LOCUS       NZ_BBVA01000005        45772 bp    DNA     linear   CON 10-SEP-2024
DEFINITION  Micromonospora sp. NBRC 110037, whole genome shotgun sequence.
ACCESSION   NZ_BBVA01000005
VERSION     NZ_BBVA01000005.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Micromonospora sp. NBRC 110037
  ORGANISM  Micromonospora sp. NBRC 110037
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1
  AUTHORS   Igarashi,Y., Komaki,H., Ichikawa,N., Hosoyama,A. and Fujita,N.
  TITLE     Whole genome shotgun sequence of Micromonospora sp. NBRC 110037
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 463339)
  AUTHORS   Hosoyama,A., Ichikawa,N., Kimura,A., Ohshita,R. and Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-MAR-2015) Contact:Director-General Department Of
            Biotechnology National Institute of Technology and Evaluation,
            Biological Resource Center (NBRC); 2-49-10 Nishihara, Shibuya-ku,
            Tokyo 151-0066, Japan URL :http://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Noncontiguous Finished
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: newbler v. 2.6
            Genome Coverage                   :: 106x
            Sequencing Technology :: 454 GS-FLX Titanium; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001652995.1-RS_2024_09_10
            Annotation Date                   :: 09/10/2024 02:06:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,195
            CDSs (total)                      :: 6,136
            Genes (coding)                    :: 6,073
            CDSs (with protein)               :: 6,073
            Genes (RNA)                       :: 59
            rRNAs                             :: 1, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 15 of 63
            Pseudo Genes (incomplete)         :: 53 of 63
            Pseudo Genes (internal stop)      :: 4 of 63
            Pseudo Genes (multiple problems)  :: 9 of 63
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:59:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 145569
            Orig. end                         :: 191341
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBVA01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..45772
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T1PKS"
                     /region_number="3"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..45772
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..45772
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:25772](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..25772)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     gene            complement(979..1704)
                     /locus_tag="A4R25_RS16985"
     CDS             complement(979..1704)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018790147.1"
                     /locus_tag="A4R25_RS16985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF899 family protein"
                     /protein_id="WP_064447363.1"
                     /transl_table=11
                     /translation="MTEDASAPALPMWPDGADAGYVAARLRLAEVERRLCDQIEQVAAA
                     RRELPLGAPVADVALTEGPADLTAPGPLRPVRLSALFGAHRTLLVYHLMFHPDADAACP
                     MCSMWVDGFHGVAHHLRQHTAFVVVGKAPAEKLRAWGARRGWAGLRLLSSHGTDFNADL
                     RAEHPNGDQRPMVSVLVRDGDGVRHFYSQPANFVDGTERGIDLLSPVWNVLDLLPRGRG
                     DWYAANTYPPVADPADRPV"
     gene            1799..3202
                     /locus_tag="A4R25_RS16990"
     CDS             1799..3202
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788304.1"
                     /locus_tag="A4R25_RS16990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NDP-hexose 2,3-dehydratase family protein"
                     /protein_id="WP_064447364.1"
                     /transl_table=11
                     /translation="MTETTAPPGLPQHGRFATADPDADIHEWLADWRRQAPMRVDVVPL
                     AGLRGWRQDADTGVLAHRSGRFFRVEGLSVEVPGAAVPRWDQPVLHQPEVGILGLLARR
                     DGDTLRVLVQAKAEPGNQDGHQLAPTVQATRSNWTGVHGGRPVPFLHHFRDPDPRRVLV
                     DVRQSEHGSWFLRKRNRNMVVLTDEDIVPPPGFRWLSLAQLHRLLRHDDLVNMDIRTVL
                     SCLPAELTARAAGPAGDAFTAALRRSCRPGPGSRHHTGELLHWITDVRSRTEVDADRTA
                     LRGQAAWHLGEVSLRHDSGLFFEVIGVDVDAEGREVASWSQPMLRPCGQGVVAFLATRL
                     DGVLHVLAHARVEPGFVDVVELAPTVQCTPATLDYLPAAARPPFLDQVLGAPPERVRFR
                     ALLSEEGGRLYRARSSYLVVETDDVDLESDQYRWVTLHQLSELLRHSNYVNVSARSLIA
                     CLRGLLDAG"
     gene            complement(3247..3678)
                     /locus_tag="A4R25_RS16995"
     CDS             complement(3247..3678)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018744935.1"
                     /locus_tag="A4R25_RS16995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SRPBCC family protein"
                     /protein_id="WP_176722772.1"
                     /transl_table=11
                     /translation="MLIRRPAAEVFEAFADPAVTTKFWFTKSSGRLEPGATVTWDWEMY
                     GVSTVVTVKDVEKNSRILAEWDPESPTQLEWRFLPGEGDTTLVRVTETGFAGSADQAVA
                     KAIDSMGGFTMVLCACKALLEQGVLLNAVGDAHPTGFGD"
     gene            complement(3780..4595)
                     /locus_tag="A4R25_RS17000"
     CDS             complement(3780..4595)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018815184.1"
                     /locus_tag="A4R25_RS17000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_205798118.1"
                     /transl_table=11
                     /translation="MVETGTGRGASAPSAARPARPGALSSTLTFAWRAVQKVRRDPTQI
                     LEALGVPVMFTLVFGFLFGGALAGSTSSYMQFYIPGIVVFTGIMISMRIGAVVNLDNSR
                     EVTDRFRALAIWRPAAIVGTLLGNNVLYVVGCAVAVAVGLAVGFRPDGGVLGVLATILI
                     TLVFVFSFSWVYVVFGLALKSPTAALSACQAIVFPVSFVSNFFVPQETLPGWLQAVVGL
                     NPFALTVTAARGLAHGTATAGEVGAALVGCAALVAVFAPLSMFLYRRRA"
     gene            complement(4601..5605)
                     /locus_tag="A4R25_RS17005"
     CDS             complement(4601..5605)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018744933.1"
                     /locus_tag="A4R25_RS17005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_064447365.1"
                     /transl_table=11
                     /translation="MSRTAGLSAQQTDTPAIEITRLRKSYGEVRALDGIDLRVSAGSVF
                     GVLGPNGAGKTTIVRTLATLVPPDSGEVRVLGHDVVREAGAIRDRIGLTGQYSSVDEEL
                     SGRDNLVLLSRLRGFSWSAARRRAEELLATFGLKEAAARLVRTYSGGMRRRLDIASSMI
                     VTPDLMFLDEPTTGLDPHSRNQVWELVRGMVGEGATVLLTTQYLDEADQLADRIAVVDH
                     GRVIAEGTPVELKRSIGASVLRVRLRDAGQRETAERMLAEALGTAVHAGADRMELTAQV
                     AAEEEATRALAALTGAGVGLAEYAFGHATLDQVFLALTGHRADGSRTETEEAA"
     misc_feature    complement(5605..5618)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.38"
                     /tool="antismash"
     misc_feature    5630..5644
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.31"
                     /tool="antismash"
     misc_feature    5729..5743
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 15.9"
                     /tool="antismash"
     gene            5770..6594
                     /locus_tag="A4R25_RS17010"
     CDS             5770..6594
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (29-169). E-value: 1.9e-38. Score:
                     123.7. Matches aSDomain:
                     nrpspksdomains_A4R25_RS17010_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788300.1"
                     /locus_tag="A4R25_RS17010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cyclopropane-fatty-acyl-phospholipid synthase
                     family protein"
                     /protein_id="WP_064447366.1"
                     /sec_met_domain="PCMT (E-value: 2.1e-07, bitscore: 25.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRELTEVDEVAEIYDDGAWAVEVLGGNIHFGWWEDDDDRTPFL
                     EAINRFTDIVGDRLGLRPGDRLLDVGCGAGEPAIRLGQRSDADITGITNSAEHLKRARE
                     RVNESGLRGQVRFELGDAAALSYPDASFDKVLAFESLVHAQDRRQWLAEIRRVLKPGGR
                     LVLTDLAEDAPLTERDRQILTDFTLAPPGPPMAAFDLVRDAGFVVDEFLSCGDKISRSF
                     PAYHERVQQRRDTLAAAHGAEKIDAFLAEMPAVLDVLRTKVGCVVIAAHKPR"
     aSDomain        5857..6276
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R25_RS17010_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.90E-38"
                     /label="A4R25_RS17010_oMT.1"
                     /locus_tag="A4R25_RS17010"
                     /protein_end="169"
                     /protein_start="29"
                     /score="123.7"
                     /tool="antismash"
                     /translation="IHFGWWEDDDDRTPFLEAINRFTDIVGDRLGLRPGDRLLDVGCGA
                     GEPAIRLGQRSDADITGITNSAEHLKRARERVNESGLRGQVRFELGDAAALSYPDASFD
                     KVLAFESLVHAQDRRQWLAEIRRVLKPGGRLVLTDL"
     gene            6630..7862
                     /locus_tag="A4R25_RS17015"
     CDS             6630..7862
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788299.1"
                     /locus_tag="A4R25_RS17015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_064447367.1"
                     /transl_table=11
                     /translation="MTAPAVTGCRICGGPVTEMLDLGRQPLSDAFPLPADLDGEFFYRL
                     AVGRCADCTMVQLVEEVPRERMFHHDYPYRSSLSSVMRAHFTGTGRELLATELTRPGAF
                     CVELGCNDGVMLRTVAAAGVRHLGFEPSAGVAELARGQGVRVRTDFFEEETAADVLATD
                     GPADVIYAANTICHLPYLDSVLRGARLLLAPGGVLVFEDPYLGDILARTAFDQIYDEHF
                     YYFTAHSVRAAAARFGLELVDVRRLPVHGGEVRYTLARAGARTPSPAVADLLRQEREQG
                     VTGEAALRRFAAAVARTRSELVALLRSLREEGRTVAAYGATAKSATVTNYCGLGPELIS
                     YVCDTTPAKQGRLTPGAHIPVRPPEAFADPYPDYAVLFAWNHAEEIMAKETGFRAAGGR
                     WIHYVPTVRVR"
     gene            7859..8611
                     /locus_tag="A4R25_RS17020"
     CDS             7859..8611
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788298.1"
                     /locus_tag="A4R25_RS17020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="trans-aconitate 2-methyltransferase"
                     /protein_id="WP_231915557.1"
                     /transl_table=11
                     /translation="MTASVARGFYRAGYPEIYDLVMRHRGRDHIAEAATLARTVRRRNP
                     AAASLLDVACGTGLHLEHLRTHFAPVTGVDLSGEMLARAGARVPDVALHEGDMRDLDLA
                     DTFDVVVCLFAVPHLRGAAELDRTVARLAAHLTPGGVLAVEPWYTPETFVPGYVARDMV
                     QEQDRVVVRLSHSTWLDDARDRIRMTVHQAYADPEAGIRHDTATTDLTLFRPQHFAAAF
                     ARAGLAAAHVTAPPFRWGLWIARPAGAR"
     gene            8608..9591
                     /locus_tag="A4R25_RS17025"
     CDS             8608..9591
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788297.1"
                     /locus_tag="A4R25_RS17025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_064447368.1"
                     /transl_table=11
                     /translation="MTGDRPRAVVLGGTGFVGAHVADAFADAGHDVLTVARRAPAGDRH
                     RFTALDLGGTGPGTLARLLDAEDPVAVVDSTGSSWGLDPGRMAERCTRLSALLLDALRR
                     AACRPRLVHLGSVLEYGQPVAPADPRRTPAPDTAYGRAKLAATRAVLAAADAGEVDAVV
                     LRLVNALGPGLPATSLLGRVAAALAPAARAGVAARVTLAPLEARRDFVDVRDAAEAVLA
                     AAGRPVTGRVLDIGRGEAVPVRTLVRLLVQVSGVQATVVERAGPAGWRAGTRWSCVDPA
                     PAAAALGWRPRRDLRRAVTDFWHDELRRYSGDGEPAAAGPPRQRAP"
     gene            9687..10802
                     /locus_tag="A4R25_RS17030"
     CDS             9687..10802
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018744928.1"
                     /locus_tag="A4R25_RS17030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleotide disphospho-sugar-binding
                     domain-containing protein"
                     /protein_id="WP_064447369.1"
                     /sec_met_domain="MGT (E-value: 4.3e-100, bitscore: 330.3,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLFMPGPAIGHAFPLVPLGWAFRAAGHEVVFVTAGDALAVARA
                     GLPVLDAVPGRTTSDMQAQFIRDVPRLFEPIGADPIAEMEERKPYIVSAWDPFVDAHVA
                     LGEWVQPDLVVYDPIFAVGPVVAARLKVPAVAHSLGLARFTPDLLRELPGAVAMRRHGV
                     TLPEGIRTVDIAPPSLVEGGPADISMRYVPYNGGGVLPEWLREPVARPRIAVTFGTLGG
                     PDRFAAGIARVLAAAPGLDAEFVLAIGESAAPPDLPPNVRTTGWVPLNQLLRGCAAAIH
                     HGGDGTTLTCAALGVRQLVLPGSPDELVTGELLRARGLAHVLGSVDELDAAAIGRLLTD
                     AELGRVTGEVRAEIAALPSPAEVVPRLTAAV"
     gene            complement(10846..12600)
                     /locus_tag="A4R25_RS17035"
     CDS             complement(10846..12600)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4R25_RS17035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_197494921.1"
                     /transl_table=11
                     /translation="MPRPQLRGPLRRAAHIGVIALVAVSSGLVPPPAAAGASVRRVTST
                     VTGSDGQPYRITNHLTRTAQAAERPGAPARQWLLVWTGDAAPGPDGRPDPDFLAVVDAT
                     PGSPDYGRVANTVTVDSVFGNEPHHMQYTWRKGDKVYAGGLLSDTVYVFDVSRLPRVSL
                     SGVTLPHDTPCGSVPDAFTVLRDGTAYGSYMGGPDVAGPCTYSDGQTRVGNGFAGSPGE
                     VVRLGADGRVLAEMPAAKKTAEDPVSCPNQPALPVPTCANPHGIALREDLNRLVTSDFV
                     EVRHVVAGLVTDPNLQRRTVRTYDISDRNRPRLLSLSYLPDGPRVDDEYSREGLLAMEP
                     AVTHQPRHKGAFVATGMGAVYYTPDITKRELTWRQVFDDATAFRRIYPRDTPTSAADGG
                     SWLMVSPDDRFLFHTVMFGGNNSPAVNAESGMVYVLDIRRLLAAGSRTSCRIDTIAETV
                     RGGAEPDCPALVSALPIVDTTLGGPHWGAMDTFRPVAGGKHFRQTDQVSRVVTSNYFVA
                     PTGLDGDARICMALVDPAGRLTEDRAFRDEHTGRRCVSFDRTSWPHGDTGKANPHGLLF
                     AVADAQLR"
     misc_feature    12709..12721
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.54"
                     /tool="antismash"
     gene            13071..14180
                     /locus_tag="A4R25_RS17040"
     CDS             13071..14180
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788294.1"
                     /locus_tag="A4R25_RS17040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="WP_064447370.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.8e-120,
                     bitscore: 396.5, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIGVWNYLAEYESEREDVLGAVDQVFSSGRLVLGESVRGFEREF
                     AAYHGVPHCVGVANGTDAISLALWALGVRPGDEVVTVANTAAPTVLAIDAVGAVPVFVD
                     VDEATCLMRVDRVADVITPRTRVLLPVHLYGQCVEMAPLRALAAAHGLAVLEDCAQAHG
                     ARHHGRVAGSLGDAAAFSFYPTKVLGAYGDGGATITADPDVERRLRRLRYYGMEDRYYV
                     EETPGRNSRLDEVQAEILRRKLRRLDRYVAARRAIARRYDEGLAGTGLGLPVTAPGNEH
                     VYYLYVVRHPRRDEILAALRRHGIELNVSYRWPVHTMRGFAHLGYTEGSLPVTERLAGE
                     IFSLPMYPSLDEGAQARVIDALRTILRAW"
     misc_feature    14205..14220
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.19"
                     /tool="antismash"
     gene            14254..14799
                     /locus_tag="A4R25_RS17045"
     CDS             14254..14799
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018744927.1"
                     /locus_tag="A4R25_RS17045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_064447371.1"
                     /transl_table=11
                     /translation="MEPSTFSTPVGDFADLRDDFLRLTTEIGWCTVATVDGRDRPRSRI
                     MHVSWEVGDAGPTGWVSTSRTPVKTAHLARNPYVSCSYWTPAHDAVFVDCHATWLEPGD
                     TKRHVWDLVAAEATQRGFDPYAVWPDGPADAGFEVLQFDPWRVQITLQDLANGQTIGSS
                     RVWHAAGRPASTGALLSR"
     gene            14886..16229
                     /locus_tag="A4R25_RS17050"
     CDS             14886..16229
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788292.1"
                     /locus_tag="A4R25_RS17050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_043325274.1"
                     /sec_met_domain="p450 (E-value: 5.7e-82, bitscore: 270.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTLRTPASAPGRLPVLGHGLQMKRRPAEFLLELQSGEPVVTIA
                     LGKRPAYVVNDPTLMRELLRDGDTFVRGGPMTERFRSMFGNGLGISEGEFHRRQRALIQ
                     PAFHRNKVIHYTELMSRTVAGKLDSWRDGQRLAVEKEMDELALTNVVEVVFAGDRSLDR
                     ARFMAATTTVLGGLFRRITDVTGVLTRLPTQANRDYDTAAEYLRATIRRVIAEYRAAGT
                     DHGDLLSMMLFARDEDGRPAMSDEQVHDEVMTFFIAGSNTIANTLCWALHHVGADPEVQ
                     RRLHAEVDRVLDGRAAGYADVPALEYTRQVLSETLRLRTQGLFNNRVTARDAELGGYLI
                     PAGSDVLYSFHAVHHNPRIYPEPELFDPDRWLPERARTLPRGAFMPFATGVHGCIGDQF
                     AWTEMIVSLASIAARWRLEPVPGHEPKPVPAMTMPVDALPMTARRRTR"
     gene            complement(16285..16827)
                     /locus_tag="A4R25_RS17055"
     CDS             complement(16285..16827)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018815178.1"
                     /locus_tag="A4R25_RS17055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_030503321.1"
                     /transl_table=11
                     /translation="MTTELQRRKLEKVFASYDADGDGVIDGLDITAMAQIWCDTYGVAP
                     YSPGWRRIHGAAARMWRGMRGSDGPDGEKRVTVAEWVAWADKPEFPEFVTNAAVPFSLA
                     VFDVADADRDGRINHAEMFAAQSKSGMRSEDTQRIFDRLDTDRDGYLTSEEYGRAAHEF
                     YLSADPDAPGNVIAGEL"
     gene            complement(16855..17715)
                     /locus_tag="A4R25_RS17060"
     CDS             complement(16855..17715)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018815177.1"
                     /locus_tag="A4R25_RS17060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_064447372.1"
                     /sec_met_domain="PCMT (E-value: 1.1e-06, bitscore: 23.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVSTDAAAVKAEQRRTWDAVSDGWTREWETFERGGAALTARLLA
                     LGGVRPGHRVLDVATGPGEPALSAADIVGPAGTVTGVDLSPAMLAVARRRAEGRRNVNF
                     LVADLETVELPPHAFDVVLSRLGLMFAVDPGAAFGRIARLLVPGGVLAAAVWAPPPRVP
                     LMSLGYGVLARRLDLPSGPPDAPGPYRLCDPEALAAGLTDAGLRDVTVEEYPVPFRFHD
                     PAEYARFTRAVAPPPVRRRVEALDPAGRDALWAEVAAAAEGRAGPDGLVDLTSTALTVR
                     AVAPH"
     misc_feature    complement(17711..17722)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.61"
                     /tool="antismash"
     gene            complement(17742..18437)
                     /locus_tag="A4R25_RS17065"
     CDS             complement(17742..18437)
                     /GO_component="GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046688 - response to copper ion [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016149.5"
                     /locus_tag="A4R25_RS17065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="copper resistance CopC family protein"
                     /protein_id="WP_064447373.1"
                     /transl_table=11
                     /translation="MRRGPGLRWLAAGLLTLLALGLAGLTLAAQLRPARLVTTDPPAGA
                     RLTTAPAAVTLTFNGPLDAERTHVWLIGPGGAFGATGAPRYRDNGVEVPVTVVGDGRYR
                     VGYHAQLATGQTATGVVPFTVAAGLGAPPRAAPAASPPATAPPDGSAGGGHHGGTGGAA
                     GLALLLAPVVTGAVLLVLMARGRRDRPAGGTPSSAGPGPGGRRRAWVLREPEDAGDRPA
                     DREPARPGG"
     gene            complement(18434..18997)
                     /locus_tag="A4R25_RS17070"
     CDS             complement(18434..18997)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788288.1"
                     /locus_tag="A4R25_RS17070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_051611104.1"
                     /transl_table=11
                     /translation="MTLSDKRDAGASGLDLNGSRHRAALQIFLVVVIAHWAEHLVQAAQ
                     IWVFGWSRPEARGVLGMPFPWLVESEWLHYGYALVMLAGFWLLRGGFVGRARTWWMAAL
                     LIQVWHHLEHLLLLVQSLTGSNLAGQPVPTSLLQLVAPRVELHLFYNAVVFLPMVVAMY
                     LHRTPLADELARMRCSCRRVAEVR"
     gene            complement(18994..19557)
                     /locus_tag="A4R25_RS17075"
     CDS             complement(18994..19557)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788287.1"
                     /locus_tag="A4R25_RS17075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavin reductase family protein"
                     /protein_id="WP_231915558.1"
                     /transl_table=11
                     /translation="MPERAVDAPPATAALRTVLGEFVTGVTVLTVGGPLPHGMTANSFT
                     SVSLDPPLVLLCVSRDSLMSACLSDADGFGISVLAGGQERLARHFADRRRRPGRAQFAA
                     VGWSPGERTGAPLLHGALAWLECRPWRCHDGGDHVIVVGRLVAARTAADSDALIFRRGR
                     FDRYGNSHPAAGRRHVQPLLKEAQ"
     gene            complement(19550..19999)
                     /locus_tag="A4R25_RS17080"
     CDS             complement(19550..19999)
                     /EC_number="3.1.2.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788286.1"
                     /locus_tag="A4R25_RS17080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thioesterase family protein"
                     /protein_id="WP_030503316.1"
                     /sec_met_domain="4HBT_2 (E-value: 2.9e-11, bitscore: 38.6,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAWYEYRHVVGFEETNLVGNVYYVNYLRWQGRCREMFLREHAPA
                     VVDDLRAGLKLFTLRVDCEYLAELDAFDELRIRMSLTELTQTQLGLAFDYLRDGPGGLV
                     PVARGHQRIACMREVAGQVVPTRVPTPLVRALAPYRAAEGVAGRA"
     gene            complement(20001..25772)
                     /locus_tag="A4R25_RS17085"
     CDS             complement(20001..25772)
                     /NRPS_PKS="Domain: PKS_KS(Enediyne-KS) (3-460). E-value:
                     1.2e-95. Score: 312.8. Matches aSDomain:
                     nrpspksdomains_A4R25_RS17085_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (611-841). E-value: 2.6e-58.
                     Score: 189.7. Matches aSDomain:
                     nrpspksdomains_A4R25_RS17085_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1199-1380). E-value: 1.6e-39.
                     Score: 127.6. Matches aSDomain:
                     nrpspksdomains_A4R25_RS17085_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_DH (1454-1582). E-value: 1.9e-13.
                     Score: 43.1. Matches aSDomain:
                     nrpspksdomains_A4R25_RS17085_PKS_DH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     ene_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018803583.1"
                     /locus_tag="A4R25_RS17085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_064447375.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 1e-56, bitscore:
                     187.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="ene_KS (E-value: 6e-255, bitscore: 840.6,
                     seeds: 19, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.8e-57, bitscore: 189.7,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 4.4e-35, bitscore:
                     116.0, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRIAVVGMSCRYPEADSVADLWRNALSGRRAFRRLPPERMSLED
                     YWDADPATPDRFYNRHAAVIEGYTFDRIRHRIAGSTYRSTDLTHWLALDVAGEALADAG
                     WPDGAGLPRDRTAVVVGNTLTGEFSRANVLRLRWPYVRRVLAAGLQEQGWPDRRIAEFL
                     AVTEERYKSPFPPIDEDTLAGGLSNTIAGRICNHFDLGGGGWTVDAACASSLLSVVTAA
                     RALADGEVDVAVAGGVDLSIDPFEMVGFAKAGALARDEMRVYDERSQGFWPGEGCGMVV
                     LMRHDDAVAQGRVVHATIAGWGVSSDGRGGMTRPEAHGYRLALDRAYQRAGFGIGTVPL
                     FEGHGTGTAVGDATELRALSAARRDAGATDPAAIGSIKALIGHTKAAAGVAGLIKATMA
                     LRHAIVPPTAGCARPRAELTAADRTLRAAPVAEPWPDGAPLRAGVTAMGFGGINTHLVL
                     EAGPSAVPERVRRQQLRLARHTQDAELLLLDAADPVALRERVAALLDPLARLSYGELTD
                     LAGALAGEVRGRPMRLAVVAASPAEAVDRFERVLAALDRGEEELFADGLALRRTLRPAR
                     LGFLFPGQGSGRGVDGGALARRFPAAGEVHRLAALPADADPVATEVAQPRIAAGSLAGL
                     RVLTELGVEARVAVGHSLGEITALHWAGTVDAEALLRIAAARGAVMAGCREPGTMAGIA
                     ADDTVTARLIGAEPVVVAGYNGPRQTVVAGPSDAVRRVCERATDAGVHWADLAVSHAFH
                     SPLMASAAREFGDWLEGVRLTPPRRPVVSTVTGAELTSGTDLAALLRRQITEPVRFAAA
                     VTEAGRRVDALVEVGPGQVLARMARELVDVPVFATGTDAPTLAGFLGTVGALWTLGAPV
                     DHAALVSDRPIRPLDLAARRRFFANPCEAAPAVAVAAASPTGATPQAAGGPVTVDETAP
                     AGGGPAADPLAVLRRLAASRAELPPESVGADTRLLDGLHLSSIAVGQLVNEAARELGLP
                     AVQAPTNFATATLREIADALRELDPAAPPADRRVDGVAPWVRGFTVELVEEPVEPAGAG
                     PGGPGAWQWYAPAGHPYAEALRDALAGAGVGGGVLLCPGEEVDLDLALRAVQAAVAQPP
                     GARLVVVQHGRGVAGLARTARLEGSGLHVTLVEAAPADDLVGRVVREVAATDGYAESHL
                     GPDGRRRVPLLRPLPPPGPARPGPAGPPLRPDDVLLVTGGGKGITAECALALARDTGAR
                     LALLGRADPAADPELAANLTRMREAGVRLRYVRADVTDPEAVRAAVAQVRAHLGPVAGV
                     LHGAGVNRPAALGALDPDTLRATLAPKVDGLAHVLTAVEPDELRLLVTFGSVIGRGGLP
                     GEAHYALANDWLARLTAEAGRRFTGCRAVCLEWSVWSGVGMGERLSAVESLLRAGITPI
                     PPDEGVRLLRQVLALPRLPASVVVTGRTDGLDTLRHERRELPLLRFLERPLVQYDGVEL
                     VVEADLSAESDPYLAEHDLDGNLLLPAVLGMEAMAQVATALAGATGVPVLTGVSFPRPV
                     VVARGGRVTVRIAAVQAEAGVVEVAIRSDETGFAADHFRGTVRFEPDEGDREAPGVTGG
                     LPPVPLEPGRDLYGDLLFQGDRFRRLVRYHRVASRRAEADVATTEDMRWFHAFLPQRLL
                     LGDAGARDAFLHGIQVCVPDATLLPIAVDRVEPAGPKLAATEQVRFVAVEREHRDDTYR
                     YDVTVLGAAGTVVERWLGLRLRAVRHRPAALPWPPALLGPALERRLGRLLDADLAVVVE
                     PRPDRTGGARREVTAVAVGRAVGRPVRLRYRPDGRPEEVNGRHVSAAHSEVASLLVAGA
                     GPLACDLEVVRPRPAEVWADLLGRHAGLAGQIAADLGEDADVATTRVWCAKECLVKAGL
                     PVDAPLTVAGGDGEWVLVRSGRVTVATGPVRLTGEPQPVVVAVLTATGV"
     aSDomain        complement(21027..21410)
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R25_RS17085_PKS_DH.1"
                     /evalue="1.90E-13"
                     /label="A4R25_RS17085_PKS_DH.1"
                     /locus_tag="A4R25_RS17085"
                     /protein_end="1582"
                     /protein_start="1454"
                     /score="43.1"
                     /tool="antismash"
                     /translation="QYDGVELVVEADLSAESDPYLAEHDLDGNLLLPAVLGMEAMAQVA
                     TALAGATGVPVLTGVSFPRPVVVARGGRVTVRIAAVQAEAGVVEVAIRSDETGFAADHF
                     RGTVRFEPDEGDREAPGVTGGLPP"
     aSModule        complement(21027..25763)
                     /domains="nrpspksdomains_A4R25_RS17085_PKS_KS.1"
                     /domains="nrpspksdomains_A4R25_RS17085_PKS_AT.1"
                     /domains="nrpspksdomains_A4R25_RS17085_PKS_KR.1"
                     /domains="nrpspksdomains_A4R25_RS17085_PKS_DH.1"
                     /incomplete
                     /locus_tags="A4R25_RS17085"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(21489..21512)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R25_RS17085_0005"
                     /evalue="9.90E+01"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="A4R25_RS17085"
                     /protein_end="1428"
                     /protein_start="1420"
                     /score="-3.4"
                     /tool="antismash"
                     /translation="PASVVVTG"
     aSDomain        complement(21633..22175)
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R25_RS17085_PKS_KR.1"
                     /evalue="1.60E-39"
                     /label="A4R25_RS17085_PKS_KR.1"
                     /locus_tag="A4R25_RS17085"
                     /protein_end="1380"
                     /protein_start="1199"
                     /score="127.6"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="VLLVTGGGKGITAECALALARDTGARLALLGRADPAADPELAANL
                     TRMREAGVRLRYVRADVTDPEAVRAAVAQVRAHLGPVAGVLHGAGVNRPAALGALDPDT
                     LRATLAPKVDGLAHVLTAVEPDELRLLVTFGSVIGRGGLPGEAHYALANDWLARLTAEA
                     GRRFTGCRAVCLEWSVWS"
     CDS_motif       complement(21696..21794)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R25_RS17085_0004"
                     /evalue="9.40E-06"
                     /label="PKSI-KR_m4"
                     /locus_tag="A4R25_RS17085"
                     /protein_end="1359"
                     /protein_start="1326"
                     /score="18.2"
                     /tool="antismash"
                     /translation="LRLLVTFGSVIGRGGLPGEAHYALANDWLARLT"
     CDS_motif       complement(22080..22169)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R25_RS17085_0003"
                     /evalue="5.70E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="A4R25_RS17085"
                     /protein_end="1231"
                     /protein_start="1201"
                     /score="12.6"
                     /tool="antismash"
                     /translation="LVTGGGKGITAECALALARDTGARLALLGR"
     aSDomain        complement(23250..23939)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R25_RS17085_PKS_AT.1"
                     /evalue="2.60E-58"
                     /label="A4R25_RS17085_PKS_AT.1"
                     /locus_tag="A4R25_RS17085"
                     /protein_end="841"
                     /protein_start="611"
                     /score="189.7"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="PADADPVATEVAQPRIAAGSLAGLRVLTELGVEARVAVGHSLGEI
                     TALHWAGTVDAEALLRIAAARGAVMAGCREPGTMAGIAADDTVTARLIGAEPVVVAGYN
                     GPRQTVVAGPSDAVRRVCERATDAGVHWADLAVSHAFHSPLMASAAREFGDWLEGVRLT
                     PPRRPVVSTVTGAELTSGTDLAALLRRQITEPVRFAAAVTEAGRRVDALVEVGPGQVLA
                     RMARELVD"
     CDS_motif       complement(23601..23639)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R25_RS17085_0002"
                     /evalue="5.40E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="A4R25_RS17085"
                     /protein_end="724"
                     /protein_start="711"
                     /score="10.2"
                     /tool="antismash"
                     /translation="AGYNGPRQTVVAG"
     CDS_motif       complement(23727..23846)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4R25_RS17085_0001"
                     /evalue="1.30E-07"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="A4R25_RS17085"
                     /protein_end="682"
                     /protein_start="642"
                     /score="23.6"
                     /tool="antismash"
                     /translation="VEARVAVGHSLGEITALHWAGTVDAEALLRIAAARGAVMA"
     aSDomain        complement(24393..25763)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R25_RS17085_PKS_KS.1"
                     /domain_subtypes="Enediyne-KS"
                     /evalue="1.20E-95"
                     /label="A4R25_RS17085_PKS_KS.1"
                     /locus_tag="A4R25_RS17085"
                     /protein_end="460"
                     /protein_start="3"
                     /score="312.8"
                     /tool="antismash"
                     /translation="IAVVGMSCRYPEADSVADLWRNALSGRRAFRRLPPERMSLEDYWD
                     ADPATPDRFYNRHAAVIEGYTFDRIRHRIAGSTYRSTDLTHWLALDVAGEALADAGWPD
                     GAGLPRDRTAVVVGNTLTGEFSRANVLRLRWPYVRRVLAAGLQEQGWPDRRIAEFLAVT
                     EERYKSPFPPIDEDTLAGGLSNTIAGRICNHFDLGGGGWTVDAACASSLLSVVTAARAL
                     ADGEVDVAVAGGVDLSIDPFEMVGFAKAGALARDEMRVYDERSQGFWPGEGCGMVVLMR
                     HDDAVAQGRVVHATIAGWGVSSDGRGGMTRPEAHGYRLALDRAYQRAGFGIGTVPLFEG
                     HGTGTAVGDATELRALSAARRDAGATDPAAIGSIKALIGHTKAAAGVAGLIKATMALRH
                     AIVPPTAGCARPRAELTAADRTLRAAPVAEPWPDGAPLRAGVTAMGFGGINTHLVLEA"
     gene            complement(25805..26776)
                     /locus_tag="A4R25_RS17090"
     CDS             complement(25805..26776)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018829929.1"
                     /locus_tag="A4R25_RS17090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_043325264.1"
                     /transl_table=11
                     /translation="MTKPRDPRVTALRRFAISITVLNILGYTVLGFEQPALWPVYAVLT
                     AYAAELLLEAVGARGEGRAPRYAGGVRNLVEFLFPAHITALAVNMLLYTNDRVLVMLFG
                     VLVAISGKWLLRAPVNGRLRHFMNPSNFGIAIVLLLFPWVSIAPPYHFTENLSGPADWA
                     IVAVILVLGTMLNAKLTRRMWLIAGWLSIFVVQSVVRGLVLDTSIVAALATMTGTAFVL
                     FTNYMITDPGTTPSRPAAQFAFGGGVALVYGVLTGASVTYGLFFATAIVCLVRGTFLWS
                     LHASRREQRRREQDQPVSPATPGTPATAGPVSADNGKRPVPA"
     gene            complement(26773..28725)
                     /locus_tag="A4R25_RS17095"
     CDS             complement(26773..28725)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019032452.1"
                     /locus_tag="A4R25_RS17095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CRTAC1 family protein"
                     /protein_id="WP_064447376.1"
                     /transl_table=11
                     /translation="MSMILGWGRRHLAGLTALLLIVGLFLIAEPATATDEERRRVAAGY
                     RFTPLSIAIPGGLPQQSIRRVNKEYTHIDAWISSVGAGVAMNDIDGDGLANDLCVTDPR
                     IDRVVVTPTPGARQERYQPFVLDPAPLPMGPHMAPMGCAPGDFNEDGRTDLLVYWWGRT
                     PVIFLARPDATGLSAAAFQPVELVPRPAAADGGYTGPRWNTNTVSVADFDGDGHEDVFV
                     GNYFPDGPVLDHTVSGGVAMNRSMSAAYNGGRDHVLRWTGATADSVTFADVPDLFDDDV
                     SRGWALASTATDLDGDLLPELYVANDFGPDRLLHNRSTPGRVRLALVEGEGSRLTVPKS
                     KILGHDSFKGMGVDVGDLDGDGLYDMYVGNITTSFGIQESNFAFVNQARDTDDLRQRLA
                     DGRAPFVDRSAPLNLAWSGWSWDVKIADLTNSGRPDIVQTSGFVKGEVNRWAQLQELAT
                     ANDTLLEHTSAWPRVRQGDDIAGGQPLRLHARMPGGAYADIAGQLGLAVPIPTRGIALG
                     DADGDGRLDMAVARQWDAPVFYRNDSPGTGSQLSLKLNRPPAGDAATGSPVIGADVTVR
                     TPDGRVLRGRVDGGSGHSGRRSFEVHIGLGDVTGPVQVDLAWRDRTGAPRAQTVTLAPG
                     RHALTLGTQAQEASS"
     gene            complement(28730..29701)
                     /locus_tag="A4R25_RS17100"
     CDS             complement(28730..29701)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019872121.1"
                     /locus_tag="A4R25_RS17100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1702 family protein"
                     /protein_id="WP_064447377.1"
                     /transl_table=11
                     /translation="MARILLALRQRILTPDKREALFDTRGFHVKNDAARQALESAGQSF
                     IGGFGDAAGAPEPRAAEELLESRPAPLRGFAYEGAAMAYALMDGLRPGGGRGMARFLAG
                     RGDAHVYMAHVGAGWAMARLPRWRRPAILPPDPLLRWLALDGYGFHQAYFHTGRYVHAR
                     HRDPAHIWPAELRHYAPHAVDQGIGRALWFVAGADPAELVRLLHRFPADRHSDLWSGVG
                     LAASYAGGADLTELRTLREAAGEHRAALGQGAAFAAKARMRAGHVPTHTAVAVGAFCVT
                     SIEQAAAITDAALTDLTDSASLPAFAVWRQRIADHLVLLGRC"
     gene            30115..30921
                     /locus_tag="A4R25_RS17105"
     CDS             30115..30921
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018744920.1"
                     /locus_tag="A4R25_RS17105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_223201160.1"
                     /transl_table=11
                     /translation="MKRELGRPLPLETLARLAPFSPFYFHRVFKQATSMTPARFLAALR
                     MAEARRLLLRSSLTVTAISAQVGYSSVGTFTTQFRRWVSLPPERFRQLARQLAGVSVAA
                     LLPVIRSRAIVAGQGPRALMHLDTVDLPGLLLAAVAPHDGGRNEWWTAAPRPLPAALPA
                     TVPPGEHRARVLLLRPDRDATSALVDGAPDSFLIGDADLRIPAETGSAQRITVARATLT
                     VPVRQVRVTDPPLLSATPLRWLLGVSQAGWRGRTPVMAERRALRTA"
     gene            30921..31898
                     /gene="add"
                     /locus_tag="A4R25_RS17110"
     CDS             30921..31898
                     /EC_number="3.5.4.4"
                     /GO_function="GO:0004000 - adenosine deaminase activity
                     [Evidence IEA]"
                     /GO_function="GO:0019239 - deaminase activity [Evidence
                     IEA]"
                     /GO_process="GO:0043101 - purine-containing compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /gene="add"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018815176.1"
                     /locus_tag="A4R25_RS17110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenosine deaminase"
                     /protein_id="WP_197494922.1"
                     /transl_table=11
                     /translation="MAVPAPKIELHVHFEGTVRPETLLVIARRNGQRLPAETVEGLRQL
                     YEFTDFDHFVRTWVLTTNCLRTADDFRRIVVAYAAEAATHGAVYLEGIFSPAERVRRGV
                     GWADIFEGYADGAAEAYERHGVRVLLTPDVDRELAPADAEECARQAVRYRDRGVVGFGL
                     GGPELAAPAKAFARAVAIARDGGLAFVPHGGEAGGPDSVRDLLELAPARIRHGIRAAED
                     DDLLAELRDRGVVLDVCPTSNLRTRVVESEAAHPLPRLVAAGLRCSVGTDDPAMFGTDL
                     GREHELAARLGLGPERAYAAGVAGALCDDATRDHLMAVGRRAYG"
     gene            complement(31889..34372)
                     /locus_tag="A4R25_RS17115"
     CDS             complement(31889..34372)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013288951.1"
                     /locus_tag="A4R25_RS17115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="WP_064447378.1"
                     /transl_table=11
                     /translation="MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVA
                     AKALESLGISLEGVRQQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIG
                     TEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGKEPAAAGAAPGEAAPS
                     TSLVLDQFGRNLTQAAREGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAV
                     VEGLSQKIIKGEVPETLKDKQLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIIL
                     FIDEIHTLVGAGAAEGAIDAASILKPMLARGELQTIGATTLDEYRKHLEKDAALERRFQ
                     PIQVGEPSLAHTIEILKGLRDRYEAHHRVSITDAALVAAATLADRYISDRFLPDKAIDL
                     IDEAGARMRIRRMTAPPDLRDFDERIAQVRRDKESAIDAQDFERAAQLRDTEKQLLGQK
                     AQREKEWKAGDLDVVSEVDDEQIAEVLGNWTGIPVYKLTEEETSRLLRMEDELHKRVIG
                     QEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELSKALAEFLFGSEDALIQ
                     LDMSEFHDRYTVSRLVGAPPGYVGYDEGGQLTEKVRRRPFSVVLFDEIEKAHPDVFNTL
                     LQILEDGRLTDGQGRIVDFKNTVIILTTNLGTRDVAKAVSLGFQASEDSESNYDRMKQK
                     VNDELKQHFRPEFLNRIDDTIVFHQLRQNEILSIVDIMIARIETQLRNKDMGLELTDNA
                     KKYLAKKGFDPVLGARPLRRTIQRDIEDNLSERILFNELPPGQIVVVDCEGDPDDTDTS
                     TLVFRAGKPVPTGQP"
     misc_feature    complement(34365..34380)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.0"
                     /tool="antismash"
     misc_feature    complement(34413..34431)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.28"
                     /tool="antismash"
     misc_feature    34416..34432
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.88"
                     /tool="antismash"
     misc_feature    34417..34435
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.75"
                     /tool="antismash"
     misc_feature    34550..34564
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 20.24"
                     /tool="antismash"
     misc_feature    complement(34559..34573)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.42"
                     /tool="antismash"
     misc_feature    complement(34660..34674)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.33"
                     /tool="antismash"
     gene            34745..36646
                     /locus_tag="A4R25_RS17120"
     CDS             34745..36646
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018745866.1"
                     /locus_tag="A4R25_RS17120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_231915560.1"
                     /transl_table=11
                     /translation="MESRACYRVDLLGPLRVRRKGHPVEPGPAKQRAVLSLLALRLGDS
                     VPVSEVEEAVWGGVVPPSARSLVHTYVARLRQVLEPEHPPRRRVRVIASTVTGYSLRAE
                     TVETDVARFRRCVAEAEKRIGEGCREEAFHLLGQALDLWRSPTLGELRSLLHDNIEVEA
                     LGAAWVATSHSYVGLGLRLGRAAAVLDTATRLARLEPLHEAIQADYLAVLGSSGHRTVA
                     LHRYADITERLRTELGVDPGEELRAVHRALVRPAGRPPVPRPAPAVPAARRRPGCGPIS
                     GPLHWRAGDIADLAALLAKYRAVTVTGAPGCGKSAVTLRAAHQAARVFTGGVLTVDTLD
                     LSDRRQLERRLARMLGGNGAEDPVELLRDQPTLVVLDNAEHLVDACAVVADRLLLACPD
                     VAVLTGSRQPLGLPYERVQRLHPLPVPQPGGWPSVLSNPAVALLAERAAQARPGFRLDR
                     RDAEVAVEICRRLDGLPLALEMAAACLATESLDGVLRKLEGPLDGLRPPAAGPESRHTS
                     LRAMLDRSVQRLDVAERCLFQRVALLPGVFDLAAAQRFWRPHPSGPTDVRVVLAALVDK
                     SLVMPVGTTGGRYRMLGLLRRLALETGTPGAVTSPAAELPLPLPRPLLPAGAAAVPD"
     misc_feature    34862..34864
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    36743..36759
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.34"
                     /tool="antismash"
     misc_feature    complement(36749..36758)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.85"
                     /tool="antismash"
     gene            36853..38052
                     /locus_tag="A4R25_RS17125"
     CDS             36853..38052
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788648.1"
                     /locus_tag="A4R25_RS17125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6004 family protein"
                     /protein_id="WP_030499571.1"
                     /transl_table=11
                     /translation="MSTRETYESLNLEPKPIRPHILAAATVVFGEDYYSGRRETINLSG
                     FVQLNKWPMPGFEHKVDENGYAQFATELISAPEVGIKGFSYELDDRIQVLSNPFLPNSG
                     HVRQIVPGKNFPAEFYIRRFGILESSTLRLAHRNVIDIYGVVDSVPPFKKPLTGPYLGK
                     PRGDGPFDVMAAPNVVKGTTLPEAWYPANDENQPVGITPNLFFAPSAGPCMSMLVDPSM
                     IMQTSLEGQIEVEVNGKTVRVDLAGDYRKAAGAEVLLFGPDKHDEGPGVLAQLARVAVV
                     GHSPELGGRVMLRASWPRVSGGTLGEGNEDSLSRLKFPGDLHIDAEFELVTPHETLYAA
                     NSVHVNGKMRGMEATGTELKLDGSDTALVTVDEQPKARLTGVNLVMRDALVGEHAAVNA
                     "
     misc_feature    complement(38089..38102)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.48"
                     /tool="antismash"
     gene            38181..39077
                     /locus_tag="A4R25_RS17130"
     CDS             38181..39077
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018745868.1"
                     /locus_tag="A4R25_RS17130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="WP_043325252.1"
                     /transl_table=11
                     /translation="MDQRLLLMHQMMLGDAPRLRAYDRALEEAVTPGDVVVDVGAGLLA
                     LSLLALRHGAEHVYAVEADPATAAAAARIIEANDLKGRLTLVTGDARTVRLPRKADVLV
                     SEMMGNLGPEEEMAEVLHVIARRHLRPGGRVVPRRLRTWLAAAEFADEGWGLWGGDFYG
                     YRLDPVQELVAPAAQLHFFQRPPKLLTEPTVVLDQALDGRSPSRQTLRQRLPVIAPGRL
                     HAVLGFFTADFTDDVTLSNFPSYPGCNWAVWVWPLRHTDVAEGDELSVALRRPARRDVR
                     AVTGWRLECGLSRQRRS"
     gene            39077..39718
                     /locus_tag="A4R25_RS17135"
     CDS             39077..39718
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018745869.1"
                     /locus_tag="A4R25_RS17135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_043325250.1"
                     /transl_table=11
                     /translation="MPFAVGTVRDIPVRGALKLCGLTWSAECLWFSEAVSSQIASLDPI
                     SGKVVRRLDCPGVRTDLTTIGGRLLQVAGDDRVLRLVDPEDGELLGEFGNPRPGNVLCG
                     LEATRHGLWLGYEDLRQVDLRDPDGFGLIDTFPVRQPIAGLTVSDSYLVYSDRDAATIN
                     LYDVAARREVAAYSVAGNPTGITWDGRRIWYCDFTTLQLRAIEVPGITKG"
     gene            39724..41010
                     /locus_tag="A4R25_RS17140"
     CDS             39724..41010
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018745870.1"
                     /locus_tag="A4R25_RS17140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="WP_064447380.1"
                     /transl_table=11
                     /translation="MATTRALLARSTRIGAVGAAHLLPVLPAALVKAVRGDRAAARRLL
                     YRRLTTLLMRLGPTFVKAGQVLGTRRDVLPAALCDELSVLQDRVDPMTPEQTSRALAEA
                     YGSETPAEFAEIDPTPVASGSVACVYRGRMPDGAEVALKLRRPGIESTMALDLALMRHG
                     ARVMARLPMLRGVPVREVVENMCGAVFGQLDFAREAENLRRLKENLAVVPRVRVPGVRD
                     DACRPRCLVMEFMPDLDVDVARSMSAAVRKRFAASAMTAIYHMLFVDGFVHCDMHPGNL
                     YFTRGAQVVVLDAGFSVQLTEELRRLFAEFFMNMSIGRGRYCAEIVVRSGTGLRPDADV
                     ETFLVRMADLVERSHGLPAREFSLIAFAAEMFDLQRRYGVHAAPELIFPLLSLLVIEGT
                     VRELDPDLDFQELAKPVLMRGLFGRRAAA"
     gene            41103..41807
                     /locus_tag="A4R25_RS17145"
     CDS             41103..41807
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788644.1"
                     /locus_tag="A4R25_RS17145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="crotonobetainyl-CoA--carnitine CoA-transferase"
                     /protein_id="WP_043325247.1"
                     /transl_table=11
                     /translation="MAQTGLAGKRSYHQYCGLASALDVLGERWTLLIIRELLMGPRRYS
                     ELLADLPGIGTNLLADRLKFLVDSGVLRQVDVHGTGGRLSYELTPTGQALRPMVLGLAH
                     WGLEFVGDLNAEDTVRPHWGFLAVEAMFQWDKISPIDESYQFQVDDEVFRIDVAGGVPR
                     VAKGPSDDPAMVATTDAATFVRIGAGRVTPLMAMVGGQLKLEGDIDAVLRCCELLGLDA
                     GAAPAAQTTSGH"
     misc_feature    complement(41841..41854)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.68"
                     /tool="antismash"
     misc_feature    41842..41856
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.6"
                     /tool="antismash"
     gene            42056..43333
                     /locus_tag="A4R25_RS17150"
     CDS             42056..43333
                     /NRPS_PKS="Domain: Aminotran_5 (32-402). E-value: 2.5e-129.
                     Score: 423.3. Matches aSDomain:
                     nrpspksdomains_A4R25_RS17150_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788643.1"
                     /locus_tag="A4R25_RS17150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_064447381.1"
                     /sec_met_domain="Aminotran_5 (E-value: 9.8e-129, bitscore:
                     424.1, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTVRHDPEALPRAVRDDFPLLARRAGDLVAYLDNAATTQKPRV
                     VLDAITDYYTGANSNVGRGYHRLGLESTERYEQARESVARAIGAAQPEEVLFTAGTTAA
                     VNLVADTAGQRVAGPGRRVVVTGMEHNSNLLPWRRLCDRTGATLTVVPAGPDGRVGADR
                     FAAALGPDTALVAVTHVSNVLGTVNPVREMTAAARRVGALVVVDGAQAVPHRPVDVRDL
                     DADFYCFSGHKAYGPMGVGVLHGRRDLLAGLPPYQVGGGTVKGVAADQPVRYLDGPARW
                     EAGTPYVAGAVGLAAALDYLRDLGWDAIRRHDRALVRHAVDVLAAIDRVRVVGDPAADP
                     SGIVSFVVDGIHPYDVGAHLDRHGVAVRCGVHCASTFLDEMGLLGTVRLSFGVYNTTAE
                     IDLVGELLAGVRPGPWTTDHPDVRFL"
     aSDomain        42152..43261
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R25_RS17150_Aminotran_5.1"
                     /evalue="2.50E-129"
                     /label="A4R25_RS17150_Aminotran_5.1"
                     /locus_tag="A4R25_RS17150"
                     /protein_end="402"
                     /protein_start="32"
                     /score="423.3"
                     /tool="antismash"
                     /translation="YLDNAATTQKPRVVLDAITDYYTGANSNVGRGYHRLGLESTERYE
                     QARESVARAIGAAQPEEVLFTAGTTAAVNLVADTAGQRVAGPGRRVVVTGMEHNSNLLP
                     WRRLCDRTGATLTVVPAGPDGRVGADRFAAALGPDTALVAVTHVSNVLGTVNPVREMTA
                     AARRVGALVVVDGAQAVPHRPVDVRDLDADFYCFSGHKAYGPMGVGVLHGRRDLLAGLP
                     PYQVGGGTVKGVAADQPVRYLDGPARWEAGTPYVAGAVGLAAALDYLRDLGWDAIRRHD
                     RALVRHAVDVLAAIDRVRVVGDPAADPSGIVSFVVDGIHPYDVGAHLDRHGVAVRCGVH
                     CASTFLDEMGLLGTVRLSFGVYNTTAEIDL"
     gene            43356..44495
                     /locus_tag="A4R25_RS17155"
     CDS             43356..44495
                     /NRPS_PKS="Domain: Aminotran_1_2 (51-197). E-value:
                     2.1e-09. Score: 28.9. Matches aSDomain:
                     nrpspksdomains_A4R25_RS17155_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168: O-succinylhomoserine sulfhydrylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018745873.1"
                     /locus_tag="A4R25_RS17155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PLP-dependent aspartate aminotransferase family
                     protein"
                     /protein_id="WP_064447382.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.1e-06,
                     bitscore: 22.8, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.5e-08, bitscore:
                     28.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFDTRLVHVGQRPVPGTGDVVPPIHLATTYDRTAQDPPRYFYAR
                     GEQPNREALEECLAALEDARHATVYTSGQAAATTALSLVPPGRLVLASDDVYGGTHQLL
                     AAAAERGVTVRPVDFADPAERDRALSECGPELAMVWLETPTNPLLKVADIAAVSDLAHR
                     HGALVVVDNTLAGPVLQRPLAHGADITLYSTTKSVAGHLDVLGGALVYQDEELHRRFLA
                     YRTVAGNAPGGFDCYLTHRGLKTLSLRTARQVENTRAVVAALLAEPSVATVSYPGLPTH
                     PQHAVAARQMTAPGALAAFEYRGDPAKLLDRVRLFTAAVSLGGVRSLIECPALMTHRPV
                     PPEVRRRLGLTDRLIRISPGIEDPADLVEDLVTALRDGA"
     misc_feature    43376..43390
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
     aSDomain        43509..43946
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4R25_RS17155_Aminotran_1_2.1"
                     /evalue="2.10E-09"
                     /label="A4R25_RS17155_Aminotran_1_2.1"
                     /locus_tag="A4R25_RS17155"
                     /protein_end="197"
                     /protein_start="51"
                     /score="28.9"
                     /tool="antismash"
                     /translation="EALEECLAALEDARHATVYTSGQAAATTALSLVPPGRLVLASDDV
                     YGGTHQLLAAAAERGVTVRPVDFADPAERDRALSECGPELAMVWLETPTNPLLKVADIA
                     AVSDLAHRHGALVVVDNTLAGPVLQRPLAHGADITLYSTTKS"
     gene            44534..45436
                     /locus_tag="A4R25_RS17160"
     CDS             44534..45436
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018745874.1"
                     /locus_tag="A4R25_RS17160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="WP_064447383.1"
                     /transl_table=11
                     /translation="MSAFTTGGAPVVLDGGLATELQRAGLPYQPPWWGTAALLADSRRR
                     VLRDVHERFLTAGAQVLTANTLRCNLRALRRAGLEDAGLGWMVHAAVGVALAARNTAGA
                     PGTRIAASMAPVEDCYRPDLVPADDELREEHRWLAVELVRAGVELVLVETMNTAREARI
                     AVEQVREVGARAWAAFVCDDQGRLLSGDSLVDAARAVRAAGAEVVLVNCTAPEATERCL
                     RALRDADDGPIGAYPNLEDRRDGAPGPRPLLDPAEFGDLVAGWAVEYRLAVAGGCCGAS
                     PAHIAALTARLNAPVAAVD"
ORIGIN
        1 cctccgcgcc gacgtgcacg aggttccagc cgggccgctg cggtgccacc accagcggga
       61 ggccccggcc gccgttgtcc actgcgacca gcagcggcgc gccggggcgg ccgggcggcg
      121 cgggcagcgc cacggcggtc gcggtggcgg cgacgatgac gaccgcgggc agcacgaccg
      181 cctgtccccg cagcaacgcc cggtccggct gccgtcggcg tcgcaggccg gcgcccaggc
      241 ccacggctcc ggccacggcg accgcaaggc agacccagcg tgccgggccg gcccatccgg
      301 ggccttccgg gccgagggcg gcgtggtcgg taccgagccg caccgcgccg gccgccgcct
      361 cggcggtgac ggcggcgagc atccagggcg ccgcccggtg ggcgacgcgc cgccgggccg
      421 agtccgcgcc gagcactgtg gcgacgccgc ccagcagcac cgcggcggcg agcccgtgcc
      481 cggcggcggc cgtcgcctcc gcgactgtcg cggtgggcag cgccagcagg ccggccccgg
      541 cggacacgag cagagccagg ggtacgccga ccgcgcgccg cccggcgcac ccgggcaggg
      601 cgaggcaggc cgccgcgagc acgagcgttc cggcggcggg ggcgtccccg cccaggccga
      661 gggtgagcag gtgcgcgacg gcggcggtca ccgccgtggc ggtgaggcgg cggggcgccg
      721 gggcggcgag cggtcgcagc agcacaagcc cggccgtggt ggccgtcgcg gcgagggcga
      781 gcagcgcggc gaacccggtg gcggccggcg cgacaccgcc gccgtccgcg gcgtgggccg
      841 gccccgccgc cagcagcgtg gccgccactg cggcgagggc cgcgccggtg agccgtccgg
      901 ccgatcgggg tacgccccgg cgaccgtcgg cggtacgcgg tgtcgcggtg cggtcgggca
      961 ctcgtgtctc ctcggctgtc acacgggtcg atcggccggg tcggcaaccg ggggatacgt
     1021 gttggcggcg taccagtcgc cgcggccccg cggcagcagg tcgagcacgt tccacaccgg
     1081 ggagagcagg tcgatgccgc gctcggtgcc gtcgacgaag ttggccggct ggctgtagaa
     1141 gtgccggacg ccgtcgccgt cgcggaccag cacgctgacc atcgggcgct ggtcgccgtt
     1201 cgggtgctcg gcgcgcaggt cggcgttgaa gtcggtgccg tggctggaga gcagccgcag
     1261 gccggcccag ccgcgccggg cgccccaggc gcgcagcttc tccgccgggg ccttgccgac
     1321 caccacgaac gcggtgtgct gccggaggtg gtgggcgacg ccgtggaacc cgtccaccca
     1381 catcgagcac atcgggcagg cggcgtcggc gtccgggtgg aacatcaggt ggtagacgag
     1441 gagcgtgcgg tgcgcgccga agagcgcgga cagccggacg gggcgcaacg ggccgggcgc
     1501 ggtcaggtcg gccggtccct cggtgagcgc gacgtcggcc accggcgcgc cgagcggcag
     1561 ctcccgccgg gcggcggcga cctgttcgat ctggtcacac aggcggcgtt cgacctcggc
     1621 gaggcgcagc cgcgcggcca cgtatccggc gtcggcgccg tccggccaca tcggcagcgc
     1681 cggcgcgctc gcgtcctcag tcatcctctc gtccttcctc gacccgcgct aacgccggcc
     1741 gttcgctata gaatatagaa gtgatcaacg ggtaggtgtc gacaaagggg gtacgcgcgt
     1801 gacggagacg accgcgccac cagggctgcc gcagcacggc cggttcgcca ccgccgaccc
     1861 cgacgccgac atccacgagt ggctcgccga ctggcgccgc caggccccga tgcgtgtgga
     1921 cgtcgtgccc ctggccggcc tgcgcggctg gcgccaggac gccgacaccg gagtcctggc
     1981 ccaccgcagc ggccggttct tccgggtgga agggctctcc gtcgaggtgc cgggcgcggc
     2041 cgtgccccgc tgggaccagc cggtgctgca ccagccggag gtgggcatcc tcgggctgct
     2101 cgcccgccgc gacggcgaca cgctgcgggt gctggtgcag gccaaggcgg agcccggcaa
     2161 ccaggacggc caccagctcg cgcccaccgt ccaggccacc cggagcaact ggaccggcgt
     2221 ccacggcggc cgcccggtgc cgttcctgca tcacttccgc gacccggacc cgcgccgggt
     2281 gctcgtggac gtccgccagt ccgagcacgg gtcctggttc ctgcgcaaac gcaaccgcaa
     2341 catggtggtc ctcaccgacg aggacatcgt gccgccgccc gggttccgct ggctcagcct
     2401 cgcccagctg caccggctcc tgcgccacga cgacctggtc aacatggaca tccgtaccgt
     2461 gctctcgtgc ctgccggcgg agctgacggc ccgggcggcc ggcccggccg gggacgcctt
     2521 cacggccgcg ctgcgccgct cctgccggcc cgggccgggc agccggcacc acaccggcga
     2581 gctgctgcac tggatcaccg acgtccgcag ccggacggag gtggacgccg accggacggc
     2641 gctgcgcgga caggcggcgt ggcatctcgg cgaggtctcc ctgcgacacg acagtgggct
     2701 gttcttcgag gtcatcggcg tggacgtgga cgccgagggg cgcgaggtgg cgagctggtc
     2761 gcagccgatg ctgcggccct gcggccaggg ggtggtggcg ttcctggcca cccgtctcga
     2821 cggtgtgctg cacgtgctgg cgcacgcccg ggtcgaaccg ggcttcgtcg acgtggtgga
     2881 actggcgccg acggtccagt gcacgcccgc cacgctcgac tacctgcccg ccgccgcgcg
     2941 tccgcccttc ctggaccagg tgctcggcgc gccgccggag cgggtccggt tccgcgcgct
     3001 cctctccgag gagggcggcc ggctctaccg ggcccgtagc agctatctgg tggtggagac
     3061 cgacgacgtc gacctggaga gcgaccagta ccgctgggtg acgctgcacc agctctcgga
     3121 actgctgcgg cacagcaact acgtgaacgt ctcggcccgc agcctgatcg cctgcctgcg
     3181 cgggctgctg gacgccggct gagcgggcgg accgggtcac gcccggtccg cccgccgcga
     3241 cggcggtcag tcgccgaagc cggtcgggtg ggcgtcgccg accgcgttga gcagcacacc
     3301 ctgctccagc agcgccttgc aggcgcagag caccatggtg aacccgccca tcgagtcgat
     3361 cgccttcgcc acggcctggt cggcgctgcc ggcgaagccg gtctcggtga cccggaccag
     3421 cgtcgtgtca ccctcgcccg gcaggaaccg ccattcgagc tgggtggggg actccgggtc
     3481 ccactcggcc aggatgcggc tgttcttctc gacgtccttg accgtgacga cggtggagac
     3541 gccgtacatc tcccagtccc aggtgacggt ggcgccgggt tcgagccggc cgctgctctt
     3601 ggtgaaccag aacttggtgg tcaccgccgg gtccgcgaac gcctcgaaga cctcggcggc
     3661 gggcctgcgg atgagcatct gcgcggtgac ggcaggcggt tgagtcaaac ggtcgctgtc
     3721 cacggggtag ccgtgttccc ttctcgtgtc atcggcactg cgtacaaacg gtggcggggt
     3781 caggcccgcc ggcggtacag gaacatggag agcggggcga agacggccac cagcgccgcg
     3841 cagccgacca gcgccgcgcc tacctcaccg gcggtcgccg tgccgtgggc caggccgcgc
     3901 gcggcggtga ccgtcaacgc gaacgggttc aggccgacca cggcctgcag ccagccggga
     3961 agcgtctcct gcggcacgaa gaagttgctg acgaacgaca ccgggaagac gatcgcctgg
     4021 caggcgctca gcgcggcggt cggtgacttc agggcgagcc cgaagaccac gtacacccag
     4081 gagaaggaga agacgaagac cagggtgatc aggatcgtgg cgaggacgcc gagcacgcca
     4141 ccgtcgggcc ggaagccgac cgcgagcccg accgccacgg cgaccgcgca gccgacgacg
     4201 tagagcacgt tgttgccgag cagggtgccg acgatcgcgg cgggccgcca gatggccagc
     4261 gcgcggaagc ggtcggtcac ctcccgggag ttgtccaggt tgaccaccgc gccgatccgc
     4321 atgctgatca tgatcccggt gaacaccacg atgcccggga tgtagaactg catgtagctc
     4381 gacgtcgaac cggccagcgc gccgccgaac aggaagccga agacgagcgt gaacatgacc
     4441 ggcacgccga gcgcctcgag gatctgcgtc gggtcgcggc gtaccttctg caccgcccgc
     4501 cacgcgaagg tcagcgtgga cgacagcgcg ccgggacgtg ccggccgcgc cgcggacggc
     4561 gccgaggcgc cacggccggt gccggtctcc accatgctgc tcacgccgcc tcctcggtct
     4621 cggtccgcga gccgtccgcc cggtgcccgg tgagggcgag gaacacctgg tccagggtgg
     4681 cgtggccgaa ggcgtactcg gccaggccga cgccggcccc ggtgagggcg gcgagcgccc
     4741 gggtggcctc ctcctcggcc gcgacctgcg cggtcagctc catccggtcg gcgccggcgt
     4801 gcaccgccgt gcccagcgcc tccgccagca tccgctcggc cgtctcccgc tgcccggcgt
     4861 cgcgcaaccg cacccgcagc acgctcgcac cgatcgaccg cttcagctcc accggcgtgc
     4921 cctcggcgat gacccggccg tggtcgacga ccgcgatccg gtcggcgagc tggtcggcct
     4981 cgtcgagata ctgcgtggtg agcaggacgg tggcgccctc gccgaccatg ccccggacga
     5041 gttcccacac ctggttgcgg ctgtgcgggt ccagcccggt ggtcggctcg tcgaggaaca
     5101 tcaggtcggg tgtcacgatc atgctgctgg cgatgtcgag ccgacggcgc atgccgccgg
     5161 agtaggtccg caccagccgg gcggcggcct ccttcaggcc gaacgtggcg agcagttcct
     5221 cggcgcggcg gcgggccgcg ctccaggaga agccgcgtag ccgggagagc aggacgagat
     5281 tgtcccggcc ggacagttcc tcgtcgaccg acgagtattg cccggtcagc ccgatccggt
     5341 cgcggatcgc cccggcctcg cgcaccacgt cgtggccgag cacgcggacc tcgccgctgt
     5401 cgggcgggac gagcgtggcg agggtgcgga cgatcgtcgt cttcccggcg ccgttggggc
     5461 cgagcacgcc gaacacgctt ccggccgaca cgcgcagatc gatcccgtcg agcgcgcgca
     5521 cctcgccgta ggatttgcgc aatcgtgtga tctcgatggc gggagtgtcg gtctgctgtg
     5581 cggacaaccc agccgtacgc gacattgtgt tcacaaacat atagtagcag gacgtttcgc
     5641 tccggtcacg cctcttgatc cgcgcgtcgc gcgcgttccg ccaccacgtg atcgtcgcat
     5701 ggacacccgt cggtcgatag ctataacatt ctcaagcagc aacttgccgc cgagagtgga
     5761 ggagcggacg tgtccacacg cgagctgacc gaagtcgacg aggtagcgga gatctacgac
     5821 gacggcgcct gggccgtcga ggtgctcggc ggaaacatcc acttcggatg gtgggaggac
     5881 gacgacgacc gcacgccctt cctggaggcc atcaaccggt tcaccgacat cgtcggcgac
     5941 cgcctcggcc tgcgccccgg cgatcggctg ctggacgtcg gctgcggcgc cggcgagccg
     6001 gccatccggc tcggccagcg cagcgacgcc gacatcaccg gcatcaccaa cagcgccgag
     6061 cacctcaagc gggcccggga acgggtcaac gagtccgggc tgcgcggcca ggtccgcttc
     6121 gagctcggcg acgccgccgc gctgagctac ccggacgcct ccttcgacaa ggtgctcgcc
     6181 ttcgagtccc tggtgcacgc gcaggaccgc cggcagtggc tcgccgagat ccgccgcgta
     6241 ctcaagcccg gcggccggct cgtgctcacc gacctcgccg aggacgcccc gctcaccgag
     6301 cgggaccggc agatcctcac cgacttcacc ctcgccccgc ccggcccgcc gatggccgcg
     6361 ttcgacctgg tccgcgacgc cggattcgtg gtggacgagt tcctcagctg cggcgacaag
     6421 atcagccgtt cgttccccgc gtaccacgag cgggtgcagc agcggcgcga cacgctcgcc
     6481 gccgcgcacg gcgccgagaa gatcgatgcc ttcctcgccg agatgccggc cgtgctcgac
     6541 gtcctgcgca ccaaggtcgg ctgcgtcgtc atcgccgccc acaagccgcg ctgacccgcc
     6601 cggcaccggt gaccggaagg agcaggcaga tgaccgcccc cgccgtcacc ggctgccgga
     6661 tctgcggcgg cccggtgacc gagatgctcg acctcggccg ccagcccctc tccgacgcgt
     6721 tccccctccc ggccgacctc gacggcgagt tcttctaccg cctcgcggtg ggccggtgcg
     6781 ccgactgcac gatggtccag ctcgtcgagg aggtgccgcg cgagcggatg ttccaccacg
     6841 actacccgta ccgctcgtcg ctgtcgtcgg tgatgcgcgc gcacttcacc ggcaccggcc
     6901 gggaactgct cgccaccgag ctgacccggc ccggcgcgtt ctgcgtcgag ctgggctgca
     6961 acgacggggt gatgctgcgg accgtggccg cggccggcgt acgccacctc ggcttcgagc
     7021 cgtccgccgg ggtggccgag ctggcccgtg ggcagggcgt acgggtgcgt accgacttct
     7081 tcgaggagga gaccgccgcc gacgtgctcg ccaccgacgg gccggccgac gtcatctacg
     7141 ccgccaacac gatctgccac ctgccctacc tggactcggt gctgcgcggc gcgcggctgc
     7201 tgctcgcccc cggcggcgtc ctcgtcttcg aggacccgta cctcggcgac atcctcgccc
     7261 ggaccgcctt cgaccagatc tacgacgagc acttctacta cttcaccgcc cactcggtac
     7321 gggccgccgc ggcccgcttc gggctggagc tcgtggacgt gcggcggctc ccggtgcacg
     7381 gcggcgaggt gcgctacacg ctcgcccgcg ccggggcgcg taccccgtcc ccggccgtcg
     7441 ccgacctgct gcgccaggaa cgggagcagg gagtgaccgg ggaggcggcg ctgcgccggt
     7501 tcgccgccgc cgtcgcgcgt acccggtccg agctggtcgc gctgctgcgc tcgctgagag
     7561 aggagggccg caccgtcgcg gcctacgggg ccaccgcgaa gagcgccacc gtcaccaact
     7621 actgcgggct cgggccggag ctgatctcgt acgtctgcga caccaccccg gccaagcagg
     7681 gccggctgac cccgggcgcg cacatcccgg tccgcccgcc cgaggcattc gccgacccct
     7741 acccggacta cgcggtgctc ttcgcctgga accacgccga ggagatcatg gcgaaggaga
     7801 ccggcttccg ggccgccggc ggccggtgga tccactacgt gcccaccgtg cgcgtacggt
     7861 gacggcatcg gtggcgcgcg gcttctaccg cgccggatac ccggagatct acgacctggt
     7921 gatgcggcac cggggccgcg accacatcgc cgaggccgcc acgctcgccc ggacggtccg
     7981 gcgccggaac ccggccgccg cctcgctgct cgacgtggcc tgcggtaccg ggctgcacct
     8041 ggagcacctg cggacccact tcgccccggt gaccggcgtg gacctgtccg gggagatgct
     8101 ggcccgagcc ggcgcccggg tgccggacgt ggccctgcac gagggcgaca tgcgcgacct
     8161 ggatctggcc gacaccttcg acgtggtggt ctgcctcttc gcggtgccgc acctgcgcgg
     8221 cgccgccgaa ctggaccgga ccgtcgcgcg gctggccgcc cacctgacgc cgggcggcgt
     8281 gctggcggtc gagccctggt acacgccgga gacgttcgtc cccggctacg tggcccgcga
     8341 catggtgcag gagcaggacc gggtggtggt ccggctgtcc cactcgacgt ggctcgacga
     8401 cgcgcgcgac cggatccgga tgacagtgca ccaggcgtac gccgacccgg aggccggcat
     8461 ccggcacgac accgcgacga ccgatctgac gctgttccgg ccgcagcact tcgccgccgc
     8521 gttcgcccgg gccgggctcg ccgccgcgca cgtcacggcg ccgccgttcc ggtggggcct
     8581 gtggatcgcc cggcccgcag gtgcgcggtg accggcgacc ggccacgcgc ggtcgtgctc
     8641 ggcggcaccg ggttcgtcgg cgcccatgtc gcggacgcct tcgccgacgc cggccacgac
     8701 gtgctcacgg tggcccgccg cgccccggcc ggcgaccggc accggttcac cgcgctcgac
     8761 ctcggcggca ccggtccggg gacgctggcg cggctgctgg acgccgagga cccggtcgcc
     8821 gtggtcgact ccaccggcag cagctgggga ctggaccccg gccggatggc ggagcgctgc
     8881 acccggctca gcgcgctgct gctcgacgcg ctgcgccgcg ccgcctgccg cccccggctg
     8941 gtccatctcg gctcggtgct ggagtacggg cagccggtcg cgccggccga tccgcgccgt
     9001 acgcccgcgc cggacaccgc gtacggccgg gcgaaactgg ccgcgacccg ggccgtactg
     9061 gcggcagccg acgccggtga ggtcgacgcg gtggtgctgc ggctggtgaa cgcgctcggc
     9121 ccggggctgc ccgcgaccag cctgctgggc cgggtcgccg ccgcgctggc gccggccgcg
     9181 cgggccggcg tcgccgcgcg ggtgacgctc gccccgctgg aggcccggcg tgacttcgtc
     9241 gacgtccggg acgccgccga ggccgtgctg gccgccgccg ggcgcccggt gaccggccgc
     9301 gtcctcgaca tcggccgcgg cgaggcggtg ccggtgcgga cgctggtccg gctcctggtg
     9361 caggtcagcg gggtgcaggc gacagtggtg gagcgtgccg gcccggccgg ctggcgggcc
     9421 gggacccggt ggtcgtgcgt cgacccggcg cccgccgcgg cggccctcgg ctggcggccg
     9481 cgccgcgacc tgcgccgggc ggtcaccgac ttctggcacg acgagctgcg tcgctactcc
     9541 ggcgacgggg agccggcggc ggcggggccg ccgcgtcagc gggcgccgta gcgccggcgg
     9601 ggaatcgaca ggtggcgcga ccggcgtcac cggctcggcg gtacggcgtc ggccgtgccg
     9661 ccgcgacgac agggagggca ggagtcatgc gcgtactgtt catgccgggt ccggccatcg
     9721 gccacgcgtt cccgctggta ccgctcgggt gggcgttccg cgccgccggg cacgaggtcg
     9781 tcttcgtcac cgccggtgac gcgctggcgg tggcccgggc cgggctgccg gtcctggacg
     9841 ccgtgcccgg acgcaccacc tcggacatgc aggcgcagtt catccgcgac gtgccgcgcc
     9901 tcttcgagcc gatcggcgcc gacccgatcg cggagatgga ggaacgcaag ccgtacatcg
     9961 tctcggcctg ggatccgttc gtcgacgccc acgtcgcgct cggcgagtgg gtccagccgg
    10021 acctggtggt gtacgacccg atcttcgcgg tcggcccggt cgtcgccgcc cggctgaagg
    10081 tgccggcggt cgcgcacagc ctcgggctgg cccggttcac ccccgacctg ctgcgcgagc
    10141 tgcccggcgc ggtggcgatg cgccggcacg gggtgacgct gcccgagggc atccggaccg
    10201 tcgacatcgc cccgcccagc ctggtcgagg gcgggccggc cgacatctcc atgcgctacg
    10261 tgccgtacaa cggcggcggg gtgctgcccg agtggctgcg ggagccggtc gcgcggcccc
    10321 ggatcgccgt cacgttcggc acgctcggcg ggccggaccg gttcgccgcc ggcatcgcgc
    10381 gggtgctcgc cgccgcgccc gggctggacg ccgagttcgt gctggcgatc ggggagtcgg
    10441 ccgctccgcc cgacctgccg ccgaacgtgc ggaccaccgg ctgggtgccg ctgaaccagt
    10501 tgctgcgcgg ctgcgccgcc gcgatccacc acggcggcga cggcacgacg ctgacctgcg
    10561 ccgcgctcgg cgtccgccag ctggtgctgc ccggctcgcc ggacgagctg gtcaccggcg
    10621 agctgctgcg cgcccggggg ctggcgcacg tgctgggctc ggtggacgag ctggacgccg
    10681 ccgcgatcgg ccggctgctc accgacgcgg agctgggccg ggtgaccggc gaggtgcggg
    10741 ccgagatcgc ggcgctgccg tccccggccg aggtggtgcc ccggctgacc gcggcggtgt
    10801 gagcccggcg gcgggcggct cgtcgccgcc cgccgccggt tgcggtcagc gcagttgcgc
    10861 gtcggccacc gcgaagagca gcccgtgcgg attcgccttg ccggtgtcgc cgtgcggcca
    10921 gctcgtccgg tcgaagctca cgcagcgccg gccggtgtgc tcgtcgcgga acgcgcggtc
    10981 ctcggtgagc cggcccgccg ggtcgaccag cgccatgcag atccgggcgt caccgtcgag
    11041 tccggtgggc gccacgaagt agttcgaggt gaccacccgg gagacctggt cggtctggcg
    11101 gaagtgcttc ccgcccgcca ccggccggaa cgtgtccatc gcgccccagt gcggcccacc
    11161 gagtgtggtg tccacgatgg gcagcgcgct gaccagagcg ggacagtccg gctcggcacc
    11221 gccgcgtacg gtctccgcga tcgtgtcgat ccggcacgag gtccggctgc cggcggcgag
    11281 gagccggcgg atgtccagca cgtacaccat gccggactcg gcgttgacgg ccggtgagtt
    11341 gttgccgccg aacatcaccg tgtggaacag gaaacggtcg tccgggctca ccatgagcca
    11401 gctgccgccg tcggccgcgc tggtcggggt gtcgcgcggg tagatccggc ggaaggcggt
    11461 cgcgtcgtcg aacacctgcc gccaggtcag ctcccgcttg gtgatgtccg gcgtgtagta
    11521 gaccgcgccc atcccggtgg ccacgaacgc tcccttgtgc cggggctggt gcgtcaccgc
    11581 gggctccatg gccagcagac cctcgcggct gtactcgtcg tcgacccggg gcccgtcggg
    11641 caggtaggac agggagagca ggcggggccg gttccggtcg ctgatgtcgt acgtgcggac
    11701 cgtgcggcgc tgcaggttgg ggtcggtcac caggccggcg acgacgtgcc gcacctcgac
    11761 gaagtcgctg gtgaccagcc ggttcaggtc ctcgcgcagc gcgatgccgt gcgggttggc
    11821 gcaggtcggc accggcagcg cgggctggtt ggggcaggag accgggtcct cggcggtctt
    11881 cttcgccgcc ggcatctcgg ccagcacccg gccgtcggcg ccgagccgga ccacctcgcc
    11941 gggggagccg gcgaagccgt tgcccacgcg ggtctgcccg tcggagtagg tgcagggccc
    12001 ggcgacgtcg ggcccgccca tgtacgaccc gtacgcggtg ccgtcgcgca ggacggtgaa
    12061 cgcgtccggc accgagccgc acggggtgtc gtgcggcagc gtcacgccgc tgagcgagac
    12121 ccggggcagc cggctgacgt cgaagacgta gacggtgtcg ctgagcaggc cgcccgcgta
    12181 caccttgtcg cccttgcgcc aggtgtactg catgtggtgc ggctcgttgc cgaagaccga
    12241 gtcgacggtg acggtgttcg ccacccggcc gtagtcgggg gagccggggg tggcgtccac
    12301 gacggcgagg aagtcggggt cgggcctgcc gtcggggccg ggcgcggcgt caccggtcca
    12361 gaccagcagc cactggcggg cgggcgcgcc cggacgttcg gcggcctgag ccgtgcgggt
    12421 gaggtggttg gtgatccggt acggctggcc gtcgctgccg gtcaccgtcg aggtgacccg
    12481 ccgcacggac gccccggccg cggccggggg tggcaccagg ccgctgctga cggcgacgag
    12541 cgcgatcact ccgatgtggg cggcccgccg gagcggaccg cgcagttgtg gacggggcat
    12601 ggacgtcctc ctggtcacgt gcgggattga ggccggaaca tgccaggcgt cgcggtcgag
    12661 ggggacggag aagtgccagg gagcggcgcc cgcggcagcg agcctactat ccgaattgca
    12721 actgtcaatt gacgggaagt cgactgcagg gagatccact gcgcgcaatt tccatcgatt
    12781 gccggaggtg ccgcgatggt cgacagtggc cgatgtcggg gcaggtcagc tcggtcctga
    12841 gggcttgccg ggaaaggctg ttcgcgcgcc ccgcagggtt ggtgccaagt ccgcggcgac
    12901 ggcgtcgcgg cccgggtgat tccgtccgtt cgggccagtg gccgggagcc gcctgtaccg
    12961 acgtcggttg acgaacgtgt agctagccga tggggcggcg actaggatgc ggggtggtga
    13021 tgccggggtg aggcgccgcg gcgacgacgc tcccggggag gtccgccgcc atgaccatcg
    13081 gagtctggaa ctacctggcc gagtacgaga gcgagcggga ggacgtcctc ggcgcggtgg
    13141 accaggtctt ctcctccggc cggctggtgc tcggtgagag cgtgcgcggc ttcgagcggg
    13201 agttcgccgc ctaccacggc gtgccgcact gcgtcggggt ggccaacggc accgacgcca
    13261 tctcgctggc cctctgggcg ctgggcgtac gccccggcga cgaggtggtc accgtcgcca
    13321 acacggccgc gccgaccgtg ctcgccatcg acgcggtggg cgcggtgccg gtcttcgtcg
    13381 acgtggacga ggcgacctgc ctgatgcgcg tcgaccgggt cgccgacgtg atcacgccgc
    13441 gtacccgggt gctgctcccg gtgcacctct acgggcagtg cgtcgagatg gcgccgctgc
    13501 gggcgctcgc cgccgcgcac ggcctcgcgg tgctggagga ctgcgcgcag gcgcacggcg
    13561 cgcgccacca cggccgcgtg gccgggtcgc tcggtgacgc cgccgccttc tccttctatc
    13621 cgaccaaggt gctcggcgcg tacggcgacg gcggcgcgac gatcaccgcc gacccggacg
    13681 tggagcggcg cctgcgccgg ctgcggtact acgggatgga ggaccgctac tacgtcgagg
    13741 agacgcccgg ccgcaacagc cgcctggacg aggtgcaggc ggagatcctg cgccgcaagc
    13801 tgcggcggct ggaccgctac gtcgccgccc gccgcgcgat cgcccgccgc tacgacgagg
    13861 ggctcgccgg caccggcctg ggcctgcccg tcaccgcgcc cggcaacgag cacgtctact
    13921 acctctacgt ggtgcggcac ccgcggcgcg acgagatcct ggcggcgctg cgtcgccacg
    13981 gcatcgagct gaacgtcagc taccgctggc cggtgcacac catgcgcggc ttcgcccacc
    14041 tcggctacac cgaggggtca ctgccggtga ccgagcggct ggccggggag atcttctcgc
    14101 tgccgatgta cccgtcgctg gacgagggcg cgcaggcccg ggtgatcgac gcgctgcgca
    14161 cgattctgcg ggcctggtga cgctccgaag cgggcaccgc aagaattgag aatcatatag
    14221 caaactgcgc tcgcgcggat ctaccatctc ggcatggagc cttccacgtt cagcaccccg
    14281 gtcggcgact tcgccgacct ccgtgacgac ttcctgcggc tcaccaccga gatcggctgg
    14341 tgcaccgtcg ccactgtgga cggacgcgac cggccgcgca gccggatcat gcacgtctcc
    14401 tgggaggtcg gcgacgccgg cccgaccggc tgggtcagca cctcccgcac cccggtcaag
    14461 accgcccacc tggcccgcaa cccgtacgtc tcgtgcagct actggacacc cgcgcacgac
    14521 gccgtcttcg tcgactgcca cgccacctgg ctggagccgg gcgacaccaa acgccacgtc
    14581 tgggacctcg tcgccgccga ggcgacccag cgcggcttcg acccgtacgc ggtctggccc
    14641 gacggccccg ccgacgccgg cttcgaggtg ctccagttcg acccctggcg ggtccagatc
    14701 acccttcagg acctggccaa cggccagacc atcggctcgt cgcgggtctg gcacgccgcc
    14761 gggcggcccg cgtccaccgg cgcgctgctc tcccgctgat cccgaccggg ccgccgccgc
    14821 acgacggacc ggcccgtcac cgccgacgcg gcgagccgcg cggcccgaca ccgagggaac
    14881 gcaccatgac caccaccctg cgcacacccg cgtcggcgcc cggccgcctg cccgtgctcg
    14941 ggcacggcct gcagatgaaa cgacgacccg ccgagttcct gctcgaactc cagtccggcg
    15001 agccggtcgt caccatcgcg ctcggcaagc gcccggcgta cgtggtgaac gacccgaccc
    15061 tgatgcggga gctgctgcgc gacggcgaca ccttcgtccg gggcggcccg atgaccgagc
    15121 gcttccggtc catgttcggc aacggcctgg gcatctccga gggcgagttc caccgccggc
    15181 agcgggcgct gatccagccc gccttccacc gcaacaaggt catccactac accgagctga
    15241 tgagccggac ggtcgccggc aagctcgact cctggcgcga cggccagcgc ctcgcggtcg
    15301 agaaggagat ggacgagctg gccctcacca acgtcgtcga ggtcgtcttc gccggtgacc
    15361 gaagcctgga ccgagcccgg ttcatggccg cgaccaccac cgtcctgggc ggactgttcc
    15421 gccggatcac cgacgtgacg ggcgtgctga cccgcctgcc cacccaggcc aaccgcgact
    15481 acgacaccgc ggccgaatac ctgcgggcga ccatccgccg ggtcatcgcc gagtaccgcg
    15541 cggccggcac cgaccacggc gacctgctgt cgatgatgct cttcgcccgc gacgaggacg
    15601 gccggcccgc gatgagcgac gagcaggtcc acgacgaggt gatgacgttc ttcatcgccg
    15661 gcagcaacac catcgccaac acgctctgct gggcgctgca ccacgtcggc gcggaccccg
    15721 aggtgcagcg gcggctgcac gccgaggtcg accgggtgct cgacggacgg gccgccggct
    15781 acgccgacgt gccggcgctg gagtacaccc gccaggtgct ctccgagacg ctacggctgc
    15841 gcacccaggg cctgttcaac aaccgggtca ccgcccgcga cgccgaactg ggcggctacc
    15901 tgatcccggc cggctcggac gtgctctaca gcttccacgc cgtgcaccac aacccgcgca
    15961 tctaccccga gcccgagctc ttcgacccgg accggtggct gccggaacgg gcccggacgc
    16021 tgccccgcgg cgcgttcatg ccgttcgcca ccggcgtgca cggctgcatc ggcgaccagt
    16081 tcgcctggac cgagatgatc gtctcgctgg ccagcatcgc cgcccgctgg cggctggagc
    16141 cggtgcccgg ccacgagccg aagcccgtgc cggccatgac catgcccgtc gacgcgctgc
    16201 cgatgaccgc gcgccgccgt acccgctgaa cgaccgacgc ccggccaccg gcccacacgg
    16261 accggcggcc gggcgtccgg ccgctcagag ctccccggcg atcacgttgc ccggcgcgtc
    16321 cgggtcggcg ctgaggtaga actcgtgcgc cgcccgaccg tactcctcgc tggtgaggta
    16381 gccgtcccgg tcggtgtcga gccggtcgaa gatccgttgc gtgtcctcgg agcgcatgcc
    16441 gctcttgctc tgtgccgcga acatctccgc gtggttgatg cgcccgtccc ggtccgcgtc
    16501 ggccacgtcg aacacggcca ggctgaacgg caccgccgcg ttcgtcacga actccgggaa
    16561 ctccggcttg tcggcccacg ccacccactc ggcgaccgtc acccgcttct cgccgtcggg
    16621 cccgtcgctg ccgcgcatcc cgcgccacat ccgggccgcc gcgccgtgga tccgccgcca
    16681 gcccggcgag tacggcgcca cgccgtacgt gtcgcaccag atctgggcca tcgcggtgat
    16741 gtccagcccg tcgatgacgc cgtccccgtc ggcgtcgtac gaggcgaaga ccttctccag
    16801 cttgcggcgt tgcagttcgg tggtcatctc ggtcccttct tcgcgtggaa tctgtcagtg
    16861 cggggcgacc gcgcggacgg tgagcgcggt cgaggtcagg tcgaccagtc cgtccgggcc
    16921 ggcgcgtccc tcggcggcgg cggccacctc ggcccagagc gcgtcccgcc cggccggatc
    16981 gagcgcctcg acccggcggc gtaccggtgg cggcgccacc gcccgggtga accgcgcgta
    17041 ctcggccggg tcgtggaacc ggaacgggac cgggtactcc tcgactgtca cgtcccgcag
    17101 gccggcgtcg gtcagcccgg ccgccagcgc ctccggatcg cacaggcggt acgggccggg
    17161 ggcgtccggt ggcccggacg gcaggtccag ccggcgcgcg agcacgccgt acccgagcga
    17221 catcagcggc acccgcggcg gtggcgccca caccgccgcg gcgagcacgc cgcccgggac
    17281 gagcagccgg gcgatccggc cgaacgcggc gccggggtcg acggcgaaca tcaggccgag
    17341 ccggctgagc accacgtcga acgcgtgcgg cggcagctcc accgtctcca ggtcggcgac
    17401 gaggaagttg acgttgcgcc ggccctcggc ccggcggcgg gccacggcga gcatggcggg
    17461 ggagaggtcg acgccggtga ccgtgccggc cgggccgacg atgtcggcgg cgctgagcgc
    17521 cggctccccc ggaccggtcg cgacgtccag gacgcggtgc cccggccgta cgccacccag
    17581 ggccagcagc cgcgcggtga gcgccgcgcc gccccgctcg aaggtctccc actcgcgggt
    17641 ccagccgtcg ctgacggcgt cccaggtccg ccgctgttcg gccttcaccg cggcggcatc
    17701 tgtcgatacg gacatcgctt tccctcctgt ggtccgtcag gtcacccgcc cggccgggcc
    17761 ggttcgcggt cggcaggccg gtcgccggcg tcctccggct cccgcagcac ccaggcccgc
    17821 cgtcgcccgc ccggccccgg accggccgac gagggcgtgc cgccggcggg ccggtcacgc
    17881 cgtccccgcg ccatgagcac gagcaggacc gctccggtga ccaccggcgc cagcagcagg
    17941 gccaggccgg ccgctccgcc cgtacccccg tggtggccgc ccccggcgga cccgtccggc
    18001 ggcgcggtgg ccggcgggga cgcggccgga gcggcccgcg gcggcgcgcc gagcccggcg
    18061 gcgacggtga acgggaccac gccggtggcg gtctgcccgg tggcgagctg ggcgtggtaa
    18121 ccgacccggt agcgcccgtc acccacgacc gtcaccggca cctcgacgcc gttgtcgcgg
    18181 tagcgcggcg cgcccgtcgc gccgaacgcg ccgcccgggc cgatcaacca gacatgggtc
    18241 cgctcggcgt cgagcgggcc gttgaaggtg agcgtcaccg ccgccggcgc cgtggtcagc
    18301 cgggcgccgg ccggcgggtc ggtggtcacc aaccgcgccg gccgcagctg cgccgccagg
    18361 gtcagcccgg ccaggccgag cgcgagcagc gtgagcagac ccgccgccag ccacctcagc
    18421 cccggcccgc gcctcaccgg acttcggcca cccggcggca actgcaccgc atccgggcca
    18481 gttcgtcggc gagcggcgtg cggtgcaggt acatcgccac caccatcggc aggaacacca
    18541 ccgcgttgta gaacaggtgc agctccaccc ggggcgccac cagttgcagc aggctcgtcg
    18601 gcaccggctg cccggccagg ttgctgccgg tcagcgactg caccagcagc agcaggtgct
    18661 ccaggtggtg ccacacctgg atcagcagcg ccgccatcca ccaggtccgg gcgcggccga
    18721 cgaagccgcc gcgcagcagc cagaaaccgg cgagcatgac cagcgcgtac ccgtagtgca
    18781 gccactcgct ctccaccagc cacgggaacg gcatgccgag tacgccccgg gcctccggcc
    18841 gggaccagcc gaacacccag atctgcgcgg cctgcaccag gtgctcggcc cagtgggcga
    18901 tgacgacgac gaggaagatc tgcagggccg cccggtgccg gctgccgttc agatcgagcc
    18961 ccgaagcgcc ggcgtcgcgc ttgtccgaca gggtcactgc gcctccttca ggagcggttg
    19021 gacgtgccgg cggccggcgg ccgggtggga gttcccgtac ctgtcgaacc ggcctcgccg
    19081 gaagatcagg gcgtcgctgt cggcagccgt gcgcgcggcc accagccggc ccaccacgat
    19141 cacgtggtcg ccgccgtcgt ggcagcgcca cggccggcac tccagccagg ccagcgcccc
    19201 gtgcagcagc ggcgcgccgg tccgctcgcc cggcgaccag ccgacagcgg cgaactgcgc
    19261 gcgcccgggc cgccggcgcc ggtcggcgaa gtgccgggcc aggcgctcct gccccccggc
    19321 caggacggag atgccgaacc cgtccgcgtc ggacagacag gcggacatca ggctgtcccg
    19381 gctcacgcag agcagcacca gcggcgggtc cagcgagacc gaggtgaacg agttcgccgt
    19441 catcccgtgc ggcagcggac caccgaccgt cagcaccgtc acgccggtga cgaactcgcc
    19501 gagcaccgta cgcagcgcgg cggtggccgg cggcgcgtcc acggcgcgct caggcacggc
    19561 cggccacccc ctcggccgcc cggtacggcg ccagcgcccg caccagcggc gtcggcacgc
    19621 gggtcggcac cacctgcccg gcgacctccc gcatgcaggc gatccgctgg tgcccccggg
    19681 ccaccgggac cagcccgccc gggccgtcgc gcaggtagtc gaaggccagg ccgagctgcg
    19741 tctgggtcag ctcggtcagg ctcatccgga tgcgcagctc gtcgaacgcg tcgagctcgg
    19801 cgaggtactc gcagtccacc cgcagcgtga acagcttcag cccggcgcgc aggtcgtcga
    19861 ccaccgccgg ggcgtgctcg cgcaggaaca tctcccggca gcggccctgc cagcgcaggt
    19921 agttgacgta gtagacgttg ccgacgaggt tcgtctcctc gaacccgacc acgtggcggt
    19981 actcgtacca ggcggacatg tcacaccccc gtcgcggtga ggacggcgac gaccaccggc
    20041 tgtggctcgc cggtcagacg gaccgggccg gtggccaccg tgacccggcc gctgcgcacc
    20101 agcacccact cgccgtcgcc gccggccacc gtcagcgggg cgtccaccgg caaccccgcc
    20161 ttgaccaggc actccttggc gcaccagacc cgggtggtgg cgacgtcggc gtcctcgccg
    20221 aggtcggcgg cgatctgccc ggccagcccg gcgtgccggc cgagcaggtc ggcccacacc
    20281 tcggcgggcc ggggccggac cacctccagg tcgcaggcaa gcggcccggc gccggccacc
    20341 agcaggctgg cgacctcgct gtgggcggcg gagacgtgcc ggccgttgac ctcctcgggc
    20401 cgcccgtccg gccggtaccg cagccgcacc ggccgtccca cggcccgtcc gacggcgacg
    20461 gcggtgacct cccgtcgtgc tccgccggtc cggtccggac gcggttccac caccaccgcc
    20521 aggtcggcgt cgagcagccg gcccagccgc cgctccagcg ccggtccgag cagcgccggc
    20581 ggccacggca gggcggccgg gcggtggcgc accgcgcgca ggcgcagacc gagccagcgt
    20641 tccaccaccg tcccggccgc gccgaggacc gtcacgtcgt accggtaggt gtcgtcgcgg
    20701 tgctcccgct ccaccgccac gaagcggacc tgctcggtgg cggcgagctt cggcccggcc
    20761 ggctccaccc ggtccacggc gatcggcagc agcgtcgcgt ccggcacgca gacctggatg
    20821 ccgtgcagga aggcgtcccg cgcgcccgcg tcgccgagca gcagccgctg cggcaggaac
    20881 gcgtggaacc agcgcatgtc ctcggtggtg gcgacgtccg cttcggcccg ccgggacgcg
    20941 acccggtggt agcgcaccag ccggcggaac cggtcgccct ggaagagcag gtcaccgtag
    21001 aggtcccggc ccggctccag cggcaccggc ggcagcccgc cggtcacgcc cggcgcctcc
    21061 cggtcgccct cgtccggctc gaagcggacg gtgccccgga agtggtcggc cgcgaagccc
    21121 gtctcgtcgc tgcggatcgc cacctccacc acgcccgcct cggcctgcac cgcggcgatc
    21181 cggacggtga cgcgcccgcc gcgggccacc accacgggcc gggggaagct gacgccggtc
    21241 agcacgggca cgccggtggc gccggcgagc gcggtggcca cctgcgccat cgcctccatg
    21301 ccgagcaccg cgggcagcag gaggttgccg tccaggtcgt gctcggcgag gtacgggtcg
    21361 ctctcggccg acaggtccgc ctcgaccacc agctccacgc cgtcgtactg caccagcgga
    21421 cgttccagga agcgcagcag cggcagctcc cgccgctcgt ggcgcagcgt gtccagcccg
    21481 tcggtgcggc cggtgaccac caccgaggcg ggcagccggg gcagcgccag cacctggcgc
    21541 agcagccgga caccctcgtc cggcgggatg ggggtgatgc cggcgcgcag cagcgactcg
    21601 acggcggaga gccgttcacc catgccgacg ccggaccaga ccgaccattc cagacagacc
    21661 gcgcggcatc cggtgaagcg ccggccggcc tcggcggtca gccgggccag ccagtcgttg
    21721 gccagcgcgt agtgcgcctc cccgggcagg ccgccgcgcc cgatcacgct gccgaacgtc
    21781 accagcagcc gcagctcgtc cggctcgacc gcggtgagga catgcgccag gccgtccacc
    21841 ttcggcgcca gcgtggcgcg cagggtgtcc gggtccagcg cgccgagggc ggccggccgg
    21901 ttgaccccgg cgccgtgcag gaccccggcg accgggccca ggtgcgcgcg tacctgcgcc
    21961 accgcggcgc gtaccgcctc cgggtcggtg acgtcggcgc gcacgtaccg caggcgcacc
    22021 cccgcctccc gcatccgggt caggttcgcg gccagctccg ggtccgcggc cgggtcggcc
    22081 cggccgagca gggccagccg cgccccggtg tcccgggcca gggcgagcgc gcactcggcg
    22141 gtgatgccct tcccgccgcc ggtcaccagc aggacgtcgt ccggccgcag cggcggaccg
    22201 gccggacccg ggcgtgccgg gccgggcggc ggcagcggcc gcagcagggg gacccgccgc
    22261 cggccgtccg ggccgaggtg cgactcggcg tacccgtcgg tggccgccac ctcgcgcacc
    22321 acccggccca ccaggtcgtc ggccggggcc gcctcgacca gcgtcacgtg cagacccgag
    22381 ccctccagcc gggcggtacg ggccagcccg gcgacgcccc ggccgtgctg gacgaccacc
    22441 aggcgggcac ccggaggctg ggccaccgcc gcctggacgg cgcgcaacgc gaggtccagg
    22501 tccacctcct cgcccgggca gagcagcacg ccgccgccga cgcccgcacc ggcgagcgcg
    22561 tcgcgcagcg cctccgcgta cgggtgcccg gccggcgcgt accactgcca ggcacccggg
    22621 ccgccggggc cggcgccggc cggctccacc ggttcctcga ccagctcgac tgtgaaaccg
    22681 cgcacccacg gggcgacgcc gtccacccgc cggtcggcgg gcggggcggc cgggtccagt
    22741 tcccgcagcg cgtcggcgat ctcccgcagc gtggcggtgg cgaagttcgt cggcgcctgc
    22801 accgcgggca ggcccagttc ccgggcggcc tcgttcacca gctgtcccac ggcgatcgag
    22861 ctgaggtgca gaccgtcgag gagccgggtg tccgcgccga cgctctcggg cggcagctcc
    22921 gcgcgggacg cggccagccg gcgcagcacc gccagcgggt cggccgccgg tccgcctccg
    22981 gccggggccg tctcgtcgac ggtcaccggc ccgcccgcgg cctgcggggt ggccccggtc
    23041 ggggacgccg ccgccacggc cacggcgggc gcggcctcgc acgggttggc gaagaagcgc
    23101 cgccgcgcgg ccaggtcgag cggacggatc ggacggtcgc tgaccagcgc ggcgtggtcc
    23161 acgggcgcgc ccagcgtcca gagcgcgccg acagtgccga ggaacccggc gagcgtcggc
    23221 gcgtccgtgc cggtggcgaa caccggcacg tcgaccagct cccgggccat ccgcgcgagc
    23281 acctggccgg gaccgacctc gaccagcgcg tccacccgcc ggccggcctc ggtgaccgcc
    23341 gcggcgaagc gcaccggctc ggtgatctgc cggcgcagca gcgccgccag gtcggtgccg
    23401 gaggtcagct ccgcgccggt gactgtggag accaccggcc ggcgcggcgg ggtcaggcgg
    23461 accccttcca gccagtcgcc gaactcgcgg gcggccgacg ccatcagcgg ggagtggaac
    23521 gcgtgcgaga cggccaggtc cgcccagtgc acaccggcgt cggtggcccg ctcgcacacc
    23581 cgccggaccg cgtcggacgg gccggcgacc accgtctgcc gcggcccgtt gtagccggcc
    23641 accaccaccg gttcggcgcc gatcagccgg gcggtgacgg tgtcgtcggc ggcgatgccg
    23701 gccatcgtgc ccggttcccg gcagccggcc atgaccgcgc cgcgcgccgc ggcgatccgc
    23761 agcagcgcct ccgcgtcgac ggtgccggcc cagtgcagcg cggtgatctc gccgaggctg
    23821 tgcccgaccg ccacccgcgc ctcgacgccc agttcggtga gcacccgcag gccggccagg
    23881 gaacccgcgg cgatacgcgg ctgggccacc tcggtggcca ccgggtccgc gtcggccggc
    23941 agcgccgcca ggcggtgcac ctcgccggcg gccgggaaac gccgggccag cgcgcctccg
    24001 tcgacgccgc ggccggagcc ctggccgggg aagaggaacc cgagccgggc cgggcgcagc
    24061 gtgcgccgca acgccagccc gtcggcgaac agctcctcct cgccccggtc gagcgccgcc
    24121 aggacacgct cgaaccggtc caccgcctcg gcgggggagg cggcgaccac cgccagccgc
    24181 atcggccggc cgcgtacctc gccggccaga gcgccggcca ggtcggtcag ctcgccgtac
    24241 gacagccggg ccagcggatc cagcagcgcg gccacccgtt cccgcagcgc caccgggtcg
    24301 gccgcgtcga gcagcagcag ctcggcgtcc tgggtgtgcc gggccagccg cagctgctgc
    24361 cgccggacac gttccggcac ggcggacggg ccggcctcca gcaccaggtg ggtgttgatc
    24421 ccgccgaagc ccatcgcggt gaccccggcg cgcagcggcg ccccgtccgg ccacggctcg
    24481 gccaccggcg cggcgcgcag cgtacggtcc gcggcggtca gctccgcgcg gggacgggcg
    24541 cacccggcgg tgggcgggac gatggcgtgc cgcaacgcca tggtcgcctt gatcagcccg
    24601 gccaccccgg cggcggcctt ggtgtgcccg atgagcgcct tgatggagcc gatggcggcc
    24661 ggatcggtgg ccccggcgtc gcgccgggcg gcggagaggg cacgcagctc ggtggcgtcg
    24721 ccgacggcgg tgccggtgcc gtgcccctcg aagagcggga ccgtgccgat gccgaagccg
    24781 gcccgctggt acgcccggtc cagcgccagc cggtagccgt gcgcctcggg ccgggtcatc
    24841 ccgccgcgcc cgtcggagga gacaccccag ccggcgatcg tcgcgtgcac gacgcgcccc
    24901 tgcgccaccg cgtcgtcgtg acgcatcagc acgaccatgc cgcagccctc gcccggccag
    24961 aagccctgcg accgctcgtc gtacacccgc atctcgtcgc gggccagcgc gccggccttg
    25021 gcgaagccga ccatctcgaa cgggtcgatg gacaggtcca ccccgcccgc caccgccacg
    25081 tcgacctcgc cgtcggccag ggcgcgcgcg gcggtgacca cggacagcag gctggaggcg
    25141 caggcggcgt ccaccgtcca gccgccgcca ccgaggtcga agtggttgca gatccgcccg
    25201 gcgatggtgt tggagagacc accggcgagc gtgtcctcgt cgatcggcgg gaacgggctc
    25261 ttgtaccgct cctcggtcac cgccaggaac tccgcgatcc gccggtcggg ccacccctgc
    25321 tcctgcagcc cggcggccag cacccggcgc acgtacggcc agcgcagccg cagcacgttg
    25381 gcgcgggaga actcgccggt gagggtgttg ccgaccacca cggcggtacg gtcccggggc
    25441 agcccggcgc cgtccggcca gccggcgtcg gcgagcgcct cgccggccac gtccagcgcc
    25501 agccagtggg tgaggtcggt ggagcggtag gtgctgccgg cgatccggtg ccggatccgg
    25561 tcgaacgtgt acccctcgat gacggcggcg tgccggttgt agaaacggtc cggggtggcc
    25621 gggtcggcgt cccagtagtc ctccaggctc atccgctccg gcggcagccg gcggaacgcg
    25681 cggcgtccgc tgagggcgtt gcgccacagg tcggccaccg aatcggcttc cgggtagcgg
    25741 cagctcatgc cgacgaccgc gattctgctc atgtcgtcac tcctggggtt gtgcgattcg
    25801 cggatcaggc gggcacgggc cgcttgccgt tgtccgcgga gacgggaccg gcggtggccg
    25861 gtgtcccggg cgttgcgggc gagacgggtt ggtcctgctc gcggcgccgc tgctcgcggc
    25921 gcgaggcgtg cagcgaccag aggaaggtgc cgcggaccag gcagacgatc gcggtggcga
    25981 agaagagccc gtacgtcacc gaggcgccgg tcagcacgcc gtacaccagc gccacgccgc
    26041 caccgaacgc gaactgggcg gccggccggc tcggcgtggt gcccggatcg gtgatcatgt
    26101 agttggtgaa caggacgaac gcggtaccgg tcatggtggc cagcgcggcc acgatcgacg
    26161 tgtccagcac caggccccgg accaccgact gcaccacgaa gatcgacagc cagccggcga
    26221 tcagccacat ccggcgggtg agcttcgcgt tgagcatcgt gccgaggacg aggatcacgg
    26281 ccacgatcgc ccagtcggcg gggccggaga ggttctcggt gaagtggtac ggcggcgcga
    26341 tggaaaccca cgggaacagc agcagcacga tcgcgatgcc gaagttcgac gggttcatga
    26401 agtgccgcag ccgcccgttg accggcgccc gcagcagcca cttgccgctg atcgccacca
    26461 gcacgccgaa gagcatcacc agcacccggt cgttggtgta gagcagcatg ttcaccgcca
    26521 gcgcggtgat gtgcgcgggg aagaggaact cgaccaggtt gcgcacgccg ccggcgtacc
    26581 ggggggcgcg gccctcaccc cgggcgccca ctgcctccag cagcagctcg gcggcgtacg
    26641 cggtgagcac ggcgtacacc ggccagagcg cgggctgctc gaagccgagg accgtgtagc
    26701 cgaggatgtt gaggacggtg atcgagatcg cgaagcggcg cagcgctgtc actcgcgggt
    26761 cgcgtggctt cgtcatgaac tcgcctcctg tgcctgggtg ccgagggtga gcgcgtgccg
    26821 gccgggggcg agcgtcaccg tctgcgcgcg tggcgcgccg gtgcggtccc gccaggccag
    26881 gtcgacctgg accggcccgg tgacgtcgcc gaggccgatg tgcacctcga agctgcgccg
    26941 gccggagtgg ccgctgccgc cgtcgacccg gccgcgcagc acacgaccgt ccggggtgcg
    27001 gacggtgacg tccgcgccga tcaccgggga gccggtggcg gcgtcgccgg ccggcggccg
    27061 gttcagcttc agggacagct gcgatccggt gccggggctg tcgttgcggt agaacaccgg
    27121 cgcgtcccac tgccgggcca ccgccatgtc cagccggccg tcgccgtcgg cgtcgccgag
    27181 cgcgatgccc cgggtcggga tgggcaccgc caggccgagc tggccggcga tgtcggcgta
    27241 ggcgccgccg ggcatccggg cgtgcaggcg cagcggctgc ccgccggcga tgtcgtcgcc
    27301 ctgccggacc cgtggccacg ccgaggtgtg ctccagcagc gtgtcgttgg cggtggccag
    27361 ctcctgcagc tgcgcccacc ggttcacctc gcccttgacg aagccgctgg tctgcacgat
    27421 gtcgggccgg ccgctgttgg tcaggtcggc gatcttgacg tcccagctcc agccgctcca
    27481 ggcgaggttg agcggggcgc tgcggtcgac gaacggcgcc cgcccgtcgg cgagccgctg
    27541 ccgcaggtca tcggtgtccc gggcctggtt gacgaaggcg aagttgctct cctggatgcc
    27601 gaacgaggtg gtgatgttgc cgacgtacat gtcgtagagg ccgtcgccgt ccaggtcgcc
    27661 gacgtccacg cccatgccct tgaaggagtc gtgcccgagg atcttcgact tgggcacggt
    27721 gagccggctg ccctcgccct cgaccagggc cagccgcacc cggcccggcg tggagcggtt
    27781 gtgcagcagt cggtcggggc cgaagtcgtt cgccacgtac agctcgggca gcaggtcgcc
    27841 gtcgaggtcg gtggcggtcg acgcgagtgc ccagccacgg gagacgtcgt cgtcgaagag
    27901 gtccggcacg tcggcgaagg tgacgctgtc ggcggtcgcg ccggtccagc gcaggacatg
    27961 gtcgcgcccg ccgttgtacg cggccgacat ggacctgttc atcgccacgc cgccgctgac
    28021 cgtgtggtcg agcaccgggc cgtcggggaa gtagttgccg acgaacacgt cctcgtgacc
    28081 gtcgccgtcg aagtccgcca cgctcaccgt gttggtgttc caccgcggcc cggtgtagcc
    28141 gccgtcggcg gcggcgggcc gggggaccag ctcgaccggc tggaacgccg ccgcggacag
    28201 accggtggcg tccgggcggg ccaggaagat caccggtgtc cggccccacc agtagaccag
    28261 caggtcggtg cggccgtcct cgttgaagtc gccgggcgcg cagcccatcg gcgccatgtg
    28321 cggccccatc ggcagcggcg ccgggtcgag cacgaacggc tggtaccgct cctggcgcgc
    28381 cccgggcgtc ggcgtgacca ccacccggtc gatccgcggg tcggtgacgc agaggtcgtt
    28441 ggccaggccg tcgccgtcga tgtcgttcat ggcgaccccg gcgcccaccg acgagatcca
    28501 cgcgtcgatg tgcgtgtact ccttgttgac ccggcggatg ctttgctgcg gcaggccacc
    28561 cgggatcgcg atggacagcg gcgtgaaccg gtagcccgcg gccacccgtc gccgttcctc
    28621 gtcggtagca gtggccggct cggcgatcag gaacaggccg acgatcagca gcagggcggt
    28681 cagcccggcg agatgacgtc ggccccaacc caggatcatg gacacccggt cagcacctcc
    28741 ccagcagtac gagatggtcg gcgatccgct gacgccacac cgcgaaggcg ggcagcgacg
    28801 ccgagtcggt cagatcggtc agggcggcat cggtgatcgc ggcggcctgc tcgatgctgg
    28861 tgacgcagaa cgcgccgacc gcgacagcgg tgtgcgtcgg cacgtgtccg gcccgcatcc
    28921 gggccttggc cgcgaacgcg gcgccctggc cgagcgccgc ccggtgctcg ccggccgcct
    28981 cgcgcagcgt tcgcagttcc gtcagatcgg cgccaccggc gtagctggcg gccaggccga
    29041 ccccgctcca caggtcggag tgccggtcgg cggggaaccg gtggagcagc cggaccagtt
    29101 cggccgggtc ggcgccggcg acgaaccaca gcgcccggcc gatgccctgg tccaccgcgt
    29161 gcggcgcgta gtgccgcagc tccgccggcc agatgtgcgc cgggtcgcgg tgccgtgcgt
    29221 ggacgtaccg gccggtgtgg aagtaggcct ggtggaagcc gtagccgtcg agagcgagcc
    29281 agcgcagcag cgggtcgggc gggaggatgg ccggccggcg ccagcggggc agccgggcca
    29341 tggcccagcc ggcgcccacg tgggccatgt agacgtgcgc gtcgccgcgc ccggccagga
    29401 accgcgccat gccccggccg ccgccggggc ggaggccgtc catcagggcg tacgccatcg
    29461 cggcgccctc gtaggcgaag ccgcgcagcg gcgccggccg gctttccagc agttcctcgg
    29521 cggcccgggg ctccggcgcc ccggcggcgt caccgaaacc gccgatgaaa ctctgcccgg
    29581 cgctttccag ggcctgccgc gcggcgtcgt tcttgacatg gaagccgcgt gtgtcaaaca
    29641 acgcctcgcg cttatccggc gtcaggattc gttgtcgcag tgccaacaat attcgggcca
    29701 tggcaagtcc aattcgccgt gggtgtacgc gtgcggatcc tgctcgcctg cagagaagtt
    29761 cttcgattgg cgtgcccgct ctggccaata ctcgcggaac gcctcggcga ctgtcttctc
    29821 gcaggttgct gtgttgcctc aggtgaccgt cggcaccgct tcggcgggcg cgcgaagccg
    29881 ggtgcgcgca agcctggaag tgggtcccgc accggctccg gccagcacgt atcgcccgcc
    29941 gccgaggacg cccgagcggc ccgcgtgcgg caaatcaaga ctcgttcaag agccgcacag
    30001 cactattggt cacggtttcc gggtagcgat ggaggggcca tggggcagtt ttcaggtgcc
    30061 gactgcaagg aacatgacgg ccggtcggcc gccattgtcc gggtgattga gcacatgaaa
    30121 agagagctcg gcaggccgtt gccgctggaa acgctggcgc gccttgcccc gttcagcccc
    30181 ttctatttcc atcgcgtgtt caagcaggcc acctcgatga caccggcacg tttcctggcc
    30241 gccctgcgga tggccgaggc gcgacggctg ctgctgcgtt cctcgctcac cgtcacggcg
    30301 atcagcgccc aggtcgggta ctccagcgtc ggcacgttca ccacccagtt ccggcgctgg
    30361 gtgagtttgc ccccggagcg gttccgccag ctcgcccggc agttggcggg cgtgtcggtg
    30421 gcggcgctgc tgccggtgat ccgcagccgc gcgatagtcg ccggccaggg cccccgggcg
    30481 ctgatgcacc tcgacaccgt ggacctgccg gggctgctgc tcgccgcggt ggcgccccac
    30541 gacggggggc gcaacgaatg gtggacggcc gcgcctcgcc cgctgccggc cgcgctgccc
    30601 gccaccgtgc cgccgggcga gcaccgcgcc cgggtcctgc tgctgcgccc ggaccgggac
    30661 gccacctcgg cgctcgtcga cggcgcgccg gacagcttcc tgatcggcga cgcggacctg
    30721 cggataccgg ccgagacggg cagcgcccag cgcatcaccg tcgcgcgggc cacgctcacg
    30781 gtgccggtgc ggcaggtgcg ggtcaccgat ccgccgttgc tctccgccac gccgctgcgc
    30841 tggctgctgg gcgtgtcgca ggccggctgg cgggggcgga cgccggtgat ggccgagcgg
    30901 cgcgcgctcc gaaccgcctg atggccgtgc cggccccgaa gatcgagctg cacgtccact
    30961 tcgaagggac ggtgcggccg gagacgctcc tggtcatcgc ccgccgcaac ggtcagcggc
    31021 tgcccgcgga gacggtcgag ggtctgcgtc agctctacga gttcaccgac ttcgaccact
    31081 tcgtccgcac ctgggtgttg accaccaact gcctgcgtac ggccgacgac ttccggcgca
    31141 tcgtggtggc gtacgccgcc gaggcggcca cgcacggcgc tgtctacctg gagggcatct
    31201 tctcgccggc cgagcgggtg cgccggggcg tcggctgggc ggacatcttc gaggggtacg
    31261 ccgacggcgc ggccgaggcg tacgagcggc acggcgtacg ggtgctgttg acgcccgacg
    31321 tggaccgcga gctggcgccg gccgacgccg aggagtgcgc ccgccaggcc gtgcggtacc
    31381 gggaccgggg cgtggtcggg ttcggtctgg gcgggccgga gctggccgcg ccggcgaagg
    31441 cgttcgcccg ggcggtggcg atcgcccgcg acggcggtct ggcgttcgtc ccgcacggcg
    31501 gcgaggcggg cgggccggat tcggtacgcg acctgctgga gctggctccg gcccggatcc
    31561 gtcacggcat ccgggccgcc gaggacgacg acctgctcgc cgagctgcgg gaccggggtg
    31621 tggtgctgga cgtgtgcccc acgtcgaacc tgcggacccg ggtggtggag tccgaggccg
    31681 cgcatccgtt gccccgcctc gtcgccgccg gtctgcgctg ctcggtcggg accgacgacc
    31741 cggcgatgtt cggtaccgat ctgggccgtg agcacgagtt ggcggcgcgt ctcgggctcg
    31801 ggcccgagcg ggcgtacgcc gccggggtgg ccggggcgct ctgcgacgac gcgacgcgtg
    31861 atcatctgat ggcggtgggc cggcgggcct acggctgacc cgtcggcacc ggcttgccgg
    31921 cccggaagac gagtgtggac gtgtcggtgt cgtcggggtc gccttcgcag tccacgacca
    31981 cgatctgacc ggggggcagt tcgttgaaca ggatccgttc ggacaggttg tcttcgatgt
    32041 cgcgttggat cgtgcggcgc agtggccgcg cgccgaggac ggggtcgaag cccttcttcg
    32101 cgaggtactt cttggcgttg tcggtcagct ccagacccat gtccttgttc cgcagctggg
    32161 tctcgatccg ggcgatcatg atgtcgacga tcgacaggat ctcgttctga cgcagctggt
    32221 ggaagacgat ggtgtcgtcg atccggttga ggaactcggg ccggaagtgc tgcttgagct
    32281 cgtcgttgac cttctgcttc atccggtcgt agttcgactc ggagtcctca gaggcctgga
    32341 agcccagcga caccgccttg gcgacgtcgc gcgtaccgag gttggtggtc aggatgatga
    32401 ccgtgttctt gaagtccacg atccggccct gaccgtcggt gagacgcccg tcctccagga
    32461 tctgcaggag cgtgttgaac acgtccgggt gggccttctc gatctcgtcg aagaggacca
    32521 cggagaacgg ccggcgacgc accttctcgg tcagctgccc accctcgtcg tagccgacgt
    32581 agccgggagg ggcaccgacg agccgggaca cggtgtaccg gtcgtggaac tccgacatgt
    32641 ccagctggat cagcgcgtcc tcggacccga acaggaactc cgccagggcc ttggacagct
    32701 cggtcttacc gacgccggac gggccggcga agatgaacga gccggacggg cgcttcgggt
    32761 ccttcaaccc ggcccgggta cggcggatcg ccttcgagac cgccttgacc gcgtcttcct
    32821 ggccgatgac gcgcttgtgc agctcgtctt ccatgcgcag cagccgggag gtttcctcct
    32881 cggtcagctt gtagaccggg atgccggtcc agttgccgag gacctcggcg atctgctcgt
    32941 cgtcgacctc gctgacgacg tccaggtcac cggccttcca ctccttctcc cgctgcgcct
    33001 tctgcccgag cagctgcttc tcggtgtccc gcagctgcgc ggcccgctcg aagtcctgcg
    33061 cgtcgatcgc ggactccttg tcgcggcgca cctgcgcgat gcgctcgtcg aagtcgcgca
    33121 ggtccggcgg cgcggtcatc cgacggatcc gcatccgggc gccggcctcg tcgatcaggt
    33181 cgatcgcctt gtccggcagg aaccggtcgg agatgtaccg gtcggcgagc gtcgcggcgg
    33241 cgaccagggc ggcgtcggtg atggagacgc ggtggtgcgc ctcgtagcgg tcccgcaggc
    33301 ccttcaaaat ctcgatggtg tgggccagcg acggctcacc cacctggatc ggctggaaac
    33361 gacgctccag agcggcgtcc ttctccaggt gcttgcggta ctcatccagc gtggtggcgc
    33421 cgatggtctg cagctcaccc cgggccagca tcggcttgag gatgctggcg gcgtcgatcg
    33481 cgccctcggc cgcgcccgca ccgacgagcg tgtggatctc gtcgatgaac aggatgatgt
    33541 caccgcgggt gcggatctcc ttgagcacct tcttcagacg ctcctcaaag tcaccgcggt
    33601 agcgcgaacc ggccaccagc gcgccgaggt cgagcgtgta gagctgcttg tccttcagcg
    33661 tctccggcac ctcacccttg atgatcttct gggacaggcc ctccaccacg gcggtcttgc
    33721 cgacgccggg ctcaccgatc agcaccgggt tgttcttcgt gcggcgggac agcacctgca
    33781 tgacccgctc gatctccttc tcccgcccga tcaccgggtc gagcttgccc tcccgggcgg
    33841 cctgggtcag gttccggccg aactggtcca gcaccaggct ggtcgacggc gcggcctcac
    33901 ccggcgcggc accggcggcg gccggctcct tgccctggta gccggagagc agctggatga
    33961 cctgctgacg cacccggttc aggtccgcgc ccagcttcac caggacctgc gcggcgacgc
    34021 cctcaccctc gcggatcagg cccaacagga tgtgctcggt gccgatgtag ttgtggccca
    34081 gctgcaacgc ctcacgcagc gacagctcca gcaccttctt cgcccgcggc gtgaacggaa
    34141 tgtgcccgct cggcgcctgc tgaccctggc cgatgatctc ctcgacctgc tgacgcacac
    34201 cctccaggga gatgcccaga ctctccagag ccttcgccgc gacaccctca ccctcatgga
    34261 tcaggcccaa caggatgtgc tccgtaccga tgtagttgtg gttgagcatc cgggcctctt
    34321 cctgggccag gacgacaacc cgtcgcgctc ggtcggtgaa ccgctcgaac atgccctcgt
    34381 gctcctcacc tgagtcatcc ggccaccaga atactaagat ttcatatagc attctgtcta
    34441 tcctggatgc gcgacacggg cctccaggtg ggcggcatcc ctttcagggt gggccttcgt
    34501 cggaaccggg tcacgcaacc cggcacggcc cgcaacttct atcaatagct tcgccatatg
    34561 aaaaagaact ccccgccgtc gtcgttccgc ccggcggcct ttacgcacgt cccgggcggt
    34621 gatcacgctg ctcgggcggg ttggcggcct ggcctgccga gtttcctgag caatagctga
    34681 gtgtggcgac gtggtaaccg gatgtgccag tctcgggctc acgctgagcc tggggggata
    34741 gatgatggag agtcgcgcct gttaccgggt cgacctgttg ggtccgctgc gcgtgcggcg
    34801 gaaggggcat ccggtggagc ccggaccggc caagcagcgg gcggtgctct cgcttctggc
    34861 gttacgcctg ggcgacagcg tcccggtgag cgaggtggag gaggcggtct ggggcggcgt
    34921 agtcccgccg agcgcccggt cgctcgtgca cacgtacgtg gcccggctgc gccaggtcct
    34981 cgaaccggag catccgccgc ggcgccgggt acgggtcatc gcctcgaccg tcaccgggta
    35041 ctcgctgcgc gccgagaccg tcgagacgga cgtcgcgcgg ttccgccgct gtgtcgccga
    35101 ggccgagaag cggatcggcg agggctgccg tgaggaggcg ttccacctgc tcgggcaggc
    35161 gctggacctg tggcgcagcc cgaccctcgg tgagctgcgt tcgctgctgc acgacaacat
    35221 cgaggtggag gccctgggtg cggcctgggt ggcgacctcg cacagctacg tcggtctggg
    35281 gctgcggctg ggacgcgccg cggcggtgct cgacaccgcc acccggctgg cccggctgga
    35341 acccctgcac gaggcgatcc aggccgacta tctggccgtg ctcggcagca gcgggcaccg
    35401 gaccgtggcc ctgcaccggt acgccgacat caccgagcgg ctccgtaccg aactgggcgt
    35461 cgacccgggg gaggaactgc gggcggtgca ccgggcgctg gtgcgcccgg ccggccgtcc
    35521 accggtgccc cggccggcgc cggcggtgcc ggccgcaagg cgcaggcccg gctgcgggcc
    35581 gatctccggg ccgctgcact ggcgggccgg ggacatcgcc gacctggcgg ccctgctggc
    35641 gaagtaccgc gcggtgaccg tcaccggcgc gcccggctgt ggcaagtcgg cggtgaccct
    35701 gcgcgccgcc caccaggccg cccgtgtctt caccggcggg gtcctgacgg tggacacgct
    35761 cgatctcagt gaccggcggc agctggaacg ccggctggcc cggatgctcg ggggcaacgg
    35821 cgccgaggat ccggtcgaac tgctgcgcga ccagccgaca ctcgtggtgc tggacaacgc
    35881 cgagcacctg gtcgacgcgt gtgcggtggt cgccgaccgg ctgttgctgg cgtgcccgga
    35941 cgtggcggtg ctgaccggct cgcgtcagcc gctcgggctg ccgtacgagc gggtccagcg
    36001 cctgcatccg ctcccggtgc cgcagccggg cggatggccg tcggtcctgt ccaatccggc
    36061 ggtcgcgctg ctcgccgaac gggcggccca ggcccgcccc gggttccgcc tcgaccggcg
    36121 ggacgcggag gtcgcggtgg agatctgccg ccggctcgac ggcctgccgc tggccctgga
    36181 gatggcggcg gcgtgcctgg ccaccgagag tctggacggg gtgctgcgca agctggaggg
    36241 accgctggac ggactgcgcc cgcccgccgc cggaccggag tcacgccaca cgtcgctgcg
    36301 ggcgatgctc gaccgtagcg tccagcgcct cgacgtggcc gagcgttgtc tgttccagcg
    36361 cgtcgcgttg ctgccggggg tgttcgacct ggcggccgcc cagcggttct ggcggcccca
    36421 tccgtccggg cccacggacg tgcgggtggt gctcgccgcc ctggtggaca agtccctggt
    36481 gatgccggtc gggacgaccg gcggccggta ccggatgctc ggcctgctgc gccggctggc
    36541 gctggagacg ggtaccccgg gggccgtgac gagtcccgcc gccgaactgc ccctgccgct
    36601 gccccggccg ttgctgccgg ccggcgcggc ggccgtgccg gactgaccgg cggccgccgc
    36661 gacggcccgc tccccgccgg gggagcgggc cgtcgcgttc tggaggccga tgacacctga
    36721 cgatgcccca ggcattgaca gcacgcttta aaaacacata gcttgaagtt cggcgggacc
    36781 ggtcgggtcc ggtccaccag cggccctcag accgccgctg acccctgccg acagacattg
    36841 gaggtgtctg gcttgagcac cagagagacc tacgagtccc tgaacctcga acccaagccg
    36901 atccgcccgc acatcctcgc cgcggcaacc gtggtcttcg gcgaggacta ctactcgggc
    36961 cgccgcgaga cgatcaacct gtccggcttc gtgcagctca acaagtggcc catgccgggc
    37021 ttcgagcaca aggtcgacga gaacggctac gcgcagttcg ccaccgagct gatcagcgcg
    37081 cccgaggtgg gcatcaaggg gttcagctac gagttggacg accgcatcca ggtcctgtcc
    37141 aacccgttcc tgcccaacag cgggcacgtg cggcagatcg tgccgggcaa gaacttcccg
    37201 gccgagttct acatccgccg cttcggcatc ctggagtcga gcacgctgcg gctcgcccac
    37261 cgcaacgtca tcgacatcta cggcgtggtc gacagcgtcc cgccgttcaa gaagccgctg
    37321 accgggccct acctgggcaa gccgcgcggt gacggtccct tcgacgtgat ggccgcgccg
    37381 aacgtcgtca agggcaccac gctgccggag gcgtggtacc cggccaacga cgagaaccag
    37441 ccggtcggga tcacgccgaa cctgttcttc gcgcccagcg ccggcccgtg catgtccatg
    37501 ctggtcgacc cgtccatgat catgcagacc tcgctggagg ggcagatcga ggtcgaggtc
    37561 aacggcaaga cggtgcgggt cgacctggcc ggggactacc gcaaggcggc cggtgccgag
    37621 gtgctgctct tcggcccgga caagcacgac gagggcccgg gcgtgctcgc ccagctggcc
    37681 cgcgtcgcgg tcgtcggaca cagcccggag ctgggtggcc gggtcatgct gcgggcgagc
    37741 tggccgcggg tctccggcgg cacgctgggc gagggcaacg aggacagcct cagccggctc
    37801 aagttccccg gcgacctgca catcgacgcc gagttcgagc tggtcacgcc gcacgagacg
    37861 ctctacgccg ccaactccgt gcacgtcaac ggcaagatgc gcggcatgga ggccaccggc
    37921 accgagctca agctggacgg ctcggacacc gccctggtca ccgtggacga gcagccgaag
    37981 gctcgcctca ccggcgtcaa cctggtgatg cgggacgcgc tggtcggcga gcacgccgcg
    38041 gtgaacgcct gaccgacggg tccgcttgac gggcctgccg ggcagaggtt ctactagtaa
    38101 aaccaatagc aacgtaccgt cacgatgtcc ctcccggctg ctacggcggt cgggagggac
    38161 gcgcgctcag ggggtaccgc gtggaccagc ggctgctgct catgcaccag atgatgctcg
    38221 gcgacgcgcc ccggctgcgg gcgtacgaca gggcgctgga ggaggccgtc acccccggcg
    38281 acgtggtggt cgacgtgggc gcggggctgc tcgcgctctc cctgctggcg ctgcggcacg
    38341 gcgccgagca cgtgtacgcg gtcgaggccg acccggccac cgccgcggcg gcggcccgca
    38401 tcatcgaggc caacgacctc aagggacggc tcaccctggt caccggcgac gcccgtacgg
    38461 tccggctgcc ccgcaaggcg gacgtgctgg tctccgagat gatgggaaac ctcggcccgg
    38521 aggaggagat ggccgaggtg ctgcacgtga tcgcccgtcg ccacctgcgc cccggcggcc
    38581 gggtggtgcc ccggcggctg cggacctggc tggccgcggc cgagttcgcc gacgagggct
    38641 gggggctgtg gggcggcgac ttctacggct accggctcga cccggtgcag gagctcgtgg
    38701 ccccggcggc ccagctgcac ttcttccagc gtccgccgaa gctgctgacc gagcccacag
    38761 tggtgctcga ccaggcgctc gacggccggt cgccgtcccg gcagacgctg cggcagcggc
    38821 tgccggtcat cgcgccgggg aggctgcacg ccgtgctcgg cttcttcacc gccgacttca
    38881 ccgacgacgt gacgctgtcg aacttcccgt cgtaccccgg atgcaactgg gcggtctggg
    38941 tgtggccgct gcggcacacc gacgtggccg agggcgacga gctgtccgtc gccctgcgcc
    39001 ggccggcccg gcgcgacgtc cgcgccgtga ccggctggcg gctggagtgc ggcctgtccc
    39061 ggcagaggag gtcctgatgc ccttcgcggt gggtaccgtc cgcgacattc ccgtccgtgg
    39121 cgctctcaag ctctgcggcc tgacctggtc cgcggagtgc ctctggttct ccgaggcggt
    39181 ctccagccag atcgcctccc tggacccgat cagcggcaag gtggtccgcc ggctcgactg
    39241 ccccggcgtg cgcaccgacc tgaccacgat cggcgggcgg ctgctgcagg tggcgggcga
    39301 cgaccgcgtg ctgcggctgg tcgatcccga ggacggcgag ctgctcggcg agttcggcaa
    39361 cccgcgtccc ggcaacgtgc tgtgcgggct ggaggcgacc cggcacgggc tctggctggg
    39421 ctacgaggac ctgcgccagg tcgacctgcg cgacccggac ggtttcgggc tgatcgacac
    39481 gttcccggtc cgccagccga tcgccggcct gaccgtctcg gacagctacc tcgtctactc
    39541 cgaccgcgac gcggccacca tcaacctgta cgacgtggcg gcccgccggg aggtggccgc
    39601 ctactcggtc gcgggcaacc cgaccggcat cacctgggac ggccgccgca tctggtactg
    39661 cgacttcacc accctgcagc tccgggcgat cgaggtgccg ggcatcacga agggttgacg
    39721 tccatggcga ccacgcgcgc tctgctggcc cgctcgaccc ggatcggcgc ggtcggcgcc
    39781 gcccacctgc tgccggtgct gccggcggcg ctggtcaagg cggtccgagg tgaccgggcg
    39841 gcggcccgcc ggctgctgta ccgccgtctc accacgttgc tgatgcggct cggcccgacg
    39901 ttcgtcaagg ccgggcaggt gctcggcacc cggcgcgacg tgctgccggc cgcgctctgc
    39961 gacgagctgt cggtgctcca ggaccgggtc gacccgatga cccccgagca gaccagccgg
    40021 gcgctggccg aggcgtacgg cagcgagacg cccgcggagt tcgcggagat cgacccgacg
    40081 ccggtggcca gcggcagcgt ggcctgcgtc taccgcggcc ggatgcccga cggcgccgag
    40141 gtggcgctca agctgcgccg tcccggcatc gagtcgacga tggccctcga cctcgcgctg
    40201 atgcggcacg gcgcccgggt gatggcccgg ctgccgatgc tgcgcggcgt cccggtgcgg
    40261 gaggtggtcg agaacatgtg cggcgcggtg ttcggccagc tcgacttcgc ccgggaggcg
    40321 gagaacctgc gccggctcaa ggagaacctc gccgtggtgc cccgggtccg ggtgcccggc
    40381 gtacgcgacg acgcctgccg gccgcgctgc ctggtcatgg agttcatgcc ggacctcgac
    40441 gtggacgtgg cgcggtcgat gtcggcggcc gtgcgaaagc ggttcgccgc ctctgcgatg
    40501 acagcgatct accacatgct cttcgtggac ggattcgtcc actgcgacat gcacccgggc
    40561 aacctctact tcacccgggg cgcccaggtg gtggtgctcg acgccgggtt cagcgtgcag
    40621 ctcaccgagg agctgcgccg gctgttcgcg gagttcttca tgaacatgtc gatcgggcgc
    40681 ggccggtact gcgccgagat cgtggtgcgc agcggcaccg gcctgcggcc ggacgccgac
    40741 gtggagacgt tcctggtccg gatggccgac ctggtggagc gcagccacgg gctgccggcc
    40801 cgggagttca gcctgatcgc gttcgccgcg gagatgttcg acctgcaacg ccgctacggc
    40861 gtgcacgccg cgccggaact catcttcccg ctgctgtcgc tgctggtgat cgaggggacg
    40921 gtacgcgagc tcgaccccga cctcgacttc caggagctgg ccaagccggt gctgatgcgg
    40981 gggctcttcg gccgccgggc cgccgcctga ccgctggccg aacggtccgc cgggcctggc
    41041 cggtcgcttc gacagcgcgt ccccacctgc gcaaacagcc gactaaaata tacgatagcg
    41101 gaatggcaca gactggcctc gccggcaagc gctcctacca ccagtactgc gggctcgcgt
    41161 ccgcgctcga cgtgctgggc gaacgctgga cgctgctgat catcagggag ctgctgatgg
    41221 gtccccggcg ctacagcgaa ctgctcgcgg acctgcccgg catcggcacg aacctgctcg
    41281 ccgaccggct caagttcctc gtcgactcgg gcgtgctgcg gcaggtcgac gtgcacggca
    41341 ccggcggccg gctctcctac gagctgaccc cgaccgggca ggcgctgcgg ccgatggtgc
    41401 tcgggctcgc gcactggggc ctggagttcg tcggtgacct gaacgccgag gacacggtcc
    41461 gcccgcactg gggcttcctc gccgtggagg cgatgttcca gtgggacaag atctccccga
    41521 tcgacgagag ctaccagttc caggtcgacg acgaggtctt ccgcatcgac gtcgccggcg
    41581 gggtgccgcg cgtggcgaag gggccgtccg acgacccggc gatggtggcg accaccgacg
    41641 cggccacgtt cgtgcgcatc ggcgccgggc gggtcacgcc gctgatggcg atggtcggcg
    41701 ggcagctcaa gctggagggc gacatcgacg cggtgctgcg ctgctgcgag ctgctcggcc
    41761 tggacgccgg cgccgcgccc gccgctcaga cgacctccgg tcactgaccc gcgccagggg
    41821 gtgacgggac cggatcacta tattattctg aactagcctc ggcgttcgtc ggggcccgtc
    41881 gtcgtccggc acgccgcgcc cgtgcggcac ctcccgagca ctgtggtccc acggggacga
    41941 ccggtccgcc ctccgtcgcc cgagcgcctg acggcgtccg tgcgcgtcgc gggggcgacc
    42001 ccgcgcggcg cgtacgccgg caccgacgac cggccgtcaa gcgacaggag ccggcatgac
    42061 ggacacggtg cgacacgatc cggaggcgct gcccagggcg gtacgggacg acttccccct
    42121 gctggcccgc cgggccggcg acctcgtcgc ctacctggac aacgccgcca ccacgcagaa
    42181 gccccgcgtc gtcctggacg cgatcaccga ctactacacc ggggcgaaca gcaacgtcgg
    42241 gcgcggctac caccggctcg gcctggagtc caccgagcgg tacgagcagg cccgcgagag
    42301 cgtcgcgcgg gcgatcggcg cggcgcagcc ggaggaggtg ctcttcaccg ccggcaccac
    42361 cgccgcggtc aacctggtcg cggacaccgc cgggcaacgg gtggccgggc cgggccggcg
    42421 ggtcgtggtg accggcatgg agcacaacag caacctgctg ccgtggcgcc ggctctgcga
    42481 ccgtacgggc gccacgctca cagtggtgcc ggccggaccg gacgggcggg tcggagccga
    42541 ccggttcgcc gccgcgctcg gcccggacac cgcgctggtg gcggtcaccc acgtctcgaa
    42601 cgtgctcggc accgtcaacc cggtacggga gatgaccgcc gccgcccgcc gggtcggcgc
    42661 gctggtggtg gtcgacggcg cccaggccgt accgcaccgg ccggtcgacg tgcgcgacct
    42721 cgatgccgac ttctactgct tctccgggca caaggcgtac gggccgatgg gcgtcggcgt
    42781 gctgcacggc cgccgggacc tgctcgccgg gctgcccccg taccaggtgg gcggcggcac
    42841 cgtgaagggc gtcgcggccg accagccggt ccgctacctc gacgggccgg cccggtggga
    42901 ggccggcacg ccgtacgtgg ccggcgcggt cgggctggcc gccgccctgg actacctgcg
    42961 cgacctcggc tgggacgcga tccgccggca cgaccgggcg ctggtccggc acgccgtcga
    43021 cgtgctcgcc gcgatcgacc gggtgcgggt ggtcggtgac ccggccgccg accccagcgg
    43081 catcgtctcg ttcgtggtcg acggcatcca cccgtacgac gtcggggcgc acctggaccg
    43141 gcacggcgtg gcggtgcgct gcggcgtgca ctgcgccagc accttcctcg acgagatggg
    43201 cctgctcggc acggtccggc tctccttcgg cgtctacaac accaccgccg agatcgacct
    43261 cgtcggcgag ctgctcgccg gcgtacgacc gggtccctgg accaccgacc accccgacgt
    43321 ccggttcctc tgagcagcgc ccggaaggga gcgtcatgag gttcgacacc cggctggtgc
    43381 acgtcggcca gcgaccagtg cccggcaccg gcgacgtggt gccgccgatc cacctcgcca
    43441 ccacctacga ccgcaccgcc caggacccgc cgcgctactt ctacgcccgg ggcgagcagc
    43501 ccaaccggga ggcgctggag gagtgcctcg ccgcgctgga ggacgcccgg cacgcgaccg
    43561 tctacaccag cgggcaggcc gccgccacga cggcgctgtc gctggtgccg ccgggccggc
    43621 tggtgctcgc ctccgacgac gtgtacggcg gcacccacca gttgctcgcc gccgccgccg
    43681 agcgcggcgt gacggtccgg ccggtggatt tcgccgaccc ggccgagcgg gaccgcgcgc
    43741 tgtccgagtg cggtcccgag ctggccatgg tgtggctgga gacgcccacc aacccgctgc
    43801 tcaaggtcgc cgacatcgcc gcggtgtccg acctcgcgca ccggcacggc gccctggtgg
    43861 tggtggacaa cacgctggcc gggccggtac tgcaacgacc gctcgcgcac ggcgcggaca
    43921 tcacgctcta cagcaccacc aagtccgtcg ccggtcatct cgacgtgctc ggcggcgcgc
    43981 tcgtctacca ggacgaggag ctgcaccggc ggttcctggc ctaccgcacg gtggccggca
    44041 acgcccccgg cggcttcgac tgctacctca cccaccgcgg tctgaagacg ctgtccctgc
    44101 gcaccgcccg gcaggtggag aacacccgcg cggtggtggc ggctctgctg gccgagccga
    44161 gcgtcgcgac ggtcagctat ccgggcctgc ccacgcatcc gcagcacgcg gtggcggccc
    44221 ggcagatgac cgcgcccggc gcgctcgccg ccttcgagta ccgcggcgac ccggccaagc
    44281 tgctcgaccg ggtacgcctg ttcaccgccg cggtcagcct cggcggcgtc cgctccctga
    44341 tcgagtgccc ggcgctgatg acccaccgcc cggtgccgcc cgaggtacgc cggcgtctcg
    44401 ggttgaccga ccggctgatc cggatctcac ccggcatcga ggacccggcc gacctggtcg
    44461 aggacctggt caccgcgctg cgtgacggcg cctgacccgc tgaccggcat taccgccccg
    44521 cgaaggagga gacatgtccg cattcacgac cggcggcgcc ccggtggtgc tcgacggagg
    44581 actcgccacc gagttgcagc gcgccgggct gccgtaccag cccccgtggt ggggcaccgc
    44641 ggcgttgctg gcggacagcc ggcggcgcgt gctgcgcgac gtccacgagc ggttcctgac
    44701 cgccggggcg caggtgctca cggcgaacac gctgcgctgc aacctgcggg cgctgcgccg
    44761 cgccggactg gaggacgccg gcctcggctg gatggtgcac gcggccgtcg gcgtcgcgct
    44821 cgccgcccgc aacacggccg gcgcgcccgg cacccggatc gccgcgtcga tggctccggt
    44881 ggaggactgc taccggccgg acctggtgcc ggccgacgac gagctgcgtg aggagcaccg
    44941 ctggctggcc gtggagctgg tccgggccgg ggtggagctg gtgctggtgg agaccatgaa
    45001 caccgcccgc gaggcacgca tcgcggtgga gcaggtacgc gaggtgggcg cccgggcctg
    45061 ggccgccttc gtctgcgacg accagggccg gctgctgtcc ggcgactccc tggtggacgc
    45121 cgcccgcgcg gtgcgcgccg ccggggccga ggtggtgctt gtcaactgca ccgccccgga
    45181 ggcgaccgag cggtgcctgc gggcgctgcg cgacgccgac gacggcccga tcggcgcgta
    45241 cccgaacctg gaggaccgcc gcgacggcgc gcccgggccg cgcccgctgc tcgaccccgc
    45301 cgagttcggc gacctggtcg ccggctgggc ggtggagtac cggctcgccg tggccggcgg
    45361 gtgctgcggc gcgtcgccgg cgcacatcgc cgcgctgacg gcccggctga acgccccggt
    45421 ggcggccgtc gactgacgcc gcccgcaggt ccgccggccc ggcgcgggcc gggtcagcca
    45481 acgaagggag aacgagacgg tgagcggctc gacgatcgca ccgcccgtcg aggtggtgcg
    45541 cagcctgccc ggcccggccg gctacatgtg cggcctgacc tgggacggca cctggctctg
    45601 gcactccgac caggacgccg cgcggatctt cgcgatcgac ccggcggacg gcgcggtacg
    45661 ccggtccttc gcgtacccgg acgtgcgggc cgacctggga tacgcggacg gaaaactgtg
    45721 ccagatcggc ggccggccga agcggatcct gctgatcgac ccggccaccg gc
//
