LOCUS       NZ_CP012749            22583 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Rhodococcus sp. 008 chromosome, complete genome.
ACCESSION   NZ_CP012749
VERSION     NZ_CP012749.1
KEYWORDS    RefSeq.
SOURCE      Rhodococcus sp. 008
  ORGANISM  Rhodococcus sp. 008
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Rhodococcus.
REFERENCE   1  (bases 1 to 6570200)
  AUTHORS   Loewen,P.C. and Brassinga,K.
  TITLE     Genome sequence of a ureolytic Rhodococcus species isolated from
            skate fish
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6570200)
  AUTHORS   Loewen,P.C. and Brassinga,A.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-SEP-2015) Microbiology, University Manitoba, 418
            Buller Bdg, Winnipeg, Manitoba R3T 2N2, Canada
REFERENCE   3  (bases 1 to 6570200)
  AUTHORS   Loewen,P.C. and Brassinga,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-SEP-2015) Microbiology, University of Manitoba, 408
            Buller Building, Winnipeg, Manitoba R3T 2N2, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: smrtanalysis v. 2.3.0.140936
            Genome Coverage                   :: 176x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/04/2024 12:54:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,967
            CDSs (total)                      :: 6,896
            Genes (coding)                    :: 6,809
            CDSs (with protein)               :: 6,809
            Genes (RNA)                       :: 71
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 36 of 87
            Pseudo Genes (incomplete)         :: 58 of 87
            Pseudo Genes (internal stop)      :: 13 of 87
            Pseudo Genes (multiple problems)  :: 17 of 87
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:00:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1755976
            Orig. end                         :: 1778559
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP012749.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Source bacteria are available from Dr. A. K. Brassinga, Dept of
            Microbiology, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22583
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="2"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22583
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22583
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12583](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12583
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            732..1742
                     /locus_tag="AOT96_RS08340"
                     /old_locus_tag="AOT96_08330"
     CDS             732..1742
                     /NRPS_PKS="Domain: Beta_elim_lyase (6-289). E-value:
                     6.8e-77. Score: 250.5. Matches aSDomain:
                     nrpspksdomains_AOT96_RS08340_Beta_elim_lyase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007730456.1"
                     /locus_tag="AOT96_RS08340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_08330"
                     /product="GntG family PLP-dependent aldolase"
                     /protein_id="WP_007730456.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.2e-06, bitscore:
                     25.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSYIDLRSDTVTKPDAEMRKAMADAEVGDDVLDHDPTMAALEE
                     EVAHTLGLPAALWVPSGSMGNLIALMLHLHRGDQFLAPEHSHVLGSELGTAAWLAQGMP
                     MALPHDGGPGRPTPETVVKAAGSPGPYFALNTTLLCLENTHNFAGGAVMNPTEWTKLVD
                     AARSRGLKIHLDGARLWNAAVALDVSPTELTSGADTVQVCLSKGLGAPVGSILAASPEL
                     ITEARRIRKMLGGGVRQGGVLAAAGIVALRSQARLSDDHDNAQRLASGLRERGWAVDEP
                     ATNIVLAATADPSVTVAQLAAVDVGAVTVAGKVRFVTHRDVSTADIDAVLSRVTF"
     aSDomain        750..1598
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AOT96_RS08340_Beta_elim_lyase.1"
                     /evalue="6.80E-77"
                     /label="AOT96_RS08340_Beta_elim_lyase.1"
                     /locus_tag="AOT96_RS08340"
                     /protein_end="289"
                     /protein_start="6"
                     /score="250.5"
                     /tool="antismash"
                     /translation="DLRSDTVTKPDAEMRKAMADAEVGDDVLDHDPTMAALEEEVAHTL
                     GLPAALWVPSGSMGNLIALMLHLHRGDQFLAPEHSHVLGSELGTAAWLAQGMPMALPHD
                     GGPGRPTPETVVKAAGSPGPYFALNTTLLCLENTHNFAGGAVMNPTEWTKLVDAARSRG
                     LKIHLDGARLWNAAVALDVSPTELTSGADTVQVCLSKGLGAPVGSILAASPELITEARR
                     IRKMLGGGVRQGGVLAAAGIVALRSQARLSDDHDNAQRLASGLRERGWAVDEPATNIVL
                     AA"
     gene            complement(1744..2598)
                     /locus_tag="AOT96_RS08345"
                     /old_locus_tag="AOT96_08335"
     CDS             complement(1744..2598)
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007730453.1"
                     /locus_tag="AOT96_RS08345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_08335"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_065351560.1"
                     /transl_table=11
                     /translation="MSAARIAVVVRPEQSPEDLVRHARYADEVGIDEVWLWEDCFFGGG
                     IATAATVLAETDRVGVAIGVLPTPMRNTAITAMEISALARVHPDRLRVGFGHGVQSWMR
                     QIGAKAESPLTLLREQFGAVERLLGGESVTVSGRYVNLTDVTLAWPPETVPQLLVGATG
                     PKTLALSGELAQGTVLSGGTTPDSVRRAIAHIGASDHEVVVYVICAFGSGGRERALAEA
                     AASGSESPEDAIAVGNAAEVAAAARRWVAAGATTVVLQPTVDEPDVREFIRFVAQEVQP
                     LVA"
     gene            complement(2595..3458)
                     /locus_tag="AOT96_RS08350"
                     /old_locus_tag="AOT96_08340"
     CDS             complement(2595..3458)
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007730450.1"
                     /locus_tag="AOT96_RS08350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_08340"
                     /product="patatin-like phospholipase family protein"
                     /protein_id="WP_047269365.1"
                     /transl_table=11
                     /translation="MDGVKLGLVLAGGGVAGIAWETGFLLGLQDKSPDTAAALLTADVL
                     IGTSAGSTVSAQIASGVTLQELFDAQTAEATGEIDPKVDVEVLGQMFVDAIAGSQDRAE
                     QLRLLGEAAMRADTVEPAVRRAVIEARLPNRLWPDRELRIPAINAQTGELRVFGNADGV
                     ELIDAVGASCAVPGVWPVVVIEGERYMDGGMASGSNVHLAADCDVVVVLSPAADPAPNL
                     LGGSLREEIDVMTPLPVLPVFADDAVVEAIGTNSLSPTTRRPAAELGREQGRRTADEIA
                     AFLVTA"
     gene            3513..5198
                     /locus_tag="AOT96_RS08355"
                     /old_locus_tag="AOT96_08345"
     CDS             3513..5198
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019745827.1"
                     /locus_tag="AOT96_RS08355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_08345"
                     /product="dihydroxyacetone kinase family protein"
                     /protein_id="WP_039973156.1"
                     /transl_table=11
                     /translation="MFMRSAKTFVPDALRGLIASTDDIAWNPDPGYLTRARPLPRGRVA
                     LVSGGGSGHEPMHAGFIGEGMLTAVCPGLVFSSPNALQIHEGSKAADAGGGVLHIVKNY
                     TGDVMNFGIARELLREDKIDTDVVLVDDDVATERADGSGPGRRGTAATIVVEKVCGASA
                     ARGDDLAEVTRIGQHVAHSARSMAVALRPCTLPGADEPSFDLPAGQMELGIGIHGERGT
                     ERVDALPAPELVRRLTDPIIKSLSLAEGDRVIAVVNGLGATHPLELQLLFAELGDYLDE
                     QGIHIERTLIGTFVTALNMAGASITLVRTDKEILELWDAPTKAPAWPNAIAREYTGMGT
                     RESFGPTFTPDTSRTAESSFVGSWIADWAEKVLDQEPALTDLDRRAGDGDFGTNMVAAL
                     DQLDISAIRDTYSTATIFDAVSQAYLGHAGGTSGALFGIWFRHFFRVAADSADSELDLG
                     AIAAAARAGLDNITSLGGARVGDKTMVDAIVPAVESLEQSVSSEADRDAALASAAEAAA
                     AGAESTETMLANRGRASYVGEAARGVVDPGALLIAWFFASAVGH"
     gene            5300..6922
                     /locus_tag="AOT96_RS08360"
                     /old_locus_tag="AOT96_08350"
     CDS             5300..6922
                     /NRPS_PKS="Domain: AMP-binding (27-436). E-value: 8e-83.
                     Score: 270.2. Matches aSDomain:
                     nrpspksdomains_AOT96_RS08360_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943212.1"
                     /locus_tag="AOT96_RS08360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_08350"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_042451581.1"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-94, bitscore:
                     315.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSTMQDAPLSIAQLLRHGASVHGASEVVTWTESGPRRVSYADVG
                     KRCAQLAHALRGLGVEGDERVATFMWNNSEHLEAYLAIPSMGAVLHTLNIRLFPEQLIH
                     VANHAEDRVIIVDPSLIPLLSPQLPSLTTVKHIVVTGSSTAGLEAPEGVQVHTYEGLIA
                     DQPTEFDWPEVDELSAAAMCYTSGTTGDPKGVVYSHRSIYLHSMQVCMSDGPNLAQGDR
                     ALAVVPQFHAMSWGLPYAAFMIGASLIMPDRFLQPAPLAAIIASEQPTFAAAVPTIWQG
                     LHLYLEQNPQDISSMREVLIGGSAVPPALMHAFEADHNVSVLHAWGMTETSPLGSVARP
                     PAGVTGDAMWKYRYSQGRFPASVEARLIDDDGKVVAHDGVSVGELEVRGPWITGSYYGV
                     DAEDKFNDGWLKTGDVGSITADGFLSLSDRSKDIIKSGGEWISSVDLENAVMGHPDVTE
                     AAVIGVPDEKWDERPLVAVVLRAGSETTMSELQQYLSDKVAKWQLPENWAVVQEVPKTS
                     VGKFDKKRLRADYHEGGLEVTRL"
     aSDomain        5381..6607
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AOT96_RS08360_AMP-binding.1"
                     /evalue="8.00E-83"
                     /label="AOT96_RS08360_AMP-binding.1"
                     /locus_tag="AOT96_RS08360"
                     /protein_end="436"
                     /protein_start="27"
                     /score="270.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="VVTWTESGPRRVSYADVGKRCAQLAHALRGLGVEGDERVATFMWN
                     NSEHLEAYLAIPSMGAVLHTLNIRLFPEQLIHVANHAEDRVIIVDPSLIPLLSPQLPSL
                     TTVKHIVVTGSSTAGLEAPEGVQVHTYEGLIADQPTEFDWPEVDELSAAAMCYTSGTTG
                     DPKGVVYSHRSIYLHSMQVCMSDGPNLAQGDRALAVVPQFHAMSWGLPYAAFMIGASLI
                     MPDRFLQPAPLAAIIASEQPTFAAAVPTIWQGLHLYLEQNPQDISSMREVLIGGSAVPP
                     ALMHAFEADHNVSVLHAWGMTETSPLGSVARPPAGVTGDAMWKYRYSQGRFPASVEARL
                     IDDDGKVVAHDGVSVGELEVRGPWITGSYYGVDAEDKFNDGWLKTGDVGSITADGFLSL
                     SDRSKDIIKS"
     CDS_motif       5840..5896
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AOT96_RS08360_0001"
                     /evalue="4.50E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="AOT96_RS08360"
                     /protein_end="199"
                     /protein_start="180"
                     /score="22.3"
                     /tool="antismash"
                     /translation="AMCYTSGTTGDPKGVVYSH"
     gene            complement(7009..7635)
                     /locus_tag="AOT96_RS08365"
                     /old_locus_tag="AOT96_08355"
     CDS             complement(7009..7635)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007730441.1"
                     /locus_tag="AOT96_RS08365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_08355"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_064443586.1"
                     /transl_table=11
                     /translation="MTGEVESVSSVAVDWRSFPPLVMTDILTASLELFDENGYHGTTVR
                     QIANRVGVTVPALYYHHANKEAVLVALFEISMSELNTRTEAAEAEAGENPVRRFALVVE
                     AIVLYMTHRSRHAALDTEIRHVSPESRSRYAASRKRLELLMRRIVDDGVASGDFAVTDT
                     EETVRAILGMAQSLPRWFQTGGPMSPSQLAQKYVDIAFRTVGYRP"
     gene            complement(7649..8410)
                     /locus_tag="AOT96_RS08370"
                     /old_locus_tag="AOT96_08360"
     CDS             complement(7649..8410)
                     /NRPS_PKS="Domain: PKS_KR (6-163). E-value: 4.9e-13. Score:
                     41.3. Matches aSDomain:
                     nrpspksdomains_AOT96_RS08370_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003875437.1"
                     /locus_tag="AOT96_RS08370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_08360"
                     /product="3-hydroxyacyl-CoA dehydrogenase"
                     /protein_id="WP_003942978.1"
                     /sec_met_domain="adh_short (E-value: 4.7e-30, bitscore:
                     103.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVNDSVAVVTGGASGLGLATTKALLADGASVVIIDLPSSNGEAI
                     AKELGDRVRFAAADVTDEAAVTAALDVAESLGPLRVAVNCAGIGNAVKTVSKKGAFPLD
                     AFKKVIDVNLIGTFNVLRLAAERISKTEPIDGERGVIINTASVAAYDGQIGQAAYSASK
                     GGVVGMTLPIARDLASLLIRVNTIAPGLFKTPLLAGLPEAAQASLGQQVPHPSRLGDPS
                     EYGALAAHIVSNPMLNGETIRLDGAIRMAPR"
     aSDomain        complement(7922..8392)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AOT96_RS08370_PKS_KR.1"
                     /evalue="4.90E-13"
                     /label="AOT96_RS08370_PKS_KR.1"
                     /locus_tag="AOT96_RS08370"
                     /protein_end="163"
                     /protein_start="6"
                     /score="41.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAVVTGGASGLGLATTKALLADGASVVIIDLPSSNGEAIAKELGD
                     RVRFAAADVTDEAAVTAALDVAESLGPLRVAVNCAGIGNAVKTVSKKGAFPLDAFKKVI
                     DVNLIGTFNVLRLAAERISKTEPIDGERGVIINTASVAAYDGQIGQAAYSASK"
     CDS_motif       complement(8318..8386)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AOT96_RS08370_0001"
                     /evalue="7.90E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="AOT96_RS08370"
                     /protein_end="31"
                     /protein_start="8"
                     /score="15.3"
                     /tool="antismash"
                     /translation="VVTGGASGLGLATTKALLADGAS"
     gene            complement(8439..9632)
                     /locus_tag="AOT96_RS08375"
                     /old_locus_tag="AOT96_08365"
     CDS             complement(8439..9632)
                     /EC_number="2.3.1.16"
                     /GO_function="GO:0003985 - acetyl-CoA C-acetyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005264857.1"
                     /locus_tag="AOT96_RS08375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_08365"
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="WP_065351561.1"
                     /transl_table=11
                     /translation="MTKAVIVDVVRIASGKGKPGGALSGTHPVELMAHVLRSITSRNGL
                     DPALVDDVIGGCVGQAGEQALNITRSAVLSAGFPESVPATTIDRQCGSSQQAAHFAAQG
                     VIAGAYDIVIAAGVESMSRVPMGTTTMGKDASGPGVAARYPEGLVNQGVSAELIAAKWK
                     LDRDALDAFSAQSHQRAAEAAAKGLFDKEILPISVTNAAGETVSHIVDETVRASTTAEG
                     LAGLKPSFYSEKYAQRFPEAQWSITPGNSSPLTDGASAALIMSEEMASKLGLTPRARFH
                     SFSVAGDDPIFMLTAPIPATHKVLARAGLSIDDIDTYEVNEAFAPVPLAWAHEFGADPA
                     KLNPWGGAIALGHALGSSGTRLLTTMVNHLEATGGRYGLQTMCEGAGMANATIIERI"
     gene            10001..12583
                     /gene="lanKC"
                     /locus_tag="AOT96_RS08380"
                     /old_locus_tag="AOT96_08370"
     CDS             10001..12583
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019745831.1"
                     /locus_tag="AOT96_RS08380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_08370"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_065351562.1"
                     /sec_met_domain="micKC (E-value: 1.6e-193, bitscore: 643.5,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.7e-13, bitscore: 49.0,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 1.3e-05, bitscore: 23.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6.8e-05, bitscore:
                     20.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLRYVAFTRADPHFYDRIRTVTRPDTSTDQHFIPAKSVDWSLWR
                     RGPQSGPWNYFQPPDGLLPEQGWKIHCSATQANAQELLDTVSVYCGHNHVPFKFLRTAA
                     DLMLSNSKQANRTSSGKFITIYPADGVATQRVITELDKLVTGADGPYILSDVRWNRGPL
                     YLRYGAYLPMQTYDSFGDRVPAIRRPDGSLEPDVRGTSFRTPDWVQIPDFVRAQQDKLK
                     SHDEFPYSINEALHFSNSGGIYSAFDDAGIDLVIKEGRPFTAPDANGRYAIDRIRNEYD
                     KLTHLADNPYAPSAIRLFEREGHHFLVTERAAGTPLNQEVALRHPLIRADQTLSSRTEY
                     RTWALDIAQQLTTAVESFHNAGIVHADLHPGNVMCSPSGIRIIDFEMAHNIDEHPPRST
                     GAPGYTAPRQLTGIAADRYSLGCIELGLFVPLTTLFPLDRNKIPELIDYAVSRFDLPRA
                     FGASLYSMLDVQAPAPKNRPHRWDTSSNETLQRTAALLRCGILASLDLARADRLFPGDI
                     AQFEVNGYGIAHGSCGNLLADVLPADTLESVLEWTEHQVDSDTQPKFGFFDGLAGAVHT
                     FRHHGRHSTADRWVETLRRAPLDDIDSSLFSGLSGIGCLLLEESVSRPTVSPTLAVVTE
                     TLRERISAARLHVRDAGGTPWAVAGRGGLMRGPSGQALFWTRHYELSGDPRSLEHARQL
                     VDIDLSVMSMCPDGSMQLREERRTMPYLGSGSVGVGLVLLQLLRHVDEPRYAAAVRAIS
                     RAATVEFTAQAGLLNGRAGLMLFLSELSKTPYAGADCEQTLAQQFQLLGLHSLNHAGGL
                     HFPGEQNLRLSTDWATGSAGILALLPYTGSATARQSFPLMCASNCHIA"
     CDS             12715..12834
                     /gene="allorf_1768691_1768810"
                     /locus_tag="allorf_1768691_1768810"
                     /protein_id="allorf_1768691_1768810"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTMDAILSLQDLSVAAGNVGDAGQLEQNAAISSLSFFCL"
     CDS_motif       12715..12777
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTMDAILSLQDLSVAAGNVGD"
                     /locus_tag="allorf_1768691_1768810_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12778..12834
                     /prepeptide="core"
                     /locus_tag="allorf_1768691_1768810_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.20"
                     /molecular_weight="1845.1"
                     /monoisotopic_mass="1843.9"
                     /core_sequence="AGQLEQNAAISSLSFFCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTMDAILSLQDLSVAAGNVGD"
                     /leader_location="[12714:12777](+)"
                     /alternative_weights="1863.1"
                     /alternative_weights="1881.1"
     gene            complement(13222..13356)
                     /locus_tag="AOT96_RS36320"
     CDS             complement(13222..13356)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AOT96_RS36320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_256082940.1"
                     /transl_table=11
                     /translation="MNSSDLGSVSALLPMMLTAFKSIITMPFALSVDFGLDVPFNPFK"
     misc_feature    complement(13608..13621)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            13841..14827
                     /locus_tag="AOT96_RS08385"
                     /old_locus_tag="AOT96_08375"
     CDS             13841..14827
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AOT96_RS08385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AOT96_08375"
                     /product="hypothetical protein"
                     /protein_id="WP_156778937.1"
                     /transl_table=11
                     /translation="MIFLLILTAALSGWFVQRSGESWDFGDICSRWYDGGGSCRADTAL
                     TLTTLLVLLLPFASGMLVGVTTFARDFEQGPENLDFLESTSLVRWYFLRVLVVFVPITL
                     AMAVLGLVLGWTQTLGRGQAATNEATSFSLMEFPNFQTTGIVVGAYTFLAMTTGSAAAL
                     LIRNTVFAMVMTLLAFLIVPVALSATMREHYLAPDTEVQPIDGLARAAEYAPSPYENLD
                     SRWVIDAGFADTDGNMIDADYTMCWGSDNSDRKQQDLEVDNCLREQGIDHYAVIYHPQS
                     RYWQFQFIETAVMLLCSGLMVALALVGARGRRRRPAYNRLSEMSKSI"
     misc_feature    14861..14876
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.95"
                     /tool="antismash"
     misc_feature    complement(14862..14875)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.58"
                     /tool="antismash"
     gene            14890..16128
                     /locus_tag="AOT96_RS08390"
                     /old_locus_tag="AOT96_08380"
     CDS             14890..16128
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019745836.1"
                     /locus_tag="AOT96_RS08390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_08380"
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="WP_065352793.1"
                     /transl_table=11
                     /translation="MDSRDAWQLDGEGLKGEVLDLVRVRHELQSRLVLLIVEMFSREVL
                     GGKGFRAIAQWLHGSTNLEIGECSLLVGLARLLMLEPVVADAFHRGDVDALKARQVASF
                     CQHPPKNMTLADVDKARGILLSLASKNIADCDAVRAAIRRIEKQYGKREDGVPVGEDSE
                     RNEFYASKGLYGRVTVKGDLDAINGARLITLLSSLSAPTPEKDGVKDTRTPALRRADGF
                     CELLRWYERAGLGPIEGGVKPHITVTASAKDMTDLKVLKDLLPSTEELGFAWTDWVGPI
                     SIDTARMLACDCTVTRILLDESGVPLDCGKEARTATVPQRRALTVRDGRCAFPGCGTPS
                     GWCDAHHIVHWNDGGPTDLDNLILLCGHHHRTMHHTEWRVEIGPDRKTVFYPPMSIDPY
                     QQPIGGNSPPTAA"
     gene            complement(16240..17142)
                     /locus_tag="AOT96_RS08395"
                     /old_locus_tag="AOT96_08385"
     CDS             complement(16240..17142)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007730424.1"
                     /locus_tag="AOT96_RS08395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_08385"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_083197597.1"
                     /transl_table=11
                     /translation="MGCSGTGSHRIAREDRTEADVIRSILSNLALRPPTRLRSLVLSRG
                     VTLSDKTIVLTGASSGIGEATAHLLARRGAEMILVARGEENLEHVRDEIHRRGGWAHIV
                     PADLSRGEAVDELAETIADRFGSVDILVNNAGRSIRRTALDSVDRFHDYERTMALNYFG
                     PSRLTLRLLPAMLEAKSGHIINVGTWGVTAGVMPRFSAYHASKSALSAFGRSLGAECHG
                     TGVDVTTVQFPLIRTPMIAPTADYVSQPALTADQAASWILRAINTRPVELYPRYAGLLR
                     AIDVVSPSATDALVRRAGI"
     misc_feature    complement(17159..17173)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.78"
                     /tool="antismash"
     gene            17360..18367
                     /locus_tag="AOT96_RS08400"
                     /old_locus_tag="AOT96_08390"
     CDS             17360..18367
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AurF"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943163.1"
                     /locus_tag="AOT96_RS08400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_08390"
                     /product="diiron oxygenase"
                     /protein_id="WP_003943163.1"
                     /sec_met_domain="AurF (E-value: 1e-113, bitscore: 377.7,
                     seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLTSPLDKRGEASDDSYNETLRLLSEGSVHKHFDPYLDIDWDSP
                     EFAVVPNDRRWILPAETDPLGAHPWYQSQSEARQIEIGMWRQANVAKVGLQFENILIRG
                     MMQYVFSLPNDSAEARYCTHESVEECNHTMMFQEMVNRIGADAPGMSRPMKMLAPFIPL
                     AAGPFPELFFVGVLAGEEPIDHIQKSILRAGGQIHPIMQSVMAIHVAEEARHISFAHKL
                     LSRRIPLMSRPNRFVLSLLFPIVMRILCDAIVIPPKSFWKQFDIPKSVKKDLFWDLPES
                     RQTLRNYFGDVRMLATDTGLMNRASRLVWKACKMDGRASRFRSEPHRSSHNAAA"
     gene            18401..20128
                     /locus_tag="AOT96_RS08405"
                     /old_locus_tag="AOT96_08395"
     CDS             18401..20128
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1285: ferredoxin fdxC"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019745838.1"
                     /locus_tag="AOT96_RS08405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_08395"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_064113617.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1e-07, bitscore:
                     30.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPHVVTQSCCSDASCVYACPVNCIHPTPDEPDFLTAEMLHIDPQA
                     CVDCGACVSACPVDAIVPESKLTDPQRVFLSINADFYKEERPRPLLAKVIPAAHVDKGR
                     PPLRVAIVGSGPSAMYAADELLTQPDVQVNVFDRLPVPYGLVRAGVAPDHQKTKQVTRL
                     FDKIAAQKGFEFYLNVEIGKHISHSELLENHHAVLYAVGASSDRGLGIPGADLPGTASA
                     TDFVAWYNGHPDHADDVFDLSHRRAVIIGNGNVALDVARILTADPEKLAGTDISAHALA
                     ALRKSRVEEVVIVGRRGIAQSAFTVPEFTGLMALPDIELSVGPDDMVLDSATEELAKRG
                     ELPHAVEQKLRLLEALKNRDHVDVGNKRITLRYLLTPTSITGDDQVSGIEFARNALVDA
                     NGTVQIEATGDTETIDTGLVLTSIGYRGVPIPGVPFDERASVIPNENGRVLEAPNGDPA
                     TGVYATGWIKRGPSGFIGTNKSCAQETIRMLVDDFNDGRLTNPVADDSAVDRLVRARQS
                     DVVDREGWHAIDKAELERGAAHDRVREKVLDQVEITSILDAAARVKPARRFGRPVRAR"
     gene            20341..20814
                     /locus_tag="AOT96_RS08410"
                     /old_locus_tag="AOT96_08400"
     CDS             20341..20814
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019745839.1"
                     /locus_tag="AOT96_RS08410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_08400"
                     /product="OB-fold domain-containing protein"
                     /protein_id="WP_065351564.1"
                     /transl_table=11
                     /translation="MSETATPAPNGSVTPAVEGWFTTGDEPALIGTKCQSCGTISFPRE
                     ATFCKNPSCFSEEFDDVELSRSGTVWSYTDAQYQPPPPYIPRSDPYEPFALAAVELPEG
                     IVILGQVADGFGVDDLKVGNTVELVVEPLYTDETGVRTTWRWKPVAADQESQS"
     gene            20811..22001
                     /locus_tag="AOT96_RS08415"
                     /old_locus_tag="AOT96_08405"
     CDS             20811..22001
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007730416.1"
                     /locus_tag="AOT96_RS08415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOT96_08405"
                     /product="lipid-transfer protein"
                     /protein_id="WP_007730416.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 4.3e-06, bitscore:
                     24.9, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKDVAVLGVGMHPWGKWGQSFVKYGVAAARAALADSGVNWQDVD
                     FIVGGETVRNGYGGYVAGATFAQALGWNGARVATSYAACATGAQALDTARARILAGLSE
                     VALVVGADTTPKGFLAPVAGERWDDPDWLRFRLMGMTNPAYFALNARRRIDLYGATAED
                     FANVKVKNAKHGLNNPNARYRKEVTVENVLASPVVSNPLHLLDICATSDGGAAILLTSM
                     EYARKMGIAEPVRIKAISTVTPTFPQTIMDMPNFSTDSSSAVPAPERTFKESIGYAAYE
                     EAGISPEDVDIAEVYDLATSVELDWIEDLALCKRGEAEHLLRAGDTSIGGRIPVNPSGG
                     LACFGEAVPAQALAQVCELTWQLRGQAEGRQVEGARIGITANQGLFGHGSSVIVSA"
ORIGIN
        1 gcacgccacc agatttcccc acgtgttggg cccgttacgg ctccgcggct ggacatggtc
       61 gatggtcgtt gcccgggcgg cgcagtacgc acatcgacga ccgtcccggt cgaagacacc
      121 ggcaaaagtg gcccgactgg aatcggtgac cgtcacccgg tgagcaacgt acacgtactc
      181 gtcgagcagg atcgtcctcg gcagtgggat ttcgacgtgc ttggagcgca ccggaaatat
      241 cggggtcacg tcttcggtgg actgcgcgga gccggtggcg atcaggacga ccgcacgatc
      301 ggcgctcact tcaccgaggt actcgtacgt agcgttgagt acccggacgg ggcggttcat
      361 ccaactgtga gcaagtgcgc ggttcgggtt ccgcatgaga gttctcagtt cgtgtcgagg
      421 agtgaaactc ctggacacga agacgggtca ggagcaaatg caagaaatgg ggaacggcat
      481 atatccagcg ccgctctgtt ccccgaatgc gggatgggaa ataccgcggg gtgagtgccc
      541 gcgcaggtgc aacgcttgct tccagtcgcg catgcctgtc cccttccact tcttgttctc
      601 gtcaccggct attgccgacg ctcatcatca cacggaaggc atcctcagcg atatcgattt
      661 atcaggccgg aagagccgtc ctggaaatac cgcggtttga cgccggaaca cgcggcttga
      721 tcgaatgagc catgacttcg tcgtacatcg acctacgctc ggacaccgtc accaagcctg
      781 atgcggagat gcggaaggcg atggccgacg ccgaggtcgg tgacgacgtc ctcgatcacg
      841 acccgaccat ggcggcgctc gaggaagagg tggcgcacac tctgggttta ccggcggcac
      901 tgtgggtgcc gagcggatcg atgggcaacc tgattgcgct gatgctgcac cttcaccgcg
      961 gcgatcagtt cctggcaccg gaacactctc acgtcttggg ctccgaattg ggcaccgctg
     1021 cctggctcgc ccagggaatg ccgatggcgt tgccgcacga cggcggaccc ggacgtccca
     1081 cccccgagac tgtcgtgaag gcggcgggct cccccggccc gtacttcgcg ttgaacacca
     1141 cgctgctctg tctcgagaac actcataact tcgccggcgg tgccgtcatg aatccgaccg
     1201 aatggacgaa gctggtcgac gcagcgcgat cacgcggctt gaagattcac ctcgacggcg
     1261 cccgtctctg gaatgccgct gttgcactcg atgtttcgcc caccgaattg acttccggcg
     1321 ccgataccgt tcaggtgtgc ctgagtaagg gactcggtgc gccggtcggc tcgatactcg
     1381 ccgcatcacc cgaattgatc accgaagccc gaaggatccg caagatgctc ggcggcggcg
     1441 ttcgtcaggg cggagtgctg gccgcagccg gcatcgtcgc gttgcgctca caagctcgcc
     1501 tctccgacga tcacgacaac gcgcagcgcc tcgcgtcggg gcttcgtgaa cgcggttggg
     1561 ccgtcgacga acctgccacc aacatcgttc tggccgcgac agccgatccg tcggtcaccg
     1621 ttgctcagct cgccgctgtc gatgtcggcg cggtcaccgt tgccgggaag gttcggttcg
     1681 tgacacatcg cgacgtgagc actgccgaca tcgacgcggt tctgtccaga gtaaccttct
     1741 gaactacgcc accaggggtt gaacctcctg cgcgacaaag cgaatgaact cgcggacatc
     1801 cggctcgtca acagtcggtt ggagtaccac ggtggttgca cctgctgcaa cccatcgccg
     1861 tgctgctgcc gcgacttcgg ccgcgttgcc cacggcaatc gcatcctccg gcgactcgct
     1921 accggacgct gcggcctcgg caagggcgcg ctcacgaccg ccggaaccga aagcacagat
     1981 gacgtagacg acaacctcgt gatccgacgc cccgatgtga gcgatcgccc gacgcacgct
     2041 gtccggggtc gtcccacccg agagcacggt gccctgcgcc aactcgccac tgagtgccaa
     2101 agtctttggc cccgtggcgc cgacgagcaa ctgcggcacc gtctccggtg gccacgccag
     2161 cgtcacgtcc gtgagattca cgtatcgacc ggacaccgtc accgactcac cgcccagtag
     2221 cctctccacc gctccgaact gctcccgcag gagggtcaac ggcgattcgg ctttggcccc
     2281 gatctgccgc atccaactct gaacgccgtg accgaagcca acccgtagtc gatccggatg
     2341 aactctggcc agcgctgaaa tctccatcgc cgtgatcgcg gtgttgcgca tcggggtcgg
     2401 cagcacaccg atcgccacac ccacacgatc ggtctcagcc aatacagttg cagcagtggc
     2461 tattcctccg ccgaagaagc agtcttccca caaccagacc tcgtcgatac cgacttcgtc
     2521 tgcatacctg gcatgtcgaa ccagatcttc cggagattgc tccgggcgca cgacgacggc
     2581 aatccgtgcg gcgctcatgc cgtcaccaga aacgcggcga tctcgtcggc ggttcgacgg
     2641 ccctgttcgc ggccgagttc ggctgcgggg cgcctggttg tcggtgaaag cgagttcgtt
     2701 ccgatcgctt cgacgacggc gtcgtcggcg aagacaggca gcacgggcaa gggcgtcatc
     2761 acgtcgattt cctctcgtag actgccgccc agaagattcg gggcggggtc ggctgcgggt
     2821 gaaagaacca cgaccacatc gcagtcggca gccagatgaa cattcgagcc actcgccatt
     2881 ccgccgtcca tgtaccgctc gccctcgatc acgactaccg gccacacccc tggtacggcg
     2941 caacttgctc cgactgcgtc gatcagttct acgccgtcag cgttgccgaa caccctcaac
     3001 tcaccggtct gtgcgttgat cgccgggatg cgcaactccc ggtcgggcca caaccgattg
     3061 ggcagcctcg cctcgatgac cgcgcgacgc acggcaggtt cgacggtatc ggctctcatc
     3121 gctgcttcgc cgagcaaacg gagctgctcg gcccggtcct gcgatcctgc gatcgcgtcg
     3181 acgaacatct gaccgagtac ctcgacatcg accttcgggt cgatttcgcc ggtcgcctcc
     3241 gctgtttgtg cgtcgaaaag ctcttgcagt gtcacgccgc tcgctatctg agcgctcacc
     3301 gtggaacctg cggaagtgcc gatcaacacg tccgccgtca gcagcgcagc ggcagtgtcc
     3361 ggtgatttgt cctgaaggcc caacagaaaa cctgtttccc aggcgattcc cgcaacgccg
     3421 ccaccggcaa gtaccaaccc caatttcacg ccgtccacct ctcgtcgatc gtgatccgtg
     3481 cccgaagtcg acgttagacc taccctgaag tgatgttcat gcgcagcgca aagacatttg
     3541 ttcccgacgc actccgtggt ttgatcgcat ccaccgacga catcgcgtgg aatcccgacc
     3601 ctgggtacct cacacgcgca aggccacttc cccgcggacg ggtcgcgctc gtctccggcg
     3661 gcggttcagg ccacgaaccc atgcacgccg gattcatcgg cgaaggaatg ctcacagccg
     3721 tctgccccgg attggtcttc agctcaccca atgcacttca gatccacgag gggtccaagg
     3781 ctgccgacgc cggcggcggc gtccttcaca tcgtgaagaa ctacaccggc gacgtgatga
     3841 acttcggtat cgcccgagag ttgctacgcg aggacaagat cgatacggac gtcgtcctgg
     3901 tcgacgacga cgtcgcgacc gaacgcgcag acggcagtgg cccggggcga cgcggtactg
     3961 cggcaaccat cgtggtggag aaggtctgcg gcgcatccgc cgcccgcggc gacgacctgg
     4021 ccgaggtgac ccggatcgga caacacgtcg cgcactccgc tcggagcatg gccgtcgccc
     4081 ttcgcccatg cactttgccg ggggctgacg agccgtcgtt cgacttgccg gcgggtcaga
     4141 tggaactcgg tatcggcatc cacggcgaac gcggcacaga acgcgtggac gccctgcccg
     4201 caccggaatt ggtgcggcgg ctgacggacc cgatcatcaa gtccctgagt ctcgccgaag
     4261 gcgaccgcgt catcgccgtc gtcaacggtc tcggcgccac ccacccgctg gagttgcaac
     4321 ttctgttcgc cgaactcgga gattatctgg acgaacaggg aattcacatc gagcggacac
     4381 tgatcggaac cttcgtcact gcattgaaca tggcaggcgc gtccatcacc cttgttcgca
     4441 cagacaaaga aatcctcgaa ttatgggacg caccaacaaa agcgcccgcc tggccgaatg
     4501 ctatagcgcg tgagtacacc ggcatgggca cgcgcgaatc tttcggtccc acattcacac
     4561 ccgacacctc acgcaccgcc gaaagcagct tcgtcggaag ctggattgcg gactgggccg
     4621 agaaggtact ggatcaggaa ccggcactga ccgatctcga ccgacgagcg ggcgacggcg
     4681 atttcgggac caacatggtg gccgcactgg atcaactcga catctcggcg atccgtgaca
     4741 cgtactccac cgcaacgata ttcgatgcag tctcacaggc gtacctcggc cacgccggtg
     4801 gcacctccgg cgcattgttc ggcatctggt tccggcattt cttccgcgtt gccgcagact
     4861 cggcggactc cgaactcgac ctcggcgcga tcgcggctgc agcgcgagcg ggactcgaca
     4921 acatcacctc gctcggcggc gcacgcgtcg gcgacaagac gatggtcgac gcgatagttc
     4981 cggcggtcga gtcgttggag caatccgtga gctcggaagc cgatcgagat gctgcgctgg
     5041 cgagcgcagc ggaagccgca gcggccgggg cggagtcgac cgaaaccatg ctcgcgaacc
     5101 gcggacgtgc aagttatgtg ggcgaagccg ctcgcggagt agtcgatccg ggagcgctac
     5161 tcatagcgtg gttcttcgcc agtgcagtgg gtcactagcg agcacttcgg ggctgtgact
     5221 aatctggcag ccacagcaca tcgtttgtga cgacccgtgg gcaaaagcac cggtctcaca
     5281 caccacacag gagcagccca tgctgagcac catgcaagac gcccccctct ccattgctca
     5341 acttctccgc cacggtgcct ccgttcacgg cgcctccgag gttgtcacgt ggaccgagtc
     5401 cggcccgcgc cgtgtgtcct acgctgacgt cggcaagcgc tgtgctcagc ttgcgcacgc
     5461 cctgcgcggg ctcggcgtcg agggtgacga gcgagtcgcc acgttcatgt ggaacaactc
     5521 cgagcacctc gaggcgtacc tggcgatccc ctcgatgggc gctgtgctcc acaccctgaa
     5581 cattcgtctg ttccccgagc agttgatcca tgtcgccaat cacgccgagg accgcgtgat
     5641 catcgtcgac ccgtccctga ttccgcttct ctctccgcag cttccgtcgc tgaccaccgt
     5701 caaacacatc gtcgtcaccg gctcctccac tgcaggactc gaagctcccg agggagtgca
     5761 ggttcacacc tacgagggct tgatcgccga tcagcccacc gagttcgact ggcccgaggt
     5821 cgacgaactg agcgctgccg caatgtgtta cacgtccggc accacgggtg accccaaggg
     5881 cgtcgtctac tcccaccgtt cgatctacct gcactccatg caggtctgca tgagcgacgg
     5941 ccccaacctc gcgcagggcg atcgtgcact cgccgtggtg cctcagttcc acgccatgtc
     6001 gtggggactt ccctacgccg cgttcatgat cggcgcctcg ctgatcatgc ccgaccgctt
     6061 cctccagcct gccccgttgg ctgcgatcat cgccagcgag cagccgacgt tcgccgcggc
     6121 cgtacccacc atctggcagg gcctgcacct ctacctcgag cagaacccgc aggacatctc
     6181 ctcgatgcgt gaggttctga tcggcggctc cgcggtaccg cccgccctca tgcacgcatt
     6241 cgaagccgat cacaacgtct ccgtcctgca cgcctggggc atgaccgaaa cctccccgct
     6301 cggatccgtt gcccgtccgc cggccggtgt caccggcgac gcgatgtgga agtaccgcta
     6361 ctcgcagggt cgattcccgg catccgtcga ggcgcgtctc atcgacgacg acggcaaagt
     6421 tgttgcacac gacggagttt ccgtcggcga actcgaagtg cgcggccctt ggatcaccgg
     6481 gtcgtactac ggcgtcgacg cggaagacaa gttcaacgac ggctggctca agaccggcga
     6541 cgtcggatcc atcacggccg acggcttcct gagcctgtcc gaccgctcca aggacatcat
     6601 caagtccggc ggcgaatgga tctcctcggt cgacctcgag aacgccgtca tgggtcaccc
     6661 cgacgtcacc gaagctgccg tcatcggcgt gccggacgag aagtgggacg agcgcccgtt
     6721 ggttgcggtt gtccttcgcg ccggttccga aaccaccatg tccgaactgc aacagtacct
     6781 ttcggacaag gttgccaagt ggcagctgcc cgagaactgg gccgtggttc aggaagtccc
     6841 gaagacgagc gtcggcaagt tcgacaagaa acgccttcgc gccgactacc acgagggcgg
     6901 actcgaagtt acgcgactct gacacggagt gaatgtcgaa gtctgaatac tgaaggtggg
     6961 caacaggttt tcgacctgtt gcccaccttc gttcacgagc gaggcacttt acggccgata
     7021 gccgaccgtg cgaaaagcga tgtcgacgta cttctgcgcc aattgcgacg gcgacatcgg
     7081 accgccggtc tggaaccaac gcggcagtga ctgcgccata ccgagtattg cccggacggt
     7141 ctcttcggta tcggtgaccg cgaaatctcc cgatgccaca ccgtcgtcga cgatcctgcg
     7201 catcagcaac tcgagccgct tacgactggc ggcgtaccga cttcgacttt ccggtgagac
     7261 atgccggatc tcggtgtcca acgcagcgtg ccgcgaccgg tgggtcatat agagaacaat
     7321 cgcctccacc accaaggcga agcgtcgtac cggattttcg ccggcctccg cttctgccgc
     7381 ttcggttctg gtattcagct cactcatcga gatctcgaac aaagcgacga gaactgcctc
     7441 tttgttcgcg tggtgatagt agagcgcggg aacggttacc ccgacacgat tggcaatctg
     7501 gcgcaccgtc gtgccgtggt aaccgttctc gtcgaacagc tcgagcgaag ccgtcaggat
     7561 gtcggtcatc accagcggcg ggaaggacct ccagtccact gccaccgagc tcaccgactc
     7621 cacctcgcca gtcatgtgat agccgaaatt accgcggtgc catacggatt gcaccgtcga
     7681 ggcggatcgt ctcaccattg agcatggggt tggaaacgat gtgcgcagca agcgcgccgt
     7741 actcgctggg atcacccagg cgagaggggt gaggcacctg ctgacccaac gacgcctggg
     7801 ctgcttcggg cagtccggcc agcaacgggg tcttgaacaa gccgggtgca atggtgttga
     7861 cgcggatcag cagcgacgcg aggtcacggg cgatgggaag cgtcataccg acgacgccgc
     7921 ccttcgacgc ggagtacgca gcctgcccga tctggccgtc atacgctgcg accgaagcgg
     7981 tgttgatgat gacgccgcgt tcaccgtcga tcggctcggt cttcgaaata cgttccgcag
     8041 caagacgaag gacgttgaag gtgccgatca gattgacgtc gatgaccttc ttgaacgcgt
     8101 cgagcgggaa agcgcccttc ttgctgaccg tcttgactgc gttgccgatt ccggcgcagt
     8161 tgactgccac gcgcaggggt ccgagggact cggccacgtc gagtgccgcg gtgaccgcag
     8221 cctcgtcggt gacgtctgca gccgcgaagc ggacccggtc gccaagttcc ttggcgatgg
     8281 cttcaccgtt ggacgacgga aggtcgataa tgacgacgct ggcaccgtcg gcaagaaggg
     8341 ctttggtcgt agccaggccg aggccggatg ctccaccggt gacgacggcg acgctgtcgt
     8401 tgacgatcat gagagttcct ttcgaaaggt tatgtgtttc agatgcgttc gatgattgtg
     8461 gcgttggcca tgccggcgcc ctcgcacatg gtctgcaatc cgtagcgtcc gccggtggcc
     8521 tcgaggtggt tgaccatcgt ggtcagcaga cgagtacccg aggaccccag ggcatggccg
     8581 agtgcaatcg cgccgcccca cgggttgagc tttgccgggt cggcgccgaa ctcgtgagcc
     8641 caggcgagtg gaacgggagc aaatgcctcg ttgacctcgt aggtgtcgat gtcgtcgatg
     8701 ctcaggcccg cgcgagcgag caccttgtgg gtggctggga tgggtgcggt gagcatgaag
     8761 atcgggtcat cgcccgcaac ggagaaggaa tggaaacgag ctcgcggcgt cagccctagc
     8821 ttcgacgcca tttcttcgct catgatcagt gctgcggacg cgccgtcggt gagcggcgac
     8881 gagttaccgg gagtgatcga ccactgcgcc tcggggaagc gctgcgcgta cttctccgag
     8941 tagaacgacg gcttcaaacc ggcgagtccc tcggcggtag tagacgcgcg aaccgtctcg
     9001 tcgacgatat gcgagacggt ctcaccggcg gcgttggtca ccgagatcgg cagaatctcc
     9061 ttgtcgaaga gccccttcgc cgctgcctct gctgcccgct ggtgggactg cgcggagaat
     9121 gcgtcgagag cgtcgcggtc aagcttccac ttggcggcga tcaattctgc agagactccc
     9181 tggttgacca ggccttcggg gtagcgagcc gcgacgcccg gaccggaagc gtccttcccc
     9241 atcgtcgtgg tacccatcgg gacacgactc atggattcga cgcctgccgc gatcacgatg
     9301 tcgtaggccc cggcgatcac gccctgcgcc gcaaagtgcg cagcttgctg acttgatccg
     9361 cactggcgat caatcgtggt ggcgggtacc gactcgggga accctgccga caggaccgcg
     9421 ctgcgggtga tgttgagcgc ctgctcaccg gcctggccga cgcaaccgcc gatcacgtcg
     9481 tccaccaggg cggggtcgag gccgtttcgc gaggtgatgg aacgcagaac gtgggccatc
     9541 agttcgacag ggtgcgtccc ggacagtgct ccgcccggct ttcccttgcc ggacgcgatc
     9601 cggactacat cgacgatcac tgccttggtc atcttcgttc ccttcgagga cgtgcattgc
     9661 tggggcggtc cggcacccga gtttcgtggc gccgggtacc ggaccgagat cgagggagca
     9721 ccctgactta gcgctcgcta aagaactacc accgacttga tcctctcgtc aagagggggc
     9781 ctccgaactc gaaacaaatg cggccgacta aaagctgggc gatcagtgac ctcgcctggc
     9841 ccacgccatt cattagtact ttcgaatgat aggttttcaa tcttcgcccg aaatgtccgg
     9901 aatcggataa ccttccgcca caagcaatcc aagccacagg ggattcgggg cgtggcacca
     9961 atcgatgaca accgcagggg gactgaccgg gaggtttggc gtggacctgc gatacgttgc
    10021 cttcacgcgt gccgacccgc atttctacga ccgaatcaga acggtcaccc gaccagatac
    10081 atcaactgac cagcacttta tccccgcgaa gtcggtggat tggtcgctct ggcggcgcgg
    10141 tccccaaagt ggaccgtgga actacttcca accgcccgac ggtctgctgc cagaacaagg
    10201 atggaagatt cactgctccg ctacccaagc caacgcgcag gagctgctcg ataccgtttc
    10261 cgtgtattgc ggtcacaatc atgtgccgtt caaatttctt cggacggcag cagacctcat
    10321 gttgtccaac agcaagcagg ccaatcgaac ttccagcgga aaattcatca cgatctatcc
    10381 ggcggatggt gttgccacac aacgtgtcat caccgaactg gacaagcttg tcaccggtgc
    10441 cgacgggccg tacatcctca gcgatgtgcg atggaaccgg ggaccgctct acttacggta
    10501 cggcgcgtat ctgcccatgc agacctacga ttcattcggc gatcgcgtcc ccgcaattcg
    10561 gcgtcctgac ggatcgctcg aacccgatgt gcgcggcact tccttcagaa ctccggactg
    10621 ggtacaaatc ccggacttcg ttcgcgcgca gcaagacaag ctgaaatcac atgacgaatt
    10681 cccctattcg atcaatgaag ccctgcactt cagcaacagc ggggggatct actccgcgtt
    10741 cgacgacgcc ggcatcgatc tggtcatcaa agaaggccgt ccctttaccg ccccggacgc
    10801 caacggccgg tacgcaatcg accgcatccg taacgagtac gacaagttga cccaccttgc
    10861 cgacaacccg tacgcacctt ctgcgatcag gttgttcgag cgcgagggac accacttcct
    10921 tgtcaccgag cgcgctgccg gcactcccct gaatcaggaa gttgcgctcc gccacccact
    10981 gatacgcgcg gaccagacac tcagttcccg aacggaatac agaacctggg cactcgacat
    11041 tgcacaacag ttgactaccg cagtcgagag cttccacaac gccggaatcg ttcatgccga
    11101 tcttcaccct ggcaacgtca tgtgctcacc gtccggtatt cggatcatcg acttcgagat
    11161 ggcccacaac atcgacgagc atccgccccg gtccaccgga gcccccggat acacagcacc
    11221 tcgacagttg acaggaatcg cggcggatcg atactcgttg ggctgcatcg agctgggact
    11281 ctttgttcca cttactacat tgttccctct cgatcgcaac aagattcccg aactcatcga
    11341 ctatgcggtg tctcgattcg atcttccccg cgccttcggt gcctcgctct attcgatgct
    11401 cgacgtacag gcgccggcgc cgaagaatcg cccgcatcgt tgggacacgt cgtcgaacga
    11461 aaccttgcaa cgcacggccg ctctattgcg ctgcggcatc ctcgcctcgc ttgatctcgc
    11521 ccgcgctgat cgactctttc ccggcgacat cgcccagttc gaggtgaacg gctacggcat
    11581 tgcgcacggc tcgtgcggaa acctgctcgc cgatgtactt cccgcagaca ccttggagtc
    11641 agttctggaa tggactgaac atcaagttga ttcggatact caaccaaagt tcggcttctt
    11701 cgacgggctc gcgggtgcgg tgcatacctt tcggcatcac gggcgacatt cgacagccga
    11761 caggtgggtc gagactttgc gtcgagcccc actcgacgac atcgactcca gccttttcag
    11821 cggcctttcc ggaatcggtt gcctcctact cgaggaatcg gtttcacgac cgactgtgtc
    11881 acccactctc gctgtcgtga ccgagactct gcgcgaacga atttcagctg ctcgcttgca
    11941 tgtccgcgac gccggcggaa caccttgggc agtggccggc cgaggtgggc tgatgcgggg
    12001 accgagcgga caagcactgt tctggactcg ccactacgaa ctgagtggtg atcctcgatc
    12061 gctggaacac gcacgccagc tcgtcgacat cgatctgtct gtgatgtcga tgtgccctga
    12121 cgggtcgatg cagctgagag aggagcgccg gacgatgccg tatctcggat ccgggtctgt
    12181 cggtgtgggc ctggtacttc tacaacttct gcgccatgtc gacgaaccgc gttacgcagc
    12241 tgcggtgcgt gcgatatccc gcgccgccac agtcgaattc actgcccaag ccggactact
    12301 caacgggcga gccgggctga tgctgtttct cagcgaactc tccaagactc catacgccgg
    12361 cgccgattgt gaacagacgc ttgcacagca gtttcagctt ctgggcttgc acagcctcaa
    12421 tcacgcagga ggcctgcact ttccaggtga acagaacctg agactctcaa cagactgggc
    12481 aaccggatct gcaggaatac tggcgttgct cccatatacc ggatcggcaa ctgcccgaca
    12541 gtcgtttcca ctgatgtgcg cgtcgaactg ccacatcgcc taattgttcg gaagttatca
    12601 cccacggcag attggagcac agaagtacca ggcgaaaaac ctggaattaa atcaacaccg
    12661 caagcaaact cgatcgatca aatccatcgg caagaacgcc gatcaacaaa ggaaatgaca
    12721 atggacgcta ttctctccct tcaagatctg tcagtcgccg ccggcaacgt cggagacgca
    12781 ggccagctcg agcagaacgc ggcaatcagt tcgctcagtt tcttctgcct ctgacctcag
    12841 gccgatacct cggagcaagt ccggggtatc ggcttttaca atccatatcg aaaagaaaat
    12901 acgggtcgcc gcgtcgacta tcgacgaagc gacccgtatt gcaatgtcat tccgcgctga
    12961 acgagggaat catcatgctt cccatcactg ccaagccgct gacatctcga agcgaaccca
    13021 gagcattact caagaaagaa aaaagcatca gatactcacc tccttaagct gcgagttggc
    13081 ggatcggaag gtcatccctg cacccacccg tcgctcgaca atgcagtcag catctcgaag
    13141 aagctgacgt ggatcgctga cagtgacccg gtgaaaagac caaaaacatc ttccaaggaa
    13201 cccattttcg ccctccctaa tctatttgaa cggattgaac gggacgtcga ggccgaagtc
    13261 cacggagagc gcgaaaggca ttgtgatgat ggacttgaaa gcagtcagca tcatgggcaa
    13321 gagcgccgaa accgaaccca gatcagatga attcatctca catcctccta ttcgctcgag
    13381 attccgacga gtccgtcgat gacgactcca ccggcatcga ttgacccgta ggcgaaattc
    13441 agaatcgcct gcaagaacgg aactaacatt tcccactcct tcgcaacgga cattcgcatg
    13501 tcgtcggtac tattatccgt cgcccgtatt gcgggatctg gggccgagcg atcacgatgt
    13561 ggatgtaacc gtagacaaaa tcctagaaca tgtgccagtt tttgcgcttt atttcaaaga
    13621 tcccacctta agtaggatat tagacgattt actcataggt gaactcgtac ttaagtccta
    13681 cacaaaatgt cgaaatctgg cggttccgcg tggcaggccc attacagaat gaacggtatc
    13741 gtttcatcat ggaacgcatc cacacttcac cgagctgcat tcgccgatga tctacgcgac
    13801 ctggcggcaa tgccgagggc agatcgtatg gtcactggcg atgatattcc tcctgatcct
    13861 gacagccgca ctttcaggct ggttcgttca gcgttcgggc gagagttggg acttcggcga
    13921 catctgctca cgctggtacg acggaggtgg cagttgccgt gccgacaccg ctctcacctt
    13981 gacgacgctt ctcgtactcc tactaccgtt cgcctcagga atgctggtcg gcgtcaccac
    14041 attcgcccga gacttcgagc agggtcccga aaacctcgat tttctcgagt ccaccagcct
    14101 tgttcgatgg tatttcttgc gggtcctggt ggtcttcgtt cccatcaccc ttgcgatggc
    14161 agtcctgggc ctggtgctcg gctggaccca gacgcttggc cggggacagg cggcaacaaa
    14221 tgaggccacc tcgttttcct tgatggagtt ccccaatttt cagacgacgg gaatcgtcgt
    14281 cggcgcctac acctttttag caatgactac cggcagcgca gccgcattgc tcatccgcaa
    14341 caccgtcttc gcgatggtca tgactcttct cgcgttcttg atcgtgcccg tcgcactgag
    14401 cgcgacgatg cgcgagcatt acttggcccc cgacactgaa gtgcaaccca tcgacggact
    14461 ggcacgtgca gcggaatatg caccgtcgcc gtatgaaaat ctcgactcga ggtgggtcat
    14521 cgatgccggc ttcgccgata cggatggcaa catgatcgac gccgattaca caatgtgctg
    14581 gggctcagac aattccgatc gcaagcagca agacctcgag gtcgacaact gccttcgaga
    14641 acagggaatc gatcactatg ccgtgatcta tcacccacag agccggtact ggcaatttca
    14701 gttcatcgag actgccgtga tgctgttgtg ctccgggttg atggtggcgc tcgcactcgt
    14761 cggcgcacgt ggacgacgtc ggcgacccgc ctataaccga ctgtccgaaa tgtcgaaatc
    14821 gatttgatag cagcaatttt cgatccacct tctcttgtgt tcgaaacttt gttcgattat
    14881 gctttcggca tggacagtcg ggatgcgtgg cagctggatg gcgagggcct caagggggag
    14941 gttctggatc tggtgcgtgt ccggcacgag ttgcagtcgc ggttggtgtt gctgatcgtg
    15001 gagatgtttt cccgtgaggt tctcggcggg aagggttttc gggcgatcgc gcagtggttg
    15061 catggttcga cgaatttgga gatcggtgag tgcagtctgc tggtcgggtt ggcgcggttg
    15121 ttgatgctcg aacctgttgt cgcggatgcg tttcatcgcg gtgacgtgga tgcgttgaag
    15181 gcgcggcagg tggcgtcgtt ttgtcagcat ccgccgaaga acatgaccct ggcggatgtg
    15241 gacaaggctc gcgggatttt gttgtcgttg gcgtcgaaga acattgcgga ttgcgatgcg
    15301 gtgcgggcgg cgattcggcg gatcgagaag cagtacggca agcgcgagga cggcgttccg
    15361 gtcggcgagg attccgaacg taacgagttc tacgcgtcga aaggcttgta cgggcgggtc
    15421 actgtgaagg gtgatctgga tgcgatcaac ggggcccggt tgatcacgtt gttgtcgagc
    15481 ctgtcggctc cgacgccgga gaaggacggc gtgaaggaca cgcgtactcc ggcattacgg
    15541 cgtgcggacg ggttttgcga gttgttgcgc tggtacgagc gggcggggtt gggtccgatc
    15601 gagggcgggg tgaaaccgca catcacggtc accgcgtccg cgaaagacat gaccgacctt
    15661 aaagttctga aagacctgtt gccgtccacc gaggagctgg gatttgcgtg gacggattgg
    15721 gtgggcccga tcagcatcga caccgcccgg atgttggcgt gcgactgcac agtcacccgg
    15781 atcctcctgg atgagagtgg tgttccgctc gactgcggta aggaagcgag aacagcaacg
    15841 gtgccgcagc ggcgggcgtt gacggttcgt gatggccggt gtgcgtttcc ggggtgcggg
    15901 actccgtcgg ggtggtgcga tgcccatcat attgttcact ggaacgatgg tggcccaaca
    15961 gatctcgaca acctgatctt gttgtgcggt catcaccacc ggacgatgca ccacacggaa
    16021 tggcgggtgg agatcggacc ggatcgaaag acggtgttct atccaccgat gtcgatcgat
    16081 ccgtatcaac agccgatcgg cgggaacagc ccacccacag cggcgtgaat cgcgacaatc
    16141 gaatacatca gcgccgggga cgaaccatgc cccggtgctg gtgcacgttt ctggtcagat
    16201 cccaacccct caaatcccaa cccctcaaat cccagcccct cagatcccgg cccttcgcac
    16261 gagagcgtca gtggcagagg gggatacaac gtcaatcgct cgtaacagcc ccgcgtaccg
    16321 cggatacagc tcgacgggac gcgtattgat cgccctcaag atccacgatg cagcttgatc
    16381 ggccgtcagc gccggctggc tcacgtaatc cgccgtcgga gcgatcatcg gtgttcgtat
    16441 gagtgggaat tgcactgtgg tgacatcgac accggtgccg tgacattccg caccgaggct
    16501 tcggccgaat gcactgagag cagacttcga cgcgtgatag gcgctgaacc tgggcatcac
    16561 gcccgcagtg actccccagg ttccgacgtt gatgatgtgt ccggacttcg cctcgagcat
    16621 cgcgggcagt agccgcaacg tcagtcttga cggcccgaag tagttcagcg ccatggtgcg
    16681 ctcgtagtca tggaatcggt cgaccgaatc caacgcggta cgccggatcg agcgacccgc
    16741 attgttgacg aggatgtcga ccgacccgaa tcgatccgcg atcgtctccg cgagttcgtc
    16801 aacggcttca ccgcgggaga ggtccgcagg cacgatgtgt gcccatcctc ccctgcggtg
    16861 aatctcgtcc cgtacgtgtt cgaggttttc ctcaccgcgc gcgaccagga tcatctcggc
    16921 tccccgacga gccaaaagat gagctgtcgc ctcaccgatc cccgacgagg ctcccgtcag
    16981 gacgatggtc ttgtcggaaa gcgtgacgcc gcgagacaga acaagggagc gcagacgcgt
    17041 cggcggtctc aatgcaagat tgctgagaat cgatctgatc acgtcggcct cggttcgatc
    17101 ttcgcgtgcg attcggtgcg aacccgtccc tgaacagccc acttcggacg caccgcggaa
    17161 attactcaaa agtaagttat ggcgccgttt cggccgtgtc aagaattcgt cgggattcag
    17221 gagtatctgc cactagcttt tcctgatacc tcgggttaca ttaaatccag accgagtgcc
    17281 agcgatcaca caaccggccc tcgattccac cgaacaccgc gagaaatacc agcggtgacc
    17341 gaaacgaaga ggagacgcca tgacgctcac atcgccgctc gacaagcgcg gagaagcatc
    17401 cgacgactcg tacaacgaga cgcttcgact cctgtccgag ggctcggtgc acaagcactt
    17461 cgacccgtac ctcgacatcg actgggactc ccccgagttt gccgtcgtcc cgaacgatcg
    17521 ccgctggatc ctcccggccg agactgaccc gctgggtgca cacccgtggt accagtcgca
    17581 gtccgaggcc aggcagatcg aaatcggcat gtggcgccag gccaatgtcg cgaaggtcgg
    17641 tctccagttc gagaacattc tgatccgcgg catgatgcag tacgtcttct cactgcccaa
    17701 cgattcggcc gaggcgcgct actgcacgca cgagtcggtc gaagagtgca accacacgat
    17761 gatgttccag gagatggtca accgcatcgg tgccgacgct cccgggatga gccgtccgat
    17821 gaagatgctt gcacccttca tccccctcgc tgcgggtccg ttccccgaac tgttcttcgt
    17881 cggtgtcctc gccggtgaag agcccatcga ccacattcag aagagcatcc tgcgcgccgg
    17941 cggccagatc cacccgatca tgcagtcggt catggccatc cacgtagccg aggaagcgcg
    18001 tcatatctcg ttcgcgcaca agcttctgag ccgccgcatc ccgctgatgt cacgcccgaa
    18061 ccggtttgtc ctctcgctgc tgttcccgat cgtcatgcgc attctctgtg acgccatcgt
    18121 catcccgccg aagtccttct ggaagcagtt cgacatcccg aagtccgtga aaaaggacct
    18181 gttctgggat ctgcccgagt cgcgccagac cctgcgcaac tacttcggtg acgtccgcat
    18241 gctggccacc gacaccggcc tgatgaaccg tgcctcgcgc ctggtgtgga aggcctgcaa
    18301 gatggacggc cgcgcatcac gcttccgtag cgaacctcac cgcagctcgc acaacgccgc
    18361 cgcgtagctc ccggacagtc gagatcggac tcatagcgcc atgccacacg tagtcacgca
    18421 gtcctgttgc agcgacgcct cgtgcgtcta cgcctgcccg gtcaactgca tccatccgac
    18481 gccggacgag ccggacttcc tcaccgccga gatgctgcac atcgatccgc aggcctgcgt
    18541 cgactgtggc gcatgcgttt cggcctgccc ggtcgacgcc atcgtccccg agtcgaagct
    18601 gaccgacccg cagcgagtct tcctgtccat caatgcggac ttctacaagg aagagcgacc
    18661 caggccgctt ctcgccaagg tcatcccggc agcccacgtc gacaagggcc gaccgccgtt
    18721 gcgcgttgcg atcgtcggtt ccggaccgtc ggcgatgtac gccgcggacg agttgctgac
    18781 tcagcctgac gtgcaggtca atgtcttcga tcgccttcct gtgccttacg gcttggttcg
    18841 cgccggcgtt gctccggacc atcagaagac caagcaggtc actcgcttgt tcgacaagat
    18901 cgccgcacaa aagggtttcg agttctacct caacgtcgag atcggcaagc acatctcgca
    18961 cagcgaactg ctcgaaaatc accatgcggt gctctacgca gtcggcgctt cgtccgaccg
    19021 tggtctcggc attccgggcg ctgatctgcc tggcacggcc tcggccaccg acttcgtagc
    19081 ctggtacaac ggccaccccg atcacgccga cgacgtcttc gacctctcac atcgccgcgc
    19141 ggtcatcatc ggaaacggaa atgtcgcgct cgacgtcgct cgcattctga cggccgatcc
    19201 cgagaagttg gccggtaccg acatctccgc tcacgcactc gccgctctgc ggaagagtcg
    19261 cgtcgaagaa gttgtcatcg tgggtcgacg cggaatcgcg cagtccgcgt tcacggtccc
    19321 cgagttcacc ggcctgatgg cactgccgga catcgaactc tctgtcggac ccgacgacat
    19381 ggttctcgac tcggccaccg aagaactggc aaaacgcggc gaactcccgc atgccgtcga
    19441 gcagaagttg cgtctcctcg aagccctgaa gaaccgcgat cacgtcgacg tcggcaacaa
    19501 gcgcatcacg ttgcgctacc tgctcacgcc gacctcgatc accggcgacg atcaggtcag
    19561 cggaatcgag ttcgctcgca acgcacttgt cgacgcgaac ggaaccgtgc agatcgaagc
    19621 aaccggcgat accgagacca tcgataccgg cttggtcctc acctcgatcg gctaccgcgg
    19681 agtgcccatc cccggcgtcc cgttcgacga gcgtgcgtcg gtcattccga acgagaacgg
    19741 ccgagtcctc gaagctccga acggtgatcc cgccaccggg gtctacgcga ccggttggat
    19801 caaacgcgga ccgagtgggt tcatcggcac caacaagtcc tgcgcgcagg aaacgatcag
    19861 gatgctcgtc gacgacttca acgacggacg cctgaccaac ccggtcgccg acgactccgc
    19921 agtcgatcgt ctggtccggg cgcgacagtc cgacgtcgtc gaccgcgagg gctggcatgc
    19981 catcgacaag gcggaactgg aacgcggcgc tgcgcacgac cgtgtccgcg aaaaggttct
    20041 ggatcaggtc gagatcacct ccatcctcga cgctgcggcc cgggtgaaac cggcgcgtcg
    20101 attcggtcga cccgttcgcg ctcgctgatc cgctacaggt aaacagctac tttcacgcac
    20161 acggccccgc ctgcagactc gtctgcccgg cggggccgtc tgcgttccgg cagcgtccca
    20221 ctcagcgaaa atttttgccc gtcagcggcc gaaatcgtgt aatactgcaa cctgttccag
    20281 taagcggcac agcgggccca cgatcccccg gatcaggctc gccaaccaga tgaggattgc
    20341 atgagcgaga ctgcaacgcc ggcgccgaac gggagtgtga cgcctgcagt agagggttgg
    20401 ttcaccaccg gcgacgaacc tgctctgatc ggcacgaagt gccaatcctg cggcaccatt
    20461 tccttccctc gtgaggcgac gttctgcaag aacccgagct gcttcagcga ggagttcgac
    20521 gatgtggaac tctcccgtag cggcactgtc tggtcgtaca ccgacgcgca gtaccagccc
    20581 ccgccgccgt acatcccgcg ctcggatccg tacgagcctt ttgctctcgc agcagtcgaa
    20641 ctgcccgagg gcatcgtcat cctcggccag gtggccgacg gattcggcgt cgacgatctc
    20701 aaggtcggca ataccgtcga attggttgtc gagccgctgt acacggacga aaccggagta
    20761 cgtacgacgt ggcgctggaa gcctgtcgcc gccgatcagg agtcgcagtc atgagcaagg
    20821 acgtcgcagt actcggtgtc ggtatgcacc cctggggcaa gtgggggcag tcgttcgtga
    20881 aatacggcgt tgcggccgct cgcgccgcgc tcgccgattc gggtgtgaat tggcaggatg
    20941 tcgacttcat cgtcggcggc gagaccgtcc gcaacgggta cggcggatac gtcgccggag
    21001 ccaccttcgc gcaggcactc ggctggaacg gcgctcgcgt cgccacgtcg tacgccgcgt
    21061 gtgcgacggg agcccaggca ctcgacaccg ctcgcgcacg aatcctggcc ggcctcagcg
    21121 aagttgccct ggtcgtcggc gccgacacca cgccgaaggg cttcctcgct cccgtcgccg
    21181 gtgagcgttg ggacgacccg gactggctgc gcttccgcct catgggtatg accaacccgg
    21241 cgtacttcgc gctcaacgcg cgtcgtcgca tcgacctcta cggcgccacc gcggaggact
    21301 tcgccaacgt gaaggtcaag aacgccaagc acggactcaa taatccgaat gcgcgctacc
    21361 gcaaggaagt caccgtcgag aacgtgctgg catcccccgt ggtgtccaat cccctgcatt
    21421 tgctcgacat ctgcgcgacg tccgacggcg gcgccgcaat cttgctgacg tcgatggaat
    21481 acgcccgcaa gatgggcatc gcggaacctg ttcgcatcaa ggctatttcg acggtcacgc
    21541 cgacgttccc gcagacgatc atggatatgc cgaacttctc caccgattcc agctccgccg
    21601 tcccggctcc ggagcgcacg ttcaaggaat ccatcggcta cgccgcatac gaggaagccg
    21661 gaatctctcc cgaagacgtc gacatcgccg aggtctacga cctcgctacc tcggtggaac
    21721 tggactggat cgaagacctc gcgctgtgca agcggggcga ggccgagcac cttctgcgtg
    21781 cgggtgacac cagtatcgga ggccgcatcc cggtcaatcc gtccggtggt ctcgcgtgct
    21841 tcggcgaagc cgttcccgcg caggcacttg cgcaggtgtg cgagctcacc tggcagctgc
    21901 gcggacaagc cgaaggccgt caggtcgaag gcgcccgcat cggtatcacc gccaaccaag
    21961 gtctgttcgg acacggctcc tcggtaatcg tttccgcctg accctgttct actttcgtgg
    22021 cggtcgcaca ctcacccgtg agcggccgcc acgatcacgt ctgccactgc ccctggctgt
    22081 gagaccagcg aggcatggga ggtcgggagt tcgctggtgt tcgcgcccat ccggtttgcc
    22141 atgaaccgct gcgccgatgc ggggatcacg cgatcctcac cggcaaccag ataccagctc
    22201 ggtgtgttcg cccacgacgg tggcccgccg agctcgaggt tcgcccacaa agccgcagac
    22261 ttctgatgcg ccaacatcgt tgccgctgtc tcgtcggaaa catcctgagc gaagacggaa
    22321 tggaaatact cgtccgtgac gtagccgtcg acgttcttcc cgccgatcgc gtgaggatcg
    22381 tcgacgatct tcaatcccag agccggagga agcaattggc tgccaggaaa cctgatggga
    22441 tcgatcgtga tctgcaccgg ctcaccctga accggagcaa acgccgcgat gtacaccaac
    22501 gactgcacct tcgggtcgtg aacattggtg atcaccgcgc cgccgtaaga gtgtccgacg
    22561 agcacgacag gtccgtcgat gtc
//
