LOCUS       NZ_CP012749            30097 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Rhodococcus sp. 008 chromosome, complete genome.
ACCESSION   NZ_CP012749
VERSION     NZ_CP012749.1
KEYWORDS    RefSeq.
SOURCE      Rhodococcus sp. 008
  ORGANISM  Rhodococcus sp. 008
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Rhodococcus.
REFERENCE   1  (bases 1 to 6570200)
  AUTHORS   Loewen,P.C. and Brassinga,K.
  TITLE     Genome sequence of a ureolytic Rhodococcus species isolated from
            skate fish
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6570200)
  AUTHORS   Loewen,P.C. and Brassinga,A.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-SEP-2015) Microbiology, University Manitoba, 418
            Buller Bdg, Winnipeg, Manitoba R3T 2N2, Canada
REFERENCE   3  (bases 1 to 6570200)
  AUTHORS   Loewen,P.C. and Brassinga,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-SEP-2015) Microbiology, University of Manitoba, 408
            Buller Building, Winnipeg, Manitoba R3T 2N2, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: smrtanalysis v. 2.3.0.140936
            Genome Coverage                   :: 176x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/04/2024 12:54:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,967
            CDSs (total)                      :: 6,896
            Genes (coding)                    :: 6,809
            CDSs (with protein)               :: 6,809
            Genes (RNA)                       :: 71
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 36 of 87
            Pseudo Genes (incomplete)         :: 58 of 87
            Pseudo Genes (internal stop)      :: 13 of 87
            Pseudo Genes (multiple problems)  :: 17 of 87
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:00:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2359535
            Orig. end                         :: 2389632
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP012749.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Source bacteria are available from Dr. A. K. Brassinga, Dept of
            Microbiology, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..30097
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="4"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..30097
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..30097
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:20097]"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..20097
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            complement(283..1263)
                     /locus_tag="AOT96_RS11055"
                     /old_locus_tag="AOT96_11055"
     CDS             complement(283..1263)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735876.1"
                     /locus_tag="AOT96_RS11055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11055"
                     /product="proline dehydrogenase family protein"
                     /protein_id="WP_065351737.1"
                     /transl_table=11
                     /translation="MNTDLQAQAADVLRRLALDESLKERTMADAATAALARKVAARYIG
                     GETIDDAFDRLPSIFARGHKASIEYTGESVRDPELANAETDVFVELAERIGTSGVESTV
                     SFDLSHIGLVIDPEQCFRNVVRLAEATERAGAELIISAEASDRTDLVLDMHARLAERFT
                     HVGITVQARLHRTAKDLAALLDRPGRIRLVKGAFLEAESVAYPRGSAELRSAYLDYAAR
                     IVESGHQVSIATHDRDILEALRAEHDSKLRGEHVEFEMLLGLGTEQLDALRGAGFTTRE
                     YVIFGTQWWLYVLNRIAEEPERVYTALIDAASTEPRMVVGSMEPR"
     gene            1425..1685
                     /locus_tag="AOT96_RS11060"
                     /old_locus_tag="AOT96_11060"
     CDS             1425..1685
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943561.1"
                     /locus_tag="AOT96_RS11060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11060"
                     /product="hypothetical protein"
                     /protein_id="WP_065351738.1"
                     /transl_table=11
                     /translation="MAAEARIVDTVSVEDSRASAPRVASKTEQKDAPKADAVAKVSANL
                     VVLTSADLVVPTSVDTVGRALVKPAQRSVPRWVYSEVPLLR"
     gene            1652..1831
                     /locus_tag="AOT96_RS11065"
                     /old_locus_tag="AOT96_11065"
     CDS             1652..1831
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019746296.1"
                     /locus_tag="AOT96_RS11065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11065"
                     /product="hypothetical protein"
                     /protein_id="WP_019746296.1"
                     /transl_table=11
                     /translation="MGLLRGAAVAVAAGGTAEQVAKAEAILAEARRALFEMLAEKPADV
                     QQAHAESTDTLPAE"
     gene            complement(1841..2656)
                     /locus_tag="AOT96_RS11070"
                     /old_locus_tag="AOT96_11070"
     CDS             complement(1841..2656)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /GO_process="GO:0055072 - obsolete iron ion homeostasis
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1200: vibriobactin
                     utilization protein ViuB"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943529.1"
                     /locus_tag="AOT96_RS11070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11070"
                     /product="siderophore-interacting protein"
                     /protein_id="WP_064073632.1"
                     /transl_table=11
                     /translation="MSFCEPARVVTVTSLTPHMRRISIEAEGDWHWPTGGQGDERIDLA
                     FPKPGETEAEYDYFNNPDYGKADLGTEPPWRHYTVRKVHDGGRRLEIDFVVHPGGIAAD
                     WALRAEPGHLLGVFWSDSSRSHYQAPAGPRWQLLVADATGLPGLGRIVEELREGDVAQA
                     IIEVETEEDRQEFVTRGDVTYTWLVGSGLGKAPSALFEAVEKVEFPESETADVYAWVAC
                     ESATSRRIRKHLREVRGIARDKHNVVGYWREGADGHVSGMNSEEVTVGA"
     misc_feature    complement(2614..2629)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            complement(2801..4039)
                     /locus_tag="AOT96_RS11075"
                     /old_locus_tag="AOT96_11075"
     CDS             complement(2801..4039)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019745836.1"
                     /locus_tag="AOT96_RS11075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11075"
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="WP_065351739.1"
                     /transl_table=11
                     /translation="MDSREAWQLDGEDLKSEVLDLVRVRHELQSRMVLLIVEMFSRDVL
                     GGKGFRAIAQWLHGSTNLEIGECSLLVGLARLLMLEPVVADAFHRGDVDALKARQVASF
                     CQHPPKNMTLADVDKARGILLGLASKNIADCDAVRAAIRRIEKQYGKREDGVPVGEDSE
                     RNEFYASKGLYGRVSVKGDLDAVNGARLITLLSSLSAPTPEKDGVKDTRTPALRRADGF
                     CELLRRYERAGLGPIEGGVKPHITVTASAKDMTDLQALKDLLPSTEELGFAWADWVGPI
                     SIDTARMLACDCTVTRILLDENGVPLDCGKEARTATVPQRRALAVRDGGCAFPGCGTPS
                     GWCDAHHIVHWNDGGPTDLDNLILLCGHHHRTLHHTEWRVEIGPDRKSVFYPPMSIDPY
                     QQPIGGNSPPTAA"
     misc_feature    complement(4053..4068)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.95"
                     /tool="antismash"
     misc_feature    4054..4067
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.58"
                     /tool="antismash"
     gene            complement(4132..4749)
                     /locus_tag="AOT96_RS11080"
                     /old_locus_tag="AOT96_11080"
     CDS             complement(4132..4749)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015652325.1"
                     /locus_tag="AOT96_RS11080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11080"
                     /product="response regulator transcription factor"
                     /protein_id="WP_003943536.1"
                     /transl_table=11
                     /translation="MIRLLLADDHAIVRAGLRALLESEADIEVVGEAGTAEEAIAFCAT
                     TPVDLVLMDLRFGPGKTGVDATRAVCALPNPPHVLVVTNYDTDADILSAVEAGASGYLL
                     KDTPPVELLSAVRAAASGDSVLSPAIASKLMTRVRKPETSLSPREIEVLKLVAAGRSNR
                     EIGKELFLSETTVKSHLVHIFGKLGVKSRTSAVARARELGSI"
     gene            complement(4746..5948)
                     /locus_tag="AOT96_RS11085"
                     /old_locus_tag="AOT96_11085"
     CDS             complement(4746..5948)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943587.1"
                     /locus_tag="AOT96_RS11085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11085"
                     /product="sensor histidine kinase"
                     /protein_id="WP_064073630.1"
                     /transl_table=11
                     /translation="MDERGPNLAKLGEMHRSPLTPVFAGLQLGLHVLVMALAGVVFLRA
                     LLDESDLTATIIALAVIFVAVYLFGVAKRLRGNAARWWLAVLTLVWIATMAVSADAAYL
                     AFGLFFLYLHILRRPWSLLAVTAATAVAVVGTGLHRGWTIAGAVGPIIGAAVAVAIGLG
                     YQALYREAAERGRLIDELMNTREELASTSRDAGKFAERERLAAEIHDTVAQGLSSIQML
                     LHAAERADPDSPAIRQISLARETAADSLAETRQLIAELTPAALDGQSLADALRRICERA
                     SSPELEARSVVEGEAVRLPMPLEATLVRIAQGAVSNVLRHADATRMAVTLTYSDDTVSL
                     DVVDNGHGFDVAVLERGPAESFGLNAIRRRVELQGGTFSIESEPGHTAVAVTFPLEVGE
                     P"
     misc_feature    5947..5962
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 20.61"
                     /tool="antismash"
     gene            6063..7109
                     /locus_tag="AOT96_RS11090"
                     /old_locus_tag="AOT96_11090"
     CDS             6063..7109
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012691027.1"
                     /locus_tag="AOT96_RS11090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11090"
                     /product="ABC transporter permease"
                     /protein_id="WP_039973533.1"
                     /transl_table=11
                     /translation="MFVAMRDLRAARGRFALISVVVLLVALLVSFLSGLTAGLRHQNVS
                     AIEAMNADTVVFADTGAGASFDESALTQDQVNAWTSTSKDVDPIGIGRGKAGLADGNQK
                     SVALFGADGGFGDVTPSASGTVVLSEGAARDLGAGAGDQVSVGTQQFTVSAVRGDDWYS
                     HSPVVWMTLDDWQAANPRGGVATVLAVTGASDASATDKAAATTSTTVSGSLDAIGSYKS
                     ENGSLTLMTLMLFAISALVIGAFFTVWTIQRTPDIATLKALGATTGSLVRDALGQALIV
                     LIAGVTVGIGLTAVAGSLIGDAMPFVLDASTTVVPAVALIGLGLLGAAFALRFLSTTDP
                     LTALGSAR"
     gene            7106..7846
                     /locus_tag="AOT96_RS11095"
                     /old_locus_tag="AOT96_11095"
     CDS             7106..7846
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943539.1"
                     /locus_tag="AOT96_RS11095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11095"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_003943539.1"
                     /transl_table=11
                     /translation="MTMTTGTTVLDIQNVDLTFPDGQSRVTALDDVSLRLHRGEIAAIT
                     GPSGSGKSSLLAVASTLIRPDSGHVYLRTPEGSTDIAALSRRAASELRRSSIGIVFQQS
                     NLVSSLTALEQLEVMAHLGQSVFTSRARRKAVKSKAMDLLDAVGLADQSGKRPSQLSGG
                     QRQRVNLARALMNDPQLLVVDEPTSALDQERGAAVMDLIIGVVREREAATLLVTHDRSH
                     LSRMDTVYRVVDGSLAEDQEALAA"
     gene            7958..8398
                     /locus_tag="AOT96_RS11100"
                     /old_locus_tag="AOT96_11100"
     CDS             7958..8398
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943598.1"
                     /locus_tag="AOT96_RS11100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11100"
                     /product="PAS domain-containing protein"
                     /protein_id="WP_003943598.1"
                     /transl_table=11
                     /translation="MERRRNVAQPPQSPIADLEQMPALILLDRLPVPVMAVHRDGSIVF
                     ANPSFADMLGYPKKAVSALRLQDILYDKDADDVSAEQAHRELSSEPGSVKEFVHSDSTL
                     VRATVSQSLLRRDDDTITLAVLHDLTERLWNNPRHIDDKPTK"
     gene            complement(8405..9031)
                     /locus_tag="AOT96_RS11105"
                     /old_locus_tag="AOT96_11105"
     CDS             complement(8405..9031)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943606.1"
                     /locus_tag="AOT96_RS11105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11105"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_065351740.1"
                     /transl_table=11
                     /translation="MTEVLREDMSARRKIIEAAREVFVDPGYAAATIKQLAAAAGVSVQ
                     SVYFVFGNKPSVLSALLDVAVAGDEEKTATLDRPWVAAALGAPHPLGQLRIQVHHGRLI
                     LERTADILLALRAAASADEDAARLWQINRTQRRTVQEHLMVGIVEKAPTVDLETAVNVA
                     LTLLSPETYTDLVVGAGWTGQQYEEWVVNTLAATLGLDRTVKSRK"
     gene            9083..10054
                     /locus_tag="AOT96_RS11110"
                     /old_locus_tag="AOT96_11110"
     CDS             9083..10054
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019746304.1"
                     /locus_tag="AOT96_RS11110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11110"
                     /product="sugar nucleotide-binding protein"
                     /protein_id="WP_037126088.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.9e-05, bitscore:
                     20.8, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKVLVLGGYGAVGIPLMKQLAKVPEISAYSAGRDPARADVVVDL
                     KEPGAYSTVVRDFDVVVNASGFEDVRLADEAVRGGAAFVDVTATSNYCEELEAVDGPVL
                     MGVGLAPGLTSVLAAEAHRLGGGPVDIVIGLGGGELHGPAATAWTYGMLGTRFPDPDGR
                     SIRNYTGMKTFRIPADATGYRTGPAVRADFSDQHALTRDLGVPVRTYLRLDTSTATLGL
                     AAMTWAPALQKVVPKKLWGSDRWVAMARADTGPALWVSGRSQSVATAAIAARAVQVIRD
                     AAISKPTWFHAVETTESLQAAVPELSVRQWDGASRSSGKTVH"
     gene            complement(10001..11293)
                     /locus_tag="AOT96_RS11115"
                     /old_locus_tag="AOT96_11115"
     CDS             complement(10001..11293)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943528.1"
                     /locus_tag="AOT96_RS11115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11115"
                     /product="YcaO-like family protein"
                     /protein_id="WP_065351741.1"
                     /sec_met_domain="TIGR03604 (E-value: 1.1e-65, bitscore:
                     220.4, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 6.1e-50, bitscore: 169.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSLVDRRTGIIRELVDAVVPQHFPPEFKLIHSYVSDSARFSPW
                     SSDSAGAGYCFDLGDRARPTAAAIGEAVERYCGNIVAKPIVRGSADALIGASIDLSQLA
                     RFDAAQCARPQFPFVEPTDDLEMDWTRGADLITGSDIWVPAELVWGSYPHFVARTGPAI
                     SPVAQAGLAAGPSVKFAIDNALREIVERDAMTLSWTGRRGVRVVTGIPEVLRRLGNHGT
                     LSTRWLSFDSDFGIPVLGALIHDGLTGYSTIGTACHEDAQTAAFKSLGEALQLQLLSAD
                     YDNPQSGIGRAAASPTSPLAHWRADRSYAGAYRSDFADVMDYGCHLQLHLDPEIQARFE
                     SELVGAVVGEVGLDSLTSAAGTESALTAAGFRPAWVDLTTTDVLHAGLHVVRVVVPGCL
                     TNAAAGLPFLGSPRLVDSLAGRSARTIPLPH"
     gene            complement(11290..12630)
                     /locus_tag="AOT96_RS11120"
                     /old_locus_tag="AOT96_11120"
     CDS             complement(11290..12630)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943577.1"
                     /locus_tag="AOT96_RS11120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11120"
                     /product="YcaO-like family protein"
                     /protein_id="WP_042453284.1"
                     /sec_met_domain="TIGR03604 (E-value: 2.6e-71, bitscore:
                     238.9, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 7.1e-64, bitscore: 215.1,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDLLVDARSGVLTSLEPHIRSDMPTGWVGWAARVADTRNFGGSG
                     SLFRADPYGFGASIRDDAAARGAATGEAVERYCGNVVPEDLVRSSASALELAGSRVVDP
                     AEFALYSEDQYRLPGFPFVPFTSDLNIRWALGHTMDEKVPTYVPAALTYLGYYTGTRRC
                     EPPIASLQYAGIAAGRSRDEAEMSALLELLERDATALWWCGDRSQPAIELSDWERLPAH
                     RQLGDLESQTRSVRVLLLPSPFGIPVAAAWIRDDRRGLVALGTACRPTVEAAVSKALVE
                     AYAVLAITIDLADPDGPTWRSVADGTLPAHLYKPFRADRRYRDEFDPQWKDIVDLPTVA
                     QLYLDPVMALAAEEHLFDYTETLSVSEIPDEAPLDLASLVALLMSRGHQPISVDLTTGD
                     ISIAGLHVVRILTPGLYNNAPAAFPLLGGSRLTSASTTHLHLPVPLA"
     gene            complement(12623..14053)
                     /locus_tag="AOT96_RS11125"
                     /old_locus_tag="AOT96_11125"
     CDS             complement(12623..14053)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735890.1"
                     /locus_tag="AOT96_RS11125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11125"
                     /product="CocE/NonD family hydrolase"
                     /protein_id="WP_065351742.1"
                     /transl_table=11
                     /translation="MISLGVKIPAADGSSLATDVLLPPDSSPRGLIVIRTPYGRGWHLA
                     EGIEWRLRGIAFISQDVRGRHDSTGSWEPYVHEREDSAALAEWLQDQPWTPECVIASGA
                     SYAAGTAWAFAAETNSADRSFRVDGVVSKVPTIGSDRVKRDPSGILLLAEHLAWWGEHG
                     DSSSSREGFIPALMRSDSSLLEHLPVQSMIEEVGLTSDSPGWLTAILRARKREDFGGDD
                     LVSADELSELDIAGLHIGGWDDAMIRETLRHFTSVGRGPQSLIVGPWAHDLRPGMVGET
                     SFGRLQVEWMESIFSARPVTINRVFDRGAGDWSSEPYVTGANRVRLEPDRKDAVYTFLY
                     DASRARNDCVFWTFDIKHDSVLSGTPSVELKVHSPEGEADWIVELSVVDAAGVTRSIAR
                     GAGVSVQPTMVTIDLDPVLHTVRAGDVLTLRIAGSDFPRLARNLGDGDRYRGTRSTALH
                     QSFSGSLTLPILGGTAGG"
     gene            complement(14050..14862)
                     /locus_tag="AOT96_RS11130"
                     /old_locus_tag="AOT96_11130"
     CDS             complement(14050..14862)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943559.1"
                     /locus_tag="AOT96_RS11130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11130"
                     /product="hypothetical protein"
                     /protein_id="WP_065351743.1"
                     /transl_table=11
                     /translation="MYALADGHQLYPTPDGTWHYLTPDENAVTIGAPAEDLAELDNFLR
                     RSGSVLGPGAIEIADALVSRGVLVVPGQAPEIPRPQRVLMDGIGPVADACIALLSKALP
                     HLEVVSTTAPIEDDVASSDLVLSVAGAPPHDEWSELDTWCRRNQTPWQTVHAELGEICI
                     GPFFDGIGSASYRDVCGRRLAASRVPDHLQALWNHLAGSEPRPLELEPTAAAMASALAC
                     SDVVAGVHGAPPSHLHHQIRMNPRTLMMTRHPVLPLPGGVLEPAPTLR"
     gene            complement(14957..15145)
                     /locus_tag="AOT96_RS11135"
                     /old_locus_tag="AOT96_11135"
     CDS             complement(14957..15145)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007536315.1"
                     /locus_tag="AOT96_RS11135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11135"
                     /product="streptamidine-related RiPP repeat protein"
                     /protein_id="WP_003943543.1"
                     /transl_table=11
                     /translation="MSNISFDSVSNSAPANALQGVGTNALVDNPFTFEPVAEATSAHAL
                     QGVGTNALVDNPFSFQS"
     misc_feature    15161..15176
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.99"
                     /tool="antismash"
     misc_feature    15163..15177
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.67"
                     /tool="antismash"
     gene            15238..16497
                     /locus_tag="AOT96_RS11140"
                     /old_locus_tag="AOT96_11140"
     CDS             15238..16497
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943579.1"
                     /locus_tag="AOT96_RS11140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11140"
                     /product="MFS transporter"
                     /protein_id="WP_065351744.1"
                     /transl_table=11
                     /translation="MSETPTTGSVEAQPHVFRDRSFRLFFTARTIAVAGAAVTGVAMPI
                     LVFDISRSPFLTSLAAAGTVLPYLVFGLFAGAVADRVNRRTVILCAQAVAALALASIPA
                     AQALGVLTAWHAVGVSMCIGTCFVWFDAAAFGALPALVGRQRIPAANSALWTSSTLIDV
                     VFPAIAGVLVASIGPAYALGADALAYVLAGLAMASIGASFSITPAAPKKSGTGIARDIR
                     EGLSFLWRSPLLRALTGVGFVNSLTQGAVTALLVVYASERLGISTSSPMIGAVWTAVSV
                     GGVVGALVLPRLPAQWPVGAITVGALTIAPVVLFVVATTGNAGAAITALVVYSGCATVT
                     ILNGIGARQRLTPDRLQGRVNTTARMVAWGGSPVGALIAGAIAGRWDIGTAYLVACIFA
                     LVGALFAWASALRTDPYPHK"
     misc_feature    16511..16526
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.75"
                     /tool="antismash"
     misc_feature    complement(16513..16527)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 20.78"
                     /tool="antismash"
     gene            16582..17649
                     /locus_tag="AOT96_RS11145"
                     /old_locus_tag="AOT96_11145"
     CDS             16582..17649
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735896.1"
                     /locus_tag="AOT96_RS11145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11145"
                     /product="iron ABC transporter permease"
                     /protein_id="WP_064442931.1"
                     /transl_table=11
                     /translation="MTLTSEAAPRVPSRPHPVGERGYVPFLLATAVVLVAVSTVAVWSG
                     AASVSFADVFAVLYAHVGGPPVDPLLDRIVWGLRVPRILIAALAGAGLSLAGAVLQALV
                     RNPIADPYILGVGSGASFGAVLIMTTGIGTSLSIGVPVAAFLGAMVSLIAVLVLGRREG
                     MLVPLRMVLAGVAIGYLLSAATSFVQLRADPSQLSGVLFWLLGSVSGASWSDLGVPAAV
                     ITVCAAILLTQSRQLNALAMGDESAQSVGVDVHRTRLLLLVIASLLTAVVVSVAGGIGF
                     VGLLVPHAVRLLVGSDHGKLLPATALVGATFLVIVDLAARMLDAPNELPLGIITAGLGA
                     PFFLWLLRRDGGAQS"
     gene            17646..18440
                     /locus_tag="AOT96_RS11150"
                     /old_locus_tag="AOT96_11150"
     CDS             17646..18440
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019746313.1"
                     /locus_tag="AOT96_RS11150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11150"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_042453274.1"
                     /transl_table=11
                     /translation="MRLSASGIHVVRGGRLVVSGVDLEAPEGSVVGLVGPNGSGKSSLL
                     RALYRSMKPRSGIVKVDEVNVWDDLSPRSAARIIGVVGQEHSSDFSFSVREVVATGRTP
                     HHSAFSRLGEIDRDIVSAALVRTGMQGFGSRLFAELSGGEKQRVMLARAIAQQPSVLVL
                     DEPTNHLDIRAQLELMELVAELGTTTIVAIHELALAAAYCDYVCLLSGGVVVATGPTAE
                     VLTEDLLSEVFGVQVHLGTHPLTGRPLLSFAPPLLHTKEAVS"
     gene            18437..19417
                     /locus_tag="AOT96_RS11155"
                     /old_locus_tag="AOT96_11155"
     CDS             18437..19417
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735904.1"
                     /locus_tag="AOT96_RS11155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11155"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_064442933.1"
                     /transl_table=11
                     /translation="MKSSIRTAALLCSAVTATAVLTACGNSTADSAASSSEKITVTNCD
                     REVTVPKTAERIVSLYPSMTELLIQLGAADRIVGQSNTDLSPPSPELADQFAAVPVLST
                     GVPAKEALLDARPDLIVSDGEYWFDGDRLQTMDELRDLGIPIFVNSGYCHKAVTEGRID
                     DVWSDLDGLGALTGTSDAAATLLADGKKSLAATEASVAGQEPVPTVMVQVSEGQSYALA
                     RGLYSSVLEAAGGSNLFENDLPDGKYFGQVATESVLAKSPKAVLVVYSTESARESTLDA
                     ARTAFAGTPAATSNAIFAVPEAWFAGELVSIDGAGEVSRLLHPGS"
     gene            19414..20097
                     /locus_tag="AOT96_RS11160"
                     /old_locus_tag="AOT96_11160"
     CDS             19414..20097
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735907.1"
                     /locus_tag="AOT96_RS11160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11160"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_065351745.1"
                     /sec_met_domain="PF00881 (E-value: 2.6e-18, bitscore: 65.1,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTALERIEAVVSLHAVLDRTVSPSELPFDEHALPPVTCESVELPA
                     ATPLPACGFADVLQARRSRYDPAQTALRAGELSNVLHHSLVSSPTAGGMRELTLSFVLS
                     RPGDELGAGVYRYARGRAEAVRPGDVREHLRASLLQPEFVDVFPVLLFVVADVEAPLEK
                     YAMRHYRTMHVDAGVLVQNLYLMTEAMGLAGCAIAGFTDARVASLLNLATTQLPVMAFA
                     LGRRS"
     gene            complement(20099..20383)
                     /locus_tag="AOT96_RS11165"
                     /old_locus_tag="AOT96_11165"
     CDS             complement(20099..20383)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735909.1"
                     /locus_tag="AOT96_RS11165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11165"
                     /product="SHOCT domain-containing protein"
                     /protein_id="WP_007735909.1"
                     /transl_table=11
                     /translation="MSFLRRAGRVAVASSIHGNVQRRQRTRWAAEDQARAAQAQPVPPI
                     PDLPPLPPQAAPAASMDLKLEQLTKLGELKNAGVLTEAEFETQKARILA"
     gene            complement(20380..20832)
                     /locus_tag="AOT96_RS11170"
                     /old_locus_tag="AOT96_11170"
     CDS             complement(20380..20832)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943563.1"
                     /locus_tag="AOT96_RS11170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11170"
                     /product="DUF6325 family protein"
                     /protein_id="WP_064442936.1"
                     /transl_table=11
                     /translation="MSNQDQFGPIEYVAVEFPGGAPTSAGFEQLLALVDSGVIRILDLE
                     FVTKAADGTVSVVPASTFELADFDLAQFDGAASGLLDAGDIAAVGDELATGSVAAVLVY
                     EELAILPVIDAWTRSGAKIVTEGHLSLDELATALDNTAPGNTEKDA"
     gene            complement(20836..22482)
                     /locus_tag="AOT96_RS11175"
                     /old_locus_tag="AOT96_11175"
     CDS             complement(20836..22482)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943582.1"
                     /locus_tag="AOT96_RS11175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11175"
                     /product="MFS transporter"
                     /protein_id="WP_003943582.1"
                     /transl_table=11
                     /translation="MSVKPGAAATTAAVSTASWLPLIVVVLTQIQASFAVNALTVSMAG
                     ITTDLDTPATSVGTAITAGTFAMAAFILLGAKIGARYGTRLVFQIAVAIHGLAMAAVAL
                     SQSPAMLFVAQAASGAVIALIAPALTVFIATNFSGDQQAKAIGYLAAAIPAAGVLALLI
                     AGSFATTIGWRYSFALVVALAVVNLILSFRVKPVPPQKDITIDWAGAAIAAVAVILLSF
                     GFSGLNSWGVILATDAAPFSVIGVSPAAILIVLGTICAQGFFQWTRSRKAQNKPQLFNL
                     DVLKTGAERATTICMATMMFVGTAANFLIPLYMQIIQGRSSLQTSFSIIPYTLSIFIAS
                     TVVARLYKTYSPRLIARAGFVVVAAGLILLAFTIRGDWHQIFVVIGLITLGLGQGAIVA
                     LVFNTLLTAAPKELAGDVGAWRGLVHNMSGSVGIAVASVFAVGILGSLVSSQLIDNPTI
                     PASLKVESGINLDQVNFVPNDQLVVTLENTSATQAQIDEAIRINTEARLRALRTSLLVL
                     AGLSLLAIIPAGRMPNEVPALEEPQPTKGKK"
     gene            complement(22551..23798)
                     /locus_tag="AOT96_RS11180"
                     /old_locus_tag="AOT96_11180"
     CDS             complement(22551..23798)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735921.1"
                     /locus_tag="AOT96_RS11180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11180"
                     /product="hypothetical protein"
                     /protein_id="WP_058227365.1"
                     /transl_table=11
                     /translation="MEQTLTAVEDLTEVASRAVAAERDARSVRWHNPAAVRKAAASVRD
                     SLDDERSALSRPSYSGLSPSPHMARQLELITTLQPPLPADAGIGTAAQAEADAVAAVTT
                     ARIALRAAHLAVLEARVAALDAGDTDTVAAAIRGYVPLNSGNPVVRHVQDLGSRIREEA
                     RHVVSGKPRSIAFRLGLSLGMGLAYLAFIRLFQWDTKEDRLPYLALYALSGVVGSVVCT
                     NALSFDAGRVRAALSGGTRLWHVLVAKNAVMLLLVGSAGFLLSAVLAWRSGSSADLVKA
                     CGQVLTMILLWLGVANVMSVSLPLRAEPMTARRHDGTWKQFLLSFVISYGVGLIVNLML
                     YWRVWAKTTLLEQMGGPWIPVLLLLASAAATWLLLTVLAVLLAEQPRFRRALHREMVVY
                     REETNHLQATIQHNSG"
     gene            23817..24404
                     /locus_tag="AOT96_RS11185"
                     /old_locus_tag="AOT96_11185"
     CDS             23817..24404
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019746321.1"
                     /locus_tag="AOT96_RS11185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11185"
                     /product="DinB family protein"
                     /protein_id="WP_003944177.1"
                     /transl_table=11
                     /translation="MTTNSEKEDLQRYLQAARDALVWKLDGLSEYDIRRPMTRTGTNLL
                     GLVKHMIGVELGYFGPTFGRRVPDLPAWLRSEELNVDMWARADESTADIVETYRRTWAF
                     ADATIEEHDLDAPGFVKHWPEDRRDVTLHRILVHVVTEIHRHAGHADIVRELIDGAAGM
                     KAGDNNLAPGDEAWWAEYTDRLETAAREAHHA"
     gene            complement(24406..25968)
                     /locus_tag="AOT96_RS11190"
                     /old_locus_tag="AOT96_11190"
     CDS             complement(24406..25968)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735924.1"
                     /locus_tag="AOT96_RS11190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11190"
                     /product="TRAP transporter large permease subunit"
                     /protein_id="WP_058038092.1"
                     /transl_table=11
                     /translation="MSTETDTGSAPTPAKKKFEFPGAVTMLAIVTILVWVAALFIPAGR
                     FGVDVDGSPVPGSFETVTSPLSFWERIQQLILSPVNGLYGVQDSITGFVDTDNIGRLFG
                     SVGVVLFIMALGAFISVSFATRSLETAVSQLATKLSDKGWLLITVIMVLFSLLGSTMGF
                     SVETFGFYALLIPLMTALGYDRMVAATMIILGALVGNMASTVNPFSIGVASGEAGVSIG
                     DGIVLRVILWIVLTAVAVAFVLRYAAKVKKDPSKSLVGFDIADDEDEEPAEPVDIDGKL
                     TGTQKLVLLITGLTFGLMIFSVIPWSSIFGATTGPAEYDAYHVTATEPYWFELNWWFPQ
                     LAMLFILAAVLVGIVAKMGEKKIVSLITRGAGDMVGPAIVILLARGVSVIMTNTETLDT
                     ILNAMEQLVSGASAGVFAILVMLVNIPLAFLIPSSSGHATLAMPLLAPLGDFAGVSRAL
                     VITAFQMGHGLMLMVAPTNVVVVGGLAMAKVGYDKFLRFVWPLLLINFVIVVVVIGAAA
                     VFE"
     gene            complement(25965..27341)
                     /locus_tag="AOT96_RS11195"
                     /old_locus_tag="AOT96_11195"
     CDS             complement(25965..27341)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735926.1"
                     /locus_tag="AOT96_RS11195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11195"
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="WP_030535870.1"
                     /transl_table=11
                     /translation="MPEESASPSYSTIKETVAALMPALESELVELVRIPSIATEGFPSE
                     PLFEAHDLIVSLLEKSGVTKIEKLEITGKTAPVIIATVPGPEGAPTVLMYSHYDVVPAD
                     DVELWDSPPFEPSKRDGAIYGRGTADSKANVIGMIGALRVFDGKPPVTVKLVIEGQEEF
                     GSPFDNYPPEAPELFAADAMVIADVGSVRPGSPTLTVALRGSAQVIVELTTLGADKHNG
                     LYGGAAPDARLALIRALASLHDDNGDVAIDGLLREPWTGSSYTEDEFRTLAEIQDGLPL
                     LGTGGIGERIWSGPAITVTGIDAPPVDGAVNAVASTARAVINLRVHPRQPAIEAQAALV
                     RHLEALRPFGLQLTVTAGETGDGFAAAEGGPAFDAALSALSQSWGEPAGLMAGGGSIPL
                     VMALDTAVPTAEKLLFGATDGYANIHGPNERVLLDELEKAVVAKALFFQEYAHTFEGKK
                     "
     gene            27492..28127
                     /locus_tag="AOT96_RS11200"
                     /old_locus_tag="AOT96_11200"
     CDS             27492..28127
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007735928.1"
                     /locus_tag="AOT96_RS11200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11200"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_065351746.1"
                     /transl_table=11
                     /translation="MTVTTSETQERARTARKLGDGPRRAGLLSTAALCFGELGYDAVTV
                     ETITTRADVSRATFYAYFSSKDEVFRAVAEMMCRRFLDAQHMEGPAAEDLREVLRTTTS
                     AFITAVYTYGDLLAVIEHRARVDSEVERSWSAVREKLVSRYVRFVERIRRVHDVDPCVS
                     PPVLVQMISDAQMAGGARLSKASVEEQNQFIADMTTMSERLIGFEESK"
     misc_feature    complement(28129..28142)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.14"
                     /tool="antismash"
     gene            28153..29850
                     /locus_tag="AOT96_RS11205"
                     /old_locus_tag="AOT96_11205"
     CDS             28153..29850
                     /NRPS_PKS="Domain: AMP-binding (43-468). E-value: 4.8e-93.
                     Score: 303.9. Matches aSDomain:
                     nrpspksdomains_AOT96_RS11205_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003944167.1"
                     /locus_tag="AOT96_RS11205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_11205"
                     /product="AMP-binding protein"
                     /protein_id="WP_065351747.1"
                     /sec_met_domain="AMP-binding (E-value: 4.7e-97, bitscore:
                     323.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEQDVLEAALAEISALQQAHWPAGIPRAVEYPLEGGGLVDYLRH
                     WAVERPDTPAIVFYGRVITYSEYDELSDRFAGWLLSLGVERGDRVGVHLVNCPQFHIAM
                     LGILKVGAVHVPINPLFREHELIHELNDAGVKVLLTQNTFSKLVKKVRSQTPLEHVAKT
                     AVSDMLTAIPTVELPFEVDDPRLSDWQSIITSERATPVATELDSLAALNYTGGTTGMPK
                     GCEHTQRHMVYTAATATLAGGAQVGTNPPVSLVFLPIFWIAGEDFGILVPLVNGGTVVL
                     LNRWDAETTLDAVEAYGVTSLVGTVDNYVELMDTPGFAERNLSTLQNVMAVSFVLKLDP
                     ATRQRWREATGGVLREASYGMTETHTADTITLGFQDGDYDLKSEPVFCGIPVPGTDVLI
                     VDHDGRPVPVGEHGQIIVRSPSILSAYYRNEAATADAIRDGWLQTGDVGKFSERGGLHY
                     LARNKEMIKTNGMSVFPSEVEALLMLHPAIEKAAVVPKPDPDKGQVAFAFVQMVEGSDT
                     VADEIVSWAKENMATYKVPEVEVLEALPMTATGKVRKGDLFERTQGDK"
     aSDomain        28282..29556
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AOT96_RS11205_AMP-binding.1"
                     /evalue="4.80E-93"
                     /label="AOT96_RS11205_AMP-binding.1"
                     /locus_tag="AOT96_RS11205"
                     /protein_end="468"
                     /protein_start="43"
                     /score="303.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RHWAVERPDTPAIVFYGRVITYSEYDELSDRFAGWLLSLGVERGD
                     RVGVHLVNCPQFHIAMLGILKVGAVHVPINPLFREHELIHELNDAGVKVLLTQNTFSKL
                     VKKVRSQTPLEHVAKTAVSDMLTAIPTVELPFEVDDPRLSDWQSIITSERATPVATELD
                     SLAALNYTGGTTGMPKGCEHTQRHMVYTAATATLAGGAQVGTNPPVSLVFLPIFWIAGE
                     DFGILVPLVNGGTVVLLNRWDAETTLDAVEAYGVTSLVGTVDNYVELMDTPGFAERNLS
                     TLQNVMAVSFVLKLDPATRQRWREATGGVLREASYGMTETHTADTITLGFQDGDYDLKS
                     EPVFCGIPVPGTDVLIVDHDGRPVPVGEHGQIIVRSPSILSAYYRNEAATADAIRDGWL
                     QTGDVGKFSERGGLHYLARNKEMIKT"
     CDS_motif       28465..28503
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AOT96_RS11205_0001"
                     /evalue="5.20E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="AOT96_RS11205"
                     /protein_end="117"
                     /protein_start="104"
                     /score="10.5"
                     /tool="antismash"
                     /translation="LGILKVGAVHVPI"
     CDS_motif       28783..28830
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AOT96_RS11205_0002"
                     /evalue="2.10E-03"
                     /label="NRPS-A_a3"
                     /locus_tag="AOT96_RS11205"
                     /protein_end="226"
                     /protein_start="210"
                     /score="11.2"
                     /tool="antismash"
                     /translation="LNYTGGTTGMPKGCEH"
ORIGIN
        1 aggaaggacg gttcggcatg cgcttggctt ttgtcggtgt cggtccccaa atcgagctga
       61 tcgaactcct cgaaggcccc agctcgtacc acgaatggca ttcgagtcac ggtttcggat
      121 tgcaccatct gggttttgtc gtcccgtcga tcaaggacgc gatgatcgaa atggcggaac
      181 acgacctcga tttgattcag tcggggtacg gctatggggc gaacggggac ggaggttttg
      241 cgtactacga cactcaggat tcggtcggcg cgattgtcga gctcatcgag gttccatcga
      301 tccgacgacc atccgaggtt ctgtagaagc cgcgtcgatc agcgcggtgt agacacgctc
      361 cggctcttcg gcgatgcgat tgagtacgta cagccaccac tgtgttccga agatgacgta
      421 ttcgcgtgtg gtgaagcccg ctcctcggag tgcgtccagt tgctcggtac cgaggccgag
      481 cagcatctcg aactcgacgt gctcgcctct gagcttcgaa tcatgctcgg cgcgtagtgc
      541 ttcgaggatg tcgcggtcat gtgtcgcgat ggagacctgg tgacccgatt cgacgattcg
      601 ggctgcgtag tcgagatacg cgctgcgcag ttcggcacta ccgcgtgggt aggcgacgga
      661 ctcggcttcg aggaaggcgc ccttcacgag acggatgcgg ccgggtcggt ccagcagagc
      721 ggcgagatcc tttgccgtgc ggtgcagtcg ggcctgaacg gtgatcccca cgtgagtgaa
      781 gcgctcggcc agtcgcgcgt gcatgtcgag gaccaggtcg gtgcggtcgg acgcttcggc
      841 ggagatgatc agctcggcac cggcgcgttc cgtggcctcg gccaggcgca cgacattgcg
      901 aaagcactgc tccggatcga tcaccaagcc gatgtgcgag aggtcgaacg acacggtgct
      961 ctcgacaccc gacgtgccga ttcgttccgc gagttccacg aaaacatcgg tttcggcgtt
     1021 cgcgagctcg ggatcccgga cgctttcccc ggtgtattcg atgctcgcct tgtgtcctcg
     1081 cgcgaagatc gaggggaggc ggtcgaaagc gtcgtcgatg gtttcgccgc cgatgtagcg
     1141 agcggcgact ttccgtgcga gtgctgcagt cgcagcgtcc gccatggtgc gttctttcag
     1201 ggattcgtcg agtgcgaggc ggcgtaggac gtctgcggcc tgggcttgta gatccgtgtt
     1261 cacggcttca gcgtatccgg acgagggtgc gggaattatt ctccagaccc ttgcgttcga
     1321 tctattgtcg atatatcgtc gatacgtcaa acaaacacag acagtccagg aggacaacat
     1381 gtacgcccca cacaacaacc cagaaatgca agaacgtcgc gagcatggcc gccgaggccc
     1441 gcatcgtgga cacggtttcc gtcgaggatt cgagggcgag cgccccgagg gtcgcttcga
     1501 agaccgagca gaaggacgcc ccgaaggccg acgcggtcgc gaaggtcagc gcgaatttgg
     1561 tcgtcctgac cagcgcggat ttggtcgtcc cgaccagcgt ggacacggtc ggccgggctt
     1621 tggtgaagcc ggcgcagcgc tccgtcccgc gatgggtcta ctccgaggtg ccgctgttgc
     1681 ggtagccgca ggtgggaccg ctgagcaggt cgccaaggca gaggcaattc ttgccgaggc
     1741 gcgccgtgca ctgttcgaga tgctggcgga aaagccggct gacgtgcagc aggctcacgc
     1801 agaatctacc gacacactgc cggcagagtg atcacggcgc tcaggcgccg acggtgactt
     1861 cctcgctgtt catgccggaa acgtggccgt cggcgccctc tcgccagtac ccgacaacat
     1921 tgtgcttgtc gcgagcaatt cctcgaactt ccctcaggtg cttgcgaata cgacggctgg
     1981 ttgcgctttc gcacgccacc cacgcgtaga cgtcggccgt ttcggattcg ggaaactcga
     2041 ccttctccac agcttcgaac agcgcgctcg gcgcctttcc gaggccactc cccacgagcc
     2101 acgtgtacgt gacgtcgccg cgagtgacaa attcctgtcg atcctcttcg gtttcgacct
     2161 cgatgatcgc ctgtgcgaca tcgccttcac gaagttcttc gacaatcctg cccagtccgg
     2221 ggagacccgt ggcgtctgcg accagcagct gccagcgagg acccgccggt gcttggtagt
     2281 gggaccgcga actgtccgac cagaagacgc ctagtaggtg acctggttcg gcccgcaggg
     2341 cccaatccgc tgcaataccg ccagggtgca cgacgaagtc gatttccaga cgtcggccgc
     2401 cgtcgtgcac cttgcgcacg gtgtagtgcc gccacggtgg ctcggttccg agatcggcct
     2461 tgccgtagtc gggattgttg aagtagtcgt attctgcttc tgtttcaccg ggtttcggga
     2521 acgcgaggtc gatgcgctcg tcgccttgtc cgccggtcgg ccagtgccag tcgccttctg
     2581 cctcgatgct gattcgccgc atgtgcgggg tcagggacgt gacggtgaca acgcgggcgg
     2641 gttcgcagaa agacatgcct cgaccctatg ggtccggcgt gtcgaagtgg agacagatgc
     2701 tgtcgcaaga cggacatcga gcgcagccga aaaggccagc gtatgccccg gggcatgatt
     2761 cttccctggt gtacacgctg gccttttcag ttatgtcggt tcacgccgct gtcggtgggc
     2821 tgttcccacc gatcggctgt tgatacggat cgatcgacat cggtggatag aacaccgatt
     2881 tccgatccgg cccgatctcc acccgccact ccgtgtggtg cagcgtccgg tggtgatgac
     2941 cgcacaacaa gatcagattg tcgagatctg ttgggccgcc atcgttccag tgaacaatat
     3001 gatgggcatc gcaccacccc gacggcgttc cgcaccccgg aaacgcgcac ccaccatcac
     3061 gaaccgccaa cgcccgccgt tggggtaccg tcgcggtcct tgcttctttg ccgcagtcga
     3121 gcggaacccc gttctcatcc aacaaaatcc gcgtcacggt gcagtcgcag gccaacatcc
     3181 gtgcggtgtc gatgctgatc gggcccaccc aatccgccca cgcgaacccg agttcctccg
     3241 tcgacggcag gaggtctttc aaagcctgca gatccgtcat gtctttcgcg gacgcggtga
     3301 ccgtgatgtg cggtttcacc ccgccttcga tcggacccaa ccccgcccgc tcgtaccgcc
     3361 gcagtagttc gcagaacccg tccgcccgcc gtagcgccgg cgtacgggtg tccttgacgc
     3421 cgtccttctc cggcgtcggc gcagacagac tcgacaacaa cgtgatcaga cgcgccccgt
     3481 tcaccgcatc cagatcaccc ttcaccgaca cacgcccgta caaacctttc gaggcataga
     3541 actcgttgcg ctccgaatcc tcacccaccg gaacaccgtc ttcgcgtttg ccgtactgct
     3601 tctcgatccg ccggatcgcc gcccgcaccg catcacaatc agcgatgttc ttcgacgcca
     3661 accccaacag aatcccgcga gccttgtcca catctgccag ggtcatgttc ttgggtggat
     3721 gctgacaaaa cgacgccacc tgacgggctt tcaacgcatc cacatcaccg cggtgaaacg
     3781 catccgccac aacaggttcg agcatcaaca accgcgccaa cccgaccagc agactgcact
     3841 caccgatctc caaattcgtc gacccgtgca accactgcgc gatcgcccga aaacccttcc
     3901 caccgagaac gtcccgggaa aacatctcca cgatcagcaa caccatccgc gactgcaact
     3961 cgtgccggac acgcaccaga tcgagaacct cactcttgag gtcctcgcca tccagttgcc
     4021 acgcttcccg actgtccatg ctaaaagtct aatcgaacaa agtttcgaac acaagagaat
     4081 cgcaggcgaa aattgctgct gtccagctac tttcgacaat tcgggcaaat gtcagattga
     4141 acccaactcg cgcgcacgag ctaccgccga cgtccgcgac ttcactccca acttgccgaa
     4201 gatgtgaacc aggtgcgact tgaccgtggt ctcactcagg aacagttctt tgccgatctc
     4261 tcggttggag cgacccgccg ccaccaactt cagaacttcg atttcccttg ggctgaggct
     4321 ggtttcgggt ttgcgtaccc gagtcatgag cttcgacgcg atggcggggg agagaacgct
     4381 gtccccgctc gcagcggcgc ggacggctga cagcaactcg accggtggtg tgtccttgag
     4441 taggtacccg ctggccccgg cctcgacagc gctcaagatg tctgcatccg tgtcgtagtt
     4501 ggtcacgacg agtacgtgcg gcggattcgg cagcgcgcac accgcgcggg tggcgtcgac
     4561 gcccgtcttc ccggggccga atcgcaggtc catgagcacg aggtcgaccg gcgtggtggc
     4621 gcagaaggct atggcttcct cggcggtgcc cgcttcgccg actacctcga tgtcggcttc
     4681 gctttcgagc agcgctcgta gcccggcgcg cacgatcgcg tgatcgtcgg cgagcagcag
     4741 gcggatcacg gttcgccgac ttcgagagga aacgtcactg cgacggccgt gtgtcccggc
     4801 tcggactcga tggagaaagt cccgccctgc agttcgacgc gccggcgaat tgcattgagg
     4861 ccgaaagatt ccgccgggcc acgttcgaga actgccacgt cgaaaccgtg accgttgtcg
     4921 accacgtcga ggctgacggt gtcatcggaa taggtcagtg tcacagccat tctggttgca
     4981 tcggcatggc ggagaacatt ggacaccgcg ccctgagcga tgcgtaccaa tgttgcttcg
     5041 aggggcatcg gcagccgcac tgcctcgcct tcgaccacgg agcgcgcttc cagttcagga
     5101 ctgctcgcgc gttcgcagat tcgacgaagc gcgtcggcga gcgactgacc gtccaaggcc
     5161 gcgggcgtca attcggctat gagttggcgg gtttcggcaa gactgtccgc ggcagtttcc
     5221 cgtgcgaggc tgatctgacg gatggccggg ctgtccggat cggcgcgttc ggcagcgtga
     5281 aggagcatct ggatgctcga aagtccctgg gccacggtgt cgtgaatctc ggcggcgagt
     5341 ctttcacgtt ccgcgaattt tccggcgtcg cgagacgtcg acgccaattc ttcacgagta
     5401 ttcatcaact cgtcgatgag acgaccgcgc tcggctgcct cgcggtacag cgcttgatat
     5461 ccgaggccga ttgcaaccgc tacggcagcg ccgatgatcg ggccgacggc gccggcaatc
     5521 gtccatccac gatgcaggcc ggtgccgacc acggcgacag ccgttgccgc ggtgacggcg
     5581 agaagactcc aggggcgtcg cagaatatgg agatagagga agaagagtcc gaacgcgagg
     5641 taggcggcgt cggcggatac cgccatcgtc gcgatccaga cgagggtcag cacggccagc
     5701 caccagcggg cagcgttgcc gcgcagcctt ttggcgaccc cgaaaagata gacggcaaca
     5761 aagatcacgg ccaacgcgat gattgttgcg gtcaggtcgg attcgtcgag cagcgctcga
     5821 agaaacacca caccggccag cgccatgaca aggacatgca ggcccagttg taggccggcg
     5881 aagacaggcg tgagcggaga tcggtgcatc tcgcccagct tagcgaggtt cgggcctcgt
     5941 tcatccatca aaagttgtaa accgggatgg ttctttcgag cgctggaatg tcgatccgag
     6001 gtgcgatgga aagagtctgc atccgcgaga gcgtagaggc aagcacagga aaggaattca
     6061 cagtgtttgt cgcaatgagg gacttacggg cagcgcgagg tcgtttcgcg ctgatctccg
     6121 tcgtggttct gttggttgca cttctggtca gttttctcag cgggttgact gcaggacttc
     6181 gccatcagaa cgtgtcagcc atcgaggcca tgaatgccga cacggtggtg ttcgccgaca
     6241 ccggagccgg ggcgtcgttc gacgagtcgg cgctcacgca ggaccaggtc aacgcttgga
     6301 cctccacgtc gaaggacgtc gatcccatcg gaatcggtcg cgggaaagcg ggattggccg
     6361 acggaaatca gaagtcggtg gccctgttcg gcgctgatgg cggtttcggt gacgtgacgc
     6421 cgtcggcgtc aggcacggtg gtgttgagcg aaggtgccgc tcgcgatctg ggggcgggcg
     6481 ccggcgatca ggtgagtgtc ggtacgcagc agttcaccgt cagcgccgtt cgcggtgacg
     6541 actggtacag ccattcgccc gtcgtctgga tgacgctcga cgactggcag gcggccaatc
     6601 cgcgcggcgg agttgcgaca gtactggctg tcaccggagc ctctgacgct tccgcaacgg
     6661 acaaggcggc tgcgacgacg tcgacgacgg tcagcggttc gctcgacgcg atcggttcgt
     6721 acaagtcgga gaacgggtcg ttgacgttga tgacgctcat gttgttcgcg atctcagccc
     6781 tggtgatcgg tgcgttcttc acggtgtgga cgatccagcg aactccggac atcgcgacgc
     6841 tgaaagcgct cggtgcgact accggttcgc tggtgcgcga cgcactgggt caggcgctca
     6901 tcgttctgat tgccggtgtc accgtcggaa tcgggctgac ggccgtggcc ggatcgctga
     6961 tcggtgacgc catgccgttt gtcctggacg catccaccac cgtcgtacct gccgtggcat
     7021 tgatcgggct cggtctgctc ggcgcggcct ttgcacttcg attcctctcg accaccgatc
     7081 cactcacagc attggggagc gcacgatgac catgacaacc ggcaccacag ttctcgacat
     7141 ccagaacgtc gatctgacgt ttcccgatgg gcaatcgcgg gtgacggcgc tggacgacgt
     7201 gtctctgcga ctgcaccgcg gcgagatcgc cgcgatcacc gggccctcgg gttcgggcaa
     7261 gtccagcctg ttggcggtgg cgtcgacgct gatccgtccg gattccgggc acgtctatct
     7321 ccggacgccg gaaggcagca ccgacatcgc tgcgctgagt cggcgggcgg cgtcggagct
     7381 gcgacgctcg tcgatcggca tcgtcttcca acagtcgaac ctcgtgtctt cgctgactgc
     7441 actggagcag ctcgaggtga tggcgcatct ggggcagtcc gtgttcacgt cacgggcccg
     7501 tcgcaaggcc gtgaaatcaa aagcgatgga tttgctggac gctgtcgggc tcgcggatca
     7561 gagcggaaaa cggccgtccc agctgtcggg agggcagcga cagcgcgtca atctcgcgcg
     7621 agcattgatg aacgatccgc agcttctcgt ggtcgacgag cccacgagtg cgctcgatca
     7681 ggagcgcggt gccgctgtca tggatctgat catcggggtg gtgcgggaac gcgaggcggc
     7741 aacccttctc gtgacacacg accgaagtca cctgtctcgg atggatactg tctatcgtgt
     7801 tgttgacggt tccttggcgg aggatcagga ggcgctcgcg gcgtgactca ggcgggcacg
     7861 attcgggcat tcgtcactgc atccgggcgg gaagtcaacc cgcgatttgc tgggcagtta
     7921 gactgttgtc gactcgggca acttgagagg acgtgttatg gaacgccgcc gcaacgttgc
     7981 gcagccgcca caatcgccga ttgcggatct ggagcagatg cctgccctga ttctcctcga
     8041 caggcttccg gtgccggtca tggccgttca ccgcgatggc agcatcgttt ttgccaaccc
     8101 gtctttcgct gacatgctgg gatatcccaa gaaggccgtc tcggcgttgc gtttgcagga
     8161 catcctctac gacaaggatg ccgacgacgt cagtgcagag caggcccatc gtgaactgag
     8221 ttccgagccg ggctcggtca aggagttcgt gcactccgac tccacgttgg tgcgcgcgac
     8281 ggtcagccag tctctgctcc gacgggacga cgacacgatc acccttgccg tcctccacga
     8341 tctgacggag cgcctgtgga acaacccacg gcacatcgac gacaagccca ccaagtaatc
     8401 ccagctactt ccgggatttg acggttcggt ccaggccgag ggtggcggca agggtgttga
     8461 ccacccattc ttcgtactgt tggccggtcc aacccgcgcc gaccacgagg tctgtatagg
     8521 tctcgggact gagcagcgtg agtgcgacgt tcacagctgt ttcgaggtcg acggttggcg
     8581 ctttttcgac gatgccgacc atcagatgtt cctgcacagt gcgtcgctga gtgcggttga
     8641 tttgccacag acgggcggcg tcctcgtcgg cggaagcggc ggcccgcagt gccagcagga
     8701 tgtctgcggt gcgttccaga atgagccgtc cgtggtgaac ctgaatccgg agttgcccga
     8761 gtggatgtgg ggcgccgagt gctgccgcca cccacggacg gtcgagagtt gccgtctttt
     8821 cctcgtcgcc cgcaacggcc acgtcgagca gtgctgacag cacgctcggc ttgttgccga
     8881 acacgaaata gacactctgc accgacacgc ccgccgccgc ggcaagctgc ttgatcgtgg
     8941 cggccgcgta gccgggatcg acaaaaacct cacgcgctgc ctcgatgatc ttgcgccgcg
     9001 ccgacatgtc ttcccgaaga acctcagtca tgattagagt ctaactctag agtcgaactc
     9061 tagcgactcg ggaggcgaag taatgacgaa ggttcttgta ctcggtggct acggtgccgt
     9121 cgggattccc ctgatgaaac aactcgcgaa ggtccccgaa atctccgcgt actccgccgg
     9181 ccgtgaccct gcccgcgcgg acgtcgtcgt tgatcttaaa gaaccaggcg cgtattcgac
     9241 tgtggttcga gacttcgatg tcgtggtgaa tgcctcgggt ttcgaggatg ttcgcctggc
     9301 cgacgaagcg gtacgcggtg gggcggcatt cgtcgacgtc acggcgacct cgaactactg
     9361 cgaagaactg gaagcggtcg acggacccgt cctgatgggc gtcggattgg cgccgggatt
     9421 gaccagtgtc cttgccgccg aggcgcatcg actcggcggg ggacccgtgg acatcgtgat
     9481 cggcctcggc ggcggagaac tacacggacc ggccgcgacg gcgtggacgt acggaatgtt
     9541 gggcacgagg tttcctgatc ccgacggacg atcgattcgc aactacaccg ggatgaagac
     9601 gtttcgaata ccggccgatg cgaccggcta ccgcaccggt cctgctgtgc gggccgattt
     9661 ttcggaccag catgcgttga cgcgagacct cggtgttccg gtcaggacgt acctgcgatt
     9721 ggacacgtcc accgcgacgc tcggacttgc ggccatgacg tgggcacccg cgctacagaa
     9781 ggtcgtgccg aagaagctgt ggggctcgga tcgttgggta gcgatggccc gagcggatac
     9841 cggcccggcg ctgtgggttt cggggcgtag ccagtcggtc gcgacggcag ctatcgccgc
     9901 gcgcgccgtg caggtgattc gggatgccgc gatctcgaag ccgacgtggt tccacgcggt
     9961 ggaaaccacc gagtcgttgc aagcggcggt tcccgaactg tcagtgcggc aatgggatgg
    10021 tgcgagccga tcgtccggca agactgtcca ctagtcgggg cgagccgaga aacggcaatc
    10081 cggcggccgc attggtgaga caaccgggta cgacgacgcg gacgacgtgc aggccggcgt
    10141 ggagaacatc agttgtggtg agatcgaccc atgccggccg gaaaccggct gccgtcagag
    10201 cgctttcggt gccggcggct gatgtcagag agtcgagtcc cacctcgccg acgacggcac
    10261 cgaccagctc actctcgaat cgtgcttgga tctccgggtc caggtgaagt tgcaagtggc
    10321 atccgtagtc catcacgtcg gcaaaatccg atcggtaggc gcctgcatag cttcggtcag
    10381 ctcgccaatg cgcaagcgga ctggtcgggg aggccgcggc tcgaccgatg ccgctctgcg
    10441 ggttgtcgta gtcggcggaa agcagctgca gctgaagcgc ttcgccgagt gacttgaacg
    10501 cagcggtctg ggcgtcttcg tggcaggcgg taccgatggt cgagtatccg gtgagtccgt
    10561 cgtggatgag ggcgccgagc accgggatcc cgaaatcgct gtcgaatgac aaccacctgg
    10621 tcgagagggt gccgtgattc cccagtcgcc gaagcacctc gggaatgccg gtgacgaccc
    10681 gaacaccacg ccgcccggtc caggacagcg tcatcgcgtc tcgttcgact atctcgcgca
    10741 aggcattgtc gattgcgaac ttcaccgagg gtccggcggc gagacccgcc tgagctaccg
    10801 gagagatcgc cggacccgtc cgggcgacga aatgaggata cgaaccccag acgagttcgg
    10861 ccggtaccca gatatccgaa cccgtgatca ggtcggctcc gcgagtccag tccatctcca
    10921 gatcgtcggt tggttcgacg aacgggaact gtggccgcgc gcactgggcg gcgtcgaaac
    10981 gcgcgagttg tgacaggtcg atgcttgctc cgatcaaggc atcggccgac ccgcggacga
    11041 tcggtttggc gacgatgttg ccgcaatatc gttccaccgc ttcgcctatc gcagctgcgg
    11101 taggccgcgc acggtcaccc agatcgaagc aatatccggc gccggccgag tcactggacc
    11161 agggtgaaaa gcgtgctgaa tcactgacat acgagtgaat cagcttgaac tcgggcggaa
    11221 agtgctgggg aacaacggcg tcgaccagct ctcgaatgat cccagttcgg cggtcgacga
    11281 gcgaagatgt catgcgaggg ggaccggcag atgcagatgg gtggtcgatg cgctggtcaa
    11341 tctgctacct ccaagaaggg gaaaggctgc cggggcgttg ttgtacaggc ccggagtcag
    11401 gatgcggacg acgtgcaacc cggcaatcga gatgtcgccg gtggtgagat cgacggaaat
    11461 cggctggtgt ccccgtgaca tcagaagcgc tacgagagaa gccagatcca acggcgcttc
    11521 gtcgggaatc tctgataccg agagtgtttc ggtgtagtcg aagagatgtt cctctgcggc
    11581 cagggccatc acgggatcga gataaagttg ggcgacggtc ggcagatcga cgatgtcttt
    11641 ccattgcgga tcgaactcgt cccggtaacg acggtcggcc cgaaagggtt tgtacaggtg
    11701 cgccggcagc gttccgtccg ccacgctgcg ccaggtcggc ccgtcggggt cggcgaggtc
    11761 gatcgtgatg gcaagtacgg catacgcctc gacaagcgcc ttcgagactg ccgcctccac
    11821 cgtcggtcga caagctgtgc ccagcgcgac cagtccacgt cggtcatcgc ggatccacgc
    11881 tgcggcgacg ggaatgccga agggggaggg aagcagcagc actcgaacgc tccgggtctg
    11941 gctctccaga tccccgagtt ggcggtgcgc aggcaaccgc tcccagtcgg aaagctcgat
    12001 cgccggctgt gaccggtccc cgcaccacca cagcgcggtg gcatcgcgtt cgagaagttc
    12061 cagcagagct gacatctcgg cctcgtcgcg tgagcgtccc gctgcgattc cggcgtactg
    12121 caacgacgcg atcggtggct cgcagcgacg ggtgcctgtg tagtacccga gataagtcag
    12181 ggccgcaggc acgtaggtgg gcaccttttc gtccatggtg tgacccaatg cccagcgaat
    12241 gttcagatca gaggtgaagg gaacaaaggg gaatccggga aggcggtact gatcctcgct
    12301 gtacaacgca aattcagcgg gatcgacgac ccgtgagccg gccagttcca gcgctgatgc
    12361 actgctgcgg accagatctt cggggaccac gttgccgcaa tatctttcga cggcctcacc
    12421 ggtcgccgcc ccgcgagctg ctgcatcgtc gcgtatcgaa gccccgaatc cgtaagggtc
    12481 cgcgcgaaac agtgaaccgc tgccgccgaa gtttctggtg tcggccaccc tcgcggccca
    12541 accgacccag cctgtcggca tgtccgagcg aatgtgtggt tccagtgagg tcagcacgcc
    12601 gctccgggcg tcgaccagca agtcatccac cggcagttcc tccgagtatc ggcagggtca
    12661 acgacccgga aaatgattgg tgcagtgcgg tactgcgtgt tcctcgatag cgatcaccgt
    12721 ctccgagatt gcgtgcgagt cgtgggaagt ccgagccggc gatccgcagc gtcaagacat
    12781 cacccgcgcg cacagtgtgc aacacgggat ccagatcgat tgtcaccatc gtcggctgca
    12841 cgctgacgcc cgcgccccgt gcgatcgacc tggtgactcc agcggcatct acgacgctca
    12901 gctcgacgat ccaatcggct tcgccctcgg gcgagtgcac tttcagctcc accgatggtg
    12961 ttccggagag tacggagtcg tgcttgatat cgaaagtcca gaaaacacag tcgtttcggg
    13021 cccttgaggc gtcatacagg aaggtgtaga ccgcatcctt ccgatctggt tcgagacgaa
    13081 cgcgattcgc acccgtgaca tacggttcgc tcgaccaatc gcctgcaccc cggtcgaata
    13141 cccgattgat ggtcacgggc cgcgccgaga atatcgattc catccactcg acctgaaggc
    13201 ggccgaaact tgtctcgccg accattccag ggcggaggtc gtgcgcccag gggcccacga
    13261 tcaaactctg cggcccgcgc ccaacggacg tgaagtgccg cagtgtctcc cgaatcatcg
    13321 catcgtccca accgccgatg tgcagcccgg cgatgtcgag ttcggagagt tcgtccgcgg
    13381 acaccagatc atcgccaccg aagtcttcgc gtttacgagc gcgaaggatc gccgtcaacc
    13441 agcccggtga atcggaggtc agaccaacct cctcgatcat cgactgcacc gggagatgtt
    13501 ccagcaaaga cgaatccgag cgcatcaggg cagggatgaa accctcacga gaggaagacg
    13561 aatctccgtg ctcgccccac cacgccagat gctcggcgag gagaagtatc cccgagggat
    13621 cacgtttgac gcggtcgctt ccgatggtcg gcaccttgga gacgacgccg tctacacgaa
    13681 atgaccgatc ggcgctgttg gtctcggcag caaatgccca ggcggttccg gccgcatacg
    13741 aagccccgct tgcgatgacg cactccggtg tccacggctg atcctgcagc cactcggcca
    13801 gggcggcgct gtcctcgcgc tcgtggacgt agggttccca agatccggtg gaatcgtgcc
    13861 gtccgcgtac gtcctgcgag atgaatgcaa ttcctcgcaa tcgccattcg atcccctccg
    13921 ccagatgcca tccacgcccg tacggggtgc ggatcacgat cagtccccgc ggtgaagaat
    13981 ccggtgggag aagcacatcc gtagccaacg aagaaccgtc tgctgccggg atcttcacgc
    14041 cgagtgagat caccggagcg tcggcgcggg ttcgagaacg ccgccgggca gtggtagcac
    14101 gggatggcga gtcatcatga gggttcgcgg attcatccgg atctggtggt gaaggtgtga
    14161 tggcggtgcg ccatgtacac cagccacgac gtccgaacat gcaagcgcac tggccattgc
    14221 ggctgcggtg ggttcaagtt cgagcgggcg aggttcgctg ccggcgaggt gattccacag
    14281 tgcctgcaga tgatccggga cgcgcgacgc ggcaagccgt cgaccgcaga cgtcccggta
    14341 gcttgcgctg ccgataccgt cgaagaaggg tccgatgcag atctcaccca gctccgcgtg
    14401 gacggtttgc cacggtgttt ggtttcggcg gcaccaggta tcgagttccg accactcgtc
    14461 gtgaggagga gccccggcaa ccgacagtac gaggtccgac gacgcaacgt cgtcttcgat
    14521 tggcgcagta gtggatacga cctcgagatg cggaagagcc ttggagagca gggcgatgca
    14581 agcatcggca acgggcccga tcccgtccat cagcacacgc tgtgggcgcg gaatctccgg
    14641 cgcttgaccc ggaacaacca gcacgccgcg agagacgagg gcgtcggcga tctcgatagc
    14701 tcccgggccg agcaccgaac cagagcgcct gagaaagttg tcgagttccg cgaggtcttc
    14761 ggccggcgcg ccgatcgtga ccgcgttctc gtccggtgtc aggtaatgcc aagtgccgtc
    14821 cggggtcgga tacagctggt gtccgtcggc gagggcgtac acggatctcc ttgtcggtgc
    14881 ccgcacccga cgagtcggat gcgggcgggg tcatcggcag atcagactgt cgaaacagtc
    14941 tggatcaggg gaggtttcag ctctggaagc tgaacgggtt gtcgacgagg gcgttggtgc
    15001 ccacaccctg cagggcgtgt gcggacgttg cctcggcaac cggctcgaag gtgaacgggt
    15061 tgtcgacgag agcgttggtg ccgacgccct ggagtgcatt ggccggagcc gagttggaga
    15121 cgctgtcgaa cgaaatgttg ctcattgtca tcccttccgt aatggaaacc atttccatta
    15181 cgatgccacc gtacgaaaga tcgccacgga gagcaacagg tacaagagag tgcatacatg
    15241 agcgagaccc cgacgacggg atccgtcgaa gcgcaaccac atgtctttcg ggacagatcg
    15301 tttcgattgt tcttcacggc tcgtacgatt gccgtagccg gtgcggcggt caccggagtg
    15361 gccatgccga tcctggtgtt cgacatcagc cggtctccgt ttctcacctc gctcgcggct
    15421 gcggggacgg ttctgccgta tctcgtgttc ggcttgttcg ccggcgccgt ggcagaccga
    15481 gtcaaccggc ggacggtcat cctgtgtgcg caggccgttg ctgcacttgc tttggcgagt
    15541 attccggcag cgcaggcact aggcgtattg acggcgtggc atgcggtcgg cgtatcgatg
    15601 tgcatcggaa cgtgtttcgt gtggttcgac gccgctgctt tcggagcgct gcctgctctg
    15661 gtcggtcggc agaggatacc ggcggccaac agcgcgctgt ggacgtccag cacgctgatc
    15721 gatgttgtct ttccagcgat agccggcgtg cttgtggcct cgatcggccc ggcctacgca
    15781 ttgggtgctg atgcactggc ttacgtactg gccgggctgg ccatggcctc gatcggagcc
    15841 tcgttttcga ttactcctgc ggcgccgaag aagtcgggaa ccggaattgc gcgtgacata
    15901 cgcgagggcc tcagcttcct ctggcggtcg ccgcttctgc gagccttgac cggcgtcggc
    15961 ttcgtcaatt ccctgacgca gggtgcggtt acggcgctcc tggtggtgta cgcatccgag
    16021 aggcttggga tttcgacgtc gagtccgatg atcggcgccg tgtggacggc cgtctccgtg
    16081 ggtggagtgg tcggggcgct cgtgcttcca cgcctaccgg cgcagtggcc ggtcggggcg
    16141 atcactgtcg gggcgctgac catcgccccg gtggtgctgt tcgtcgttgc gacaaccggc
    16201 aacgccggcg ccgcgatcac ggcgctcgtc gtctactccg gctgtgcgac cgtcaccatc
    16261 ctcaatggca tcggtgcacg tcagcgcctg actccggatc gtctgcaggg gcgcgtgaac
    16321 accacggcga ggatggtcgc ctggggtggt tcgccggtcg gcgccttgat tgccggggca
    16381 atcgcaggac gctgggacat cggcaccgcc tacctcgttg cgtgcatctt tgcgctggtc
    16441 ggggcgctct tcgcgtgggc gagcgcgctg cggaccgacc cttatccgca caaatgagca
    16501 tgtgactatt aatgaaaacg actgtcgtta tggttagatc cacctgttca tgactgcgaa
    16561 ccccaccgac tcaggagtgc gatgacgctg accagcgagg cagcaccacg agtgccgtcg
    16621 cgtccacatc ccgtcggcga gcgcgggtac gtcccgtttc tgttggccac ggcggttgtg
    16681 cttgtcgcgg tctccaccgt cgcggtgtgg tcgggtgccg cgtcggtgtc ctttgccgac
    16741 gtgttcgcgg tgttgtacgc acacgtcggc ggtccgccgg tcgacccgtt gctcgatcgg
    16801 atcgtgtggg gattgcgggt accgcgcatt ctgattgcgg cattggcggg cgccggattg
    16861 tcgttggccg gcgccgtgct gcaagcgttg gtgcgcaacc cgattgccga tccgtacatt
    16921 ctgggcgtgg gttccggagc atccttcggt gcagtactga tcatgacgac cggcatcgga
    16981 accagcctgt cgatcggtgt tccggtggca gccttcctgg gggccatggt ctccctgatc
    17041 gcggttctcg tactgggtcg gcgagaggga atgctcgtcc cgctgcgcat ggtcctggcc
    17101 ggagttgcca tcggctatct gctctcggct gcaacaagtt ttgtgcagtt gcgcgccgat
    17161 ccgagtcagc tttcgggagt gctcttctgg ttgctgggct cggtgagcgg ggccagttgg
    17221 tcggatctcg gtgtgcccgc cgcggtgatc accgtctgtg cggcaattct gttgacacaa
    17281 tcgcgccaac tcaacgcgtt ggccatggga gacgagagcg cgcaatcggt cggcgtggac
    17341 gtgcaccgta ccaggttgct actactggtg atcgcgtcgt tgctgaccgc ggttgttgta
    17401 tccgttgccg ggggaatcgg tttcgtgggg ctgctcgtgc cgcacgccgt acgacttctg
    17461 gtcggttccg atcacggcaa gctgctcccc gcgaccgcgt tggttggtgc caccttcctg
    17521 gtgatcgtcg atcttgcggc tcggatgttg gatgcgccca acgaattacc actcgggatc
    17581 atcaccgccg gattgggtgc cccgttcttt ctctggttgc ttcgacggga cggcggtgcg
    17641 cagtcatgag attgtcggcc agcggaattc acgtcgttcg gggcggacgc ctcgtggttt
    17701 cgggtgtaga cctcgaagcg cccgagggaa gcgtggtcgg actcgtcgga ccgaacggca
    17761 gtggaaagtc ctccctcctt cgcgcgttgt atcgctcgat gaagccgcga agcggaatcg
    17821 tgaaggtgga cgaggtgaat gtttgggacg atctctcgcc tcgatcggca gcacgcatca
    17881 tcggtgttgt ggggcaagag cattcatccg atttctcgtt cagcgtccgc gaggtggttg
    17941 caacgggtcg gacgccgcat cacagcgcgt tctctcgact cggtgagatc gaccgagaca
    18001 tcgtcagcgc agcactggtg cgaaccggca tgcagggctt tggatcacgt ctcttcgccg
    18061 aactgtccgg cggagaaaag cagcgtgtga tgttggcccg ggcgatcgct caacaaccgt
    18121 cggtgctggt cctggacgag cccaccaacc acctcgacat ccgcgctcaa ctcgaattga
    18181 tggaattggt cgccgaactc ggtaccacga cgattgtcgc gatccatgaa ctcgccttgg
    18241 ccgcagcgta ttgcgactac gtctgtctgc tctccggcgg ggtagttgtc gcgacaggac
    18301 caacggccga ggtcctcact gaggacctgc tgtccgaagt attcggggtt caggtgcatc
    18361 tcggcactca tccgttgacc gggcgccccc tgctctcgtt cgcccctccg ctcctacaca
    18421 cgaaagaagc agtgtcttga aatcctcgat acgtactgcc gcgctgttgt gctcggccgt
    18481 taccgccacc gcagtactga ccgcatgcgg aaactccacg gcggattcgg cggcgtcgtc
    18541 gtccgagaag atcaccgtca ccaattgtga tcgcgaggtc acggtgccca agacggcgga
    18601 gcggattgtc tcgctgtatc cgtcgatgac ggaacttctc attcagctcg gcgccgccga
    18661 ccgcattgtc ggacaatcga ataccgacct ctctcctccc agccccgaac tcgctgatca
    18721 gttcgcggcc gtgccggtac tgagcaccgg agttcccgcg aaagaagcat tgctcgacgc
    18781 ccgtccggat ctgatcgtct ccgacgggga atactggttc gacggtgacc gattgcagac
    18841 catggacgaa ttgcgtgacc tcggcatccc gatcttcgtg aacagcggct actgccacaa
    18901 ggctgtcacc gaggggcgga tcgacgacgt ctggtccgac ctcgacggtc tcggcgcctt
    18961 gaccggaact agtgacgcgg cagcaaccct cctggccgac ggcaagaagt ccctcgcagc
    19021 aaccgaggca tctgtcgccg ggcaggagcc ggttcccact gtgatggttc aggtttcgga
    19081 gggacagtcc tatgctctgg ccaggggcct ctacagcagt gtgctcgagg ccgccggggg
    19141 aagcaatctt ttcgagaacg accttcccga cggaaagtac ttcggccagg tagccacgga
    19201 atcggtgctc gcgaagtcgc cgaaggctgt cctcgtcgtc tactccaccg agtcggctcg
    19261 ggaatccacc ctggatgctg cgcggacggc atttgccgga acccccgccg cgacatcgaa
    19321 tgcgatcttt gccgttccgg aggcgtggtt cgccggcgag ttggtctcga tcgacggggc
    19381 cggcgaggtg tctcgcctgc tgcacccggg ttcgtgaccg cactcgagcg aatcgaggcc
    19441 gtcgtatcgc tgcatgcagt gttggaccgg acggtgagtc cgtcggagct accgttcgac
    19501 gagcacgcac tgccgccggt gacgtgtgaa tccgtggaac tgccggccgc gacgccactg
    19561 ccggcctgcg ggttcgcgga cgtcttgcag gcacgacgga gccgctacga ccccgcacag
    19621 acggcactcc gagcaggcga gctgtcaaac gtgttgcacc acagccttgt cagcagcccg
    19681 acggcgggcg ggatgcgcga actgacgctg tcgtttgttc tcagccgacc cggagacgag
    19741 ctcggagccg gggtataccg atatgcccga ggccgtgccg aagctgtccg gccaggcgac
    19801 gtgcgagagc accttcgagc gagcctgctc caacccgagt tcgtcgacgt gttcccggtt
    19861 cttttgtttg tggtcgccga cgtggaagcg ccgctcgaga agtacgcgat gcggcactac
    19921 cgcacgatgc acgtggatgc cggtgtgctg gttcagaatc tgtacctcat gaccgaggcg
    19981 atgggacttg cgggctgcgc catcgcagga ttcacggatg cgcgagtggc atctttgttg
    20041 aatctcgcga ctacgcagct tcccgtcatg gcttttgcac tcgggaggcg cagctaggtc
    20101 aggcgagaat acgtgccttc tgggtctcga actcggcctc ggtcaatact cccgcattct
    20161 tgagttcgcc cagcttggtg agctgttcga gcttcaagtc catcgatgct gccggagctg
    20221 cctgcggtgg caggggtggt agatcgggaa tcggcggcac cggctgggcc tgcgctgcgc
    20281 gagcctgatc ttcggcggcc caacgggtcc gctgacggcg ctgaacattg ccgtgaatgg
    20341 agcttgcgac ggctactcgg ccggctcgcc tcaagaaact catgcgtcct tctccgtatt
    20401 gcctggtgcg gtgttgtcga gtgcggtggc aagttcgtcc aagctcaggt ggccttcggt
    20461 gacaatcttt gcgccgctgc gggtccacgc gtcgatcacc ggcagtatgg ccagttcctc
    20521 gtaaacgagc acggcggcaa cactaccggt ggccaactcg tcaccaacgg cggcgatgtc
    20581 gccggcgtcg agcagtccgg aggcagcgcc gtcgaactgc gccaaatcga aatctgcgag
    20641 ttcgaaggtg gacgcgggta cgacggatac cgttccgtcg gcggctttgg tgacgaactc
    20701 gaggtcgagg atgcggatca ctccggagtc gacgagagcg agcagctgct cgaatcccgc
    20761 ggaggtcggt gcaccgccgg gaaactcgac ggcaacgtat tcgatcggac cgaattggtc
    20821 ttggttggac atcggttact tcttgccctt cgtgggttgc ggttcttcca gagcaggtac
    20881 ttcgttgggc atgcggccgg ccggaatgat ggcgagcagg gagagtccgg cgaggacgag
    20941 tagcgaggtt cgcagggcgc gcaagcgcgc ttcggtgttg atccggatgg cttcgtcgat
    21001 ctgtgcttgt gtcgccgagg tgttttcgag cgtcacgacg agttgatcgt tggggacgaa
    21061 gttgacctgg tcgagattga tcccggactc gaccttgagt gatgccggga tggtggggtt
    21121 gtcgatcagc tgcgagctga cgagggaacc gaggattccg acggcgaaga cgctggccac
    21181 cgcgatgccg acgctgccgg acatgttgtg taccagtccc cgccaggcac cgacgtcgcc
    21241 ggccagttcc ttgggggctg cggtgaggag ggtgttgaac accagcgcaa cgatggcgcc
    21301 ctgcccgagg ccgagggtga tcagtccgat gacgacaaag atctgatgcc agtcgccacg
    21361 aatggtgaag gccaacaaga tgagtccagc ggcaacgacg acgaacccgg ctcgtgcgat
    21421 cagacgcggg gagtacgtct tgtacagacg cgcgacgacg gtgctcgcga tgaagatcga
    21481 aagtgtgtac gggatgatcg agaacgacgt ctgcaagctg ctgcggccct ggatgatctg
    21541 catgtacagc ggaatgagga agttggccgc ggttcccacg aacatcatcg tcgccatgca
    21601 aatcgtggtg gcgcgctcgg cgccggtctt gaggacgtcg aggttgaaga gctgaggctt
    21661 gttctgcgcc ttgcggcttc gcgtccactg gaagaatccc tgcgcgcaga tggtgccgag
    21721 gacgatcagg atggccgcgg gtgaaacacc gatgaccgag aacggcgcag cgtcggtggc
    21781 caggatgacg ccccacgagt tcaggccgct gaaaccgaag ctgagcagga tgacggcaac
    21841 ggcagcaatg gcggcgccgg cccagtcgat ggtgatgtcc ttctgcgggg gaacaggttt
    21901 gacccggaag ctcaggatca ggttgaccac cgcgagagcc acgacgaggg cgaacgagta
    21961 tcgccacccg atcgtcgtcg cgaaggaacc ggcgatgagc agcgccagca caccggccgc
    22021 cgggattgct gctgccaggt aaccgatggc ctttgcctgc tgatcgccac tgaagttcgt
    22081 ggcgatgaag accgtcaatg cgggagcgat gagggcgatc acggcgccgg atgcagcttg
    22141 cgccacgaac agcattgccg ggctctgact cagggcgacc gcggccattg ctaggccgtg
    22201 aatcgcgacg gcaatctgga agaccagacg cgttccgtaa cgggcgccga tcttggcccc
    22261 caacagaatg aaggcagcca tggcgaaggt gcccgcggtg atcgcggtgc cgacacttgt
    22321 tgcgggcgtg tcgagatcgg tggtgatgcc ggccatcgag acggtcaggg cgttgacggc
    22381 gaacgacgcc tgaatctggg tgaggaccac cacgatgagt ggtagccagg aggcggtgct
    22441 cacggcggcc gttgtggcgg ccgcgccagg ctttacggac atgatgggtc acgccttcct
    22501 cgacactgcg tgtactcgcg acgtgcccgg atcagccacg cacggctaca ttagccggaa
    22561 ttgtgctgaa tggtcgcctg caagtggttg gtttcttcgc ggtagaccac catctcccgg
    22621 tgcaaggcgc gacggaagcg cggttgctcg gccaggagta cggccagcac ggtcagcaac
    22681 agccacgtcg cggccgcgct cgcgaggagc agcaggaccg gaatccacgg accgcccatc
    22741 tgctcgagca gcgtcgtctt tgcccagacg cgccagtaga gcatcagatt gacgatcagt
    22801 ccgacaccgt acgagatgac gaaggacagc aggaactgct tccacgtgcc gtcgtggcgc
    22861 cgcgccgtca tcggttctgc ccgcagcggc aagctcaccg acatcacgtt cgcgaccccc
    22921 aaccagagca ggatcatggt cagcacctgg ccgcacgcct tcaccaggtc agcactgctt
    22981 ccggagcgcc acgcgaggac ggcgctgagc aggaacccgg cgctgccgac gaggagcagc
    23041 atcaccgcgt ttttcgcgac gagcacgtgc cagagcctcg ttccaccgga caacgcagcg
    23101 cgcacgcggc cggcgtcgaa gctgagcgca ttggtgcaca cgacgcttcc gaccacaccc
    23161 gagagtgcat acagcgcaag gtaaggcagt cgatcttcct tggtgtccca ctggaagagg
    23221 cgaatgaatg ccaggtacgc caagcccatt ccgaggctca gccccagccg aaaagcgatc
    23281 gaccgaggct taccactcac cacgtgccgg gcttcctcac ggatccggga gccgagatcc
    23341 tgcacgtgcc ggacgacggg gttgcccgag ttcagcggga cgtaaccacg gatcgcggcg
    23401 gcgacggtat cggtgtcacc ggcatcgagc gcggcgacgc gtgcttcgag aaccgcaagg
    23461 tgggcggcgc gcaaggctat ccgtgcggtg gtcaccgcgg cgacggcgtc ggcctcggcc
    23521 tgcgcggcgg tgccgatgcc ggcgtcggcg ggcagtggcg gctgcaacgt cgtgatcagt
    23581 tcgagttggc gcgccatgtg cggcgacggt gacaacccgc tgtacgacgg tcggctcagc
    23641 gctgatcgtt cgtcgtcgag cgaatcacgg acggacgcgg cagccttgcg gacggctgcc
    23701 gggttgtgcc agcgcaccga ccgggcgtca cgctcggcgg cgacggcccg ggaggcaacc
    23761 tcggtcagat cctcgaccgc tgtcaatgtc tgctccactc ggtttaggtt ggtttcatga
    23821 ccaccaactc ggaaaaggaa gatctccagc ggtacctgca ggcagcacgt gatgcgctcg
    23881 tctggaagct cgacgggctg tcggagtatg acattcggcg tccgatgacc cggacaggga
    23941 ccaacttgtt gggactggtc aaacacatga tcggcgtcga gctcgggtat ttcggtccga
    24001 cgttcggccg tagggttccc gatctccccg cgtggttgcg ttcggaggaa ctcaacgtcg
    24061 acatgtgggc ccgcgccgac gagtccactg ccgacatcgt cgaaacctat cgccgcacct
    24121 gggctttcgc cgacgccacg atagaggagc acgatctgga cgcccccggc ttcgtgaagc
    24181 actggccgga ggatcgtcgc gacgtcacac tgcaccggat actcgttcac gttgtcaccg
    24241 agatccatcg gcacgccggc cacgcggaca tcgtgcggga gctgatcgac ggcgccgctg
    24301 ggatgaaggc gggcgacaac aatctggctc ccggtgatga ggcgtggtgg gccgagtaca
    24361 ccgaccgtct ggagacggcg gcacgcgagg cccaccacgc ctgaactact cgaataccgc
    24421 tgctgcgccg atcaccacga caacgatcac gaagttgatc agtagcagtg gccagacgaa
    24481 gcgcaggaac ttgtcgtagc cgaccttcgc catggccaac ccgccgacaa cgacgacgtt
    24541 ggtcggggca accatcagca tcaggccgtg gcccatctgg aaggcggtga tgacgagtgc
    24601 tcggctgact ccggcaaagt cgcccagcgg cgcgagcagc ggcatcgcca gggtggcgtg
    24661 accggaactg gacgggatca ggaacgccag cgggatgttg acgagcatca ccaggatcgc
    24721 gaagaccccc gccgaagcgc cgctgaccaa ttgctccatc gcgttgagga tggtgtcgag
    24781 ggtttcggtg ttggtcatga tcaccgagac gccgcgagcg agcaggatga cgatcgccgg
    24841 tccgaccatg tcgccggctc cacgcgtgat cagggagacg atcttcttct cacccatctt
    24901 cgcgactatg ccgacgagaa cggcggcgag gatgaacagc atcgccaatt gcgggaacca
    24961 ccagttcaac tcgaaccagt agggctcggt tgccgtgacg tggtacgcgt cgtactcggc
    25021 cggaccggtg gtggcgccga agatgctcga ccacgggatg acggagaaga tcatcagtcc
    25081 gaaggtgagt ccggtgatga gcagtaccag cttctgagtt ccggtgagct tgccgtcgat
    25141 gtccaccggc tcggccggct cttcgtcttc gtcgtccgcg atgtcgaaac cgacaagcga
    25201 cttggacgga tccttcttca cctttgcggc gtagcggaga acgaatgcca ctgccacagc
    25261 ggtcaatacg atccacagga tcacgcgcag cacgatgccg tcaccgatgg agacgcctgc
    25321 ctcaccggag gcgacgccga tcgagaacgg attgacggtc gacgccatgt ttccgaccag
    25381 agcgccgagg atgatcatgg tggccgcgac catgcggtcg tagcccagtg ccgtcatcag
    25441 cggtatgagc agggcgtaga agccgaacgt ctcgaccgag aagcccattg tcgaaccgag
    25501 cagcgagaac agcaccatga tgacggtgat gagcaaccag cccttgtcgc tgagcttggt
    25561 agcgagttgg gagacagcgg tttccaggct gcgggtggca aagctgaccg agatgaacgc
    25621 accgagcgcc atgatgaaga ggactacgcc gaccgaaccg aagagccgtc cgatgttgtc
    25681 ggtgtcgacg aacccggtga tcgaatcctg gacgccgtag aggccgttca cgggggagag
    25741 gatcagttgc tggattcgtt cccagaacga gagcggagac gtgacggtct cgaagctgcc
    25801 gggaacgggt gagccgtcca cgtcgacgcc gaagcgtccg gccggaatga acagtgccgc
    25861 aacccagacc agaatggtga cgatcgcgag catcgtgacc gcgccgggga actcgaactt
    25921 cttcttggcc ggagtaggtg cggaccccgt gtcggtctcg gtgctcattt cttcccctcg
    25981 aaggtgtgtg cgtactcctg gaagaacagt gctttggcga cgacggcctt ctcgagctcg
    26041 tcgagcagga cgcgttcgtt ggggccgtgg atgttcgcgt aaccgtcggt ggcgccgaac
    26101 aacagcttct cggcggtggg cactgctgta tccaaggcca tcacgagggg gatcgagccg
    26161 ccgcctgcca tcagcccggc cggctcaccc cacgactgcg ataatgcaga caatgccgcg
    26221 tcgaaggccg gtccaccttc ggctgccgca aacccgtcgc cggtttctcc cgcggtgaca
    26281 gtcagttgta aaccgaaggg gcgcagggct tccaggtgtc ggaccagagc agcctgcgcc
    26341 tcgatggcag gttggcgcgg gtgtacgcgc agattgatca cggcgcgggc agtgcttgcg
    26401 acggcgttga ccgcaccgtc cacaggggga gcgtcgattc ccgtcacggt gatggccggg
    26461 cccgaccaga tgcgttcgcc gatgccgccg gttccgagca gcggaagccc gtcttggatc
    26521 tcggcgaggg tgcggaactc gtcctcggtg tatgaactgc cggtccacgg ttcgcgcagg
    26581 aggccgtcga tcgccacgtc accgttgtcg tcgtgcagcg acgccagtgc gcggatgagc
    26641 gcgaggcggg cgtccggtgc ggcgccgccg tagaggccgt tgtgcttgtc ggctccgaga
    26701 gtggtgagtt cgacgatcac ctgggccgat ccgcgcagtg cgacggtcag ggtcggtgat
    26761 ccgggtcgaa cgctcccgac gtcggcgatg accattgcgt cggccgcaaa caattcgggg
    26821 gcttccggcg gatagttgtc gaaggggctg ccgaattctt cctggccttc gatgacgagc
    26881 ttgaccgtca ccggcggctt tccgtcgaag acgcgaagcg cgccgatcat gccgatgacg
    26941 tttgccttcg aatctgccgt accgcggccg taaatcgcgc cgtcacgctt gctcggttcg
    27001 aaaggcggtg aatcccagag ttcgacgtcg tcggcgggaa cgacgtcgta atgcgaatac
    27061 atcaatacgg tcggggctcc ctctggaccg ggaactgttg caatgatgac cggcgcagtt
    27121 ttacctgtta tttcgagttt ctctatcttc gtgactccgg acttctccaa tagagaaacg
    27181 atcaggtcgt gagcctcgaa caggggctcg ctggggaaac cttctgttgc tatcgacgga
    27241 atacgaacaa gttcgacgag ttccgactcc agtgccggca tcaaagctgc aactgtttcc
    27301 ttgattgtgg aataggaggg cgaggcggat tcttccggca cggaattgac tccttctggg
    27361 aaaggcgaaa aacattagag gcagagtctt acacccgata tgcggggtgt gaaagggtga
    27421 cccgaacaaa aagccgaagt ggggcgtcgg gcccgcgatt cttgacattg acgtcaacgt
    27481 caacacacac tgtgacggtg accaccagcg aaacgcagga gcgagcgcgg acagcccgca
    27541 aactcggcga cggtccacgc cgtgccggac tgctcagcac cgctgccctc tgcttcggcg
    27601 aactcggata cgacgccgtg acggtcgaga cgatcacgac cagggctgat gtgtcccggg
    27661 cgaccttcta cgcgtacttc tcgtcgaagg acgaggtctt ccgcgccgtc gccgagatga
    27721 tgtgccgacg cttcctcgac gctcagcaca tggagggccc ggcggccgag gacctacgcg
    27781 aagttctccg aacgaccacg tcggcgttca tcacggccgt gtacacctac ggtgacctgc
    27841 tcgcggtgat cgagcatcgg gcgcgggtgg attccgaggt cgagcgcagt tggtcggcgg
    27901 ttcgcgaaaa gctcgtgagc cgctacgtcc gctttgtcga acggattcga cgggttcacg
    27961 acgtagatcc ctgtgtttcg cccccggtgc tcgttcagat gatctcggac gcacagatgg
    28021 ccggtggagc acgtctgagt aaggcgagtg tcgaagagca gaaccagttc attgcagata
    28081 tgacgacgat gtccgagcgg ttgatcgggt tcgaagagtc gaaatagatt tcttttacga
    28141 atggagtgat cggtggcaga acaagacgtg ctcgaagcgg ctctggcgga gatctctgcg
    28201 ctgcaacaag cgcattggcc cgccggcatt ccccgcgccg tcgagtatcc gctcgaaggt
    28261 gggggacttg tcgattactt gcggcattgg gcggtcgagc ggccggatac tcctgccatc
    28321 gtcttctacg gccgggtcat cacgtattcc gaatacgacg agctttcgga tcgttttgcc
    28381 ggatggctgc tttcactcgg agtcgaacgc ggcgatcgcg tcggcgttca cctggtcaat
    28441 tgccctcagt tccatatcgc gatgctcggc attctcaagg tcggtgcggt tcacgtgccg
    28501 atcaatccac tcttccgtga acatgaattg attcacgaac tcaacgatgc cggcgtcaag
    28561 gtcctactga cgcagaacac cttctcgaag ttggtgaaga aggttcgctc acagactcca
    28621 ctcgaacacg tcgcgaagac tgcagtgtcg gacatgctga cggcgatccc gaccgtcgaa
    28681 ctgcccttcg aggtcgacga tccgcgcctg agcgactggc agtcgatcat caccagtgag
    28741 cgggcgactc ctgtcgccac cgaactcgat tccctcgccg ccctgaacta cacgggcgga
    28801 acgacgggaa tgcccaaggg ctgtgagcac actcagcgcc acatggttta caccgcggcc
    28861 accgcgacgc ttgcgggcgg tgcccaggtg ggtaccaatc cgccggtgtc cctggtgttt
    28921 ctgccgatct tctggatcgc aggtgaggac ttcggcatcc tggttccgct cgtcaacggc
    28981 ggaaccgtgg tcctgctgaa tcgttgggat gcggagacca cgctcgacgc tgtcgaggcg
    29041 tacggcgtga cctcgctggt cggaactgtc gacaattacg tcgaactgat ggacacgcca
    29101 ggattcgcgg agcgaaatct ctcgacactc cagaacgtca tggcagtttc gttcgttctc
    29161 aaactcgatc cggccacgcg ccagcggtgg cgcgaggcta caggcggcgt tctgcgcgaa
    29221 gcgagctacg gcatgaccga aacccacacc gcggacacga tcaccctcgg cttccaggac
    29281 ggcgactacg acctgaaaag cgagccggtg ttctgcggaa ttccggtgcc cggcaccgac
    29341 gttctgatcg tcgatcacga cggcaggccg gttcccgtcg gcgagcacgg gcagatcatc
    29401 gtgcgcagcc catccatcct ttccgcgtac taccgcaacg aggcggccac cgccgacgcc
    29461 atccgtgacg gctggctgca gaccggtgac gtcggaaagt tcagtgagcg tggcggtttg
    29521 cactatttgg cgcggaacaa ggaaatgatc aagaccaacg gcatgagtgt ctttccctcc
    29581 gaggtggaag cgctgctcat gctgcacccg gcgatcgaaa aggctgcggt ggtgccgaaa
    29641 ccggacccgg acaaggggca ggtggctttt gcgtttgtcc aaatggtcga gggttccgac
    29701 actgtggccg acgagatcgt ctcgtgggcg aaggagaaca tggccacgta caaggtgccc
    29761 gaagtggaag tgctcgaggc gcttccgatg acagcgacag gaaaggtgcg caagggcgat
    29821 ctgttcgagc gcactcaggg ggacaagtga gactgctgat tgcgaaccgc ggcgaaattg
    29881 cgctgcggat cattcgaact gcccgtgaac tcgggatcga gacggtgtcg gtgtacgccg
    29941 aggacgacgc gtccagtccg cacgtcgcgg cggccacgga gtcggtgccg ctcggagcgt
    30001 cgggcgcatc cgcgtacctg gatcagagcg cactgctgaa gatcgcggcc gaaacgggcg
    30061 ccacgcacgt gcacccgggc tacggattcc tcagtga
//
