LOCUS       NZ_CP014859            23618 bp    DNA     circular CON 20-NOV-2024
DEFINITION  Actinoalloteichus hymeniacidonis strain HPA177 chromosome, complete
            genome.
ACCESSION   NZ_CP014859
VERSION     NZ_CP014859.1
KEYWORDS    RefSeq.
SOURCE      Actinoalloteichus hymeniacidonis
  ORGANISM  Actinoalloteichus hymeniacidonis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Actinoalloteichus.
REFERENCE   1  (bases 1 to 6306386)
  AUTHORS   Schaffert,L., Albersmeier,A., Winkler,A., Kalinowski,J.,
            Zotchev,S.B. and Ruckert,C.
  TITLE     Complete genome sequence of the actinomycete Actinoalloteichus
            hymeniacidonis type strain HPA 177T isolated from a marine sponge
  JOURNAL   Stand Genomic Sci 11, 91 (2016)
   PUBMED   28031775
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6306386)
  AUTHORS   Schaffert,L., Albersmeier,A., Winkler,A., Kalinowski,J., Zotchev,S.
            and Ruckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAR-2016) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Coverage                   :: 159x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001747425.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 01:17:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,434
            CDSs (total)                      :: 5,374
            Genes (coding)                    :: 5,337
            CDSs (with protein)               :: 5,337
            Genes (RNA)                       :: 60
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 37
            CDSs (without protein)            :: 37
            Pseudo Genes (ambiguous residues) :: 0 of 37
            Pseudo Genes (frameshifted)       :: 3 of 37
            Pseudo Genes (incomplete)         :: 34 of 37
            Pseudo Genes (internal stop)      :: 1 of 37
            Pseudo Genes (multiple problems)  :: 1 of 37
            CRISPR Arrays                     :: 13
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:46:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2108880
            Orig. end                         :: 2132498
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP014859.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23618
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="8"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23618
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23618
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13618](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13618
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    281..295
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    complement(682..694)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.33"
                     /tool="antismash"
     misc_feature    complement(1657..1672)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.06"
                     /tool="antismash"
     misc_feature    2577..2592
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.63"
                     /tool="antismash"
     gene            complement(2661..3632)
                     /locus_tag="TL08_RS09710"
                     /old_locus_tag="TL08_09825"
     CDS             complement(2661..3632)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009942457.1"
                     /locus_tag="TL08_RS09710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_09825"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_069848290.1"
                     /transl_table=11
                     /translation="MTDQHATPGRSPHAPLITGGVVPPLCTPLTPDRELDVDSLERLVA
                     HLVTAGVHGLFVGGSTGEAAYLPDALRRQALDVVVGTVAGQLPVLAGVVDMSTPRVVEH
                     ARAAAALGADALVATAPFYSPTHPVEILGHFRTIRAAVDLPLIGYDIPSAVHTKLAAAT
                     VAELAADATLAGLKDSSGDLDGLRDVLELVAGIDGFRVFSGSETVADLGLRCGAAGVVP
                     GLGNVDPHGYVRLYDAAVAGDWDEALRQQRRLHTLFDLIRVAPTDRMGRYSSAIGAFKA
                     ALMLRGVIRYPTTSLPMIPLEAAEIEAVGKHLAAADLPVSTQ"
     misc_feature    complement(2889..2891)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3629..5239)
                     /locus_tag="TL08_RS09715"
                     /old_locus_tag="TL08_09830"
     CDS             complement(3629..5239)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009942465.1"
                     /locus_tag="TL08_RS09715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_09830"
                     /product="MFS transporter"
                     /protein_id="WP_084642815.1"
                     /transl_table=11
                     /translation="MDQQYTRPRWYHQLTRKDWKSFFAAWLGYAMDGFDFVLISLVLTE
                     VADEFGLSTVEAATLISAAFISRWFGGLALGAIGDRYGRRPAMVLSIVLYSVGTFACGL
                     AWGYWPLFVARLVVGMGMAGEYSASATYVIESWPKALRNRASGFLISGFSLGGVLAAQA
                     YRFIVPEFGWRALFLLGLLPIVLALWLRRSLPEAPDWQHQAAQRDDTTKERDFVSVLYG
                     GRTRAINIVLTVAVSLALFWLFAGGATGVLSWLLIAVTIGGLAAFTIQFAGRRSPMMLT
                     LIVVVFCAFLYSWPIQALLPTYLKTDLGYDAAQVSGVLFFAGFGTAVGCCLAGFVGDWL
                     GTRRAYSLTLLASLAFTLPVFAIGGDQLLLLGVLLFCQQALAQGISGILPKLVSGYFDI
                     GTRAGGLGFTYNVGALGGAVAPVLGAQIAERTSLATALGGLAFGLTLIVIILIAVDAPA
                     LVQRWFGDDSAGVDLTVDEAQIAPRLRAAETPGGGAATAVATSEPTTGPPPQSGGAEST
                     AGSPAAESDPDTPDGEPKT"
     misc_feature    complement(5084..5086)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5338..6015
                     /locus_tag="TL08_RS09720"
                     /old_locus_tag="TL08_09835"
     CDS             5338..6015
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011874622.1"
                     /locus_tag="TL08_RS09720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_09835"
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="WP_069848292.1"
                     /transl_table=11
                     /translation="MAENGRRLQDRIIDLIIDRGLAPGEPLPTEGQLVDELGVGRNSVR
                     ESLRALSTLGIVDIRHGYGTFVGAAPITAFTPGLLFRTRQSMQQDASVLRDLVEIRRVL
                     EMSLIETVVDRADEDLVGELDDLVAAMESGDLVETDQRFHETLFRPLNNGIALELIGLF
                     WTVYHRVETELDPPGPERAEICSEHRAIVEAVRAGDPVAARSALGAHFVDIEQRVARLG
                     DPR"
     misc_feature    complement(5370..5385)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.34"
                     /tool="antismash"
     gene            complement(6048..6575)
                     /gene="lspA"
                     /locus_tag="TL08_RS09725"
                     /old_locus_tag="TL08_09840"
     CDS             complement(6048..6575)
                     /EC_number="3.4.23.36"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="lspA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005438219.1"
                     /locus_tag="TL08_RS09725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_09840"
                     /product="signal peptidase II"
                     /protein_id="WP_216637810.1"
                     /transl_table=11
                     /translation="MTAESDVEPPAAGPAERTPTESTPRATRIRATLLAVAVVLAAVDL
                     IVKHLVEQAHPAGPDFGFLSVRLSYNPGIAFSLGDTLPAWVVIALTSAVTLGITLYALH
                     TAPEVPTAARAGMSMILAGAAGNLIDRIADGAVTDYLYTGWFPTFNLADSLLTCGVVLL
                     IASTLRAESRAD"
     misc_feature    complement(6267..6269)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6604..7299)
                     /locus_tag="TL08_RS09730"
                     /old_locus_tag="TL08_09845"
     CDS             complement(6604..7299)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013933.5"
                     /locus_tag="TL08_RS09730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_09845"
                     /product="LysE family translocator"
                     /protein_id="WP_069853511.1"
                     /transl_table=11
                     /translation="MPEGIPLFIAITALTIVVPGPDFVLVTRNTLLLGRRAGYLTAAGI
                     SIGLTVYTLLAVLGLTALIAAQDGMLTALKLAGGGYLVFLGWRGLRSWWRSRRAAGTDV
                     AAVLAQGPAPLDTAPLDTATDEPTRAGLRGGGPLAQGVLNNLLNPKALVFYVTLLPQFI
                     TPGDRIVEQTLLLSTTATLLAVLWWFLFVTAVDRVTPILRRRRVRDGLDLGTAVLLGGF
                     GIAVAAGAL"
     gene            7408..7890
                     /locus_tag="TL08_RS09735"
                     /old_locus_tag="TL08_09850"
     CDS             7408..7890
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004560419.1"
                     /locus_tag="TL08_RS09735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_09850"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_069848293.1"
                     /transl_table=11
                     /translation="MTTSVELDSIDLEILRLLQKDARITNKELASAVRVAPSTCLDRVA
                     RLRSTGVILGQTIRIDPERLGRPLDALIALRIQPHRRELCDPFAAHTLALPETRALYNL
                     AGPDDFLVHVSTSGATDLHRLVLDEFASREEVSHINTTLIFQQWVGGPLLPPTAPR"
     misc_feature    complement(7426..7439)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.17"
                     /tool="antismash"
     misc_feature    7456..7458
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    7630..7632
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7985..8542
                     /locus_tag="TL08_RS09740"
                     /old_locus_tag="TL08_09855"
     CDS             7985..8542
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203: putative siderophore biosynthesis protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007023451.1"
                     /locus_tag="TL08_RS09740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_09855"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_069848295.1"
                     /transl_table=11
                     /translation="MATSEVGPPPLPEVTGPWAVRDLRPEGADLTLLHEWMNREHVAAF
                     WHQDWSRQRWIEELTTQAAGDHSRPVLLSHEGAPLAYLEVYRVIRDRLAACYPVRPHDL
                     GVHVAIGELQATGRGLGRALLREVALGLLRADPACDRVVAEPDISNAPSVRAFEAAGFH
                     NHGRITLSDKTAALLIHPRAAG"
     gene            complement(8566..9318)
                     /locus_tag="TL08_RS09745"
                     /old_locus_tag="TL08_09860"
     CDS             complement(8566..9318)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016700253.1"
                     /locus_tag="TL08_RS09745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_09860"
                     /product="rRNA methyltransferase"
                     /protein_id="WP_069848297.1"
                     /transl_table=11
                     /translation="MPYRFAVEQTDHADLAGGAVLRSAPGLPAFPVRLATELFARAAAR
                     LPGGAELTMWDPLCGSGYLLTVLGLLHRGELGAVLGSDVDERATEVATANLALLTSAGL
                     RARAGRLHEQAAEFDKPAYALAAEAAGRLAGLLLAGGGDLRAEVRRADALDPDALGGVV
                     EGFPPVDLVLADLPYGEQTRWRGEHGAAAEPQARLLRALRPNLPDHAVLVLVDRSRKVV
                     LPAGLRPLERFRIGTRSAVLLRAADLPT"
     gene            complement(9443..9799)
                     /locus_tag="TL08_RS09750"
                     /old_locus_tag="TL08_09865"
     CDS             complement(9443..9799)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="TL08_RS09750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="TL08_09865"
                     /product="hypothetical protein"
                     /protein_id="WP_157421015.1"
                     /transl_table=11
                     /translation="MERRIDLDNLDLDQAALLVDQRRRRWSAAGITVARITWMDAHDGW
                     PRPLYENRRLVRRPMSLGLELDGTGGSAWIVLYAGGWADVDLMVGDADPVAEYVEPATV
                     AEFGPLLDRVSDRL"
     gene            10001..11167
                     /locus_tag="TL08_RS09755"
                     /old_locus_tag="TL08_09870"
     CDS             10001..11167
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005445899.1"
                     /locus_tag="TL08_RS09755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_09870"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_084642818.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.7e-49, bitscore:
                     164.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTGDHVATVVRPGSPNGSGLPGPGLQAADVEVVRAVDAHLAEY
                     LAQRRAEAVAVDDHFTVELVDPLISFVREGGKRLRPLFAWWGWRAAGGADAGAEADAVL
                     RAVSAVELVHACALVHDDVMDDSAIRRGKPAVHVAMAARHRAAGMRGDDVGFGRSMAIL
                     VGDLALCWADDMMHTSGASQAMLHRAGSAWRAMRTEMMAGQFLDLRAQATGTESIESAL
                     RVNLLKTAGYTVAQPLLLGALLGGASSELSAALHAYGVDLGTAFQLRDDFLGVFGEPEI
                     TGKPAGDDIREGKHTVLVNEALRLTELHGRPDEAATLRGALGDPLLSPQTLAEVRRVLV
                     DSGAVAVVEQRIETLAISAVDRLSGVDLSESTAARLRTLADAMIRRDV"
     gene            11160..12695
                     /gene="crtI"
                     /locus_tag="TL08_RS09760"
                     /old_locus_tag="TL08_09875"
     CDS             11160..12695
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800241.1"
                     /locus_tag="TL08_RS09760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_09875"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_069848301.1"
                     /sec_met_domain="DAO (E-value: 1.3e-15, bitscore: 56.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDPLARRWSGALRTGRGMTGRTDHVVVVGAGLAGLSATLHLLGA
                     GRRVTVVEAGPRPGGRAGLAETAGYRVDTGPTVLTMPEIIADALDAVGESLTDRLDLLP
                     LHPAYRAAFADGSTVAVHTDAERMEAEIRRFAGPVEAQGYRRLRRWLTELYTAQYDRFI
                     AANIDSPSDLVHPAAARLVALGGLGRLGPAVERRIGDERLRRVFSFQALYAGLAPHRAR
                     AAYGVIAYMDTVGGVYFPRGGMHAVPRALAAAATAHGAEFHYDAPVRRLERTGDRIRAV
                     HTDQGRIECDAVVLTPDLPETYRLLGRTPRRPVPLRWSPSAVVLHLGVARGAAMQTDHH
                     VISFGSAWRRTFAEIIDEGRLMSDPSLLITRPTRSDPGLAPPGRELLSVLAPAPNLAVG
                     RQDWARMGTAYRDELLAVLTDRGLLDAAPDIDLSELVTPRDWAAQGLGAGTPFSLAHTV
                     AQTGPFRPANLVSGIANAALAGSGTTPGVGVPTALISGKLAAARVTGAMAGRG"
     gene            12692..13618
                     /locus_tag="TL08_RS09765"
                     /old_locus_tag="TL08_09880"
     CDS             12692..13618
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009942167.1"
                     /locus_tag="TL08_RS09765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_09880"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_069848303.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.3e-112,
                     bitscore: 373.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.3e-61,
                     bitscore: 206.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPGELDAAGIEGTALRRSYLRCRALHARFGRTYFLATRLLRPEQ
                     RPAVHALYGFARWVDDIVDEPGGEDPAPRLDRVADRVAADLHATHSTHAVLAALVDTVR
                     RYGIDHRLFTDFLTSMRMDLTVTEYPSDRELAGYIRGSAEVIGLQLLPVLGTVVADDVA
                     AEHAAALGAAFQLTNFLRDVGQDLDRGRIYLPMDELATFGVDRELLRWCRRTGRTEPRL
                     RRAVAHFIARNRAVYRRALPGIPMLAPVARPCVTTAAVLYQGILSEIEAADFDVVSRRA
                     VVPRRRRLAVVVPTLAHSIALRMTAAR"
     gene            13880..14827
                     /locus_tag="TL08_RS09770"
                     /old_locus_tag="TL08_09885"
     CDS             13880..14827
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012376.5"
                     /locus_tag="TL08_RS09770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_09885"
                     /product="metallophosphoesterase"
                     /protein_id="WP_069848305.1"
                     /transl_table=11
                     /translation="MPSTKAVALGAAFSTLIATGLAVAPVAAQAQPDQSDSQGTIAWIS
                     DTQYYSQRYPDIFTGMTEWVASEADSRGIEYLAHTGDIVEYYPFTREWDNASASMGVLE
                     DAGIPYGVAAGNHDVATFWSGYTITDYGVFSEYFGEDRFADSPVYGESFKDNRQHYDLV
                     TIGGVEFVVLYLAWRLDAADIAWASEVLTEHADKPAIIGVHEYIDAQGEYSGRGEQIFD
                     ELVEPHDNVSLVISGHIHGAATNVVELDGDRRVVEMLADYQDAPQGGSGYLRLLTVDTA
                     ASTLQVQTYSPHLDSTGYFDDAVENTTLPLDITP"
     gene            15101..16288
                     /locus_tag="TL08_RS09775"
                     /old_locus_tag="TL08_09890"
     CDS             15101..16288
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018018.5"
                     /locus_tag="TL08_RS09775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_09890"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_069848307.1"
                     /transl_table=11
                     /translation="MGFTRASLTALVAALVLPWCSGSVTGPEPAEPLPGAVAWSRHRVD
                     GEALPDAEQAEPQTVADFLTDAGRQNTDELVERFPFVMGNLDGAPLRTRFAANRRAIAL
                     ERARLAAVAADQSLSEPARSSARRTEAMYRRLAENRRPVLLFDPRGRGRYAEVHGDLAN
                     ATHVAVVVPGTGISTRSFDPRSGHVGTPGAMAAELYRTQRALSPAASTAVVAWAGYATP
                     QALGVGAATARYAEAGAEELRDLIDGLIAARSSPDAGHPTRSTTRVTLLCHSYGSVVCG
                     RAAEKLPEAVHDIVVFGSPGMGVDTVTELHTDARLWAALGPSDWIRHVPNVRFLGFGHG
                     RAPTSAAFGARRIPATDVRGHDGYLHRDTDTARRFAQISLDLVSEPHHTGADTHR"
     misc_feature    15122..15124
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    15824..15826
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16285..17625
                     /locus_tag="TL08_RS09780"
                     /old_locus_tag="TL08_09895"
     CDS             16285..17625
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013884.5"
                     /locus_tag="TL08_RS09780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_09895"
                     /product="acyltransferase"
                     /protein_id="WP_084642820.1"
                     /transl_table=11
                     /translation="MTSTDSTAVPRRTRRGRVPEPRHARRGLSARLRAIDDATPAERDR
                     VIDALRALAIVGVVLGHWLVSVVVFDQNGPHIASPLQHLPELTPLTWVLQLLGLFFFAG
                     GWANVRSLDRASGGSASATTRGSILGRGYLPWLGARLDRMLRPVVLLAGFVAVLLAVLG
                     LSGWTGADLYTVGLFVVSPLWFLPVYLVLTAGTPIVDAAVRRWGAWAAVGPAAVVLLLD
                     LLRYGPWWELPASVGTPNLIAAWLVPYVLGVAFARGRLVQAAGPWLFVAGLAACVALIV
                     FADYPASMTGVTGADRSNMGPPSLLVPAMALAQLGVALTFYRRLARALTRPWLWAIVVT
                     INLVAMTVYLWHQTALMSTQLATHAVGLSLLGFDGVPADLTWLLSRLALLPLCGVVLCG
                     FILLFRRWEQRSASTVLRPAAPAGATADAARPTAADQDPPRHTSPAG"
     misc_feature    16570..16572
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17589..18887)
                     /locus_tag="TL08_RS09785"
                     /old_locus_tag="TL08_09900"
     CDS             complement(17589..18887)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1268: mandelate racemase/muconate lactonizing enzyme"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003070035.1"
                     /locus_tag="TL08_RS09785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_09900"
                     /product="L-fuconate dehydratase"
                     /protein_id="WP_069848309.1"
                     /transl_table=11
                     /translation="MSRIVALEVSDVRFPTSRELDGSDAMNPDPDYSAAYLVLRTDEGP
                     DGHGFVFTIGRGNDVQCAAIELLAPHVVGRDVEKLCADLGGLSRELVSDSQLRWLGPEK
                     GVMHMAVGAVVNAAWDLAAKRAGMPVWRLLASLTPEQIVELVDWRYLTDALTPDEALEI
                     LRAAEPGRSERLQRLEREGYPGYTTSPGWLGYDDAKLARLATEAVAEGFDLIKLKVGAA
                     LDDDVRRLGVARAAVGPDVRIAIDANQRFDVDTAIPWLRRLREFNPWWIEEPTSPDDVL
                     GHAAIRNAVAPMRVATGEHVQNRVMFKQLLQAGAIDILQIDATRVGGVNENVAILLLAA
                     KFGVPVCPHAGGVGLCELVQHLAMFDYVAVSGALDGRAIEYVDHLHEHFSTPVRIRDGR
                     YQVPIDPGSGAEMLADSRQRFAYPAGEVWRGGS"
     gene            complement(18884..19750)
                     /locus_tag="TL08_RS09790"
                     /old_locus_tag="TL08_09905"
     CDS             complement(18884..19750)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005462720.1"
                     /locus_tag="TL08_RS09790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_09905"
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="WP_069853514.1"
                     /transl_table=11
                     /translation="MRLLRLGAPGAERPALRTDDGAFFDLSPITDDIDGAFLAAEGIDR
                     ARTALAAGTLPALDPTGLRIGAPIARPMAVLCIGQNYAAHARESGAEPPAQPILFFKHP
                     NTIVGPDDAVRIPPGSSRTDWEVELAVVIGKRASRLAGPEDAAAHIAGYTVSNDISERE
                     WQLERSGGQWSLGKCGPGFNPLGPWLVPAEDIGDPQSLRLRSWVNGAPRQDSATSDMVF
                     DVAFLVWHLSRFLTLEPGDVINTGTPEGVALSGRFPYLGAGDVVELEIDGLGRQRQVMT
                     GPEGEAA"
     misc_feature    complement(19562..19564)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(19839..20543)
                     /locus_tag="TL08_RS09795"
                     /old_locus_tag="TL08_09910"
     CDS             complement(19839..20543)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019349.5"
                     /locus_tag="TL08_RS09795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_09910"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_069848310.1"
                     /transl_table=11
                     /translation="MNAAPRGSGSTTARAPSAPRRSVLVDEVYETIKNLIMDHAIAPGE
                     RLSIDGLARRLEVSPTPVREALARLESTELVVKEPLRGYRTTALLTLEQLDDLYRFRLL
                     LEPWAAAEAARGATEPAKDRLRAELDSCAPPDSQRYQALALHDTRFHLLIAELSGSAQI
                     RRAFEQTHCHLHIFRLYYDQRIATMALAEHRRVTEAVVAGDPVAAKLAMRAHLEASYYE
                     RLRPLFDTGNPP"
     gene            complement(20786..21070)
                     /locus_tag="TL08_RS09800"
                     /old_locus_tag="TL08_09915"
     CDS             complement(20786..21070)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="TL08_RS09800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="TL08_09915"
                     /product="hypothetical protein"
                     /protein_id="WP_157421016.1"
                     /transl_table=11
                     /translation="MNDGFLRNLVRALARNTPAFTPPRPVYADRRPGLRAALARDVAEQ
                     AERHAPDDRLDRRSDGDTHAESAGGRRRDSAASINRSPDGRRRPLTASG"
     gene            complement(21063..21500)
                     /locus_tag="TL08_RS09805"
                     /old_locus_tag="TL08_09920"
     CDS             complement(21063..21500)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="TL08_RS09805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="TL08_09920"
                     /product="hypothetical protein"
                     /protein_id="WP_069848313.1"
                     /transl_table=11
                     /translation="MVGWEYALWGLFGGFAVEGLEFSGAIRRTGTWPWRVPDEPGPLPL
                     LVSVLIRLGVGSGLAAAAGIAGQVSGPFGALAIGVAAPLLVEQLTRALPAADASRPPQA
                     PEGPQRRDIAWRDTDAERIRSVEQAPRPAPAVSPHSGGADE"
     misc_feature    complement(21639..21653)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.98"
                     /tool="antismash"
     misc_feature    21759..21773
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.28"
                     /tool="antismash"
     gene            21886..22311
                     /locus_tag="TL08_RS09810"
                     /old_locus_tag="TL08_09925"
     CDS             21886..22311
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005460457.1"
                     /locus_tag="TL08_RS09810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="TL08_09925"
                     /product="YciI family protein"
                     /protein_id="WP_069848315.1"
                     /transl_table=11
                     /translation="MRFMVLVKSDADTEAGVLPSEELLTAMGRYNEELVAAGVLLAGEG
                     LQASQNGARVQWNDGAAPTVVDGPFAEAKELVAGFWILQVKSKAEAIEWAKRCPAPEQG
                     EQVLEVRQIFEMDDFGDAATPEVRESAEALRSKTEKK"
ORIGIN
        1 gggtcgtccg aggtgaactg ggcgtcgctg accaccgcga cccgcagggc accccgctcg
       61 gcgtccagcg cgtcgtcgac caccaccgac gtgtcggggc gtaccggttc ggcgggcacc
      121 tcggcgatag gcgagaccga ggcggtgaga tcgtcgaaga cgacccgacc ctcgtactga
      181 tggtcgcgat cggtctcgac caggtagaag cggtgcagcc gcagcggtgc ggcgagcccg
      241 gcggggacgt cggtctcgac gtaacgccac cccgtccagt cgaccgagtc ggccagactc
      301 agcacggcgg gggatcccgc cgcatcgcgc agctccagtc gcagccaggc gcccgcgcca
      361 tcgccatcga cccacagccc gatgcgttgc gtaccggcgg gcagttcccg ctggggtacg
      421 gcgttgacgt aggcggcgcg ggtggcggtg gtcccggtga gccggtagtc cagcgcgatc
      481 ccctggccgc cctcgcggcc gtcggcctgc gagacggccg atcccacgac cgaggggaag
      541 gcggtggcct gccagccctc caccccgtcc aacgggtcca cgatccgcgc ctcggtgccg
      601 accgaaaccc cgacccgtgc ggtgagtccg gccgcggtcg cggtgatcgt ggtcgacccg
      661 gtgtcgacca gggcggtcac ggtgagaccg tcaccgttcg gctcgacccg caccacctcg
      721 gggtcgtagt cgagttcgag gtcggcgggc tcgacccagg tgctgaagcc gtccgcgtcg
      781 ttgccgagga cgcgcagcga gctggagaca tcggcgtcgg acagcatcac ctgtccgacg
      841 tcggcccgga gccggaccgg cgcgcccagc acgtccagct cgacatcacc ccggactcga
      901 ccggaggtgg ccgtgacgac cgtccgaccg acccggtccg cgcggtcggt ggcgtggaag
      961 atcccgtcgc ctcggatgcg tccgtgcctc gggcgatcca ccgaccagcg gtgtgccgcc
     1021 tcgaccgagg cgccgctctc gtcgtggccc aaggcctgca accgtctgct cagccccgcg
     1081 agcacccgct gggagtccgg acccgctgtc gccggttcgg cgcggaaacc ggtcagtctg
     1141 ccgctgccgg gcgcggtgcg cagccccaat ccgttgggca ccaaccgctg cccgccgtcc
     1201 gacggcgaat tatggaccgt cggtgcggcc tcgcccgcct tgcgggccag cagcgtcgac
     1261 gagccgccgc cgtcgaggtt gagcgcgtcg tgggcaccga gggaacgcag ctgatgggcc
     1321 agttccaact cggtcatgcc tcggctggcc gactgcctgc cgtcgatggt gaccagccag
     1381 aaccgcgatc cgtcctcgga gaatccgacg gcggtccggg gatgcgcggt cacgttgtcg
     1441 accggctgga cctcgccgtc gacgatcagc gcccggttgc cgccgacggc caccgcgatg
     1501 tcggcgatgt cctcggagtc ggtgcgtgga gccaggctca ccccgacggc atcgccttcc
     1561 gcgaggtcgg cgagcgcccg ggccccggca tcacgggcca gcagcacctg ggtgccctcg
     1621 gcgatcgggc cgtcgccggg tgcggtgcgg atggcggtga ccagtccgtc caccaactcg
     1681 acctcgagta cctcggtggc acccgccgtc gcggtgagtc gactcgccga gccccattcg
     1741 ggggtgaaca ccccgatgcc gtcggcggcg atcaccggcg agttcaggtt gtcggcgggc
     1801 aggacgtcgc cgccgggcag ggtgaggtgc gcttcgagga acacctcggt gagcgcggcg
     1861 cggtggtcct cggtgaaggt cgcggccagg ttgtgtccgg cggcgggtgc gtgccgcagt
     1921 tccccgtcgt cgatgccgac gcccaggggg gcgccggtcg cgttgatgtc gaagaagtcg
     1981 ccgttgaccc cggcgaccgc gtcgaccctg gccagctgtt cggacagcgg ggttcgcgcc
     2041 gagaccgtgc cggggtgcag gtaggtcggt tccaggcccg ccgtggacaa ctcggcgctg
     2101 agcacgtcac cccggatcca gccctgcggg tcgaatcgat cgaactcggt gagttccact
     2161 ccgggggcca ccagggtggt ggtgctgtcg gtggtgagcc ccggatgcgg cgtcgcggcc
     2221 gggtcgatcg aggtccgcag cgcctgttcc gaggccgatg acgcggcggg cgagtcctcg
     2281 acgggtcgag gcccggccgg aaccccggtg tcggcgccct gcgcgcccgc gccggtgccc
     2341 gccgcgagca gcagcatcgc cgctgccgtc gcgatcccgg ccgtgcgggc gagccgactc
     2401 ggccgggatc gctgcggttc cgacgtgccc gtcggtgctg ttcgtcgtgt cgtccatccg
     2461 ttgatccgcc gtcgcacggc cgccccctgg cacactcgta tccggtggtg agcccgccga
     2521 gcacagccca tccagccggc cgagggctgt cccggacatg acaggggcgg gaactcttga
     2581 cgatctcgtc caccagcctg gcgaaccgga cgacacgcct gccgcgcccg aaagggtgat
     2641 agtcgggcgc gttcggcggt ctactgtgta cttaccggca gatctgcggc cgccaggtgc
     2701 ttgccgacgg cctcgatctc cgccgcctcc agcgggatca tcggcaggct cgtggtcgga
     2761 taccggatga cgccgcgcag catcaacgcc gccttgaacg ccccgatggc cgaggagtac
     2821 cggcccatcc gatcggtcgg cgccaccctg atcaggtcga acagggtgtg cagtcggcgt
     2881 tgctgccgta aggcctcgtc ccagtcgcct gccaccgccg cgtcgtacag ccggacgtag
     2941 ccgtgcggat cgacattgcc cagtccgggg accacgccgg cggcgccgca gcgcaatccg
     3001 aggtcggcca cggtctccga gccgctgaac acccggaaac cgtcgatccc cgcgaccagt
     3061 tcgaggacat cgcgcaaccc gtcgaggtcc ccgctggagt ccttcagccc ggccagggtc
     3121 gcgtcggcgg ccagctcggc cacggtcgcg gcggccagtt tggtgtggac ggcgctgggg
     3181 atgtcgtagc cgatcagcgg cagatcgacg gcggcgcgga tggtccggaa atgcccgagg
     3241 atctcgacgg gatgggtggg ggagtagaac ggcgcggtcg cgaccagggc gtcggcaccc
     3301 agggcagccg cagccctggc gtgctccacg acccgagggg tggacatgtc gacgacgccc
     3361 gccagcaccg gcagttggcc cgcgacggtg ccgaccacga cgtcgagggc ctgtcgacgc
     3421 agcgcatcgg gcagataggc ggcctcgccg gtcgagccgc cgacgaacag cccgtgcacc
     3481 ccggcggtca ccagatgcgc gacgagacgt tcgagcgagt cgacgtcgag ttcccgatcg
     3541 ggggtcagcg gggtgcacag cggtggcacc acaccgcccg tgatgagcgg cgcgtgcggc
     3601 gatcgtcctg gtgtggcgtg ctggtcggtc atgtcttcgg ctctccatcg ggagtgtcgg
     3661 gatcggactc tgcggcgggg gatccggctg tgctctccgc gcccccggac tgcggtggtg
     3721 ggccggtcgt cggctcggag gtggccacgg cagtggccgc gccgcctccg ggggtctcgg
     3781 ctgcccgcag cctgggggcg atctgggcct cgtcgaccgt gaggtcgacc ccggccgagt
     3841 cgtcgccgaa ccaccgttgc accagggctg gcgcgtccac ggcgatcagg atgatcacga
     3901 tcagggtgag accgaaggcc aacccgccca acgcggtcgc gaggctggtc cgttcggcga
     3961 tctgcgcacc gaggaccggt gccacggcgc cgcccagcgc tcccacgttg taggtgaaac
     4021 cgaggccgcc cgcccgggta ccgatgtcga agtagccgga gaccagcttc ggcaggattc
     4081 cggagattcc ctgggccagg gcctgctggc agaacagcag gacgccgaga agcagcagtt
     4141 ggtcgccgcc gatcgcgaac accggcaacg tgaaggccag cgaggcgagc agcgtcaggc
     4201 tgtaggcacg tcgggtgccc aaccagtcgc cgacgaagcc cgcgagacag cagccgacgg
     4261 cggtgccgaa gcccgcgaag aacaacactc cgctgacctg tgcggcgtcg tagccgaggt
     4321 cggtcttcag ataggtcggc agtagcgcct ggatgggcca cgagtagagg aaggcgcaga
     4381 acaccaccac gatcaaggtc agcatcatcg gactgcgcct gcccgcgaac tggatggtga
     4441 aggcggccag tccgccgatc gtcaccgcga tcaacaacca ggacagcaca ccggtcgcgc
     4501 cgcccgcgaa caaccagaac agggccagcg acacggcgac cgtgagcacg atgttgatcg
     4561 cccgggtgcg cccgccgtag aggacgctga cgaagtcgcg ctccttggtg gtgtcgtcgc
     4621 gctgtgcggc ctggtgctgc cagtcgggtg cctccggcag gctgcggcgc agccacagtg
     4681 ccagcacgat cggcagcaga ccgagcagga agagcgcgcg ccagccgaac tcgggaacga
     4741 tgaatcggta ggcctgggcg gcgagcactc cgccgaggga gaagccggag atgaggaatc
     4801 cgctggcccg attgcgcagt gccttcggcc agctctcgat cacgtaggtg gcgctcgcgc
     4861 tgtactcgcc cgccatgccc atgccgacga ccagcctggc cacgaacagc ggccagtagc
     4921 cccaggcgag gccgcaggcg aaggtgccga cggagtagag cacgatgctc agcaccatcg
     4981 cgggccgccg tccatagcgg tcgccgatcg cgccgagcgc caacccgccg aaccagcggg
     5041 agatgaacgc cgcggagatc agggtggccg cctcgacggt ggataagccg aactcgtcgg
     5101 cgacctcggt cagcaccagc gagatgagga cgaagtcgaa gccgtccatc gcgtaaccga
     5161 gccacgcggc gaagaacgac ttccagtcct tcctggtgag ctggtgatac caccgaggtc
     5221 gggtgtactg ctggtccatc agagcctcct tgctccgctg gcagacatcc cacctgggag
     5281 gtgggatgtc ttggcaaggt acggttggta cccacaccgt ggcaagaggg atggtcagtg
     5341 gcagagaacg gtcggcgcct tcaggaccgg atcatcgatc tcatcatcga ccgagggctc
     5401 gcccccggcg aaccgttgcc caccgagggg cagctcgtcg acgaactggg tgtcggccga
     5461 aactcggtgc gggaatcgct gcgtgcgttg agcaccctgg gcatcgtcga catcagacac
     5521 ggttacggga ccttcgtcgg cgcggccccg atcaccgcct tcaccccggg tctgctgttc
     5581 cggacccggc agtcgatgca gcaggacgcg tcggtgctcc gcgacctggt ggagatccgc
     5641 cgcgtgctgg agatgtcgct gatcgagacc gtggtcgacc gggccgacga ggacctggtg
     5701 ggcgagctgg acgacctggt cgccgcgatg gagtcggggg atctcgtcga gaccgatcaa
     5761 cggttccacg agaccctgtt ccggccgttg aacaacggga tcgccctgga actcatcggc
     5821 ctgttctgga ccgtctacca ccgggtggag accgaactcg acccgccggg gcccgagcgg
     5881 gcggagatct gctccgagca ccgggcgatc gtcgaagccg ttcgagcggg cgatccggtg
     5941 gcggcccgat cggccctggg tgcccacttc gtcgacatcg agcagcgggt cgcgcggctc
     6001 ggcgatccgc gctgagctcg gcggcagtgg gccgggaacg tcgcggatca gtcggcgcgg
     6061 gactcggcgc gcagcgtcga ggcgatcaac agcacgaccc cgcaggtcag caggctgtcg
     6121 gcgaggttga aggtgggaaa ccaccccgtg tacaggtagt cggttaccgc gccgtcggcg
     6181 atccggtcga tcagattgcc cgcggctccg gcgaggatca tcgacatgcc cgcccgagcc
     6241 gccgtgggca cctcgggtgc ggtgtgtaac gcatagagcg tgatcccgag ggtgaccgcg
     6301 ctcgtcaggg cgatgaccac ccaggcaggc agggtgtcgc cgaggctgaa ggcgattccc
     6361 gggttgtagg acagtcgcac actgaggaat ccgaagtcgg gacctgcggg atgcgcctgc
     6421 tcgaccaggt gcttgacgat caggtcgacc gctgccagca cgacggcgac ggccaacagc
     6481 gtggcccgga ttcgagtggc cctcggtgtg gactccgtcg gggttcgctc ggcggggcct
     6541 gcggcgggcg gttcgacgtc ggattcggcg gtcaccaccc agacattacc gatcgggcgg
     6601 ggttcacagg gcgcccgccg cgacggcgat gccgaagccg cccagcagca cggcggttcc
     6661 gaggtcgagc ccgtcccgca ccctgcgtcg acgcaggatc ggggtcaccc ggtcgacggc
     6721 cgtgacgaac aggaaccacc agagcaccgc cagcagggtc gccgtggtgc tcaacaacag
     6781 cgtctgctcg acgattcggt cgcccggagt gatgaactgc ggaagcaggg tgacgtagaa
     6841 gaccaaggcc ttgggattga gcagattgtt cagcaccccc tgcgccaacg gtccgccgcc
     6901 gcgcaggccc gcgcgggtgg gctcgtccgt ggcggtgtcg agtggggcgg tgtcgagtgg
     6961 ggcggggccc tgcgcgagga cggccgcgac atcggtgccc gccgccctcc tgctgcgcca
     7021 ccaggaccgc agaccgcgcc aaccgaggaa gaccaggtag ccgccgcctg cgagtttcag
     7081 cgcggtcagc atcccgtcct gggcggcgat cagagcggtc agtccgagca cggcgagcag
     7141 cgtgtacacg gtgaggccga tgctgatccc ggcggcggtg agataccccg cacgacggcc
     7201 cagcagcagg gtgttccggg tgaccaggac gaagtccgga ccggggacca cgatggtgag
     7261 cgccgtgatc gcgatgaaca gtggaatgcc ttcgggcacg tcgaattctc tctccggtcg
     7321 agcgctgctg tcgccggaca cgaggcgacg ggaggattct gcaaccacat ccggggatcc
     7381 ggcgagaagt tcgtttaata ttcgacgatg acgacctccg tcgaattgga ttcgatcgac
     7441 ctggagatcc tgcggttact gcagaaggac gcacggatca cgaacaagga gctggcctcg
     7501 gcggtccggg tcgccccgtc gacctgtctg gaccgcgtcg cccgactgcg ctcgaccggg
     7561 gtgatcctcg ggcagacgat ccgcatcgac ccggaacggc tgggcagacc gctggacgcg
     7621 ttgatcgcct tacgcatcca gccgcatcgc cgcgagctgt gcgacccctt cgccgcccac
     7681 acgctggccc ttcccgagac cagggcgctc tacaacctgg cgggcccgga cgacttcctg
     7741 gtgcatgtct ccacctcggg cgcgaccgat ctgcaccggc tggtgctcga cgagttcgcc
     7801 tcccgcgagg aggtctccca catcaacacc accctgatct tccaacagtg ggtgggcggt
     7861 ccgttgctcc cgcccaccgc gccgaggtga cacaactcgt gttccgcgcg atgaagatcg
     7921 tgggatcgtt gcatcgggac ggccgtgcga aggccggtcg atcggacgag ggagtcgatg
     7981 ccggatggcc acgagcgagg tgggaccgcc gccgcttccc gaggtgaccg gcccgtgggc
     8041 ggtgcgcgac ctccgacccg agggcgccga tctgaccctg ctgcacgagt ggatgaaccg
     8101 cgagcacgtg gcggcgttct ggcatcagga ctggtcacgg cagcggtgga tcgaggaact
     8161 gacgacccag gcggccggtg atcattcccg gccggtgctg ctgtcccacg agggggcgcc
     8221 gctggcgtac ctggaggtct accgggtgat ccgggaccga ctcgccgcct gctacccggt
     8281 gcggccccac gacctcgggg tccatgtcgc gatcggggaa ctccaggcga ccgggcgtgg
     8341 gctgggccgg gcgctgctcc gggaggtcgc gctcggtctg ctccgagccg acccggcctg
     8401 tgatcgggtg gtggccgaac ccgacatctc caacgcgccg tcggtccgcg ccttcgaggc
     8461 ggccggtttc cacaaccacg gccggatcac cctgtccgac aagaccgccg cgttgctcat
     8521 ccaccccagg gcggccgggt gaccctgcga gcgccgaggc gcgactcagg tgggtaggtc
     8581 ggcggcccgc aacagcacgg ccgatcgagt gccgatccgg aagcgttcca acggccgcaa
     8641 accggcgggc agtaccacct tgcgcgatcg atcgaccagc accagcacgg cgtgatcggg
     8701 cagattcggc cgcagtgctc tcaacagccg tgcctgcggc tcggccgcag cgccgtgctc
     8761 gcctcgccaa cgggtctgct cgccataggg caggtcggcc agcaccaggt cgaccggcgg
     8821 gaagccctcg acgaccccgc cgagcgcatc gggatccagc gcgtccgccc gccggacctc
     8881 ggcacgcaga tcgccgcccc cggctagcag taggcccgcc agtcggcctg ctgcctcggc
     8941 ggcgagcgcg tacgcgggct tgtcgaactc ggcggcctgc tcgtgcagcc gccccgcgcg
     9001 ggcccgcagc ccggccgagg tgagcagtgc cagattcgcc gtcgccacct cggtggcccg
     9061 ttcgtcgacg tccgagccca ggacggcgcc cagctcgcct cggtgcaaca gacccaggac
     9121 cgtcaacaga tatccgctgc cacacagcgg gtcccacatc gtcagctcgg cgcccccggg
     9181 cagccgcgcg gccgccctgg cgaacagctc ggtggccagt cggaccggga aggcaggcag
     9241 tccgggggcc gaccgcagta ccgcgccgcc cgccagatcg gcatgatcgg tctgctcgac
     9301 ggcgaatcgg tacggcacgg gagcctctcc ccacgacgac ggccgacggc gaaccctgcc
     9361 gacggcaatg gcccagccta ggacaacgac ccgaggcggg gtcggctcgg gcgagagcga
     9421 acccgaggtg gcacccggtc gctcacagcc ggtcgctcac ccggtccaac agcggtccga
     9481 actccgccac ggtagccggc tcgacgtact ccgcgaccgg gtcggcgtcc ccgaccatca
     9541 ggtccacgtc cgcccagccg cccgcgtaga gcacgatcca cgccgaccca ccggtgccgt
     9601 ccagttccag cccgagcgac atcggccgcc ggaccaggcg gcgattctcg tacagcggtc
     9661 ggggccaccc gtcgtgggcg tccatccagg tgatccgcgc gacggtgatc ccagcggcag
     9721 accaccgcct gcgacgctgg tcgaccaaca gcgccgcttg gtcgaggtct aggttgtcca
     9781 gatctatccg ccgctccacc tgcacggacg gtaatggccg ttggcgccgt cgaccagtgc
     9841 ccgtccgcgt acgccggttc gcccgcctcg cgtgcccaac cccgacaccg gggggtgtgc
     9901 tctccgatgg tttcgcgccg gctagcgtct tgaagaccac gtcggcgtcc gctgcccagc
     9961 ggtccgtgcc gacaaccccc aggcaacgag gagacgtggc atgactcgaa ccggcgacca
    10021 cgtcgcgacc gtggtccgtc ccggcagccc caacgggtcc ggcctgcccg gtcccggcct
    10081 gcaggcggcc gacgtcgagg tggtgcgggc ggtggacgcc catctggccg agtacctggc
    10141 ccagcgccgt gccgaggccg tcgccgtgga cgaccacttc accgtggaac tggtcgatcc
    10201 gctgatctcc ttcgtgcgag agggcggcaa acggctccgg ccgctgttcg cctggtgggg
    10261 ctggcgtgcg gcgggcggtg ccgacgcggg cgccgaggcc gatgcggtgc tccgcgcggt
    10321 cagcgccgtg gagctcgtgc acgcctgcgc gctggtgcac gacgacgtga tggacgactc
    10381 cgccatccgg cggggcaagc ccgccgtgca cgtggcgatg gcggcgcgac accgggctgc
    10441 gggcatgcgc ggcgacgacg tgggcttcgg ccggtcgatg gcgatcctgg tgggagacct
    10501 ggcgttgtgc tgggcggacg acatgatgca cacctcgggt gcctcgcagg cgatgctgca
    10561 ccgggcgggc tcggcctggc gggcgatgcg caccgagatg atggcgggtc agttcctcga
    10621 cctgcgggcg caggccaccg gcaccgagtc gatcgagtcg gcgctgcggg tgaacctgct
    10681 caagaccgcc ggatacacgg tcgcccaacc gctgctgctc ggcgcactgc tcggcggggc
    10741 gtcgtcggag ctgtcggcgg cgctgcacgc ctacggtgtc gatctcggga cggccttcca
    10801 actgcgcgac gacttcctcg gcgtgttcgg cgagccggag atcaccggca agcccgcagg
    10861 cgacgacatc cgtgagggca agcacaccgt gctggtcaac gaggccctgc ggctgaccga
    10921 gctgcacggc cgtcccgacg aggcggcgac cttgcgcggc gcgctgggcg acccactgct
    10981 gagcccgcag accctggccg aggtccgtcg agtcctcgtc gactccggcg ccgtcgccgt
    11041 cgtggaacag cggatcgaga ccctggccat ctcggcggtc gaccgactgt ccggggtcga
    11101 tctctcggag tcgacggcgg cccgcctgcg caccctggcg gatgcgatga tccggcgcga
    11161 tgtctgatcc cctggcgcgg cggtggtccg gcgcgctgcg aacgggccgt ggcatgaccg
    11221 gccgtaccga ccacgtcgtg gtggtgggcg ccggattggc gggactgtcg gccaccctgc
    11281 atctactcgg cgccggtaga cgggtcaccg tcgtggaggc cgggccgcgt cccggcgggc
    11341 gggccggtct ggccgagacg gcgggctatc gggtggacac cggccccacc gtgctgacca
    11401 tgccggagat catcgccgac gcgctcgacg cggtggggga gtccctcacc gaccgcctcg
    11461 acctactccc gctgcatccc gcctaccgcg ccgccttcgc cgacggcagc acggtcgcgg
    11521 tgcacaccga cgcggagcgg atggaggcgg agatccgccg cttcgcgggt ccggtcgagg
    11581 cccagggcta ccgcaggctg cgtcgctggc tgaccgagct gtacaccgcg cagtacgacc
    11641 gtttcatcgc cgccaacatc gattcgccca gcgacctggt acacccggcc gccgcccgcc
    11701 tcgtcgcgct cggcgggctg gggcgactcg gcccggccgt cgagcggcgg ataggcgacg
    11761 agcgtctgcg ccgcgtgttc tccttccagg cgctgtacgc cgggctcgcc ccacaccgtg
    11821 ccagggcggc ctacggcgtg atcgcctaca tggacaccgt cggcggggtg tacttccccc
    11881 gaggcggcat gcacgcggta cccagggcgc tggcagccgc cgccaccgcg cacggcgccg
    11941 aattccacta cgacgcaccg gtgcggcgat tggagcgcac cggcgaccgc atccgcgccg
    12001 tgcacaccga tcagggccgc atcgagtgcg acgccgtggt cctcaccccg gacctgcccg
    12061 agacctaccg gttgctcggc cgcaccccgc gtcgcccggt gccgctgcgg tggtcgccct
    12121 ccgccgtcgt gctgcacctc ggggtggcac gcggtgcggc gatgcagacc gatcaccacg
    12181 tcatctcctt cggctcggca tggcgccgca ccttcgccga gatcatcgac gagggtcggc
    12241 tgatgtcgga cccctcccta ctgatcaccc gaccgacccg cagcgatcct gggctggccc
    12301 cgccgggccg cgaactgctc tccgtgctcg ccccggcgcc caacctcgcc gtcggcaggc
    12361 aggactgggc caggatgggc accgcctacc gagacgagct gctcgccgtg ctcaccgacc
    12421 ggggtctgct cgatgccgcg ccggacatcg acctgagcga gctggtcacc cctcgggact
    12481 gggccgcgca ggggctgggg gcgggcaccc cgttctccct ggcgcacacc gtggcccaga
    12541 ccggtccgtt ccggcccgcg aatctcgtgt ccggcatcgc caacgccgct ctcgcgggct
    12601 cgggtaccac ccccggcgtc ggcgtgccca ccgccctgat ctccgggaag ctcgcggccg
    12661 cgcgggtcac cggcgccatg gccggtcggg gatgagtccg ggcgagctgg acgcagcggg
    12721 catcgagggc accgcactgc gtcggtccta tctgcgctgc cgggcgttgc atgccaggtt
    12781 cggccgtacc tacttcctgg cgacgcggct cctgcgcccc gaacagcgac ccgccgtgca
    12841 cgccctctac ggcttcgccc gttgggtcga cgacatcgtc gacgaacccg gcggcgagga
    12901 tcccgcgccg cgcctggacc gggtggccga ccgagtcgcg gccgatctcc acgcgacaca
    12961 cagcacgcac gcggtgttgg cggcgctggt cgataccgtc cggcggtacg ggatcgatca
    13021 ccggctgttc accgacttcc tcacctccat gcggatggac ctcacggtga cggagtaccc
    13081 gagcgaccgg gaactggccg ggtacatccg aggctcggcc gaggtgatcg gcctccaact
    13141 gctgccggtt ctgggcaccg tggtcgccga cgacgtggca gccgagcatg ccgccgcatt
    13201 gggcgccgcc ttccagctga cgaacttcct ccgcgacgtc ggccaggatc tcgatcgcgg
    13261 ccggatctat ctgccgatgg acgaactcgc gaccttcggc gtcgaccggg aactcctacg
    13321 ctggtgccgc cggacgggcc ggaccgagcc gcgcctgcgt cgcgcggtgg cgcacttcat
    13381 cgcgcgaaac cgggcggtct atcgccgggc gctgccggga atcccgatgc tcgccccggt
    13441 cgcgcggccg tgcgtcacca ccgccgcggt gctctaccag gggatcctgt ccgagatcga
    13501 ggccgccgac ttcgacgtgg tgagtcgacg agccgtggtg ccacggcgac gcaggctcgc
    13561 cgtggtggtg cccaccctcg cgcacagcat cgcgctgcgg atgacggccg cccgctgagg
    13621 ccgctcgatg ccctgcggta ccgccgatcc ggcgatggcc agggcggtcc gccgcgtcga
    13681 tcgccgtcac accaacgaga tcggcgcagg tagcgggtcc ggtgatccac caccggtctc
    13741 cttcgcatcg atctcgattg cccgtcaccc ggagtccacc cgcagctcac cgtgattgct
    13801 tacggtgatc cggtcgccac tgtccggaac atcgtggcga gcgtccccct gcgtgcgttc
    13861 gcccagtgaa ggagtctcga tgccgtccac caaagccgtc gctctcggcg ccgcgttctc
    13921 gacgttgatc gcgaccggcc tcgccgtcgc accggtagcc gcccaggcgc agccggatca
    13981 gtccgattca cagggcacca tcgcctggat cagcgacacc cagtactact cgcagcgcta
    14041 cccggacatc ttcaccggca tgaccgagtg ggtggcgtcc gaggccgaca gtcgaggaat
    14101 cgagtacctg gcgcacaccg gggacatcgt cgagtactac cccttcaccc gggaatggga
    14161 caacgcctcg gccagcatgg gagtcctgga ggacgcgggc atcccctacg gcgtcgccgc
    14221 gggcaaccac gatgtggcga ccttctggtc cggctacacc atcaccgact acggcgtgtt
    14281 cagcgagtac ttcggcgagg accgcttcgc cgactcgccg gtctacggtg agtccttcaa
    14341 ggacaaccgc cagcactacg acctcgtcac catcggcggc gtcgaattcg tggtgctgta
    14401 cctggcatgg cggctcgacg cggccgacat cgcctgggcc tccgaggtgc tcaccgagca
    14461 cgccgacaag cccgccatca tcggcgtgca cgagtacatc gacgcgcagg gcgagtacag
    14521 cggtcgtggc gagcagatct tcgacgaact cgtcgagccg cacgacaacg tgtcgctggt
    14581 gatctccgga cacatccacg gtgccgccac caacgtcgtc gaactcgacg gggaccgtcg
    14641 ggtcgtcgag atgctcgccg actaccagga cgccccgcag ggcggatccg gttacctgcg
    14701 tctgctgacc gtcgacaccg ccgcgagcac tctccaggtg cagacctatt ccccgcacct
    14761 ggactcgacc ggttacttcg acgacgccgt cgagaacacc acgctgccgt tggacatcac
    14821 gccctgatcg attcgtcgat cgacggcagc tcgctcgccc gtccgtccga tgtggtctct
    14881 tgggcggcgg gcgagtcctg catcgagccg gcccgatccg acctgtctac caggcggaac
    14941 cccgtcgtgg agcggctgga cccccgcccg ccctacggct gggtctaccc ccgtcgggtg
    15001 gattccaccc ctggagatcc actgtctgac gccatggtga gcggctcgcg acgtacctag
    15061 attttcccta gtcagcaggc gtattcggct gggggagacc atgggattca cgcgggcgtc
    15121 gttaaccgca ctggtggccg cactcgtgct gccctggtgc tcgggctcgg tgaccggacc
    15181 cgagcccgcc gagccgcttc ccggtgccgt cgcctggtcc cgtcaccgag tggacggcga
    15241 agcgctgccc gacgcggagc aggcggagcc gcagacggtc gccgatttcc tcaccgatgc
    15301 gggccgacag aacaccgacg agctcgtcga gcgattcccc ttcgtcatgg gcaatctcga
    15361 cggtgcccca ctccggaccc gcttcgccgc caaccgacgg gccatcgcgt tggaacgcgc
    15421 ccgcctcgcc gccgtcgccg ccgaccagag cctctcggaa cccgcacgct cctcggcccg
    15481 acgcaccgag gcgatgtacc gccgcctggc cgagaaccgt cgaccggtgc tgctcttcga
    15541 tcctcgcggt cggggccgct acgcggaggt acacggcgat ctggcgaacg ccacccacgt
    15601 cgcggtcgtc gtaccgggga cggggatctc gaccagatcc ttcgacccgc gctccggtca
    15661 cgtcggcacc ccgggagcga tggccgccga gctgtaccgc acccaacgcg cactgtcgcc
    15721 tgctgcgtcc accgcagtcg tcgcctgggc gggttatgcc accccgcagg ccctgggcgt
    15781 cggcgcggca accgctcggt acgccgaggc gggggccgag gagttacgcg atctgatcga
    15841 cggactgatc gcggcccgga gcagtcccga cgcgggtcac ccgactcggt cgacgactcg
    15901 ggtgacgctg ctctgccaca gctacggatc ggtggtctgc ggccgggcgg ccgagaagct
    15961 gcccgaagcg gtgcacgaca tcgtcgtctt cgggagcccc ggcatgggcg tggacaccgt
    16021 gacggaactg cacaccgacg cccggctctg ggcggcgttg ggtccctcgg actggattcg
    16081 acatgtgccc aacgtccgat tcctcggctt cggccacggc cgggcaccga cgtcggccgc
    16141 cttcggcgct cggcggatcc cggccaccga cgtccgaggc cacgacggat atctccaccg
    16201 cgacaccgac accgcgcgcc gattcgccca gatctcgctc gacctcgtat ccgagccaca
    16261 ccacaccgga gcggacaccc accgatgacc agtaccgact cgaccgccgt tccccgccgc
    16321 acccgacgag gacgggtacc cgagccacgc cacgcgcggc gcggtctgtc cgcacgactc
    16381 cgggcgatcg acgacgccac ccctgcggag cgcgaccggg tgatcgatgc cctgcgcgcg
    16441 ctggcgatcg tcggtgtcgt cctcggccac tggctggtca gcgtcgtcgt cttcgaccag
    16501 aacgggccgc acatcgccag cccgttgcag catctgcccg agttgacacc gctcacctgg
    16561 gttctgcagt tactcggcct gttcttcttc gcaggcggtt gggccaatgt ccgcagcctc
    16621 gaccgagcct ccggcgggag cgcctcggcg accacccgag gttcgattct cggccgggga
    16681 tacctgccgt ggttgggcgc ccggctggac cggatgctgc gaccggtggt gctgctggcc
    16741 gggttcgtcg cggtgttgct cgccgtgctg ggcctgagcg ggtggacggg ggccgacctg
    16801 tacaccgtcg gactgttcgt cgtcagtcca ctgtggttcc tgccggtcta cctggtcctg
    16861 acggcgggta cgccgatcgt cgacgcggcg gttcggcgct ggggcgcgtg ggcggcagtg
    16921 gggcccgctg cggtcgtcct gctgctcgac ctgctgcggt acggcccgtg gtgggagctg
    16981 cccgcgtccg tgggcacccc gaacctgatc gccgcctggc tggtgcccta cgtgctgggg
    17041 gtggccttcg ccaggggcag gctggtgcag gcggccggac catggctgtt cgtcgcgggg
    17101 ctggcggcct gcgtggcgct gatcgtgttc gccgactatc cggcgagcat gaccggggtg
    17161 accggcgccg accgctccaa tatgggcccg ccctcgctgt tggtccccgc gatggcgctg
    17221 gcccaactcg gggtggcgtt gacgttctac cggcggttgg cccgggcgct gacccggccg
    17281 tggctctggg cgatcgtggt gacgatcaat ctggtggcca tgaccgtcta cctctggcat
    17341 cagacggcgt tgatgtcgac ccagctggcc acccacgcgg tgggactgag ccttctggga
    17401 ttcgacgggg tgcccgccga tctcacctgg ctgttgagtc gcctggcgct gctgccgctc
    17461 tgcggtgtgg tgctgtgcgg cttcatcctg ctcttccgac ggtgggagca gcgcagcgcc
    17521 tccaccgtgt tgcggcccgc cgcaccggca ggagcgactg ccgatgcggc gcggcccacg
    17581 gcggccgatc aggacccgcc gcgccacacc tcgcctgcgg ggtaggcgaa ccgttgtcgg
    17641 gagtcggcga gcatctccgc accggatccg ggatcgatcg gcacctggta ccggccatcg
    17701 cggatccgca ccggggtgct gaaatgctca tgcaggtggt ccacgtactc gatggcccgg
    17761 ccgtcgaggg ctcccgacac ggccacgtag tcgaacatcg ccaggtgttg gaccagttcg
    17821 cagaggccca ctccaccggc atgcgggcac accggaaccc cgaacttggc cgccagcaac
    17881 aggatcgcca cgttctcgtt caccccgccg acccgggtgg cgtcgatctg caggatgtcg
    17941 atcgccccgg cctgcaggag ctgcttgaac atcacccggt tctggacgtg ttcaccggtg
    18001 gcgacccgca tcggcgccac cgcgttgcgg atcgcggcat ggccgaggac gtcgtcgggg
    18061 gaggtcggct cctcgatcca ccacgggttg aactcgcgca gtctgcgcag ccaggggatg
    18121 gccgtatcga cgtcgaagcg ctggttggcg tcgatggcga tccgcacgtc gggacccacc
    18181 gcggccctgg ccaccccgag cctgcggacg tcgtcgtcga gggcggcgcc gaccttcaac
    18241 ttgatcaggt cgaaaccctc ggcgaccgcc tcggtcgcca acctcgccaa cttggcgtcg
    18301 tcgtaaccga gccaccccgg cgaggtggtg tagccgggat agccctcgcg ttcgagtcgc
    18361 tgtagccgct cggatcggcc gggttcggcg gcccgcagga tctccagcgc ctcgtcgggg
    18421 gtgagcgcgt cggtcagata gcgccagtcc accaactcga cgatctgctc cggagtcagg
    18481 ctcgccagca gtcgccacac cggcatcccc gcgcgcttgg cggccaggtc ccacgctgcg
    18541 ttgaccacgg cccccaccgc catatgcatg acgcccttct cgggaccgag ccagcgaagc
    18601 tgcgagtccg agaccagctc ccgggacagc ccgcccaggt cggcgcacaa cttctcgaca
    18661 tcgcggccga cgacgtgcgg ggcgagcagc tcgatcgccg cgcactggac gtcgttgccc
    18721 cgaccgatgg tgaacacgaa accatggccg tcgggaccct cgtcggtccg cagcaccaga
    18781 taggcggcgg agtagtcggg atcgggattc atggcgtccg agccgtcgag ttcccgggag
    18841 gtcgggaatc ggacgtcgga cacctccagg gcgacgatcc ggctcacgcg gcctcgccct
    18901 ccggcccggt catcacctgt cgctgtctgc cgaggccgtc gatctccaac tccacgacat
    18961 cgcccgcacc gagatagggg aaacgaccgg agagcgccac accctccggg gtgccggtgt
    19021 tgatcacgtc gccgggttcc aacgtgagga atcggctcag gtgccacacc aggaacgcga
    19081 cgtcgaacac catgtccgag gtggcggaat cctgccgggg cgcaccgttg acccaggaac
    19141 gcagccgcag cgactgcgga tcgccgatgt cctcggcggg taccaaccag gggcccaggg
    19201 gattgaagcc gggaccgcac ttgcccagcg accactgccc gccggagcgc tccagctgcc
    19261 actcgcgctc ggagatgtcg ttggagaccg tgtaaccggc gatgtgcgcc gccgcatcct
    19321 cggggcctgc gagtcggctg gcgcgcttgc cgatcaccac ggccaactcc acctcccagt
    19381 cggtgcgcga actgcccggc ggaatccgca ccgcgtcgtc cgggccgacg atggtgttgg
    19441 ggtgcttgaa gaacaggatg ggctgggcgg gtggttccgc cccggactcc cgggcgtgcg
    19501 cggcatagtt ctggccgatg cacagcacgg ccatcggccg ggcgatcggg gcgccgatgc
    19561 gtaacccggt cggatccagc gcgggcagcg tgcctgcggc caacgccgtt cgggcccggt
    19621 cgatgccctc ggcggcgagg aacgcgccgt cgatgtcgtc ggtgatcggg ctcagatcga
    19681 agaacgcgcc gtcgtccgtt cgcagggcgg gacgttcggc cccgggtgca ccgagtcgca
    19741 gcagccgcac gggtactcct ctcctaccgc cgtcacaggc ggtgtctcgg atggttcgga
    19801 attctgtgtc gcccatcggc ggcatccgcg ccccgacctc acggcgggtt cccggtgtcg
    19861 aacagcgggc gtagccgctc gtagtaggag gcctccagat gcgcacgcat cgccaatttc
    19921 gccgccacgg gatcgcccgc gacgacggcc tcggtgaccc gccgatgctc ggccagcgcc
    19981 atcgtcgcga tccgctggtc gtagtagagc cggaagatat gcagatgaca gtgggtctgc
    20041 tcgaaggcgc gacggatctg cgcgctcccg gagagctccg cgatgaggag atggaagcgg
    20101 gtgtcgtgca gggccagggc ctggtagcgc tgcgaatccg gcggcgcgca ggaatccagc
    20161 tccgcccgca atcggtcctt cgcgggctcg gtggcgcctc gggcggcctc ggcggcggcc
    20221 cagggttcca gcagcagacg gaagcgatag agatcgtcca gctgctccag cgtgagcaac
    20281 gcggtggtgc gatacccccg cagcggctcc ttgaccacca gctcggtcga ctccaaccgg
    20341 gccagggcct cccggaccgg ggtgggggag acctcgagtc tgcgggccag accgtcgatg
    20401 gacagccgct cgcccggggc gatggcgtgg tccatgatca gattcttgat cgtctcgtag
    20461 acctcgtcga ccaacacgct ccggcggggc gcactcgggg cgcgggccgt cgtcgacccg
    20521 gaacccctcg gtgcagcgtt catcccgtgc tccccggtgc ctgcgcccga tccgttcgcg
    20581 gccgctggtt cgcaccctag gggtcggcgg cgccggatcc tataggattc gccggccgtc
    20641 ttcggccgaa ccggtcaccg aggccgctcg ccgaagccgt ttcggggcac gcggcgagca
    20701 ggccggcagg gttcccaccg gcctgcaccg ctgcccgtgg cggcggtgcg acgagcctcc
    20761 agcacctagc gcaggcggcg gaacctcagc ccgaggctgt gagcggtcgt cggcggccgt
    20821 ccggcgaacg gttgatcgag gcggcggagt cacgacgtcg accaccggcc gattcggcgt
    20881 gcgtgtcacc atcggatcgt cgatcgagcc tgtcatccgg ggcgtggcgt tcggcctgtt
    20941 ctgcgacgtc cctggccagc gccgcccgca gccccggcct gcgatcggcg tagacggggc
    21001 gcggcggtgt gaaggcaggt gtgttcctcg ccagcgcgcg gaccagattc ctcaggaagc
    21061 cgtcattcat cggcacctcc actgtgcggt gaaacggcgg gtgcggggcg gggtgcctgc
    21121 tccacggaac ggatccgctc cgcatcggtg tcgcgccagg cgatgtcccg gcgctgcggg
    21181 ccctccgggg cctgcggtgg acgggatgcg tcggcggcgg gcagcgctct ggtgagctgt
    21241 tccaccagca gcggggccgc cacgccgatc gcgagcgcgc cgaagggccc actgacctga
    21301 cccgcgatac cggcagctgc ggccaacccc gaaccgacac ccagtcggat cagaaccgag
    21361 accaacaggg gaagcggccc cggctcgtcg ggaacccgcc acggccaggt gcccgtccgt
    21421 cggatcgcgc cggagaactc gagaccctcc acggcgaagc caccgaagag tccccagagc
    21481 gcgtactccc atcccaccac cgccctaatg taacgctcgg tgtatcggag gtgactcggt
    21541 catggtcgat tctaggccgt gcgaccacgg tcgtccgcga tccgtactcc atcggccggc
    21601 gtcccctccg gccgcgatca ccaccgcccc cagcgatcct cggagcgctc ccgaggatgg
    21661 cgccgtgcgc ggaggatcga gcgctcacct gggcggaggc actggtcggc gcggtaggtg
    21721 gagccgaatg gtgcggtcgc ggagaagcgg cggaaaaatc ttctcggaaa gttctgtcga
    21781 cgtgtcgatc cggccgtcga ccgttcgacg cactagtagg gcccgggaac ccatcccgtc
    21841 accgacgggt gtccgggccg ccaaccgagt gacaggggag cccccatgcg attcatggtc
    21901 ttggtcaagt ccgatgccga caccgaggcg ggcgtgcttc cgagcgagga actgctcacc
    21961 gcgatgggcc gctacaacga ggagctggtc gcggcgggcg tcctgctcgc aggcgagggt
    22021 ctccaggcca gccagaacgg cgccagggtc cagtggaacg acggcgccgc cccgacggtg
    22081 gtcgacggcc cattcgcgga ggccaaggag ctcgtcgccg gattctggat cctgcaggtg
    22141 aagtcgaagg cggaggccat cgagtgggcc aagcgctgcc cggccccgga acagggcgag
    22201 caggtactgg aggtccgaca gatcttcgag atggacgact tcggcgacgc cgcgaccccg
    22261 gaggtgcgcg agtcggccga ggcgctgcgg tcgaagaccg agaagaagtg agcggccgcc
    22321 ccctgattca cggcctcgga ctcggcctcg ccgtcgaacc gggggcgccg gagggggcga
    22381 aaccctcccg atagccgacg ccgtgtgctt gggtcggagg tcatgacggc ttccgaccct
    22441 cgccctgcga tcgacgcggt gtggcgaacc gagtcggcgc ggctcatcgc aggcctcgcc
    22501 cgattcctcc acgatgtcgg ccttgccgag gagttcgcgc aggacgccct ggtggcggcc
    22561 ttggaacagt ggccggagac cgggattccc cggaatccgg gagcgtggtt gacgaccatc
    22621 gcgaaacgtc gggccatcga ccatctccgc cgtagggaac gcttcgcggc caacctcgtg
    22681 gagttgggcc gcaatcaggg cgtggacggg gtcgggaccg cgccggatgc ggcgagcgag
    22741 cagctcgact ccgacgacat ccaggacgac ctgcttcgcc tggtgttcgt ctcctgccat
    22801 ccggtgctgt ccaccgatgc cagggtcgcc ctcaccctgc ggctactcgg cggtctgacc
    22861 accgaggaga tcgccagagg tttcctggtc ccggagtcga cggtggccca gcggatcgtc
    22921 cgggccaaac gcacgcttac caaggccggg gtgcccttcg aggtacccgc ccctgcggac
    22981 cgaccagccc ggatcgcctc cgtgctcagc gtgatctacc tgatcttcaa cgagggttac
    23041 gcggcgacct cgggcgagga ctggatgcgg cccgccctat gcgaggaggc gttgcggctc
    23101 ggcagggtgc tcgccggact gctgcccgag gacgccgagg tccatggtct ggtcgccctg
    23161 atggagatcc aggcgtcgag gatgcgggcg cgcacctcgc ccaccggtga tcccgtgttg
    23221 ctgctcgacc agaaccgagc ccggtgggat cgactgctca tcaatcgggg actcgcggcc
    23281 ttggaacggt cggaggccct cgcacacccg cgcggaccgt atgcgatgca ggctgcgatc
    23341 gcagcgtgtc atgcgcgggc ccgcaccgcc gaggagaccg actggatccg catcgccgcg
    23401 ctgtatcaag cgctcgccct gcagacgccg tccccggtgg tggaactcaa ccgggcggtc
    23461 gcgctgtcga tggccttcgg accggcggtg ggactggaac tggtcgacac gctgaccggg
    23521 gaaccgagcc tggcggccca tcacctgctg ccgagcctgc gtggcgatct gcttcggcga
    23581 ctcggccgcg attccgaggc ggccaccgag ttcgccag
//
