_15330"
     CDS             3008..3571
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024958.5"
                     /locus_tag="TL08_RS15165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_15330"
                     /product="DUF4132 domain-containing protein"
                     /protein_id="WP_069849833.1"
                     /transl_table=11
                     /translation="MTTASFRLAEDRTPTDLDDDAYPLPSGALIGVAHPAMLHDDLTRW
                     AAIFADYEIMQSFPQIGAVVPPLTDEERAGPRLSRFEGSTVPTRALSSLLRRGWHRAEE
                     GPVTMFHRPVAADRRVEIWLDPGYTPGASVNAKEQTLREVRLVCEGTPLSEVRTEAEHA
                     VTQFNVLDEVDCHKIVYDLTQLAR"
     gene            3601..3753
                     /locus_tag="TL08_RS28150"
                     /old_locus_tag="TL08_15335"
     CDS             3601..3753
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="TL08_RS28150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="TL08_15335"
                     /product="hypothetical protein"
                     /protein_id="WP_157421103.1"
                     /transl_table=11
                     /translation="MTDHPVPDENTLVLPEAWYPHLAPRRGGQPIPVVPVPNATEKAAR
                     LVVSG"
     gene            complement(3891..4283)
                     /locus_tag="TL08_RS15170"
                     /old_locus_tag="TL08_15340"
     CDS             complement(3891..4283)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="TL08_RS15170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="TL08_15340"
                     /product="hypothetical protein"
                     /protein_id="WP_069849834.1"
                     /transl_table=11
                     /translation="MLVDAGGGQHFLAHSSVVIDAERLRLSALDRSRISGTHDDRFVGA
                     QLIVEWVPVVMVEFCKRFPRLGTLRCAGKASPALHRRGEAVVIASLAVGLQTMTSCFAD
                     QTCGDGRIESFDDNASTAFVEAGRSA"
     misc_feature    complement(4086..4088)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(4258..4273)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.98"
                     /tool="antismash"
     gene            4308..6632
                     /locus_tag="TL08_RS15175"
                     /old_locus_tag="TL08_15345"
     CDS             4308..6632
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011874407.1"
                     /locus_tag="TL08_RS15175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_15345"
                     /product="sorbosone dehydrogenase family protein"
                     /protein_id="WP_084643058.1"
                     /transl_table=11
                     /translation="MGKRRWWVPVLTAIAVTGTLSIPPTAVGSDSTSAADPADEPITDP
                     IPEKPIQSRLGLVLDEYAQLPESEATPPATDPRLIRHNRINFVGEVPDGSGREYIPDLN
                     GPLYLLDGGDQHVYLDFAAEFEHFFSGRGMGSGFGFVTFHPEFAENGRFYTTHTEDETA
                     IENEEPTYPNQPDSVVQSVITEWTADDPSADVFSGSSREIFRYGFSTYIHAIQQIDFNP
                     TARSGDEDYGLLYLAVGDGGIGVRSDAPQELDNPAGKILRIDPAGTDGPNGNYGIPPSN
                     PFVDTPDALGEIYALGMRDPHRFTWDPERDNAMYLGHIGQHAVEAVYEVEAGDNLGWSE
                     REGDLQYRREDGCYLYPLPEDDAEYDYVYPVAAYDHDPPANWPCDSDSGHAISGGQVYR
                     GELAELRGKYIFGDLVDGKVFYTEVEEMRRGQTRAPLHELQLFDTEGTRLRMSDFVGEG
                     RVDLRFGIDSDRELYLLAKSNGKIWRVVDTKRGAGSEVTRKVERNLVAHYDFENPFAVD
                     GSYEADLGSSNTLLSLINGETDMRVADGAFPGSNNALQVQQIAPEENGNDDWKAGIFDE
                     DGVESFEAFNGVEGTTVMGWFKMTGENPSPNSNTEDPDDYYNAVGLAGILSGSSDGHEV
                     RALLELIQVDGELRLVALGRRIDGAASQTFAAQQDWQELLPQNEWVHLAATFDYTTGEM
                     ALYRNGESIPGFYTRSDDPWEVDGSGTSATDPKGIKIGGSFPQNDREANPCNCRMDSLM
                     FLDTAAAPSTISQQYHRFLRR"
     gene            6831..7643
                     /gene="prcB"
                     /locus_tag="TL08_RS15180"
                     /old_locus_tag="TL08_15350"
     CDS             6831..7643
                     /EC_number="3.4.25.1"
                     /GO_component="GO:0005839 - proteasome core complex
                     [Evidence IEA]"
                     /GO_function="GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0010498 - proteasomal protein catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="prcB"
                     /inference="COORDINATES: protein motif:HMM:TIGR03690.1"
                     /locus_tag="TL08_RS15180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_15350"
                     /product="proteasome subunit beta"
                     /protein_id="WP_172803799.1"
                     /transl_table=11
                     /translation="MTASNNRAGRHLLDPESAALLRLNGSSFYRLLQTCAPQALPEISV
                     PIAPDEAQLPHGTTVVAMHYRDGVVMAADRRATMGNLIAQRDLRKLEPADSHSGIAFAG
                     TVGTAMRLVSLFQLELLHYEKIEGVALSFPAKVNRVSTLIRGNLGPARQGLAVIPLFAG
                     WDDHAGAARVFTFDIGGSASEQREYGGAGSGSTFALGSLKKLYRPELTRSEAIRIVLTA
                     LTDAADEDTATGGPQAPGHLLPLVSCIDESGYAAVPTEEIAAELVAAD"
     misc_feature    6841..6854
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.71"
                     /tool="antismash"
     misc_feature    complement(7649..7665)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.99"
                     /tool="antismash"
     gene            7718..8419
                     /locus_tag="TL08_RS15185"
                     /old_locus_tag="TL08_15355"
     CDS             7718..8419
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010306745.1"
                     /locus_tag="TL08_RS15185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_15355"
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="WP_069849836.1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-05, bitscore:
                     23.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAPPRTDYGHEDLLALLTLMTGDEKHEPSATSTLETIWVLYDRI
                     LRVDPARVDDPGRDRFLLSKGHGPMAYYAVLAAKGFLTTDQLRGFGGFDSPLGYHPDRT
                     LVPGVEIGSGSLGHGLGLAVGTALGLRATGHDDAAVVVLVGDAELEEGSNLEAIQYAGR
                     ARLDRLTTVVIDNSSASLGWPGGIAARFALEGWSTVEVDGRDLDKLEQAFTSAPGDRPH
                     AVIAHVEPKER"
     gene            8419..9354
                     /locus_tag="TL08_RS15190"
                     /old_locus_tag="TL08_15360"
     CDS             8419..9354
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009943247.1"
                     /locus_tag="TL08_RS15190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_15360"
                     /product="transketolase family protein"
                     /protein_id="WP_069849839.1"
                     /transl_table=11
                     /translation="MTSTMDNETITSGENQRDRFYRILPQLLAEDDRLAAVLAEIGASY
                     VDSAAARAVSDRLINVGIREQLLIGVAGGLALTGLRPIAHTFAPFLIERPFEQVKLDLG
                     HQGVGAVLVSAGGSYDWPEGGETHFGYRDVALLDTLQDWTVHVPGHPDEAEALLRTSVR
                     GDGRVYVRLGGDANSRPLAGRDGRMQVLRRGTRGTVIAVGPMADRTVAATEGLDVTVLY
                     AATIRPFDGETLRATLDAPEVVLVEPYLRGTSIAEVTRSLAGIRHRVSGLGIGPAEARR
                     YGTRAEHDVLHGIDEAGLRRQITDFLDAAG"
     misc_feature    8989..8991
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(9423..9866)
                     /locus_tag="TL08_RS15195"
                     /old_locus_tag="TL08_15365"
     CDS             complement(9423..9866)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016001.5"
                     /locus_tag="TL08_RS15195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_15365"
                     /product="nitroreductase/quinone reductase family protein"
                     /protein_id="WP_069849840.1"
                     /transl_table=11
                     /translation="MKAEGLLRSIASAHQTVYQRTGGRVGHRLMIRPTLLLTTQGRRSG
                     KSRTSALVYGTDGADYLVVASNWGTERLPGWLHNLRAGGPAEVLVGRRRVAVTSREVLP
                     EDTDHTRLWDIVNRVNRDLYRRYAKTLKRPLAVIVLTPTDSRG"
     gene            complement(10001..11056)
                     /locus_tag="TL08_RS15200"
                     /old_locus_tag="TL08_15370"
     CDS             complement(10001..11056)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012705.5"
                     /locus_tag="TL08_RS15200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_15370"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_069849842.1"
                     /sec_met_domain="phytoene_synt (E-value: 6.3e-41, bitscore:
                     138.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.2e-26,
                     bitscore: 92.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALHAAPTRRLDPLLRDSYALCRRLHATHRPTYLAARLLLPPAIR
                     PQVHAVVAFFAASDRVADVGDPRMRERAFRHWSAAAVSELRRGESRHPLRRALIDTTRR
                     HGLEPELFIRFLEATRADSRGAAEFATFDDLRVFLRGVSGTAALVGARLLCTPSPELDR
                     LASLIGEVHQLIDIFCDFAEDLPQGRVYLPAEDMERCEVDRATVRRGVVGPELDALVRL
                     QVSRARELHLESTRITSLVPARFQPFARAALEIHRRYLDVVDHLGSRVLREGASLSKAR
                     LLRLALPHVLGGRLAGGTRRAGPGGHRPLGVSTWPAALQRGDRARPAVDVDLFEDHRSR
                     PSGRGGRRFRS"
     gene            11514..12263
                     /locus_tag="TL08_RS15205"
                     /old_locus_tag="TL08_15380"
     CDS             11514..12263
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020674123.1"
                     /locus_tag="TL08_RS15205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_15380"
                     /product="maleylpyruvate isomerase family
                     mycothiol-dependent enzyme"
                     /protein_id="WP_069849844.1"
                     /transl_table=11
                     /translation="MHTTTEFIETLHREGERFADTAEHVDLTAPVPGCPAWSVRDLVLH
                     LGAVHRWATGYVVEGRTQPEPIAEAPALEDTELAPWLRDGHARLVAALTEAPAELDCWT
                     FLPTGVEPLEFWARRQAYETSVHRVDIEAASGLALSPMAPEFASGGIDEFLRGFQARPS
                     SPVRTETPKTLRILPTDVPAAGWTVSLSADKPPRTERTRDGQPADCTYTGPAMALYLVL
                     YNRLPIDAVQCGGDVSLAQRWRDLTSS"
     misc_feature    11757..11759
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12612..12627)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 21.15"
                     /tool="antismash"
     gene            13092..14381
                     /locus_tag="TL08_RS15210"
                     /old_locus_tag="TL08_15385"
     CDS             13092..14381
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024808.5"
                     /locus_tag="TL08_RS15210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_15385"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_069849846.1"
                     /transl_table=11
                     /translation="MLKRRDALRILGLSAVLGSGSLGLAGCGSSGDGANGPLRVALVNH
                     VWTSAIRERIAEFEDLTGRRVLVSTMTSDQLSSTYNVKLNASAPDLDVMMYRPLQEQLL
                     FARNGWLTEFNDLVADDSEYDWADVQDGPKDRVTIDGRIFGVPIITERPTLYYRRDLVD
                     APPTTLEEMYETARRLHSPDTGLHGFTGRGQRAGAVSMFSSYLYSHGADFIVDGRSGVG
                     SPEALAAYEYYGRLLREAGPIGATNMTLEQITPIFAQGKAVFAIDADAVYQNFIDPATS
                     TVGDRTGFAAFPAGPAGSRPFNIASWGLTINAFSERRDIAWEFIRWASGPEMTLRLQNE
                     GVPSARTSAWADEASLTAFPPDLAESMAAGIETGVGADRPDVVQVGRARDIVGRPIVAS
                     ILGDDVAASARDASEEFDEFLVRDARQRQL"
     misc_feature    14100..14102
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14383..15276
                     /locus_tag="TL08_RS15215"
                     /old_locus_tag="TL08_15390"
     CDS             14383..15276
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012738.5"
                     /locus_tag="TL08_RS15215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_15390"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_069849849.1"
                     /transl_table=11
                     /translation="MAVHTLEQENRRLKWMMLAPALLFIGVMIVFPILYTGYLSLTDAF
                     GAVNADSSFIGLLNFSDALGDLRRFWPAVWRTLVFTVAAVALELTLGLALAMLLRKPFR
                     GMRWVRTIMMVPLLATPVAVGVLWLLILDPTTGIANYLLGLVGIPPQPFLGSVAQSLPT
                     LILIDVWQWTPMMTLLLLAGLSTLPGEPIEAALVDGASAWQRFRHVTLPMLTTAIVTAL
                     VLRSVDALKTFDLIYATKGPGGGSSHEAETLNVYAYGLTFDYQEYGLAASVLVVFTVLI
                     IFIVVALRRRSAKASS"
     gene            15273..16151
                     /locus_tag="TL08_RS15220"
                     /old_locus_tag="TL08_15395"
     CDS             15273..16151
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012738.5"
                     /locus_tag="TL08_RS15220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_15395"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_069849850.1"
                     /transl_table=11
                     /translation="MTAMLPRSESGSIPATEAAAHLRRRKLLTGLRFAAIILVSAVFAT
                     PLIWMVLAAFKTNVQIGNPDDALIFSPTMQNFRNIMGEGIFLPAMVNSAVVGLVSTVLS
                     AIIAVPAAWAIGRFGMHRAGNWVLIARIIPAISLLVPWYYLFARLELVGGYTVLVLSHM
                     FVSVPLITWIMIGFFANLPTELEEAGRVDGLSAFGAFRRISLPLAAPGTATACVLALVF
                     SWNNFIFALILSDESTKTLPVALFNFISYASVDWGGLMAASTLMSVPVILAAVFGQRYL
                     VAGLTAGATKG"
     misc_feature    15531..15533
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16212..17444
                     /gene="manD"
                     /locus_tag="TL08_RS15225"
                     /old_locus_tag="TL08_15400"
     CDS             16212..17444
                     /EC_number="4.2.1.8"
                     /GO_function="GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016052 - carbohydrate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="manD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1268: mandelate racemase/muconate lactonizing enzyme"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012796213.1"
                     /locus_tag="TL08_RS15225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_15400"
                     /product="D-mannonate dehydratase ManD"
                     /protein_id="WP_069849852.1"
                     /transl_table=11
                     /translation="MRIANAEVVVTSPGRNFVTLEIITEDGLRGYGDGTLNGRELAVAS
                     YLTDHVIPLLTGRDAHRIEDTWQYLHRGAYWRRGPVTMAAIAAVDVALWDLKAQVAGLP
                     LYQLLGGASRTGIRAYGHSSGRDLPELFDSVRANLEAGYKSIRIQSAVPGLGTIYGIGQ
                     GVTTGGTGRYDYEPARRHPVPSEEVWDTRAYLRHLPTVFEAVRNEFGPDLPLLHDVHHR
                     LTPIQAAKLGKSLEPYDLFWMEDCTPAENQESLRLVRHHTTTPLAIGEVFNSTVDYQTL
                     IREQLIDYVRSAVTHTGGISPMRKLFDYAAQYQIKSGIHGPTDISPVGMAAGLHLDLAI
                     HNFGIQEFMPHSEETYQVFPRSYTFTDGYLHPGETPGLGVTLDRKAAAAFPYEPAYLPV
                     NRLRDGTVHDW"
     gene            complement(17497..18258)
                     /locus_tag="TL08_RS15230"
                     /old_locus_tag="TL08_15405"
     CDS             complement(17497..18258)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013245.5"
                     /locus_tag="TL08_RS15230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_15405"
                     /product="ABC transporter permease"
                     /protein_id="WP_084643064.1"
                     /transl_table=11
                     /translation="MLKILRDTALVFSHHVRPALRSPIALTSGLAQPILYVALFGPLLS
                     GQILSGTGAESPWLWFIPGVLVMLILFGTAFAGADIQFERETGALERIMATPVSHSALL
                     FGRALRQVATLLVQTVLMICIVLPFGLRVSPLGVLVGLVLIALVGAAVGATSLAVGLLM
                     TDIGSFYTVLGTVTLPLMLTSGVLLPMDSAPGWLLTLSQVNPLSYVVAAERALFVGDFG
                     DPAVLIGLLVAIGGTALAAVFGVAVLRRNAR"
     misc_feature    complement(17932..17934)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18329..19288)
                     /locus_tag="TL08_RS15235"
                     /old_locus_tag="TL08_15410"
     CDS             complement(18329..19288)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062048.1"
                     /locus_tag="TL08_RS15235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_15410"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_069849854.1"
                     /transl_table=11
                     /translation="MIHTRGLTRQFRTKHETVQAVRGLDLDVEPGEIVAFLGPNGAGKS
                     TTLRMLTTLLPPTSGSARVAGCDVTTDPVGVRGRIGYIGQGHGTSEEFRVREELITQGR
                     YQGLRKSDAVRRCDELLNRLSLDAFADRGVGTLSGGQRRRLDIALGLIHDPRLIFLDEP
                     STGLDPQTRASLWEHITGLRETSETTVFLTTHYLEEADLAAERVVVIDHGRIIADGSPN
                     QLKAKVSGDLVRIGMGDAQSAGQAAEIAARLPTAHDTVVDGTATSFRVSHGHEALADLV
                     NALVVAGLRPTEVRVDRPTLDDVYLSLTGRSMREDDAA"
     misc_feature    19859..19872
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.64"
                     /tool="antismash"
     gene            19947..20924
                     /locus_tag="TL08_RS15240"
                     /old_locus_tag="TL08_15415"
     CDS             19947..20924
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="TL08_RS15240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="TL08_15415"
                     /product="hypothetical protein"
                     /protein_id="WP_157421106.1"
                     /transl_table=11
                     /translation="MTSPNPARRRSSRIRLIVGYAAILAILPYFTLKLFWIAGSTAGIT
                     SASSVDPAVIQGGNIVTAAMEIIAALIIIAFTHAWGARIPVFLVLAPTWVGTGLLAPFV
                     ITGPVVAVSVLTGSASVGDDSLAAWVGPLVYVGFGAQAIGIAASFVLYARDRWPHVLTG
                     RVREHPVGPYQPVIAVFVRLATVLLAVVAAVRLPWALGATWGLSPQLIESRGIAERLAD
                     AGTALFAVAAAAGLFVIAFRRPQRQRTALPLALGWIGGGAVFGNGLYPMTLLLAGVAGS
                     GTNATQTGLVPFVDLLQIMTGVMIAVTGAFLLAELNAPTAKQQD"
ORIGIN
        1 cgccgggtgg caaggagccc ggtggagggc gcactgcgtg gatcagagcg cgatgatgac
       61 ggcggtgcag agagtcacga tcaagactgc ggcgagaatg atgaaggcca gtccgatcgg
      121 gtggcgttcc caccacgagg tcagacccgg atataacaga tcgagtttgt tcggtgtgag
      181 agctcgcagc ggcagcgggt agaccggcgc gggcagctgc gccacgagcc ggtccaggtc
      241 tgcccgctcg aaggttccat ccatcaggcg caacagacaa cgtccgcctt catcggcgat
      301 gaagacggtg tggggcgcgg tcctgcccag gagtaccggc ccgtgcacga tgcccttcac
      361 cagcgaacgc ggtatccagc ggatcccgcc gaacatgcct cggtgtccga ggtgtgttcg
      421 ggtgaggacg accaacggcc gaaatcgcga gagggccacc agaccgacga atgcggcgac
      481 caccgccagt cccaccaata tgccgatcca acctgcggtg actgctcccg gcatgatgaa
      541 gatcgaggag atgatcaccg cgagggccac ggtgaagacc cgccgttcgg tggtgggcct
      601 cagggtgagc accggaggat cggttggtga cgacacgggg gcatgctagc cggcgggggt
      661 cgccgcttcg gttggtccgc ccggatcaga cgtcgagtgc ggccaacgaa tcgaggcgat
      721 tccgcaccgg gaatcggatc tcctcgctgt gtcggatcgt cccggaatcg gactcaccca
      781 gatagaaacc ggcggtgaga ctccgctcgt cgacgtcgat gaccgagtgc cagatcgcgc
      841 gccactcggg atccgcggtc ggtgccacct cggcgagcag agcccgcatc gcggtcggcg
      901 acgagacggc tgcctcacct cggcgggtct cgcgatcgag gatccgcatc cgttggtagg
      961 tctcgtgggt gtccgcattg tcgtcgggaa gggcggcggc atccggatac cggtgtaaca
     1021 ggtggttggt cacgcagagc gggccttcgg tcgcccggtt gcgaagtcgg tcgccgcccg
     1081 tcgcgggaac caaccgaagc gcgagtgggc ctcgtcggcc agtgcccggc cgatgtcggt
     1141 ctggctcccc ttggcgacga ggtgccgggt ggtcaggatg tcgttcggcc cgccgcctgc
     1201 cacggcgaca cccgtggata gtcacggtcg tctcggtgcc cccgtccgat actcgtaccc
     1261 ggcggcttgg cgcataccgg atggatgatg cgagtactcg gagccgacca accaggcagg
     1321 tacacgcctg ccacccacgc aatcgtctcc gtgatcgcct tcgtggcggg gctggcaggt
     1381 tggctcggct ccgaatccga cgagtaacag gaaaccggcg tcgacaacga cctgtggtgg
     1441 gtggaccaaa ccgccgaact cgcggagctg gaggccaccg ggcggttccc gctcttgttc
     1501 aacgccaccg aaccaccgga cctgcaggcc acctccgaat tcgggctggc ccggctgctc
     1561 gacggattgg ctccgctctt cgactgacag ccgacggtgc acagagaaga cccccgccag
     1621 gttgttctgg cgggggtctc gggtgttgtt gctcgggtgt ttcttactgg acggtgatgc
     1681 cgcgctcggc cagccacggc tgggggtcga gcttctggcc gccgacgttg acctcgaagt
     1741 gcagatgcgg ccccgtggac tggccacggt taccgatcgt ggcgatctga tccccggcct
     1801 tgacctgctc acccacactc gcggtgaagg tctcgacgtg gccgtaggtg gtgatggtgc
     1861 cgtcgggggc ctggacgcgg acccactggc cgaagccggt agccggcccg gcgttgatca
     1921 ccgtgccatc ggtggccgag accacggggg tgccgatggg gcctgcgatg tcgataccga
     1981 agtggttggt gccccaccgg gcgccgtagc cggaggtgaa ggtgccctcg gcgggcttga
     2041 cgaactccgg acggttggcc tccgcctccg cagccgcctg ctcggcgacc cgggcggaat
     2101 gggcctgcgc ctcacccgcg agggtgtgga actgcaacgt cggagcgacg tcgttgtaca
     2161 gcggggccat cgccgcaccg gcgtcctgct cggccgtgac cccaccatca gcagacgcag
     2221 gggcgggggt ctcggtggca ccggccaaca gcggctgacc gcccagcagg aacgcaccgg
     2281 ccaacaccgc cgacacagcc gacttaccaa ccctggagga acgaacgaac gggttacggg
     2341 tacgcagcgt caaaccaagc tccaatacaa ctcaaggaaa cagaacacgg ggcgcccaaa
     2401 ggaaggccat cgaaaggtcg gcgatccgac ctgccccatg tcccacacga agaagatgaa
     2461 gaggacttga aaggggctcc gacaccggcc gctcgtgggg gccgcgtcgt gatgaccggg
     2521 cgtgacgtac aaatccgaac ctaagcgccg ctcacccaac gccaccaccg gatgtgaccc
     2581 ggaccgccat caggcacgaa ccgacccgtg aaacctcgac gcagcgtcac cactccccgc
     2641 cgaaccgccg cccacaacga ccagacctcg gagcgcctgc gactgatcca cgaactctgg
     2701 aaaccgcccg ccaggcacgg tctcggctgc ggcaggctcg gtcgaccggt tccttgcact
     2761 gcaccgcaaa ccccgcgcgc accggcggcc acagaagctc acaggggtct cggcattgct
     2821 tggccacggc tacggtccgc catcattttc atttaccacc gaagcaacag tgaatgacga
     2881 ctccccgttg gctgcccgag atccgcccca agcagaaggg ctcggcagga catcggccat
     2941 tgaactatcg caacgtcggg ctggcacata gcccgcgcgc tggtgtggct ggtcggagaa
     3001 ggacggcgtg accacggcgt cgttccggct ggcggaggac cgcacgccca ccgacctcga
     3061 cgatgacgcc tatcccctgc cctccggggc gctgatcggt gtggctcacc cggcgatgct
     3121 gcacgacgac ctgacgcggt gggcggcgat cttcgccgac tacgagatca tgcaatcgtt
     3181 tccgcagatc ggcgccgtcg tcccgccgct gaccgacgag gaacgggccg gcccgcggct
     3241 gagccgcttc gaaggcagca ccgtcccgac ccgtgcgctg tcctcgctgc tgcgccgagg
     3301 ttggcatcgc gcggaggagg gcccggtcac gatgttccac cggccggtgg ccgcagatcg
     3361 acgggtggag atctggctcg atccgggtta cacccccggg gcatcggtca atgccaagga
     3421 acagacgctc agggaggtcc gtctcgtctg cgagggaacg ccgttgagtg aggtccgaac
     3481 cgaggccgaa cacgcggtca cccagttcaa cgtgctcgac gaggtggact gccacaagat
     3541 cgtctacgac ctcacccaac tggctcggtg agccatccat cgctgcagga agcgccactc
     3601 atgactgacc atccggttcc cgacgagaac accctcgtgc tacccgaggc gtggtacccg
     3661 cacctcgcac ctcggcgtgg cgggcagcct attccggtcg tcccggtccc gaatgccacg
     3721 gagaaggcgg ctcggctggt ggtctcgggg tgagcaccgt agggccgtcg gcgtaatcgt
     3781 cggttctcga acgcgttgtc cgactgcatt gcgggaaccg atctcgatta gttcatcggc
     3841 tgacccaata gggcgacgcg gttcacccgg acttcgttca tcgcctcttc ttatgcgctc
     3901 ctaccggctt cgacgaaagc ggtcgaggcg ttgtcgtcga acgactcgat tcggccatcg
     3961 ccgcacgtct gatcggcgaa acagctggtc atcgtttgta ggccgaccgc aagactcgcg
     4021 atgaccaccg cttcgccccg acggtgaagt gccggcgatg ccttgcctgc acaacgcagg
     4081 gtgcctaacc tcggaaagcg cttacagaat tcgaccataa ccaccggcac ccattcgacg
     4141 atcagttgcg cacccacgaa tcggtcgtcg tgcgtgccgg agatccgaga acggtctaga
     4201 gcggacaagc gcaagcgctc ggcgtcgatg acgaccgacg agtgtgccaa gaagtgttga
     4261 ccgccaccgg cgtcgaccaa caccaacggc agggatggag tccgacagtg ggcaagcgca
     4321 gatggtgggt tcccgtgctg accgcgatcg cggtcacggg caccctgtcg ataccgccga
     4381 cggcggtggg cagcgattcg acgtcggcgg ccgatccggc cgacgaaccg atcaccgacc
     4441 cgatacccga gaaaccgatc caatcccgcc tcggtctggt cctcgatgaa tacgcgcagc
     4501 ttccggaatc cgaggcgacg ccgccggcca ccgacccccg gctgatccgc cacaatcgga
     4561 tcaacttcgt cggcgaggtc cccgacggct ccggacggga gtacatcccc gacctcaacg
     4621 gtccgctcta tctcctcgac ggcggggacc agcacgtcta tctcgacttc gccgccgagt
     4681 tcgagcactt cttctcgggc cggggcatgg gcagtggttt cgggttcgtc accttccacc
     4741 cagagttcgc cgagaacggc cgtttctaca ccacgcacac cgaggacgag acggcgatcg
     4801 agaacgagga gccgacctac ccgaatcagc cggattcggt cgtgcagagc gtgatcaccg
     4861 agtggaccgc cgacgatccg agcgccgatg tgttcagcgg tagcagccgg gagatcttcc
     4921 gctacggctt ctccacctat atccacgcga tccagcagat cgacttcaac ccgaccgcac
     4981 ggtccggcga cgaggactac ggtttgctct acctcgcggt cggcgacggc ggcatcggcg
     5041 tgcgctcgga tgcgccgcag gaactggaca acccggcggg caagatcctg cgcatcgacc
     5101 cggcgggcac cgacggcccc aacgggaatt acgggatccc gccgagcaac cccttcgtcg
     5161 acacgcccga cgcgctcggc gagatctacg cgctgggcat gcgggatccg caccgcttca
     5221 cctgggatcc ggaacgcgac aacgccatgt acctcggcca catcggtcag cacgcggtcg
     5281 aggcggtcta cgaggtcgag gcgggcgaca acctcggttg gagcgagcgc gagggcgacc
     5341 tgcagtaccg ccgggaggac ggctgctacc tctacccgtt gccggaggac gacgcggagt
     5401 acgactacgt gtaccccgtt gcggcctacg accacgaccc gcccgcgaac tggccgtgtg
     5461 attccgacag cggccacgcc atctccggtg gccaggtgta tcgcggcgag ttggccgagt
     5521 tgcgcggcaa gtacatcttc ggcgatctgg tcgacggcaa ggtgttctac accgaggtcg
     5581 aagagatgcg gcggggccag acacgtgcgc cgctgcacga actgcagctg ttcgacaccg
     5641 agggcacccg gctgcggatg agcgacttcg tcggcgaggg ccgggtcgac ctgcgattcg
     5701 gcatcgactc ggatcgcgag ctctacctgc tggccaagtc caacggcaag atctggcggg
     5761 tcgtcgacac caaacgcggc gccgggtcgg aggtgacccg caaggtcgaa cgcaatctgg
     5821 tcgcccacta cgacttcgag aaccccttcg cggtggacgg ttcctacgag gccgatctcg
     5881 gctcgtccaa caccctgctg agtctgatca acggcgagac ggacatgcgg gtcgccgacg
     5941 gggcgttccc cggcagcaac aacgcgctgc aagtgcagca gatcgcgccg gaggagaacg
     6001 gcaacgacga ctggaaggcc gggatcttcg acgaagacgg cgtggagtcc ttcgaggcgt
     6061 tcaacggcgt cgaggggacg acggtgatgg gctggttcaa gatgaccggc gagaacccga
     6121 gtcccaactc caacaccgag gaccccgacg actattacaa cgccgtcgga ctggcgggca
     6181 tcctgagcgg aagctccgac gggcacgagg tccgggccct gttggagctg atccaggtcg
     6241 acggtgagct gcggttggtg gcgttgggcc gccgcatcga cggcgcggcc tcccagacct
     6301 tcgccgcgca gcaggactgg caggagctgc tcccgcagaa cgaatgggtg cacctggcgg
     6361 cgaccttcga ctacaccacg ggcgagatgg cgctctaccg caacggcgag tcgattccgg
     6421 gcttctacac ccggtccgac gacccatggg aggtcgatgg ttccggcacg tccgccaccg
     6481 atccgaaggg gatcaagatc ggcggcagct tcccgcagaa cgatcgggag gccaatccct
     6541 gcaactgccg gatggattcc ctgatgttcc tggacaccgc tgcggcaccg agcacgatca
     6601 gccagcagta tcaccggttc ctccgccggt gagcggctac cactgatcgc cccggggtcc
     6661 gtccactatg ccggccggac cccggggaca ccgctcgtcg acatgatctt ggccggcacc
     6721 ttcccgtgcg gatacggtga tcgaggcttc cggaacgagc cgagccctct cccgagatga
     6781 acctcgagat gggccttcgg tggaaagcct cgaaccgaga ggacaccgca gtgacggcat
     6841 cgaacaatcg tgcgggacga cacctccttg atcccgagtc cgcggcgctg ctgcggctca
     6901 acggctcgtc gttctaccga ctcctacaga cctgcgcgcc ccaggcgctg ccggagatat
     6961 ccgtccccat cgccccggac gaagcacagc tgccgcacgg caccaccgtg gtggcgatgc
     7021 actaccgcga cggcgtggtg atggccgccg atcggcgtgc cacgatggga aacctcatcg
     7081 cccagcgcga cctccgcaaa ctcgagcccg ccgacagtca ctccggtatc gccttcgcgg
     7141 gcacggtcgg cacggcgatg cgcctggtgt cgctgttcca actcgaactg ctgcactacg
     7201 agaagatcga aggtgtggcg ctcagcttcc cggcgaaggt caaccgggtc tcgaccctga
     7261 tccgaggcaa cctgggcccg gcccgacagg ggctggcggt gatcccgctg ttcgccggat
     7321 gggacgacca cgcgggcgcc gcccgggtct tcaccttcga tatcggcggt tcggcctcgg
     7381 agcaacggga gtacggcggt gcgggctccg gtagcacctt cgctctcggt tcgttgaaga
     7441 agctgtaccg gccggagctg acccggagcg aggcgatccg catcgtgttg acggctctga
     7501 ccgacgcggc cgatgaggac accgccaccg gtggaccgca ggcgcccggg cacctgctgc
     7561 cgctcgtgtc ctgcatcgac gaaagcgggt acgcggcggt tcccaccgag gagatcgccg
     7621 ccgagctcgt ggcggccgac tgaccggtac acccgatcgg ggtgttcgtg atcaccatgc
     7681 ttgacctcaa cctttgatga ggttacaggc tggtgtcatg aacgcaccac cgaggaccga
     7741 ctacggtcac gaagacctgc tcgcgctgct gactctgatg acgggcgacg agaaacacga
     7801 acccagcgcc acctccacgt tggagacgat ctgggtgctc tacgaccgga ttctccgcgt
     7861 cgaccccgcg cgcgtcgacg acccaggtcg tgacaggttc ctgctgtcca agggccacgg
     7921 accgatggcc tactacgcgg tgttggccgc gaaggggttc ctgaccaccg accaactgcg
     7981 tggcttcggc ggcttcgact cgccgctggg ttatcacccg gaccgcaccc tggtgcccgg
     8041 cgtcgagatc ggctccggct ccctcggcca cggcctgggc ttggccgtcg gcaccgcatt
     8101 gggactgcgc gccaccggac acgacgatgc cgccgtggtg gtgctcgtcg gcgatgccga
     8161 actggaggag ggcagcaatc tcgaggccat tcaatacgcc ggacgcgctc ggctcgacag
     8221 gctgacgacc gtggtgatcg acaactcctc cgcctcattg ggctggcccg gcgggatcgc
     8281 ggcccgtttc gcgctcgagg gctggtcgac ggtggaggtc gatggccgcg atctcgacaa
     8341 gctcgaacag gccttcacct cggcgccggg cgaccgcccg cacgccgtca tcgcccacgt
     8401 cgagccgaag gaacgctgat gacgagcacg atggacaacg agacgatcac ttccggggag
     8461 aaccagcgcg accggttcta ccgaatcctt ccccaactgc tcgccgagga cgatcggctg
     8521 gccgccgtgc tcgccgagat cggcgcgtcc tatgtggact cggcggcggc acgggcggtg
     8581 tcggaccggc tgatcaacgt cgggatccgc gagcagctgt tgatcggcgt cgcgggtggt
     8641 ctcgcgctga ccggcctgcg gccgatcgcc cacaccttcg cgccgttctt gatcgagcga
     8701 ccgttcgaac aggtcaaact cgacctcgga caccaggggg tcggcgcggt actggtcagt
     8761 gcgggtggct cctacgactg gccggagggc ggtgagaccc atttcggcta tcgcgacgtc
     8821 gcactgctgg acaccctgca ggactggacg gtgcacgttc cagggcaccc cgacgaggcc
     8881 gaggcactgc tgcgcacctc ggtgcgcggt gacggacggg tctacgtccg gttgggcggg
     8941 gacgcgaaca gcaggccgct ggcggggcgg gacggccgca tgcaggtgtt acggcgtggc
     9001 acacggggga ccgtgatcgc ggtgggcccg atggcggacc gcaccgtcgc cgcgacggag
     9061 ggcctcgacg tcaccgtgct ctacgccgcc acgatcaggc cgttcgacgg cgagacgctg
     9121 cgcgccaccc tcgacgctcc ggaggtcgtg ctggtcgagc cctatctccg gggaacctcg
     9181 atcgccgagg taacccggtc gttggccggg atccggcacc gcgtgtcagg actaggcatc
     9241 ggccccgcgg aagcacggcg ttacggcacc cgagccgagc acgatgtcct gcacggaatc
     9301 gacgaggcgg gactgcgcag acagatcacc gatttcctcg atgcggcagg ctgacggtgc
     9361 tccggtgccg acggggtggg tcgagtgcct cggcgacacc ccggcccggc accggaccgc
     9421 gttcagccgc gactgtccgt cggggtcagc acgatcaccg ccagcgggcg cttgagggtc
     9481 ttggcatagc ggcggtacag gtcccggttg acccggttga cgatgtccca cagcctcgtg
     9541 tgatcggtgt cctcgggcag cacctcgcgg gaggtcacgg cgacgcggcg gcggccgacc
     9601 aggacctcgg ccggtccccc ggcccgcagg ttgtgcagcc accccggcag ccgttccgtg
     9661 ccccagttcg aggccaccac gaggtaatcg gcgccgtccg tgccgtacac cagcgcggag
     9721 gtcctggact tgccgctacg acgtccctgg gtggtcagca acagggtggg ccggatcatg
     9781 agtcgatgac cgacccggcc gccggtgcgt tggtacaccg tctggtgtgc cgaggcgatc
     9841 gaccgaagga gtccttctgc tttcacctac tgaacggtag tcggctgtgg gtcggtacga
     9901 ctcacccgtc cggcccagtt cggtgacgac caggatcgct tccgggtgcc tcgaagcgaa
     9961 tccggtacgc cacatcagga tcgatcggcc acacccgagg tcaggatcgg aaccggcggc
    10021 cgcctcgacc ggacggacgt gaccggtggt cctcgaagag gtcgacgtcg acggcaggcc
    10081 gcgctctatc gccgcgctgt agggcagcag gccaggtcga gacgccgagt ggtcgatggc
    10141 cgccgggtcc ggctcggcgg gtcccgcccg ccaatcgtcc accgaggaca tggggcaagg
    10201 ccaaccgcag caaccgtgcc ttgctcaggg acgcaccctc ccgcagcacc cgcgagccga
    10261 gatggtcgac gacatcgagg tacctacggt ggatctccaa cgccgcgcgg gcgaagggct
    10321 ggaatcgggc aggcaccagg gaggtgatcc tggtcgactc gaggtgcagc tcgcgggccc
    10381 gggacacctg gagtcgtacc agcgcatcca gttccgggcc gacgaccccg cgtcgcaccg
    10441 tcgcccggtc gacctcgcag cgctccatgt cctcggcggg caggtacacg cggccctgcg
    10501 gcaggtcttc cgcgaaatcg cagaagatgt cgatgagctg gtgcacctca ccgatcaacg
    10561 aggcaagccg gtccagctcg gggctcggcg tgcacagcag gcgggcgccc accagagcgg
    10621 ccgtcccgga cacgccacgc aggaagaccc gcaggtcgtc gaaggtggcg aactccgcag
    10681 cgccccggct gtcggcgcgg gtggcctcca ggaatctgat gaacagttcc ggctccaggc
    10741 catggcgccg ggtggtgtcg atcaaggcgc gtcgcagggg atgtcggctc tcgccccggc
    10801 gtagctcgga gaccgcagcc gccgaccagt gccgaaaggc gcgctcgcgc attcgagggt
    10861 cgccgacatc ggccactcgg tcgctggcgg cgaagaaggc caccaccgca tgcacctggg
    10921 ggcggatagc gggcggcagc agcaaccggg ccgcgaggta ggtgggccgg tgcgtggcat
    10981 gcaaccgtcg acacagcgca taggagtccc ggagaagcgg gtcgagtctt ctcgtcggtg
    11041 ccgcatgcaa cgccatggtc gtctgacctc gccggggtgt cggtgctgcg gggagcgggc
    11101 ttctcgcgaa ggcgacgaga ggacgatccg ccatggtcga ccttccgccg atttcgcggc
    11161 agaccgacca ctcacagcac gatgctgcgg gccatcgatc catcatcgcc gcccgcaccg
    11221 aggaatccac cgatccgggc tcgataactg cggggatcac caccggagcc cgaatagccg
    11281 aggactccgg ataccgtgcc tgcactggcg cgtgcacctc ggcctcttgc ggccgagaga
    11341 cccagcgaaa gagcttgcac gatacggcga acgacccggc tcaaggctac tgaggcgggc
    11401 agttccctgc catcacacga tcgatcacca tccgagctgg ttgccgccga cggcgccgac
    11461 ctgcctgcga taaccggtgg actccggaca tcggcggcgg acagagtgaa cagatgcaca
    11521 cgaccaccga gttcatcgag acgctgcatc gcgaggggga acgcttcgcg gacaccgcag
    11581 agcacgtcga tctcaccgcg cccgtgcccg gctgtcctgc ctggtcggtg cgtgacctcg
    11641 tcttgcatct gggtgcggtc catcggtggg ctaccggcta tgtggtcgag ggcaggacac
    11701 agcccgagcc cattgccgag gctccggcac tggaggacac cgaactggcc ccgtggttac
    11761 gcgacggcca tgctcgcctg gtggcggccc tgaccgaggc gcccgccgag ctggactgct
    11821 ggaccttcct acccacgggg gtggagccac tggagttctg ggcgcgcagg caggcttacg
    11881 agacctcggt gcaccgggtc gacatcgagg ccgcaagcgg tctcgcgctg tccccgatgg
    11941 cccctgagtt cgcctcgggc ggcatcgacg agttcctccg tggattccag gcgcgcccga
    12001 gtagcccggt gcgtaccgag acaccgaaga cgctgcggat cctgcccacc gacgtgcccg
    12061 ctgcgggttg gacggtgtcg ttgtcggcgg acaagccgcc gcgcaccgag cggaccaggg
    12121 atgggcagcc cgccgactgc acctacaccg gccctgcgat ggcgctgtac ctggtgttgt
    12181 acaaccggct tccgatcgac gccgtgcagt gcggcggtga cgtatcgctg gcgcaacgct
    12241 ggcgggatct caccagtagc tgatcggctt ccagcacgcg gctgcgtcag cacggatagg
    12301 cgcgatcgca ccctccggac gcggtcggaa ctcggcgtat atcggccgcg tccggcgagg
    12361 cgagagcgtg cttgctggac tcgccgcacc gagccgcacg gcccactgga tagcggtgga
    12421 tcggggcgac ggtgctcgac caggcaggcg gcacgcctgt ccggccgtct gcggctcgcg
    12481 gcggcatacc gaagccgatc aaggagatgc gagcacgccg gggtcggcat tcgcgtcgtc
    12541 gaatcctctt cgacgccgaa cccttccgcc ccgggggacg gatgacgtat cttcctgaaa
    12601 cctgatcgcc tgttcacata tgtaggcagt gtcgccacct atgagaagtg cgaggtccca
    12661 tgttcgacat cagtctcgcc tcggtcacca ctcccctgcg ccgatcaccc cgccggtccg
    12721 tacgccgtcc agaacgccct gcaccgatgt gatcgcgccc cagcggtcga gccggtcgcc
    12781 gcgctagagc gatccggctc ccgtcgaggg ccccggaacg tctcgcggcg accccgccac
    12841 accggagcac tcgagaaccg agtccgtccg cggctcggca cccgtctcct cgatcgggcg
    12901 acggtcgact tcggccgggc cacgacgcgg cgacccacga acccgtacgc ggttccgagg
    12961 caccccttct cgggacgacg caccggtttc catcgacgtc accactggtg cgcagcacgt
    13021 tctcggcgtg aagcgcaccg agacctcgcc agcgccgcct gatccgcggt gaacgggaag
    13081 tagaggcacc gatgctgaag cgacgcgacg ccctgcgaat actgggtctg agcgcggtgt
    13141 tgggttcggg ctccctgggg ctcgcaggct gtggcagctc cggcgacggg gcgaacgggc
    13201 cgctgcgggt ggccctggtc aaccacgtct ggaccagcgc gatccgcgag cgcatcgccg
    13261 agttcgagga cctgaccggg cgacgggtcc tcgtctcgac gatgacctcc gatcagctgt
    13321 cgagcaccta caacgtcaag ctcaacgcca gcgcgcccga cctcgacgtg atgatgtacc
    13381 gcccgttgca ggagcagttg ttgttcgccc gcaacggttg gctgaccgag ttcaacgatc
    13441 tcgtcgccga cgacagcgag tacgactggg ccgacgtcca agacggcccg aaggaccggg
    13501 tgacgatcga cggccggatc ttcggcgtac cgatcatcac cgaacgaccg acgctgtact
    13561 accggcgcga cctggtggac gcgccgccga ccacgctgga ggagatgtac gagacggccc
    13621 gcaggctgca ctcgccggat accggcttgc acggcttcac cggtcgaggc caacgcgcgg
    13681 gtgcggtcag catgttctcc agctatctct attcccacgg cgcggacttc atcgtcgacg
    13741 gtcggtccgg ggtcggctcg ccggaggcac ttgccgccta cgagtactac ggcaggttgc
    13801 tgcgggaggc gggtccgatc ggtgcgacca acatgacgtt ggagcagatc accccgatct
    13861 tcgcgcaggg caaggcggtc ttcgccatcg acgccgacgc cgtctaccag aacttcatcg
    13921 acccggcgac ctcgacggtc ggcgaccgca ccgggttcgc cgccttcccg gcgggcccgg
    13981 cggggtcccg ccccttcaac atcgcgtcct gggggttgac catcaacgcg ttctccgaac
    14041 ggcgcgacat cgcctgggag ttcatccgct gggctagcgg tcccgagatg accctgcggt
    14101 tacagaacga gggcgtgccc agcgcccgga cgtcggcgtg ggcggacgag gcgagtctga
    14161 ccgcgttccc gccggatctg gccgagtcga tggccgccgg gatcgagacc ggcgtcggcg
    14221 ccgatcgccc ggatgtcgtc caggtcggtc gggcccgcga catcgtgggg cggccgatcg
    14281 tcgcaagcat cctcggtgac gatgtcgccg cctcggcccg cgacgcctcc gaggaattcg
    14341 acgagttcct ggtccgcgac gctcgacaaa ggcagctctg acatggcagt acacacactg
    14401 gagcaggaga accgtcgtct caagtggatg atgctcgcgc ctgcgttgct gttcatcggc
    14461 gtgatgatcg tcttcccgat cctctacacc ggttatctga gtctgaccga cgccttcggg
    14521 gcggtgaacg cggacagctc gttcatcggg ctgttgaact tcagcgacgc cctcggtgat
    14581 ctgcggcgat tctggcccgc ggtgtggcgg accctcgtct tcaccgtggc cgccgtcgcg
    14641 ctcgaactca ccctcgggct ggccctggcg atgttgttgc gcaagccgtt ccgggggatg
    14701 cgctgggtgc ggaccatcat gatggtgccg ctgctggcga cgccggtcgc ggtgggcgtg
    14761 ttgtggctgc tcatcctcga cccgaccacc ggcatcgcca attacctgct cgggttggtc
    14821 ggcatcccgc cgcagccgtt cctcggttcc gtagcgcaat cgctgcccac gctgatcctg
    14881 atcgacgtgt ggcagtggac cccgatgatg accctgctgt tgttggccgg gctcagcacg
    14941 ctgccgggcg agccgatcga ggcggcgttg gtcgacgggg cgtcggcctg gcaacgattc
    15001 cggcacgtca cgctgccgat gctgaccacg gcgatcgtca ccgcgttggt cctgcgcagt
    15061 gtggacgcgt tgaagacctt cgacctgatc tacgccacca agggcccggg tggtggttcc
    15121 agccacgagg ccgagacgct caacgtctac gcctacggtc tgaccttcga ctaccaggag
    15181 tacggcctgg ccgcctcggt gttggtcgtg ttcaccgtgc tgatcatctt catcgtcgtc
    15241 gcgcttcggc gccgttccgc gaaggcatcc tcatgaccgc catgctgccg cgatccgagt
    15301 cagggtccat tcccgccacc gaggccgccg cgcatctgcg ccgccgcaag ctgctcaccg
    15361 gcctccgctt cgcggcgatc atcctggtca gcgcggtgtt cgccaccccg ttgatctgga
    15421 tggtgctcgc cgcattcaag acgaacgtgc agatcggcaa ccccgacgat gcgctgatct
    15481 tcagcccgac gatgcagaac ttccgcaaca tcatgggcga gggcatcttc ttacccgcca
    15541 tggtgaactc cgccgtggtc ggcctggtct cgacggtgct ctcggccatc atcgcggtac
    15601 ccgcagcgtg ggccatcggt cggttcggca tgcaccgggc cgggaactgg gtgttgatcg
    15661 cccgcatcat ccccgccatc tcgctcctgg tgccctggta ctacctgttc gcccggctgg
    15721 aactcgtcgg cggctacacc gttctggtgc tcagccacat gttcgtctcg gtgcccttga
    15781 tcacctggat catgatcggc ttcttcgcca atctgccgac cgagctggag gaggccggcc
    15841 gcgtcgacgg gctgtccgcc ttcggcgcct tccgtcggat ctccctgccc ctggccgcgc
    15901 cggggaccgc gacggcatgc gtgttggcgt tggtgttcag ctggaacaac ttcatcttcg
    15961 ccctgatcct gtccgacgag tcgaccaaga ccctgccggt ggcgctgttc aacttcatct
    16021 cctacgccag tgtggactgg ggcggtctga tggcggcctc gacgctgatg agcgtgccgg
    16081 tcatcctcgc cgccgtcttc ggccagcgtt atctggtggc cgggctgacc gccggagcca
    16141 ccaagggctg agcccgcacg ccgggcgacg ggcccgggct ggaacaaccg gtctcccacg
    16201 aaaggaagca catgcggatc gccaacgccg aggtcgtcgt cacgagcccc ggtcgcaact
    16261 tcgtcaccct cgagatcatc accgaggacg ggttgcgcgg gtacggcgac gggacgctca
    16321 acgggcggga gctcgccgtg gcgagctacc tgaccgacca cgtcatcccg ctgttgaccg
    16381 gtcgggacgc gcatcggatc gaggacacct ggcagtacct gcatcgcggc gcctactggc
    16441 ggcgcggtcc cgtgaccatg gcggcgatcg ccgccgtcga cgtcgcgttg tgggatctca
    16501 aggctcaggt cgcggggctg ccgctctacc agcttctcgg tggcgccagt cgcaccggga
    16561 tccgtgccta cggtcattcc agcggccggg atctaccgga gctgttcgat tcggttcgcg
    16621 cgaatctcga agcgggctac aagtcgatcc ggatccagtc cgccgtcccg gggctgggca
    16681 ccatctacgg catcggtcag ggcgtcacca cgggcgggac cggtcgctac gactacgagc
    16741 ctgcgcgcag gcatcccgtt ccgtccgagg aggtctggga cacccgggcg tatctgcggc
    16801 acctgccgac ggtcttcgag gcggtgcgca acgagttcgg tccggatctg cccctcctgc
    16861 acgacgtgca ccatcggttg accccgatcc aggcggcgaa gctgggcaag tccctggagc
    16921 cctacgacct gttctggatg gaggactgca ctcccgccga gaatcaggag tcgctacggc
    16981 tggtccggca ccacaccacc actcccctgg cgatcggcga ggtgttcaac tccacggtcg
    17041 actatcagac cttgatccgc gaacaactta tcgactacgt ccgttcggcg gtcacccata
    17101 ccggcggcat ctccccgatg cgcaaactct tcgactacgc agcgcagtat cagatcaagt
    17161 ccggcatcca cgggccgacc gacatctctc cggtggggat ggccgcaggc ctgcacctgg
    17221 atctggcgat tcacaacttc ggcatccagg agttcatgcc gcacagcgag gagacgtatc
    17281 aggtcttccc gcgctcgtac accttcaccg acggctacct gcatcccggg gagacgccgg
    17341 ggctcggagt cacgctggat cgcaaggcgg ctgcggcctt cccctatgaa cccgcctatc
    17401 ttccggtgaa ccgactccgg gacgggaccg tgcacgactg gtgaggccta ggtccctggc
    17461 aggccggtct caggccggcc tgccaggacc gactgctcag cgagcgttcc gccgcagcac
    17521 cgccacgccg aacaccgcgg ccaatgccgt accaccgatt gcgacgagca gtccgatcag
    17581 cacggcgggg tcgccgaagt cgcccacgaa cagggctcgt tcggcggcca cgacgtagct
    17641 cagcgggttg acctgcgaga gagtcagcag ccagccgggc gcggagtcca tcggcagcag
    17701 cacccccgac gtcaacatca gcggcagcgt gaccgtcccc aacacggtgt agaaggaacc
    17761 gatgtcggtc atcaacaatc ccaccgcgag cgaggtggca ccgacggccg cgccgaccag
    17821 ggcgatcagc accaagccga cgagcactcc gagcggcgag acccgcaggc cgaacggcag
    17881 cacgatgcag atcatcagga cggtctgcac cagcagggtc gccacctgcc gtaacgcccg
    17941 accgaacaac agggccgagt ggctgaccgg ggtggccatg atgcgttcga gcgcaccggt
    18001 ctcccgctcg aactggatgt cggcgcccgc gaacgcggtc ccgaacagga tcaacatgac
    18061 gagcacgccg gggatgaacc acagccaggg cgattccgcg cccgtgccgc tgaggatctg
    18121 accggacagc agggggccga acaacgccac gtacaggatg ggctgggcca acccactggt
    18181 caacgcgatc gggctgcgta gcgcgggccg gacgtgatgg gagaagacga gcgcggtgtc
    18241 acgaaggatt ttcagcatcg gttctcctgc tctcgggcgg ttcgggggtc ggggtcgaga
    18301 cgggcgggtt cggtgacggt ctgctcggtc atgccgcgtc gtcctcacgc atgctccggc
    18361 cggtgagcga gagatagacg tcgtcgaggg tcggccgatc gacgcgaacc tccgtcggcc
    18421 ggagtccggc gacgaccaag gcgttgacca ggtcggcgag cgcctcgtgg ccgtgtgaga
    18481 cccggaaact ggttgccgtg ccgtccacga ccgtgtcgtg cgcggtgggc agtcgggccg
    18541 cgatctccgc cgcctggccc gctgattgcg catcgcccat gccgatgcgg accagatccc
    18601 ccgacacctt ggccttgagt tggttcggcg agccatcggc gatgatccgg ccgtggtcga
    18661 tcaccaccac gcgctcggcg gcgagatcgg cttcctcgag gtagtgggtg gtcaggaaca
    18721 ccgtggtctc ggaagtctcc cgcagcccgg tgatgtgctc ccacaggctg gccctggtct
    18781 gcgggtccag tccggtggag ggctcgtcca ggaagatcaa ccgggggtcg tggatcaagc
    18841 cgagcgcgat gtcgagccgc cgccgttggc cgcccgagag cgtgccgact cctcgatcgg
    18901 cgaaggcgtc caaggacaga cggttcaaca actcatcgca ccgccgcacc gcgtcgctct
    18961 ttcgaaggcc ctggtaccgc ccctgggtga tcagctcctc gcggacccgg aactcctcgc
    19021 tggtgccgtg gccctgaccg atgtaaccga ttcggcctcg gacaccgacg gggtcggtcg
    19081 tcacgtcgca gcccgccacg cgggcgcttc ccgacgtcgg cggaagcaag gtggtgagca
    19141 tccgcaaggt cgtgctcttg cccgccccgt tcggcccgag aaaggcgacg atctcgcccg
    19201 gctcgacgtc gagatcgagg ccacggaccg cctgaacggt ctcgtgcttg gtacggaact
    19261 gcctggtcaa acctcgggtg tggatcacgc ggcctcctgc tcaaatttga gtccccgcgc
    19321 agggcgggac caccgggtcg gttcaaaggt cggtagaggg cgatctctcc acccgccgtc
    19381 ggactcaaac ttgagtcact ggtcggacgc cgggggccgg actcgatcgg ggcaacaacc
    19441 tagcccaccg ccgccgcctt gcacaaattt gagtagacca tcgatgtata cgtcgcactc
    19501 gtcagccgta ggcggccgat accgcatggg gcgccccgca caaagcgctt gacgacaacg
    19561 tcgatgccgc ctgcccaccc gcgaatagac caacttaccc aggcggcaaa taaagcgatt
    19621 cccccacatc gcgaccgtcg gacggaatcg cgtcacgatt cgtattagcc cgtcgacacc
    19681 gagcggaccc gtcgaggcgc ctcgcgcgca ataccgcaca acccgaccgg gactgagccg
    19741 atcacggact atcgagaaga tcgtcacacc ctatccggca gcacgggatt cgacaactag
    19801 gcgatctcgg catcgggtac agtcccagcc cagccgcaac ctgtggcaac agtcgccgat
    19861 cacgctgcgc gacgccatct cgacaggaaa gggccggtgg gtctcccatg agctccacgc
    19921 cgacggaaac gagggctgaa acgatcatga cgagcccgaa tccggcccgc cgacgaagct
    19981 ctcgaattcg attgatcgtc ggatacgcgg caattctcgc cattcttccg tacttcaccc
    20041 tcaaactatt ctggatagcc ggttccaccg ccggtatcac cagcgcctcc tcggtggatc
    20101 ccgcagtcat ccagggtggg aatatcgtca cggcggcaat ggagatcatc gccgcgttga
    20161 tcatcatcgc gttcacccat gcctggggcg cgcggatacc ggtattcctg gtcctcgcgc
    20221 cgacctgggt gggaacgggc ctgctggcgc cgttcgtcat caccggcccg gtcgtcgcgg
    20281 tatcggtcct gaccggatcc gcgagcgtgg gtgacgactc cctcgcggcc tgggtcggcc
    20341 cgctggtcta cgtcggattc ggcgcccagg cgatcggcat cgccgcctcg ttcgtgctct
    20401 acgcgcgcga ccggtggccg cacgtactca ccggacgcgt gcgggaacac ccggtgggcc
    20461 cctatcaacc ggtgatcgcc gtgttcgtcc ggctggccac cgtgttgctc gccgtggtgg
    20521 ccgcagtgcg actgccctgg gccttggggg cgacgtgggg gttgtcgcca cagctgatcg
    20581 agagccgagg gatcgcggag cggctcgcgg acgcgggcac cgcgttgttc gcggtcgcgg
    20641 cggcggcagg tctgttcgtc atcgccttcc ggcgtccgca gcgacagcga accgcgctac
    20701 cgctggccct cggttggatc ggcggcggcg ccgtcttcgg taacggcttg tatccgatga
    20761 cgctgctgct ggcaggcgtc gcgggctccg gcacgaacgc gacccagacg gggttggtgc
    20821 ccttcgtcga tctgctccag atcatgaccg gggtgatgat cgcggtgacc ggcgccttcc
    20881 tgctcgccga attgaacgca ccgaccgcca agcagcagga ctgacgccga acgcggcatc
    20941 cgcgacctcg cccggccgcc accgccccac cggggcgacc ggctacgccg ggcgaggttc
    21001 gtcgtccgcc aggcgatagt cgccacgctc aagccgctga agaagcaatc tggtcc
//
