LOCUS       NZ_CP017157            22238 bp    DNA     linear   CON 31-MAY-2024
DEFINITION  Streptomyces lydicus strain 103 chromosome, complete genome.
ACCESSION   NZ_CP017157
VERSION     NZ_CP017157.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces lydicus
  ORGANISM  Streptomyces lydicus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8201357)
  AUTHORS   Jia,N., Ding,M.-Z., Gao,F. and Yuan,Y.-J.
  TITLE     Complete genome sequencing of Streptomyces lydicus 103 and metabolic
            pathways analysis of antibiotic biosynthesis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8201357)
  AUTHORS   Jia,N., Ding,M.-Z., Gao,F. and Yuan,Y.-J.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2016) Key Laboratory of Systems Bioengineering
            (Ministry of Education), Tianjin University, Tianjin 300072, PR
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 100x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001729485.1-RS_2024_05_31
            Annotation Date                   :: 05/31/2024 02:23:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,288
            CDSs (total)                      :: 7,195
            Genes (coding)                    :: 7,061
            CDSs (with protein)               :: 7,061
            Genes (RNA)                       :: 93
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 47 of 134
            Pseudo Genes (incomplete)         :: 104 of 134
            Pseudo Genes (internal stop)      :: 11 of 134
            Pseudo Genes (multiple problems)  :: 26 of 134
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:52:31
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7923763
            Orig. end                         :: 7946001
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017157.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Source DNA is available from Prof. Ying-Jin Yuan.
            Annotation modified by submitter.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22238
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="31"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22238
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22238
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12238](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12238)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    703..717
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.1"
                     /tool="antismash"
     misc_feature    1464..1479
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.33"
                     /tool="antismash"
     misc_feature    2030..2041
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     misc_feature    complement(2409..2424)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.13"
                     /tool="antismash"
     gene            complement(2865..3410)
                     /locus_tag="SL103_RS38460"
                     /old_locus_tag="SL103_34330"
     CDS             complement(2865..3410)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539347.1"
                     /locus_tag="SL103_RS38460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_34330"
                     /product="hypothetical protein"
                     /protein_id="WP_069572876.1"
                     /transl_table=11
                     /translation="MDALAKPADGQPEPGTAVAVRDVVRSVVAELAPDELVLVEGLWRY
                     DDDSVVARLAGRRRAREPLGFGLQEVTALITPVAWLVLDEAARKVVGAAVTGATDRTKG
                     WLRRVTRRPAAARTLPPLSEEQLAAVRARVLELGTESGLAPETATALAERVVARLVLRP
                     QGRLANDAGGDGPAEPEA"
     gene            complement(3504..5447)
                     /locus_tag="SL103_RS34335"
                     /old_locus_tag="SL103_34335"
     CDS             complement(3504..5447)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089916.1"
                     /locus_tag="SL103_RS34335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_34335"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_079146338.1"
                     /transl_table=11
                     /translation="MHLRTSRGQPAPTEEPPPPPQPGTESPPVDTRLWSRQTDPTIRTR
                     RVGLKESLRRFWPLTHGDRRWILLVCLAAVAAALAETAAILLFAQLTDKALQKGSVSAF
                     WQPASLWLGVAVVGAVVGYLGNSLAAWTAERFVMRLRARVFAHLQTLPPHFFQRSRRGD
                     LVERMTGDVDAIEQMLITGLVQAAAALFGIIFYAGAALWLRWDLALATFVLAPLFWAAT
                     HRFTGRVKEVSRRERAADGAITSVVEEGLVNVVLTQAYNRQRDEEERLDHQARRWFRAS
                     VTSARLQGLYDQVVELLETVCVLTIIGLGAWEISAGRMTLGQLLAFAAFVGYLYPPIRS
                     LGQLGLTATEATAGAERLLEILDARPAVTDPAPSLVAPPRHGRALGEVEARHVHFRYPG
                     GSEDALHDFSFTAVPGELLVITGPSGAGKSTLAALLLRFYDPDAGTVRLDDVPVHRMPL
                     AQLRHNITLLPQDTLVLHDTVEENIAAGRPHGRATHHDVERAARAADAHDFITALPDGY
                     DTVIAPGTARLSGGQLQRIAIARAMLRDAPVLVLDEPTTGLDVLATQRILGPLRRLAEG
                     RTTLVITHDLDLAADADRVLVLDHGLLVESGTHPQLLAQRGLYATLFHAHPPPHPHNGT
                     ANPAAERRGMVG"
     gene            complement(5558..5695)
                     /locus_tag="SL103_RS38185"
     CDS             complement(5558..5695)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SL103_RS38185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_164492939.1"
                     /transl_table=11
                     /translation="MSFRKVFPRRRRDGWDHDHDRRRRRRRYGRRYGRRRRFFGYDNFY
                     "
     misc_feature    complement(5789..5803)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.75"
                     /tool="antismash"
     misc_feature    5798..5812
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.5"
                     /tool="antismash"
     misc_feature    5930..5944
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.04"
                     /tool="antismash"
     gene            complement(6070..6846)
                     /locus_tag="SL103_RS34340"
                     /old_locus_tag="SL103_34340"
     CDS             complement(6070..6846)
                     /GO_function="GO:0003906 - DNA-(apurinic or apyrimidinic
                     site) endonuclease activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014673912.1"
                     /locus_tag="SL103_RS34340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_34340"
                     /product="DNA-formamidopyrimidine glycosylase family
                     protein"
                     /protein_id="WP_069574384.1"
                     /transl_table=11
                     /translation="MPELPDVEAFRATFACCARRRVVRHIEVRDAGVLHGLSARQLRHA
                     LEGRRFAAPERHGKWLIARTGGPTLLLHFGMTGRLVCTAPEEADHPHDRVVFTMSRHHL
                     LRYRDQRKLQGLWLVDAAGLDRVLGGLGPDAATVPRGALRAALAGRRGRLKAVLLDQTV
                     LAGLGNLLVDEILWRTRLPPSRPARDLTDEEGDRLHTELRRTLRAAVRAGCVPPRDSWL
                     TGRRDDPDPRCPRCGGPLRRGRVAGRGTVWCARCQP"
     gene            complement(6888..7469)
                     /locus_tag="SL103_RS34345"
                     /old_locus_tag="SL103_34345"
     CDS             complement(6888..7469)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089901.1"
                     /locus_tag="SL103_RS34345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_34345"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_069572878.1"
                     /transl_table=11
                     /translation="MAERKARADALRNRETVLAAADELFARSASPRTVSMDEIAAAAGV
                     GKGTLFRRFGDRTGLIRAVFEARIEPLRTAVTDGPAPLGPATPPRERVPALLDALLRFK
                     LENRHLSLALEEAGSGSPYQAAHYAWWHGTLRDTLRRLPGHEDADFTAHALLAATRADL
                     VEHLAGEEGTAPARMRAQLAAFVGRVLGQG"
     gene            7576..7992
                     /locus_tag="SL103_RS34350"
                     /old_locus_tag="SL103_34350"
     CDS             7576..7992
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004945142.1"
                     /locus_tag="SL103_RS34350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_34350"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_069572880.1"
                     /sec_met_domain="PF07366 (E-value: 1.4e-05, bitscore: 23.6,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRETDPAALYRHGLRLLLEKDMEGWVALCADDAVLEFPFAPEGYP
                     RRLAGRAEIAAYLRDYPDHIDLRAVPHLKIHRTDAPDTVVVEMRATGRIVATGAPYEMT
                     YVVVVTVADGRITHYRDYWNPLAVPASMSEAKAG"
     gene            7989..8849
                     /locus_tag="SL103_RS34355"
                     /old_locus_tag="SL103_34355"
     CDS             7989..8849
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047606.1"
                     /locus_tag="SL103_RS34355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_34355"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_069572881.1"
                     /transl_table=11
                     /translation="MNDRDTVLVTGATGTTGSRVVARLAALGHPVRAAARRPDGARAVP
                     FDWYDPATHPGALHGADRLYLVPPPGDPDPAAVMLPFLERARAAGARRAVLLSSSALPA
                     GGPGVGRVHAALPGLFDAWTVLRPSWFMQNFTGGHPHAQDLRERGVLTTATGGGRVGFV
                     DADDIAAVAVRALTAEPALPAGDLVLTGPQALSYDEVAAVVSEVTGRPVRHRAIGHEAL
                     RDRLAAGMPAEFAALLAGLDRAIAGGAEDRVTDTVQRLTGRPPRAFRTHAQAHWSGGAA
                     RIPTP"
     gene            complement(8937..9809)
                     /locus_tag="SL103_RS39360"
                     /old_locus_tag="SL103_34360"
     CDS             complement(8937..9809)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SL103_RS39360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SL103_34360"
                     /product="hypothetical protein"
                     /protein_id="WP_069572883.1"
                     /transl_table=11
                     /translation="MRHKTAFLGAVAATGAFALLGPIAAQATTGTITFHMRSRNKDYQI
                     VDPGDDHCYGLGDGGGLVDNDTPLDLVLWSSRDCTGRSMATVRAGSSARFARYGSLRLD
                     PASAPAPSYPDESRDREDARDPGDSRDPGDYRDPSDSRDPGDSRDPGDYRDPSDRRDSG
                     DSRDPGDYNDPSDSRDPGRDRDPGDSRDPRDSDDHLDPGDARDTGDSPDRRDPQDPARS
                     SDPGDPSTLPAPAGASDPVNSEGAAAPRRVARPSSVAPKSSARPRRVARPSSSSPTKSS
                     ARPKVSKRS"
     misc_feature    complement(9849..9863)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.65"
                     /tool="antismash"
     misc_feature    complement(9849..9863)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.01"
                     /tool="antismash"
     gene            complement(10001..12238)
                     /gene="cyc2"
                     /locus_tag="SL103_RS34365"
                     /old_locus_tag="SL103_34365"
     CDS             complement(10001..12238)
                     /EC_number="4.1.99.16"
                     /EC_number="4.2.3.22"
                     /EC_number="4.2.3.75"
                     /codon_start=1
                     /gene="cyc2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432595.1"
                     /locus_tag="SL103_RS34365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_34365"
                     /product="germacradienol/geosmin synthase Cyc2"
                     /protein_id="WP_069572885.1"
                     /sec_met_domain="T1TS (E-value: 1.5e-84, bitscore: 283.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKPFELPDFYTPHPARLNPHLEAARTHSRKWARAMGMLEGSGIW
                     DERDLDAHDYALLCAYTHPDCDAEALSLVTDWYVWVFFFDDHFLEKFKRTLDRAGGKEY
                     LDRLPAFMPTDPGAPVPEPANPVEAGLADLWARTVPHMSADWRRRFAESTEHLLNESLW
                     ELSNININRVPNPVEYIEMRRKVGGAPWSAGLVEYATGAEVPARVAGSRPLRVLRDTFS
                     DGVHLRNDLFSYQRETEEEGELSNGVLVLETFLDCTTQEAADAVNDLITSRLQQFENTV
                     VTELPALFLEKGLDPKSCADVLAYAKGLQDWQSGGHEWHLRSSRYMNDGGAAAGSARPW
                     SPFSAGGLGTSATDLRKALATAGAHRLRSHTHVPHQQVGPSRIPDIRMPFPLTLSPHLD
                     GARRRVVAWAGRMGMLQPQPGVPLSDVWDEAAMVRHDLALCAAGLHPDATPDQLDLGAA
                     WLAWGTYADDYYPQVFGRTRDAAAAHACTERLKLFMPLDPATTPPEPVNAMERGLADLW
                     PRTTRAMAPEARRGFRAAVDTMTAAWLWEIDNQIQHRVPDPVDYIEMRRATFGSDLTMA
                     LSRIGHGRQVPPEVYRTGTLRALENSAADFACLLNDVFSYQKEIEYEGEVHNGILVVQT
                     FFDCDYPTALAIVHDLMTSRMREFQHLVAKELPVVCDDFQLSAEARAALDGHVRELENW
                     MAGILNWHRGCRRYIEPELRHPVGSPGRLGAPSGLGTSAARFFQRPVARVG"
     gene            complement(12392..13219)
                     /locus_tag="SL103_RS34370"
                     /old_locus_tag="SL103_34370"
     CDS             complement(12392..13219)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057092.1"
                     /locus_tag="SL103_RS34370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_34370"
                     /product="alpha-L-glutamate ligase"
                     /protein_id="WP_069572887.1"
                     /sec_met_domain="RimK (E-value: 6.7e-09, bitscore: 34.3,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIGLITADAAHPVLAATGALLLQGGHRVEVVDPGGGHEDPGPLA
                     DVYLLKARTPRALVLAARLEERGAAVVNSAAATARCQDRVAMAELARGAGLPFARTRFV
                     GTPAELAAAGEPAGPLVVKSRHSRRGDLVARADSAVRLRELAAEWPGEPVVVQDFLAGS
                     GWDHKVWVVDGQLFAGLRRSELAPEGRGGTLPLPPGELPADWRALALRAGEVFGLEVYG
                     VDFLDAGGAAPLLVDVNAFPGIRGQAGAPEALAELALRTGARAGRRASESGPE"
     gene            complement(13216..14115)
                     /locus_tag="SL103_RS34375"
                     /old_locus_tag="SL103_34375"
     CDS             complement(13216..14115)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089893.1"
                     /locus_tag="SL103_RS34375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_34375"
                     /product="hypothetical protein"
                     /protein_id="WP_069572889.1"
                     /sec_met_domain="RimK (E-value: 4.2e-08, bitscore: 31.7,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLCFLVEEQYRYDGMPLDVIRQLTAWGHQVDVMWPGRSLLPLSE
                     AVRAGSHDAWVLKTVSGGPGLSLLEAAAAVGLTTVNDVRAIRGVRDKALAAVIARGSGL
                     PVPVTYAAARAEEFAQIPEAEFPLVVKPADGSSGRAVRLVESPDRLPAAGAAEPAEPGG
                     AAGGLLIAQPYVPNSGTDLKVYCVAGELYATERRSPLHPGHAVRERQVPLTAEVARITA
                     EIGTVFGLDLYGVDVLLGPDGPVVVDINDFPSFRQVPDAVARVSSAVLRLARKGAEPAV
                     PGPAAPAVPPLAAIGGDR"
     misc_feature    14249..14266
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.84"
                     /tool="antismash"
     misc_feature    complement(14366..14380)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.09"
                     /tool="antismash"
     misc_feature    complement(14367..14380)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.12"
                     /tool="antismash"
     gene            14628..15914
                     /locus_tag="SL103_RS34380"
                     /old_locus_tag="SL103_34380"
     CDS             14628..15914
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016467918.1"
                     /locus_tag="SL103_RS34380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_34380"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_069574386.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 4.4e-41, bitscore:
                     139.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVPELLLLPEGPARGRAVLVDGGKFRAVGPAEQLLAAHRDLRPV
                     RLDGHLLMPGFVDAHHHLTQSFGKAQSFGQPSEIFKTVWEPLEHALDEESAYVSAKLAA
                     LEALRGGFTTVADAGTRAPVDVRAVAKGTEEAGIRCVLGKIVSSGTGGPEHLGRWEGHP
                     LVHPSLAIAVPEDAPADVLRKTADLCAEAGAVLQVHVNEHLASVERSLKSTGRRPLEYL
                     HHIGALGPHTLGAHATLLTPSETRLLADSGAAVSYNPVASAWKGNGVAHATLLATLGVR
                     FGMGTDGTRGDGFRLIDAGETAQRLAYGMAAGDSVCGAGRTWLEHATSGSADALGLGGV
                     TGEIAAGKAADFLVVNLDVPELTPSYDLRWELVRLANRDQIAAVVVGGKLRLWHGWPTD
                     WDGPALVARAAELGPEVVRRAGIQRVEPV"
     gene            complement(15949..17514)
                     /locus_tag="SL103_RS34385"
                     /old_locus_tag="SL103_34385"
     CDS             complement(15949..17514)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471097.1"
                     /locus_tag="SL103_RS34385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_34385"
                     /product="MFS transporter"
                     /protein_id="WP_069572891.1"
                     /transl_table=11
                     /translation="MSPTSLSREGVGAAAAVPGAPRGALTLAMCLCVTLVVGMVSAVNL
                     ALPTLAASALHPSAQALVWVVDGYVVVFACLLVPAGALADRRGRKGVLLCGTGVFTAGC
                     AVCALAPGAGVLIAGRMISGAGAAAVLPTTLALLVEGRDERSRRRAVAGWASMTGLAAV
                     LGNVGGGAAVEYGGWRTLFGCAVPPALAALVLAGVVAPVGARHPRPVAPLGSALLTGGF
                     LALLYGLVSGPEEGWRSPAALGSLGAAALLLTGWVRCELRAERPLLDPRLFARPAVRAG
                     ALGMAALFTGMFGLFYLNGQYLQYAKGHGPFGAGLRLLPMAAALLAGPRCGLLMERRCG
                     RRGTVVTGMLVLAAGLGTVSTADAHTPYARYALGAGLTALGCGLATPLLSHAMMAALPP
                     ERAGAGSGLQSLAREVGSALGIAVTGTLTTAVFTARLPAALSGPGGPTTVAAAEAGSSG
                     PRMRAAVVDAFTAGLHTATLTLAAVVTVVALLVARWIPPDRSRTRGAGRRRPAPDTAPG
                     RPRR"
     gene            complement(17489..18280)
                     /locus_tag="SL103_RS34390"
                     /old_locus_tag="SL103_34390"
     CDS             complement(17489..18280)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020120575.1"
                     /locus_tag="SL103_RS34390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_34390"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_244304111.1"
                     /transl_table=11
                     /translation="MQRATVRDDGAGDGLTRADRARRVANVLRGQVLRGAFADGVLPDE
                     RALVAEFGTSRNTVREALGLLRDEGLVARRRGVGTVVVGRAYQHPLGELSGLAEVLQRH
                     GTVVNEVREARTVRPPLTVARRLGLADGTPAVYLERLRRVDGRPLSLDCTYLIPEVGEP
                     LLARGRETLERHDVFGLIERVAGAPLGRAEVSVQAVVADPATCAVLAMPEGGAVLAVER
                     LTRLADGRPADLEFIHLRGDRLTLHATLDRAARHVADLPVT"
     misc_feature    18330..18347
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.25"
                     /tool="antismash"
     gene            18487..18993
                     /locus_tag="SL103_RS34395"
                     /old_locus_tag="SL103_34395"
     CDS             18487..18993
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604224.1"
                     /locus_tag="SL103_RS34395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_34395"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_069572893.1"
                     /transl_table=11
                     /translation="MTHKAVPFDELDRKIVAALIDNGRASFAEIGTAVGLSSTAVKRRV
                     DRLRETNVITGFTATVRPAALGWLTEAYVEVYCDSAAPPRRLAEVVRNHPEIAAAMTVT
                     GGADALLHVRATDVEHFEEVLERIRTEPFIRKTISYMVLSHLLPDSPEAGGRGHATGSD
                     AGKQR"
     gene            19163..19975
                     /gene="ddaH"
                     /locus_tag="SL103_RS34400"
                     /old_locus_tag="SL103_34400"
     CDS             19163..19975
                     /EC_number="3.5.3.18"
                     /GO_function="GO:0016403 - dimethylargininase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ddaH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662066.1"
                     /locus_tag="SL103_RS34400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_34400"
                     /product="dimethylargininase"
                     /protein_id="WP_069572895.1"
                     /transl_table=11
                     /translation="MPTSRVASPRRFLVCEPEHFEVRYAINPWMRAEVPVDTARAARQW
                     STLIETYRAHGHAVESVPPVPGLPDMVFAANCAVVMRGRVFGSLFHAPERRPESTAYET
                     WFKAAGFDVYRPESVCEGEGDLVPAGRFLLAGTGFRTARAAHHEAQEFFGVPTIGLQLV
                     DPHFYHLDTALFALDEENVAYYPDAFSPGCREVLARLFPDAVLATREDAMAFGLNSVSD
                     GRHVFIAPQATGLIDQLTDRGYVPVPVDLSEFHKAGGGIKCCTQEIRS"
     gene            19972..21207
                     /gene="rocD"
                     /locus_tag="SL103_RS34405"
                     /old_locus_tag="SL103_34405"
     CDS             19972..21207
                     /EC_number="2.6.1.13"
                     /GO_function="GO:0004587 - ornithine aminotransferase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (37-357). E-value: 1.8e-99.
                     Score: 324.9. Matches aSDomain:
                     nrpspksdomains_SL103_RS34405_Aminotran_3.1"
                     /codon_start=1
                     /gene="rocD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089890.1"
                     /locus_tag="SL103_RS34405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_34405"
                     /product="ornithine--oxo-acid transaminase"
                     /protein_id="WP_069572897.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.5e-112, bitscore:
                     375.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPTRTAVVGAPRSSAELIQAEAPVLAHNYHPLPVVVARAEGVW
                     VEDVEGRRYLDMLAGYSALNFGHRHPDLIEAAHRQLDQLTLTSRAFHNDRLAGFAEGLA
                     ALTGLDMVLPMNTGAEAVESGIKVARKWAYDVKGVPTDRATIVVAGGNFHGRTTTIVGF
                     SDDDTARVGFGPFAPGFRTVPYNDLAALEAAVDETTAAVLIEPIQGEAGVLIPDDGYLT
                     GVRELTRRAGCLFIADEIQSGLGRTGTTLAVEYESVVPDVLLLGKALGGGIVPVSAVVA
                     RRDVLGVLGPGQHGSTFGGNPLAAAVGSAVIGLLATGEFQRRAAERGEQLRAGLAALTG
                     KGVTGFRARGLWAGVDVDPALGTGREISERLLKEGVLVKDTHGSTIRLAPPLTITEEEL
                     ASALASLERVLG"
     aSDomain        20083..21042
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SL103_RS34405_Aminotran_3.1"
                     /evalue="1.80E-99"
                     /label="SL103_RS34405_Aminotran_3.1"
                     /locus_tag="SL103_RS34405"
                     /protein_end="357"
                     /protein_start="37"
                     /score="324.9"
                     /tool="antismash"
                     /translation="VARAEGVWVEDVEGRRYLDMLAGYSALNFGHRHPDLIEAAHRQLD
                     QLTLTSRAFHNDRLAGFAEGLAALTGLDMVLPMNTGAEAVESGIKVARKWAYDVKGVPT
                     DRATIVVAGGNFHGRTTTIVGFSDDDTARVGFGPFAPGFRTVPYNDLAALEAAVDETTA
                     AVLIEPIQGEAGVLIPDDGYLTGVRELTRRAGCLFIADEIQSGLGRTGTTLAVEYESVV
                     PDVLLLGKALGGGIVPVSAVVARRDVLGVLGPGQHGSTFGGNPLAAAVGSAVIGLLATG
                     EFQRRAAERGEQLRAGLAALTGKGVTGFRARGLWAGVDV"
     misc_feature    complement(21385..21398)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.21"
                     /tool="antismash"
     misc_feature    21503..21518
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.15"
                     /tool="antismash"
     gene            21526..22053
                     /locus_tag="SL103_RS39470"
                     /old_locus_tag="SL103_34410"
     CDS             21526..22053
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020622.4"
                     /locus_tag="SL103_RS39470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_34410"
                     /product="phospholipase"
                     /protein_id="WP_069572898.1"
                     /transl_table=11
                     /translation="MSLAGAALSGVLALSAATPALAGPAHPDGSTVRTSAATADHQAAA
                     ISKAQKLKRLNQLTEKYGMPLWENTRVKWQDGHDAYHFDWSTDGCSHVSDNPGGFHFWE
                     SCARHDFGYRNYKKMHEFTRAHKKRVDDSFLQDMQNQCRRQWGPYTELQRKGCLKVAKK
                     YYDAVRTLGHLQ"
     misc_feature    complement(22209..22229)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.33"
                     /tool="antismash"
ORIGIN
        1 gggtgttcgc gccgatgtcg atgaagctgc gcatggctgc cgcgaagacg gtgagctttc
       61 cctgctcgat gccgcggcgg cagtcggcac cggcctgctt gctgcgctcg tgcagcttcg
      121 cccaccgcgc ctgggtcgcc gagcgcggga ccgggaagta cgcggcggtc tccgtggcga
      181 ggtgttcgag ggcgacgcag tgcggacgga tgcgggtggc cgcgaatccc cggtcggtga
      241 gggccgcctt gtcctgcagg gccgagagga cggccagcac ctcggtcgtg aagcgcgcca
      301 tcagcccggt accgccgagc cggagccagg cgtcggtctg tgcggcgagg acctggggtg
      361 agggggtggg aagcgcggcg gtggggatca gttgctgctt ggtgagtgag gtgcggccgg
      421 tgcccgcgtc cctcgggagg ctcgtcgcgg tggtgagcgc gagcaccgcg aggcagaccg
      481 tgccggccac cgcgcgccgc agcaccagcc gttcccgccg gggcgcgggc ccgccggccg
      541 gtggggaggc cgcggcggtc cggcggcgcg ggcgcagggc cccgcgcgcc gccgtgcaca
      601 ggagggcgac gacggcggag acgaagatgc ccaggccgag gaccagcggg aacagcagct
      661 gggtggtcgg ccagaccttg gcgggcgacc agtggcagct ggtggcgagc gtgttcagcg
      721 ggcccagaca gccgtcggcg gtgccgagga cggccgcacc ggccaggccc agcaacgccg
      781 ttgtgcccgc cgcgaccagc gcgacgagca gcgcgaagcg ccgggtcgtc aggctggtca
      841 ggacggccgc ggcgagcgtg ccgcagacca ggacgagcag cacgcacgcc aggtggacca
      901 gcatgtacgt gccgtagcgc cgctccgggg gcggctgcca ggtgtgcatg acggccatca
      961 gggcgaccgt gcccgcccag cacagcgcgg tgcccgcggc ggtggcgagc aacacccggc
     1021 gcagcggcgg cagcagcggc ccggagagct ccggggcggg ggcgccgcgc agcgcccggc
     1081 gggcccactc cggtgcgccg gtcgccggcc gccgcgtcca ggcgagcagc ggcagcagcc
     1141 acagcaccgc cgcggcccag ccgatgaagg ggtccgtgcc gatcggcagg agcagcggca
     1201 gcaccgcggc gaatccggcg agcacgtcgc ggtccccggg gacggcgccc ggcagatcgt
     1261 gcagcagcgc gtcccggata ccggtcccgg agtacgccca gcccgtcgtg aaggtgtgcc
     1321 cgtcggcctg ccaccaggcg taccacaggg cgaagaccac ccagatcgcg gccagcccca
     1381 ggagcatggc gggccggagc gtgcggccgc gccaggagcg caccgacagc tcggcgaact
     1441 gcgccgtcca gcacatgatt ccgacgctga tgacgatcag caccgcgagc gcctcggggt
     1501 ggttgggcag ccaccgcgtg ctgccggagg tgctgctcgt cagcagctcg ccgaccgcga
     1561 ggccgagccc ggtccaccag cccgcgcgca gccccgtggg gatccggccg ccggtgagca
     1621 ccgcccgcgc cacgccccgc cacacggaga cgccggggat cgccgcgatc agtcccgcga
     1681 gcagtgccgt cagcacccgg agcgccccgc cggaccgggg gccgtccagc agatcggtca
     1741 gctggtcgcc ggcgatcgtc gcggtggcgc cggccacgaa cagggtcagg gcgtgcggtg
     1801 cgaagagttc ccgggggtcg gtgagcgcgg ccacccgccg gtcccatgcc gggtgggtgc
     1861 gccacagcgc ggtgaacgag gccagcgccc tccgggtccg gccgggtgcg gcggccttgc
     1921 cggggccgtg cgcggcggcg tggtgccagc cccgggcgtc cgctccccag gcgagggcgt
     1981 cgaggtcggc gtacgtctcg cgggtgcgca ggatgtcggc ccgggcgagg tagacgaacg
     2041 cgatcatcac gcccgacagg atgagttcgt gcccggtgcc gaggcgttcc gcggggccga
     2101 ggatcgcgga cgacgcggag tccttgaggt cctgcacgat ccggaacagg taggcgggga
     2161 gcacggcgac gaggaagacc cgccagaggg cgaccgtggc gtaggtgacg tcgatgtcgt
     2221 ggttgcggag gtgcgcgagt tcgtggagga ccaccgcgcg gaagccctcc gggtcccggc
     2281 gccggcgggc gaccaggccg ccgtgcaggc agacggtgta gcggcgcagc cgtccgaaga
     2341 ccaccgcgcc ggcggtggcc gcggccggtg ccacgacgaa ccgaggcggg cgggacagcc
     2401 cggcgacgcc gaccagttcg tccaggagcg ggcctaactc cccttcgggg tcgacggctc
     2461 gcagtggtac gacgcggccg cggcggccct tccaacgggg cagcagccag tacacggtgg
     2521 cggccgcgag cagcagggcg gcgaggacgg cgagcggtac ccatgcggcg gcggagggca
     2581 cgtaccggct caggcaggcc gggtaggcgt cgccggcgcg caccgcggcc aggccgatgc
     2641 ccagatagtc gctctccggg tcggcgccgg ccgcgagtgc gcagccgacg cggatgttgc
     2701 gcgggtcggc cagcgcctgg acgatctcgg tcacgatcgt ggcgctgctg gtcaggaaca
     2761 gcaccagcag cagtgcgaag cgcagtccgg tgccggcgcc gaggacgcgc ccgtcgacgg
     2821 gcgggcgggg cggtgcggcc gtggtccggc tcacctgtcg ctccctacgc ctcgggttct
     2881 gcgggcccgt cgcctccggc gtcgttcgcc agccggccct gcgggcgcag caccaggcgc
     2941 gccaccaccc gctcggcgag cgcggtggcg gtttccggcg cgaggccgct ctccgtcccc
     3001 agctccagga cccgcgcgcg caccgcggcc agttgctcct cgctcagcgg ggggagcgtc
     3061 ctggcggccg ccggtctgcg ggtgacccgg cgcagccacc ccttcgtgcg gtccgtcgcg
     3121 ccggtgacgg cggcgccgac gaccttgcgg gccgcctcgt ccagcaccag ccaggccacc
     3181 ggcgtgatca gcgcggtgac ctcctgcagg ccgaagccga gcggctcccg tgcgcggcgg
     3241 cggccggcca ggcgcgccac cacgctgtcg tcgtcgtacc gccagagtcc ttcgaccagc
     3301 accagttcgt ccggggccag ctcggccacg accgaccgga cgacgtcccg caccgccacg
     3361 gctgtccccg gctccggctg cccgtcggcc ggcttcgcca acgcgtccat ccgcccccct
     3421 cacgaacgcc ctctcgccac gcatcgtaag tgcgccgcca cgcgcgcggg cggttttcca
     3481 caggactgtg tccgccgggg cggtcagccg accattccgc gccgttccgc ggcggggttg
     3541 gccgttccgt tgtgcgggtg gggcgggggg tgggcgtgga acagggtggc gtacaggccg
     3601 cgttgggcga ggagctgggg gtgggtgccg gactcgacga gcaggccgtg gtcgaggacc
     3661 agaacgcggt cggcgtccgc ggcgaggtcc aggtcgtggg tgatcacgag ggtggtgcgg
     3721 ccctcggcga ggcggcgcag ggggccgagg atgcgctggg tggcgagcac gtccaggccg
     3781 gtggtgggct cgtcgaggac gaggacgggg gcgtcgcgga gcatggcgcg ggcgatcgcg
     3841 atgcgctgga gctggccgcc ggagaggcgg gcggtgccgg gggcgatgac ggtgtcgtag
     3901 ccgtcgggga gggcggtgat gaagtcgtgg gcgtcggcgg cccgggcggc gcgctccacg
     3961 tcgtggtggg tggcgcggcc gtgcgggcgg ccggcggcga tgttctcctc gacggtgtcg
     4021 tgcaggacga gggtgtcctg gggcagcagc gtgatgttgt gccgcagctg ggcgagcggc
     4081 atgcggtgca cggggacgtc gtcgaggcgg acggtgcccg cgtcggggtc gtagaaccgc
     4141 agcagcagcg cggccagggt cgatttgccg gcgccgctgg ggccggtgat gaccagcagt
     4201 tcgccgggga cggcggtgaa ggagaagtcg tggagggcgt cctcggagcc gccggggtag
     4261 cggaagtgga cgtgccgggc ctccacctcg ccgagggcgc ggccgtggcg cggcggggcg
     4321 accagggagg gcgccgggtc ggtgacggcg gggcgggcgt cgaggatctc caggaggcgc
     4381 tcggcgccgg cggtcgcttc ggtggcggtc aggccgagct ggccgaggga gcggatcggt
     4441 gggtagaggt agccgacgaa ggcggcgaag gcgagcagct ggccgagggt catccggccg
     4501 gcggagatct cccaggcgcc caggccgatg atcgtcagca cgcagacggt ttccaggagc
     4561 tcgacgacct ggtcgtagag cccttggagt cgggcgctgg tcaccgaggc ccggaaccac
     4621 ctgcgcgcct ggtggtcgag ccgttcctcc tcgtcgcgct gccggttgta cgcctgggtc
     4681 agcacgacgt tgaccaggcc ctcctcgacg acggaggtga tggcgccgtc ggcggcgcgc
     4741 tcgcggcggg agacctcttt gacccggccg gtgaagcggt gggtggcggc ccagaacagc
     4801 ggcgccagga cgaaggtggc cagggccagg tcccagcgca gccagagggc ggcaccggcg
     4861 tagaagatga tgccgaagag cgccgcggcc gcctggacga ggccggtgat gagcatctgc
     4921 tcgatggcgt cgacgtcgcc cgtcatccgc tcgacgaggt caccgcggcg gctgcgctgg
     4981 aagaagtgcg gggggagcgt ctggagatgc gcgaagaccc gggcccgcag gcgcatgacg
     5041 aagcgctcgg cggtccaggc cgcgagggag ttgccgaggt agcccaccac cgcgccgacc
     5101 acggcgacgc cgagccacag ggacgcgggc tgccagaagg cgctgaccga gcccttctgc
     5161 agggccttgt cggtgagttg ggcgaagagc aggatggccg cggtctcggc gagggcggcg
     5221 gcgacggcgg ccaggcagac caggaggatc cagcgccggt cgccgtgggt cagtggccag
     5281 aagcggcgga gcgattcctt gagcccgacg cgcctggtgc ggatcgtggg gtccgtctgc
     5341 cggctccaca ggcgggtgtc aacaggcggg gattccgtgc cgggttgggg cgggggcggc
     5401 ggctcctcgg tgggtgccgg ctgcccgcgg gaggtgcgca gatgcatggt caccacgccg
     5461 tatcgggctg ctcggaaacc tggaccggtt cacggcccca agcacacgag gcggactcgc
     5521 gtggcacgcg agccagcctc gagctcagag ctttgggtca gtagaagttg tcgtagccga
     5581 agaagcggcg acggcggcca taacgacggc cgtaccggcg gcgacgccgc ctgcggtcgt
     5641 ggtcgtggtc ccatccgtcc ctgcgcctgc gggggaagac tttccggaag ctcatgctcg
     5701 cctcctagga ttttgttcct tgctgacgag ccgtttccga ctacgtcaac tcccaagcta
     5761 cgtcgacgac ctgcccagca acaaggaaat atgcgtgaaa attcagacaa acaggcaaat
     5821 tcttcgcggg tcacctgagg gtggcgagtc gtaacgcagc gcatacggga cgaccgcggc
     5881 ggcaccggcg gccccgacct gggaaacgtc accctccgta gccgttaggg gacttggtgg
     5941 tccgggttcg gcgcggcagc agcggttacg ggtacgccgc ggaccggccg gtggcgtaga
     6001 ccacgagggc gcccggggcg ccggagagcg gcgcgaggag cccggcgaac ctcccccggc
     6061 cacgccgggt cagggctggc agcgggcgca ccacacggtg ccgcggcccg cgacgcggcc
     6121 gcggcgcagg gggccgccgc agcgcgggca gcgcgggtcg gggtcgtcgc ggcggccggt
     6181 cagccagctg tcgcggggcg gcacgcagcc cgcccgcacc gccgcgcgca gggtgcggcg
     6241 cagctccgtg tgcaggcggt cgccctcctc gtcggtgagg tcgcgggcgg gccgggacgg
     6301 gggcagccgg gtgcgccaga ggatctcgtc gacgaggagg ttgccgagtc cggccagcac
     6361 ggtctggtcc agcaggaccg ccttgaggcg gccgcgccgg ccggcgagcg ccgcccggag
     6421 ggcgccgcgc ggcaccgttg ccgcgtccgg tccgagaccg ccgagcaccc ggtccagccc
     6481 ggccgcgtcg accagccaca ggccctggag tttgcgctgg tcgcggtagc ggagcaggtg
     6541 gtgccggctc atggtgaaga ccacccggtc gtgggggtgg tcggcctcct ccggtgcggt
     6601 gcacaccagc cggccggtca tgccgaagtg cagcagcagg gtggggccgc cggtccgggc
     6661 gatcagccac ttcccgtgcc gctcgggtgc ggcgaacctg cggccctcca gggcgtggcg
     6721 cagctgacgt gcgctcagcc cgtgcagcac gcccgcgtcg cggacctcga tgtgccggac
     6781 cacccgtcgc cgggcgcagc aggcgaaggt ggcgcggaac gcctcgacgt cgggcagctc
     6841 gggcatgccg tccaccgccc tcctggccgt tgtcgcgggg tcggttgtta tccctgaccc
     6901 aggacccggc cgacgaaggc cgccagttgg gccctcatcc gcgcgggggc ggtgccctcc
     6961 tcgccggcga ggtgctcgac gaggtcggcc cgggtggcgg ccagcagggc gtgcgcggtg
     7021 aagtcggcgt cctcgtgacc gggcagccgg cgcagggtgt cccgcaaggt gccgtgccac
     7081 caggcgtagt gggccgcctg atacgggctg ccgctgccgg cctcctccag ggcgagggac
     7141 aggtggcggt tctcaagctt gaagcggagc agcgcgtcga gcagcgccgg gacccgttcg
     7201 cgcggcgggg tggcggggcc gagcggtgcc ggtccgtcgg tcacggccgt ccgcagcggc
     7261 tcgatccgcg cctcgaagac cgcgcggatg aggccggtgc ggtcgccgaa gcggcggaag
     7321 agggtgccct tgccgacgcc ggcggccgcg gcgatctcgt ccatcgacac ggtgcggggg
     7381 ctcgcgctgc gggcgaagag ttcgtcggcc gcggccagga cggtctcccg gttgcgcaac
     7441 gcgtcggccc gcgccttgcg ttcggccatg ggtgagaccc cctttacgaa acggaccgtc
     7501 ggtccgtata gtccacaacg gttaagcgga ccgatggtcc acatcgttcg cacagtctag
     7561 aggcgaggca tccccatgcg tgaaaccgac ccggcggcgc tctatcgcca cggcctgcgg
     7621 ctgctcctgg agaaggacat ggagggctgg gtcgccctct gcgccgacga cgcggtcctc
     7681 gaattcccct tcgcacccga gggctacccc cggcggctgg cggggcgggc ggagatcgcc
     7741 gcgtacctgc gggactaccc cgaccacatc gatctccggg ccgtccccca cctgaagatc
     7801 caccgcaccg acgccccgga caccgtcgtc gtcgagatgc gcgccaccgg gcggatcgtg
     7861 gccaccggcg cgccgtacga gatgacctat gtcgtcgtgg tgaccgtcgc cgacggccgc
     7921 atcacgcact accgcgacta ctggaacccg ctcgccgtcc ccgcctccat gagcgaggcg
     7981 aaggccggat gaacgaccgt gacaccgtcc tggtcaccgg ggccaccggc accaccggca
     8041 gccgcgtcgt cgcccggctc gccgcgctcg gacaccccgt cagggccgcc gcccgccgcc
     8101 cggacggcgc ccgcgccgtc cccttcgact ggtacgaccc ggccacccac cccggcgccc
     8161 tgcacggggc ggaccgcctg tacctggtcc cgccgcccgg cgacccggac ccggccgccg
     8221 tgatgcttcc cttcctggag cgggcccgcg cggccggggc gcgccgcgcc gtcctgctga
     8281 gctcctccgc gctgcccgcc ggcggcccgg gcgtcggccg ggtgcacgcc gcgctgcccg
     8341 gcctcttcga cgcgtggacg gtgctccgcc cctcctggtt catgcagaac ttcaccggcg
     8401 gccatccgca cgcacaggac ctccgcgagc gcggcgtcct cacgaccgcc accggcggcg
     8461 gccgggtcgg cttcgtcgac gcggacgaca tcgccgccgt ggccgtccgc gccctgaccg
     8521 ccgaaccggc cctccccgcc ggcgatctgg tgctcaccgg cccgcaggcc ctgtcgtacg
     8581 acgaggtcgc cgccgtcgtc agcgaggtca ccggccggcc ggtacgccac cgggccatcg
     8641 gccacgaggc actgcgcgac cggctggccg ccgggatgcc cgcggagttc gccgcgctgc
     8701 tggccgggct ggaccgcgcg atcgccggcg gcgccgagga ccgggtgacc gacaccgtgc
     8761 agcgcctgac cgggcgcccg ccgcgcgcct tccgcacgca cgcgcaggcc cactggtccg
     8821 gcggggccgc ccgcatcccg acgccgtgag gcggcccctc tttgcgcacc ggccgtgccc
     8881 gatggcgcgg acgccggggt cgacaccgtt cggctccgcc cggcgggcga cgcgcttcag
     8941 gagcgcttgg acaccttggg gcgggcgctc gacttggtgg gtgagctgga cgacggccgg
     9001 gcgacgcgcc gggggcgggc gctcgacttg ggggcgacgg aggacggccg ggccacgcgc
     9061 cggggggcgg cggcaccctc ggagttgacg gggtccgagg cgccggccgg tgcggggagg
     9121 gtgctggggt caccggggtc cgaggagcgg gccgggtcct gcgggtcgcg gcggtccggg
     9181 gagtcgccgg tgtcccgcgc gtcgcccggg tccaggtggt cgtcggagtc ccgggggtca
     9241 cgggaatcac cggggtcacg gtcgcgcccc gggtcacggg agtcggacgg atcgttgtag
     9301 tcaccggggt cgcgggagtc cccggagtcg cgccggtcgg acgggtcccg gtaatcgccc
     9361 gggtcacggg agtccccggg gtcacgggag tcggagggat cgcggtagtc gccggggtca
     9421 cgggagtccc ccgggtcgcg ggcgtcctcc cggtcgcggg attcgtcggg atacgacggc
     9481 gcgggcgcgc tggccgggtc cagccgcagg ctgccgtacc gcgcgaaccg cgccgagctg
     9541 ccggcccgta cggtcgccat cgagcgcccc gtgcagtcgc gggaggacca cagcaccagg
     9601 tcgagggggg tgtcgttgtc caccaggccg cccccgtcac ccaggccgta gcagtgatcg
     9661 tctccggggt cgacgatctg gtagtccttg ttccgcgagc gcatgtggaa ggtgatggtg
     9721 ccggtggtgg cctgggcggc gatcgggccg agcagggcga aggcaccggt ggcggccacg
     9781 gctccgagga aggcggtctt gtgtcgcatg acgccaaggt tcccgacgac atatcgggct
     9841 attcacctcg aaacggatat tcacccatcg ccgcgtgccg cactccccgg acacagcacc
     9901 tcccgcgccc tcgccaccgc cgcggaaagc tgacggcgag ccagttcgtc gcgctcccgg
     9961 ccgccgtcgc ccccccacgc gcctcacggg cccgtcggtg tcatccgacg cgcgcgaccg
    10021 gccgctggaa gaaccgggcc gccgacgtcc ccagccccga cggcgcgccg agccggcccg
    10081 gcgagcccac cgggtggcgc agctccggct cgatgtagcg ccggcagccc cggtgccagt
    10141 tgaggatgcc cgccatccag ttctccagct cccggacatg gccgtcgagc gcggcgcggg
    10201 cctcggccga cagctggaag tcgtcgcaca cgaccgggag ttccttcgcg acgaggtgct
    10261 ggaactcgcg catgcgggag gtcatgaggt cgtggacgat ggccagcgcg gtcgggtagt
    10321 cgcagtcgaa gaaggtctgg acgaccagga tgccgttgtg cacctcgccc tcgtactcga
    10381 tctccttctg gtaggagaag acgtcgttca gcaggcaggc gaagtcggcg gcggagttct
    10441 ccagcgcgcg cagggtgccg gtgcggtaga cctccggcgg gacctgccgg ccgtggccga
    10501 tgcggctgag ggccatggtg aggtcggagc cgaaggtggc ccggcgcatc tcgatgtagt
    10561 cgaccgggtc cgggacgcgg tgctggatct ggttgtcgat ctcccagagc caggcggcgg
    10621 tcatcgtgtc gacggccgcg cggaaaccgc ggcgtgcctc gggcgccatc gcgcgggtcg
    10681 tacggggcca caggtcggcc agcccgcgct ccatcgcgtt gaccggctcg ggcggggtcg
    10741 tcgcggggtc gagcggcatg aagagcttca gccgttcggt gcacgcgtgg gccgcggcgg
    10801 cgtcccgggt ccggccgaag acctgcgggt agtagtcgtc cgcgtaggtg ccccacgcca
    10861 gccaggcggc gccgaggtcg agctggtcgg gggtggcgtc cgggtggagt ccggccgcgc
    10921 acagcgccag gtcgtgccgg accatcgccg cctcgtccca gacgtcggag agcggcacgc
    10981 cgggctgcgg ctggagcatg cccatccggc cggcccacgc gacgacccgg cggcgggcgc
    11041 cgtccaggtg cgggctgagg gtgagcggga acggcatgcg gatgtcggga atccgcgagg
    11101 gcccgacctg ctggtgcggt acgtgggtgt ggctgcggag gcggtgcgcg ccggccgtcg
    11161 ccagggcctt cctgaggtcc gtggccgagg tgccgaggcc gccggcggag aacggcgacc
    11221 agggccgtgc ggaaccggcc gccgccccgc cgtcgttcat gtagcggctg gagcgcaggt
    11281 gccattcgtg accgccggac tgccagtcct gcagcccctt ggcgtacgcg aggacgtccg
    11341 cgcaggactt cgggtcgagc cccttctcca ggaagagcgc ggggagttcg gtgaccacgg
    11401 tgttctcgaa ctgctggagc cgtgaggtga tcaggtcgtt gacggcgtcc gcggcctcct
    11461 gggtggtgca gtccaggaag gtctccagga ccagcacgcc gttgctcagc tcgccttcct
    11521 cttcggtctc ccgctggtag gagaagaggt cgttgcgcag gtggacaccg tcggagaagg
    11581 tgtcgcgcag cacccgcagg ggccgggagc cggccacccg cgccgggacc tcggccccgg
    11641 tcgcgtactc caccagcccg gccgaccagg gcgcgccgcc gaccttgcgg cgcatctcga
    11701 tgtactcgac ggggttgggc acccggttga tgttgatgtt ggacagttcc cacagcgatt
    11761 cgttgagcag gtgctcggtg ctctcggcga accggcggcg ccagtccgcc gacatgtgcg
    11821 gcacggtgcg cgcccacagg tcggcgagtc ccgcctcgac cgggttggcc ggctcgggca
    11881 ccggcgcgcc ggggtccgtc ggcatgaagg cgggcagccg gtcgaggtac tccttgccgc
    11941 ccgcgcggtc cagcgtccgc ttgaacttct ccaggaagtg gtcgtcgaag aagaagaccc
    12001 agacgtacca gtcggtgacg agcgacagcg cctcggcgtc gcagtcgggg tgggtgtagg
    12061 cgcagagcag ggcatagtcg tgggcgtcga ggtcccgctc gtcccagatg ccggagccct
    12121 ccagcatccc catggcgcgg gcccacttcc tggagtgcgt ccgcgccgct tccaggtgcg
    12181 ggttgagccg cgccgggtgg ggcgtgtaga agtcgggcag ttcgaatggc ttggtcaccg
    12241 tgctggcctc tccccatacg tgcggaggaa ggcgtgctga accacgcccc ctgacggggg
    12301 cagcgctacc ccgggggttg ccgcactaga ccttacggag gaggggcttc cgtttctccg
    12361 ccgtttccgc tcggccggtg ccgcccattg atcattcggg gccgctttcc gacgcccttc
    12421 ttccggctcg cgcccctgta cgcagggcga gttccgccag tgcctccggg gcgccggcct
    12481 gaccgcggat gccggggaaa gcgttgacgt cgaccaggag cggggcggcg ccgccggcgt
    12541 cgaggaagtc cacgccgtag acctccaggc cgaagacctc gcccgcccgc agcgcgaggg
    12601 cccgccagtc cgccggcagt tcgccgggcg gcagcggcag cgtccccccg cggccctccg
    12661 gggccagttc ggagcggcgc agcccggcga acagctgccc gtcgaccacc cacaccttgt
    12721 ggtcccagcc gctgcccgcg aggaagtcct ggacgaccac gggttcgccg ggccactcgg
    12781 cggccagctc ccgcagccgt acggcgctgt cggcgcgggc caccaggtcg ccgcgccggc
    12841 tgtgccggct cttgacgacc agcgggccgg ccggctcgcc ggccgcggcc agctccgccg
    12901 gtgtccccac gaagcgggtg cgggcgaacg gcagtccggc gccccgggcc agttcggcca
    12961 tcgccacccg gtcctggcaa cgggcggtcg ccgccgcgga gttgacgacc gcggcgccgc
    13021 gctcctccag gcgggcggcg aggaccagcg cccggggcgt gcgggccttg aggaggtaga
    13081 cgtcggcgag cggtccgggg tcctcgtgcc cgccgccggg gtccacgacc tcgacccggt
    13141 ggccgccttg gagcagcagg gcgccggtcg cggccagcac cgggtgggcg gcgtccgcgg
    13201 tgatcaggcc gatcctcacc ggtcgccgcc gatcgccgcc agcgggggca cggcgggggc
    13261 ggccgggccg gggaccgccg gttccgctcc cttgcgggcg agccgcagca cggcggagga
    13321 cacccgggcg acggcgtccg gcacctgacg gaagctgggg aagtcgttga tgtcgacgac
    13381 caccgggccg tccggtccga gcaggacgtc gacgccgtac aggtcgaggc cgaagaccgt
    13441 gccgatctcc gcggtgatcc gggcgacctc ggcagtcagc gggacctggc gctcccgtac
    13501 ggcgtgcccg gggtgcagcg gggagcggcg ctcggtcgcg tagagctcac cggcgacgca
    13561 gtacaccttc aggtccgtac cggagttggg cacgtacggc tgggcgatca gcagtccgcc
    13621 ggccgccccg cccggctccg cgggctccgc cgcgccggcg gcgggcagcc ggtccggcga
    13681 ctcgaccagc cggaccgcgc gcccggagct gccgtccgcg ggcttgacga cgagggggaa
    13741 ctccgcctcg ggtatctggg cgaactcctc ggcccgggcg gccgcgtagg tcaccggtac
    13801 cggcagtccg ctgccgcggg cgatcaccgc ggccagcgcc ttgtcgcgca ccccccggat
    13861 cgcccggacg tcgttcaccg tcgtcagccc gaccgcggcc gccgcttcca ggaggctcag
    13921 gccggggccg ccggagacgg tcttgagcac ccaggcgtca tggctgcccg cgcgcaccgc
    13981 ctcggacagc ggcagcagcg agcggcccgg ccacatcacg tccacctggt gcccccaggc
    14041 ggtgagttgg cggatcacgt ccagcggcat gccgtcgtag cggtactgct cctccaccag
    14101 gaagcagagt ctcatcgggg caccctcgtc atcgccgcac gtccgtccac cgtccgtccg
    14161 gcagatccat gacgcaccag gatcccacgg ggggccgggc ggggcggggc ggacccgcgc
    14221 gcccggctcc ccgtccgtca gccgccccat gtttccgcgg tgttacgcca cccggcgccg
    14281 cccgagcacc cgctctgacc aggcacgcct ccagggcgcg gcggagctcc gccacccgca
    14341 cccgcgcctt gcgaatcccg catgccggaa cccttgttcc acttccgggc cggtcctagg
    14401 gtcaggccac cccggggacg gtccagcaaa gaggtactca cgtaccgcag tacgggaagc
    14461 aggcgagcgg gttggcgaac gaacagcaca gcggcttcgg acggcgcgga ttcctggccg
    14521 gcgtgggcgg attcgtcggt gcctccggca tcggtgcccc cggcgccgcc gcggccgaca
    14581 ccccccaccg gggcccgcgg ctcacggact tccacggcag ccggcacctg ttggtcccgg
    14641 agctgctgct cctgccggag gggccggccc gcggccgggc cgtactggtg gacggcggga
    14701 agttccgcgc cgtcggcccc gccgaacaac tcctcgccgc ccaccgggac ctgcggcccg
    14761 tccggctgga cggccatctg ctgatgcccg gcttcgtcga cgcccatcac catctgaccc
    14821 agagcttcgg caaggcgcag tccttcggcc agccgtcgga gatcttcaag acggtgtggg
    14881 agccgctgga gcacgcgctg gacgaggaga gcgcctacgt ctcggcgaaa ctggccgcgc
    14941 tggaggcgct gcgcggcggc ttcaccaccg tcgccgatgc cggcacccgg gcccccgtcg
    15001 acgtccgggc ggtcgcgaag ggcaccgagg aggccgggat ccgctgcgtc ctgggcaaga
    15061 tcgtctcgtc cggtaccggc ggcccggagc acctcgggcg ctgggagggg cacccgctgg
    15121 tccacccctc gctggccatc gccgtccccg aggacgcgcc cgccgacgtc ctcaggaaga
    15181 ccgccgacct gtgcgccgag gccggtgcgg tgctccaggt ccacgtcaac gaacatctgg
    15241 cgtccgtgga gcgctcgttg aagagcaccg gccgccgccc gctggagtac ctgcaccaca
    15301 tcggtgccct cgggccgcac accctgggcg cgcacgccac cctgctcacc ccctccgaga
    15361 cccggctgct ggccgactcc ggtgccgccg tcagctacaa cccggtcgcc agcgcctgga
    15421 agggcaacgg cgtggcgcac gcgaccctgc tcgccacgct gggtgtgcgc ttcggcatgg
    15481 gcaccgacgg cacccgcggc gacggcttcc ggctgatcga cgccggggag accgcccagc
    15541 ggctggcgta cgggatggcg gcgggcgact cggtgtgcgg ggccgggcgg acgtggctgg
    15601 agcacgcgac gtcgggcagc gccgacgcgc tcggcctggg cggggtgacc ggtgagatcg
    15661 cggccggcaa ggccgccgac ttcctcgtcg tgaacctcga cgtccccgag ctgacgccct
    15721 cctacgacct gcgctgggaa ctcgtccggc tggcgaaccg cgaccagatc gccgcggtcg
    15781 tcgtcggcgg gaagctccgc ctgtggcacg gctggccgac ggactgggac ggcccggcgc
    15841 tggtggctcg ggccgcggaa ctgggcccgg aggtcgtccg ccgggccggg atccagcggg
    15901 tggagccggt gtaggtcggg ttccgcggcg cggtcggggc cggcccgcct accgccgcgg
    15961 acggccgggt gcggtgtccg gggccgggcg ccgtcggccg gcaccacggg tgcgtgaccg
    16021 gtccggcgga atccaccggg cgacgagcag cgccacgacg gtgaccaccg cggccagcgt
    16081 cagggtcgcg gtgtgcagcc cggcggtgaa cgcgtcgacg accgccgcgc gcatccgcgg
    16141 gccggagctg ccggcctcgg ccgccgccac cgtcgtcggc ccgccgggac cggacagcgc
    16201 cgcgggcagg cgggcggtga acaccgcggt ggtcagggtg ccggtcacgg cgatgcccag
    16261 cgcgctgccc acctccctgg ccaggctctg cagcccggac ccggccccgg cccgctcggg
    16321 cggcagcgcc gccatcatgg cgtgcgagag cagcggggtg gcgaggccgc agccgagcgc
    16381 ggtcagcccg gcccccaggg cgtaccgggc gtacggggtg tgcgcgtcgg cggtggagac
    16441 cgtgccgagc ccggcggcca gcaccagcat ccccgtcacg accgtgcccc gccgcccgca
    16501 ccgccgctcc atcagcagcc cgcagcgcgg cccggccagc agcgccgccg ccatcggcag
    16561 cagccgcagt cccgccccga acgggccgtg gcccttggcg tactggaggt actggccgtt
    16621 gaggtagaag agcccgaaca tgccggtgaa cagggcggcc atgcccagcg cgcccgcgcg
    16681 cacggcgggc cgggcgaaca gccgagggtc caacagcggc cgctccgcgc gcagttcgca
    16741 gcgcacccac ccggtcagca gcagcgccgc ggcgccgagc gacccgagcg cggccgggct
    16801 ccgccacccc tcctccgggc cgctgaccag cccgtacagc agggccagga agcccccggt
    16861 gagcagcgcg ctgccgagcg gtgcgaccgg ccgcgggtgc cgggcaccga ccggtgcgac
    16921 caccccggcc aggaccagtg ccgccagtgc cggcggcacc gcgcacccga acagggtccg
    16981 ccagccgccg tactcgacgg ccgccccgcc gccgacgttg ccgagcaccg cggcgagccc
    17041 ggtcatcgac gcccaccccg cgaccgcccg gcgccgcgac cgctcgtcgc gcccctccac
    17101 cagcagcgcg agcgtggtgg gcagcaccgc ggcggccccc gccccgctga tcatccgccc
    17161 ggcgatcagc accccggcac cgggcgccag cgcgcagacg gcacagccgg ccgtgaagac
    17221 ccccgtgccg cacagcagca cgcccttgcg gccccgccgg tcggcgagcg caccggccgg
    17281 caccagcaga caggcgaaga ccaccacata gccgtccacg acccagacca gcgcctgtgc
    17341 ggaggggtgc agcgcgctcg ccgccagggt gggcagggcg aggttgacgg ccgagaccat
    17401 gccgacgacc agggtgacgc acaggcacat cgcgagcgtc agcgcgccgc gcggcgctcc
    17461 cggtaccgcg gcggccgcgc cgactccctc acgtgacagg gaggtcggcg acatgccggg
    17521 cggcccggtc gagggtggcg tgcagggtca gccggtcccc gcgcagatgg atgaactcca
    17581 ggtcggctgg gcgcccgtcg gcgagccggg tgaggcgctc gacggcgagg accgcgccgc
    17641 cctcgggcat cgcgagcacc gcgcaggtcg ccgggtcggc caccacggcc tggacggaca
    17701 cctccgcccg gcccagcggc gcgcccgcca cccgctcgat caggccgaag acgtcgtgcc
    17761 gttccagcgt ctcccggccg cgggccagca gcggctcccc gacctccggg atgaggtacg
    17821 tgcagtccag ggacagcggc cggccgtcca cccgccgcag ccgctccaga tagaccgccg
    17881 gggtgccgtc cgccaggccc agccgccggg cgaccgtcag cggcggccgt acggtgcgcg
    17941 cctcccgcac ctcgttgacg accgtgccgt gccgttgcag cacctcggcc agcccggaca
    18001 gttcgccgag cgggtgctga taggcccggc cgacgacgac cgtgcccacg ccccgccggc
    18061 gcgccaccag cccctcgtcc cggagcagcc cgagggcctc ccgcacggtg ttgcgcgagg
    18121 tgccgaactc ggcgaccagg gcccgttcgt ccggcagcac cccgtccgcg aaggcgccgc
    18181 gcagcacctg cccgcgcagc acgttcgcca cccgccgggc ccggtccgcc cgggtgagcc
    18241 cgtcgccggc cccgtcgtcc ctcaccgtcg cacgctgcac ggcccggcct cctcaccttc
    18301 gccagcgggg caccgacgct aggcgagcgg tgttgcggcg acgttacgcc accccctgtg
    18361 acctgcacag atgtctgaac tgggggtttg cgcggcaggg cgggggatac gccaccggcg
    18421 ggccggctac cgctaacgtg aggcgaccgc gacgccagcg gcacctggat gagaacggga
    18481 ggtccgttga cccacaaggc cgtgcccttc gacgagctcg accgcaagat cgtcgcggca
    18541 ctgatcgaca acggccgggc gagcttcgcg gagatcggga cggccgtcgg gctgtcgtcg
    18601 accgcggtca aacggcgggt ggaccggctg cgggagacca acgtcatcac cggcttcacc
    18661 gcgaccgtcc ggccggccgc gctgggctgg ctgaccgagg cgtacgtcga ggtgtactgc
    18721 gacagcgcgg cgccgccccg gcggctggcc gaagtggtgc gcaaccatcc ggagatcgcc
    18781 gccgcgatga ccgtcaccgg gggcgcggac gcgctgctgc acgtgcgggc gaccgacgtc
    18841 gagcacttcg aagaggtgct ggagcggatc aggacggagc cgttcatccg caagacgatc
    18901 agttacatgg tgctgtccca tctgctgccg gacagcccgg aggcgggcgg ccggggtcac
    18961 gcgaccggat ccgacgcagg aaagcagcgc tgacctgcgc ttctccgcag cattcgtgcg
    19021 ccactgagca gcgtttgttt cttgtggccg gaatgcgtcc ttcctaccgt tgagacaccg
    19081 cgggtcacga ccggtgacag ctggtcaccc cgcatgtccc cagaggaacg tgtcctcaca
    19141 aggaagcgga gggggtactc ctgtgccgac gagtcgtgtg gcgagtccac ggcgttttct
    19201 ggtctgcgag cccgagcact tcgaggtgcg ctacgccatc aatccgtgga tgcgggcgga
    19261 ggtgccggtc gacacggcac gcgcggcccg gcagtggtcc acgctgatcg agacctaccg
    19321 cgcccacggg cacgcggtgg agtccgtgcc gccggtcccc ggcctgccgg acatggtctt
    19381 cgcggcgaac tgcgcggtgg tgatgcgcgg ccgggtcttc ggctcgctgt tccacgcgcc
    19441 ggagcggcgg ccggagtcca ccgcctacga gacgtggttc aaggccgccg ggttcgacgt
    19501 ctaccgcccg gaatcggtgt gcgagggcga gggcgacctg gtcccggcgg gccgcttcct
    19561 gctggccggc accggcttcc gtacggcgcg ggccgcgcac cacgaggcgc aggagttctt
    19621 cggcgtcccg accatcggcc tccagctggt ggatccgcac ttctaccacc tcgacaccgc
    19681 gctgttcgcc ctcgacgagg agaacgtggc gtactacccc gacgcgttct cgcccgggtg
    19741 ccgggaggtg ctcgcgcggc tcttccccga cgcggtgctc gcgacccgcg aggacgccat
    19801 ggcgttcggc ctcaactcgg tctccgacgg ccggcacgtc ttcatcgccc cgcaggccac
    19861 cggcctgatc gaccagctca ccgaccgcgg ctacgtcccc gtccccgtcg acctctcgga
    19921 gttccacaag gccggcggcg gcatcaagtg ctgcacccag gagatccgct catgactgct
    19981 cccacccgta ccgccgtcgt cggcgcgccc cgttcgtccg ccgagctgat ccaggccgag
    20041 gccccggtcc tggcgcacaa ctaccacccg ctgccggtgg tcgtggcgcg cgccgagggc
    20101 gtctgggtcg aggacgtcga gggccgccgc tacctcgaca tgctggccgg ctactcggcg
    20161 ctcaacttcg gccaccggca cccggacctg atcgaggccg cgcaccgcca gctcgaccag
    20221 ctgaccctga cctcgcgcgc cttccacaac gaccggctcg ccgggttcgc cgagggcctg
    20281 gccgcgctga ccggcctgga catggtgctg ccgatgaaca ccggggccga ggcggtcgag
    20341 agcggcatca aggtggcccg caagtgggcg tacgacgtca agggcgtccc cacggaccgg
    20401 gcgacgatcg tggtggccgg cggcaacttc cacgggcgta cgacgaccat cgtcggcttc
    20461 tccgacgacg acaccgcccg cgtcggcttc ggcccgttcg cccccggctt ccgcaccgtc
    20521 ccctacaacg acctcgccgc gctcgaagcg gccgtggacg agaccacggc cgcggtgctg
    20581 atcgagccca tccagggcga ggcgggcgtg ctgatccccg acgacggtta cctcaccggc
    20641 gtccgcgaac tgacccgccg cgccggctgc ctcttcatcg ccgacgagat ccagtccggg
    20701 ctcggccgca ccggcacgac cctggccgtc gagtacgagt ccgtcgtccc cgacgtgctg
    20761 ctgctcggca aggcgctggg cggcggcatc gtcccggtct ccgcggtcgt cgcccggcgc
    20821 gacgtactgg gcgtgctcgg ccccggccag cacggctcca cgttcggcgg caacccgctg
    20881 gcggcggcgg tcggttcggc cgtcatcggc ctgctggcca ccggggagtt ccagcgccgg
    20941 gcggccgaac ggggcgagca gctgcgcgcc ggcctggcgg cgctgaccgg caagggcgtg
    21001 accggtttcc gggcccgcgg cctgtgggcc ggtgtggacg tcgaccccgc cctcggcacc
    21061 ggccgggaga tcagcgaacg cctcctcaag gagggcgtgc tggtcaagga cacccacggc
    21121 tcgacgatcc ggctcgcccc gccgctgacc atcaccgagg aggaactggc ctcggcgctg
    21181 gcctccttgg agcgggtact gggctgagca tcccggagtc gtgacaggcg agtgggccgg
    21241 agcggaccca ctcgccttcc gcgtcccatg aggagcaatt cattccgcat tcccggcgga
    21301 attccagcgt ccacatcttt tcttcctttg acgcgccact gaattgatgg cgtgttaatc
    21361 ttcgggcgcg gtcagcacgg gggaagaacg cacggtcgca ctttcgcttt cacatgggtg
    21421 ccggctgtgc cctgaccgcc tttctccgag gccgcgtaac gcttccggga cgatcgcgcc
    21481 cggaagcctc cgagaatggg ggaattacac gtgaagaaag tcggtatgtc cttggccggc
    21541 gccgcactga gcggcgtgct cgcgctctcc gcggccaccc cggcgctcgc cggccccgcg
    21601 cacccggacg gctccacggt gcgtacgtcc gccgccacgg ctgaccacca ggcggcggcg
    21661 atcagcaagg cgcagaagct caagcggctc aaccagctga ccgagaagta cggcatgccc
    21721 ctctgggaga acacccgcgt caagtggcag gacgggcacg acgcgtacca cttcgactgg
    21781 tcgaccgacg gctgttccca cgtcagcgac aaccccggcg gtttccactt ctgggagtcc
    21841 tgcgcccggc acgatttcgg ttaccgcaat tacaagaaga tgcatgaatt cacccgtgcg
    21901 cacaagaagc gggtggacga ctccttcctc caggacatgc agaaccagtg caggaggcag
    21961 tggggcccgt acaccgaatt gcagcgcaag ggctgcctga aggtcgccaa gaagtactac
    22021 gacgcggtcc gcaccctggg ccacctccag taaccgtccc gacctgaccc ggggccggcg
    22081 gacgaccggc ccggatccgg cggcggtggt gcgtcacgcc tcgcgtgcgc ccgccgccgc
    22141 cagcaggctt tccgccgcgg tacgggcgtg ccgggcggcc gcggggtcgc cggtgagcgc
    22201 cgcggtgctg atcgccccgt cgacgagcag cgccaact
//
