LOCUS       NZ_CP017157            22603 bp    DNA     linear   CON 31-MAY-2024
DEFINITION  Streptomyces lydicus strain 103 chromosome, complete genome.
ACCESSION   NZ_CP017157
VERSION     NZ_CP017157.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces lydicus
  ORGANISM  Streptomyces lydicus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8201357)
  AUTHORS   Jia,N., Ding,M.-Z., Gao,F. and Yuan,Y.-J.
  TITLE     Complete genome sequencing of Streptomyces lydicus 103 and metabolic
            pathways analysis of antibiotic biosynthesis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8201357)
  AUTHORS   Jia,N., Ding,M.-Z., Gao,F. and Yuan,Y.-J.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2016) Key Laboratory of Systems Bioengineering
            (Ministry of Education), Tianjin University, Tianjin 300072, PR
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 100x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001729485.1-RS_2024_05_31
            Annotation Date                   :: 05/31/2024 02:23:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,288
            CDSs (total)                      :: 7,195
            Genes (coding)                    :: 7,061
            CDSs (with protein)               :: 7,061
            Genes (RNA)                       :: 93
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 47 of 134
            Pseudo Genes (incomplete)         :: 104 of 134
            Pseudo Genes (internal stop)      :: 11 of 134
            Pseudo Genes (multiple problems)  :: 26 of 134
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:52:31
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1043431
            Orig. end                         :: 1066034
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017157.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Source DNA is available from Prof. Ying-Jin Yuan.
            Annotation modified by submitter.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22603
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="4"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22603
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22603
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12603](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12603)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(700..715)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            783..1889
                     /gene="prfB"
                     /locus_tag="SL103_RS04475"
                     /old_locus_tag="SL103_04475"
     CDS             783..1889
                     /codon_start=1
                     /gene="prfB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000796.1"
                     /locus_tag="SL103_RS04475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_04475"
                     /product="peptide chain release factor 2"
                     /protein_id="WP_069567473.1"
                     /transl_table=11
                     /translation="MAVVDVSEELKSLSSTMGSIEAVLDLDKMRADIAVLEEQAAAPSL
                     WDDPESAQKVTSQLSYLQGQLRRAEELRGRVDDLEVLFELADAEGDEDARAEAETELTD
                     VRKAVEELEVRTLLSGEYDSREALVNIRAEAGGVDAADFAEKLQRMYLRWAERHGYKTE
                     LYETSYAEEAGIKSTTFAVNVPYAYGTLSVEQGTHRLVRISPFDNQGRRQTSFAGVEVL
                     PVVEQTDHIEIDESDLRVDVYRSSGPGGQGVNTTDSAVRLTHIPTGIVVSCQNERSQIQ
                     NKATAMNVLQAKLLERRRQEEQAKMDALKGDGGNSWGNQMRSYVLHPYQMVKDLRTEFE
                     VGNPQAVLDGDIDGFLEAGIRWRKQQEK"
     misc_feature    1963..1979
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.89"
                     /tool="antismash"
     gene            2218..3063
                     /locus_tag="SL103_RS04480"
                     /old_locus_tag="SL103_04480"
     CDS             2218..3063
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605292.1"
                     /locus_tag="SL103_RS04480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_04480"
                     /product="hypothetical protein"
                     /protein_id="WP_069567474.1"
                     /transl_table=11
                     /translation="MTKKTRLRVARIAAGAVIAAGASLTAAGVASAAPADGTGGESGGI
                     IGGLLGGVLGGGDSGGDSSGGDTTGGDTTGGDTAGQVGGGEIGGDSGGEIGGDQTGGET
                     TGGDTTTGGETTGGQTTGGETTGGDTTTGGQTTGGQTTGGQTTGGETTGGHNSGGQSTG
                     GDSTGGHNSGGQSTGGGNGGNGGNGGPSGGTTTGGDSTGTGTDNEGSKPVEQPGQGKEQ
                     IADTPGQAKQQAKGGELAETGSSGTTFLLIGAATMIAGGVGFRVLPRLINKNGGGAAAA
                     "
     gene            complement(3182..3376)
                     /locus_tag="SL103_RS04485"
                     /old_locus_tag="SL103_04485"
     CDS             complement(3182..3376)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018555947.1"
                     /locus_tag="SL103_RS04485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_04485"
                     /product="hypothetical protein"
                     /protein_id="WP_069567475.1"
                     /transl_table=11
                     /translation="MTYDRLVCANCAAPVSEGRCPVCRASRERLQQQAGGVFAQLSPVM
                     LVALMIVLIAVGVLLHQAV"
     misc_feature    complement(3482..3495)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.13"
                     /tool="antismash"
     misc_feature    3553..3566
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.94"
                     /tool="antismash"
     gene            3628..4317
                     /gene="ftsE"
                     /locus_tag="SL103_RS04490"
                     /old_locus_tag="SL103_04490"
     CDS             3628..4317
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /gene="ftsE"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006349025.1"
                     /locus_tag="SL103_RS04490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_04490"
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="WP_069567476.1"
                     /transl_table=11
                     /translation="MIRFDNVSKTYPKQNRPALRDVSLEIERGEFVFLVGSSGSGKSTF
                     LRLLLREERASHGHVHVLGKDLGKLSNWKVPQMRRQVGTVFQDFRLLPNKTVGENVAFA
                     LEVIGKPRGQIRKTVPEVLDLVGLGGKEDRMPGELSGGEQQRVAIARAFVNRPMLLIAD
                     EPTGNLDPQTSVGIMKLLDRINRTGTTVVMATHDQQIVDQMRKRVMELEKGRLVRDQSR
                     GVYGYQH"
     gene            4327..5238
                     /gene="ftsX"
                     /locus_tag="SL103_RS04495"
                     /old_locus_tag="SL103_04495"
     CDS             4327..5238
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene="ftsX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572291.1"
                     /locus_tag="SL103_RS04495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_04495"
                     /product="permease-like cell division protein FtsX"
                     /protein_id="WP_069567477.1"
                     /transl_table=11
                     /translation="MRAQFVLSEIGVGLRRNLTMTFAVIVSVALSLGLFGASLLMRDQV
                     STMKGYWYDKVNVSIFFCNKNDAETGANCAKGAATQQQKNDIKAELDRLPIVQSVTHES
                     SDQAYKHYKEQFGDTPVAGLVTPDQLPESFRVKLKDPTKFTVIKSAFSERPGVQEVQDQ
                     RDTVEPLFNLLNGMNIAALCVMGLMLVVALMLIVNTVRVSAFSRRRETGIMRLVGASSF
                     YIQMPFILEAAIAGLLGAAFACVLIVGGKYVLVNNWLAKKIQVINFIGWDSVAAVLPLV
                     LLIGLLMPALAAFFALRKYLKV"
     gene            5307..6527
                     /locus_tag="SL103_RS04500"
                     /old_locus_tag="SL103_04500"
     CDS             5307..6527
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S41"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572290.1"
                     /locus_tag="SL103_RS04500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_04500"
                     /product="S41 family peptidase"
                     /protein_id="WP_069567478.1"
                     /sec_met_domain="Peptidase_S41 (E-value: 2.4e-40, bitscore:
                     136.5, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGPCSYVRPRRIRRGAALTLFLASVLATGAVTGTWSDEAAGAGG
                     RAAPDHAVPRAHGSASARSSATADRAAVERAATEAVEDGKSGSQAAADVVSRSGDRWSS
                     IYTPGEFEDFQAQLDGRYVGVGLWVRQVGDRTEVSRVRPGSPAAGAGVAVGDLLRAVDG
                     RATRGRPVTETVAALRGDTRRGSRTAVGTAVRLDLQRGDRRWSVTLHRVRLRTRNVVTD
                     RPAGPHGPTRVKIASFARGTGDAVRRAVRRASPHGGLLLDLRGNTGGLVTEAVATASAF
                     LDGGLVATYDMRGAQRALYAARGGNTRLPLVVLVDGGTMSAAELLTGALQDRGRAVVVG
                     SPTFGKGSVQMPSRLPDGSVAELTVGHYRTPSGRTVDDAGITPDLVVGDHAERRARTVL
                     SGLGAGA"
     gene            6546..7043
                     /gene="smpB"
                     /locus_tag="SL103_RS04505"
                     /old_locus_tag="SL103_04505"
     CDS             6546..7043
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene="smpB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016826026.1"
                     /locus_tag="SL103_RS04505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_04505"
                     /product="SsrA-binding protein SmpB"
                     /protein_id="WP_069567479.1"
                     /transl_table=11
                     /translation="MAKDKGKDKTPGRKLVAQHKKARHDYLILDTYECGLVLTGTEVKS
                     LRQGRASLVDGFVQIDGNEAWLHNVHIPEYAQGTWTNHAARRKRKLLLHRHEIDKLESK
                     SHESGHTIVPLALYFKDGRAKVEIALAKGKKEYDKRQTLREQQDRREADRAVSAARRRQ
                     RA"
     tmRNA           7149..7519
                     /db_xref="RFAM:RF00023"
                     /gene="ssrA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="SL103_RS04510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="SL103_04510"
                     /product="transfer-messenger RNA"
     gene            7149..7519
                     /gene="ssrA"
                     /locus_tag="SL103_RS04510"
                     /old_locus_tag="SL103_04510"
     gene            complement(7598..8872)
                     /locus_tag="SL103_RS04515"
                     /old_locus_tag="SL103_04515"
     CDS             complement(7598..8872)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512324.1"
                     /locus_tag="SL103_RS04515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_04515"
                     /product="MFS transporter"
                     /protein_id="WP_069567480.1"
                     /transl_table=11
                     /translation="MILFLAARPVTAPPVRPAPRRRPRFRPLAPYRRILAVPGARAFTA
                     ANLLARLPMGMFSVSAVLMIAGSRGSYALAGAVTATGLAATALAGPWTARMVDRHGQSR
                     VAVPATAFAVLGSLSLLLCVHLRAPDWTLFASYAATATTPNTGGMSRARWAHLFRDDPA
                     ARHTANSFEQAADELCFMLGPVLATLLCTTLFPEAGTAVAATLLLTGVLLFAARRDTEP
                     PVAARPAGTHGQRAATPLRLPGLPPLLLTFLATGAIFGSLEVVTLAYADDHGIRSAAGG
                     MLALQAAGSGAAGLLYGLLRPAGRLGDRFLTCVGAMAGLMLLPLAAAATGSAPALAAAL
                     LAAGMATAPTMVTGMGLVQARTPADRLNEGMTLAVTALLGGIAAGAAAGGFAVDHLAAP
                     AAAYGVPATAAALALTLARSGRRAW"
     gene            9007..10014
                     /locus_tag="SL103_RS04520"
                     /old_locus_tag="SL103_04520"
     CDS             9007..10014
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018564086.1"
                     /locus_tag="SL103_RS04520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_04520"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_069567481.1"
                     /transl_table=11
                     /translation="MPSDIDPRLLRAFTAVAEELHFTRAAARLYVAQQALSRDIRRLER
                     EVGAALFVRTTRQVSLTADGARLLPYARRVLTAHEELAAAFRPAPERPLLVDVGVPVGT
                     AYRVLEEARGRLPDSCELVARFHSGLTGAAGELLAGRLDVSFGRYAGLPAAVRAGLEHQ
                     PVRLEPMAVLLREDHPLAARPEVPLAELAGETLYAAAGNPQTVEWTELAARLFAGRGIA
                     MAEPFPEIDGSQEFVRVVRKRGWSVLASVEFIEVPGMVLRPVVEPVPLSPVSMVWRRGL
                     GHPGLAALRAVAGQLGRRDGWLTVPEGGWLPPEDARAMGVAGPVPSGGAETTER"
     gene            complement(10001..10459)
                     /locus_tag="SL103_RS04525"
                     /old_locus_tag="SL103_04525"
     CDS             complement(10001..10459)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986508.1"
                     /locus_tag="SL103_RS04525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_04525"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_244303837.1"
                     /sec_met_domain="PF13471 (E-value: 1.4e-25, bitscore: 88.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVPAVPPPRRPPVDPMTGPAPLPAGGRLTVRERCGARAAVAVA
                     RVLAALPPHRMCRLLERIRRGARPATAAEALRARHAVVTVSPHCAGDGCLPRSLATALL
                     CRARGHWPQWCSGVRTAPFRTHAWVAVDGRPVGEPAETAFYHRVLSVP"
     gene            complement(10456..12603)
                     /locus_tag="SL103_RS38555"
                     /old_locus_tag="SL103_04530"
     CDS             complement(10456..12603)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542336.1"
                     /locus_tag="SL103_RS38555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_04530"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_069567482.1"
                     /sec_met_domain="Asn_synthase (E-value: 3.2e-18, bitscore:
                     65.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFLVLPDHPASDALGRCLPASPARRTLRHPSGRPWITGHWSADE
                     AVPAEAGPRRALLLGTTPATPGTLARLLPGPGHLDGIGRRARRLPGSAFLLTAADGDLR
                     CRGDLAGVRLLHHARIAGVTVAGNRPQDLAALARAAAAAGLPAGAPGLGFLDEDAPALR
                     LLFPFAPLPLALRPAWHAVSAVPPGHHLTLYANGRHSLARWWRPPEPDIPLEHAAEHVA
                     GALADAVAARAGRAQRQAAADGTARRGTLSAGLSGSTGATGLCFLAAREDVRLLTTSWA
                     SRDPGDEDTRWSARGAATLAAAERQRERQRRRLTGQDTGQERDGNGGRRRNKGTGKDAA
                     RGRRGGRGAAGAPPPPEAHLSLPYADAPTCYTPPTDTRHGTPADPAGPLAVFREAARLA
                     HRARLVAEHGSRLHLVAAGADALFGHRPAALNSLAHGDLRTAARRAWTAHHLCHWTARD
                     TLRTLRGGRSYARWLAGSAPRAPGPGRRAGGADWEPPPALPPWAHPDAVATVRRLLREA
                     ADEAPEPFAPLRAQHDILRAALHAAETVRGADALTAAHGVGHEAPFLDDAVVEAALALD
                     LADRGRPGVHQPLLTRALRGVVPDGVLGRGTHTGPGPEAHAGLRAHRDALAALCDDSPL
                     AARGLIHPDVLRRHLTAPQPQPPVLRALDATLATEYWLRAVAPDHAPAPAVSVPAVPAP
                     AVSVPAVPVPRAAPARGVPSP"
     gene            12932..14374
                     /locus_tag="SL103_RS04535"
                     /old_locus_tag="SL103_04535"
     CDS             12932..14374
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091252.1"
                     /locus_tag="SL103_RS04535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_04535"
                     /product="nitrate/nitrite transporter"
                     /protein_id="WP_079145564.1"
                     /transl_table=11
                     /translation="MTAEAAAGTRSDSPGASRTEGRARRGGRWIERWEPEDEGFWRETG
                     ERIARRNLAFSVLSEHIGFSVWSLWSVMVLFMGPEYGIDPAGKFFLVAIPTLVGGVLRV
                     PYTFAVALFGGRNWTVISALLLLVPTAAAAVVMHPGTSYTTFILVAMVAGVGGGNFASS
                     MTNINSFFPLRKKGFALGLNAGGGNIGVPVIQLLGLLVIGTAGAGHPRLVLAVYVPLIV
                     LAAVLAALFMDNLAPVTHDTGAALDAARQPHTWVMSLLYIGTFGSFIGYSFAFGLVLQN
                     QFARTPLQAASLTFVGPLLGSLLRPVGGRLADRFGGARITLGTFAAMGLATGVVIRASA
                     DHSLPVFLVGFFALFVLSGLGNGSTYKMIPGIFQAQALRRGLAGEAAAAYGRRLSGAAM
                     GLIGAVGALGGLAINLAFRQAFLTAGSGTPAFVSFLVCYAVCAAVTWAVYLRPAARERR
                     AARAGAAGAAAEGERRAVHAEV"
     gene            14525..15748
                     /locus_tag="SL103_RS04540"
                     /old_locus_tag="SL103_04540"
     CDS             14525..15748
                     /EC_number="4.2.1.75"
                     /GO_function="GO:0004852 - uroporphyrinogen-III synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006780 - uroporphyrinogen III biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091253.1"
                     /locus_tag="SL103_RS04540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_04540"
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="WP_069567483.1"
                     /transl_table=11
                     /translation="MDEQHQGRGERERTEPGTAPGVRPLDGFTIGVTAARRAEELGALL
                     ERRGGQVLHAPALRIVPLPDDTELLAVTRALIDDAPDVVVATTAIGFRGWVEAAEGWGL
                     GEALLDRLAGVELLARGPKVRGAIRAAGLTEKWSPASESMAEVLDRLLEEGVAGRRIAL
                     QLHGEPLPGFVEALRAGGAEVVGVPVYRWMPPEDLGPVDRLLDATLAGGLDAVTFTSAP
                     AAASLLRRAAERGIRDALLAALRTDVLPVCVGPVTALPLEAEDVPTLQPERFRLGPLVQ
                     LLCRELPGRVRPLPVAGRRLEIRGHAVVVDGVLRPVPPAGMALLRALARRPGWVVARAE
                     LLRALPGAGRDEHAVETAMARLRVALGAPKLIQTVVKRGYRLALDPHADTDKYSGEDTQ
                     VRRVAPGC"
     gene            complement(15723..16508)
                     /locus_tag="SL103_RS04545"
                     /old_locus_tag="SL103_04545"
     CDS             complement(15723..16508)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542333.1"
                     /locus_tag="SL103_RS04545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_04545"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_069567484.1"
                     /transl_table=11
                     /translation="MSRKSLLTNRASLTHKIGYAVRNPARITPYVKRTARDTWLRLKHP
                     DHVAYYRAVMASDTGRSPEAAVGSRSHERWLALGEMQFAYLAGHGLRPEHRMLDIGCGN
                     LRAGWRFIAHLDTGNYYGIDISPDILIAAKRTLTTYELQDKLPHLTITQDLKLDFLPAG
                     HFDVVHAHSVFSHSPLDVIDECLAHVGRILAPGGFFDFTFDRTEGTEHQVLREDFYYRT
                     DTLLRLARGHGLEARFMDDWETRPHGQSKIRVSNPARPS"
     gene            16790..17533
                     /locus_tag="SL103_RS04550"
                     /old_locus_tag="SL103_04550"
     CDS             16790..17533
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091255.1"
                     /locus_tag="SL103_RS04550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_04550"
                     /product="ABATE domain-containing protein"
                     /protein_id="WP_079145565.1"
                     /transl_table=11
                     /translation="MAAACDLRFDCGRTCLDLVATAGDAPAERLTGPEQLAAWLVGAGL
                     VPRGVPLDAVDGRWVVRFRALRDLVCRVVHDELRDRAADADLDRLNSAAAAGPPPAPRA
                     VRGADGTLARTLCAPPDCAGLLAAVARDAVGLLTDPVARGQLRQCAGEHCSLVYLDGSR
                     GRRRRWCSSEVCGNRERVARHRRRSTVRGATGPAGGPVPSGAAPGPARVPSPEPVGPPP
                     EPVGPPPEPLAPASVMPGKNFPAGG"
     gene            17608..18174
                     /locus_tag="SL103_RS04555"
                     /old_locus_tag="SL103_04555"
     CDS             17608..18174
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004571957.1"
                     /locus_tag="SL103_RS04555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_04555"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_069567485.1"
                     /transl_table=11
                     /translation="MRAIDPGVGVRKDAVVADRTTPDEELMRALYDEHAGPLLAFVLRL
                     VAGDRHRAEDVVQETLVRAWRNADQLQRATGSIRPWLVTVARRIVIDGHRSRKARPQEV
                     DATPLETMPAADVIDRALRMMTISEALSDLSQAHREALVETYFKERTVNEAAEVLRVPA
                     GTVRSRVFYALRSLKLSLQERGVTE"
     gene            18171..18917
                     /locus_tag="SL103_RS04560"
                     /old_locus_tag="SL103_04560"
     CDS             18171..18917
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605308.1"
                     /locus_tag="SL103_RS04560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_04560"
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="WP_069567486.1"
                     /transl_table=11
                     /translation="MIPPTQPDRHTDVGAYALGVLDAADAERFEAHLVGCDRCAAELEE
                     LMGLTPALAEFKESAPTPETLTAVPGPRLLNGLLDEVAATRRGRARRRLFLVAAAVVLI
                     VGGPLAALSLKGDADAPPAAAPPLANAVRAQYAEGEKAGSVDPVTKVSAGVSMAPRPWG
                     TQVVLELANVKGPLSCDLVAVGKDGRRQTVTTWAVPKGGYGIPGSAAKWNREPLYAAGG
                     AALDRADIDHFEISTLEGRRLATVKV"
     gene            19059..21542
                     /locus_tag="SL103_RS04565"
                     /old_locus_tag="SL103_04565"
     CDS             19059..21542
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605310.1"
                     /locus_tag="SL103_RS04565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SL103_04565"
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="WP_069567487.1"
                     /transl_table=11
                     /translation="MAAHNATHAPDHAPDSVRDREIEAEQTHLDRVYRRLEEKIHEAEF
                     LMDDAAKRGQVGTPGALAERDAQVFQAGVHLHRLNSEYEDFLFGRIDLLLGKDGKKGPD
                     GAYTSVEPADGAVENNRATIAETLHIGRLGVLDADYSPLVIDWRAPAAAPFYRATPVAP
                     GRVVRRRVIRSKGRRVLGVEDDLMRPEVTATLDGRELPAIGDGALMAALGRARSHTMRD
                     IVASIQAEQDMVIRAPAASVTEVEGGPGTGKTAVALHRAAYLLYQDRRRYAGGILIVSP
                     TPLLVAYTEGVLPSLGEEGQVAIRALGSLVDGAEATAYDPPAVARIKGSSRMQKLLRKA
                     ARGALELAAPPAGGVAEDAGPDTQLSLEDLVRGPDGPAPRGGARRRTRGGSARPASTAP
                     ARLRVVAFGTRLELDADELHAIRQSALGGTAPVNLLRPRARRLILDALWAKSGAGRRYT
                     DPELAAEAREGFDEDLTTEPVLQEFLDAWWPELTPRGVLAAMADERLLSRWARRVLNPR
                     EVRQLARSLGRLDAAGQGPLSVHDIALLDELQQIVGAPMRPARPREADPLDHLTGLEEL
                     TTWADRNGGGRGRRERLEEERTDYAHVIVDEAQDLTPMQWRMVGRRGRQATWTVVGDPA
                     QSSWSDPDEAALARDEALGTRPRRRFTLTVNYRNPAEIAELAGKVLALAMPGMQSPKAV
                     RSTGLRPRFALAGDGAGPTGDKELERATVAAAGRLLDEVDGTVGVVVAMNRREQARRWL
                     APLGDRVVALGSLEAKGLEYDATLVVSPAEIADESPAGLRVLYVALTRATQQLTVLSTA
                     RDEPDAAAVPDLLRD"
     misc_feature    21641..21650
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.14"
                     /tool="antismash"
     misc_feature    21820..21834
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.32"
                     /tool="antismash"
     misc_feature    complement(21822..21833)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.9"
                     /tool="antismash"
     misc_feature    21827..21841
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.95"
                     /tool="antismash"
     misc_feature    complement(21851..21866)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.19"
                     /tool="antismash"
     misc_feature    22206..22219
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.41"
                     /tool="antismash"
     misc_feature    22287..22302
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.24"
                     /tool="antismash"
ORIGIN
        1 gccgcgcgcc tcggtggacg tctacgcgct ggcgaccgtc ctgtacgaga tgctcgccgg
       61 gttcacgccc ttcgggggcg gccaccccgg cgcggtgctg cgccgccacg tcaccgagag
      121 cgtcgcgccg ctgcccggca tccccgacga gctgtggcag ctgctggtgc agtgcctggc
      181 caaggcgccc gcgtcccggt tgcgcgcccc ggaactcgcc gcccggctgc gggagctgct
      241 gccgggcctg gccgggatgc cgccgctgga catcgacgag ccggacggcg agcagccgga
      301 ggacgaggcg gacggcgctg ccggggcccg cgaggaggcg ttctacccgt cctccggggc
      361 gggcgaggcc acgccgccgc gcggcgcggt ccccctggtg cagggctcgg ccccggactc
      421 caaccgggag acgcacacca gcatgcgggt gccgggcccg gacgagctgg cgggcggcgc
      481 gcacggcacg gcgcgggccc cgcgggcggc cggtgagcgc cgggcgggct cggcgcggca
      541 ccgggcgtcg ccggaggcgc tgcgccggcg ccggatcagg ctgggcgccg cggccgccgc
      601 ggtggtggtg gccgcgggcc tgggcggctg gctggcgtcc gacgacgacg gttccggcga
      661 cgccacgccg ggggtccacc agcaggggcc ggacgctccg tgacggcccg gtgacccgga
      721 ccgggcgggt tgacctgccg gggccgggtc acgctgccgg tggttgccgt taggctgggt
      781 gcgtggcagt cgtcgatgta tccgaagagc tgaagtccct ctcctcgacc atggggtcga
      841 tcgaggccgt cctggacctc gacaagatga gggccgacat cgccgtgctt gaggagcaag
      901 cggcggcgcc gtccctgtgg gacgacccgg agagcgccca gaaggtcacc agccagctgt
      961 cctacctcca gggccagctg cgccgggccg aggaactgcg cggccgggtc gacgacctgg
     1021 aagtcctctt cgagctcgcc gacgccgagg gcgacgagga cgcccgggcc gaggccgaga
     1081 ccgagctgac cgacgtccgc aaggccgtcg aggagctgga ggtccgcacc ctcctgtccg
     1141 gcgagtacga ctcccgtgag gccctcgtca acatccgtgc cgaggccggc ggggtggacg
     1201 ccgccgactt cgccgagaag ctgcagcgca tgtatctgcg ctgggccgag cggcacggct
     1261 acaagaccga gctctacgag acctcgtacg cggaagaggc cggcatcaag tcgaccacct
     1321 tcgcggtcaa cgttccctac gcctacggca ccctctccgt cgagcagggc acgcaccgcc
     1381 tggtgcgcat ctcgccgttc gacaaccagg gccgccgcca gacgtcgttc gccggcgtcg
     1441 aggtgctgcc cgtcgtcgag cagaccgacc acatcgagat cgacgagtcg gacctgcggg
     1501 tggacgtgta ccggtcgtcc gggcccggcg gccagggcgt caacaccacc gactccgcgg
     1561 tgcggctgac gcacatcccc accggcatcg tcgtgtcctg ccagaacgag cgctcgcaga
     1621 tccagaacaa ggcgaccgcg atgaacgtcc tgcaggccaa gctcctggag cggcgccgcc
     1681 aggaggagca ggccaagatg gacgcgctca agggcgacgg cggcaactcc tggggcaacc
     1741 agatgcgctc gtacgtcctg cacccgtacc agatggtcaa ggacctgcgc accgagttcg
     1801 aggtcggcaa cccgcaggcc gtgttggacg gtgacatcga cggcttcctg gaggccggga
     1861 tccgctggcg caagcagcag gagaagtaac cgcgccgccc tcggcgagcg ctccctgaca
     1921 ccggaacaac tgcctccctc ggggaggcag ttgtttttgt cgtggtggtt tggtcacagt
     1981 cgtatgtcca tgtaccgcgc aaccgacgcg aattcgggca tccggccttt aatcggcctt
     2041 gacgatgttc gtcttcctgg gaaggctgag cgcggcatgc gtatgtctgg ggcgcgtgta
     2101 ggaacgggga gatgagtggc ctgtcggcaa tccggggcca cgacacgcgt cccctcggcc
     2161 cgtcgccccg tacagcggtg ctccaatgac gagttcagct actgggggta gcagtacatg
     2221 acgaagaaga cgcggctgcg cgtagcgcgc attgcggccg gtgcggtgat cgcggcgggt
     2281 gcgtcgctca ccgcggccgg cgtggcctcc gcggctcccg ccgacggtac gggcggtgag
     2341 agcggcggca tcatcggcgg cctcctcggc ggtgtcctcg gcggcggtga ctccggcggt
     2401 gactcctcgg gtggtgacac caccggcggc gacaccaccg gcggtgacac ggccggccag
     2461 gtcggcggcg gcgagatcgg cggcgactcg ggcggcgaga tcggtggcga ccagaccggt
     2521 ggcgagacca ccggcggtga caccaccacg ggtggcgaga ccaccggcgg ccagaccacg
     2581 ggtggcgaga ccaccggtgg cgacaccacc acgggtggcc agaccaccgg tggccagacc
     2641 accggtggcc agaccacggg tggcgagacc accggtggcc acaacagcgg tggccagtcc
     2701 accggcggcg acagcaccgg tggccacaac agcggtggcc agtccaccgg tggcggcaac
     2761 ggcggcaacg gtggcaacgg cggccccagc ggtggcacca ccaccggcgg cgactccacc
     2821 ggcaccggca ccgacaacga gggctccaag ccggtcgagc agcccggcca gggcaaggag
     2881 cagatcgctg acacgcccgg ccaggccaag cagcaggcga agggcgggga gctggccgag
     2941 accggttcct ccggcaccac cttcctgctc atcggtgcgg ccacgatgat cgcgggcggt
     3001 gtgggcttcc gtgtgctgcc ccgcctgatc aacaagaacg gcggcggcgc ggcagcggcc
     3061 tgacgctgac gcggcaccac gaggggcccg ggacgcacac agcgtcccgg gcccctcggc
     3121 gttcacactc ccgccacggg cgggacagcg tcatatgcac ccggtagggg tgcggcgtgc
     3181 gtcagacggc ctggtggagc agcaccccga ccgcgatgag cacgatcatc agtgccacca
     3241 gcatcacggg gctgagctgg gcgaacacgc cgcccgcttg ctgctggagc cgttccctgc
     3301 tcgcccggca cacagggcag cggccctcgc tcacaggggc cgcgcagttg gcgcacacca
     3361 gtcggtcgta cgtcatgcga cctccttctt cactgcacca acgcaccggg gtgcacattg
     3421 gttccccctt ccactgtgcc agctccccgc cggaacggcg cgccccgcag gattgtgcgg
     3481 ctttttgtcc caaaggtgcc gtgaagaaac gcaccatccc cctacgccga ctgcaccgcc
     3541 ccgcgaggtt cgcgtatggt cacgcacacc gacgggagcc gcaactcggc aacccgtgcc
     3601 gctatccagg tcgaccgtgg tgcatcagtg atccgattcg acaacgtctc caagacctac
     3661 ccgaagcaga accgccctgc actcagggac gtctcgctcg agatcgagcg cggcgagttc
     3721 gtcttcctgg tgggctcctc cggttccggc aagtccacct tcctgcggct gctgctgcgc
     3781 gaggagcggg ccagccacgg ccatgtgcac gtactcggca aggacctcgg gaagctctcc
     3841 aactggaagg tcccgcagat gcggcgccag gtggggacgg tcttccagga cttccggctg
     3901 cttcccaaca agaccgtcgg ggagaacgtc gccttcgccc tcgaagtcat cggcaagccg
     3961 cggggccaga tccgcaagac ggtccccgag gtcctcgacc tcgtcgggct cggcggcaag
     4021 gaggaccgga tgccgggcga gctgtccggt ggtgagcagc agcgcgttgc catcgcccgg
     4081 gccttcgtca accgcccgat gctgctcatc gccgacgaac ccaccggcaa cctcgacccg
     4141 cagacctcgg tcggcatcat gaagctgctg gaccggatca accggaccgg tacgacggtg
     4201 gtcatggcca cccacgacca gcagatcgtc gaccagatgc gcaagcgggt catggaactc
     4261 gagaagggcc ggctcgtacg cgaccagtcg cgcggcgtgt acggctacca gcactgaaag
     4321 gacgccatgc gcgcccagtt cgtcctgtcg gagatcggcg tcggtctccg ccgaaacctc
     4381 acgatgacct tcgcggtcat cgtctccgta gccctctcgc tgggcctgtt cggcgcctcg
     4441 ctgctgatgc gcgaccaggt cagcacgatg aagggctact ggtacgacaa ggtcaacgtc
     4501 tccatcttct tctgcaacaa gaacgacgcc gaaaccggcg ccaactgcgc caagggcgcg
     4561 gccacccagc agcagaagaa cgacatcaag gcggagctgg accggctgcc gatcgtccag
     4621 agcgtgaccc acgagtccag cgaccaggcg tacaagcact acaaggagca gttcggcgac
     4681 acgcccgtgg ccggactggt gacgcccgac cagcttccgg agtccttccg cgtcaagctc
     4741 aaggacccca ccaagttcac ggtcatcaag tcggcgttct ccgagcggcc cggtgtgcag
     4801 gaggtgcagg accaacggga caccgttgag ccgctgttca acctcctcaa cggcatgaac
     4861 atcgccgcgc tgtgcgtgat ggggttgatg ctcgtcgttg cgctgatgct gatcgtcaac
     4921 accgtgcggg tgtcggcgtt cagccgtcgg cgggagaccg gcatcatgcg gctggtggga
     4981 gcgtccagct tctacatcca gatgccgttc atcctggagg ccgccatcgc gggcctgctg
     5041 ggcgccgcgt tcgcctgcgt gctgatcgtc ggcggcaagt acgtcctcgt caacaactgg
     5101 ctggcgaaga agatccaggt gatcaacttc atcggctggg actcggtggc ggcggtgctt
     5161 ccgctggtgc tgctgatcgg gctgctgatg cccgcgctcg ccgcgttctt cgcgctgcgc
     5221 aagtacctca aggtgtgagc tttgccaagg ggcgccgtac ggacaacttc ccgtacggcg
     5281 cctttttgtc ccctagactc accggcatgt cgggcccgtg ttcgtacgtc cggccccgcc
     5341 gcattcgccg cggggcggcc ctgacgttgt tcctcgcgag tgtgctggcc accggtgcgg
     5401 tgaccggcac atggagcgac gaggcggcgg gcgcgggcgg ccgcgccgcc ccggaccacg
     5461 ccgttccgcg ggcccacggc tccgcgtccg cgcggtcctc cgccaccgcc gaccgcgcgg
     5521 ccgtggagcg ggccgccacc gaagccgtcg aggacggcaa gtccggttcc caggcggccg
     5581 ccgacgtggt cagccgcagc ggcgaccgct ggtcgtcgat ctacacaccg ggcgagttcg
     5641 aggatttcca ggcgcagttg gacggccgtt acgtcggtgt cgggctgtgg gtgcggcagg
     5701 tgggggaccg gaccgaggtg tcccgggtcc ggccgggcag ccccgcggcg ggggccggcg
     5761 tcgccgtcgg tgacctgctg cgggccgtcg acggccgcgc cacgcggggc cgtccggtca
     5821 ccgagaccgt cgcggcgctg cgcggcgata cccggcgcgg ctcccggacc gcggtcggca
     5881 cggccgtacg gctcgacctg cagcggggtg accgccgctg gagcgtgacc ctgcaccgcg
     5941 tccggctgcg cacccgcaac gtcgtcaccg accggccggc cgggccgcac ggtccgaccc
     6001 gcgtcaagat cgcctcgttc gcgaggggga ccggcgacgc ggtccgccgc gcggtgcgcc
     6061 gggcctcgcc gcacggcggt ctgctgctcg acctgcgggg caacacgggc gggctggtca
     6121 ccgaggccgt cgccaccgcc tccgccttcc tggacggcgg cctggtcgcc acctacgaca
     6181 tgcggggtgc ccagcgtgcg ctgtacgccg cgcgcggcgg caacacccgg ctgccgctgg
     6241 tggtgctcgt cgacggcggc acgatgagcg ccgccgaact gctgaccggg gcgctccagg
     6301 accgcggccg ggcggtcgtg gtgggctccc cgaccttcgg caagggctcg gtgcagatgc
     6361 ccagccggct gccggacggc tcggtcgccg agctgaccgt cggccactac cgcaccccgt
     6421 cggggcggac cgtcgacgac gccggcatca cccctgacct ggtcgtcggg gatcatgccg
     6481 agcggcgggc ccgcacagta ttgagtggcc tcggagcggg tgcgtagtgc gaaaatggcc
     6541 gcactatggc taaggacaag ggcaaggaca agactcccgg gcgcaagctc gtcgcacagc
     6601 acaagaaggc gcggcacgac tacctcatcc tggacaccta cgagtgcggt ctggtgctga
     6661 ccggtaccga ggtgaagtcg ctgcgtcagg gccgggcgtc gctcgtggac ggcttcgtgc
     6721 agatcgacgg caacgaggcg tggctgcaca acgtgcacat tcccgagtac gcccagggca
     6781 cctggaccaa ccatgcggcg cggcggaagc ggaagctgct gctgcaccgc cacgagatcg
     6841 acaagctgga gtccaagagc cacgagtcgg ggcacacgat cgtgccgctg gcgctctact
     6901 tcaaggacgg ccgggccaag gtcgagatcg cgctggccaa gggcaagaag gagtacgaca
     6961 agcggcagac gctccgtgag cagcaggacc gccgcgaggc ggaccgggcg gtgtccgcgg
     7021 cccgtcggcg gcagcgggcc tgacctgcgg gtgcggggcc cgggaatacg ctggaaacct
     7081 cacccgttgt tcacgtacga tggctgcgca ccccacggag ggtgtgcacc acattgaaaa
     7141 atcaacatgg ggatgatcgg tttcgacagc ggatgtcgaa gcaggggaag cgtgtcgagg
     7201 aagcggcaat gatctcgtaa accatatgcc gaaaccaata atcgccaaca ccaagcgcga
     7261 ttccttcgcc ctcgctgcct aagtagcgac ctgcgaagtg tcagcccggg gatgatcccg
     7321 acccggatcc tggcatcagc taggggtctt atccgttgag cccggtcacg gggcgcaacg
     7381 gagacatcaa acagtgactg agcccgtcgg agacttgttc gcgtgatctc cggggctgag
     7441 aaaatcgcag cgaactgcac acggagaagc cctgattcca caccgttgga cgcgggttcg
     7501 attcccgcca tctccactca tcccatgtag cgcagcgccc ccgcgagatt ctcgcggggg
     7561 cgctgcgttg ttgtgtcctc gcccgcgccc ggccggctca ccaggcccga cggcccgacc
     7621 gggcgagggt gagggcgagg gcggccgccg tggcggggac cccgtaggcg gccgccgggg
     7681 cggccaggtg gtccaccgcg aagccgcccg ccgccgcgcc ggccgcgatc ccgcccagca
     7741 gggccgtcac cgccagtgtc atcccttcgt tcagccggtc cgccggggtg cgggcctgga
     7801 ccagtcccat gccggtgacc atggtcggtg cggtggccat gccggccgcg agcagcgcgg
     7861 cggccagcgc cggcgcgctc ccggtggccg cggccgcgag cggcagcagc atcagcccgg
     7921 ccatcgcgcc gacgcaggtc aggaagcggt ccccgaggcg gcccgccggg cgcagcaggc
     7981 cgtacagcag cccggcggcg ccggacccgg ccgcctggag ggccagcatg ccgcccgcgg
     8041 cggagcggat gccgtggtcg tcggcgtagg cgagggtgac gacctccagg gagccgaaga
     8101 tcgcgccggt ggcgaggaag gtgagcagca gcggcgggag gccgggcagc cgcagcggtg
     8161 tcgccgcccg ctgcccgtgg gtgccggccg gccgggccgc caccggtggt tcggtgtcgc
     8221 gccgggcggc gaagagcagt acgccggtca gcagcagcgt cgcggccacc gcggtccccg
     8281 cctcggggaa gagggtggtg cacagcagcg tcgcgagcac cgggccgagc atgaagcaca
     8341 gttcgtccgc ggcctgttcg aaggagttgg cggtgtgccg ggcggccggg tcgtcgcgga
     8401 agaggtgcgc ccagcgggcg cgggacatcc cgccggtgtt gggtgtggtg gcggtggcgg
     8461 cgtacgacgc gaacagggtc cagtcgggcg cccggaggtg gacgcacagc agcagcgaga
     8521 gcgagccgag gacggcgaac gcggtggccg ggaccgcgac gcgggactgg ccgtggcggt
     8581 cgaccatgcg ggcggtccac ggcccggcca gcgccgtcgc cgcgaggccg gtcgcggtga
     8641 ccgcaccggc cagcgcgtag gagccgcgcg agccggcgat catcagcacc gcgctgacgc
     8701 tgaacatccc catgggcagc cgggccagca ggttggcggc ggtgaaggcg cgggcgccgg
     8761 ggacggcgag gatccggcgg tagggggcga gcgggcggaa gcgggggcgg cggcgcgggg
     8821 cggggcgtac ggggggcgcg gtgacggggc gggcggcgag gaagaggatc atgcctcata
     8881 cggtggcggc agccgccggt gtcggtccaa cacctgatga gcaccgattc acgcggctgt
     8941 gttgtcaatg gggcgggggg cggcagcggg gtcggcgggg gcggccggca ctgccaggat
     9001 ggcccggtgc cgtccgacat cgatccgcgt ctgctccggg ccttcaccgc cgtcgccgag
     9061 gagctgcact tcacccgcgc cgcggcccgg ctgtacgtgg cccagcaggc gctgagccgc
     9121 gacatccggc ggctggaacg ggaggtgggc gccgcgctgt tcgtgcggac cacccgccag
     9181 gtctcgctga ccgccgacgg ggcgcggctg ctgccgtacg cgcggcgggt gctgaccgcg
     9241 cacgaggagc tggccgcggc cttccggccg gcccccgagc ggccgctgct ggtcgacgtc
     9301 ggggtgccgg tcggcaccgc ctaccgggtg ctggaggagg ccaggggccg gctgccggac
     9361 agctgtgagc tggtggcccg tttccacagc ggactgaccg gcgcggcggg ggagttgctg
     9421 gccgggcggc tggacgtctc cttcgggcgg tacgcggggc tgccggcggc cgtgcgggcc
     9481 ggtctggagc accagccggt ccggctggag ccgatggcgg tgctgctgcg ggaggaccat
     9541 ccgctggcgg cgcggccgga ggtcccgctc gcggaactgg ccggcgagac gctgtacgcg
     9601 gccgccggga atccgcagac ggtggagtgg acggagctgg cggcgcggct cttcgcgggg
     9661 cgcggcatcg cgatggccga gccgttcccg gagatcgacg gctcgcagga gttcgtacgg
     9721 gtggtgcgta aacggggctg gtcggtgctg gcgagcgtgg agttcatcga ggtgccgggg
     9781 atggtgctgc gcccggtggt ggagccggtg ccgctgtcgc cggtgtcgat ggtgtggcgg
     9841 cgggggctgg ggcaccccgg gctggcggcg ctgcgcgcgg tggcgggcca actggggcgc
     9901 cgggacggct ggttgacggt cccggagggc ggctggctgc cgccggagga cgcgcgtgcg
     9961 atgggcgtgg ccgggccggt gccgagcggg ggcgcggaga ctacggaacg ctgagcacgc
    10021 ggtggtagaa ggccgtctcg gcgggttcac cgacggggcg gccgtcgacc gcgacccagg
    10081 cgtgggtgcg gaacggcgcg gtgcgtacgc cgctgcacca ctgcggccag tggccgcggg
    10141 cgcggcacag cagcgcggtg gccagggagc gggggaggca gccgtcgccc gcgcagtgcg
    10201 ggctgaccgt gaccacggcg tgccgggccc gcagcgcctc cgccgcggtg gcgggccggg
    10261 cgccgcgccg gatccgctcc aggaggcggc acatccggtg cggcggcagc gctgccagga
    10321 cccgggcgac ggccaccgcc gcgcgggcgc cgcagcgttc gcggacggtg agccggccgc
    10381 cggcggggag cggggcgggg ccggtcatcg ggtcgacggg cgggcggcgg ggcggcggga
    10441 cggcgggtac ggcggtcatg gggacggcac tcctctcgcc ggggcggcgc gggggacggg
    10501 gacggcgggt acggacacgg ccggcgcggg gacggcgggt accgacacgg ccggcgcggg
    10561 ggcgtggtcg ggggcgacgg cgcgcagcca gtactcggtg gcgagggtgg cgtccagggc
    10621 ccgcaggacg ggcggctgcg gctgcggggc ggtgaggtgg cgccgcagga cgtcggggtg
    10681 gatcaggccg cgggcggcga gcggggagtc gtcgcagagg gcggccaggg cgtcgcggtg
    10741 ggcgcgcagg ccggcgtggg cttcggggcc gggcccggtg tgcgtaccgc ggccgaggac
    10801 gccgtcgggg acgacgccgc gcagcgcgcg ggtgagcagc ggctggtgga cgccgggccg
    10861 gccgcggtcg gcgaggtcga gggcgagcgc cgcctcgacg accgcgtcgt cgaggaacgg
    10921 cgcctcgtgg ccgacgccgt gcgcggcggt cagggcgtcg gcgccgcgga cggtctccgc
    10981 ggcgtgcagg gcggcacgga ggatgtcgtg ctgggcgcgc agcggcgcga acggttcggg
    11041 ggcctcgtcg gcggcctcgc gcagcagccg gcggacggtg gcgacggcgt ccgggtgcgc
    11101 ccacggcggc agggcgggcg gcggctccca gtcggcgccg ccggcccgcc gtcccgggcc
    11161 gggcgcccgg ggtgcgctgc cggccagcca ccgggcgtag gagcggccgc cgcggagcgt
    11221 gcgcagggtg tcgcgggcgg tccagtggca gaggtggtgg gcggtccagg cgcgccgggc
    11281 ggcggtgcgc aggtcgccgt gggcaaggga gttgagggcc gccgggcggt gcccgaacag
    11341 cgcgtcggcg ccggcggcga cgaggtgcag ccgggagccg tgctcggcga ccagccgggc
    11401 ccggtgggcg aggcgggccg cctcgcggaa gacggcgagc gggcccgccg ggtcggcggg
    11461 ggtgccgtgg cgggtgtcgg tgggcggggt gtagcaggtg ggggcgtcgg cgtacggcag
    11521 ggagaggtgc gcctcgggcg ggggcggggc tcccgcggcg ccacggccgc cgcgccgccc
    11581 ccgggcggcg tccttgcccg tgcccttgtt cctgcgcctg ccgccgttcc cgtcccgctc
    11641 ctggccggtg tcctgcccgg tgagccgccg gcgctgccgt tcgcgctgcc gttccgccgc
    11701 ggcgagggtg gcggcgccgc gggcgctcca ccgggtgtcc tcgtcgccgg ggtcgcggga
    11761 cgcccaggag gtggtgagca gccggacgtc ctcgcgggcg gcgaggaagc acagtccggt
    11821 ggcgccggtg gagccggaga ggccggcgct gagcgtgccg cggcgggcgg tcccgtcggc
    11881 ggcggcctgc cgctgtgcgc gcccggcacg ggccgccacc gcgtcggcca gcgccccggc
    11941 cacgtgctcc gcggcgtgct ccagggggat gtccggttcc ggtgggcgcc accaacgggc
    12001 cagggagtgg cgcccgttgg cgtacagggt gaggtggtgg cccgggggta cggcggacac
    12061 cgcgtgccag gcggggcgca gggccagcgg gagcggggcg aaggggaaca gcagacgcag
    12121 cgccggcgcg tcctcgtcga ggaagccgag gccgggggcg ccggccggga ggcccgccgc
    12181 ggccgcggcg cgggcgagcg cggccaggtc ctgggggcgg ttgccggcga cggtgacgcc
    12241 ggcgatccgg gcgtggtgga gcaggcggac gccggcgagg tcgccccggc agcgcaggtc
    12301 gccgtcggcg gcggtcagca ggaaggcgct gccggggagg cggcgggcgc ggcggccgat
    12361 gccgtcgagg tggccggggc cgggcagcag ccgggccagt gtgccggggg tcgccggggt
    12421 ggtgccgagc agcagcgcgc ggcgcggccc ggcctcggcg ggcacggcct cgtcggcgga
    12481 ccagtgcccg gtgatccagg ggcgtcccga ggggtggcgg agggtgcggc gggccgggct
    12541 cgccggcagg cagcggccga gcgcgtcgga ggcggggtgg tcggggagga cgaggaaatc
    12601 cacggtgggg gagcactcca ctggaggggc cggtgcggcg ccgggcgggc cgggtggacg
    12661 cggggcgcgc cacgggggtc acgcagcgcg ttcgacagga tgctgacagt gtccacgtca
    12721 atttccattg cctcgaagga gtgatcacgg gggcgtgcga ggcaaaccgg cgcgggccca
    12781 cagggcgcgc acgccggagc gtccgagatc gctcacgggg tccccgtgcg cctggtgagc
    12841 gcgaggtttc gcggcggtca cctcacgcca ccgcgccgaa acccgcggtc cctatgttcg
    12901 gggcagacga cccgactcct tgggaggcgc gatgacggcc gaggccgcgg caggcacccg
    12961 tagcgacagt cccggcgcaa gccgtaccga gggccgtgcg cggcgagggg ggcggtggat
    13021 cgagcggtgg gagccggagg acgaggggtt ctggcgggag accggtgagc ggatcgcccg
    13081 gcggaacctg gccttctccg tgctgtccga gcacatcggc ttctccgtct ggagcctgtg
    13141 gtcggtgatg gtgctgttca tggggccgga gtacgggatc gacccggccg ggaagttctt
    13201 cctggtggcg atcccgacgc tggtgggcgg ggtgctgcgg gtgccgtaca ccttcgcggt
    13261 ggcgctgttc ggggggcgca actggacggt gatcagcgcg ctgctgctgc tggtgccgac
    13321 cgcggcggcc gcggtggtga tgcacccggg gacgtcgtac accacgttca tcctggtcgc
    13381 gatggtggcc ggcgtcggcg gcgggaactt cgcctcctcg atgacgaaca tcaactcctt
    13441 cttcccgctg cgcaagaagg ggttcgccct ggggctgaac gcgggcggcg gcaacatcgg
    13501 ggtgccggtc atccagctgc tggggctgct ggtgatcggg acggcgggcg ccggccatcc
    13561 gcggctggtg ctggccgtgt acgtgccgct gatcgtgctg gcggcggtgc tcgcggcgct
    13621 gttcatggac aacctcgcgc cggtcaccca cgacaccggg gcggccctgg acgccgcccg
    13681 gcagccacac acctgggtga tgtcgctgct gtacatcggc accttcgggt cgttcatcgg
    13741 ctacagcttc gccttcgggc tggtactgca gaaccagttc gcccgcaccc cgctccaggc
    13801 cgcgtcgctg accttcgtcg gaccgctgct ggggtcgctg ctccggccgg tcggcgggcg
    13861 gctggcggac cgcttcggcg gcgcccggat cacgctgggg accttcgcgg cgatgggcct
    13921 ggccaccggc gtggtcatcc gcgcgtcggc ggaccactcg ctgccggtgt tcctcgtcgg
    13981 cttcttcgcg ctgttcgtgc tgtcggggct cggcaacggg tccacgtaca agatgatccc
    14041 ggggatcttc caggcccagg cgctgcgccg cggcctggcg ggcgaggcgg ccgcggccta
    14101 cgggcggcgg ctgtcgggcg cggcgatggg gctgatcggc gcggtgggcg cgctcggcgg
    14161 gctggccatc aacctcgcgt tccggcaggc gttcctgacg gccggctccg gcaccccggc
    14221 cttcgtctcc ttcctggtct gctacgccgt gtgcgccgcg gtgacctggg ccgtatacct
    14281 gcgtcccgcc gcgcgggagc ggcgtgccgc gcgggccggg gcggccgggg cggccgcgga
    14341 gggggagcgg cgcgcggtcc acgcggaggt gtgaggcgcg cggcgtaacg gtgcggaaat
    14401 actggaggac ccgggctgtc acctgccgtt ggcagtctgg gcaccttggc actccgtgcc
    14461 gcccgagccg cggcggccgg gctgcggaac gcggcacaac cactctgggc ggagcgggac
    14521 gaccatggac gagcagcatc aggggcgcgg ggagcgggag cggacggagc cgggcacggc
    14581 accgggggtc cggccgctgg acgggttcac catcggggtg accgcggccc ggcgggcgga
    14641 ggagctgggc gcgctgctgg agcggcgcgg cgggcaggtg ctgcacgccc ccgcgctgcg
    14701 catcgtgccg ctgccggacg acaccgagct gctcgcggtg acccgggcgc tgatcgacga
    14761 cgcccccgac gtcgtcgtgg ccaccaccgc catcggcttc cgcggctggg tggaggccgc
    14821 cgagggctgg gggctgggcg aggcgctgct ggaccggctg gccggggtgg agctgctggc
    14881 gcgcgggccg aaggtgcgcg gcgcgatccg ggccgccggg ctgaccgaga agtggtcgcc
    14941 ggcctcggag tcgatggccg aggtgctgga ccggctgctg gaggagggcg tcgccgggcg
    15001 ccggatcgcg ctgcagctgc acggggagcc gctgccgggg ttcgtcgagg cgctgcgggc
    15061 cggcggcgcg gaggtcgtcg gcgtccccgt gtaccgctgg atgccgccgg aggacctcgg
    15121 tccggtcgac cggctgctgg acgcgacgct cgccggcggc ctggacgcgg tgacgttcac
    15181 cagcgcgccg gccgccgcct cgctgctgcg ccgcgcggcg gagcgcggca tccgcgacgc
    15241 gctgctggcg gcgctgcgca cggacgtgct gccggtgtgc gtggggccgg tgaccgcgct
    15301 gccgctggag gccgaggacg tccccacgct gcagccggag cgcttccggc tcgggccgct
    15361 ggtgcagttg ctgtgccgcg aactgccggg ccgggtacgg ccgttgccgg tggccgggcg
    15421 gcggctggag atccgcgggc acgccgtcgt ggtggacggc gtgctgcggc cggtgccgcc
    15481 ggccgggatg gcgctgctgc gggcgctggc ccgccgtccc ggctgggtcg tcgcccgcgc
    15541 cgagctgctg cgcgcgctgc cgggcgcggg ccgcgacgaa cacgcggtgg agaccgcgat
    15601 ggcccggctg cgggtggcgc tgggcgcgcc caagctgatc cagacggtcg tcaagcgcgg
    15661 ctaccggctg gcgctggacc cgcacgcgga caccgacaag tacagcgggg aggacacgca
    15721 ggtcaggagg gtcgcgccgg gttgctgacg cggatcttgg actggccgtg cggccgggtc
    15781 tcccagtcgt ccatgaagcg ggcctccagg ccgtgcccgc gggccagccg cagcagggtg
    15841 tcggtccggt agtagaagtc ctcgcgcagc acctggtgct cggtgccctc ggtgcggtcg
    15901 aaggtgaagt cgaagaagcc gccgggggcc aggatccggc cgacgtgcgc gaggcactcg
    15961 tcgatcacgt cgagcgggga gtgcgagaag acgctgtgcg cgtgcaccac gtcgaagtgg
    16021 ccggccggca ggaagtccag cttcaggtcc tgcgtgatcg tcaggtgcgg cagcttgtcc
    16081 tggagttcgt acgtcgtcag ggtgcgcttg gcggctatca ggatgtccgg cgagatgtcg
    16141 atgccgtagt agttgccggt gtcgaggtgg gcgatgaagc gccagccggc ccgcaggttg
    16201 ccgcagccga tgtccagcat ccggtgctcc ggccggaggc cgtgcccggc caggtaggcg
    16261 aactgcatct cgcccagcgc cagccaccgc tcgtggctgc ggctgcccac cgcggcctcg
    16321 gggctgcggc cggtgtcgga ggccatcacc gcccggtagt acgcgacgtg gtcggggtgc
    16381 ttgaggcgca gccaggtgtc gcgggcggtg cgcttgacgt acggggtgat gcgggcgggg
    16441 ttgcggaccg cgtagccgat cttgtgggtc aggctggcgc ggttcgtgag cagggacttg
    16501 cgcgacatgg agaccttcgt cctggagggg caaagacgtg cggtgacgtg cggggcgggc
    16561 cggtgcgcgg gccgcgggcc gacccgccgc ggactataca tcaggtgtat acgcacagag
    16621 tctacttgcg gtgtctaccc gtgggacccc cggtgtccgg gcgcggcggg cccccggggc
    16681 gcccgcgccg cccgccgtac ggagtggccg cctccggagg gttccgggcg ggccgcgcgc
    16741 cgggcactct gggagcacac gcgtttggtt cctaaggagt gacaggcaca tggcagcggc
    16801 gtgcgacctg cggttcgact gcggccggac ctgcctggac ctggtggcca cggccggcga
    16861 cgcgcccgcc gaacggctca ccggccccga gcagttggcg gcctggctgg tcggcgcggg
    16921 gctggtgccg cgcggcgtcc cgctggacgc cgtcgacggc cgctgggtcg tccgcttccg
    16981 ggcgctgcgc gacctggtgt gccgggtggt gcacgacgag ctgcgggacc gggcggccga
    17041 cgccgacctg gaccggctca actccgcggc cgcggccggc ccgccgcccg ccccgcgggc
    17101 ggtgcgcggc gccgacggca ccctggcccg tacgctctgc gccccgcccg actgcgccgg
    17161 gctgctggcc gcggtcgccc gggacgcggt cgggctgctc accgacccgg tggcgcgcgg
    17221 gcagttgcgg cagtgcgcgg gcgagcactg ctcgctggtc tacctggacg gctcgcgcgg
    17281 gcggcgccgc cgctggtgct ccagcgaggt gtgcggcaat cgggagcggg tggcgcgcca
    17341 ccgcagacgc tcgaccgtgc gcggggcgac cggccccgcg ggcggccccg tcccctccgg
    17401 cgccgctccc ggaccggccc gcgtcccgtc gccggagccc gtcggcccgc cgcccgagcc
    17461 cgtcggcccg ccgcccgagc ccctcgcccc ggcctccgtc atgcccggga aaaattttcc
    17521 ggccggcggc tgagtgaccc gcccgtcccg tccgtactcc tcaccgcaag tccgatttca
    17581 tggccaggtc cccggcgatc ttgggtgatg cgggctatcg acccgggagt tggagtgcgt
    17641 aaggatgccg tcgtggcaga caggacgaca cctgacgagg agctcatgcg agccctctat
    17701 gacgagcacg cgggcccgct cctcgctttc gtcctgcgac tggtggcggg cgaccggcat
    17761 cgcgcggagg acgtggtgca ggagacgctg gtgcgcgcct ggcgcaacgc cgaccagctg
    17821 cagcgggcca ccgggtccat ccgcccgtgg ctggtgacgg tcgcccggcg gatagtgatc
    17881 gacggtcacc gcagccggaa ggccagaccc caggaggtcg acgcgacacc tctggagacg
    17941 atgcccgccg cggacgtgat cgaccgggcg ctgcgcatga tgacgatctc cgaggcactg
    18001 agcgacctga gccaggccca ccgagaggcc ctcgtcgaga cgtacttcaa ggagcgtacg
    18061 gtcaacgagg cagcggaggt gctgcgcgtg ccggccggaa ccgtgcggtc ccgggtcttc
    18121 tacgcgctgc gctccctgaa gctctcgctt caagaacgag gagtgacgga gtgatcccgc
    18181 ccacgcagcc ggaccggcac accgacgtcg gcgcctacgc gctgggcgtc ctggacgccg
    18241 ccgacgcgga acggttcgag gcgcacctgg tcggctgcga ccggtgcgcg gccgaactgg
    18301 aggagctgat ggggctcacg cccgcactcg ccgagttcaa ggagtccgcc cccaccccgg
    18361 agaccctcac cgccgttccc ggcccgcggc tgctgaacgg actcctcgac gaggtcgccg
    18421 ccacccgccg cggccgagcc cggcgccggc tgttcctggt cgccgcggcc gtcgtactga
    18481 tcgtcggcgg accgctcgcc gccctctccc tcaaggggga cgccgacgcg ccgccggccg
    18541 cggcgccgcc gctggcgaac gccgtgcgcg cccagtacgc cgagggcgag aaggccggct
    18601 ccgtcgaccc ggtcaccaag gtctccgccg gtgtctccat ggcgccgcgc ccctggggca
    18661 cccaggtcgt cctggaactc gccaacgtca agggaccgct ctcctgcgac ctggtcgccg
    18721 tcggcaagga cggccggcgg cagaccgtca ccacctgggc cgtgcccaag ggcggctacg
    18781 gcatccccgg cagcgccgcc aagtggaacc gcgagcccct ctacgcggcg ggcggcgcgg
    18841 ccctcgaccg cgccgacatc gaccacttcg agatcagcac gctggagggc aggcgactgg
    18901 ccaccgtgaa ggtctgagac gcccgaagtg acgatctgac gcaacatccg acggaatctg
    18961 cggaaatctg cccgattttg tccctctcac caggtgcgca cggtgcccgg ttcgcgtacg
    19021 gttgacggct gccctacgca cagcagaagg gggcctgggt ggccgcgcac aacgccacgc
    19081 acgcaccgga ccacgcaccg gattccgttc gcgaccgcga gatcgaggcc gagcagacgc
    19141 atctcgaccg cgtctaccgg cgccttgagg agaagatcca cgaggccgag ttcctgatgg
    19201 acgacgccgc caagcgcggc caggtcggca cgcccggcgc gctcgccgag cgggacgccc
    19261 aggtcttcca ggccggagtc cacctccacc ggctgaactc cgagtacgag gacttcctct
    19321 tcgggcggat cgacctgctc ctcggcaagg acggcaagaa gggcccggac ggcgcgtaca
    19381 cctcggtcga gcccgccgac ggcgccgtcg agaacaaccg cgcgacgatc gccgagacgc
    19441 tgcacatcgg gcggctcggc gtcctcgacg cggactactc cccgctggtc atcgactggc
    19501 gggcgccggc cgccgcgccc ttctaccgcg ccaccccggt cgcccccggc cgggtcgtcc
    19561 gccggcgggt gatccgctcc aagggccgcc gggtcctcgg cgtcgaggac gacctgatgc
    19621 gcccggaggt caccgcgacg ctggacggcc gcgagctgcc ggcgatcggc gacggcgcgc
    19681 tgatggccgc gctcggccgg gcccgcagcc acaccatgcg ggacatcgtc gcctccatcc
    19741 aggccgagca ggacatggtc atccgggcgc ccgccgcctc cgtcaccgag gtcgagggcg
    19801 ggcccggcac cggcaagacc gcggtcgccc tgcaccgcgc cgcctacctc ctctaccagg
    19861 accgccgccg ctacgccggc ggcatcctga tcgtctcccc gacgccgctg ctggtcgcct
    19921 acaccgaggg cgtgctcccg tcgctcggcg aggagggcca ggtcgccatc cgcgcgctcg
    19981 gctcgctcgt cgacggcgcg gaggcgaccg cgtacgaccc gcccgcggtc gcccggatca
    20041 agggctcctc gcggatgcag aagctgctgc gcaaggcggc ccgcggcgct ctggagctgg
    20101 cggcaccgcc cgcgggcggc gtggcggagg acgccgggcc ggacacccag ctgtccctgg
    20161 aggacctcgt ccgggggccc gacgggccgg ctccccgggg cggcgcccgc cgccggaccc
    20221 ggggcggatc cgcccgtccc gcctccaccg cgcccgcccg gctgcgggtg gtggcgttcg
    20281 gcacccgcct cgaactggac gccgacgagc tgcacgccat ccgccagtcg gccctcggcg
    20341 gcaccgcccc ggtcaacctg ctgcgcccgc gcgcccgccg gctgatcctg gacgccctgt
    20401 gggccaagtc cggcgcgggc cgccgctaca ccgaccccga actcgccgcc gaggcccgtg
    20461 agggcttcga cgaggacctc accaccgagc ccgtcctcca ggaattcctg gacgcctggt
    20521 ggcccgagct gaccccgcgc ggcgtgctgg ctgcgatggc cgacgagcgc ctgctgagcc
    20581 gctgggcacg ccgcgtcctc aaccctcgcg aggtgcgcca actggcccgc tccctggggc
    20641 ggttggacgc cgccgggcag ggcccgctgt cggtgcacga catcgcgctg ctggacgaac
    20701 tccagcagat cgtgggcgcc ccgatgcgcc cggcccgtcc gcgcgaggcc gacccgctgg
    20761 accatctcac cggcctggag gagctgacga cctgggcgga ccgcaacggc ggcggccgcg
    20821 gccggcgcga acgcctggag gaggagcgca ccgactacgc ccacgtcatc gtcgacgagg
    20881 cgcaggacct gacgccgatg cagtggcgga tggtcggccg ccgcggccgg caggcgacct
    20941 ggaccgtcgt cggcgacccg gcgcagtcct cgtggtcgga ccccgacgag gccgccctcg
    21001 cccgggacga ggcgctcggc acccgcccgc gccgccgctt cacgctgacc gtgaactacc
    21061 gcaaccccgc ggagatcgcc gaactcgccg gcaaggtgct cgcgctggcg atgcccggca
    21121 tgcagtcgcc gaaggcggtc cgctcgacgg gcctgcggcc gcgcttcgcg ctcgccgggg
    21181 acggcgcggg cccgacgggc gacaaggagc tggagcgggc caccgtcgcg gcggccgggc
    21241 ggctgctgga cgaggtggac ggcacggtcg gcgtcgtggt ggcgatgaac cgccgcgagc
    21301 aggcccgccg ctggctggcc ccgctgggcg accgggtggt ggccctgggc tccctggagg
    21361 ccaagggcct ggagtacgac gccacgctgg tggtctcgcc cgccgagatc gccgacgagt
    21421 cgccggccgg cctgcgggtg ctctacgtgg cgctgacccg cgccacccag cagctgacgg
    21481 tgctctccac cgcgcgcgac gagccggacg ccgcggcggt gcccgacctg ctgcgggact
    21541 gaggcgttcc ccgtccggcc gccggctgtc cgccggtggc cgacggccgt ccggggggtt
    21601 gtggaaatcg gcgccgcggg acgggattcg cttccgggga tggtttgtta gcctgggtga
    21661 cggcaccggc tcgatccaag cccccgggcc caaccatcgt cgctacgagc gaccacttgc
    21721 cgcgaggcga gcatggcggg tcggtgccgt tgacgcagag aggtccacgc cactccggtg
    21781 gcgtggacct cttttctgtg cgcgatcatt ctcgtatggt ggaattcgtt ttccgaagat
    21841 gtcgtcgcgg gcgaacaaaa cgttcgcaat gcgaggcggc taccgcgtac tgcgcggtag
    21901 gtgcgacgat cggacggcaa tccagctaca cggtgaaagc agaggaagtc ggccatggca
    21961 acggcgccca gcgtctccta ctcgatgacg gtccggctgg aggtgcccgc gagcggaacc
    22021 gcggtgtccc agctcaccac ggccgtcgag tcccacggag gctcggtgac cggcctcgac
    22081 gtcactgcgt ccggacacga gaagctccgc atcgacgtca ccatcgcggc gacgtccacg
    22141 gcccacgccg acgagatcgt cgagcagctg cgcggcatcg agggcgtcgc cctcggcaag
    22201 gtctccgacc gtacgttcct catgcacctc ggcggcaaga tcgagatgtc gtcgaagcac
    22261 cccatccgca accgtgacga cctgtccatg gtctacaccc ccggcgtcgc ccgggtctgc
    22321 caggccatcg ccgacaaccc cgaggacgcc cgccgcctga ccatcaagcg caacagcgtc
    22381 gcggtggtca ccgacggctc cgccgtgctg ggcctgggca acatcggccc caaggccgcg
    22441 ctgcccgtca tggagggcaa ggcggccctc ttcaagcgct tcgccggcat cgacgcctgg
    22501 ccgatctgcc tggacaccca ggactccgac gcgatcgtcg agatcgtcaa ggccatcgcc
    22561 cccggcttcg ccggcatcaa cctggaggac atctccgcgc ccc
//
