LOCUS       NZ_KV411304            25422 bp    DNA     linear   CON 12-FEB-2024
DEFINITION  Nocardia terpenica strain IFM 0406 scaffold2, whole genome shotgun
            sequence.
ACCESSION   NZ_KV411304
VERSION     NZ_KV411304.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardia terpenica
  ORGANISM  Nocardia terpenica
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 4638951)
  AUTHORS   Buchmann,A., Eitel,M., Koch,P., Schwarz,P.N., Stegmann,E.,
            Wohlleben,W., Wolanski,M., Krawiec,M., Zakrzewska-Czerwinska,J.,
            Mendez,C., Botas,A., Moris,F., Cortes,J. and Gross,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-APR-2016) Pharmaceutical Biology, University of
            Tuebingen, Auf der Morgenstelle 8, Tuebingen 72076, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 30-JUL-2014
            Assembly Method                   :: CLC NGS Cell v. 7.0.4
            Genome Coverage                   :: 118.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/12/2024 01:56:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,832
            CDSs (total)                      :: 8,760
            Genes (coding)                    :: 8,562
            CDSs (with protein)               :: 8,562
            Genes (RNA)                       :: 72
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 40 of 198
            Pseudo Genes (incomplete)         :: 174 of 198
            Pseudo Genes (internal stop)      :: 9 of 198
            Pseudo Genes (multiple problems)  :: 23 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:51:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3062415
            Orig. end                         :: 3087837
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KV411304.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25422
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="21"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..25422
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25422
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:15422](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15422
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    38..53
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.27"
                     /tool="antismash"
     gene            complement(996..1427)
                     /gene="mraZ"
                     /locus_tag="AWN90_RS34930"
                     /old_locus_tag="AWN90_34955"
     CDS             complement(996..1427)
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0051302 - regulation of cell division
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mraZ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011208288.1"
                     /locus_tag="AWN90_RS34930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_34955"
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="WP_067591756.1"
                     /transl_table=11
                     /translation="MFLGTYTPRLDDKGRLTLPAKFRDELAGGLMVTKGQDHSLAVYPK
                     EEFAALARRAAAASRSNPQARAFVRALAASTDEQRPDAQGRITLSIEHRRYASLSKDCV
                     VIGSVDFLEIWDKQAWESYLAEHEEDYSLARDESLGGIF"
     misc_feature    1826..1844
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.93"
                     /tool="antismash"
     gene            complement(1875..2303)
                     /locus_tag="AWN90_RS34935"
                     /old_locus_tag="AWN90_34960"
     CDS             complement(1875..2303)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005247640.1"
                     /locus_tag="AWN90_RS34935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_34960"
                     /product="DUF3040 domain-containing protein"
                     /protein_id="WP_067591759.1"
                     /transl_table=11
                     /translation="MPLSEHEQRMLEQIESALYAEDPKFASSVRGGRLRSATGRRRLQA
                     AALFVLGLVLLIAGIALPVKPGGFPVISLLGFIVMFAAGVLLLLGGRGALGSGHRGGES
                     PSGPAGPVGGGKSKPRKSGGGFSARMEDRFRRRFEEGG"
     gene            complement(2430..2870)
                     /locus_tag="AWN90_RS34940"
                     /old_locus_tag="AWN90_34965"
     CDS             complement(2430..2870)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019928290.1"
                     /locus_tag="AWN90_RS34940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_34965"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_228786520.1"
                     /transl_table=11
                     /translation="MAGRMQHPGRSGRAGGLLDRADALLLQAGAEADPRERFRTAYLAA
                     LRGAGAVLALSGADRAPRARSRNAWVLMQQAAPEFVMWTDYFSSYSETRAALEAGLDRP
                     VDARRADEFASRVGAFLHDVEDLLATEARLRPITGWLADGTA"
     misc_feature    complement(2932..2947)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 24.46"
                     /tool="antismash"
     misc_feature    2955..2970
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.44"
                     /tool="antismash"
     gene            3064..3699
                     /locus_tag="AWN90_RS34945"
                     /old_locus_tag="AWN90_34970"
     CDS             3064..3699
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019928291.1"
                     /locus_tag="AWN90_RS34945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_34970"
                     /product="N-acetyltransferase"
                     /protein_id="WP_067591765.1"
                     /transl_table=11
                     /translation="MTALRPHHPHHSPAPVVVDLSAATLRARLHDALSVYVAAMDYPRG
                     TEHHRAPMWTEHTTRPGWQAVGAVLPDDSGEFDLRTAPLVAIAYGYHGAPHQWWHQQVH
                     SGMRRSGWPEYAARDLLSDYFELTELHVHPTAQGRGIGETLLMRLLRNRTERAALLSTP
                     EVDRENNRAWRLYRRQGFTDVVRHFVFSGDTRRFAVLGRRLPLEAPSR"
     gene            3696..>5183
                     /locus_tag="AWN90_RS34950"
                     /old_locus_tag="AWN90_34975"
                     /pseudo=""
     CDS             3696..>5183
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014350112.1"
                     /locus_tag="AWN90_RS34950"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_34975"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTVLIVGSGHNALVAACYLARAGQAVEVLERDEVLGGAVSTVPRF
                     PGHLVDRGSSAHIMIRHTGIVEELELDRFGLRYIDCDPWGFAPAPAGTERPPLVFHRDL
                     DRTCASIAAACGAREAEAYRRFVRVWGPRSGRVMRAFAGPPGPGRLLRSFWGLDARGGG
                     SALSREFLQSGDALLDSLFDDEPLKAALAWFGAQSGPPMSEPGTAPMVGFAALMHTLPP
                     GRAVGGSGALTTALVARLRSDGGVVSAGDAVTELRRDGDGWRVRTESGRNLAARTVIAG
                     THILTTLDLLERGGFAAGALADWRRRIRVGPGIGMVVRAATDALPRYPGAGPAESARGL
                     QLLVSDRRQLRLAHGAALAGELPPRPVVLAMSFSALDPSIAPPGEHQLSLWAQWHPYRL
                     ADGTDWTARADQEADRIIREVDTAAPGFANSIRDRFVQTPADLERELGLRGGNVMHVDM
                     SLDQMFFWRPLPELSGHRVPGAPGLYLTGASTHPGGGV"
     misc_feature    complement(5690..5707)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.92"
                     /tool="antismash"
     misc_feature    complement(5773..5783)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            5900..6529
                     /locus_tag="AWN90_RS34955"
                     /old_locus_tag="AWN90_34980"
     CDS             5900..6529
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006554154.1"
                     /locus_tag="AWN90_RS34955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_34980"
                     /product="DUF3153 domain-containing protein"
                     /protein_id="WP_156674605.1"
                     /transl_table=11
                     /translation="MPLLAGCLRVQVSMGVSSNDRVSGRIVAAVVPANDKDKGPQLKVP
                     DTLAAKVRVEPYTQDGYVGSQVYFDDLTFGEVQQLGALSDQTQGMFNLQFTRSGDLVTL
                     SGRADLKTVPAQGSDVQFTVAFPARVATTNGTREGDSIVSWKLPPGDVSTLRAEVSYAD
                     PNTRSFAGWAGIVGGITLAVAAVVAVLAYMTRNPAPKYPVGPRRGA"
     gene            6833..7969
                     /locus_tag="AWN90_RS34960"
                     /old_locus_tag="AWN90_34985"
     CDS             6833..7969
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014350108.1"
                     /locus_tag="AWN90_RS34960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_34985"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_231951778.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.7e-11,
                     bitscore: 41.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGAGAALALVNRVTVRQLGPVRASVIEPVTVCVPARDEAARLPG
                     LIADLRAQRGVSRLRVLILDDGSRDGTYAAAVAAVERDERFTVIATDTDPEPGWTGKNA
                     ACARLAEIAGVTADSAETPPGVLVFLDADVRLGPWAIAAAVGELRRVGAGLVSPWPYQR
                     AESVAEALVQPLLCWSWASTLPVSAANHTLRPSTAVSCGQFLAFDAKVYRAVGGHAAVA
                     ADVTEDLALARALRRAGHTTVLVAAGRVANTRMYRGATDLDAGYSRWLWSAYGSPLGSM
                     AVGAAAALAYWAPPLAALLGRGATRRAGLVGYTAAVTARLLARSLESGGFPAPVDIVAS
                     LAHPASIAAYLRLSARSHRLHRSGALSWKGRTLTARAV"
     misc_feature    7274..7276
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7982..8692)
                     /locus_tag="AWN90_RS34965"
                     /old_locus_tag="AWN90_34990"
     CDS             complement(7982..8692)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008714194.1"
                     /locus_tag="AWN90_RS34965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_34990"
                     /product="hypothetical protein"
                     /protein_id="WP_231951780.1"
                     /transl_table=11
                     /translation="MPDSLRRGLVRLAGALSAAAVSAVVAAGPASAAPPDPAAAIASTD
                     RAAGAGDLGAAYQTAIEGLQRLGIQPFLYPTGAAFCHEATTLGMVPALAGAVPGPWPKT
                     TVAVPGLDVSAVKAGQTMFAFVPYGLGPDGPDTSGMRVAWLNTTTGRGGLASMGPLSEV
                     VKAMVPPEVPASARPLAEQVVQTFFATALPMGGVRAVPVTTGSGTVLAAVFGSVRNGAR
                     TCYFLPTVGITTVA"
     gene            complement(8890..9888)
                     /locus_tag="AWN90_RS34970"
                     /old_locus_tag="AWN90_34995"
     CDS             complement(8890..9888)
                     /EC_number="1.5.1.20"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0006555 - methionine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019928301.1"
                     /locus_tag="AWN90_RS34970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_34995"
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="WP_082871624.1"
                     /transl_table=11
                     /translation="MSFDNARGRSTPGRLSRTPQVSGTPSVVGRLGPRPDGTIPFSVEF
                     NPPRDAANEARLWRAAREFERMHPAFVSMTYGAGGSTRDRTARVTGQLARETTLLTVAH
                     LTAVGHSVAELRSIMGTYADSGIRNLLVLRGDPPGDPLGEWQRHPEGLEYAEELVRLVR
                     GLGDFHVGVASFPQGHHRSPDLDHDTAHLCAKLRAGAEYSITQMFFDVDDYLRLRDRVI
                     ACDPIEGAKPIIPELMPITSLRTVQRAEELSGRPLPTRLRERLERAGGADPDANRAAVR
                     EVGIEIATEIAQRLIAEGAPCLHFITLNFAKATSEVLTNLGYTVTAAPVGA"
     misc_feature    complement(9852..9871)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 25.47"
                     /tool="antismash"
     gene            10001..11188
                     /locus_tag="AWN90_RS34975"
                     /old_locus_tag="AWN90_35000"
     CDS             10001..11188
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014350105.1"
                     /locus_tag="AWN90_RS34975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_35000"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_231951782.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.2e-49, bitscore:
                     166.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRAPRITVTMDDRLLAASNFWEVALPVGPSTPTRPAPTDAASLV
                     TAVEENLRLFFAGRRELVDELGPVFVSSADALADFVLRGGKRTRPAFAWTGWLGAGGDP
                     ADPHAAAVLRACSALELVQACALIHDDIIDSSRTRRGFPTVHTDFERRHREREWGGDPA
                     HFGISVGILIGDLALAWADDMVAAAGLKPAAYARFAPVWAAMRTEVMGGQLLDVHGEAG
                     ADDSVEAALRINRYKTAAYTIERPLHLGAALADADPDLIAAYREFGTDIGIAFQLRDDL
                     LGVFGDPEVTGKPSGDDLREGKRTVLVAEALRRADATDPEAAGLLRRSLGTDLSAAQVT
                     RLRETITGLGAVEEVERRIGELTERGLAALDSCSATPQARERLRAMAVAATTRVA"
     gene            11185..12762
                     /gene="crtI"
                     /locus_tag="AWN90_RS34980"
                     /old_locus_tag="AWN90_35005"
     CDS             11185..12762
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014983127.1"
                     /locus_tag="AWN90_RS34980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_35005"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_067591775.1"
                     /sec_met_domain="DAO (E-value: 1.1e-08, bitscore: 33.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVGGPTDRIVVVGAGLSGLSAALHLTGAGRAVTLLERADHPGG
                     RVGVYRGPDYEIDSGASVLTLPGVIHDTLAAVGAEAGAHGLRIHRLTPAYRARFADGST
                     IAVHSDPDAMAAEVERACGPAEARRYRRLREWLGRVYDAAYDQFMDTNFDSPLDMVAIP
                     EKRAALIELVRLGAFGRLGAKVGRILHDDRLARLFTFQALYAGTAPAQALAVYGAIPHM
                     DTSLGVYFPEGGMRSVTAALAAAFTAAGGRLELNTEATGIDYAAGRARRVRTADGRAFD
                     CDAVVLTADLGALDRFGIHRRLPLRASPSAFVAHGTVPAEVAARWPIPAHHTIDFGAAW
                     ADTFAEIAARPGRGRLMSDPSLLLTRPALTDPGLFVDRPTGRHEPLTLLAPCPNLVAAP
                     LNWDRLAPAYLRELLCTLENRGYRGIAGHFTVDHLDTPETWRAQGMLAGTPFSAAHVFR
                     QTGPFRPRNLPRTATNVVLAGCGTTPGVGVPTTLLSGKLAARRITGDPRHAVPGSGPTA
                     GVVFPATN"
     misc_feature    12091..12093
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12868..14448
                     /locus_tag="AWN90_RS34985"
                     /old_locus_tag="AWN90_35010"
     CDS             12868..14448
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019928298.1"
                     /locus_tag="AWN90_RS34985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_35010"
                     /product="alpha-(1->6)-mannopyranosyltransferase A"
                     /protein_id="WP_067596103.1"
                     /transl_table=11
                     /translation="METPESPRPAPLPVSHNLRWWMRVSADFLRSPEGHAALLGFWGAL
                     LITVGGLGAGAVRRRDPLLEHAHLSWLRFGHGYTLATIVVWVGVLAMIVAWVRLGRATI
                     GTGEHGSGVTLNELRAIVGIWIFPLLFAVPMFSQDVYSYLAQGALLRDGFDPYRIGPLQ
                     GNPGVLLDNVSPVWLTTTAPYGPIFLLLGRAITTVTGDNVVAGTIAMRLVMLPGLALMM
                     WAVPHLTKHLGGKPTVALWLAVLNPLVLIHLIGGVHNEMLMVGLMAAGIALVLEHHHVA
                     GIVVVAIGVAIKATAGVALPFLVWIWMIHERERRAAEHKGPLPHPIWTFAKIGGLGLSV
                     FAAVFALASAAAGVGIGWLTALSGSKLIINWLSLPTILAYMVSWVTPLRVDGAGSSVLI
                     ATRAICALALGVILVWTWWRFKRTEREAVLGILIAFVAIVILSPAALPWYYSWPLALAA
                     GFALSTPTLMLLVGLCTWLMLVFEPGGAIGLYNFWHVAAATFAAVVAALSLRTVDPLRL
                     RADTGKARP"
     gene            14445..15422
                     /locus_tag="AWN90_RS34990"
                     /old_locus_tag="AWN90_35015"
     CDS             14445..15422
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014983125.1"
                     /locus_tag="AWN90_RS34990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_35015"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_067591778.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.1e-101,
                     bitscore: 337.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.2e-61,
                     bitscore: 205.2, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVEQVVAGTAADPDAELAAAYRHCRSIAAAHGRTYFLATRLLA
                     PAQRPAVHALYAFARTVDDLVDYESFDAAGQVDRIEKRLRERLAHPLPPDPQDPVLSAV
                     AATIARYRIAPDHFWTFLDAMRMDIPGTPLFRSRYATMAELRGYMRGSAAAIGLQLLPI
                     LGTVGPRAAAEPAAAALGEAFQLTNFLRDIGEDLDRGRIYLPARELAAFGVDDDLLAHC
                     RWTGRTDIRLRRALAHLIATTRALYRVAEPGIELLQPRVRPAIRTAAVLYAEILAEIEE
                     SGYAVFDRRAVVPRRRRLWVAATSYAAAGVRAVGANRSDGMPRV"
     gene            15484..16869
                     /locus_tag="AWN90_RS34995"
                     /old_locus_tag="AWN90_35020"
     CDS             15484..16869
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019928306.1"
                     /locus_tag="AWN90_RS34995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_35020"
                     /product="3-deoxy-7-phosphoheptulonate synthase class II"
                     /protein_id="WP_067591781.1"
                     /transl_table=11
                     /translation="MNWTVDVPIDRLPELPPLPAELRRRLDDALSRPALQQPSWDRDQA
                     AKMRTVLESVPPICVPAEVEELRTLLAEVARGEAFLIQGGDCAETFADNTEPHIRGNIR
                     TLLQMAVVLTYGASLPVVKVARIAGQYAKPRSADTDSLGLKSYRGDMVNSLVAEAALRE
                     HDPSRLVRAYANASAAMNLVRALTGAGMADLHKVHDWNRDFVAQSPAGARYEQMAEEID
                     RALAFMNACRVQDPSLQAAKIYASHEALVLDYERAMLRLAENSAGDPVLYDLSAHFLWI
                     GERTRQLDGAHIALAELLANPIGLKIGPSTSPELAVEYVERLDPNNEPGRLTLVARMGN
                     GKVRDVLPPIIEKVQATGHQVIWQCDPMHGNTHESSTGYKTRHFDRIVDEVQGFFEVHR
                     ALGTHPGGLHIELTGENVTECLGGAQDISDLDLEDRYETACDPRLNTQQSLELAFLVAE
                     MLR"
     gene            16883..17182
                     /locus_tag="AWN90_RS35000"
                     /old_locus_tag="AWN90_35025"
     CDS             16883..17182
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS35000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AWN90_35025"
                     /product="hypothetical protein"
                     /protein_id="WP_067591784.1"
                     /transl_table=11
                     /translation="MHVVFRSPDTRHGEPADRTILRLLRDRDRDGVPSEVVLRDGSRLL
                     IFNISWGYDPAAVSAQVTTNISPAIGGVSVDVFSTAAVVAVNDPETGSPLLAVA"
     misc_feature    17012..17014
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17319..17636
                     /locus_tag="AWN90_RS35005"
                     /old_locus_tag="AWN90_35030"
     CDS             17319..17636
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014984751.1"
                     /locus_tag="AWN90_RS35005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_35030"
                     /product="hypothetical protein"
                     /protein_id="WP_231951784.1"
                     /transl_table=11
                     /translation="MTVAEELRSMSGGGPTALAQHESVVNGIPVSVLIERPEVDRAGRA
                     WRCRVRVVRGTGRIEQSQVVGTSAHEVLEQALELAATRLGISESELLSGASMGLDTDSD
                     R"
     gene            complement(17652..19628)
                     /gene="pknB"
                     /locus_tag="AWN90_RS35010"
                     /old_locus_tag="AWN90_35035"
     CDS             complement(17652..19628)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008715722.1"
                     /locus_tag="AWN90_RS35010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_35035"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_067591787.1"
                     /sec_met_domain="Pkinase (E-value: 1.9e-47, bitscore:
                     159.8, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDGRYRIDAPIARGGMSMVFRGVDTRLDRPVAIKVMDPKFAGDP
                     QFLTRFEFEARSVAKLKHPALVAVYDQGIDGEYPFLIMELVEGGTLRELLRERGPMPPH
                     AVRAVAEPALAAIGVAHAAGLVHRDVKPENVLISDSGEVKMADFGLVRAVAGSNLTSAS
                     VILGTAHYLSPEQVTAGSADARSDVYSFGILIFEMLTGRTPFTGDTSLGIAYQRVEKDV
                     PSPSRFIAGVPPEFDELIARATAREPAHRFADATEMAVELRRIAAELRLPDYRVPAPRE
                     SAEHLSAQYRVPPVPPAPPRERAEPRRIPADATTRLAADAPAPQRTRVMTATQPRAESD
                     GYTGRVAHAPEPPEPYHDPYRPDRGHTGRGRVLFWVGLVIALALLLGIGGWWLGVERYS
                     AVPAIAGMDSQRATAALHDAGFSTTMRGKASDTVPVGGVLGTDPSAGTRVVKGSSVAVL
                     VSSGKPQVPKFQEGQDLKTVEQLIRDAGLQPVDAGERPSTAPKGAVFQLEPEPGTVLPT
                     GAAVKIYRSKGSQPVQLPEVRGRTVDEARAMLQSAGITVRDTRNDFDPRIKSGQVIGTD
                     PGAGTRALSGDAVTLIVSNAVQVPDVTGMTAVAARTQLEQLGLRVVLNQVFASDRGMVR
                     IQAPFAGASVAPGATVTLTVLPI"
     misc_feature    complement(18822..18824)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            19791..20159
                     /locus_tag="AWN90_RS35015"
                     /old_locus_tag="AWN90_35040"
     CDS             19791..20159
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007297456.1"
                     /locus_tag="AWN90_RS35015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_35040"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_067591790.1"
                     /transl_table=11
                     /translation="MSAFPCSDDVLSESVTLLPLPDVADQLGIAVTRVHQMLRDHQLIA
                     VRREGITGIPKDFFDPDGAVVKPLPGLITVMRDAKYTNEEILEWIYTVDETLPGRPIDA
                     LHGPLAREVVRRAAAEPF"
     misc_feature    complement(19796..19809)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.45"
                     /tool="antismash"
     misc_feature    complement(20260..20275)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.0"
                     /tool="antismash"
     misc_feature    20276..20290
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.18"
                     /tool="antismash"
     misc_feature    complement(20280..20293)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.95"
                     /tool="antismash"
     misc_feature    complement(20280..20296)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.76"
                     /tool="antismash"
     misc_feature    20280..20296
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.45"
                     /tool="antismash"
     gene            20280..>20654
                     /locus_tag="AWN90_RS35020"
                     /old_locus_tag="AWN90_35045"
                     /pseudo=""
     CDS             20280..>20654
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012688083.1"
                     /locus_tag="AWN90_RS35020"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_35045"
                     /product="polyadenylate-specific 3'-exoribonuclease AS"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRYFYDCEFVEDGITIDLISIGVVCEDGREYYAVSTEFDPDRAGP
                     WVRRHVLPKLPEPSSPLWRSRERIREDLYAFLVPRPTVEPQLWAWVSAYDHVALCQLWG
                     SMVDLPTALPRYTNELRQHWD"
     gene            complement(20795..21520)
                     /locus_tag="AWN90_RS35025"
                     /old_locus_tag="AWN90_35050"
     CDS             complement(20795..21520)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014350079.1"
                     /locus_tag="AWN90_RS35025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_35050"
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="WP_067591796.1"
                     /transl_table=11
                     /translation="MFYWLLKYVFPGPFMHLYNRPKAEGVEHIPADGPAILAGNHLSFT
                     DWLFTPLMSPRRITYLAKAEYFTTPGLKGRLQKFFFSGTGQYPIDRTGADAAVDALNTA
                     RRLLEQGRLVGLYPEGTRSPDGRLYKGKTGVARLALETGVPVIPVALIGTDEVCPPGPF
                     TWRRRRVTVKFGAPIDFSRYEGMGGNRFVERAVTDEIMYELMRMSGREYVDVYAASLKK
                     GVPSGPRPDADRVPETMAS"
     gene            complement(21665..22783)
                     /locus_tag="AWN90_RS35030"
                     /old_locus_tag="AWN90_35055"
     CDS             complement(21665..22783)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005247677.1"
                     /locus_tag="AWN90_RS35030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_35055"
                     /product="ROK family protein"
                     /protein_id="WP_082871625.1"
                     /transl_table=11
                     /translation="MTTRIGREAPLTVGIDVGGTNIRASVVDGAGEVLDTVQAPTPHSE
                     QALEDGLERAVRELCARHPIGAVGLAVAGFVDETRSSVRFAPHLPWEDTPVARRLTDRL
                     GLPVILEHDANAAMWAEYRFGAAAGAHNGVLVAIGTGIGAALLVGGRLYRGSFGVAPEL
                     GHLQVVPHGRACPCGKRGCWERYCSGTALVDTALEMLATDPMSSTILARDAARDPGSLT
                     GRRVAGAAQDGDPVALRVMAEFARWLGLGLAFVSDIFDPDLIVIAGGVSSSAPMFLDDA
                     REHYAAAITGARHRPLARIRTTQLGEAAGMVGAAELARAALVSERIGAPAEKPTPGAKS
                     TAKTSGKSGAGRRSSTAAGRSPAADGKAGARR"
     gene            complement(22780..23349)
                     /locus_tag="AWN90_RS48680"
     CDS             complement(22780..23349)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011208245.1"
                     /locus_tag="AWN90_RS48680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_231951785.1"
                     /transl_table=11
                     /translation="MSDGAGGRSGREWVRGEPVGRRTAPEDTATDETPGDSGGEARTDA
                     ADHDEAAHGDNFAEFAEELRLLAETILERVEPVLRQASADGRTEWDSCSWCPVCAAAAL
                     VRGQHHDVVAALAEHGTAIVTVLREALAGVPVEPIFPPDETSDSRNAGDAPGTKHGTMG
                     RMSATTQPRRDRGKSRYVPIPVQIKA"
     gene            complement(23346..24587)
                     /locus_tag="AWN90_RS35040"
                     /old_locus_tag="AWN90_35065"
     CDS             complement(23346..24587)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006933348.1"
                     /locus_tag="AWN90_RS35040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_35065"
                     /product="ArsA family ATPase"
                     /protein_id="WP_331713396.1"
                     /transl_table=11
                     /translation="MTTTTRLELFVGKGGVGKTTLACATAIAHTRGGARVLVASLDQAH
                     SLGDALGFRFPHDPGAVTGVRTVRPGLDVIEIDSLALLEDRFRDAARMLSGAGHEHGID
                     PAALDPAELTGLPGVQELLMLTEIAQFAGDEDWDVIVVDCPPSADMLRIVTAPDTLLGY
                     LERIWPAHARMLDATGTDLRRAVLATTVERIAAAVTEARDLLADRERTGARLITVPERV
                     ALAESARVRSAAALLGLRLDEVVVNKVLPPVPPADPAAHPAVRWYLDRHAEQQQVLAEL
                     RRRMPDVPVAIVEHSGAEPVGVASLSAMAVSPPDPMLGGANADFARSGAPQVRLTSGSG
                     LDSVFTLRLRLPVVDPATLRLGRVEDDLIVGADGVRRRLRLAPVLRRCTVDGAELDDGD
                     LVVRFRPDAEVWPQ"
     gene            complement(24584..25021)
                     /locus_tag="AWN90_RS35045"
                     /old_locus_tag="AWN90_35070"
     CDS             complement(24584..25021)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (3-144). E-value:
                     2.3e-15. Score: 49.2. Matches aSDomain:
                     nrpspksdomains_AWN90_RS35045_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010594359.1"
                     /locus_tag="AWN90_RS35045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_35070"
                     /product="SRPBCC family protein"
                     /protein_id="WP_067591798.1"
                     /transl_table=11
                     /translation="MADRTQRSITIDAPSDRVMAVIADLESYPEWVSAARSVEVLDKFG
                     DGRAHTARFVLDAGVVKDTYVLSYTWRPDGKAVSWQLIEGELQKAQDGRYELIDQPDGT
                     TQVVYELTVDLTIPMIGMFKRKAEKVITDTALKELKKRVEG"
     aSDomain        complement(24590..25012)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AWN90_RS35045_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="2.30E-15"
                     /label="AWN90_RS35045_Polyketide_cyc2.1"
                     /locus_tag="AWN90_RS35045"
                     /protein_end="144"
                     /protein_start="3"
                     /score="49.2"
                     /tool="antismash"
                     /translation="RTQRSITIDAPSDRVMAVIADLESYPEWVSAARSVEVLDKFGDGR
                     AHTARFVLDAGVVKDTYVLSYTWRPDGKAVSWQLIEGELQKAQDGRYELIDQPDGTTQV
                     VYELTVDLTIPMIGMFKRKAEKVITDTALKELKKRVE"
ORIGIN
        1 cggggtgcgc gaggccgatc gccgcgcgag cacctgcttg accagcttgt cctccagcga
       61 ctgataggac atgacgacga tgcggccgcc cacctcgagc gcgtccaggg cggcgggcag
      121 agccagttcc agcgattcca gctctcggtt gacctcgatg cgcagcgcct ggaaggtgcg
      181 cttggcggga tgccccccgg tgcggcgcgt cgcggccgga atggcgtcgt agagcagctc
      241 caccagctgg gcactggtgg tgaacggccg ctgcgcacgg cgcttcacga tctcggaggc
      301 gatgcggccc gcgaatcgtt cgtccccata gtttttcagg atgcgggcca ggtcgccgtg
      361 gtcgtaggtg ttgagcacgt cggcggcggt gagctcggcc gtcgggtcca tgcgcatgtc
      421 cagcggcgcg tcgacggagt aggcgaagcc gcggtcggcc tcgtcaagct gcatggagga
      481 cacgcccagg tccatgagga tcgcgcgcac cgaggcggtg ggggcgagcc cggcctgccg
      541 cagcgcgtcg gcgatgccgt cgtagcgggt gtgcaccagg gtgatccggt ccgcgaacgg
      601 ccgtaatcgc tcgcccgcga gccgcagggc gtcggtatcg cggtccaggc cgaccaggtg
      661 gatatcgggg taggtgcgca ggaagtactc ggagtggccg ccgaggccga gggtggcgtc
      721 gatcatgaca ccgccggaag tcagtgcggg accgaggatt tcgtcggctc gacggagcag
      781 gaccggaaca tggcgggggg tgtggttctc atggttcacc tcgacctccc ggaccttgct
      841 gacggtgtcg aacgaccacg gtcgctgacg attcggactc actcgtcggt ggtgaatgcc
      901 ccgtggtctc tgaccgaagc acggcacctg gcgttgggga agtacgtcag ggtccgcgtc
      961 gggcagaggc cacagggcat tcaccctcgc tcggactaga agattccgcc cagcgactcg
     1021 tctctggcca gcgagtaatc ctcctcgtgt tcggcgaggt aggactccca cgcctgcttg
     1081 tcccaaatct cgaggaagtc gaccgaaccg atgaccacgc agtccttgga caggctcgcg
     1141 tagcgccggt gctcgatcga caacgtgatc cggccctgtg cgtccggacg ttgctcatcg
     1201 gtggaggcgg ccagggcgcg gacgaaagcc cttgcctgcg ggttgcttcg ggacgccgcg
     1261 gcggcgcgcc gcgcgagcgc ggcgaactcc tccttgggat acacggcaag gctgtggtcc
     1321 tgccctttcg tgaccatcaa ccctcccgcc agttcgtctc gaaacttcgc cggcaacgtc
     1381 agtcgccctt tgtcgtccag ccgcggtgtg taggtaccga gaaacacgtc tcgacacctc
     1441 ccgttcgatc accccgtctg gtcggcctcc tcagtgcgcg ctccacatta ccccactttc
     1501 ccccactttc aatcgaaagc cgcggtgatc tcgatccctg cgcagccgat tgcccaggtc
     1561 acaccagcta tcaccgaggt ggggagattt cttcgagttc cccgacacgc gaccccgaca
     1621 acatgggtga cccgacaacc atcagcaaac ccgctgatcg catcgggtca ccgggtgcgg
     1681 tggggcgtgg tgggggccgc gcgtggggag gtgtggggag tcctggagga agggggtgga
     1741 cgggtccgaa cacccaccga caaaaattga cacgccgcgc gatgcacggc gtgtcgtgtc
     1801 tgttttcggt tgttcacggg gtgggcgcgc gaacgcctcg gaattccgga tccgggcgac
     1861 cggacccgga acggtcagcc accctcttcg aacctgcggc ggaagcggtc ctccatgcgg
     1921 gcggagaaac cgccgccgga cttgcgcggc ttgctcttgc cgccgcccac gggcccggcc
     1981 ggacccgacg gcgactcacc accgcgatgc ccggagccga gcgcgccgcg gccgcccagc
     2041 aacaacagca cgcccgcggc gaacatcacg atgaaaccca gcaggctgat gaccgggaag
     2101 ccgcccggct tcaccggtag ggcgatgccc gcgatgagaa gaacgaggcc gaggacgaac
     2161 agagcggccg cctgaagtct gcgtcttccg gtggccgaac gtagccggcc gccgcggacg
     2221 gacgaggcga atttggggtc ctcagcatag agagcgctct cgatctgttc gagcatgcgc
     2281 tgctcgtgct cggagagtgg cacggtacct cccccggcac taggtcgtgg tggtcgcctc
     2341 cgggtagacg acaagtagcc gaccttggcg gctacctgcc accaatgata cgagttcgat
     2401 cagtgcggta ccacctcctc cgccgatgtt caggccgtgc cgtcggcgag ccacccggtg
     2461 atcgggcgca ggcgcgcctc ggtggccagg agatcttcca cgtcgtgtag gaacgcccct
     2521 acgcgggaag cgaactcgtc ggcgcggcgc gcgtcgaccg ggcggtcgag ccccgcttcc
     2581 agcgccgcgc gggtctcgga gtaggaactg aagtagtcgg tccacatcac gaattcgggc
     2641 gctgcctgct gcatcagcac ccaggcgttg cgggagcggg cacggggcgc ccggtcggcg
     2701 cccgagagtg cgagcaccgc tcccgcaccc cgcagcgccg ccaggtacgc cgtgcggaac
     2761 cgttcgcgcg ggtcggcctc ggcgcccgcc tgcagcagca gcgcatcggc acgatccagc
     2821 aaaccgcccg cccgtccgga acgccccgga tgttgcatcc gaccagccat cgcggtacct
     2881 ccacaccctt cgcacacccc gattcggcgg gtacatcgcc gaccacgccg accgaacagg
     2941 tattcgaacg tttcaatgag tgtgaatata gagacgacca ccgacaaact tccgcgcccg
     3001 cgctcgtagt cccgatcctc gagcggagcg cccgcgtcga acgagagccg cgccgccgaa
     3061 gctatgaccg ccctcagacc ccaccacccc caccactccc ccgcacccgt cgtcgtcgat
     3121 ctgtcggccg ccaccctgcg cgcccggctg cacgacgcgc tgtcggtgta cgtggccgcc
     3181 atggactatc cgcgcggcac cgagcatcac cgcgcgccga tgtggaccga gcacaccacg
     3241 cgccccggct ggcaggcggt gggcgcggtg ctaccggacg acagcgggga attcgatctg
     3301 cgcaccgcgc cgctggtggc gatcgcctac ggctatcacg gtgcgccgca ccagtggtgg
     3361 catcagcagg tgcacagcgg catgcgccgg tcgggctggc cggaatacgc ggcgcgcgac
     3421 ctgctttcgg actacttcga gctcaccgag ctgcacgtgc atcccaccgc gcagggtcgc
     3481 ggcatcggcg agacgctgct gatgcggctg ctgcgcaacc ggaccgagcg ggcggcgctg
     3541 ctgtccacgc cggaggtgga ccgggagaac aaccgggcct ggcggctgta tcggcgccag
     3601 ggattcaccg atgtggtgcg gcatttcgtg ttctccggcg acacccgccg gttcgcggtc
     3661 ctggggcggc ggctgccgct ggaagcgccg tcgcggtgac ggtgctgatc gtcggctccg
     3721 gccacaacgc gctggtggcc gcctgctatc tggcgcgggc cgggcaggcg gtggaggtgc
     3781 tcgagcgcga cgaggtgctg ggcggggcgg tgtcgacggt gccgcggttc cccgggcatc
     3841 tggtggaccg cggctcgtcg gcgcacatca tgatccggca caccgggatc gtcgaggagc
     3901 tggaactgga tcggttcggg ctgcgctaca tcgattgcga tccctggggt ttcgcgcccg
     3961 ccccggccgg aaccgagcgg ccgcccctgg tgttccatcg cgatctggac cgcacctgcg
     4021 cctcgatagc ggcggcctgc ggggcacggg aggcggaggc ttatcggcgt ttcgtgcggg
     4081 tgtggggtcc gcgcagcggg cgggtgatgc gggcgttcgc cgggccgccg ggtccgggcc
     4141 ggttgctgcg ctcgttctgg gggctggacg cgcggggcgg cgggagcgcg ctgtcgcggg
     4201 aattcctgca atccggtgat gcgttgctgg acagcctgtt cgacgacgaa ccgctgaagg
     4261 cggcgctggc ctggttcggc gcgcagtcgg ggccgccgat gtcggagccg ggcaccgcgc
     4321 cgatggtcgg tttcgcggcg ctcatgcaca cgctgccgcc gggacgcgcg gtcggcggca
     4381 gcggcgcgct gaccacggcc ctggtggcgc ggctgcggtc cgacggcggg gtggtgtcgg
     4441 ccggggacgc ggtcaccgag ctgcgccgcg acggcgacgg ctggcgggtg cgcaccgagt
     4501 ccgggcgaaa cctggccgcg cgcaccgtga tcgcgggcac ccacatcctc accaccctgg
     4561 acctgttgga gcgcggcgga ttcgccgcgg gcgcgctcgc cgactggcgg cggcgcatcc
     4621 gggtggggcc cgggatcggc atggtggtgc gcgcggcgac cgacgcgctg ccgcgctatc
     4681 ccggcgccgg gcccgcggaa tccgcacgcg gactgcaact tctggtcagc gatcggcgac
     4741 agctgcggct ggcccacggc gcggcgctgg cgggcgagct gccgccgcgc ccggtggtcc
     4801 tggccatgag cttcagcgcc ctggatccct ccatcgcgcc gcccggcgaa catcagctgt
     4861 cgctgtgggc gcagtggcat ccgtaccgcc tggccgacgg caccgactgg accgcacgtg
     4921 ccgaccagga ggccgaccgc atcatccgcg aggtcgacac cgccgcaccg ggtttcgcga
     4981 actcgatccg cgaccgcttc gtccagacac ccgccgacct ggaacgcgaa ttgggcttgc
     5041 gcggcggcaa tgtcatgcac gtcgacatgt ccctggacca gatgttcttc tggcgtcccc
     5101 tcccggaact gtccggccac cgcgtccccg gcgcacccgg cctctacctg accggcgcat
     5161 ccacccaccc cggcggcggc gtaggttgcg tagggccagg gtggcggcgg tgctcggcgt
     5221 ggccggggct gccggggctg ccgcagattc cgtggaccaa ctatctgggg tggctgggtg
     5281 tggcgctgct gatggcggtg ctgttggagg cgctcgatcg cgggagccca cgccgggcgt
     5341 ccacgattct cgttccggtg gtggtgtttc tgtggacctg gctggggtcc gcgctggcgc
     5401 atgcggtgtt cctggggttg ccggtgtccg cggggtacgg gttcgcgggt ctgggattac
     5461 tggggattcc cttggtgtgg gccatatttc gtgattcctc cccgcgattt cggcgtgctt
     5521 tcggccggaa tccaccgtga gttcccggcc aaaagcacgc cggtaacagg agagtgggca
     5581 cgccgggaac aggagagtga gcacgccagg acatgagagt gggcacgccg ggaacgggag
     5641 agtgggcaca ccaggaacgg gagagcgagc acaccaggaa caggagaggg tcacaccggg
     5701 atcacaatgg tcggcgcgtc ggaggtacga cgcgccgttg gggtgcggcc cgtcgtaggc
     5761 gctccggtcg gcgtgtcatg gcacgatgtg agccgtgcag ccgagtccga caactcccct
     5821 ccccgccgcc gcgagcgcgt cccagccgcg gcggcgccgt tatcgtgcct ggtccgtcct
     5881 gttcttggcg gcgtttgtga tgccgctgct ggccggctgc ctgcgggtgc aggtgtcgat
     5941 gggcgtgtcg tcgaacgatc gggtgtcggg gcggatcgtg gccgccgtgg tgcccgccaa
     6001 cgacaaggac aaggggccgc agctgaaggt gcccgacacg ctggccgcca aggtgcgggt
     6061 ggagccgtac acgcaggacg ggtacgtggg cagccaggtc tatttcgacg atctgacctt
     6121 cggcgaggtg cagcagctgg gcgcgctgtc ggatcagaca cagggcatgt tcaacctgca
     6181 gttcacccgc tccggcgacc tggtcacgct gtccgggcgg gcggatctga agaccgtccc
     6241 ggcgcagggc tcggatgtgc agttcaccgt cgccttcccg gcccgggtcg ccaccaccaa
     6301 cggcacccgc gagggcgatt ccatcgtgtc gtggaagctg ccgcccggtg acgtcagcac
     6361 gctgcgcgcc gaggtgagct acgccgaccc caacacgcgc tcgttcgcgg gctgggccgg
     6421 gatcgtcggc ggcatcaccc tcgcggtcgc cgccgtcgtc gcggtcctgg cctacatgac
     6481 ccgcaacccc gccccgaagt acccggtcgg cccgcggcgc ggggcctgac cgggcgcgat
     6541 cccgcggcgg gacgacggcg cgccgacgtg tgtcgcgatc ccggcggggc gagtgactgt
     6601 gcgagccacc cgggcgggac tatcctgcga gccatgggcg cgcacgcgag cgcccgccga
     6661 tccaagcgcc ggcgaaaccg aactctcgag cgacccggag gacaccctgc agccgcgcaa
     6721 cgcacgaccc gcacgaccgc tgtcgcgggc cggtataccg gccctcgcac ggtggtcgcg
     6781 tgaccgtcgg atcggttgcg gcactgcgct tctggtcggt gcgggcgccg cggtggccgg
     6841 ggccggtgcg gcgctggccc tggtgaatcg ggtgacggtg cgccagctcg ggccggtgcg
     6901 cgcctcggtc atcgagccgg tgacggtgtg cgtgcccgcg cgcgacgagg ccgcgcggct
     6961 gccggggctg atcgcggatc tgcgggccca gcgcggcgtt tcgcgcctgc gggtgctgat
     7021 tctcgacgac ggctcccggg acggcaccta cgccgccgcg gtggccgcgg tcgagcgcga
     7081 cgagcggttc accgtgatcg cgaccgacac cgatcccgag ccgggctgga ccggaaagaa
     7141 cgccgcctgt gcccggctgg ccgaaatcgc cggggtgaca gcggattccg cggagacacc
     7201 gccgggcgtg ctggtcttcc tggacgcgga cgtgcggctc ggcccgtggg cgatcgcggc
     7261 ggcggtcggc gaattacgcc gcgtgggagc gggtttggtg tcgccgtggc cgtaccagcg
     7321 tgccgagtcg gtggccgagg ccttggtgca gccgctgctg tgctggtcgt gggcgtcgac
     7381 gctgccggtg tcggcggcca atcacaccct gcgcccctcg accgcggtgt cgtgcgggca
     7441 gttcctggcc ttcgacgcga aggtgtaccg ggccgtcggc gggcatgccg cggtggccgc
     7501 cgatgtcacc gaggatctgg cgctggcccg cgcgctgcgc cgcgccgggc acaccaccgt
     7561 gctggtcgcc gcgggccgcg tcgccaacac ccggatgtac cggggcgcaa cggatctcga
     7621 cgccggatac agccgctggc tgtggtcggc ctacggttcg ccgctgggca gcatggccgt
     7681 gggcgccgcc gccgcgctgg cctactgggc gccaccgctc gccgcgctgc tcggccgggg
     7741 cgcgacccgc cgcgcgggct tggtcggcta cacggccgcg gtcaccgccc gcctgctggc
     7801 ccgatccctc gaatcggggg gattccccgc tcccgtggat atcgttgcgt ccctggcgca
     7861 tccggcctcc atcgccgcct acctccgcct ctcggcgcgc tcccaccgcc tccaccgcag
     7921 cggggccctg tcctggaagg gccgcaccct caccgcccgc gcggtctagc ccgccggaaa
     7981 ctcaagcgac cgtggtgatt ccgacggtcg ggaggaagta gcaggtgcgg gcgccgttgc
     8041 ggacggagcc gaagacggcg gcgagaacgg tgccggaacc ggtggtcacc gggacggcgc
     8101 ggacgccgcc catgggcagg gcggtggcga agaaggtctg gacgacctgt tcggcgaggg
     8161 ggcgggcgga ggcggggacc tcgggcggga ccatggcctt gacgacctcg gacagggggc
     8221 ccatgctggc gagtccgccg cggccggtgg tggtgttgag ccaggccacc cgcatgccgg
     8281 aggtgtcggg gccgtcgggt cccaggccgt agggcacgaa ggcgaacatg gtctgccccg
     8341 ccttcaccgc ggagacatcc aggcccggca ccgcgacggt ggtcttcggc cacgggcccg
     8401 gcacggcacc ggccagcgcg ggcaccatac cgagggtggt ggcctcatgg cagaacgccg
     8461 caccggtcgg atacaggaac ggctgaatgc ccagccgctg caagccctcg atggcggtct
     8521 gataggcggc acccagatcg cccgcgcccg cggcccggtc ggtgcttgcg atggcggcgg
     8581 ccggatcggg tggcgcggcg gaagcggggc ctgcggcgac gaccgccgag accgcggcgg
     8641 cgctcaacgc accggcgagc cgaacgagcc cgcgccgcaa ggaatccggc acacgacgct
     8701 ccggaacgga atcaccacga acgagactgc acagcacggc catcgggggc gctcctgatc
     8761 gtcacggtcg aacgcggtcg gcacggtcgg ggcgaccgta ccgcgcccga gtgagcggac
     8821 cgctgcgaaa cgccgggtga ttccggccaa aagcatgccg gaatcgtagt ggcggggagg
     8881 gcggggcagt caggctccga ccggggcggc cgtgaccgtg tagccgaggt tggtgaggac
     8941 ctcgctggtg gccttggcga agttcagggt gatgaagtgg aggcaggggg cgccttcggc
     9001 gatgaggcgc tgggcgattt cggtggcgat ttcgatgccg acctcgcgga ccgcggcgcg
     9061 gttggcgtcg gggtcggcac cgcccgcgcg ttccaggcgc tcgcgcagcc gggtgggcag
     9121 cgggcggccg gacagttcct cggcgcgctg cacggtgcgc agcgaggtga tgggcatgag
     9181 ttccgggatg atcggcttgg cgccctcgat cggatcgcac gcgatgaccc ggtcccgcag
     9241 ccgcagatag tcgtccacgt cgaagaacat ctgggtaatc gaatactccg cgcccgcacg
     9301 cagtttcgcg cacaggtggg cggtgtcgtg gtcgaggtcc ggggagcggt gatgcccctg
     9361 cgggaacgac gccaccccga cgtggaagtc gccgagcccg cgcaccaggc ggaccagttc
     9421 ctcggcgtac tccaggccct cggggtgccg ctgccactcg ccgagcgggt cgccgggcgg
     9481 atccccgcgc agcaccagca ggttgcggat gcccgagtcg gcgtaggtgc ccatgatgga
     9541 ccgcagttcg gccacgctgt gcccgaccgc ggtgagatgg gcgacggtca gcaacgtggt
     9601 ctcgcgcgcc agctgaccgg tgacgcgggc ggtacggtcg cgggtggagc cacccgcgcc
     9661 gtaggtcatc gagacgaacg ccggatgcat gcgctcgaat tcgcgggccg cgcgccacaa
     9721 tcgggcctcg ttggcggcgt cgcgcggcgg attgaattcc accgagaacg gaatcgtccc
     9781 gtcgggccgc ggcccgagcc gacccacgac ggagggagtt ccggagacct gcggcgtccg
     9841 ggaaagtcgg cctggggtcg aacgtccccg tgcgttgtcg aaactcaccg gtccagtgta
     9901 agtgcccggt cgcggccctt atccgcgact ccgacgattt gctactgccc ggtaggcgtg
     9961 tcggggcggc acggcggacg cagtatcgtt ccctgcggag gtgccgcgcg cgccccgaat
    10021 caccgtcacc atggacgatc ggctgctcgc cgcgtcgaat ttctgggagg ttgcgttgcc
    10081 cgtcggaccg agcaccccga cccgtccggc gccgaccgat gcggcatctc tcgtgacggc
    10141 cgtcgaagag aatctgcggc tgttcttcgc cggtcgccgg gaactcgtcg acgagttggg
    10201 cccggtgttc gtgtcctccg ccgacgcgct ggccgacttc gtgctgcgcg gcggcaagcg
    10261 cacccgtccg gccttcgcct ggaccggctg gctgggcgcg ggcggcgatc ccgcggaccc
    10321 gcacgcggcc gcggtgctgc gcgcgtgctc ggcgctcgag ctggtgcagg cgtgcgcgct
    10381 gatccacgac gacatcatcg actcctcccg cacccggcgc ggcttcccga ccgtgcacac
    10441 cgatttcgag cgccgccacc gcgagcgcga atggggcggg gacccggcgc atttcggcat
    10501 cagcgtcggc atcctgatcg gcgatctcgc gctggcctgg gccgacgaca tggtggccgc
    10561 cgcgggcctg aaaccggcgg cctacgcccg cttcgccccg gtgtgggcgg ccatgcgcac
    10621 cgaggtgatg ggcgggcagc tgctcgacgt ccacggcgag gccggggccg acgactcggt
    10681 ggaggcggcg ctgcggatca accgctacaa gaccgccgcc tacaccatcg agcgcccgct
    10741 gcacctgggc gcggcgctgg ccgacgccga cccggatctg atcgcggcgt atcgcgaatt
    10801 cggcaccgat atcggcatcg ccttccagct gcgcgacgat ctgctcggcg tattcggcga
    10861 tcccgaggtg accggcaagc cctccggcga cgacctgcgc gagggcaagc gcacggtgct
    10921 ggtcgccgag gcgctgcgcc gcgccgacgc caccgacccg gaggccgcgg ggctgctgcg
    10981 ccgctcgctg ggcacggacc tgtcggccgc gcaggtgacc cggctgcgcg agacgatcac
    11041 cggcctcggc gcggtcgagg aggtggagcg gcgcatcggc gagctcaccg agcgcggcct
    11101 ggcggcgctg gactcctgct cggcgacgcc gcaggcacga gaacggttgc gcgccatggc
    11161 ggtcgcggcg accacccgcg tcgcgtgaga accgtcggcg ggcccaccga ccggatcgtg
    11221 gtggtgggcg cggggctgtc cgggttgtcg gcggcgctgc atctgaccgg cgcggggcgg
    11281 gcggtgacgc tgctcgagcg cgccgatcat ccgggcgggc gggtcggggt gtatcgcggg
    11341 cccgattacg agatcgactc cggcgcttcg gttctcaccc tgccgggggt gattcacgac
    11401 acgctggccg cggtgggcgc cgaggcgggg gcgcacggcc tgcgcatcca ccggctcacg
    11461 cccgcctatc gcgcccggtt cgcggacggg tcgaccatcg cggtgcactc cgatcccgac
    11521 gccatggccg ccgaggtgga gcgcgcgtgc gggcccgccg aggcgcgccg gtaccggcgg
    11581 ctgcgggagt ggctgggccg cgtctacgac gcggcctacg accagttcat ggacaccaac
    11641 ttcgactcgc cgctggacat ggtcgcgatc ccggagaagc gggcggcgct gatcgaactc
    11701 gtccggctcg gcgcgttcgg ccgcctcggc gcgaaggtcg gccgcatcct gcacgacgac
    11761 cggctggccc ggctgttcac cttccaggcg ctctacgcgg gcaccgcgcc cgcgcaggcg
    11821 ctggccgtgt acggcgcgat cccgcacatg gacacctcgc tgggcgtgta cttccccgag
    11881 ggcgggatgc ggtccgtcac cgccgccctc gcggccgcct tcaccgcggc cggtgggcgg
    11941 ctggagctga acaccgaggc caccggcatc gactacgccg ccgggcgggc gcggcgggtg
    12001 cgcaccgccg acggccgcgc gttcgactgc gacgccgtgg tgctcaccgc ggatctgggt
    12061 gcgctggacc ggttcggcat tcaccgccga ttacccctgc gcgcctcgcc gtcggcgttc
    12121 gtcgcgcacg gcaccgtccc cgccgaggtt gccgcccggt ggccgatacc ggcgcaccac
    12181 accatcgatt tcggcgcggc ctgggcggac acgttcgccg agatcgccgc gcgccccggc
    12241 cgcggccggt tgatgagcga tccgtcgctg ctgctgaccc gcccggcgct gaccgatccg
    12301 ggcctgttcg tcgaccgacc caccggccgc cacgaaccgc tgacgctgct cgcgccgtgc
    12361 ccgaatctgg ttgcggcgcc gctgaactgg gaccggctcg cgcccgccta cctgcgcgaa
    12421 ctgctgtgca cgctggagaa tcgcggctac cgcggcatcg ccgggcactt caccgtcgac
    12481 cacctggaca cgccggaaac ctggcgggca cagggcatgc tcgcgggcac cccgttctcg
    12541 gcggcgcacg tgttccgcca gaccggcccg ttccggccgc gcaatctgcc ccgcaccgcc
    12601 acgaatgtgg tgctggccgg ttgcggaacc acccccggtg tcggggtgcc gaccacgctg
    12661 ctgtccggca agctcgccgc ccggcgcatc accggtgatc cccggcatgc cgtgcccgga
    12721 tccgggccga ccgccggagt agtgttcccg gcaaccaact aaactgtgcg cgacctattg
    12781 accgcggtat cgcaaccgca ccgactgttc ggggggaacc gacgaactat gccgaccccc
    12841 gagccggata ccgccaccgt ggagacgatg gagacccccg agtccccccg ccctgccccg
    12901 ctgccggtat cgcacaacct ccgctggtgg atgcgtgtct ccgccgactt cctccgtagc
    12961 cccgagggcc atgccgcgct gctcgggttc tggggggcgc tgctgatcac cgtcggcggc
    13021 ctgggcgcgg gcgcggtccg ccgccgcgac ccgctgctcg agcacgcgca cctgtcgtgg
    13081 ctgcgcttcg ggcacgggta cacgctggcc accatcgtgg tctgggtggg tgtgctggcg
    13141 atgatcgtgg cctgggtgcg gctggggcgc gcgaccatcg gcaccggcga gcacggttcc
    13201 ggggtgacgc tcaacgagct gcgcgcgatc gtcggcatct ggatcttccc gctgctgttc
    13261 gcggtgccga tgttcagcca ggacgtgtac tcgtatctgg cgcagggcgc gctgctgcgc
    13321 gacggcttcg acccctaccg gatcggcccg ctgcagggca atcccggtgt gctgctggac
    13381 aatgtgagcc cggtgtggct caccaccacc gccccctacg gcccgatctt cctgctgctg
    13441 ggccgcgcga tcacgacggt caccggcgac aacgtggtgg cgggcacgat cgccatgcgg
    13501 ctggtcatgc tgcccggcct ggcgctgatg atgtgggcgg tcccgcatct gaccaagcac
    13561 ctgggcggca agccgaccgt cgcgctgtgg ctggcggtgc tgaacccgct ggtgctgatc
    13621 cacctgatcg gcggcgtgca caacgagatg ctgatggtcg gcctgatggc cgcgggcatc
    13681 gcgctggtgc tcgagcatca tcacgtggcc gggatcgtgg tcgtcgccat cggcgtggcg
    13741 atcaaggcga ccgcgggcgt ggcgctgccg ttcctggtgt ggatctggat gattcacgaa
    13801 cgagaacgcc gggcggccga gcacaagggg ccgctgccgc acccgatctg gaccttcgcc
    13861 aagatcggcg gcctggggct gtcggtgttc gcggcggtgt tcgcgctggc gtcggcggcg
    13921 gccggggtcg gcatcggctg gctcaccgcg ctgtcgggtt cgaagttgat catcaactgg
    13981 ttgtcgctgc cgaccatcct ggcgtacatg gtgagctggg tgacgccgct acgggtcgac
    14041 ggggccggat cgtcggtgct gatcgcgacc cgcgccatct gcgcgctcgc gctcggggtg
    14101 atcctggtgt ggacctggtg gcggttcaag cgcaccgagc gcgaggcggt gctgggcatc
    14161 ctcatcgcgt tcgtggcgat cgtgatcctc tcccccgccg cgctgccctg gtactactcc
    14221 tggccgctgg cgctggccgc cggattcgcg ctctccacac cgactttgat gctgctggtg
    14281 ggcctgtgca cctggctcat gctggtattc gagccgggcg gggcgatcgg cctgtacaac
    14341 ttctggcacg tcgccgcggc caccttcgcc gcggtggtgg cggcgctgtc gctgcgcacg
    14401 gtggacccgt tgcgactacg cgcggacacc ggcaaagcca ggccgtgacc gccgtcgagc
    14461 aggtcgtcgc cgggacggcg gccgatcccg acgcggaact cgcggccgcc taccggcact
    14521 gccgttcgat cgctgccgcg cacgggcgta cctacttcct ggcgacccgg ctgctggcgc
    14581 cggcgcagcg gcccgcggtg cacgcgctgt acgcgttcgc gcgcaccgtg gacgatctcg
    14641 tggactacga atccttcgat gccgcagggc aggtggatcg gatcgagaag cggctgcggg
    14701 agcggctcgc gcacccgctg ccgccggatc cgcaggatcc ggtgctgtcc gccgtcgcgg
    14761 ccaccatcgc ccggtatcgc attgcgcccg accatttctg gacgttcctg gacgccatgc
    14821 ggatggatat ccccggcacg ccgctgttcc gcagccgcta tgccacgatg gccgaactgc
    14881 gcggctacat gcgcggatcc gcggccgcga tcgggttgca gctgcttccg atcctgggca
    14941 cggtcggccc gcgggccgcg gccgaaccgg cggccgccgc gctgggcgag gcgttccagc
    15001 tcaccaactt cctgcgcgat atcggcgagg acctcgaccg cggccggatc tatctgcccg
    15061 cgcgcgagct cgccgccttc ggcgtcgacg acgacctgct cgcgcactgc cgctggaccg
    15121 gtcgcaccga tatccggctg cggcgcgccc tggcccacct gatcgccacc acccgggcgc
    15181 tgtaccgggt ggccgagccg ggcatcgagc tgctgcaacc gcgggtgcgg cccgcgatcc
    15241 gcaccgcggc ggtcctctac gccgaaatcc tcgccgagat cgaggaatcc ggctacgcgg
    15301 tattcgaccg ccgcgcggtg gtgccgcggc gtcggcggct gtgggtggcg gccaccagct
    15361 acgccgctgc cggtgtgcgg gcggtcggcg cgaaccggtc ggacggtatg cctcgagtgt
    15421 gatcgtcgtc cactggacgc ccggggttac cacaggcccg ctcgaggtca ctatcctgat
    15481 ctggtgaact ggaccgtcga cgtaccgatc gaccgcttgc cggaattgcc tccactgccc
    15541 gccgagctgc gtcgccgact cgacgacgcc ctgtcccgcc ccgcgctaca gcagccgtcg
    15601 tgggatcggg accaggccgc gaagatgcgc accgtcctcg agagcgtgcc acccatctgc
    15661 gtgcccgccg aggtcgagga gctgcgcacg ctgctcgccg aggtggcccg cggcgaggcg
    15721 ttcctcatcc agggcggcga ctgcgccgag accttcgccg acaacaccga accacacatc
    15781 cgcggcaata tccgcaccct gctgcagatg gcggtcgtgc tcacctacgg cgcgagcctg
    15841 ccggtggtga aggtggcccg catcgccggg cagtacgcca aaccccgctc cgccgacacc
    15901 gactcgctcg gcctcaagtc ctaccgcggc gacatggtca actcgctggt cgccgaagcc
    15961 gcgctgcgcg aacacgatcc gtcgcggctg gtgcgcgcct acgccaacgc cagcgccgcg
    16021 atgaacctgg tacgcgccct caccggcgcg ggcatggccg acctgcacaa ggtccacgac
    16081 tggaaccgcg acttcgtcgc ccagtccccc gcgggcgccc gctacgagca gatggccgag
    16141 gagatcgacc gcgccctcgc gttcatgaac gcctgccgcg tccaggaccc cagcctgcag
    16201 gccgccaaga tctacgccag ccacgaggcg ctggtgctcg actacgagcg ggccatgctg
    16261 cggctggccg agaactccgc gggcgacccg gtgctctacg acctgtcggc gcacttcctg
    16321 tggatcggcg agcgcacccg ccaactcgac ggcgcccaca tcgccctcgc cgaactactc
    16381 gccaacccga tcggcctcaa gatcggcccg agcaccagcc ccgaactggc ggtggaatac
    16441 gtcgaacggc tcgacccgaa caacgagccc ggccgcctga cactggtggc gcgcatgggc
    16501 aacggcaagg tccgcgacgt gctccccccg atcatcgaaa aggtccaggc cacagggcat
    16561 caggtgatct ggcagtgcga ccccatgcac ggcaacaccc acgaatcctc caccggctac
    16621 aagacccgcc acttcgaccg catcgtcgac gaggtacagg gcttcttcga ggtacaccgc
    16681 gccctcggca cccaccccgg cggcctgcac atcgaactca ccggcgaaaa cgtcaccgaa
    16741 tgcctcggcg gcgcacagga catctccgac ctcgacctcg aggaccgcta cgaaaccgcc
    16801 tgcgacccac gcctgaacac ccaacaatcg ctggagctgg cgttcctcgt cgccgagatg
    16861 ctgcggtgac ggaggcgtcg acatgcacgt cgtcttccgc tcgccggata cccggcacgg
    16921 ggaaccggcg gaccgcacca tcctgcggtt gctgcgcgat cgcgatcgcg acggcgtgcc
    16981 ctcggaggtg gtgctgcgcg acggcagccg gttactgatc ttcaacatct cctggggcta
    17041 cgatcccgcc gcggtgtcgg cccaggtcac cacgaatatc agcccggcca tcggcggggt
    17101 gtcggtggac gtgttcagca cggccgcggt ggtcgccgtc aacgatccgg agaccgggtc
    17161 gccgctgctc gccgtcgcgt gagtggcagg tgtcacaagg atgaaaagtt aactactagg
    17221 ttgctagagc cgacggaatt gcactaggtt tctcagtgtc cgctcgcggc agcggcggtt
    17281 cagaggcggt atttgcactg ggaggcccga tgtacggcat gacggtagcc gaggaattgc
    17341 gatccatgtc cggcggcggc ccgaccgccc tggcgcagca cgaatcggtc gtgaacggca
    17401 tcccggtctc ggtcctgatc gaacgccccg aggtggatcg cgcgggcagg gcctggcgct
    17461 gccgggtgcg cgtggtgcgc ggcaccgggc gcatcgaaca gtcgcaggtg gtcggcacca
    17521 gcgcccacga ggtgctggag caggcgctgg aactcgcggc gacgcgcctc gggatcagcg
    17581 aatccgaact gctcagcggg gccagcatgg gcctggacac ggactcggat cgctaagtcc
    17641 cccagccggt ttcagatcgg caggaccgtg agcgtcaccg tggcgccggg cgcgacgctg
    17701 gcgcccgcga acggcgcctg gatgcgcacc atgccgcgat cgctggcgaa gacctggttc
    17761 agcaccaccc gcagcccgag ctgctccagc tgggtgcggg ccgcgacggc cgtcatcccg
    17821 gtcacgtcgg gcacctgaac ggcattggag acgatcagcg tgaccgcgtc gccggacagc
    17881 gcgcgggtgc ccgcgccggg atcggtgccg atcacctggc cggacttgat ccgggggtcg
    17941 aagtcgttcc tggtgtcgcg caccgtgatt cccgcgctct gcagcatggc gcgcgcctcg
    18001 tcgacggtcc ggccgcgcac ctcgggcagc tgcaccggct gggatccctt gctgcggtag
    18061 atcttcaccg ccgcgccggt gggcagcacc gtgcccggct ccggctccaa ctggaacacc
    18121 gcgcctttcg gcgcggtgct gggtcgctcc cccgcgtcca ccggttgcag accggcatcg
    18181 cggatgagct gctcgaccgt cttcagatcc tgtccctcct gaaacttcgg cacctgcggt
    18241 ttcccgctgg agaccagcac cgccaccgag gagcccttca ccacccgggt gcccgcggac
    18301 gggtcggtgc ccagcacgcc gcccaccggc acggtgtcgg atgccttgcc gcgcatggtg
    18361 gtcgagaatc cggcgtcgtg cagggcggcg gtggcgcgct gggaatccat gcccgcgatg
    18421 gccggtaccg ccgaatagcg ctccacgccc agccaccagc cgccgatgcc gagcagcaac
    18481 gccagggcga tgaccaggcc cacccagaac agcacccggc cccggcccgt gtgcccgcgg
    18541 tcgggtcgat acggatcgtg gtagggctcc ggcggctccg gggcgtgggc gacccggccg
    18601 gtgtacccgt cggattcggc gcgcggctgg gtggcggtca tgacccgggt gcgctgcggc
    18661 gcgggcgcgt cggccgccag ccgggtggtg gcgtcggccg ggatccggcg gggctcggcc
    18721 cgctcgcgcg gcggggcggg cggcacgggc gggacccggt actgggcgga caggtgttcg
    18781 gccgattcgc gcggggcggg cacccggtag tcgggcagcc gtaattcggc ggcgatgcgg
    18841 cgtagctcga ccgccatctc ggtggcgtcg gcgaagcggt gcgcgggctc gcgcgcggtg
    18901 gcgcgcgcga tcagctcgtc gaactccggc ggcaccccgg cgatgaaccg gctcgggctc
    18961 ggcacgtcct tctccacccg ctgataggcg atgcccagcg aggtgtcccc ggtgaacggc
    19021 gttcgaccgg tgagcatttc gaagatcagg atgccgaagg agtagacgtc gctgcgggcg
    19081 tcggcgctgc cggcggtgac ctgttcgggc gacagatagt gcgcggtgcc caggatcacg
    19141 ctcgcggagg tgagattcga cccggccacg gcgcgcacca ggccgaagtc ggccatcttg
    19201 acctcgccgg aatcggagat cagcacgttc tccggtttca cgtcgcggtg caccagcccg
    19261 gccgcgtgcg ccacgccgat cgccgccagc gcgggttcgg cgaccgcacg caccgcgtgc
    19321 ggcggcatgg gcccgcgctc gcgcagcagc tcgcgcagcg tgccgccctc gaccagttcc
    19381 atgatgagga acgggtactc gccgtcgatg ccctggtcgt acaccgcgac cagggccggg
    19441 tgtttgagtt tggcgaccga gcgcgcctcg aactcgaagc gggtcagaaa ttgcgggtcc
    19501 ccggcgaatt tcgggtccat caccttgatc gcgaccggtc gatcgaggcg ggtgtccacc
    19561 ccccggaaca ccatcgacat cccaccgcgc gcaatcggtg catcgatgcg gtagcgcccg
    19621 tcgagcatct ggccgatcaa ctggtgtcct ccgactttca caaagctctc gcctctcgct
    19681 tcggctgcga caaggggaag ccgcccccgt gacggctccc ccgatggtat aggcggaaag
    19741 gacccgggtg tctcacgact tgcctggcgc gacggactac cgttgtccgg gtgagtgcat
    19801 ttccatgcag tgacgacgtc ctgtcggagt cggtaaccct actcccccta ccggatgttg
    19861 ccgaccagct cggcatcgcg gtgaccaggg tgcatcagat gctgcgcgac catcagctca
    19921 tcgcggtgcg ccgcgagggc atcaccggga ttcccaagga tttcttcgat cccgacgggg
    19981 ctgtcgtcaa gcccctaccc ggcctgatca ctgtgatgcg cgacgcaaaa tacacgaacg
    20041 aggaaattct cgagtggatc tacaccgtcg acgagaccct gccgggtcgc ccgatcgacg
    20101 ccctgcacgg tccactcgcc cgggaggtgg tgcggcgcgc ggcggccgaa cccttctgat
    20161 gacatagctg ttcggtgggc tcccgtggat gcggcctggg tcgcacccac gggagccttc
    20221 gtgcgttgct ccccggtccg gatcggtcgc ccgcgggagc cggaaaggca ttcgaatcat
    20281 tgagatattt ctacgactgc gaattcgtcg aggacggaat cacgatcgac ctgatttcga
    20341 tcggcgtggt ctgtgaggac gggcgcgagt actacgcggt atcgacggag ttcgaccccg
    20401 atcgggccgg gccctgggtg cggcgccacg tgctgccgaa gctgcccgag cccagctcgc
    20461 cgctgtggcg cagccgggaa cggattcgcg aggacctcta cgccttcctg gtgccgcgcc
    20521 cgaccgtcga gccgcagctg tgggcgtggg tgagcgccta cgaccacgtc gccctgtgcc
    20581 aactgtgggg ctcgatggtg gacctgccca ccgccctacc ccgctacacc aacgagctgc
    20641 gccaacactg ggacatggcc gggatcagct ggccatggtt tccgggacgc ggtcggcgtc
    20701 ggggtcgtgg tgatcgtgtc gcgccgggcc atggtgatcg ggtcatgctg gggttatttc
    20761 ccttttcttg gttccggcgt gcttttggcc gggatcagct ggccatggtt tccgggacgc
    20821 ggtcggcgtc ggggcggggg ccggagggga cgcccttctt gaggctggcg gcgtagacgt
    20881 cgacgtactc gcggcccgac atccgcatga gctcgtacat gatctcgtcg gtgacggcgc
    20941 gttcgacgaa gcggttgccg cccatgccct cgtagcgcga gaagtcgatg ggcgcaccga
    21001 atttcacggt gacccggcgg cggcgccagg tgaacgggcc gggcgggcac acctcgtcgg
    21061 tgccgatcaa cgccaccggg atgaccggga cgccggtctc cagggccagg cgcgccacgc
    21121 cggtcttgcc cttgtacagg cgaccgtcgg gcgaacgggt gccctcgggg tacaggccga
    21181 ccaaccggcc ctgctcgagc agtcggcgcg cggtgttcag cgcgtcgacg gcggcgtcgg
    21241 cgccggtgcg gtcgatgggg tactggccgg tgccggagaa gaagaacttc tgcaaccggc
    21301 ccttgaggcc cggggtggtg aagtattcgg ccttggccag gtaggtgatt cggcgcgggc
    21361 tcatcagggg ggtgaacagc cagtcggtga acgacaggtg gttgcccgcg aggatggctg
    21421 gtccgtcggc cgggatatgt tccacgccct cggccttggg ccggttgtac aggtgcatga
    21481 acggccccgg aaacacgtac ttcagcagcc agtagaacat tgcgtccttt ccccagtgag
    21541 gcttacggac cggccgccac cgcggcgcca ccatccgttg ccgactctac cgtcggtcac
    21601 gagttgtgac caagcccgca cagccgattt cacaccgggt cgaaccacac cgccgaccgg
    21661 gccgtcagcg gcgggcgccc gccttgccgt cggcggccgg ggagcggccc gccgcggtcg
    21721 acgagcggcg gcccgcaccc gattttccgg aggtcttcgc ggtggatttc gcaccggggg
    21781 ttggcttctc ggcgggcgcg ccgatgcgct cggacaccag cgccgcccgc gccagttccg
    21841 cggccccgac catgcccgcc gcctcgccca gctgggtggt ccggatgcgg gccagcgggc
    21901 ggtgccgagc gccggtgatc gcggcggcgt agtgctcgcg ggcgtcgtcg aggaacatcg
    21961 gcgcggacga gctcaccccg cccgcgatca cgatcagatc cggatcgaag atgtcgctga
    22021 caaaggccag gccgagaccg agccagcgtg cgaattccgc catcacccgc agcgcgaccg
    22081 gatcgccgtc ctgcgcggcg cccgccaccc ggcggccggt cagcgagccc ggatcgcggg
    22141 cggcgtcgcg ggccaggatg gtcgagctca tcgggtcggt ggcgagcatc tcgagcgcgg
    22201 tgtccaccag agccgttccg ctgcaatacc gttcccagca gccgcgcttg ccgcacgggc
    22261 aggcccggcc gtgcggcacc acctgcagat ggccgagttc cggtgcgacg ccgaagcttc
    22321 cgcgatacaa ccggccgccg accagcagcg ccgcgccgat gccggtgccg atggcgacca
    22381 gcacgccgtt gtgcgcgccc gccgccgcgc cgaatcggta ttccgcccac atcgcggcat
    22441 tggcgtcgtg ctcgaggatg accggcaggc cgagccggtc ggtgagccgc cgcgcgaccg
    22501 gcgtgtcctc ccacggcaga tgcggcgcga accgcaccga cgaccgggtc tcgtcgacaa
    22561 atccggccac cgcgaggccg accgcgccga tcgggtgccg ggcgcacagc tcgcgcaccg
    22621 cacgctcgag gccgtcctcg agcgcctgct ccgaatgcgg ggtcggggcc tgcaccgtgt
    22681 ccagcacctc gcccgcgccg tcgaccaccg aggcgcgaat gttggtgccg ccgacatcga
    22741 tgccgaccgt cagcggggcc tcccgcccga tgcgtgtcgt catgccttga tctgcaccgg
    22801 aatcgggacg taccgggact tgccgcggtc gcggcggggt tgggtggttg cggacatccg
    22861 gcccatcgtg ccatgtttcg tgccgggcgc gtcgcccgca ttgcgggaat cactcgtctc
    22921 gtccggcggg aatatcggtt ccaccggcac cccggccagg gcctcgcgca gcaccgtcac
    22981 gatcgccgtg ccgtgctcgg ccagcgccgc caccacgtcg tgatgttggc cgcggaccag
    23041 cgcggccgcc gcgcacaccg ggcaccagct gcagctgtcc cattcggtgc ggccgtcggc
    23101 ggacgcctgg cgcagcaccg gttccacgcg ctcgaggatc gtctcggcca gcaggcgcag
    23161 ttcctcggcg aattcggcga agttgtcccc gtgcgccgcc tcgtcgtgat cggccgcgtc
    23221 ggtgcgtgct tcgccgcccg agtcgccggg ggtctcgtcg gtcgcggtgt cttccggggc
    23281 agtgcggcgg ccgacgggtt cgccccggac ccactcgcgc ccgctgcggc cgcccgcgcc
    23341 gtcgctcatt gcggccagac ctcggcatcg gggcggaacc gcacgaccag gtcgccgtcg
    23401 tcgagttcgg cgccgtcgac cgtgcagcgc cgcagcaccg gcgccaggcg caggcgtcgc
    23461 cggaccccgt ccgctcccac gatcaaatcg tcctccactc gtcccagtcg cagcgtcgcc
    23521 gggtcgacga cgggcaaccg cagccgcagg gtgaacaccg agtccaggcc cgaccccgag
    23581 gtcagccgca cctgcggcgc accggatcgg gcgaagtcgg cattcgctcc gcccagcata
    23641 gggtctggcg gggacacggc catggcggac agcgaggcga ccccgaccgg ttccgcgccg
    23701 ctgtgctcga cgatcgccac cggcacgtcc ggcatgcggc ggcgcagttc ggccagcacc
    23761 tgctgctgtt cggcgtggcg gtcgagatac cagcgcacgg ccggatgggc ggcggggtcc
    23821 gcgggcggca ccggcggcag caccttgttc accaccacct cgtccagccg caggcccagc
    23881 agcgcggccg ccgaccgcac ccgcgccgac tcggccagcg ccacccgttc gggcacggtg
    23941 atcagccggg cgccggtgcg ctcgcggtcg gccagcaggt cgcgggcctc ggtgaccgcg
    24001 gcggcgatgc gctccacggt ggtcgcgagc accgcccgcc gcagatcggt gccggtggcg
    24061 tcgagcatgc gggcgtgggc gggccagatc cgctccaggt agccgagcag cgtgtcgggg
    24121 gcggtgacga tgcgcaacat gtccgccgag ggcgggcagt ccacgacgat cacatcccag
    24181 tcctcgtccc ccgcgaactg ggcgatctcg gtgagcatga gcagctcctg cacgccgggc
    24241 aggccggtca gctcggccgg gtccagggcg gcggggtcga tgccgtgctc gtggcccgcg
    24301 ccggacagca tccgcgccgc gtcgcggaac cgatcctcca gcagcgcaag ggaatcgatc
    24361 tcgatgacgt ccaggccggg ccggaccgtc cgcacgccgg tcaccgcgcc gggatcgtgc
    24421 gggaaccgga agccgagcgc gtcgccgagg gaatgggcct ggtccagcga cgccaccagc
    24481 acccgcgcgc cgccgcgggt gtgcgcgatc gcggtggcgc acgccagcgt cgtcttgccg
    24541 accccgccct tgccgacgaa cagctccagg cgcgtggtgg tggtcagccc tcgacccgtt
    24601 tcttgagttc cttgagcgcg gtgtcggtga tgaccttctc ggccttgcgc ttgaacatgc
    24661 cgatcatcgg gatggtcagg tcgacggtca gctcgtagac cacctgggtg gtgccgtcgg
    24721 gctggtcgat cagctcgtag cggccgtcct gcgccttctg cagttcgccc tcgatcagct
    24781 gccagctcac cgccttgccg tcgggccgcc aggtgtagga cagcacgtag gtgtccttga
    24841 ccaccccggc gtcgagcacg aagcgcgcgg tgtgcgcccg gccgtcgccg aacttgtcga
    24901 gaacctccac cgaacgcgcc gccgacaccc actccggata cgactccaga tcggcgatga
    24961 cggccatcac ccgatccgac ggggcgtcga tggtgatcga cctctgggtc cggtcggcca
    25021 tgactgacag cgtttccttt ccggattacg gtgcgggaga gcgatattca ggacgcgacg
    25081 ggaaccggca cggccggtgc gaccccggcc ggacgacccg cctcgagccg cgccttcacc
    25141 tcgaacgaca tgaccttccc ggccgcccgg cgggcacggt tggcggcgag caggccctgc
    25201 ggcgacaacc gggcggcgcg cggttcggcg tgcaggaagt agtgcaggat caccccgtcc
    25261 aggcagggtt cgagccagac ctccatggtg ccggtcaggc cgccgctcac ggtccagcga
    25321 atgcccttgt cggcccggtc ctctcggacc tcgagcgtga gatcgggcca ccagcggcgc
    25381 caccgcgcgc gatcggccag cacctcggcg accgcgctgc cg
//
