LOCUS       NZ_CP014859            21275 bp    DNA     circular CON 20-NOV-2024
DEFINITION  Actinoalloteichus hymeniacidonis strain HPA177 chromosome, complete
            genome.
ACCESSION   NZ_CP014859
VERSION     NZ_CP014859.1
KEYWORDS    RefSeq.
SOURCE      Actinoalloteichus hymeniacidonis
  ORGANISM  Actinoalloteichus hymeniacidonis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Actinoalloteichus.
REFERENCE   1  (bases 1 to 6306386)
  AUTHORS   Schaffert,L., Albersmeier,A., Winkler,A., Kalinowski,J.,
            Zotchev,S.B. and Ruckert,C.
  TITLE     Complete genome sequence of the actinomycete Actinoalloteichus
            hymeniacidonis type strain HPA 177T isolated from a marine sponge
  JOURNAL   Stand Genomic Sci 11, 91 (2016)
   PUBMED   28031775
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6306386)
  AUTHORS   Schaffert,L., Albersmeier,A., Winkler,A., Kalinowski,J., Zotchev,S.
            and Ruckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAR-2016) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Coverage                   :: 159x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001747425.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 01:17:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,434
            CDSs (total)                      :: 5,374
            Genes (coding)                    :: 5,337
            CDSs (with protein)               :: 5,337
            Genes (RNA)                       :: 60
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 37
            CDSs (without protein)            :: 37
            Pseudo Genes (ambiguous residues) :: 0 of 37
            Pseudo Genes (frameshifted)       :: 3 of 37
            Pseudo Genes (incomplete)         :: 34 of 37
            Pseudo Genes (internal stop)      :: 1 of 37
            Pseudo Genes (multiple problems)  :: 1 of 37
            CRISPR Arrays                     :: 13
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:46:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2556615
            Orig. end                         :: 2577890
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP014859.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21275
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="11"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21275
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21275
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11275](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11275)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(285..300)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.38"
                     /tool="antismash"
     gene            532..1257
                     /locus_tag="TL08_RS11700"
                     /old_locus_tag="TL08_11800"
     CDS             532..1257
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075911.1"
                     /locus_tag="TL08_RS11700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11800"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_236750949.1"
                     /transl_table=11
                     /translation="MARLLLENGPATAAVIAEELGLGQAAVRRHLDALIADGQASTRQA
                     PKGPRGRGRPARLYLLTEAGRARFGHAYDDLAVSALRFLAEHVGEHAVTAFARQRVADL
                     VVRHRAVVAAAEPEARAEVLAEALTSEGYASSTRRVRSGEQLCQHHCPVAHVAAEFPQL
                     CEAETALFAELLGTHVQRLATIARGDAACTTHVPHAERAPEHTDIEQSESPDCSSTSLV
                     PATATPVQTAPNPDGGEPA"
     gene            1254..2723
                     /gene="sufB"
                     /locus_tag="TL08_RS11705"
                     /old_locus_tag="TL08_11805"
     CDS             1254..2723
                     /GO_process="GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sufB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006236603.1"
                     /locus_tag="TL08_RS11705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11805"
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="WP_069848835.1"
                     /transl_table=11
                     /translation="MTAAAEQRTPTTASTTQGQQPLTQEETLATLGNYEYGWADSDAAG
                     TSARRGLNEDVVRDISGKKSEPDWMLQTRLKGLSLFERKPMPNWGADLSGINFDAIKYF
                     VRSTEKQATSWEDLPEDIKNTYDRLGIPEAEKQRLVAGVAAQYESEVVYHKIREDLEEQ
                     GVIFLDTDTGLKEHPELFQEYFGSVIPAGDNKFSALNAAVWSGGSFIYVPKGVQVDIPL
                     QAYFRINTENMGQFERTLIIVDEGAYVHYVEGCTAPIYSSDSLHSAVVEIIVKKGGRCR
                     YTTIQNWSNNVYNLVTKRAKAEEGATMEWIDGNIGSKVTMKYPSVYLMGEHAKGEVLSI
                     AFAGEGQHQDTGAKMTHLAPHTSSTIVSKSVARGGGRASYRGLVRVNKGSHHAKSTVKC
                     DALLVDTISRSDTYPYVDVREDDVAMGHEATVSKVSDDQLFYLMSRGLTEDEAMAMVVR
                     GFVEPIARELPMEYALELNRLIELQMEGAVG"
     gene            2725..3918
                     /gene="sufD"
                     /locus_tag="TL08_RS11710"
                     /old_locus_tag="TL08_11810"
     CDS             2725..3918
                     /GO_process="GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sufD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007024596.1"
                     /locus_tag="TL08_RS11710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11810"
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="WP_084642902.1"
                     /transl_table=11
                     /translation="MATPTHTSDVTPGVAGKAHSHGGPVIPQSSRGERFTSYDVAAFEV
                     PGGREEDWRFTPLRRLAGLHEAAKTVDGSLTVEVTAEAPVTVETVDRSDARIGQGGVPA
                     DRVAAAAWSGFTEATVVTIPGDTRPDPISVVVTGPGADKSAYGHLHLRAEAFAEATVVL
                     DYRGSGAVADNVEIVAGDSARLTVITLHDWATDAVHVGAQHASVGRDATLRHFAVTLGG
                     DLVRISSTVNYRDRGGDAELLGLYFADAGQHLEHRMLVDHSVPNCRSNVVYKGALQGEG
                     AHTVWIGDVLIQAAAEATETFELNRNLILTDGARADSVPNLEIETGEIQGAGHASATGR
                     FDDEQLFYLQARGIPVEVARRLVVRGFFGEILQKIAVPEVRERLEAAIEAELAAVGT"
     gene            3915..4250
                     /locus_tag="TL08_RS11715"
                     /old_locus_tag="TL08_11815"
     CDS             3915..4250
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686141.1"
                     /locus_tag="TL08_RS11715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11815"
                     /product="non-heme iron oxygenase ferredoxin subunit"
                     /protein_id="WP_236750718.1"
                     /transl_table=11
                     /translation="MTMTPVCEVDELPEGKPVRHDVDGVSVVLVRDAHGVHALHDVCSH
                     AEVALSEGDLVTKGGKLMLECWLHGSCFDLRTGAPTGLPATDPVAVFATEISQGWVRVD
                     PARRIAG"
     gene            4324..5094
                     /gene="sufC"
                     /locus_tag="TL08_RS11720"
                     /old_locus_tag="TL08_11820"
     CDS             4324..5094
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sufC"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016333168.1"
                     /locus_tag="TL08_RS11720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11820"
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="WP_069848839.1"
                     /transl_table=11
                     /translation="MATLEIKDLHVSVSTDDAPKEILKGVDLTVRGGETHAIMGPNGSG
                     KSTLAYAIAGHPKYEVTSGSVLLDGEEVLEMTVDERARAGLFLAMQYPVEVPGVSMSNF
                     LRSAATAVRGEAPKIRHWVKEVKQAMTDLDIEPSFAERSVNEGFSGGEKKRHEILQLDL
                     LKPKFAVLDETDSGLDVDALRVVSDGVNRYTAGGDKGVLLITHYTRILKHIAPDHVHVF
                     AGGRIVESGGAELADQLERDGYVRFTGNKETAAV"
     gene            5202..6512
                     /locus_tag="TL08_RS11725"
                     /old_locus_tag="TL08_11825"
     CDS             5202..6512
                     /EC_number="2.8.1.7"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_5 (30-411). E-value: 3.5e-138.
                     Score: 452.5. Matches aSDomain:
                     nrpspksdomains_TL08_RS11725_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007029704.1"
                     /locus_tag="TL08_RS11725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11825"
                     /product="cysteine desulfurase"
                     /protein_id="WP_069848841.1"
                     /sec_met_domain="Aminotran_5 (E-value: 8.4e-137, bitscore:
                     454.3, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.2e-08,
                     bitscore: 32.9, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.2e-05, bitscore:
                     22.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATTATPLDIASIKADFPILARTVRDGKPLIYLDSGATAQRPRQV
                     LDAERAFLETSNAAVHRGAHQLMEEATDAYESARARIAAFIGVDDDEVVFTKNATEGVN
                     LVAYAMGNAATSGPEAARFRLGPGDEIVVTEMEHHANLVPWQQLCARTGATLKWFGVTD
                     EGRLDLSDADSVVTEHTKVVAFTHQSNVLGTVNPVSELVALAKRVGALTVLDACQSVPH
                     AAIDLHALDVDFAVFSGHKMLGPSGVGVLYGRRELLAALPPFLTGGSMIEIVRMESSSF
                     AAPPQRFEAGVPMTSQAVALGAAVDYLRVVGMDRIADHEKTLVEATLAGLAEVPGVRIV
                     GPSDTVARGGAVSFVIDDIHPHDAGQVLDSLGIAVRVGHHCAWPLHRRLGIQATMRASF
                     YLYNDLSDVEALVAGVRESRRFFGVDSDGATSAAGVA"
     aSDomain        5292..6434
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_TL08_RS11725_Aminotran_5.1"
                     /evalue="3.50E-138"
                     /label="TL08_RS11725_Aminotran_5.1"
                     /locus_tag="TL08_RS11725"
                     /protein_end="411"
                     /protein_start="30"
                     /score="452.5"
                     /tool="antismash"
                     /translation="IYLDSGATAQRPRQVLDAERAFLETSNAAVHRGAHQLMEEATDAY
                     ESARARIAAFIGVDDDEVVFTKNATEGVNLVAYAMGNAATSGPEAARFRLGPGDEIVVT
                     EMEHHANLVPWQQLCARTGATLKWFGVTDEGRLDLSDADSVVTEHTKVVAFTHQSNVLG
                     TVNPVSELVALAKRVGALTVLDACQSVPHAAIDLHALDVDFAVFSGHKMLGPSGVGVLY
                     GRRELLAALPPFLTGGSMIEIVRMESSSFAAPPQRFEAGVPMTSQAVALGAAVDYLRVV
                     GMDRIADHEKTLVEATLAGLAEVPGVRIVGPSDTVARGGAVSFVIDDIHPHDAGQVLDS
                     LGIAVRVGHHCAWPLHRRLGIQATMRASFYLYNDLSDVEAL"
     gene            6514..6975
                     /gene="sufU"
                     /locus_tag="TL08_RS11730"
                     /old_locus_tag="TL08_11830"
     CDS             6514..6975
                     /GO_function="GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /GO_process="GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sufU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005152220.1"
                     /locus_tag="TL08_RS11730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11830"
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="WP_069848843.1"
                     /transl_table=11
                     /translation="MQLDQMYQEIILDHYKHPHGHGLREPFDAESHQVNPMCGDEVTLR
                     VALSGHDSAATVVDVSYESQGCSISQASTSVLTDLVVGRPLPEVMTVSEAFLELMQGRG
                     KVEPDEDVLGDGIAFAGVARYPARVKCALLGWMAFKDAVSRVVDEVRTV"
     gene            6972..7391
                     /locus_tag="TL08_RS11735"
                     /old_locus_tag="TL08_11835"
     CDS             6972..7391
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686145.1"
                     /locus_tag="TL08_RS11735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11835"
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="WP_084642904.1"
                     /transl_table=11
                     /translation="MTSVADQNSDPGAEQVQRGVEGLPEPPAPRADKPEIEDIEEAMRD
                     VVDPELGINVVDLGLVYGVTVDDSNIATIDMTLTSAACPLTDVIEDQTRSALTGGPDGG
                     LVSDIRINWVWMPPWGPEKITDDGRDQLRALGFTV"
     gene            complement(7476..7691)
                     /locus_tag="TL08_RS11740"
                     /old_locus_tag="TL08_11840"
     CDS             complement(7476..7691)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010695763.1"
                     /locus_tag="TL08_RS11740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11840"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_069848845.1"
                     /transl_table=11
                     /translation="MDTSTRVSGWRKSSRSANNGTCVELAWVGDAQAIRDSKAPGAGAL
                     ALTPSQSADFFTSVKAGRFDRPRRGR"
     gene            complement(7821..8060)
                     /locus_tag="TL08_RS11745"
                     /old_locus_tag="TL08_11845"
     CDS             complement(7821..8060)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009946949.1"
                     /locus_tag="TL08_RS11745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11845"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_236750719.1"
                     /transl_table=11
                     /translation="MRTTSNPTDSRVNPTYWRKSSRSADTGGNCVEVGLDNNEIQAIRD
                     SKAPEAGALSLTPTQSGDFFAAVKAGRFDRPRPV"
     gene            complement(8208..10004)
                     /locus_tag="TL08_RS11750"
                     /old_locus_tag="TL08_11850"
     CDS             complement(8208..10004)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010310674.1"
                     /locus_tag="TL08_RS11750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11850"
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_236750720.1"
                     /transl_table=11
                     /translation="MTEQTDKDATSVSSSISDRGEHGQVTAPPQNVRFAFQPLVNLATG
                     GIVALEAVPRPHGGEMRELFRQAVQARKLTELDVELAMAAASEAAAGGTRLPLHINVLA
                     GTIAYDIERFELLDAVLDEAGRPPHQVTLEVGPPFYRLDHEALLNGLGVLHERGYRLGL
                     DGLGEGDAPLRLVASGLINLLKLDQTLATRAHAEPATLAFIESMVTFADHSGMQLAVHG
                     VDTEEQLTALRAAGVGLVQGDLIAAPSRRPMSQVAVSSVLSELSQVQAPRIAARSAGPR
                     VTDFLQPAVPLPTTATADEVRVVFADHPDSTSVVLLDRTGRPHRLVDRNRFLLAVTGPY
                     GHALHARREALRLAEEPKLVGTHNTVVEALDLVADSGPDQMYVDLVVVDEAGRCLGVVR
                     AGDLFRGVAEMKVEQAATLNPLTRLPGTDSVAMEIDQRLADGEAFTVSWLDIDGFKGVN
                     DTVGFAAGDELIRSLGRHLTDLAAGMPGVVVGHVGGDDFLVVCDLDQLMPLGAELLDVE
                     REAEGRPVTVSLASLVCAPGTVPSHHDASRRLSPLKSRAKALLGTSWVVGRSTSDQVDE
                     LRGTPPQSPSQSQMPPRRRATG"
     misc_feature    complement(8952..8954)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9552..9554)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..11275)
                     /locus_tag="TL08_RS11755"
                     /old_locus_tag="TL08_11855"
     CDS             complement(10001..11275)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017634.5"
                     /locus_tag="TL08_RS11755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11855"
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_084642906.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 1.2e-55, bitscore:
                     187.4, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVDIVIAGAGPAGRALGAACADLGLSVTLIDPAPQRPWRATYGLW
                     LDELPGLPDRVIATCAETVLVVTDSGQRRLTDRSYCVLDNAALRAELARPDIVQHTGRV
                     RAVEHSGSGCTVLLADGRSIEAGLFVDASGTGRWRRGSSPAVGHCSEAAAGTRLGSAGT
                     DRCGARRQSAAQTAFGVVLPSTAARRYVAPGEAILMDWRPVEQVGRTPSFCYAVPLGDD
                     EVLIEETCLAGRPALSFGELRNRLSRRMAGHGVDLSGVRRRERVRIDLDRPAATTARTM
                     SFGAAAGLVHPASGYGLATALRLVPAMATALAAGVRSGPSAVTRAARHVLWPPKARMVH
                     ALRRYGLEVLLTLDRAESSEFFTSFFRIPTDVRTSYLSDREDVLGTAKAMVAVLAGSGP
                     SLALRMTTGGRFAATVRASDGRHRL"
     gene            complement(11660..13099)
                     /locus_tag="TL08_RS11760"
                     /old_locus_tag="TL08_11860"
     CDS             complement(11660..13099)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009946858.1"
                     /locus_tag="TL08_RS11760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11860"
                     /product="carboxylesterase/lipase family protein"
                     /protein_id="WP_069853592.1"
                     /transl_table=11
                     /translation="MRQLAGPVVTTPAGAVRGIRDDFGELYRAVPYAAAPTDARRFAPP
                     APHPGWSGVRDGTQPSSTAPQPARDFGRLDMTPYFGPGWVRGGEYLTVDVRTPAAGDGE
                     RPVMVFVHGGGFVTGSTSAALYDGSAFARDGIVLVTVNYRIGIPGFLDLPGAVPNRGLL
                     DVLAALGWVRDTVAAFGGDPDNVTIFGQSAGATLVGALLATPQANGLFQRAIMQSGSGT
                     GAFTPEQAHRVTVAAADALGVEPTAEAFSSITDERFMEILPALAGLDLRTGSATDPLAG
                     LSPFGLVLPSQPADTLADGPARHVDLLIGTNTEEGHLYLVPQGDLESSTEADVLAIATR
                     VYANPETGVAAHSAARPDATPGELRSAVLGDALFGAGTARMAQAHARISSGGTHVYSFG
                     YRSTALDGRLGAAHTVELPFVFDLADKPWLHGETGLLGPDPAPASLATRIHAAWVSFAR
                     TGDPGWAAYDPQHPVTEILGS"
     misc_feature    complement(12497..12499)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13132..14049)
                     /locus_tag="TL08_RS11765"
                     /old_locus_tag="TL08_11865"
     CDS             complement(13132..14049)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009946859.1"
                     /locus_tag="TL08_RS11765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11865"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_069848848.1"
                     /transl_table=11
                     /translation="MEQTPEQIVLGDVTVTRIKEFYGPVGMTPDEFFPDSPDGSWEEHR
                     GWLSPDFWNHETAECHSAIQSWLLRSEGRTILVDTGVGNHKDRPYSPVWSRLNTGYLDN
                     LAAAGVRPEDVDIVVNTHLHVDHVGWNTRLDGRRWVPTFPNATYLMTRRDFEFWDPANE
                     NESVLGRGNQNVFEDSVTPVHEEGLTHLWEGSYRIDRNLRLDLAPGHTPGSSVLTLDSG
                     GDRALFVGDLVHTALQIAEPETNSCFCENPAESRATRHRLLGHAAENKALVFPAHFGGH
                     GATEVARSGSKFTIKRWAGFSRIS"
     misc_feature    complement(14020..14022)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14188..15090
                     /locus_tag="TL08_RS11770"
                     /old_locus_tag="TL08_11870"
     CDS             14188..15090
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020418614.1"
                     /locus_tag="TL08_RS11770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11870"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_069848850.1"
                     /transl_table=11
                     /translation="MDAPGPLGDFLQARRARLRPEDVGLRELGPRRRVPGLRREELAQL
                     AGVSVSYYTRLEQGLSRGASAEVLDAIARALLLDDHERAHLHRLVGAARRMPRARRPRP
                     EKLACETRDLLRAVDGVPALVLGRRTDVLAWNTLGHALLAGHLDFLDPDDPARRPNLSR
                     MLFLDPHCRELYTDWQRKARAIVGNLRIAVSRHPDDPFLAELIGELTMKSPEFVALWGD
                     HRVAPCDAASYELHHPVVGTVTVTQQTLSIARSPEQALIVCTTALGSPAGEALALLRQA
                     GTGQEPSAEHFDGRMRSHH"
     gene            15302..16846
                     /locus_tag="TL08_RS11775"
                     /old_locus_tag="TL08_11875"
     CDS             15302..16846
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009942938.1"
                     /locus_tag="TL08_RS11775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11875"
                     /product="deoxyguanosinetriphosphate triphosphohydrolase
                     family protein"
                     /protein_id="WP_069853593.1"
                     /transl_table=11
                     /translation="MREIRRSGAGRSPSDLSAHPYRVDRDRITASPFFARLGGVTQVVS
                     PTGSGLLLHNRLTHSLKVAQIARGIAERLTADPAAQRLVAKLGGLSADVVEAASLAHDL
                     GHPPFGHLGEQVLDRLARNRFGLADGFEGNAQSFRIVTTIDTGGTATAGLDLTAAVRAA
                     VLKYPWTRLSHPHPHPRTMAVPPRGSAEPDDSPGTGSAKFSAYVTELDDLDQSRAAFLG
                     RIPEWQQTVEAAVMDTADDIAYAIHDLDDFHRVGVLQHATVWAELHGWLSRAAELRNLS
                     EDELADRARQPGHALEGLRRRLHWKDSWIVDDEAFAEAVDRVEREVVDRLLAVPFDGSV
                     EAEQAVASFSASWTSRLVAGVEVLAEPTNRSANIVLAPRQWHEVQVLKFVHRHFVLLRP
                     DLALHQRGQARLLTALVEALEQWLTDRMEAARLPRRLHDLVELAHEEYRSLAARDASLL
                     TGPTGEIPSGPDAVASLARGRAVVDFVASLSDRQAVALLDALSGRSGQTWTDAFVL"
     gene            16905..17504
                     /locus_tag="TL08_RS11780"
                     /old_locus_tag="TL08_11880"
     CDS             16905..17504
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015803846.1"
                     /locus_tag="TL08_RS11780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11880"
                     /product="hypothetical protein"
                     /protein_id="WP_069848851.1"
                     /transl_table=11
                     /translation="MTGGRLPGNAHASTGSAASADALEQVAAAVLGSAEYRSAELLDVL
                     DGRMAERLDVVRVGDDVLPQLAHEGSVSGALAAARRALRAGGLVVAAVPELSGLRSLRP
                     TAPPPRVTGAGEDRQITVQLWDWSEDGTGYGLEVVRLHRRDGDWEVAHSTATRHRVLAR
                     DQIAQAFQIAGFVAVQRLSPGESGHPLPVWVAVAPR"
     gene            17623..18321
                     /locus_tag="TL08_RS11785"
                     /old_locus_tag="TL08_11885"
     CDS             17623..18321
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637140.1"
                     /locus_tag="TL08_RS11785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11885"
                     /product="acVLRF1 family peptidyl-tRNA hydrolase"
                     /protein_id="WP_069848853.1"
                     /transl_table=11
                     /translation="MSRVRSVAGGGRAVEIEPERLAGWFGRFAERHGGLAETTTSATQL
                     QITAADGAAVSVAVPFGGLTDESVAAIGTEQGAPERAVEALTAHVSRSRRIGLVLVRLG
                     GFSVGVAVDGAVVSSRSGRRQVHGRNKAGGWSQQRFARRRAGQARVSLSAAAEATFEVL
                     LPAVPTLEAVVFGGDRHAVDELRADNRLAPLFAIAEPRLLDVVEPRRVVLDDAAQRARA
                     VEVVVVDPPA"
     gene            18699..20327
                     /locus_tag="TL08_RS11790"
                     /old_locus_tag="TL08_11890"
     CDS             18699..20327
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020645324.1"
                     /locus_tag="TL08_RS11790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11890"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_069848855.1"
                     /transl_table=11
                     /translation="MITATDLELRAGSRILLSEANLRVQAGDRVGLVGRNGAGKTTTLK
                     VLAGEGAPYGGETRRTGELGYLPQDPREGDLSVSAKDRVLSARGLDELLRDMEKSQTAM
                     AELVDDSKRDAAIRRYGRLEDRFSSLGGYAAESEAARICSNLGLADRILNQSLSTLSGG
                     QRRRVELARILFAASESGPGGKSATTLLLDEPTNHLDADSIVWLRDFLRSHTGGLIVIS
                     HDVELLAAVVNKVWFLDATRGEVDIYNMEWKRYLEARATDEKRRRRERANAEKKASALM
                     AQADKMRAKATKAVAAQNMAKRADKLLAGLDEQRVSDKVAKIVFPAPAPCGRTPLTAEG
                     LSKSYGSLEIFTGVDLAIDRGSRVVVLGLNGAGKTTLLRMIGGRETPDAGSVIPGHGLR
                     IGYYAQEHETLDHSASVWANIQHAAPDAPAQQLRTLLGAFLFTGEQLDQPAGTLSGGEK
                     TRLALAGLVSSAANVLLLDEPTNNLDPASREQVLEALRTYQGAVILVTHDPGAVQALEP
                     ERVILLPDGTEDHWSDDYLELVQLA"
     misc_feature    complement(20387..20407)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 25.05"
                     /tool="antismash"
     gene            20505..20714
                     /locus_tag="TL08_RS27055"
                     /old_locus_tag="TL08_11895"
     CDS             20505..20714
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003071237.1"
                     /locus_tag="TL08_RS27055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_11895"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_075740427.1"
                     /transl_table=11
                     /translation="MADLKKGARITGAARDKLATDLKKKYEKGASIRALAESTGRSYGF
                     VHRVLSESGVQLRGRGGATRTKKK"
ORIGIN
        1 tggaatccgc cgagatcgtc cggcgcgggt tcgacgagtc ggccacctgc tccgcatcgt
       61 gtgcactctg cttgctgatc gcccgaccac cgatcgcctc gcccgacatc acggggcaga
      121 agggtagccg tgaccgacag ttccggaacg ccggatcgcg caagtcggtc gagcaaggtg
      181 gcaaagccgc ccattggagt cgctcatgct gcgagggcct gcctgcggca cgatgaggat
      241 cagccgaggt gatcatggtc gacaccgagg gaaagggctg tcgccgtgac gccactcacg
      301 ctggcggacg tgccggttga tcgcccgctc gaattaggta acattcgcgt tgtggaattc
      361 gtcggaccgt cggctgcggc tgcgaacgac gccgagcacc ctaccgtggt gcccggcgtg
      421 cttccgcgtg cgcaatcgac gcccgaggcc actccggcgt cgagcgagcc cgacgcaccg
      481 acggattcga ccaccggcac ctctggcgcc gagggacgca ccaggcacgc cgtggccagg
      541 ctgctcctcg agaacggccc cgccaccgcc gcggtcatcg ccgaggaatt gggtctcggc
      601 caggctgcgg tgcgacggca cctcgacgcg ctgatcgccg acggccaggc gagcaccagg
      661 caggccccca agggcccgag ggggcgaggc cgccccgccc ggctgtacct gctcaccgag
      721 gccggtcgcg cccgattcgg ccatgcctac gacgatctgg ccgtctccgc gctgcgtttc
      781 ctggccgagc acgtcggcga acacgccgtg acggccttcg ccaggcagcg ggtcgccgac
      841 ctcgtggtcc gccatcgggc cgttgtcgcc gccgccgagc ccgaagcccg tgccgaggtg
      901 ctcgccgagg cgctcaccag cgagggttac gcttcctcga cccggcgggt caggtcggga
      961 gagcaactct gtcaacacca ctgtcccgtc gcgcacgtcg ctgcggagtt cccgcaactc
     1021 tgcgaggccg agacggcgtt gttcgccgag ctcctcggca cccacgtgca acgactggcc
     1081 acgatcgctc gcggcgacgc ggcgtgcacc acgcacgtcc cacatgccga gcgggcaccg
     1141 gagcacaccg atatcgagca gtcggaatcc cccgactgtt cgtccaccag tctggtgccc
     1201 gctaccgcga caccagttca gaccgccccg aatccggatg gaggggaacc cgcatgactg
     1261 ccgctgccga gcagcgaaca cccaccactg cgtcgaccac ccagggccag cagccgctga
     1321 cccaggagga gacgctcgcc acgctgggta actacgagta cggctgggcc gactccgacg
     1381 cggcgggcac cagtgctcgc cgaggtctga acgaggacgt ggtccgagac atctcgggca
     1441 agaagagcga gcccgactgg atgctgcaga cccgcctcaa gggtctgagc ctgttcgagc
     1501 gcaagccgat gccgaactgg ggcgccgacc tctccggcat caacttcgac gcgatcaagt
     1561 acttcgtccg gtcgacggag aagcaggcca ccagctggga ggacctgccc gaggacatca
     1621 agaacaccta cgaccggctg ggcatccccg aggcggagaa gcagcgcctg gtcgccggtg
     1681 tcgccgctca gtacgagtcc gaggtcgtct accacaagat ccgggaggac ctcgaagagc
     1741 agggcgtcat cttcctggac accgacaccg gtctgaagga gcaccccgag ctcttccagg
     1801 agtacttcgg ctcggtcatc ccggcgggcg acaacaagtt ctccgcgctg aacgcggcgg
     1861 tctggtccgg cggctccttc atctacgtgc ccaagggcgt gcaggtggac atcccgctgc
     1921 aggcctactt ccggatcaac accgagaaca tgggccagtt cgagcggacg ctgatcatcg
     1981 tcgacgaggg tgcctacgtg cactacgtcg agggctgcac ggcaccgatc tacagctccg
     2041 actcgctgca ctccgccgtg gtggagatca tcgtgaagaa gggtggtcgg tgccgctaca
     2101 cgaccatcca gaactggtcg aacaacgtct acaacctggt caccaagcgc gccaaggccg
     2161 aagagggcgc gaccatggag tggatcgacg gcaacatcgg ttccaaggtc acgatgaagt
     2221 acccgtcggt ctacctgatg ggcgagcacg ccaagggcga ggtcctctcg atcgccttcg
     2281 cgggcgaggg ccagcaccag gacaccggcg ccaagatgac gcacctcgca ccgcacacct
     2341 cctcgaccat cgtctccaag tcggtggcca ggggcggcgg ccgggcctcc taccgaggac
     2401 tggtccgggt gaacaagggc tcgcaccacg cgaagtccac ggtcaagtgc gacgcgctgt
     2461 tggtcgacac gatcagccgc tccgacacct atccctacgt ggacgtccgc gaggacgacg
     2521 tggcgatggg acacgaggcg accgtgtcca aggtcagcga cgaccagctc ttctacctga
     2581 tgtcgcgcgg cctcaccgag gacgaggcga tggccatggt ggtgcgcggc ttcgtcgagc
     2641 ccatcgctcg cgagctcccg atggagtacg cactggaact caaccgcctg atcgagctac
     2701 agatggaagg ggccgtcggc tgagatggcg acaccgactc acacctcgga tgtcacaccc
     2761 ggcgttgcgg gcaaggccca ctcgcacggt ggtccggtga tcccgcagtc ctcccgaggg
     2821 gaacgcttca cctcctacga cgtggccgcc ttcgaggttc ccggcggccg cgaggaggac
     2881 tggcgcttca ccccgctgcg gaggctggcg ggcctgcacg aggccgccaa gaccgtggac
     2941 ggcagcctca ccgtggaggt caccgccgag gcgcccgtga ccgtggagac cgtggaccgt
     3001 tccgacgcca ggatcggtca gggcggcgtg cccgccgacc gggtggccgc tgccgcctgg
     3061 tccggtttca ccgaggccac cgtggtcacc atccccggtg acacccggcc cgacccgatc
     3121 tcggtcgtgg tgaccggtcc gggcgcggac aagtcggcct acgggcacct gcacctgcgg
     3181 gcggaggcgt tcgccgaggc caccgtggtc ctggactacc ggggctccgg cgcggtcgcc
     3241 gacaacgtgg agatcgtggc gggcgactcg gcccgactga ccgtgatcac cctgcacgac
     3301 tgggcgaccg acgccgtcca tgtcggcgcc cagcacgcct cggtcggtcg ggacgccacc
     3361 ctgcgccact tcgccgtcac cctcggcggc gacctggttc ggatctcctc gacggtgaac
     3421 taccgcgaca ggggcggcga cgccgagctg ctcgggctgt acttcgccga cgcgggccag
     3481 cacctggaac accggatgct ggtggaccac tccgtgccca actgccggag caacgtggtc
     3541 tacaagggcg cgctgcaggg cgagggcgcc cacacggtgt ggatcggcga cgtgctgatc
     3601 caggctgccg cggaggccac cgagaccttc gagctgaacc gcaacctgat tctcaccgat
     3661 ggtgcgcgtg ccgactcggt gccgaacctg gagatcgaga ccggggagat ccagggtgcc
     3721 ggacacgcca gcgccacggg tcggttcgac gacgagcagc tcttctacct ccaggccagg
     3781 ggaatcccgg tcgaggtggc ccgcaggctc gtggtccggg gcttcttcgg cgagatcctg
     3841 cagaagatcg cggtgcccga ggtccgcgag cggctcgagg ccgctatcga ggccgagctg
     3901 gcggcggtcg gcacatgacg atgaccccgg tgtgcgaggt cgacgagctg cccgagggga
     3961 agcccgttcg ccacgatgtc gacggtgtct ccgtcgtcct cgtgcgcgac gcccacggcg
     4021 tccacgcgct gcacgatgtc tgctcgcacg ccgaggtggc cctgtccgag ggcgacctgg
     4081 tcaccaaggg cggcaagctc atgttggagt gctggttgca cggctcgtgc ttcgacctcc
     4141 gcaccggggc tccgaccggt ctgcccgcca ccgatccggt ggcggtgttc gcgaccgaga
     4201 tcagccaggg ctgggtccgt gtcgacccgg cacgcaggat cgcgggctga ggcgacggcg
     4261 tccgcgccac gcccacccgc gccttcccca gacttaccag cgaaatcagg agaacgaaga
     4321 ccgatggcca ctctggaaat caaggatctg cacgtctcgg tgtccaccga cgacgcgccc
     4381 aaggagatcc tcaagggcgt cgacctgacg gtgcgcggcg gcgagaccca cgcgatcatg
     4441 gggcccaacg gctccggcaa gtccaccctc gcctacgcca tcgcaggcca cccgaagtac
     4501 gaggtcacct ccggttcggt gctgctggac ggcgaggagg tgctggagat gaccgtggac
     4561 gagcgggccc gcgcaggcct gttcctggcc atgcagtacc cggtcgaggt ccccggcgtc
     4621 tcgatgtcga acttcctgcg ctcggccgcc acggcggtcc gtggcgaggc ccccaagatc
     4681 cgccactggg tcaaggaggt caagcaggcg atgacggacc tcgacatcga gccgtccttc
     4741 gccgagcgca gcgtcaacga gggcttctcc ggtggtgaga agaagcggca cgagatcctg
     4801 cagctcgacc tgttgaagcc gaagttcgcg gtcctcgacg agaccgactc cggtctggac
     4861 gtcgacgccc tgcgtgtcgt ctccgacggc gtcaaccgct acaccgcagg cggcgacaag
     4921 ggcgtgctgc tgatcacgca ctacacccgg atcctcaagc acatcgcgcc ggaccacgtc
     4981 cacgtgttcg cgggcggccg catcgtggag tccggcggcg ccgagctggc cgaccagctc
     5041 gagcgggacg gctacgtgcg gttcaccggc aacaaggaga ccgccgcagt ctgataccga
     5101 tgtcctggca gtccgccgat cagggtgcgc gcacccggcg gcggacgagg accggtatcc
     5161 gaggcaggcg aggatcgtga ctgaagaagg gggcggcggc catggcgacc acggcgacac
     5221 cgctggacat cgcaagcatc aaggctgact tcccgatcct cgccaggacg gtgcgagacg
     5281 ggaagccgct gatctatctc gactccggcg ccaccgcaca gcggccccgt caggtgctcg
     5341 acgccgagcg ggcgttcctg gagacctcca acgcggcggt gcaccgcggg gcgcaccagc
     5401 tgatggagga ggccaccgac gcctacgagt cggccagggc gcggatcgcc gcgttcatcg
     5461 gcgtcgacga cgacgaggtg gtgttcacca agaacgccac cgagggcgtc aacctggtgg
     5521 cctatgcgat gggcaacgcg gcgacctccg gcccggaggc ggcgcgcttc cggctcggcc
     5581 ccggcgacga gatcgtggtg accgagatgg aacaccacgc caatctcgtg ccgtggcagc
     5641 agctgtgcgc caggaccggc gcgacgctga agtggttcgg cgtcaccgac gagggcaggc
     5701 tcgacctgtc ggatgccgac tcggtggtca ccgagcacac caaggtggtg gccttcaccc
     5761 accagtccaa cgtgctcggc acggtcaatc cggtgtcgga gttggtggcc ctggccaagc
     5821 gggtgggcgc gctgaccgtg ctggacgcgt gccagtcggt gccgcatgcc gccatcgacc
     5881 tgcacgcgtt ggacgtcgac ttcgcggtgt tcagcgggca caagatgttg ggcccgtccg
     5941 gcgtcggggt gctctacggc aggcgcgagc tgctggccgc gctgcccccg ttcctgaccg
     6001 gcggctcgat gatcgagatc gtgcggatgg agtcctccag cttcgcggcc ccgccgcagc
     6061 gtttcgaggc gggtgtgccg atgacctcgc aggcggtggc cttgggtgcg gccgtggact
     6121 atttgcgggt ggtcggcatg gatcgcatcg ccgatcacga gaagaccctc gtcgaggcca
     6181 cgctggccgg tctcgccgag gtgcccggtg tgcggatcgt gggaccctcc gacaccgtgg
     6241 cgcgaggcgg cgcggtgtcc ttcgtcatcg atgacatcca cccgcacgac gccggtcagg
     6301 tgttggacag cctcggcatc gcggtgcggg tcggacatca ctgtgcctgg ccgctgcatc
     6361 gacggctggg catccaggcg acgatgcggg ccagcttcta tctgtacaac gacctgtccg
     6421 acgtcgaggc gttggtggca ggcgtccggg agagccgtcg attcttcggc gtcgactcgg
     6481 atggggcgac ctcggccgcg ggggtggcct gacatgcagc tggaccagat gtaccaggag
     6541 atcatcctgg atcactacaa gcatccgcac ggccacggcc tgcgggaacc gttcgacgcc
     6601 gaatcacacc aggttaatcc gatgtgtggt gacgaggtga ccctgcgggt ggccctgtcc
     6661 gggcacgatt cggccgccac ggtcgtcgac gtctcctatg agtcgcaggg ctgctccatc
     6721 agccaggcat cgacctcggt gttgaccgat ctcgtcgtcg gtcgaccgct gcccgaggtc
     6781 atgacggtct cggaggcgtt cctggagctc atgcaggggc ggggcaaggt ggagccggac
     6841 gaggacgtcc tcggcgacgg catcgccttc gccggggtgg cgagataccc ggcacgggtg
     6901 aagtgcgcgc tgctgggttg gatggcgttc aaggacgcgg tgagtcgcgt cgtcgacgag
     6961 gtgaggacag tatgaccagc gtggcagacc agaattcgga tcccggggcc gagcaggtgc
     7021 agcgcggtgt cgagggactc cccgagccgc ccgcccctcg cgccgacaag ccggagatcg
     7081 aggacatcga ggaggccatg cgcgacgtgg tcgaccccga actcggcatc aacgtcgtcg
     7141 acctcggtct ggtgtacggg gtgacggtcg acgacagcaa catcgcgacc atcgacatga
     7201 cgctgacctc ggcggcctgt ccgctgaccg acgtcatcga ggaccagacc cggtctgcac
     7261 tcaccggcgg ccccgacggc ggtctggtga gcgacatccg catcaactgg gtgtggatgc
     7321 cgccgtgggg cccggagaag atcaccgacg acggccgcga ccagttgcgg gcgctgggct
     7381 tcaccgtctg agcacgacca cggacttcac aacgcggccg gaccccgatc gggatccggc
     7441 cgcgttgtcg ttccgcaggt gggtcttgac tcggatcagc gcccacggcg aggtctgtcg
     7501 aagcgcccgg ccttgacgga ggtgaagaag tcggcggact gcgagggcgt cagggccagc
     7561 gccccggccc cgggcgcctt gctgtcccgg atggcctggg catcgcccac ccaggccaac
     7621 tcgacgcagg tgccattgtt cgcactacgg ctggacttcc gccaaccact cacccgagtc
     7681 gacgtgtcca tgacgttcct cccatgagtc ctactcagcg atcatcgact tgatcagcgc
     7741 cagcgactgg gtgggaccga gcgcgacacg ctgcaagttc tctactaccc gctatctgag
     7801 gtgtctaaag gactgctgtc tcagactggg cgaggtctgt cgaagcgccc ggccttgacg
     7861 gcggcgaaga agtcgccgga ctgggtgggc gtcagggaca gcgccccggc ctcgggcgcc
     7921 ttgctgtccc ggatggcctg aatctcgttg ttgtccaagc cgacttcgac gcagttaccg
     7981 ccggtgtcgg cgctacggct ggatttacgc cagtacgtcg ggttcacgcg gctgtcggtg
     8041 gggttcgatg tggttcgcac ggttactcct cacactcgcg tcggttggat cttgtgaccc
     8101 tcgggggagt ccatccaaat gtccgccggg tcaaggaagc ttggtttcgc tgtctcgccg
     8161 aagacagatc gaaccggtgc ccggcccgcc gcagaccggg ccgcccctca gccggtggct
     8221 cgccggcggg gcggcatctg ggactgcgat gggctctgtg ggggagtgcc gcgcagctcg
     8281 tcgacctggt cggaggtgga tcggccgacg acccagctgg tgccgagcag tgccttggcc
     8341 ctcgatttca acggcgacag tcgacgggag gcgtcgtgat ggctcggcac ggtgccgggt
     8401 gcgcagacca atgaggccag cgacaccgtc accggtcggc cctccgcctc ccgttctacg
     8461 tccagcagtt ctgctcccag cggcatcagt tggtcgaggt cgcagaccac caggaaatcg
     8521 tcgccgccga cgtggccgac cacgacaccg ggcattcccg ctgcaaggtc ggtcagatgc
     8581 ctgcccaacg accggatcag ctcgtcgccc gccgcgaagc cgaccgtgtc gttgacgccc
     8641 ttgaaaccgt cgatgtccag ccagctgacg gtgaacgcct cgccgtcggc cagccgttga
     8701 tcgatctcca tggcgaccga atcggtgccg ggcagtcggg tgagcgggtt cagggtggcg
     8761 gcctgttcca ccttcatctc cgccacgccc cggaacagat caccggcccg caccacgccg
     8821 agacaacgtc cggcctcatc gaccacgacg aggtctacgt acatctgatc cggcccggag
     8881 tcggcgacca ggtccagggc ctcgaccacc gtgttgtgcg ttccgacgag tttcggttcc
     8941 tcggcgagtc gtaacgcctc gcggcgggcg tgcagggcgt gcccgtacgg gcccgtcacc
     9001 gcgagcagga agcgattgcg gtcgaccaac cggtgcggcc gcccggtccg gtcgagcaac
     9061 acgacgctgg tgctgtcggg gtggtcggcg aagacgacac gcacctcgtc ggcggtagcg
     9121 gtggtcggca gcggcacggc gggctggagg aaatcggtga cgcggggacc cgccgagcgc
     9181 gccgcgatcc ggggtgcctg cacctgggac agttcggaga gcaccgaact cacggccacc
     9241 tgtgacatcg gcctgcgcga cggcgccgcg atcagatcgc cttggacgag accgacgcct
     9301 gctgctcgca gcgcggtgag ttgttcctcg gtgtcgacgc cgtggacggc cagctgcatc
     9361 ccgctgtggt cggcgaaggt caccatcgac tcgatgaacg cgagtgtggc cggttcggca
     9421 tgtgcccggg tggccagggt ctggtcgagc ttgagcaggt tgatcagccc ggaggccacc
     9481 agccgcaggg gtgcatcgcc ctcgccgagc ccgtcgaggc ccagccggta gccgcgctcg
     9541 tgcaacacgc ctaacccgtt gagcagtgcc tcgtggtcca ggcggtagaa cggcggaccg
     9601 acctccaggg tcacctgatg cggcggtcgc ccggcttcgt ccaagaccgc gtcgagcagt
     9661 tcgaagcgct cgatatcgta ggcgatcgtg cctgccagca cgttgatgtg cagcggcaac
     9721 ctggttccgc ccgctgccgc ctccgatgcg gcggccatgg ccaactcgac gtcgagttcg
     9781 gtgagcttgc gggcctgcac cgcctggcgg aacagctcac gcatctcacc gccatgcggc
     9841 cggggaactg cttcgagcgc gacgatcccg ccggtggcga ggttgaccag cggctggaag
     9901 gcgaagcgca cattctgcgg cggcgcggtc acctgaccat gctcccccct gtccgagatc
     9961 gaagacgaga ccgaggtcgc gtccttgtct gtctgctccg tcacagtcgg tgtctgccat
    10021 cgctggcacg taccgtggcc gcgaaccgac cgccggtggt catgcgcagg gccaaggacg
    10081 gccccgagcc cgccagtacc gcgaccatcg ccttggccgt gcccagcaca tcctccctat
    10141 cggagagata agaggtccgc acgtcggtcg gaatccggaa gaacgacgtg aagaactcag
    10201 acgactcggc gcggtccagg gtgagcagca cctccagacc atagcgccgc aacgcgtgca
    10261 ccatgcgtgc cttgggtggc caaagcacgt gtcgggccgc cctggtcacc gcagacggac
    10321 cgcttcgaac ccctgccgcc agcgccgtgg ccatggccgg gaccagccgc agggcggtcg
    10381 ccaacccgta tccggacgcc ggatggacca gtccggcggc ggccccgaaa ctcatggttc
    10441 gggcggtcgt cgcggctggc cggtcgagat cgatccggac tcgttccctg cgccgcacac
    10501 cactgagatc cacgccgtgc cctgccatcc gccgggacaa ccggttgcgc agctccccga
    10561 aggacagggc cggtcggccc gccagacagg tctcctcgat cagaacctca tcgtcgccca
    10621 gcggcaccgc gtagcagaag ctcggggttc gcccgacctg ttccaccggc cgccagtcca
    10681 tgagaatcgc ctcgcccggg gcaacatagc ggcgagcggc tgtggacggc agcacgacgc
    10741 cgaatgcggt ctgcgcggcg gattgtcgcc gcgcaccgca tcgatcggtt ccggccgagc
    10801 cgaggcgggt tccggcggca gcctcgctac agtgaccgac agccggcgag cttccccgcc
    10861 gccaccgacc ggtgccactg gcgtccacga acagcccggc ttcgatcgac cggccgtcgg
    10921 ccaacagcac ggtgcacccg gatccgctgt gctccaccgc ccgcacccgt ccggtgtgct
    10981 ggacgatgtc gggccgggcg agttccgcgc gcaacgccgc gttgtccaac acgcagtaac
    11041 tccggtcggt cagccgccgc tgtccggagt cggtgacgac cagcacagtc tccgcgcagg
    11101 tggcgatcac cctgtcgggc agaccgggga gttcgtcgag ccacagtccg taggtcgccc
    11161 gccaaggacg ctgcggagcc ggatcgatca gcgtcaccga cagcccgaga tccgcgcagg
    11221 ccgcgccaag agcccggcct gcaggcccgg ctcccgcgat gacgatgtcg accactccgc
    11281 catcactacc aggtttctcc gacgaaatgg gacacaccga tctggtcgcc cgcctgcgac
    11341 ccgcctgcga cccggctgca tctcccactg gttgggaccc gtcgctcaat cctgtcgggt
    11401 caattcgagg ccgggcgggg agccgatggg ccaatcctcg gccggcacct gaacgcgctg
    11461 cgccaaacac ttcgtccgcg ctggggccgc atcggttcgg tgggcacctg ttgcccggga
    11521 accacccggc tccagcgttc tgggaagttc gccggtgcct acgaacgggt cttcgttcag
    11581 cctgcgtcgg gttcgggggc gggcaccgcg gtgggtggga tcgccgatcg ttcggacgcc
    11641 tccccgtccg ggacgcggat cagctgccga ggatctccgt cacggggtgt tgcgggtcgt
    11701 aggcagccca gccggggtcc ccggttctgg cgaacgagac ccaagcggcg tgtatccgtg
    11761 tcgcgaggct cgccggggcg gggtcggggc ccaatagacc ggtctccccg tgcagccatg
    11821 gtttgtcggc gaggtcgaat acgaagggca gctcgacggt gtgggcggcg ccgagtcgcc
    11881 catccaaggc ggttgagcgg taaccgaacg agtagacgtg cgtgccgccg ctcgaaatcc
    11941 gtgcgtgtgc ctgtgccatg cgggccgtac cagctccgaa cagggcatct ccgagcacgg
    12001 cggaacgtag ttcaccaggt gtagcgtccg gtcgggccgc gctatgcgcg gcgaccccgg
    12061 tctccgggtt cgcgtacacc ctggtggcga tggcgagcac gtcggcctcg gtggaggact
    12121 ccaggtcgcc ctgcggcacg aggtagaggt gcccctcttc ggtattggtg ccgatcagca
    12181 ggtctacgtg gcgggccggg ccgtcggcga gagtgtcggc gggttggctt ggaagaacca
    12241 gaccgaacgg actgagcccg gccagcggat cagtggcgga gccggtgcgt agatcgagac
    12301 ctgccagggc cggaaggatc tccatgaagc gttcgtcggt gatcgaggag aaggcttcgg
    12361 ctgtcggttc gacacccagc gcgtcggccg ctgcgacggt gactcggtgc gcctgctccg
    12421 gggtgaaggc gccggtaccg ctgccgctct gcatgatcgc ccgctggaac aggccgttgg
    12481 cctgtggcgt cgcgagtaac gctccgacga gtgtggcgcc tgcggactgg ccgaagatcg
    12541 tgacgttgtc cgggtcgccg ccgaacgccg cgaccgtgtc gcgtacccag ccgagcgcgg
    12601 cgagcacgtc gagcaatcct cggttgggca cagctcccgg taggtcgagg aaaccgggaa
    12661 taccgatgcg gtagttcacc gtgacgagga cgatgccgtc gcgggcgaag gcactgccgt
    12721 cgtacagcgc ggcgcttgtc gaaccggtga cgaatccgcc gccgtgcacg aagaccatga
    12781 cggggcgctc gccgtcgccg gcggccgggg tgcggacatc gacggtcagg tactccccgc
    12841 cccgtaccca gccgggtccg aagtaggggg tcatgtcgag cctgccgaag tcgcgggccg
    12901 gttggggagc cgtggacgag ggttgcgtgc catcgcgcac cccggaccag cccgggtgcg
    12961 gtgcgggcgg ggcgaagcgg cgggcatcgg tcggtgctgc cgcgtagggg acggcacggt
    13021 agagctcgcc gaagtcgtcg cggatgccgc gcacggcgcc cgccggtgtt gtgacgaccg
    13081 ggcctgcaag ctggcgcacg gaatacttcc tttcctggtt cgttcgggtc atcaggagat
    13141 gcgggagaag cccgcccagc gcttgatcgt gaacttcgaa ccactgcgtg ccacctccgt
    13201 ggcgccgtgg ccgccgaagt gcgctgggaa gacgagtgcc ttgttctcgg cggcgtgacc
    13261 gagcagcctg tgtcgggtgg cacgggactc ggccgggttc tcgcagaaac aggaattggt
    13321 ctccggctcg gcgatctgca gcgcggtgtg caccaggtcc ccgacgaaca gggcccgatc
    13381 gccaccggag tccagcgtca gcacggacga gccgggggta tgcccgggag cgagatcgag
    13441 ccgcaggttc ctgtcgatcc ggtacgaccc ttcccacagg tgtgtcagcc cctcttcgtg
    13501 gaccggagtg acactgtcct cgaagacgtt ctggttgcca cgacccagca cagactcgtt
    13561 ctcgttggcc gggtcccaga actcgaagtc ccgccgcgtc atcagatacg tggcgttcgg
    13621 aaaggtcggg acccacctcc gcccgtcgag gcgggtgttc cagccgacgt ggtcgacatg
    13681 caggtgggtg ttgaccacga tgtcgacatc ttcgggtcgc acccctgctg cggcgaggtt
    13741 gtcgagatat ccggtgttca gcctgctcca caccggcgag tacggccggt ccttgtggtt
    13801 gccaacaccg gtatcgacga ggatcgtgcg cccttcgctg cgcagcagcc aggactggat
    13861 cgccgagtgg cactcggctg tttcgtgatt ccagaagtcg ggcgacagcc agccacggtg
    13921 ctcctcccag gagccgtcgg gactgtccgg gaagaactcg tcaggagtca tccctaccgg
    13981 accgtagaac tccttgatgc gggtgacggt gacgtcgcct aaaacgatct gttccggagt
    14041 ctgttccatg tgagccgtcc tcgaattcgc ggtatgtgcc cgaatacgac cgagcctgga
    14101 caccgggacg agcacgaacc actcccgcgt tgtggtaccc ctcgcagggg gtggttgggg
    14161 tcgggtcgtg ccccgaatac tggggtcatg gacgcacccg gcccactcgg cgacttcctc
    14221 caagcccgac gggcccggct gcggccggag gacgtcggcc tgcgcgaact ggggcctcgc
    14281 aggcgggtac ccgggctgcg gcgggaggaa ttggcccaat tggcaggcgt cagcgtctcc
    14341 tactacaccc gactggagca gggcctgtcc cgaggggctt cggctgaggt gctcgacgcg
    14401 atcgcccgcg ccctgctgct cgacgaccac gagcgtgcgc acctccaccg gctcgtcggc
    14461 gccgcccgcc gtatgccccg cgcgcgacgc cctcggcccg agaagctcgc ctgtgagacg
    14521 cgggatctcc tccgtgccgt ggacggcgtc ccggcgctgg tgctcggcag gcgcacggac
    14581 gtgctggcgt ggaacaccct cgggcacgcc ctgctggccg gtcacctgga cttcctcgac
    14641 ccggatgatc cggcccgacg gccgaacctg agtcggatgc tgttcttgga cccgcactgc
    14701 cgggagctgt acacggactg gcagcgcaag gcccgtgcga tcgtcggcaa cctgcggatc
    14761 gccgtcagca ggcacccgga tgacccattc ctcgcggagc tgatcggcga actgacgatg
    14821 aagagcccgg aattcgtcgc actctggggc gaccaccggg tggcaccctg tgacgccgcg
    14881 tcctacgaac tgcaccaccc cgtcgtcggc acggtgaccg tgacacagca gacgctgtcg
    14941 attgcccgct cgccggaaca ggcgctgatc gtgtgtacga ctgcgctcgg ctcacccgca
    15001 ggggaggcgc tcgcgctact ccgacaggcg ggcactggcc aggagccctc cgcagagcac
    15061 ttcgatggtc ggatgagaag ccatcactag gggagggttc gccggcgtct cgatgcaggc
    15121 ggctcgggac gtcaccgtct cccagcggtg agttcgggcg gccggaaccg gtcgatccgc
    15181 cgccgggcac cgagaccatg gcaggcagcc ggggcacgtc ggtccggaca cgggccggag
    15241 ccccacccga ccgtctcggg gatacggtca tccggtgacc gaggagacga cactcgagaa
    15301 gctgcgtgag atccggcgtt ccggcgcggg ccggagccca tcggatctgt ccgcccaccc
    15361 ctatcgggtg gaccgggacc ggatcaccgc atcgcccttc ttcgcgcggc tcggcggcgt
    15421 cacccaggtg gtcagcccga cgggatccgg gctgctgctg cacaaccggc tcacccacag
    15481 cctgaaggtc gcccagatcg ccagggggat cgccgagcgg ctgaccgccg atccggcggc
    15541 acagcgcctg gtcgcgaagc tcggcggcct cagcgccgac gtggtcgagg cggcgtcgct
    15601 cgcgcacgac ctcgggcacc cgccgttcgg gcacctcggg gagcaggtgc tcgatcggct
    15661 ggcccgcaac cgtttcggtc tggccgacgg cttcgagggc aatgcccagt cgttccggat
    15721 cgtcaccacg atcgacaccg gtggaaccgc caccgcaggc ctcgacctga ccgcagcggt
    15781 gcgtgccgcc gtcctcaaat acccgtggac ccggctctcg cacccgcatc cgcatcctcg
    15841 gaccatggcg gtcccgccgc gcgggtccgc ggagcccgac gactcaccgg gcaccggctc
    15901 ggccaagttc tcggcgtatg tgaccgagct ggacgatctc gatcagtccc gggcggcctt
    15961 cctcggccgg atacccgagt ggcagcagac cgtcgaggcg gccgtgatgg acaccgccga
    16021 cgacatcgcc tacgcgatcc acgatctcga cgacttccat cgggtcggcg tgctccaaca
    16081 cgccacggtg tgggccgagt tgcacggctg gctcagccga gcggccgaat tgcgcaacct
    16141 ctcggaggac gagctggccg atcgggcccg tcaaccaggc cacgcgttgg agggactgcg
    16201 ccgccgactg cactggaagg actcctggat cgtcgacgac gaggcgttcg ccgaagcggt
    16261 ggaccgggtg gagcgggagg tggtggatcg acttctcgcg gtgcccttcg acggttccgt
    16321 ggaggcggaa caggcggtcg cctcgttctc ggcgagttgg acgagccggt tggtcgccgg
    16381 tgtcgaggtc ctcgccgaac cgacgaaccg gtcggccaac atcgtgctcg cgccccggca
    16441 gtggcacgag gtccaggtcc tgaagttcgt ccaccggcac ttcgtcctgc tgcgccccga
    16501 cctggccctg caccaacgcg ggcaggcccg actgctgacc gccctggtcg aggcgttgga
    16561 gcagtggttg accgatcgaa tggaggcggc gcggctacca cgcaggctgc acgacctcgt
    16621 cgagctggcg cacgaggagt accggtcgtt ggcggcccgg gacgcgagcc tgctcaccgg
    16681 ccccaccggg gagatcccca gtgggccgga cgccgtggcc tcgctggcca gaggtcgtgc
    16741 ggtcgtcgac ttcgtggcct cgctcagcga ccgacaggcg gtggcactgc tggacgcgtt
    16801 gtccggccgt tccggtcaga cctggaccga cgccttcgtg ctatgacgcg gcggacggca
    16861 ccacgggctg ggctcgggcc cccgatggat ctaggctctt cgagatgacc ggcggccgac
    16921 ttcccggtaa tgcccacgcc tcgacgggct ccgccgcgtc tgcggacgcc ctcgaacagg
    16981 tcgccgcggc ggtcctgggt tccgccgagt accgctcggc cgaactgctc gacgtcctag
    17041 acggtcggat ggccgagcgg ctggatgtgg tgcgggtggg cgacgacgtc ctgccgcaac
    17101 tcgcccacga gggcagcgtg agcggggcgc tggccgccgc ccgccgcgcc ctgcgcgccg
    17161 gtggactcgt ggtggccgca gtccccgaac tcagcggact acgcagcctg cgtccgactg
    17221 cgccgccacc gagggtcacc ggcgcggggg aggaccggca gatcaccgtt cagctgtggg
    17281 actggtccga ggacggcacc ggctacggac tcgaagtagt gcggctgcat cgccgggacg
    17341 gtgactggga ggtagcccac agcaccgcca cccgacatcg ggtactcgcc agggaccaga
    17401 tcgcgcaggc cttccagatc gccggtttcg tggcggtaca gcgcctgtcg ccgggcgaga
    17461 gcgggcaccc gctgccggtg tgggtcgcgg tggcgccccg atgagccccg gcgctgctgc
    17521 acggcggggc gcggggacct gccgggacac gtcaccgggc ggcggccaca tcagtgcgag
    17581 acgggggatg aatcggatgc ggtactcgat gggggcccgg cgatgagccg ggtgcgcagc
    17641 gtcgcaggcg gtggtcgggc cgtggagatc gagccggagc ggttggcggg ctggttcggg
    17701 cggttcgccg agcggcacgg cggtctcgcc gagacgacga cctcggcgac acagttgcag
    17761 atcaccgccg ccgacggtgc cgccgtctcg gtggcggtgc ccttcggggg actcaccgat
    17821 gagtccgtcg ccgccatcgg caccgagcag ggcgcgccgg aacgagcggt cgaggcactc
    17881 accgcgcacg tgtcacggtc ccgtcggatc ggtctggtgc tggtgcggct cggtgggttc
    17941 agcgtgggcg tcgcggtcga cggcgcggtg gtgtcctcgc gcagcggccg ccgacaggtc
    18001 cacggtcgga acaaggcggg cggttggtcg cagcagcggt tcgcccgccg tcgggcggga
    18061 caggcccggg tgtccttgtc ggctgcggcc gaggcgacct tcgaggtcct gctgcccgca
    18121 gtgccgaccc tggaggccgt ggtgttcggc ggtgatcggc acgcggtgga cgaactccgc
    18181 gccgataacc ggctcgcgcc gctcttcgcg atcgccgaac ctcgactcct cgatgtcgtg
    18241 gagccacgca gggtcgtcct ggacgacgcg gcacagcggg cccgtgccgt ggaggtggtg
    18301 gtcgtcgacc cgcccgcctg aggcgcgctc gaccgggcgt tcgccccggg agccgagctg
    18361 ccgaggacga ggtccgcccg acagcctggg cgggccgccg gaatgcacca gatcgagccg
    18421 ccgtgtcgtc ccggcccaca ccgcgacggc gatcatggcc gttcgggctc ctcgaacacc
    18481 gtgggccgcc gccgaagcgc cctccgcgag tacgagccga cctgcgagcc aggcggccgg
    18541 gtcgtccgag gggtcggcgc gggggaattc gcgttgatcc gacccgtaca ctggggcacg
    18601 tggtccgcat cgattaaccc atgggcaggc gcgtcgtctc ttcgacgggc cgctccctca
    18661 tgcccgtgac cacacacctc ttttctcgga gttctctctt gatcactgcg acggatctcg
    18721 aactgcgcgc tgggtcgcgc atcctgctct cggaggccaa cctgcgggtg caggccggcg
    18781 accgcgtcgg tctcgtcggc cgtaacgggg cgggcaagac caccacgctg aaggtgctgg
    18841 cgggtgaggg ggcgccctac gggggcgaga cccggcgcac cggtgagctc ggctacctgc
    18901 ctcaggatcc ccgcgagggc gacctctcgg tctcggccaa ggaccgggtg ctctccgcca
    18961 gaggactcga cgagctgctc cgcgacatgg agaagtccca gaccgcgatg gcggagctgg
    19021 tcgacgacag caagcgtgac gcggcgatcc gccgatacgg caggctggaa gaccgattct
    19081 cctcgctggg cggctacgcg gccgagagcg aggccgcgcg gatctgctcc aacctcggcc
    19141 tggccgaccg catcctgaac cagtcgctga gcaccctctc cggtggccag cgccgccggg
    19201 tggaactcgc gcgcatcctg ttcgccgcct ccgagtccgg gccgggtggc aagtcggcga
    19261 cgaccctgct cctggacgag cccaccaacc acctcgacgc ggactccatc gtctggcttc
    19321 gtgatttcct gcggtcccac accggtggcc tcatcgtcat cagccacgac gtggaactgc
    19381 tggcggccgt cgtcaacaag gtgtggttcc tggatgccac ccgtggcgag gtcgacatct
    19441 acaacatgga gtggaagcgc tacctggagg cgcgggccac cgacgagaag cgccgtcgcc
    19501 gggaacgggc caacgccgag aagaaggcct cggcgctgat ggcccaggcc gacaagatgc
    19561 gtgccaaggc caccaaggcc gtcgcggcgc agaacatggc caagcgagcc gacaaactgc
    19621 tcgcggggct ggacgaacag cgggtctccg acaaggtggc caagatcgtc ttcccggctc
    19681 ccgcgccctg tggccggacg ccgttgacgg cggagggcct ctccaagtcc tatggctcgc
    19741 tggagatctt caccggcgtc gacctggcga tcgaccgggg ctcgcgggtg gtcgtgctcg
    19801 gcctcaacgg tgcgggcaag acgaccctgc tgcggatgat cggtggcagg gagacccctg
    19861 acgcgggctc ggtgatcccc gggcacggcc tgcgcatcgg ctactacgcg caggaacacg
    19921 agacgctgga tcactcggcg agtgtgtggg ccaacatcca acacgcggcg cccgacgcac
    19981 ccgcccaaca actgcgcacc ctgctcggtg ccttcctgtt caccggggag cagctcgacc
    20041 agcctgcggg cacactctcc ggcggcgaga agacccggtt ggccttggcg ggactggtgt
    20101 ccagcgccgc caacgtgctg ctgctcgacg agcccaccaa caacctcgat ccggcgagcc
    20161 gggaacaggt cctggaagcg ctacgcacct accagggcgc ggtgatcctc gtgacgcacg
    20221 accccggtgc cgtccaggca ctcgaacccg aacgggtgat tcttctgccg gacggcaccg
    20281 aggatcattg gtcggacgat tatctggagc tggtacagct cgcctgatct acgcgcggtg
    20341 actttcacgg taccccctgg tcagcattga taacgcacag tgcggcaata aacactttgc
    20401 gatgttttcc catgatcgcc tggcattaat gctgttcgtg ttcgatcatt gcggcgacgg
    20461 gggccgcaag gggcccgacc tgctcggacg gaaggcggga caaggtggct gacctgaaga
    20521 agggcgcccg catcaccggc gccgcacggg acaagcttgc gacggatctg aagaagaagt
    20581 acgagaaggg cgcgagcatt cgtgccctgg ccgaatcaac cggtcggtcg tacggcttcg
    20641 ttcatcgggt cctcagcgaa tccggcgtgc agcttcgggg gcgcgggggc gcgacccgaa
    20701 ccaagaagaa gtgatcgagg gaccggggtt cgggcggtgt cgcccggccg agtccccggc
    20761 tcttcccagg aaggacccgc cgcgtcgtgg gcgcggcggt tcgagagagg tcggtgggtg
    20821 acggacgaac cggtggatgc cgacacgctt cgccgtggcg gcctccagct ggcgatcgat
    20881 ggccctcggg cgacgatcac gctggaccga cccgaggtac ggggtgcgca gacgccccgc
    20941 acctgggcgg ccttatcgca gatcgggcga agtctgcccg agaaggtgcg ggtggtggtg
    21001 atcgcgggca ccggccgatc cttctcctcg gggttggatc ggcggttgtt cactgaagag
    21061 ggcttcgacg ggatgccggg gctgccgtcc ttggcggcgg cggactccga ggacgccgat
    21121 gcgaggatcg cggagtacca gacgggattc tcctggctgg ccgatcccga gcggttgacg
    21181 atcgccgcgg tccacggcca cgccgtcggt gcgggtttcc agctcgcatt ggcgtgtgac
    21241 gtgcggatcg tggccgatga tgtgcagttc gccat
//
