LOCUS       NZ_BBVA01000010        20966 bp    DNA     linear   CON 10-SEP-2024
DEFINITION  Micromonospora sp. NBRC 110037, whole genome shotgun sequence.
ACCESSION   NZ_BBVA01000010
VERSION     NZ_BBVA01000010.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Micromonospora sp. NBRC 110037
  ORGANISM  Micromonospora sp. NBRC 110037
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Igarashi,Y., Komaki,H., Ichikawa,N., Hosoyama,A. and Fujita,N.
  TITLE     Whole genome shotgun sequence of Micromonospora sp. NBRC 110037
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 262484)
  AUTHORS   Hosoyama,A., Ichikawa,N., Kimura,A., Ohshita,R. and Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-MAR-2015) Contact:Director-General Department Of
            Biotechnology National Institute of Technology and Evaluation,
            Biological Resource Center (NBRC); 2-49-10 Nishihara, Shibuya-ku,
            Tokyo 151-0066, Japan URL :http://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Noncontiguous Finished
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: newbler v. 2.6
            Genome Coverage                   :: 106x
            Sequencing Technology :: 454 GS-FLX Titanium; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001652995.1-RS_2024_09_10
            Annotation Date                   :: 09/10/2024 02:06:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,195
            CDSs (total)                      :: 6,136
            Genes (coding)                    :: 6,073
            CDSs (with protein)               :: 6,073
            Genes (RNA)                       :: 59
            rRNAs                             :: 1, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 15 of 63
            Pseudo Genes (incomplete)         :: 53 of 63
            Pseudo Genes (internal stop)      :: 4 of 63
            Pseudo Genes (multiple problems)  :: 9 of 63
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:59:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 131434
            Orig. end                         :: 152400
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBVA01000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20966
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20966
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20966
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10966](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10966)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            184..1521
                     /gene="hemL"
                     /locus_tag="A4R25_RS25975"
     CDS             184..1521
                     /EC_number="5.4.3.8"
                     /GO_function="GO:0042286 - glutamate-1-semialdehyde
                     2,1-aminomutase activity [Evidence IEA]"
                     /GO_process="GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (50-373). E-value: 2.6e-75.
                     Score: 245.5. Matches aSDomain:
                     nrpspksdomains_A4R25_RS25975_Aminotran_3.1"
                     /codon_start=1
                     /gene="hemL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012184519.1"
                     /locus_tag="A4R25_RS25975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="WP_064448400.1"
                     /sec_met_domain="Aminotran_3 (E-value: 4.9e-86, bitscore:
                     282.9, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9.5e-09, bitscore:
                     28.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETLSAGSGRYPADAPASEALFDRAKAVVPGGVNSPVRAFRAVG
                     GTPRFMVRGEGPWLFDADGRRYVDLVCSWGPLILGHAHPAVVEALREAATLGTSFGTPT
                     PGEVDLAEEIIARTPVEQVRLVNSGTEATMSAIRLARGFTGRSKIIKFAGCYHGHSDAL
                     LAAAGSGVATFGLPDSPGVTGAAAGDTIVLPYNDLRAVEEAFAAQGQHIAAIITEAAAG
                     NMGVIAPRDGFNAELARIAHAHGALLIVDEVMTGFRVSRAGWHGLDPSDADLWTYGKVM
                     GGGLPAAAFGGRAEIMAKLAPAGPVYQAGTLSGNPLACAAGLATLRLADDALYRRLDET
                     SAALGKLTTEALSAAGVPHRLSTAGNMFSVFFTDADVRDYDSARTQVVPAFKAFFHAML
                     TGGVYLPPSAFESWFVSTAIDDAAWEQIAAALPVAARAAAAAGSGG"
     aSDomain        334..1302
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R25_RS25975_Aminotran_3.1"
                     /evalue="2.60E-75"
                     /label="A4R25_RS25975_Aminotran_3.1"
                     /locus_tag="A4R25_RS25975"
                     /protein_end="373"
                     /protein_start="50"
                     /score="245.5"
                     /tool="antismash"
                     /translation="MVRGEGPWLFDADGRRYVDLVCSWGPLILGHAHPAVVEALREAAT
                     LGTSFGTPTPGEVDLAEEIIARTPVEQVRLVNSGTEATMSAIRLARGFTGRSKIIKFAG
                     CYHGHSDALLAAAGSGVATFGLPDSPGVTGAAAGDTIVLPYNDLRAVEEAFAAQGQHIA
                     AIITEAAAGNMGVIAPRDGFNAELARIAHAHGALLIVDEVMTGFRVSRAGWHGLDPSDA
                     DLWTYGKVMGGGLPAAAFGGRAEIMAKLAPAGPVYQAGTLSGNPLACAAGLATLRLADD
                     ALYRRLDETSAALGKLTTEALSAAGVPHRLSTAGNMFSVFFT"
     gene            1524..2171
                     /locus_tag="A4R25_RS25980"
     CDS             1524..2171
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454496.1"
                     /locus_tag="A4R25_RS25980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_013283542.1"
                     /transl_table=11
                     /translation="MAETVVHVLRHGEVHNPDGILYGRLPGFRLSELGVQMAKAAAQAL
                     ADRTVVHVVASPLERAQQTAEPIAAQFGLSVGVDERLIESANWFEGKKVSPGDGSFRDP
                     RNWWVLRDPVTPSWGEAYRAIAERMFAALHAARVAAEGREAVLVSHQLPIWTLRRHVER
                     KRLWHDPRRRQCGLASLTSFHFDGAKIVGIGYSEPAAHLVSISPTARTAKGA"
     gene            2171..2746
                     /locus_tag="A4R25_RS25985"
     CDS             2171..2746
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012184517.1"
                     /locus_tag="A4R25_RS25985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="WP_030500717.1"
                     /transl_table=11
                     /translation="MLTRRLAAALLAAVTAGTALVGCSSGSQESRCAADGSVVTCAPDQ
                     RSKTPKVSGELLTGGGYDISRDRGQVVVVNFWGSWCAPCRAEADDLEDTYQATKGSGVT
                     FLGINVQDSKDKALAFEEGRVTYPSIFDPASRQALNFDIPPNTTPATVVLDREGRIAVV
                     IRRAVTRDELRPIVEKIAAESPAPNGAR"
     gene            2746..3612
                     /locus_tag="A4R25_RS25990"
     CDS             2746..3612
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018821807.1"
                     /locus_tag="A4R25_RS25990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome c biogenesis CcdA family protein"
                     /protein_id="WP_064448401.1"
                     /transl_table=11
                     /translation="MGETFRQLAESGPLLFAVGAAALAGLVSFLSPCVLPLMPGYLSYV
                     TGLAGADLEGARKGPLLTPPVEEGPLVNSGGASGGGVGVAERAAPARTTAAVKGRVLAG
                     TLLFIAGFTVVFVATAILFSGVGKLFFRYERTLEIVIGALVVVLGLGYLGVIPGMQREF
                     RIRWLPSAGLLGAPVLGAVFALSWLPCTGPTLGAVLGMAATEGGTDRAVVLAVAYCLGL
                     GIPFVVFGLGFQRLLGVFRAVRRNSRWVTRIGGALLIAIGLALISGGWVNVVIWLQTNV
                     GVGEVSI"
     misc_feature    2929..2931
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3612..5231
                     /locus_tag="A4R25_RS25995"
     CDS             3612..5231
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283545.1"
                     /locus_tag="A4R25_RS25995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome c biogenesis protein ResB"
                     /protein_id="WP_064448402.1"
                     /transl_table=11
                     /translation="MTTVDDRPSTPPAQAPRRRVNPVLALLRNSWRQLTSMRTALILLF
                     LLAVAAIPGSVLPQRGVNPERVNQWFVDHPDLAPRLDQIGAFEVFGSVWFSAIYLLLFT
                     SLIGCILPRARDHVRALRMKPPAAPKRLERLPQHTVLEAPAAADPEAIAAVLRGRRWRV
                     TVRGNEVSAEKGYLKETGNLLFHVSLVAVLLGVALGSWYGWHGNRILVAGEDNAFCNTR
                     QQYAEASLGPRVDSADLPPFCLTLEKFEADYLPSGLASRYWATVTVEEPGGEARTAGFS
                     VNSPLRLGSANVYLLGNGYAPLLKYTDKYGRSQTSEAPFLRTGDSNATEEGVAIFPDAN
                     VDPKTGARAPDQQIAFDGLYLPTGPESAPYVASQYPSERNPMVNLTAYRGNLGMDAGIP
                     GSVYALDRRQIDDGKLKEIGTKLLRPGEKWTLDDGSTLEFVGTKPYITLAVRHAPGQTL
                     LLVASGTLLLGLMGSLFARRRRVWFRVLPPEGGSPTGGSSLVEAGGLPRTEHPGFADEF
                     AQLVAAVSGDAPDARRAREGDE"
     gene            5231..6196
                     /gene="ccsB"
                     /locus_tag="A4R25_RS26000"
     CDS             5231..6196
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /GO_process="GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ccsB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283546.1"
                     /locus_tag="A4R25_RS26000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="c-type cytochrome biogenesis protein CcsB"
                     /protein_id="WP_064448403.1"
                     /transl_table=11
                     /translation="MSALSDQLVAYAILVYLIAMISHAVEFALGNARKVPAAAPARELV
                     GAGVGGAGGTVDEPAAPPRPDHSAARAVLAGRIAGWLTAVAAAVHLGAVITRGVAADRM
                     PWGNMYEFVLTGTWIGVAAWLVVLWKQPWLRRLGLFLTLVMVLLLAFAELKLYVPIEPL
                     MPALQSWWFIIHVSTIIFASGLFLLGVVPAAAYLMRAGWEQGRRSFPYTLARRLPAAAG
                     LERLTFTLHAFSFPIFTFAVIAGAIWAEAAWGRAWGWDPKETWAFISWVVYAGYLHARA
                     TPSVKRNVATWISIVGFLTVMMNLFGVNFFFTGLHSYAGV"
     gene            complement(6165..6389)
                     /locus_tag="A4R25_RS26005"
     CDS             complement(6165..6389)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787858.1"
                     /locus_tag="A4R25_RS26005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_043327397.1"
                     /transl_table=11
                     /translation="MDDAYVVGDPDGLSPLQAEIRDAVARELHAQFALRADRLELADLP
                     EVAYQVTRRVDEVLSARPATTPRRTSADR"
     gene            complement(6434..6904)
                     /locus_tag="A4R25_RS26010"
     CDS             complement(6434..6904)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473525.1"
                     /locus_tag="A4R25_RS26010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_043327395.1"
                     /transl_table=11
                     /translation="MATPDRPGFALPLLLLAGFRTLVDDLHAELARQGHPELRPAHGFV
                     LQAVGPDGTTASDLGQRLGVSKQAAGKTVDRLVALGYLERVDDPTDARRKLVRTTAKGR
                     DGLHRSAAVFDELRDRWAATLGADRVAAIEDDLRRMVPADVFRLDVPGWFGG"
     misc_feature    6919..6934
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.98"
                     /tool="antismash"
     gene            6968..7522
                     /locus_tag="A4R25_RS26015"
     CDS             6968..7522
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283550.1"
                     /locus_tag="A4R25_RS26015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_064448404.1"
                     /transl_table=11
                     /translation="MSRFTTYEPDTAPAAARPVMAGVRRTLGHLPAAVGLMAGSPELLK
                     GFLAANAAFEATDLDPVAREVVVLAVATRNGCHLCVAMHTATLVRHAAAPELIEALRTG
                     ATLPDPRLEALRRFTVAVLDHRGAVPDADLDALLAAGWQRRHALDVVLGVGTYTISTFA
                     NRLTEAPLDAPLAAYAWTSAA"
     gene            7616..9076
                     /locus_tag="A4R25_RS26020"
     CDS             7616..9076
                     /GO_function="GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019901303.1"
                     /locus_tag="A4R25_RS26020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="menaquinone biosynthesis decarboxylase"
                     /protein_id="WP_043327390.1"
                     /transl_table=11
                     /translation="MAARGFPYTDLKDFLAALERAGELRRVSAPVDPTLEISEIVTRTV
                     RAGGPALLFERPTRGEMPVAINLFGTEKRMAMALGVEDLDEIGARIGDMLKPELPQGFS
                     GMMGGLGKVMQLKSMPPKKVKTAPCQQVVYRGDDVDLNRLPGLQVWPGDGGIFHNFGLT
                     HTKHPETGKRNLGLYRLQQHSHNTIGMHWQIHKNSTAHHAVAERLGERLPVAIAIGADP
                     VVAYSASAPLPADIDEYLFAGFLAGERVEMVDCLTVPLQVPAHAQIVLEGYIEPGERLP
                     EGPFGDHTGFYTPVEPFPVMHIECMTMQRDPVYHSIVTSQPPQEDHGLGKATERIFAPL
                     LRFLIPDIVDYDLPAAGVFHNCAIVSIRKRYPKHAQKVMNAIWGAHMMSLTKLIVIVDE
                     DCDVHDYNEVAFRAFGNVDYARDLLLTEGPVDHLDHASYQQFWGGKAGIDATRKLPEEG
                     YTRGWPEEMRMSPEVVSLVDKRWKEYGI"
     gene            9076..9981
                     /gene="mqnP"
                     /locus_tag="A4R25_RS26025"
     CDS             9076..9981
                     /codon_start=1
                     /gene="mqnP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787854.1"
                     /locus_tag="A4R25_RS26025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="menaquinone biosynthesis prenyltransferase MqnP"
                     /protein_id="WP_064448405.1"
                     /sec_met_domain="ubiA (E-value: 1.4e-93, bitscore: 307.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAVQERPGRVASFLKLVAIEHSVFALPFAYLSALTAMQLNGGR
                     VRWGDLLLITVAMVGARTFAMAANRILDRRIDARNPRTANRELVTGAVSVRTAWTGAAV
                     ALVVFLAAAALLNPLCLVLAPLAVVPLIVYPYGKRFTNWPHAILAVAQAVGPVGAWLAV
                     TGTLDGSGPAWLLGAAVGLWIGGFDLIYACQDSEIDREIGVHSVPARYGRRFALHASTV
                     AHAVTFALFIWFGAWVGFGWLWWIGLALTAAAFAYQHLVVSPTDLSKVNRAFFTANGFV
                     GIALFVLALLDLVIRLGLRP"
     gene            complement(10001..10966)
                     /locus_tag="A4R25_RS26030"
     CDS             complement(10001..10966)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283553.1"
                     /locus_tag="A4R25_RS26030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_064448406.1"
                     /sec_met_domain="T1TS (E-value: 6.7e-75, bitscore: 247.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAVLRALRSDCPITPRLSPYADDVQGWLVELVDRLGLPPDPAT
                     RRRLARAGFARYAGRLYPDATEADLRVLTALFTWFFLVDDACDGRDGLTPGQIRALRDG
                     ALALLREGPRARHPGFSGPLRRLLVQAWREPRRRMPARWRLRFADAVADHLDGVHREAT
                     ATGSGRPPGVAEYVRLRRATSAAYVSYPLIEFASGRPLPDAVYHHPALRRLADLANDLL
                     SWFNDIASLERDHATGGGHNLVLAVAAERGVPLPAAVDLVAGHWRAEMARFAALRAAAP
                     SFGPTLDDAVAVHLDGLAAAVRGTVDWTLESARYPVTPAS"
     gene            11112..11756
                     /locus_tag="A4R25_RS26035"
     CDS             11112..11756
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283554.1"
                     /locus_tag="A4R25_RS26035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="WP_043327384.1"
                     /sec_met_domain="Flavoprotein (E-value: 4.5e-23, bitscore:
                     75.6, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREPWVVGVSGASGTPYAAAVVRALLDAGQAVDLIVSRAARLTVL
                     DETGRPFRDGHWAEDLAAWLDRDLTGADIRHWPAGDLAAGPSSGSYRVRGMAVVPASTA
                     ACAGIAIGLSKDLLQRAAEVNLKERRPVVVVPRETPVTRSHLEHLIALHDAGAVVLPAS
                     PGFYGAGAAASAGQLVDFVAGKVLDALGVPHTLFRRWAGELASGRREPGPA"
     gene            complement(11814..12080)
                     /locus_tag="A4R25_RS26040"
     CDS             complement(11814..12080)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473529.1"
                     /locus_tag="A4R25_RS26040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="BldC family transcriptional regulator"
                     /protein_id="WP_013473529.1"
                     /transl_table=11
                     /translation="MDTGDRLLTPGEVAALFRVDPKTVTRWAAAGRIGSIRTPGGHRRF
                     RESEVRALLEGEGMLDEAEDMGKARNMGPTASTGPGPANAGMY"
     misc_feature    12169..12189
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.26"
                     /tool="antismash"
     misc_feature    12338..12351
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.03"
                     /tool="antismash"
     gene            12348..12806
                     /locus_tag="A4R25_RS26045"
     CDS             12348..12806
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012184509.1"
                     /locus_tag="A4R25_RS26045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_018787850.1"
                     /transl_table=11
                     /translation="MDTIDLSLVELLRGNARLSYAELARQVGLSAPAVHERVGKLESSG
                     VIRAYRAEVEPESIGLGVTALIGIIEDSDADTDDVLESFRRIPEIESCYFMAGVESFLL
                     KARVGTIAELEQLIVRLNRTAGVASTRTSIALSTKWENRPQPLEPPTA"
     gene            12849..13691
                     /locus_tag="A4R25_RS26050"
     CDS             12849..13691
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473530.1"
                     /locus_tag="A4R25_RS26050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_064448407.1"
                     /transl_table=11
                     /translation="MTISGRGAAVVTGAAGGLGRAIAVALHADGWNVLLTDVDADAVAA
                     AAAPLGGWSRPLDVRDESACADVAAEAAAAPGGLGLWVNNAGILVTGPSWAHDAPTRRA
                     VVEVNALGAMNGTLAAVAVMREQGRGHVLNVVSLAGLIAAPGETVYAASKHALLAFSLG
                     TLSDLRMAGVRGVHVSCLCPDGIWTPMLHDKLDDPGALASFTGSLLTPERVAARAVRLA
                     RRPRPVVSLPRWRGAQVRLLDAFPRLALALTPVIRATGRAGQRRQARRVRGNPSPPRL"
     gene            13702..14796
                     /locus_tag="A4R25_RS26055"
     CDS             13702..14796
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787848.1"
                     /locus_tag="A4R25_RS26055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="WP_064448408.1"
                     /sec_met_domain="PALP (E-value: 8.4e-48, bitscore: 157.2,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHLDRCDEASRRWVTEAIAAVEADANRSADTHLLPFPLPREWGI
                     DLYLKDESVHPTGSLKHRLARSLFLYGLCNGWIGPDTTIVEASSGSTAVSEAYFARMLG
                     LPFIAVMPASTSPEKIAQIEFQGGRCHLVQDPAKVVVEARWLAEDSGGRFMDQFTYAER
                     ATDWRGNNNIAESIYAQLALERHPVPAWIVVGAGTGGTSATIGRYARYRRLPTKLCVVD
                     PENSAFYPAWQAGDWSVCTGRGSRIEGIGRPTVEASFLPSVVDRMVQVPDAASLAAMRA
                     GSAVLGRRVGGSTGTNLWGAFGLIAQMLADGRTGSVVTLICDPGDRYVDTYYSDEWVAA
                     QGLDLAPHLATIDRFLTDGAWPAA"
     gene            complement(14813..15433)
                     /locus_tag="A4R25_RS26060"
     CDS             complement(14813..15433)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473532.1"
                     /locus_tag="A4R25_RS26060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="putative glycolipid-binding domain-containing
                     protein"
                     /protein_id="WP_043330730.1"
                     /transl_table=11
                     /translation="MPKSLFWARTDTAGCEHVVLDGGQGLTAQGVALAVDPIPYTCRYR
                     LALAPDWSTDQLEVEAEGAGWSRSVRLERGRDGWRVRTGEEGDLDAALSAAGHPPAGLP
                     GTDDPGRLDDALDVDLGGSPLTNTLPIRRIGLGRLPADMATAVTVAWVLLPGLAVVPAE
                     QVYTSLGPGRVRYASGTFTADLEVDPEGFVVRYPGLAERVDPR"
     gene            complement(15509..15718)
                     /locus_tag="A4R25_RS26065"
     CDS             complement(15509..15718)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283560.1"
                     /locus_tag="A4R25_RS26065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AlpA family transcriptional regulator"
                     /protein_id="WP_064448409.1"
                     /transl_table=11
                     /translation="MRRPRLYGPGELAALFGVSRQRVLQITRRPGFPEPLARLIGMNVW
                     DADEVDEWARHNRPSRPTEGDEQG"
     gene            complement(15753..15968)
                     /locus_tag="A4R25_RS26070"
     CDS             complement(15753..15968)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787846.1"
                     /locus_tag="A4R25_RS26070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AlpA family transcriptional regulator"
                     /protein_id="WP_064448410.1"
                     /transl_table=11
                     /translation="MGKETGPGELVAAGEILKMLGVGRSRFREIRRHPAFPAPYQELSV
                     GAVWLKRDVERYIREHRPPRPADDDE"
     gene            complement(16108..18009)
                     /locus_tag="A4R25_RS26075"
     CDS             complement(16108..18009)
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283563.1"
                     /locus_tag="A4R25_RS26075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_064448411.1"
                     /transl_table=11
                     /translation="MTTFAESSTSPSVDPNSDAVDFASLGLPRQLVEALARQGITTPFE
                     IQRATLPDSLAGRDVLGRGQTGSGKTLAFGLPVIARVADRNRARPLHPRALVLVPTREL
                     AMQVNDALVPLGKSVGVFLKTAVGGVPYDRQIDALRRGVEIVVATPGRLADLIERGVCR
                     LDDVEITVLDEADQMADMGFLPEVTQLLSKTPADAQRLLFSATLDNDVDTLVKRFMTDP
                     VTHSTAPATAAVSTMDHHLLLIPPHDKFAVAASIAAREGRTMLFARTQLGVDRLVEQLA
                     AVGVRAGGLHGGKTQRMRTKTLAEFREGRTPVLVATDVAARGIHVDGVSLVLHVDPPKD
                     PKDYLHRAGRTARAGESGAVATLVLPKQRRTTLAMMEKAGVEPAETRVRAGDEALAELT
                     GAREPSGVPVRDEPEPRRGGPRRFGDRDGRGFDRGGRGGFSDRGERRFGDRDGRGERRY
                     GDRPAGERSGDRFADRGGDRRFGDRPAGERYSGERAGGGERRFGRPERRDDRSFGDRRS
                     DGRSFGEQRSDDRGQRSDRFGGQRDDRRFGERADRPFGDRHRPAAGRGYDRDERRYDDR
                     PGGFGDRRQEDRPHAERRFGDRGDARPAERRSGGFRAEGRGRDDRRGFGGRPPARTH"
     misc_feature    complement(18006..18015)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.4"
                     /tool="antismash"
     gene            complement(18199..20160)
                     /locus_tag="A4R25_RS26080"
     CDS             complement(18199..20160)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473534.1"
                     /locus_tag="A4R25_RS26080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_064448412.1"
                     /transl_table=11
                     /translation="MGEHEVPAEKVHPGPTPDAADPADDSPAAARPGPVAVARARVTVA
                     GAAVPPPAGDEPPAAPSSPTTYRAGTPADAPPLDRRQPGATVPPSTWSAFAVAERPATP
                     EAPISTPAAGTPSPATPDGPAAGIPAPRVSGSARVPVPTPTALADSAAPAVPPAVSAPA
                     VSAPADSSTPAAPAGVSTPAGGETPGEDAAGADAVATDDRPDRDAAPGGPENAAGSTAT
                     DPRDGAPAAGSADSGTASPALAEQPAGPGAVPSAKPADLDAAPSAKPAGLNAALSTKPA
                     GQGGTAHARASAAVPGLSRVSADEIAASVVTAPAAATVYRAGPVNPEPPEPAQPPEPAQ
                     PPAPHGPEPEPAPTPVPGPTPPSPAPPVPEPEPPFRPTPPAPAPPAPAPTPPGPVPPVP
                     GPPVPPPGPAVPPPPPPPGPMPAPPFPPPPAMTAAANPLPAPLFPAPPATAGPSFGTPS
                     ATPGAPSFVTPPVTAGPPSFATPSAGSAVPPAPATTPFPSAPPATTGTPASSAESPPAW
                     AAAPVSAPPPPAVPAPALPTWPPPATPARDADATRPVRQQSGSTDLAGAVYGGGTDGPG
                     FATVSFPQGNPLENSGSLTGHILAQGWSEESPAARGGNTKVIIVLAVALTMLIAISLLV
                     VFLANDALSGLTGAMPVE"
ORIGIN
        1 ggtccgctgt acggcgatgg acagttcggc acgatccacc cggtcagcct atcgcgatct
       61 cgaccgacgg gcctgtcgag cggatcgctg gcggcctgcc gccgctcacc ggggtgagcc
      121 tggtaacccc cgtcgcgggg tgcgtgccag gcagtgctcc gacgctgaca caatgggccc
      181 atcgtgaccg agacgctttc cgccggatcc ggccgctacc cggccgacgc cccggcctcc
      241 gaggccctgt tcgaccgcgc caaggccgtc gtgcccggcg gggtgaactc tcccgtgcgc
      301 gcgttccgtg ccgtcggcgg caccccgcgc ttcatggtcc ggggggaggg tccgtggctc
      361 ttcgacgccg acggtcgtcg gtacgtcgac ctggtctgct cctggggccc gctcattctc
      421 ggccacgcgc acccggcagt ggtggaggcg ctgcgcgagg ccgccacgct gggcacgagc
      481 ttcggcacgc ccaccccggg tgaggtggac ctcgccgagg agatcatcgc gcggacgccg
      541 gtcgagcagg tgcgcctggt caactccggc accgaggcga ccatgtcggc gatccggctg
      601 gcccgcggct tcaccggccg ctccaaaatc atcaagttcg ccggctgcta ccacggccac
      661 tcggacgcgc tgctcgccgc cgccggctcc ggcgtggcca cgttcggcct gcccgactcg
      721 cccggcgtga ccggcgcggc agcgggcgac acgatcgtgc tgccgtacaa cgacctgcgc
      781 gcggtcgagg aggcgttcgc cgcccagggc cagcacatcg ccgcgatcat caccgaggcc
      841 gccgccggca acatgggcgt gatcgccccg cgcgacggct tcaacgccga actggcccgg
      901 atcgcgcacg cgcacggcgc gctgctcatc gtcgacgagg tgatgaccgg gttccgggtg
      961 tcccgcgccg gatggcacgg cctcgacccg tcggacgcgg acctgtggac gtacgggaag
     1021 gtcatgggtg gcggcctgcc cgccgcggcg ttcggcgggc gcgcggagat catggcgaag
     1081 ctcgccccgg ccggcccggt ctaccaggcc gggacgctct ccggtaaccc gctggcctgc
     1141 gccgccggac tggccacgct gcggctggcc gacgacgcgc tctaccggcg gctcgacgag
     1201 acctccgccg cgctcggcaa gctcaccacc gaggcgctgt ccgcggccgg cgtgccgcac
     1261 cgcctctcca ccgccggcaa catgttctcg gtcttcttca ccgacgcgga cgtgcgcgac
     1321 tacgacagcg cccgtaccca ggtggtgccg gcgttcaagg cgttcttcca cgcgatgctc
     1381 accggtggcg tctacctgcc gccgagcgcg ttcgagtcgt ggttcgtctc gaccgcgatc
     1441 gacgacgcgg cgtgggagca gatcgccgcc gccctgccgg tggcggcgcg ggcggcggca
     1501 gcggcgggaa gcggggggta actatggcgg agaccgtggt gcacgtgctg cggcacggtg
     1561 aggtgcacaa cccggacggc atcctctacg gccgcctgcc cgggttccgc ctctccgagc
     1621 tgggcgtgca gatggcgaag gcggccgcgc aggcgctcgc cgaccggacc gtggtgcacg
     1681 tggtggccag cccgctggag cgcgcccagc agaccgccga gccgatcgcg gcgcagttcg
     1741 gcctctccgt cggcgtcgac gagcggctga tcgagagcgc gaactggttc gagggcaaga
     1801 aggtctcgcc cggtgacggc tcgttccgcg acccgcgcaa ctggtgggtg ctgcgcgacc
     1861 cggtgacccc gtcctggggc gaggcgtacc gggccatcgc cgagcgcatg ttcgccgcgc
     1921 tgcacgccgc ccgcgtcgcc gccgagggcc gcgaggcggt gctcgtgtcg caccagctcc
     1981 cgatctggac gctgcgccgg cacgtcgagc gcaagcgcct ctggcacgac ccgcgccgcc
     2041 gccagtgcgg cctggccagc ctcacctcgt tccacttcga cggcgccaag atcgtcggca
     2101 tcgggtactc cgagccggcc gcccacctgg tgtcgatctc gccgaccgcc cggacggcca
     2161 agggggcctg atgctcaccc ggaggctcgc cgccgccctg ctcgccgccg tcaccgccgg
     2221 tacggcgctg gtcggctgct cctccggcag ccaggagagc cggtgcgcgg ccgacggctc
     2281 cgtcgtcacc tgcgcacccg accagcgctc gaagacgccg aaggtcagcg gtgagctgct
     2341 caccggcggc ggctacgaca tctcccgcga ccgcggccag gtcgtcgtgg tcaacttctg
     2401 gggctcctgg tgcgcgccct gccgtgccga ggcggacgac ctggaggaca cctaccaggc
     2461 cacgaagggc tccggcgtga cgttcctcgg catcaacgtg caggacagca aggacaaggc
     2521 gctcgccttc gaggagggcc gggtcacgta cccgagcatc ttcgacccgg ccagccggca
     2581 ggcgctcaac ttcgacatcc cgccgaacac caccccggcc accgtcgtgc tcgaccgcga
     2641 gggccggatc gccgtggtga tccgccgggc cgtcacccgc gacgagctgc gaccgatcgt
     2701 cgagaagatc gccgccgagt cgccggcgcc gaacggcgcc cgctgatggg cgagacgttc
     2761 cgccagctcg ccgagtccgg cccgctgctg ttcgcggtgg gcgcggccgc actggccggg
     2821 ctggtgagtt tcctgtcccc gtgcgtgctc ccgctgatgc ccggctacct gtcgtacgtg
     2881 accggcctgg ccggcgccga cctggagggt gcaaggaagg gccccctgtt aacgcctccg
     2941 gtagaggaag ggccccttgt taacagcggc ggcgcgagcg ggggcggtgt gggcgtcgcc
     3001 gagcgggcgg cgccggcccg gaccaccgcg gccgtcaagg gccgggtgct cgccggcacg
     3061 ctgctgttca tcgccggctt cacagtcgtg ttcgtcgcca ccgcgatcct cttctccggc
     3121 gtcggcaagc tcttcttccg gtacgagcgc acgctggaga tcgtcatcgg cgcgctcgtg
     3181 gtggtgctcg ggctcggcta cctcggggtg atccccggca tgcagcggga gttccggatc
     3241 cgctggctgc cctccgccgg gctgctcggc gcgccggtgc tcggcgcggt cttcgcgctc
     3301 agctggctgc cctgcaccgg cccgacgctc ggcgcggtgc tcggcatggc ggccaccgag
     3361 gggggcaccg accgggccgt ggtgctcgcc gtggcgtact gcctcgggct ggggataccg
     3421 ttcgtcgtct tcgggctggg cttccagcgc ctgctcgggg tgttccgcgc cgtccggcgc
     3481 aacagccgct gggtcacccg catcggcggg gccctgctga tcgcgatcgg cctggcgctg
     3541 atcagcggcg gctgggtgaa cgtggtgatc tggctgcaga cgaacgtggg cgtgggcgag
     3601 gtgagcatct gatgacgacc gtcgacgacc ggccgtcgac ccctccggcg caggcgcccc
     3661 gacggcgggt caacccggtg ctggccctgc tgcgcaactc gtggcggcag ctcaccagca
     3721 tgcgtaccgc gctgatcctg ctgttcctgc tcgccgtcgc ggccatcccc ggctcggtgc
     3781 tgccgcagcg cggcgtcaac ccggaacggg tcaaccagtg gttcgtggac caccccgacc
     3841 tcgcgccccg gctggaccag atcggcgcgt tcgaggtctt cggctcggtc tggttctccg
     3901 cgatctacct gctgctgttc acctcgctga tcggctgcat cctgccccgc gcccgggacc
     3961 acgtccgcgc gctgcggatg aagccgccgg ccgcgccgaa gcggctcgaa cggctgcccc
     4021 agcacacggt gctggaggcc ccggccgccg ccgaccccga ggcgatcgcg gcggtgctgc
     4081 gcggccgccg gtggcgggtc accgtgcgcg gcaacgaggt ctccgccgag aagggctacc
     4141 tcaaggagac cggcaacctg ctcttccacg tgtcgctggt cgccgtcctg ctcggggtcg
     4201 cgctcggttc ctggtacgga tggcacggca accgcatcct ggtcgcgggc gaggacaacg
     4261 ccttctgcaa cacccgtcag cagtacgccg aggcgtcgct cggcccgcgc gtggacagcg
     4321 ccgacctgcc gccgttctgc ctgacgctgg agaagttcga ggccgactac ctgccgtccg
     4381 ggctggcgtc ccgctactgg gccacggtga ccgtggagga gccgggcggc gaggcgcgga
     4441 ccgccggctt ctcggtcaac tcgccgctgc ggctcggctc ggcgaacgtc tacctgctcg
     4501 gcaacggcta cgcgccgctg ctgaagtaca ccgacaagta cggccgcagc cagaccagcg
     4561 aggcgccgtt cctgcgtacc ggcgactcca acgcgaccga ggagggcgtg gcgatcttcc
     4621 cggacgccaa cgtcgacccg aagaccggcg cgcgggcccc ggaccagcag atcgccttcg
     4681 acgggctcta cctgcccacc gggccggaga gcgcgccgta cgtggcgtcg cagtatccgt
     4741 ccgagcgcaa cccgatggtg aacctgaccg cgtaccgggg gaacctcggg atggacgccg
     4801 gcatccccgg ctcggtctac gcgctggacc ggcggcagat cgacgacggc aagctcaagg
     4861 agatcggcac caagctgctg cggccggggg agaagtggac cctcgacgac ggcagcacgc
     4921 tggagttcgt cggcaccaag ccgtacatca cgctcgcggt ccggcacgcg cccgggcaga
     4981 cgctgctgct ggtggccagc ggcacgctgc tgctgggcct gatgggctcg ctgttcgccc
     5041 ggcggcgacg ggtgtggttc cgggttttgc ccccggaggg tggatctccg acgggcggta
     5101 gtagtttggt ggaggccggt gggctgccgc gcaccgagca cccagggttc gccgacgagt
     5161 tcgcgcagct cgtcgccgcg gtgagcggcg acgcgccgga cgcgcggcgg gcgcgagaag
     5221 gagacgagtg atgtccgcac tctccgacca gctggtcgcg tacgcgatcc tggtgtacct
     5281 gatcgcgatg atcagccacg ccgtggagtt cgcgctgggc aacgcgcgga aggtccccgc
     5341 ggccgcgccc gcgcgggaac tggtcggcgc gggcgtcggc ggcgccggcg gcaccgtcga
     5401 cgagccggcc gcgccgccgc ggccggacca ctccgccgcc cgggccgtgc tggccggccg
     5461 gatcgccggc tggctcaccg cggtcgccgc cgccgtgcac ctgggcgcgg tgatcacgcg
     5521 gggcgtcgcc gccgaccgga tgccctgggg caacatgtac gagttcgtgc tgaccggcac
     5581 ctggatcggt gtggcggcct ggctcgtggt gctctggaag cagccgtggc tgcgccggct
     5641 cgggctgttc ctgacgctgg tgatggtgct gctgctggcg ttcgccgagc tgaagctcta
     5701 cgtgccgatc gagccgctga tgccggcgct gcagtcgtgg tggttcatca tccacgtctc
     5761 gacgatcatc tttgcctcgg gcctcttcct gctgggcgtg gtgcccgccg ccgcgtacct
     5821 gatgcgggcc ggctgggagc agggtcgccg cagcttcccg tacaccctgg cccgccgcct
     5881 tccggcggcg gccgggctgg agcggttgac cttcacgctg cacgccttct cgttcccgat
     5941 cttcacgttc gcggtgatcg cgggcgcgat ctgggccgag gcggcgtggg gccgcgcctg
     6001 gggctgggac cccaaggaga cctgggcgtt catctcctgg gtggtgtacg cgggctacct
     6061 gcacgcccgg gccacgccga gcgtgaagcg caacgtggcg acctggatct ccatcgtggg
     6121 cttcctgacc gtgatgatga acctgttcgg cgtgaacttc ttcttcaccg gtctgcactc
     6181 gtacgccggg gtgtagtggc cgggcgcgcg ctcagcacct cgtccacccg gcgcgtgacc
     6241 tggtaggcca cctccggcag gtcggccagt tcgaggcggt cggcccggag cgcgaactgg
     6301 gcgtgcagtt cgcgggccac cgcgtcgcgg atctctgcct ggagtgggct gaggccgtcc
     6361 gggtcaccca ccacgtatgc gtcgtccatc cgccgatgat gaaccgccgt cggcgatcct
     6421 gtcagtgacg aattcatccg ccgaaccagc cggggacgtc gaggcggaac acgtcggcgg
     6481 gaaccatccg gcgcaggtcg tcctcgatgg cggcgacccg gtccgcgccg agcgtggccg
     6541 cccagcggtc gcgtagctcg tcgaagaccg ccgccgagcg gtgcagcccg tcgcggccct
     6601 tcgcggtcgt ccggaccagc ttgcgtcggg cgtcggtcgg gtcgtccacg cgttccaggt
     6661 agccgagcgc gaccagccgg tccaccgtct tgcccgctgc ctgcttggag acgccgagac
     6721 gctggccgag gtcggaggcg gtggtgccgt ccgggccgac ggcctggagg acgaacccgt
     6781 gggccgggcg cagctcgggg tgcccctggc gggccagctc ggcgtgcagg tcgtcgacga
     6841 gcgtacggaa gccggcgagc aggagcagcg gcagcgcgaa gccggggcgg tcaggcgttg
     6901 ccacgttcga caaccacgtt tactatttcg tcaaccacgt tgaccatctt acgagagggg
     6961 cacagtcatg tcccgcttca ccacgtacga gccggacacc gcacccgccg ccgcccgccc
     7021 ggtcatggcc ggggtacgcc gcacactggg ccacctgccc gctgccgtcg gcctgatggc
     7081 gggctcaccc gaactattga agggcttcct cgccgccaac gccgcgttcg aggcgaccga
     7141 cctcgacccg gtcgcccggg aggtggtcgt gctcgccgtc gccacccgca acggctgcca
     7201 cctctgcgtg gccatgcaca ccgctacgct cgtccggcac gccgccgcgc cggagctgat
     7261 cgaggcgctg cggaccggcg cgacgctgcc cgaccctcgg ctggaggcgc tgcgccggtt
     7321 caccgtcgcc gtcctcgacc accggggcgc ggtccccgac gccgacctcg acgcgctgct
     7381 cgccgccggg tggcagcgcc ggcacgcgct ggacgtggtg ctcggcgtcg gcacgtacac
     7441 catctccacg ttcgccaacc ggctcaccga ggcgccgctc gacgcgccgc tggccgcgta
     7501 cgcctggacg tccgcggcct gagctgcggg gtgttaagaa ggggcccctc ctctacggga
     7561 ggcgttaaca gggggccctt ccttacctcc caggaacgtg cgggaggatg gcggcatggc
     7621 ggctcgtggc ttcccgtaca ccgatctcaa ggacttcctc gcggcgctgg agcgcgcggg
     7681 cgagctgcgg cgggtgagcg cgccggtcga ccccacgctg gagatcagcg agatcgtcac
     7741 ccgcaccgtc cgggccggcg ggccggcgct gctgttcgag cgccccaccc ggggtgagat
     7801 gccggtggcg atcaacctgt tcggcaccga gaagcggatg gcgatggcgc tcggggtgga
     7861 agacctcgac gagatcggcg cgcggatcgg cgacatgctc aagccggagc tgccgcaggg
     7921 cttctccggg atgatgggtg gcctcggcaa ggtcatgcag ctcaagtcga tgccgccgaa
     7981 gaaggtcaag accgccccct gccagcaggt cgtctaccgg ggcgacgacg tcgacctgaa
     8041 ccggctgccc gggttgcagg tgtggcccgg cgacggcggg atcttccaca acttcgggct
     8101 gacccacacc aagcacccgg agaccggcaa gcgcaacctc gggctctacc ggctccagca
     8161 gcacagccac aacacgatcg gcatgcactg gcagatccac aagaactcca ccgcgcacca
     8221 cgcggtcgcg gagcggctgg gcgagcggct gccggtggcg atcgccatcg gcgcggaccc
     8281 ggtggtggcg tactcggcca gcgcgccgct gcccgccgac atcgacgagt acctgttcgc
     8341 cgggttcctc gccggtgagc gggtcgagat ggtcgactgc ctgaccgtcc cgctccaggt
     8401 gccggcgcac gcgcagatcg tgctggaggg ctacatcgag ccgggcgagc ggctgcccga
     8461 gggcccgttc ggcgaccaca ccggcttcta cacgccggtc gagccgttcc cggtgatgca
     8521 catcgagtgc atgaccatgc agcgcgaccc ggtctaccac tcgatcgtca cgtcccagcc
     8581 gccgcaggag gaccacggtc tcggcaaggc caccgagcgg atcttcgcgc cgttgctgcg
     8641 cttcctgatc ccggacatcg tcgactacga cctgcccgcc gccggtgtct tccacaactg
     8701 cgcgatcgtg tcgatccgca agcgctaccc gaagcacgcg cagaaggtca tgaacgcgat
     8761 ctggggcgcg cacatgatgt cgctgaccaa gctgatcgtg atcgtggacg aggactgcga
     8821 cgtccacgac tacaacgagg tcgcgttccg cgccttcggc aacgtcgact acgcccgtga
     8881 cctgctcctc accgagggcc cggtggacca cctcgaccac gcctcgtacc agcagttctg
     8941 gggcggcaag gcgggcatcg acgcgacccg caagctgccc gaggagggct acacccgggg
     9001 ctggccggag gagatgcgga tgtcgcccga ggtggtctca ctggtggaca agcgctggaa
     9061 ggaatacggg atctgatgac ggcggcggta caggaacggc ccggccgggt cgcgtccttc
     9121 ctcaagctcg tcgccatcga gcactcggtc ttcgcgctgc cgttcgcgta cctgtcggcg
     9181 ctgaccgcca tgcagctcaa cggcggccgg gtgcgctggg gcgacctgct gctgatcacc
     9241 gtggcgatgg tcggcgcgcg gacgttcgcc atggccgcga accgcatcct cgaccggcgg
     9301 atcgacgcgc ggaacccgcg tacggcgaac cgggaactgg tcaccggcgc ggtgagcgtg
     9361 cggacggcct ggaccggcgc ggccgtcgcg ctcgtggtgt tcctggccgc cgccgccctg
     9421 ctcaacccgc tctgcctggt gctcgcgccg ctggccgtgg tgccgctgat cgtctacccg
     9481 tacggcaagc ggttcaccaa ctggccgcac gccatcctcg cggtggcgca ggcggtcggc
     9541 ccggtcggcg cctggctggc ggtcaccggc acgctcgacg gctccggccc ggcctggctg
     9601 ctcggcgcgg cggtcggcct ctggatcggc ggcttcgacc tgatctacgc ctgccaggac
     9661 tcggagatcg accgggagat cggcgtgcac agcgtccccg cccggtacgg ccggcgcttc
     9721 gcgctgcacg cctccaccgt cgcgcacgcg gtgacgttcg cgctgttcat ctggttcggc
     9781 gcgtgggtcg gcttcggctg gctgtggtgg atcgggctgg cgctgaccgc tgccgccttc
     9841 gcgtaccagc acctggtggt cagcccgacc gacctgagca aggtcaaccg ggcgttcttc
     9901 accgcgaacg gcttcgtcgg catcgcgttg ttcgtcctcg cgctgctcga cctggtgatc
     9961 cggctcggcc tgcggccgta acggcaacgc cggaacgcgg tcaggacgcc ggggtgaccg
    10021 gatagcgggc gctctccagc gtccagtcca cggtgccgcg cacggcggcg gccaggccgt
    10081 cgaggtggac ggcgacggcg tcgtcgagcg tcgggccgaa cgacggcgcc gccgcgcgga
    10141 gcgccgcgaa ccgggccatc tcggctcgcc agtgcccggc caccaggtcg accgccgccg
    10201 gcagcggcac gccccgctcg gcggccactg ccagcaccag gttgtgcccg ccgccggtgg
    10261 cgtggtcgcg ctccagcgag gcgatgtcgt tgaaccagga cagcaggtcg ttcgcgaggt
    10321 ccgcgagccg ccgcagtgcc gggtggtggt agaccgcgtc gggcagcggg cgtccggacg
    10381 cgaactcgat gagcgggtac gacacgtacg ccgccgaggt ggcccggcgc agccgcacgt
    10441 actcggcgac gcccggcgga cggcccgacc cggtggcggt ggcctcccgg tggacgccgt
    10501 cgaggtggtc ggcgaccgcg tcggcgaaac gtagccgcca gcgggccggc atccggcggc
    10561 ggggctcccg ccacgcctgc accaacaggc ggcgcagcgg gccggagaag cccggatggc
    10621 gggctcgcgg accctcgcgc agcaacgcga gcgcgccgtc gcgcaacgcg cggatctgcc
    10681 ccggcgtcag cccgtcccgc ccgtcgcagg cgtcgtcgac caggaagaac caggtgaaca
    10741 gcgcggtcag cacccgcagg tccgcctcgg tggcgtccgg gtagaggcgg ccggcgtacc
    10801 gggcgaaccc ggcccgcgcc agccgccgcc gggtggccgg gtcgggcggc agaccgagcc
    10861 ggtcgaccag ttccaccagc cagccctgca cgtcgtccgc gtacggggag aggcggggcg
    10921 tgatggggca gtcggagcgc agcgcccgca gcaccgccgc agtcatcacc ggcccttccc
    10981 acggaagtgg atttgccgat cgaagaattt cacgccgagg gaactcccgt gaaccctctg
    11041 gacatcccgg gcgggccgcc cgaacggggg tcgtggtccg ccgcccgcgg cgaccaggca
    11101 cgcttgaggg catgcgcgaa ccatgggtgg tgggtgtctc cggcgcctcg ggcacgccgt
    11161 acgcggcggc ggtcgtccgg gcactgctcg acgcgggcca ggcggtggac ctgatcgtgt
    11221 cccgggcggc ccggctgaca gtgctggacg agaccggccg gcccttccgg gacgggcact
    11281 gggccgagga cctggccgcc tggctcgacc gcgacctcac cggcgcggac atccggcact
    11341 ggcccgccgg tgacctggcc gccggcccga gcagcggctc ctatcgggta cgcgggatgg
    11401 cggtggtgcc ggccagcacc gccgcctgcg ccggcatcgc catcgggctc tccaaggacc
    11461 tgctccagcg tgccgccgag gtgaacctca aggagcgccg cccggtagtg gtggtgcccc
    11521 gggagacccc ggtgacccgc agccacctgg agcacctcat cgcgctgcac gacgcgggcg
    11581 ccgtggtgct gccggccagc ccgggcttct acggcgccgg ggcggcggcc tccgccgggc
    11641 agctcgtgga cttcgtggcc ggcaaggtgc tggacgcgct gggcgtcccg cacacgctgt
    11701 tccgccggtg ggccggtgag ctggcctccg gtcgccggga gcccggcccg gcctgaccgg
    11761 acccggcgta cgacgagcgg ggcgcggcct cgatcggacc gcgccccgca cgttcagtac
    11821 atgccggcgt tcgccgggcc ggggccggtg gaagcggtcg ggcccatgtt gcgggccttg
    11881 cccatgtcct ccgcctcgtc cagcatgccc tccccctcga gcagggcccg cacctcggat
    11941 tcccgaaacc ggcggtgccc tcctggagtc cggatactgc cgatccggcc ggccgctgcc
    12001 catctggtca cggttttcgg gtcaacccga aacagcgcag cgacctcacc cggtgtcagc
    12061 aggcgatctc cagtgtccac agccccctcc tcgcgtcgac gaagcccccg gctgaacaca
    12121 ctgcccccgg ccggtgcgag cccagagccg tcatgaggga cgtatggcaa ttacagcacc
    12181 ggctaccgga cgtgtccgcc aaacgcgaaa aacgcacaca ctgggaagtt aggaaatggt
    12241 accggcggag aacccccgtg agcgcacgtt tgtgataggc gcggcccgac ctcatcgtcg
    12301 cccggtggcc gcagtgccgg gccccgatcg agatagggtc actctccgtg gacacgatcg
    12361 acctgagcct tgtggagctg ttgcgaggca acgcccgtct gtcgtacgcc gagctggccc
    12421 gtcaggtcgg cctctccgcc ccggccgtgc acgagcgggt cggcaagctg gagtccagcg
    12481 gcgtgatccg ggcgtaccgg gccgaggtcg agccggagtc gatcgggctc ggcgtcaccg
    12541 cgctcatcgg catcatcgag gactccgacg cggacaccga cgacgtgctg gagtcgttcc
    12601 ggcgcatccc cgagatcgag tcctgctact tcatggccgg cgtcgagtcc ttcctgctca
    12661 aggcgcgggt cggcacgatc gccgagctgg agcagctgat cgtccggctg aaccggacgg
    12721 ccggcgtggc atccacccgt accagcatcg ccctgtcgac caagtgggag aaccgcccgc
    12781 agccgctgga accgcccacc gcctgatcac tctggccccg gcgcggggat tgcggttacc
    12841 gtgcgccgat gacgatctcg ggacgcggcg ccgcagtggt caccggtgcg gccggcgggc
    12901 tgggccgggc catcgccgtc gcgctgcacg ccgacggctg gaacgtgctg ctcaccgacg
    12961 tcgacgccga tgccgtggcg gccgccgccg cgccgctggg tggctggtcg cgcccgctcg
    13021 acgtacgcga cgaatccgcc tgcgcggacg tggccgccga ggcggcggcc gcacccggcg
    13081 gcctcgggct ctgggtgaac aacgcgggca tcctggtcac cggcccgtcc tgggcgcacg
    13141 acgccccgac ccggcgcgcg gtggtcgagg tgaacgcgct cggcgcgatg aacggcacgc
    13201 tcgccgccgt cgcggtgatg cgcgagcagg gccgcggcca cgtgctgaac gtcgtctcgc
    13261 tggccgggct gatcgccgcg ccaggcgaga cggtgtacgc ggccagcaag cacgccctgc
    13321 tcgcgttcag cctcggcacg ttgagcgacc tgcggatggc cggcgtccgg ggcgtacacg
    13381 tgtcgtgcct gtgcccggac gggatctgga cgccgatgct gcacgacaag ctggacgacc
    13441 cgggcgcgct ggcatccttc accggttcgc tgctgacgcc ggagcgggtg gccgcgcggg
    13501 ccgtccggct ggcccggcgg ccccggccgg tggtcagcct gccgcgctgg cgcggcgccc
    13561 aggtacggct gctcgacgcc ttcccccggc tcgccctggc gctcacgccg gtgatccggg
    13621 ccaccggccg ggccggtcaa cggcggcagg cccgccgggt ccggggaaac ccgagcccac
    13681 ctcgcttgta acgttgccga cgtgactcat ctcgaccggt gcgacgaggc cagccggcgc
    13741 tgggtgaccg aggcgatcgc cgctgtcgag gcggacgcca accgctccgc cgacacccac
    13801 ctgctgccgt tcccgctgcc ccgcgagtgg gggatcgacc tctacctcaa ggacgagtcg
    13861 gtgcacccca ccggctcgct caagcaccgg ctcgcccgct cgctgttcct ctacgggctc
    13921 tgcaacggct ggatcggccc ggacaccacg atcgtcgagg cgtcgtccgg ctcgacggcg
    13981 gtctccgagg cgtacttcgc gcggatgctc gggctgccgt tcatcgcggt catgcccgcc
    14041 tccacgtcac cggagaagat cgcccagatc gagttccagg gcgggcgctg ccacctcgtc
    14101 caggacccgg cgaaggtggt ggtggaggcg cgctggctcg ccgaggacag cggcggccgg
    14161 ttcatggacc agttcacgta cgccgagcgg gccaccgact ggcggggcaa caacaacatc
    14221 gccgagtcga tctacgccca gctcgcgctg gaacggcacc cggtgcccgc ctggatcgtc
    14281 gtcggcgccg gcaccggcgg caccagcgcc accatcggcc gctacgcccg ctaccggcgg
    14341 ctgcccacca agctctgcgt ggtggacccg gagaactccg cgttctaccc cgcctggcag
    14401 gccggcgact ggtcggtgtg caccggccgc ggctcccgga tcgaaggcat cgggcggccc
    14461 acagtcgagg cgtccttcct gcccagcgtg gtggaccgga tggtgcaggt cccggacgcc
    14521 gcgtcgctcg ccgccatgcg ggccggctcg gcggtgctcg gccgccgcgt gggcggctcc
    14581 accggcacca acctgtgggg cgcgttcggg ctgatcgccc agatgctcgc ggacggacgt
    14641 accggctcgg tggtcacgct catctgcgac ccgggcgaca ggtacgtcga cacctactac
    14701 tccgacgagt gggtggccgc gcagggcctc gacctcgccc cgcacctggc caccatcgac
    14761 cggttcctga ccgacggcgc ctggccggcg gcctgagccg gcccccggac tgtcagcgcg
    14821 ggtcgacccg ctcggccagc cccggatagc gcaccacgaa accctccggg tcgacctcca
    14881 ggtcggccgt gaacgtgccg ctggcgtacc ggacccggcc cgggccgagc gaggtgtaga
    14941 cctgctcggc ggggaccacg gccaggccgg gcagcagcac ccaggccacg gtcaccgccg
    15001 tcgccatgtc ggcgggcagc cgccccaacc cgatccggcg gatcggcagc gtgttcgtca
    15061 gcggggaccc gcccaggtcg acgtcgagcg cgtcgtccag ccggcccggg tcgtcggtgc
    15121 ccggcaaccc cgccggtggg tggcccgccg cgctcagcgc cgcgtccagg tcgccctcct
    15181 cgccggtacg cacgcgccac ccgtcccggc cccgttccag gcgtacgctc cgcgaccagc
    15241 cggcgccctc tgcctcgacc tccagctggt cggtcgacca gtcgggcgcg agcgccaggc
    15301 ggtaacggca ggtgtacggg atcgggtcca cggcgagtgc cacgccctgc gcggtcagcc
    15361 cctgcccgcc gtcgagcacg acgtgctcgc agccggcggt gtcggtccgg gcccagaaga
    15421 gcgacttcgg catggtccgg acgttacgcg acccggccgt cggcggcagc ggatgcgcga
    15481 acgccgccgc cggccggatg gccactgact acccctgctc gtcgccctca gtggggcgcg
    15541 acggccggtt gtggcgggcc cactcgtcga cctcgtccgc gtcccagacg ttcatgccga
    15601 tcagccgggc gagcggctcg gggaacccgg ggcggcgggt gatctgcagg acccgctgac
    15661 gcgatacgcc gaacagggcg gccaactcgc cgggcccgta caggcgtggt cgtctcaccc
    15721 gacgaaggta gtcatggtcg tgcctcttcg ggctattcgt cgtcgtccgc cggccggggc
    15781 ggccggtgct cccggatgta ccgctccacg tcccgcttca gccagacggc gccgaccgac
    15841 agctcttgat acggcgcggg gaatgcggga tgccgccgga tctcgcggaa tctcgatctg
    15901 cccacgccga gcatcttcaa gatctcaccg gccgcgacga gttcgcccgg tcccgtctcc
    15961 ttgcccatga cttcgaaggt agggaacgag ccgacccggc gacatcccgt cctcacgccg
    16021 cgcacctaga acgggagccg aaatcaccac agacgcacag ccgccgccga gcgggtgctc
    16081 ggcggcggcg tcgtgggtgc gctcagatca gtgggtacgc gccggcggtc gcccgccgaa
    16141 gccgcgccgg tcgtcccggc cccgcccctc ggcccggaaa ccgccgctcc ggcgctcggc
    16201 cggacgcgcg tcgccccggt caccgaaacg ccgctcggcg tgcgggcggt cctcctggcg
    16261 acggtcaccg aagccacccg gccggtcgtc gtaccgccgc tcgtcgcggt cgtacccgcg
    16321 cccggccgcc ggccggtgcc ggtccccgaa cgggcggtcg gcgcgctcgc cgaaacgcct
    16381 gtcgtcgcgc tggccgccga agcggtcgct gcgctggcca cggtcgtcgg accgctgctc
    16441 gccgaagctc cggccgtcgg accgccggtc gccgaagctc cggtcgtcgc gacgctccgg
    16501 ccgcccgaag cggcgctcgc cgccaccggc ccgctcgccc gagtagcgct cgcccgccgg
    16561 acggtcgccg aaccggcggt caccgccacg gtccgcgaac cggtcgccgg accgctcgcc
    16621 cgcgggccgg tcgccgtaac ggcgctcgcc ccggccgtcg cggtcgccga accggcgctc
    16681 gccacggtcg gagaagccgc cccggccgcc ccggtcgaag ccccggccgt cccggtcgcc
    16741 gaagcggcgc gggccgccgc gtcgcggctc cggctcgtcc cggacgggta cgccgctggg
    16801 ctcgcgcgcg ccggtcagct cggccagcgc ctcgtcgccc gcccggaccc gggtctcggc
    16861 cggctcgacg cccgccttct ccatcatggc cagggtggtg cggcgctgct tgggcagcac
    16921 gagcgtcgcc accgcgcccg actcgccggc ccgggccgta cggccggccc ggtgcaggta
    16981 gtccttgggg tccttcggcg ggtccacgtg cagcaccagc gacacgccgt cgacgtggat
    17041 gccgcgggcc gccacgtcgg tagcgaccag cacgggcgtg cggccctcgc ggaactcggc
    17101 gagcgtcttg gtacgcattc gctgggtctt gccgccgtgc agcccaccgg cccgcacgcc
    17161 gacggccgcg agctgctcga ccagccggtc cacgccgagc tgcgtacggg cgaacagcat
    17221 ggtgcggccc tcgcgggcgg cgatggacgc ggcgaccgcg aacttgtcgt gcggcgggat
    17281 cagcagcagg tggtggtcca tggtggacac ggcggcggtg gccggcgcgg tcgagtgggt
    17341 gaccgggtcg gtcatgaacc gcttgacgag cgtgtcgacg tcgttgtcca gggtggccga
    17401 gaacagcagc cgctgcgcgt ccgccggggt cttcgacagc agctgggtga cctcgggcag
    17461 gaagcccatg tcggccatct ggtcggcctc gtccagcacg gtgatctcga cgtcgtcgag
    17521 ccggcatacg ccgcgctcga tcaggtcggc gagccggccc ggggtggcca cgacgatctc
    17581 cacgccgcgg cgcagcgcgt cgatctgccg gtcgtacggc accccgccga cggcggtctt
    17641 caggaagacg cccaccgact tgccgagcgg cacgagggcg tcgttcacct gcatggcgag
    17701 ttcacgggtg gggaccagga cgagcgcgcg ggggtgcagc ggccgggccc ggttgcggtc
    17761 ggcgacccgg gcgatcaccg gcaggccgaa ggcgagcgtc ttgcccgagc cggtctggcc
    17821 ccggccgagt acgtcgcggc ccgcgagcga gtcgggcagg gtggcccgct ggatctcgaa
    17881 cggggtggtg atgccctgcc gggcgagcgc ctcgacgagc tgccggggca ggccgagcga
    17941 cgcgaagtcg acggcgtcgg agttcgggtc gacggacggg gacgtgctgg attcagcgaa
    18001 cgtggtcaag aaatgcctct cgagcggggc gcatcttcgc gatggcccgc cgcggcctgt
    18061 cacgccgccg aatcgcccgc aagatcgccc atgagcgcgc aatcggggcg cgccaggtca
    18121 gtaatcggag acaagtgtac ggcgcttcgc ccactccgcc acggcagcgc gaggcggtag
    18181 tgggcgggct cacccccgtc actcgaccgg catggctccg gtcaggccgc tgagcgcgtc
    18241 gttggccagg aagaccacga gcagactgat cgcgatgagc atggtgagcg cgaccgccag
    18301 cacgatgatc accttggtgt tgccgccccg ggccgccggg ctctcctcgg accagccctg
    18361 ggccaggatg tgcccggtca gcgagccgga gttctccagc ggattgccct gcgggaacga
    18421 cacggtggcg aaaccgggtc cgtccgtccc gccgccgtag acggcgccgg cgaggtccgt
    18481 gctgccggac tgctgacgta ccggacgggt cgcgtcggcg tcgcgggccg gcgtggccgg
    18541 cggcggccag gtcggcagcg ccggtgccgg gaccgcgggc ggcggcgggg cggagacggg
    18601 cgcggcggcc cacgccggag gcgactcggc ggaggacgcc ggagtgccgg tcgtggccgg
    18661 cggcgcggac gggaagggcg tggtggccgg cgcgggcggc accgccgagc cggccgacgg
    18721 cgtggcgaac gacggcgggc ccgcggtgac cggtggcgtg acgaacgacg gcgcgcctgg
    18781 ggtggccgac ggcgtgccga acgacgggcc tgcggtggcc ggtggcgcgg ggaacagcgg
    18841 cgcgggcagc gggttcgccg cggccgtcat cgccggtggt ggcgggaacg gaggcgcggg
    18901 catcggaccc ggtgggggcg gcggcggggg caccgcgggt ccgggcggcg gcaccggcgg
    18961 ccccggtacg ggcggaaccg gccccggtgg ggtgggcgcc ggcgcgggcg gcgcgggcgc
    19021 gggcggcgtg ggccggaacg gcggctccgg ctccggcacc ggcggcgcgg gcgacggcgg
    19081 ggtcggaccc ggtaccgggg tcggcgccgg ctcgggctcc ggaccgtgcg gggccggggg
    19141 ctgcgcgggc tccggcggct gggcgggctc gggcggctcc gggttcaccg gacccgcccg
    19201 gtagacggtc gcggcggcgg gagcggtcac caccgaggcg gcgatctcgt cggcggacac
    19261 ccggctcagg ccgggtaccg cggcgctggc ccgggcgtgc gccgtcccgc cttgcccggc
    19321 cggcttcgtg gacagcgccg cattgagccc ggcgggcttc gcggacggcg ccgcatcgag
    19381 gtcggcgggc ttcgcggagg gcaccgcacc cggcccggcc ggttgctcgg cgagggcggg
    19441 ggacgcggtg ccggagtcgg cggacccggc tgccggggcg ccgtcccggg gatcggtggc
    19501 ggtgcttccg gccgcgttct ccggcccgcc cggcgcggcg tcgcggtccg gtcgatcgtc
    19561 ggtcgcgacc gcatccgcgc cggcggcgtc ctcacccggc gtctcgccgc ccgccggagt
    19621 ggacacgcca gccggagcgg ccggtgtgga cgagtcggca ggagcggaaa cggcgggagc
    19681 ggacacggca ggcggaacgg ccggggcagc cgagtcggcg agggccgtcg gagtgggcac
    19741 gggcacccgg gcggaaccgg agacacgggg agccgggata ccggcagccg ggccgtccgg
    19801 cgtggccggg gagggcgtac ccgcagcggg tgtgctgatg ggggcctcgg gtgtcgccgg
    19861 gcgttcggcc acggcgaagg cggaccaggt cgacggggga actgtcgcgc cgggctgacg
    19921 ccggtccagc ggcggggcgt ccgccggggt gcccgcgcgg tacgtggttg ggctcgacgg
    19981 cgccgccggc ggctcgtcgc ctgcgggagg cggtacggcc gccccggcga cggtcacccg
    20041 tgcccgcgcg acggccaccg gcccggggcg ggccgctgcc gggctgtcgt cggcagggtc
    20101 ggcggcgtcg ggcgtcggtc cggggtggac cttctccgcc ggaacctcgt gctcgcccat
    20161 ctcgcccctc cgcacctacg ctcgcccccg accgtggcgc cggccgaaag tgcctggatc
    20221 tcaccgtgcc atattccggc ccgggcgcac agccggagtg cgggttgggt cagtcggcgc
    20281 tgccgctcgc gctggcagag gcgctggcgg acgtgctgcg cgacggggcg acgctgctgc
    20341 tgctcggggc ggcgctggtg ctcggcgcgg cgctcttgct ctcgctcggc gtcggcgtcg
    20401 gctcctcggg cgggctgggc ggcgtgctgg gcgtcgggct ggaggtcgtc gggtccggcg
    20461 tgggcgtggt cggcctcggg gtggtcggcg tcggcctggg ggtcgtcggc gtcggcttcg
    20521 gcgtggtggg cgtcggcttc ggcgtcgggg acgacggcgg cggggtggtc ggcacgggcg
    20581 gcgggggagc cggggtggcc ggggcggcga cggctccgat cacccgggtc gcggcgtaga
    20641 gccgggacca gcggaccacc gagatcttga cgacgtcgcc ggtccggggc gcctccacca
    20701 tcttgccgtt gccgatgtac atggcgacgt ggtggatgct cgtccagctg ctgctggagg
    20761 cgaagaagag caggtcgccg gggagcagcg cgttcggtga gacggtgcgg gagcgggtgg
    20821 cgtagtactg gtccttcgcg acccgcggca ggcccttgta gccggccgac cggtaggagg
    20881 cgagcaccag gccggagcag tcgaaccggt ccgggccctc ggcggcccag aggtacgggt
    20941 cgccgagctg ggcgagggcg tagcgg
//
