LOCUS       NZ_KV411304            21266 bp    DNA     linear   CON 12-FEB-2024
DEFINITION  Nocardia terpenica strain IFM 0406 scaffold2, whole genome shotgun
            sequence.
ACCESSION   NZ_KV411304
VERSION     NZ_KV411304.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardia terpenica
  ORGANISM  Nocardia terpenica
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 4638951)
  AUTHORS   Buchmann,A., Eitel,M., Koch,P., Schwarz,P.N., Stegmann,E.,
            Wohlleben,W., Wolanski,M., Krawiec,M., Zakrzewska-Czerwinska,J.,
            Mendez,C., Botas,A., Moris,F., Cortes,J. and Gross,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-APR-2016) Pharmaceutical Biology, University of
            Tuebingen, Auf der Morgenstelle 8, Tuebingen 72076, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 30-JUL-2014
            Assembly Method                   :: CLC NGS Cell v. 7.0.4
            Genome Coverage                   :: 118.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/12/2024 01:56:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,832
            CDSs (total)                      :: 8,760
            Genes (coding)                    :: 8,562
            CDSs (with protein)               :: 8,562
            Genes (RNA)                       :: 72
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 40 of 198
            Pseudo Genes (incomplete)         :: 174 of 198
            Pseudo Genes (internal stop)      :: 9 of 198
            Pseudo Genes (multiple problems)  :: 23 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:51:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2787229
            Orig. end                         :: 2808495
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KV411304.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21266
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="20"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21266
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21266
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11266](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11266
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            895..1992
                     /locus_tag="AWN90_RS33645"
                     /old_locus_tag="AWN90_33670"
     CDS             895..1992
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019929639.1"
                     /locus_tag="AWN90_RS33645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33670"
                     /product="glycosyltransferase"
                     /protein_id="WP_082871585.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.9e-20,
                     bitscore: 69.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPIPSARSHHRIPVAHARAGGHPGRAHAVSVVVPVYRGEDTIAGL
                     VAELHELSRPTTTPGGTAFVVDEIVLVHDHGPDRSDLVLQRLDREYEQVRVVWLSRNFG
                     QDAATIAGMAAARGEWIVTMDEDGQHDPGFIGTFIDTALSQRADLVYSKPTNTRPHGVL
                     RNLTSRGSKVVLATLFAFPDSTRFESYRLIRGDIGRQLAEVASNGVYLDVALTWVVDNT
                     AQAPVLLRAEGRENSGYNYRRLFSLFWKMVLCSGTRGLRVVSMLGVTLAASGLVYAAII
                     VWQKMFGHGDNPEGWASTIVVLLLVSGAILFSLGLIAEYLGVALHILVGKPLYLTVDSP
                     TPRPDAETPALTTSAAIGGNNPGEY"
     gene            1982..3118
                     /gene="rffA"
                     /gene_synonym="fcnA; wecE"
                     /locus_tag="AWN90_RS33650"
                     /old_locus_tag="AWN90_33675"
     CDS             1982..3118
                     /EC_number="2.6.1.59"
                     /GO_function="GO:0019180 -
                     dTDP-4-amino-4,6-dideoxygalactose transaminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009246 - enterobacterial common antigen
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="rffA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="fcnA; wecE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019929640.1"
                     /locus_tag="AWN90_RS33650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33675"
                     /product="dTDP-4-amino-4,6-dideoxygalactose transaminase"
                     /protein_id="WP_067591132.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 7.6e-93,
                     bitscore: 309.7, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 1.1e-08, bitscore:
                     32.4, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.3e-08, bitscore:
                     31.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTDRIIFSRPHRAAGELANLEAVLASDHSHGDGPFTAAATAKLK
                     AITGAPYALLTTSCTHALEMAGLLLELGPDDEVIVPSFAFTSTATAMALRGATCVFVDI
                     DERGNIDPESVAAAITPRTKAIALIHYGGVAAEMDRLQEIADAHGIAIVEDTAHALGAT
                     WRGRPLGSIGTAGALSFHDTKNIHCGEGGALLLNDEILMARAEIIREKGTDRARFLRGA
                     VDKYSWQDIGSSYLPSELNAAVLDAQLAEFDTIQAGRFRVWNAYAAGLPDWARRNDIRL
                     MQVPPDREHTAHLYYLRTPTEDRRDDLIAHLRERGISAPFHYVPLDSSPAGLKLGRTPH
                     PCVRTAEFSGTLVRLPLWPGLSDAQVQRVLEAVTAFEV"
     gene            complement(3129..4613)
                     /locus_tag="AWN90_RS33655"
                     /old_locus_tag="AWN90_33680"
     CDS             complement(3129..4613)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (80-258). E-value:
                     7.9e-17. Score: 53.6. Matches aSDomain:
                     nrpspksdomains_AWN90_RS33655_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012770.4"
                     /locus_tag="AWN90_RS33655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33680"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_067591135.1"
                     /sec_met_domain="PF00561 (E-value: 5.7e-25, bitscore: 86.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSILSVALLAAVCAACGSGSKSTTPAAPPIAWKACPPAYGTLVQ
                     CADIEVPLDWDKPDGDKITVGIDRLPASDPSHRIGALVVNPGGPGGVGTELVAGESTHP
                     GALFPPELRARFDLVGLDPRGIGTSRPAVRCDPDLQNKLTDIFPADEAAYRAMVAANRA
                     YGDSCRTRTGPLLDHVDTVAVARDLDVIRQRLDAGPLNYLGLSYGTEIGFEYARLFPTG
                     SRALALDGALVHSLPPSSMHVYEAEAFEDSLHRFADWCRGATDCALGTDDAVAVVHDLA
                     TRARQAPLPAPGCAASHQCAPQVGAGDLLSQIQDGLLFKPARSASGTGWAGLATHLDQA
                     RPGDASGLSPQAATETGNAGQAVGCAEFRADYDTYAAFKTEQILGETIAPDTLGAGQSY
                     GYLAQCQGWPGAFSNPPHTALAKPTITPLLINATHDPSTFYGWAQLLSTEIPNAVLLTR
                     NGDGHTSFLIPGQTRDAITRYLIDGTLPAPGTVLPD"
     aSDomain        complement(3840..4373)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AWN90_RS33655_Abhydrolase_1.1"
                     /evalue="7.90E-17"
                     /label="AWN90_RS33655_Abhydrolase_1.1"
                     /locus_tag="AWN90_RS33655"
                     /protein_end="258"
                     /protein_start="80"
                     /score="53.6"
                     /tool="antismash"
                     /translation="ALVVNPGGPGGVGTELVAGESTHPGALFPPELRARFDLVGLDPRG
                     IGTSRPAVRCDPDLQNKLTDIFPADEAAYRAMVAANRAYGDSCRTRTGPLLDHVDTVAV
                     ARDLDVIRQRLDAGPLNYLGLSYGTEIGFEYARLFPTGSRALALDGALVHSLPPSSMHV
                     YEAEAFEDSLHRFAD"
     gene            complement(4687..5205)
                     /locus_tag="AWN90_RS33660"
                     /old_locus_tag="AWN90_33685"
     CDS             complement(4687..5205)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014982610.1"
                     /locus_tag="AWN90_RS33660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33685"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_067591138.1"
                     /transl_table=11
                     /translation="MIRPAREADLPGLRELERAAGKPFADIGMSSVAEDEPPSIEQLRA
                     FADDGRAWVIADATDTPIAYLILDVVDGNAHIDQVSVHPDHAGRRLGRDLIEYAAEWAV
                     ARGIAALTLTTFTEVPWNGPYYERLGFHRLPVAQETPGLRAARAAEAAHGLDAWPRACM
                     RRELPRTPE"
     gene            complement(5202..8159)
                     /locus_tag="AWN90_RS33665"
                     /old_locus_tag="AWN90_33690"
     CDS             complement(5202..8159)
                     /NRPS_PKS="Domain: AMP-binding (447-857). E-value: 7.5e-42.
                     Score: 135.2. Matches aSDomain:
                     nrpspksdomains_AWN90_RS33665_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748602.1"
                     /locus_tag="AWN90_RS33665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33690"
                     /product="AMP-binding protein"
                     /protein_id="WP_067591142.1"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-29, bitscore:
                     100.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFDTRTVVGSVQRLLATAQNGLEVIRFGGLTHDVESSPYEVTER
                     KRMYRLRHYFPDDTTPGRPVALFVPPLMVSADIYDVNAEGGAVGILQRAGIDCWVIDFG
                     SPATEEGGWKRDLADHVLALSSAIDTVTELTGRGVHLMGYSQGGMFAYQTTAYRFGKGV
                     ASIVTFGSPVDIVAGLPFGLPQGLVSDVADFVADHVLNRLPITDSMVRIGFQMLDPVKT
                     AKARVDFLRQLHDREALLPKERQRRFLQQDGFVGYAGPAAADLLKQFVAHNRMMLGGFV
                     IRDQPVSLAELRCPILAFVGEVDDIGQPVAVRGIVRAAPNADVYEASLMAGHFGLVAGS
                     TATTRTWPLVRDWIRWIGGGGERPEGIEPMDEPADAARRRTAATRVVHTAAALAEAGAG
                     IGQALTDIAGSTLRGSVELTGEAARALPRLTRLGMIQSHTRISLGRLLDEQARRAPLRE
                     CFLFDDRVHTNAAMNVRIDNVVRGLVSEGVRPAARVGVLMETRPSALVAVAALSRIGAV
                     AVLLAPGGELQRAMEITGARTLVADPENLRDAAATGARVLVLGGGDARGLDLPHDGEVV
                     DLEQIDPEQVRLPGWYRPNPGLARELAFVLVTGTGDKLDIKYITNHRWALSAFGTATAA
                     DLDRRDTVYCLAPLHHSSGLLVSLGGAVAGGSRIALARSLDPARFAEEVHRYGVTVVTY
                     TWTMMRDILDADSFPDGRPHPIRLFIGSGMPAGLWRRTTERFAPARVLEFYASIEGDVV
                     LANVSGSKTGCKGRPVPGTARVELIAYDSVTGEIRTDAQGFARRAADNEVGLLIGKASE
                     TVDISLGGLRGVFTPGDAWMPTENLFRRDGDGDYWLMDRRDTVIQTPHGPVYTQPIVDA
                     LNDITAVDLEVAFGLPAGGTTLAVAAVSLRRGYRLEPKDVTEGLRALDPAQRPDLVYVV
                     DEIPRSSTYRPSTRAVQAAVRLQPGEKTWYFDRTTETYEPLTPEVLDQLLRRTTR"
     aSDomain        complement(5589..6818)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AWN90_RS33665_AMP-binding.1"
                     /evalue="7.50E-42"
                     /label="AWN90_RS33665_AMP-binding.1"
                     /locus_tag="AWN90_RS33665"
                     /protein_end="857"
                     /protein_start="447"
                     /score="135.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DEQARRAPLRECFLFDDRVHTNAAMNVRIDNVVRGLVSEGVRPAA
                     RVGVLMETRPSALVAVAALSRIGAVAVLLAPGGELQRAMEITGARTLVADPENLRDAAA
                     TGARVLVLGGGDARGLDLPHDGEVVDLEQIDPEQVRLPGWYRPNPGLARELAFVLVTGT
                     GDKLDIKYITNHRWALSAFGTATAADLDRRDTVYCLAPLHHSSGLLVSLGGAVAGGSRI
                     ALARSLDPARFAEEVHRYGVTVVTYTWTMMRDILDADSFPDGRPHPIRLFIGSGMPAGL
                     WRRTTERFAPARVLEFYASIEGDVVLANVSGSKTGCKGRPVPGTARVELIAYDSVTGEI
                     RTDAQGFARRAADNEVGLLIGKASETVDISLGGLRGVFTPGDAWMPTENLFRRDGDGDY
                     WLMDRRDTVIQ"
     CDS_motif       complement(7701..7745)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AWN90_RS33665_0001"
                     /evalue="9.40E-04"
                     /label="NRPS-te1"
                     /locus_tag="AWN90_RS33665"
                     /protein_end="153"
                     /protein_start="138"
                     /score="11.8"
                     /tool="antismash"
                     /translation="VHLMGYSQGGMFAYQ"
     gene            8580..9986
                     /locus_tag="AWN90_RS33670"
                     /old_locus_tag="AWN90_33695"
     CDS             8580..9986
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014983543.1"
                     /locus_tag="AWN90_RS33670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33695"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_067591145.1"
                     /transl_table=11
                     /translation="MTIDLPPQIENHVRKSLSTGAARNLAHTTKSEPQMQGITSRWLTR
                     RLPWTEVRGGVYRVNRRLTYTLGNGEIEFDVDGPQARVIPVELRELSQLRDMEDEDILG
                     ALAGSFEQRDLDPGEIVAEFGNPMDQLVLVVHGKLSKLGTGEYGETLGLGVLAGGMHAG
                     DRMLVDRDAIWPFTVRTLTPTTLLVLSRAGLERVLDQAPALREHLDRVAAGPARPQTKH
                     GEAEIDIASGHSGEPLIQGTFVDYEANPREYELSLGQSVLRIHTRVADLFNEPHNQIEQ
                     QLRLTIEALYERREHDLVNNTDFGLLHNCDLKQRIHTETGAPTPDDMDELLSMRRSTKL
                     FLAHPKAIAAFGRECSKRGLYPDPVEVDGSRVPAWRGVPIFPCSKIPVSDTQTTSILAM
                     RTGEQDQGVIGLHQTGIPDEYEPSLNVRFKGIDDQSIISYLISCYYSAAVLVPDALGIL
                     DNVLVARHSD"
     misc_feature    8604..8619
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.22"
                     /tool="antismash"
     gene            10001..11266
                     /locus_tag="AWN90_RS33675"
                     /old_locus_tag="AWN90_33700"
     CDS             10001..11266
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019929645.1"
                     /locus_tag="AWN90_RS33675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33700"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_067591148.1"
                     /sec_met_domain="T1TS (E-value: 8.2e-58, bitscore: 194.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVLSRVAAPPATDDVADVIAALLTNLEGAPAPELSLSTEAEAAV
                     PRFDSNLLSGMVARAVPRRLLGPVGLGAASLLVEPPGGARESPAAATGSAIPPLYCPPP
                     VRDDPALAEAVNAGIISWAQAIGLYEGRLDELHRADFGRLIMLAHPDCDDPDRLLAAAK
                     CAVSEWSVDDYYCEEDADDRAPDGSPSSAEAELGPRLELAMAAIDPVHLPDRYQVQLER
                     ALDADPILRAFRTSFDHLAHYATPAQLARLRTEIGGWFIALGAEAGWRAAGRMPPVWEY
                     LTNRQPHSFLPCMAPIDAVGGYELGAADYTDPAVRRVVTTAALAAQMVNDLYSMAREDL
                     SGGREFNLPTVLAAEENCSRREAVGHTAAVHDELVHRFEREATVLAATASPQLRRFLAG
                     LWAWMGGNRAWHADSRRYRETE"
     misc_feature    complement(10047..10061)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    10196..10198
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11295..12167
                     /locus_tag="AWN90_RS33680"
                     /old_locus_tag="AWN90_33705"
     CDS             11295..12167
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014983542.1"
                     /locus_tag="AWN90_RS33680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33705"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_067591151.1"
                     /transl_table=11
                     /translation="MTTLDSPTDSVLRTSYQRSVAAYWNDNPNDDRVNTKLGEVDGLYH
                     HHYGIGEPDLSVLEGPADTREDRIVRELHRLETAQADLLLDHLGPVTAGDRLLDAGSGR
                     GGTSFMANERFGCQVDGVTISEYQAGFANDQARERGVAERVRFHFRNMLDTGFDSGSRR
                     GIWTNETTMYVDLFDLFAEFARVLAPGGRYVCITGCSNDVTGGRSAAVSWIDAHYGCMI
                     HPRGEYFRALAAHNLVPIAVVDLTPATIPYWELRTHSELATGVEKPFLSSYRDGSFQYL
                     LIAADKVGS"
     gene            12164..12757
                     /gene="idi"
                     /locus_tag="AWN90_RS33685"
                     /old_locus_tag="AWN90_33710"
     CDS             12164..12757
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014983541.1"
                     /locus_tag="AWN90_RS33685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33710"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_231951754.1"
                     /transl_table=11
                     /translation="MSADCDTPPSGREALLVELVDEQGHPIGSCTVSEAHTAPGHLHRA
                     FSVLLYDDEGRVLLQQRASVKTRFPLRWSNACCGHPAPGQSVAAAAAVRLAEELGVEAD
                     PADLTEVGVYRYRAEDPATGRVESEWDHVLIGRFEGVPPQPDPGEIDGHAWVRPQALTE
                     ALAAAPADYTPWLAGVLAAAEQGRASGLAPIVSD"
     gene            complement(12676..13191)
                     /locus_tag="AWN90_RS33690"
                     /old_locus_tag="AWN90_33715"
     CDS             complement(12676..13191)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003881821.1"
                     /locus_tag="AWN90_RS33690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33715"
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_067591154.1"
                     /transl_table=11
                     /translation="MQLSRFTDLGLRAMMRLAVSRSGDERVTTKLIARQINASEHYVAK
                     AVTKLSDLGLIAAQRGRAGGIVLTERGRSASVGGIVRELEGGSAVVDCHGDQPCPLAGA
                     CRWRHALADAQEAFYQELDKYTLSDLIDRHVIDVLLAPPGDQSLTIGASPLALPCSAAA
                     STPASQGV"
     misc_feature    13219..13234
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.5"
                     /tool="antismash"
     gene            complement(13244..14707)
                     /locus_tag="AWN90_RS33695"
                     /old_locus_tag="AWN90_33720"
     CDS             complement(13244..14707)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019929648.1"
                     /locus_tag="AWN90_RS33695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33720"
                     /product="NCS1 family nucleobase:cation symporter-1"
                     /protein_id="WP_067591157.1"
                     /transl_table=11
                     /translation="MTETIPPATAARATGYDPRLTNADLAPLREQRWGTYNIVAFWMSD
                     VHSVGGYVTAGSLFALGLASWQVLLALVIGIGIVYGLCNLVAAPSQRAGVPYPVVCRSA
                     FGVLGANIPAIIRGLIAVAWYGIQTYLASAALIVVAVKLFPGLARYAVVGDYGFLGLSL
                     LGWGGYLLLWAVQACVFWRGMESIRRFIDFCGPAVYVVMFALCGYLIAKAGWGAIDLNL
                     GRVRYSGVDSIPVMLGAIALVVSYFSGPMLNFGDFSRYARSMRAVRRGNLLGLPVNFLM
                     FSLLVVITAALTVPVYGTLITDPVQTVARIDNTFAIVLGALTFTVATVGINIVANFISP
                     AFDFSNVRPQQIGWRAGGMLAAVGSVLITPWNLYNNPQVIHYTLEVLGAFIGPLFGVLI
                     ADYYLVRGRRIVVDDLFTRSERGSYWYRRGFNPAAIVATVVGAVVAVIPVLATRVPGMY
                     TAAQYSWFIGCGLGLIVHRSLAGRYRVRR"
     misc_feature    complement(14783..14799)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.52"
                     /tool="antismash"
     gene            complement(14841..15365)
                     /locus_tag="AWN90_RS33700"
                     /old_locus_tag="AWN90_33725"
     CDS             complement(14841..15365)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS33700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AWN90_33725"
                     /product="hypothetical protein"
                     /protein_id="WP_156674590.1"
                     /transl_table=11
                     /translation="MTRFGRMAALPVIALLAGAAMSGSGPAAAEPLGRCDGGEFRWTAA
                     DGAITMTPQWLTFTSAGTLRDCAGVVPGITGGTFTGVHTAWSDCMHPADGPITLAITWS
                     DGETSTVAGPWPVAMAQPTTGTLEVTDGLGRGRRVRITVAYDMVTPETVGGCLGAGVRT
                     GTGRILGTMFE"
     gene            15654..16883
                     /gene="ilvA"
                     /locus_tag="AWN90_RS33705"
                     /old_locus_tag="AWN90_33730"
     CDS             15654..16883
                     /EC_number="4.3.1.19"
                     /GO_function="GO:0004794 - L-threonine ammonia-lyase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006549 - isoleucine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ilvA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014983534.1"
                     /locus_tag="AWN90_RS33705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33730"
                     /product="threonine ammonia-lyase"
                     /protein_id="WP_067591163.1"
                     /sec_met_domain="PALP (E-value: 1.2e-82, bitscore: 275.7,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAMELIGPDRLEAAAKLLEPVIRRTPLVASRVLSERTGFEVRLK
                     CENLQRTGSFKPRGAYNRIANLPERDRKRGVVAASAGNHAQGVAWAASSLGIDSTVFMP
                     VGASLPKLVATRSYGATVYQVGETIEQSLGAALEFAERTGATLIHPFDHPDIVAGQATA
                     ALELLEQQPDVGTVLVPTGGGGLLAGVAIALHHLAPRVRVVGVQAAQAAAWPGSLAAGK
                     PVALDRMSTMADGIAVGLPGAVPFAHVAEYATHVVTVDEDALSSALLLCMERAKLIVEP
                     AGAAAVAALMTLSPEQLGLEGPVCAILSGGNVDPLLLTRLIGHGLGAAGRYLVLRVTIS
                     DRPGSLGRLLAEIGRTGASVFEINHSRTGAWLAVDEAEVALTLETRGPTHREDVLDALR
                     EAGYVVRVQE"
     gene            complement(16985..17959)
                     /locus_tag="AWN90_RS33710"
                     /old_locus_tag="AWN90_33735"
     CDS             complement(16985..17959)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014983532.1"
                     /locus_tag="AWN90_RS33710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33735"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_067591166.1"
                     /transl_table=11
                     /translation="MRSGGRAAVTVGVLITAAAVLAGCGGKVGNTGSADDKKIVLIPGV
                     ANEPFYISMQCGAQDEAKKLGYQLQTQAPTQFDASLQTPIVSGVIATKPGAILIAPTHA
                     TAMAAPMKQAKDSGIKVVEVDTHLDDTSVALSSISSDNAKGGQLAAQTLAKLVNNTGPV
                     LVINTKAGTSTTDQRAQGFEDELKSHPGMSSLGVQYNNNDAAQAASIVTATLAAHPDLA
                     GIFATNLSSAEGAATGLRNAGKLGQVKLVGFDASPKQVEDLKAGTVQALIAQDPAKIGA
                     QGVDEAAAAIEGKPVTRTIQTDMIAITQADMDANSRYFYKSKC"
     gene            complement(17988..19055)
                     /locus_tag="AWN90_RS33715"
                     /old_locus_tag="AWN90_33740"
     CDS             complement(17988..19055)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014983531.1"
                     /locus_tag="AWN90_RS33715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33740"
                     /product="ABC transporter permease"
                     /protein_id="WP_082871587.1"
                     /transl_table=11
                     /translation="MTEQTDEPVAAERAVNGTDIPALPKRTLLQRLTGASTVWIGAVLV
                     LLYIAFSIARPDAFPTRFTLQTLLIETSVLLVLSIGMTFVIITSGIDLSVGMVLIFSGV
                     IGSKIMEWLSPGQDATHAGWGIVAVGFLGSIAGGALWGLINGILVAKAKIPPLIVTLGS
                     FGAALGAAQLITGGVDTRTVPEKLRDSLGFGTLFGGIPNLVLVAAVVTLIGAWLLHTTR
                     FGRYTYAIGSSAEAARRSGIGVTRHLVLVYLMAGLLSGLAGFMNLAYFGTTTIGGHTTD
                     NLDAIAGVVIGGTSLFGGTGSVLGTVIGVFIPSVLRKGFVIVGVPVFWQPIAVSVVLVA
                     AVWFDQLRRRSRDRK"
     gene            complement(19052..19813)
                     /locus_tag="AWN90_RS33720"
                     /old_locus_tag="AWN90_33745"
     CDS             complement(19052..19813)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005167813.1"
                     /locus_tag="AWN90_RS33720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33745"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_067591169.1"
                     /transl_table=11
                     /translation="MPSVVLEAEGLVKRYGGVEALRGANFQVYAGEVVALIGDNGAGKS
                     TLVKCLSGAEQPDGGRILLDGEPVRMVSPTAARRLGVETVYQDLAVAPDLDPAANLFLG
                     RELFRRGLAGRLGMLDRKAMRTQAAEHFRRLGVTLPRADVPIGALSGGQRQTVAVARAV
                     LWASKVVFMDEPTAALGVVQRERVLEVIRRVREQGIAVVLISHNMPEVLAVADRIEVLR
                     LGRRVARLTSDATLEQLVGAMTGALTTEDAA"
     gene            complement(19952..20275)
                     /locus_tag="AWN90_RS33725"
                     /old_locus_tag="AWN90_33750"
     CDS             complement(19952..20275)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019046488.1"
                     /locus_tag="AWN90_RS33725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33750"
                     /product="multidrug efflux SMR transporter"
                     /protein_id="WP_067591172.1"
                     /transl_table=11
                     /translation="MTLLLLGLAIVSEVTATVSLKVSEGFSKAVPSVIVVIGYGAAFYF
                     LSQALKRGMSIGVAYGVWSAIGVAAVATIGALFLGEKLTLVQVGGIGLVILGVLALELG
                     GAH"
     misc_feature    20285..20299
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     misc_feature    20954..20967
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    20977..20986
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 ggccaggccc gcgcacatcg ccaccgcggc cagccgcgcg accggccgcc accggcgctg
       61 gtagatcagt tcgccgacgg cgaccgcgac cagcatgagc gcggattcca cggcgggaaa
      121 gacgtattcg accgaaatcg ccagatacag gaagacgaag accgggatcg gcccgcccct
      181 gccgcgggcg tatcgcaccg acgccgccca cgcgtgcacc atccaggcgg tgccggtcag
      241 cgaggtcacc cagctggcct cgtcgaagaa cagcagccag ccggtgagcg ggaaggcgat
      301 gcccgccacc gccgcccact gcacccggcc gccgtaggcc agacacaccc gatacacgcc
      361 gagcgcggcg atgatcgaga acaccagctt cacgaccgtg gccagcacca cgaggttgtc
      421 gacggagggc gcgatcagat cgatcagcag ctgcggcggg ttgaacaggc ccgcctcctc
      481 catggtgtag ttgccggtca tccactgctc gggattcagc agcggcagat gaccctcgcg
      541 caactggcgg cccagccaca cccacagcgg ggtgtactgg gattcgctgt cgtcggtgta
      601 gaagtggcgg aagttggcca gcaggaccgc gatatatccg gcgatcaccc cgacgacggt
      661 gagcaagccc cagcgataca cgtctctgcg cgactgctcc acggcgttcg gatcggaccc
      721 ggacgcggca tgttccggcg ccgcctcaga cactgcactg tcgcccacga gttcctgacc
      781 ctacttcaca gcctccgaaa ccgaccacct gcaccgtgtt agagttcacc ccgatccggg
      841 ctccggcagg acaccaggtc cggtgcgcac cgtcttcgaa agtcgaacca gctgatgccg
      901 attccctccg ctcgctcgca ccaccgcata cccgtcgcgc atgcgcgcgc gggcgggcac
      961 ccgggccggg cgcacgcggt ctcggtggtc gtgccggtgt atcgcggcga ggacaccatc
     1021 gccggtctcg tcgccgaact gcacgagctg tcgcggccca ccaccacgcc gggcggcacc
     1081 gccttcgtcg tcgacgagat cgtgctcgtg cacgaccacg gccccgatcg ttccgacctg
     1141 gtgctgcaac ggctcgaccg cgaatacgag caggtccgcg tggtgtggct gagtcgcaac
     1201 ttcggtcagg acgccgccac catcgccggg atggccgccg cgcgcggcga gtggatcgtg
     1261 accatggacg aggacgggca gcacgatccc ggattcatcg gcacgttcat cgataccgcg
     1321 ctgtcgcagc gggccgatct ggtgtattcc aagccgacca acacccgccc gcacggcgtg
     1381 ctgcgcaacc tcacctcgcg cgggtcgaag gtcgtgctgg ccacgctgtt cgccttcccg
     1441 gattcgaccc ggttcgagag ctaccggctg atccgcggcg atatcgggcg ccagctggcc
     1501 gaggtcgcct ccaacggcgt gtatctggac gtggcgctga cctgggtggt cgacaacacc
     1561 gcgcaggcgc cggtactgct gcgcgccgag ggccgggaga actccgggta caactaccgg
     1621 cggctgttct cgctgttctg gaagatggtg ctgtgcagcg gaactcgcgg cctgcgggtg
     1681 gtgagcatgc tgggcgtcac gctggcggcc agcggcctgg tgtacgcggc gatcatcgtg
     1741 tggcagaaga tgttcgggca cggcgacaac cccgagggct gggcctccac catcgtggtg
     1801 ctgctgctgg tctcgggcgc gatcctgttc tcgctggggc tgatcgcgga gtatctcggt
     1861 gtggcgctgc atattctggt gggcaaaccc ctgtatctga cggtagattc gcccacgccg
     1921 cgccccgacg ccgagacgcc ggcactgacc acgtccgcag cgatcggggg gaacaacccg
     1981 ggtgagtact gaccgcatca tcttcagccg cccccaccgc gccgccgggg agctcgcgaa
     2041 tctggaggcg gtgctggcct ccgatcacag ccacggcgac ggacccttca ccgcggcggc
     2101 caccgcgaag ctgaaggcga tcaccggcgc gccctacgcg ctgctgacca cctcgtgcac
     2161 gcacgcgctg gagatggccg ggctgctgct ggaactcggc ccggacgacg aggtgatcgt
     2221 cccgagtttc gcgttcacct cgaccgcgac cgccatggcg ctgcgcgggg ccacctgcgt
     2281 gttcgtggac atcgacgagc gcggcaatat cgatccggag tcggtggcgg cggcgatcac
     2341 tccccgcacc aaggcgatcg cgctcatcca ctacggcggc gtggccgcgg agatggaccg
     2401 gctgcaggag atcgccgacg cgcacggcat cgcgatcgtg gaggacaccg cgcacgcgct
     2461 cggcgccacc tggcgcgggc ggccgctggg cagcatcggc acggccgggg cgctgagttt
     2521 ccacgacacc aagaacattc actgcggcga gggcggcgcg ctgctgctga acgacgaaat
     2581 cctcatggcg cgtgcggaaa tcatccggga gaagggcacc gaccgggccc gcttcctgcg
     2641 cggcgcggtg gacaagtact cctggcagga catcggatcc agttatctgc ccagcgaatt
     2701 gaacgccgcg gtgctggatg cccaactggc cgagttcgat acgatccagg ccgggcggtt
     2761 ccgggtgtgg aacgcctacg ccgccgggct gccggattgg gcgcgccgca acgacattcg
     2821 cctcatgcag gttccgccgg atcgcgagca caccgcccac ctgtactacc tgcgcacgcc
     2881 gaccgaggac cgccgcgacg atctcatcgc gcacctgcgc gagcggggca tctcggcccc
     2941 gttccactat gtgcccctgg attccagccc cgcgggcctg aaactgggcc gcaccccgca
     3001 cccgtgcgtg cgcaccgccg aattctccgg caccctggtc cgcctgccgc tgtggccggg
     3061 cctgagcgat gcccaggtcc agcgcgtcct cgaggcggtc accgccttcg aggtgtgagc
     3121 ctcgaaagtc agtccggcag caccgttccc ggggcgggga gagtgccgtc gatcaggtag
     3181 cgggtgatgg cgtctcgggt ctggccgggg atcaggaacg aggtgtggcc gtcgccgttt
     3241 cgggtcagca ggaccgcgtt ggggatctcg gtggacagga gttgggccca gccgtagaag
     3301 gtggacgggt cgtgggtggc gttgatcagg agcggtgtga tcgtcggttt cgcgagtgcg
     3361 gtgtgcggtg ggttgctgaa agcgcccggc cagccttggc attgggccag gtagccgtag
     3421 gactggcccg cgcccagggt gtcgggggcg atggtttcgc cgaggatctg ctcggttttg
     3481 aacgcggcgt aggtgtcgta gtcggcgcgg aattcggcgc agccgacggc ctgtccggca
     3541 ttgccggtct cggtggccgc ctggggtgac aggccgctgg cgtcgccggg gcgtgcctga
     3601 tccaggtgcg tggccaggcc cgcccatccg gttccggacg cggaccgcgc gggcttgaac
     3661 agcaggccgt cctggatctg cgacagcagg tcgcccgcgc cgacctgggg ggcgcactgg
     3721 tgggaggccg cgcagccggg tgcggggagc ggggcctgcc gggcgcgggt cgccaggtcg
     3781 tggacgacgg cgacggcatc gtcggtgccc agggcgcagt cggtcgcgcc gcgacaccag
     3841 tcggcgaagc ggtgcaggct gtcctcgaac gcctcggcct cgtacacgtg catggagctg
     3901 ggtggcagcg aatgcaccag ggcgccgtcc agggcgaggg cgcggctgcc ggtcgggaac
     3961 aggcgcgcgt actcgaatcc gatctcggtg ccgtaggaca gcccgagata gttcagcggg
     4021 cccgcgtcga ggcgctgccg gatcacgtcc aggtcccggg ccaccgcgac ggtgtccacg
     4081 tgatcgagca gcgggccggt gcgggtgcgg caactgtcgc cgtaggcccg attcgccgcg
     4141 accatggccc gataggcggc ctcgtcggcg gggaagatgt cggtgagctt gttctgcagg
     4201 tcgggatcgc agcgcaccgc ggggcggctg gtgccgatgc cgcggggatc gagcccgacg
     4261 aggtcgaacc gggcccgcaa ttccggcggg aacaatgcgc cggggtgggt gctttcgccc
     4321 gcgacgagct cggtccccac cccgcccggc ccgcccggat tgacgaccag ggcgccgatc
     4381 cggtgactcg ggtccgaggc gggcagccga tcgatcccga ccgtgatctt gtcgccgtcg
     4441 ggcttgtccc agtccagcgg gacctcgata tccgcgcact ggacgagcgt gccgtacgcg
     4501 ggcgggcacg ccttccacgc gatcggcggc gcggcggggg tggtgctctt ggagccggat
     4561 ccgcaggccg cgcagaccgc cgccagcagc gccacggaca ggatcgacct cacgagtcgc
     4621 gttgttcgca ccgatcgagc gtagaacccg cacggtcata acacatccgg gacatccccg
     4681 atcttgttat tcgggggttc gcggtagctc gcggcgcata caggcgcgcg gccaggcgtc
     4741 caggccgtgc gcggcctcgg cggcgcgcgc ggcacgcagg ccgggtgtct cctgtgcgac
     4801 gggcagccgg tggaagccga ggcgctcgta atacggtccg ttccagggga cttcggtgaa
     4861 cgtcgtcagg gtcagcgccg caatcccgcg cgcgacggcc cattccgcgg cgtactcgat
     4921 gaggtcgcga cccagccgcc tgcccgcgtg atcgggatgc accgacacct ggtcgatgtg
     4981 ggcgttgccg tcgaccacgt cgaggatgag gtaggcgatc ggagtgtcgg tcgcgtcggc
     5041 gatcacccag gcgcggccgt cgtcggcgaa ggcccgcagc tgctcgatcg agggcggctc
     5101 gtcctcggcg accgacgaca ttccgatgtc ggcgaacggt tttcccgccg cccgctccaa
     5161 ttcgcgcaga cccggcaggt cggcctcgcg tgccgggcgg atcaccgcgt ggtccggcgg
     5221 agcagttggt cgagcacctc gggagtcagc ggctcgtagg tctcggtggt gcggtcgaag
     5281 taccaggtct tctcgccggg ctgcaggcgg accgcggcct ggacggcgcg ggtggagggg
     5341 cggtaggtgg aactgcgcgg aatctcgtcc accacgtaca ccaggtcggg gcgctgggcc
     5401 ggatcgaggg cgcgcaggcc ctcggtgacg tccttgggct cgagccggta gccccggcgg
     5461 aggctgaccg cggcgaccgc cagggtcgtg ccaccggcgg gcaggccgaa cgccacctcc
     5521 aggtcgaccg cggtgatgtc gttgagcgcg tccacgatcg gctgcgtgta gaccgggccg
     5581 tgcggggtct ggatcaccgt gtcgcggcgg tccatcagcc agtagtcgcc gtcgccgtcg
     5641 cggcggaaca ggttctcggt gggcatccag gcatcgcccg gcgtgaacac cccgcgcagg
     5701 ccgccgaggg agatgtcgac ggtctccgac gccttgccga tcagcaggcc cacctcgttg
     5761 tcggcggcgc ggcgcgcgaa accctgtgcg tcggtacgga tctcgccggt caccgaatcg
     5821 taggcgatga gctccaccct ggcggtgccg ggcaccgggc ggcccttgca gccggtcttc
     5881 gagccggaca cgttggccag caccacatct ccctcgatgg aggcgtagaa ctccagaacc
     5941 cgtgcgggag cgaacctttc ggtggtgcgc cgccacagcc cggcgggcat gccggacccg
     6001 atgaacagcc ggatcggatg cgggcgcccg tcggggaagg agtcggcgtc gaggatgtcg
     6061 cgcatcatcg tccacgtgta ggtgacgacg gtgacgccgt agcggtgcac ctcctcggcg
     6121 aaccgcgccg gatccagcga gcgcgccagc gcgatccggc tgccgcccgc caccgcgccg
     6181 cccaggctca ccaacagccc ggacgaatga tgcagcggcg caaggcaata cacggtgtcg
     6241 cggcgatcca ggtcggcggc ggtcgcggtg ccgaacgccg acagcgccca gcggtggttg
     6301 gtgatgtatt tgatgtcgag cttgtcgccg gtgccggtga cgagcacgaa cgccagttcg
     6361 cgcgccaggc ccggattcgg ccggtaccag ccgggcaggc gcacctgttc cggatcgatc
     6421 tgctcgaggt cgaccacctc gccgtcgtgc ggcaggtcca ggccgcgcgc gtcgccaccg
     6481 ccgagcacca gcacccgggc gccggtggcg gccgcgtccc gcagattctc cggatcggcg
     6541 acgagggtgc gggcgccggt tatttccatc gctcgttgta gttcgcctcc cggcgcgagc
     6601 agcacggcga ccgcgccgat ccgcgacagc gccgccaccg cgaccagcgc gctgggccgg
     6661 gtctccatga gcaccccgac ccgggcggcc gggcgcacgc cctcggagac gagcccgcgg
     6721 accacgttgt cgatgcgcac gttcatcgcg gcattggtgt gcacgcggtc gtcgaacagg
     6781 aagcactccc gcagcggcgc ccgccgcgcc tgctcgtcga gcaagcgccc caacgagatt
     6841 cgggtgtgcg actgaatcat gcccagccgg gtcaggcggg gcagcgcgcg ggccgcctcg
     6901 ccggtcagct ccaccgagcc gcgcagcgtg ctgcccgcga tgtcggtgag cgcctggccg
     6961 atcccggcgc cggcctcggc gagcgcggcg gcggtgtgca cgacgcgggt ggcggccgtg
     7021 cgccggcggg cggcgtcggc gggctcgtcc atcggctcga taccctcggg ccgctcgccc
     7081 ccgccaccga tccagcggat ccagtcgcgc accagcggcc aggtccgcgt ggtggccgtg
     7141 ctgcccgcga ccaggccgaa atggcccgcc atcaggctgg cctcgtagac gtcggcgttc
     7201 ggcgcggccc gcacgatgcc gcgcaccgcg accggctgcc cgatgtcgtc cacctcgccg
     7261 acgaacgcca ggatcgggca cctcagctcc gccagcgaca ccggctgatc gcgaatcacg
     7321 aacccgccca gcatcatccg gttgtgcgcg acgaactgct tgagcaggtc ggcggcggcc
     7381 ggaccggcgt agccgacgaa gccgtcctgc tggaggaagc ggcgctgccg ctccttgggc
     7441 agcagcgcct cgcggtcgtg cagctggcgc aggaagtcga cgcgggcctt ggcggtcttg
     7501 accggatcca gcatttgaaa gccgatgcgc accatggagt cggtgatcgg cagccggttg
     7561 agcacgtgat cggccacgaa atcggcgacg tcggacacca ggccctgcgg cagcccgaac
     7621 ggcagtccgg cgacgatgtc gaccgggctg ccgaaggtca cgatgctcgc cacgcccttg
     7681 ccgaagcggt aggcggtggt ctggtaggcg aacatgccgc cctgcgaata tcccatcagg
     7741 tgcacgccgc gcccggtcag ctcggtgacg gtatcgatgg cgctggacag ggccagcacg
     7801 tggtcggcca ggtcgcgctt ccagccgccc tcttccgtgg cgggagagcc gaaatcgatg
     7861 acccagcagt cgatcccggc gcgctgcagg atgcccaccg caccgccttc ggcgttcacg
     7921 tcgtagatgt cggcgctcac catgagcggc ggcacgaaca gcgcgacggg gcggcccggg
     7981 gtggtgtcgt cggggaagta gtgccgcagc cggtacatcc gcttgcgctc ggtgacctcg
     8041 tacggggagg actcgacgtc gtgggtcagc ccgccgaacc ggatcacttc cagcccgttc
     8101 tgcgcggttg ccagcaaccg ctgcaccgac cccaccacgg tcctcgtatc gaacttcacg
     8161 gtagctccca gccctcaacc cagcgcgtga cacccaccac agacccctgc gggtgctgtc
     8221 gagcttgcca catccccagc ctaacgcgac gccctgtgac gtgtcgcatg cgcgcaccgg
     8281 agtttcggca accgaccggc aatccagagc gtaggatccg acgggcacaa ccgcccttgg
     8341 atctgtccac accccgaatc gttgcgaagt cgtgacagct caacggattt caccaccagt
     8401 ttccccgatt ccaccacgac gcgcattccg ggtgccctag catattcgcc ggaacgcact
     8461 gtcgcgcttg ccaattcgct catgtctcga tcgcaggctt atttctgcat gcctgccgca
     8521 cagctgtcag cattcgccac cccgactcgg cggtggccgt ctccacgtga ggacgcagca
     8581 tgacgatcga ccttccaccc cagatcgaaa accatgttcg taagagcctt tccaccggcg
     8641 ccgcgcgcaa tctggcgcac accaccaagt ccgagccgca gatgcagggc atcacctccc
     8701 ggtggctgac ccgcaggctg ccgtggaccg aggtcagagg cggtgtgtac cgggtcaatc
     8761 ggcgactgac ctacaccctc ggcaacggtg agatcgagtt cgacgtcgac ggcccgcagg
     8821 cccgcgtcat cccggtcgag ctgcgcgagc tgtcgcagct gcgggacatg gaggacgagg
     8881 acatcctggg cgccctcgcc ggaagtttcg aacagcgcga cctcgacccc ggcgagatcg
     8941 tcgccgaatt cggcaacccg atggatcagc tggtcctggt cgtgcacggc aagctcagca
     9001 agctcggcac gggcgagtac ggcgagaccc tcgggctggg cgtgctggcc ggtggcatgc
     9061 acgccggtga tcgcatgctg gtcgaccggg acgccatctg gccgttcacc gtgcggaccc
     9121 tcaccccgac gacgctgctg gtgctgtccc gggccgggct ggaacgcgtg ctggaccagg
     9181 cgccggccct gcgcgagcat ctggaccgcg tcgccgccgg gcccgcccgc ccgcagacca
     9241 agcacggcga ggccgagatc gacattgcct ccgggcactc cggcgagccg ctgatccagg
     9301 gcaccttcgt cgactacgag gccaaccccc gcgagtacga actcagcctc gggcagagcg
     9361 tgctgcgcat ccacacccgc gtcgcggacc tgttcaacga gccgcacaac cagatcgaac
     9421 agcagctgcg gctgaccatc gaggccctct acgaacgccg cgaacacgac ctggtgaaca
     9481 acaccgactt cgggctgctg cacaactgcg atctcaagca gcggatccac accgagaccg
     9541 gcgcgcccac cccggacgac atggacgagc tgctgagcat gcggcgcagc acgaaactgt
     9601 ttctggcgca cccgaaggcg atcgccgcgt tcgggcgcga atgcagcaaa cgcgggctgt
     9661 accccgatcc ggtcgaggtc gacgggagcc gcgtcccggc ctggcgcggg gtgccgatct
     9721 tcccgtgcag caagatcccg gtcagcgaca cccagaccac ctcgatcctg gccatgcgca
     9781 ccggcgagca ggaccagggc gtaatcggcc tgcaccagac cggaattccg gacgaatacg
     9841 agcccagcct caatgtccgc ttcaagggca tcgacgacca gtcgatcatc tcctacctga
     9901 tcagctgcta ctactccgcc gccgtgctgg tccccgacgc gctgggcatt ctcgacaacg
     9961 tcctcgtcgc ccggcactcc gactgaccgg aagggcaacc atgtcggtgc tgtcccgcgt
    10021 cgcggcgcca ccggccaccg atgacgtggc cgatgtgatc gcggcgctgc tgaccaatct
    10081 cgagggcgcg cccgcccccg agctgtcgct gtcgaccgag gcggaagccg ctgtcccccg
    10141 gttcgattcg aacctgctgt cgggaatggt cgcgcgcgcc gtgccccggc gactattagg
    10201 tccggtgggg ctcggcgcgg cgagcctgct ggtggaaccg cccggcggcg cgcgcgagtc
    10261 gcccgcggcc gcgaccggct cggcgattcc gccgctgtac tgcccgccgc cggtccggga
    10321 cgacccggcc ctggccgagg ccgtcaacgc gggaatcatc tcctgggccc aggccatcgg
    10381 gctctacgag gggcgcctgg acgagctgca ccgggccgac ttcggtcggc tgatcatgct
    10441 cgcccatccc gactgcgacg accccgaccg gctgctggcc gcggcgaaat gcgccgtgtc
    10501 ggagtggtcg gtggacgact actactgcga ggaggacgcc gacgaccgcg cacccgacgg
    10561 cagcccctcc agcgccgagg ccgagctcgg cccgcggctc gaattggcca tggccgccat
    10621 cgatccggtg catctgccgg accgctacca ggtccagctc gaacgggcgc tggacgccga
    10681 tccgatcctg cgggccttcc gcacctcctt cgatcatctg gcgcactacg ccacgcccgc
    10741 ccagctggcg cggctgcgca ccgagatcgg cggctggttc atcgcgctcg gcgcggaggc
    10801 gggctggcgg gcggcgggcc ggatgccgcc ggtgtgggag tacctgacca accggcaacc
    10861 gcacagtttc ctgccgtgca tggcccctat cgacgccgtc ggcggctacg agctcggggc
    10921 cgccgactac accgatcccg cggtgcgccg ggtggtcacg acggcggcgc tggccgcgca
    10981 gatggtcaac gacctgtact cgatggcacg cgaagacctg tccggcggac gggaattcaa
    11041 cctgcccacc gtcctggcgg cggaggagaa ctgctcgcgc cgggaggcgg tggggcacac
    11101 cgccgcggtc cacgacgagc tggtgcaccg cttcgaacgc gaggccacgg tgctggcggc
    11161 gaccgcgagc ccgcagctgc gccgcttcct cgccgggctg tgggcctgga tgggcggcaa
    11221 ccgcgcctgg cacgcggaca gccgccgata tcgcgaaacc gagtgacacc cttcgagcga
    11281 gaggatgatc cgtcatgacc acgctggact cccctaccga cagcgttctg cgcaccagct
    11341 atcagcgctc cgtggcggcc tactggaacg acaaccccaa cgacgaccgc gtcaatacca
    11401 agctgggcga ggtcgacggc ctgtaccacc accactacgg catcggcgaa cccgacctct
    11461 cggtgctcga gggccccgcc gacacccgcg aggaccgcat cgtccgcgaa ctgcaccggc
    11521 tcgagaccgc gcaggccgac ctgttgctcg accacctcgg tccggtcacc gcgggcgatc
    11581 ggctgctgga cgccggatcc ggccgcggcg gaacgagttt catggccaac gagcggttcg
    11641 gctgccaggt ggacggcgtc acgatctcgg agtaccaggc gggtttcgcc aacgatcagg
    11701 cccgcgagcg cggcgtggcc gagcgggtgc ggttccactt ccgcaatatg ctcgacaccg
    11761 gcttcgactc cggcagccgg cgcgggatct ggaccaacga gaccaccatg tacgtcgacc
    11821 tgttcgacct gttcgccgag ttcgcccggg tgctggcgcc gggcggccgg tacgtgtgca
    11881 tcaccggctg ctccaacgac gtcaccggcg gccgctcggc ggcggtgagc tggatcgacg
    11941 cccactacgg ctgcatgatc catccgcgcg gcgagtattt ccgcgccctg gccgcacaca
    12001 acctggtacc gatcgccgtc gtggacctca cccccgccac catcccctac tgggaactgc
    12061 gcacccactc cgaactcgcc accggcgtgg agaaaccgtt cctgtcctcc tatcgggacg
    12121 gaagtttcca gtatctgttg atcgccgccg ataaagtggg gtcgtgagcg ccgactgcga
    12181 tacgcccccc tccggccgtg aggccctgct cgtggaactg gtcgacgaac agggccaccc
    12241 gatcggatcg tgcacggtgt ccgaggcaca caccgcgccc ggacacctgc accgcgcctt
    12301 ctcggtgctg ctgtacgacg acgaggggcg cgtgctgctg cagcagcgcg cctcggtcaa
    12361 gacccggttc ccgctgcggt ggtccaacgc ctgctgcggg catcccgcgc cgggccagtc
    12421 cgtcgcggcc gcggcggccg tgcggctggc cgaggagctc ggggtggagg ccgacccggc
    12481 cgacctcacc gaggtcggcg tctaccggta ccgcgccgag gatccggcga ccgggcgggt
    12541 cgaatccgag tgggatcacg tgctgatcgg tcgcttcgaa ggcgttccgc cgcagcccga
    12601 tccgggcgag atcgacggcc acgcctgggt gcgcccgcag gcgctcaccg aggcgctggc
    12661 cgccgctccc gccgactaca cgccctggct ggccggtgtg ctcgccgccg ccgagcaggg
    12721 cagggccagc gggctggcgc cgatcgtcag cgactgatcg ccgggcggcg ccagcagcac
    12781 gtcgatcaca tgccggtcga tcaggtcgct gagcgtgtat ttgtccagtt cctggtagaa
    12841 cgcctcctgc gcgtcggcca gcgcgtgccg ccaccggcac gcgcccgcca gcgggcacgg
    12901 ctggtccccg tggcaatcga cgaccgcgga accaccctcg agctcgcgca cgatcccgcc
    12961 gaccgaggcc gaacgccccc gctcggtgag cacgattccc ccggctctgc cgcgctgcgc
    13021 ggcgatcagg ccgaggtccg acaatttggt caccgccttg gcgacatagt gttccgaggc
    13081 gttgatctgt ctggcaatga gcttggtggt aacgcgttcg tcaccgctcc ggctgaccgc
    13141 gagacgcatc atcgcgcgaa ggccgagatc ggtaaaccgg gagagctgca tacccccacg
    13201 ctacttattt ccgactggaa tgagcgtgat tctcggctgt gagtcaccta cgaactcgat
    13261 aacggcccgc caacgaccga tggacgatga ggcccaggcc acagccgatg aaccagctgt
    13321 attgcgcggc cgtatacatg ccgggcaccc gcgtggcgag caccggaatc accgccacca
    13381 ccgcgccgac gacggtcgcg acgatcgccg ccgggttgaa tccccgccga taccagtagc
    13441 ttccgcgctc ggaccgggtg aacaggtcgt cgacgacgat gcgccgcccg cgcaccaggt
    13501 agtagtcggc gatgagcacc ccgaacagcg ggccgatgaa cgcgcccagc acctccagcg
    13561 tgtagtggat gacctgcggg ttgttgtaca gattccacgg cgtgatcagc accgatccga
    13621 ccgcggcgag catgccgccg gcgcgccagc cgatctgctg cgggcgcacg ttcgagaagt
    13681 cgaaggccgg ggagatgaag ttggcgacga tattgatgcc gacggtcgcg acggtgaagg
    13741 tcaacgcgcc caacacgatc gcgaaggtgt tgtcgatgcg ggccacggtc tgcaccggat
    13801 cggtgatcag cgtgccgtag acgggcacgg tcagcgcggc ggtgatgacg accagcagcg
    13861 agaacatgag aaagttcaca ggcagcccca gcaggttgcc gcgccgcacc gcgcgcatcg
    13921 atcgggcgta gcgggagaag tcgccgaagt tcagcatcgg ccccgagaag tacgacacca
    13981 caagcgcgat cgcgcccagc atgaccggta tcgagtccac tcccgagtac cgcacccggc
    14041 ccagattcag gtcgatcgca ccccacccgg ccttcgcgat caggtacccg cacagcgcga
    14101 acatcacgac atacactgcg ggaccgcaga agtcgatgaa ccgccggatc gactccatgc
    14161 cgcgccagaa cacgcacgcc tgcaccgccc acagcagcag gtatccgccc cagcccagca
    14221 gcgacagccc caggaagccg tagtcgccga ccaccgcgta ccgggccagg cccggaaaca
    14281 gtttcaccgc gacgacgatc agcgcggccg aggccagata ggtctgaatg ccgtaccacg
    14341 ccaccgcgat caggccgcgg atgatcgcgg ggatgttcgc gcccagcacg ccgaacgcgc
    14401 tgcggcacac caccggatac ggcaccccgg cccgctggct gggcgcggcc accagattgc
    14461 acaggccgta gacgatgccg atcccgatca ccagggccag cagcacctgc cagctggcca
    14521 ggccgagggc gaacaggctg cccgcggtga cgtagccgcc gacgctgtgc acgtccgaca
    14581 tccagaaggc gacgatattg tatgtgcccc accgctgttc gcgcagcggg gccagatcgg
    14641 cgttcgtcag gcgcgggtcg tagccggtgg cccgcgccgc ggtggccggg ggaatggtct
    14701 cggtcatggt gcgtccgatc cgaattcgtg acagaagcac cgacgctacg atccggccat
    14761 tgcccgggca ttgcccgttt attgccccga tattgcgcac aacatatatc gttccgagcg
    14821 gtacggaatt gtgcgggagg ctattcgaac atcgtaccga gaatgcggcc ggtgcccgtc
    14881 cgcacgcccg cgcccaggca gccgccgacg gtctccgggg tgaccatgtc gtaggcgacc
    14941 gtgatccgga cgcggcggcc gcggcccagc ccgtcggtca cctcgagtgt gccggtcgtc
    15001 ggctgcgcca tcgccaccgg ccacgggccc gccaccgtgc tggtctcgcc gtcggaccag
    15061 gtgatggcga gggtgatcgg gccgtcggcc gggtgcatgc agtccgacca cgcggtgtgc
    15121 acgccggtga aggtcccgcc ggtgatgccg gggaccaccc ccgcgcagtc gcgcagcgtc
    15181 ccggccgagg tgaaggtcag ccactgcggg gtcatggtga tcgccccgtc ggcggccgtc
    15241 cagcggaatt cgccgccgtc gcatcggccg agcggttccg cggccgccgg gcccgacccg
    15301 ctcatcgccg cacccgccag cagcgcgatc accggcagcg ccgccatcct gccgaacctc
    15361 gtcatggcct cacctttcgg tcgcccacgg atgaagcacg atcatgtgat cgctactctc
    15421 ccaccccacc cggcagccgc ggcgttccgg ccgcgtgtcc gcctccggca ttaccgcggg
    15481 ctccgcgcgt cggccccggc acacacgccc gatgctccgg cctccgatgc tgtcggtgat
    15541 ccgggctcgc ggctgggcaa agtgcgcagc ggggcgtgat ctaccgggcg gtagttgcgc
    15601 agcccgccgg ggccgcgacg ctcgggcttc tcgggcagga cttgtctggc agcatggccg
    15661 ccatggagtt gatcgggccg gatcgtctcg aggccgccgc gaagctgttg gagccggtga
    15721 tccggcggac gccgctggtg gcgtcgcggg tgctgtcgga gcgcaccgga ttcgaggtgc
    15781 ggctcaagtg cgagaacctg cagcgcaccg gatcgttcaa gccgcgcggc gcctacaacc
    15841 gcatcgcgaa cctccccgaa cgcgaccgga agcgcggcgt ggtggccgcc agcgccggca
    15901 accacgccca gggagtcgcc tgggccgcaa gcagtctcgg catcgactcg acggtgttca
    15961 tgccggtcgg cgcgtcgctg ccgaagctgg tggccaccag gtcgtacggg gcgacggtgt
    16021 accaggtggg cgagacgatc gagcaatccc tcggcgcggc actggaattc gccgagcgga
    16081 ccggcgcgac gctgatccat ccgttcgacc atcccgatat cgtcgccggg caggccacgg
    16141 ccgcactgga actgctggag cagcagcccg acgtcggcac cgtgctggtg cccaccggcg
    16201 gcggcgggct gctggccggg gtggcgatcg cgctgcacca cctggccccg cgggtacggg
    16261 tggtgggcgt gcaggcggcg caggcggcgg cttggccggg gtcgctggcc gcgggcaaac
    16321 ccgttgcgct ggaccggatg tcgacgatgg ccgacggcat cgcggtcggg ctgcccggcg
    16381 cggtgccgtt cgcgcacgtg gccgagtacg ccacgcacgt ggtcaccgtc gacgaggacg
    16441 cgctgtccag cgcgctgctg ctgtgcatgg agcgggccaa gctgatcgtg gaacccgcgg
    16501 gcgcggcggc ggtcgcggcg ctgatgacgc tgtccccgga gcaactgggc ctcgagggcc
    16561 cggtgtgcgc gatcctgtcc ggcggcaatg tcgacccgct gctgctgacc cggctgatcg
    16621 ggcacggcct gggcgcggcg ggccgctatc tggtgctgcg cgtgacgatt tcggatcgac
    16681 cgggcagcct gggccgcctg ctggccgaga tcggccgcac cggcgcgagc gtcttcgaga
    16741 tcaaccactc ccgcaccggc gcctggctgg ccgtcgacga ggccgaggtc gccctcaccc
    16801 tggaaacccg cggccccacc caccgcgagg acgtcctgga cgccctgcgc gaggcgggat
    16861 acgttgtgcg ggttcaggaa tgagcgctac ctagtccgac gccgctcccc cgggcccggc
    16921 gccgctcccc cagatcccga cgcagcccac ccccagatcc cggcatgctt ttggccggga
    16981 cccctcagca cttgctctta tagaaatacc gcgaattcgc atccatatcg gcctgcgtaa
    17041 tagcgatcat gtcggtctga atagtgcggg tcaccggctt cccctcgatc gcggccgccg
    17101 cctcgtccac cccctgcgcc ccgatcttgg ccggatcctg cgcgatcagc gcctgcaccg
    17161 tgcccgcctt caggtcctcg acctgcttgg ggctggcgtc gaacccgacc agcttcacct
    17221 ggcccagctt gcccgcgttg cgcagtccgg tggcggcgcc ctcggccgag ctcaggttgg
    17281 tggcgaagat accggccagg tccggatgcg cggccagggt cgcggtcacg atggaggcgg
    17341 cctgcgcggc gtcgttgttg ttgtactgca cgccgagcga gctcatgccg gggtggctct
    17401 tcagctcgtc ctcgaagccc tgggcgcgct gatcggtggt ggacgttccg gccttggtgt
    17461 tgatgaccag caccgggccg gtgttgttca ccagcttggc cagcgtctgc gccgccaact
    17521 gcccgccctt ggcattgtcg gaggagatcg acgacagcgc gacggaggtg tcgtcgaggt
    17581 gggtgtcgac ctcgaccacc ttgatgccgg agtccttggc ctgcttcatc ggagcggcca
    17641 tggcggtggc gtgggtcggg gcgatcagga tggcgcccgg cttggtggcg atcacgcccg
    17701 agacgatcgg cgtctgcagc gaggcgtcga actgggtggg cgcctgggtc tgcagctgat
    17761 agcccagctt cttcgcctcg tcctgcgcgc cgcactgcat ggagatgtag aacggctcgt
    17821 tggcgacgcc cggtatgagc acgatcttct tgtcgtccgc gctgccggtg ttgcccacct
    17881 tgccgccgca gcccgccagc accgccgcgg cggtgatcag cacgccgacc gtcacggcgg
    17941 cgcgtccacc acttctcatc tccgcctcac cttcgaaagg tcctgtgtta cttccggtct
    18001 cgtgaccgcc gccgcagctg gtcgaaccag acggccgcca ccagcacgac gctcaccgcg
    18061 atcggctgcc agaacaccgg cacgcccacg atgacgaatc ccttgcgcag caccgacggg
    18121 atgaacaccc cgatcacggt gcccagcacc gacccggtgc cgccgaacag actggtgcca
    18181 ccgatcacga cacccgcgat ggcgtcgaga ttgtcggtgg tgtgcccgcc gatggtggtg
    18241 gtgccgaagt acgcgaggtt catgaaaccc gccagccccg agagcaatcc ggccatcagg
    18301 tagaccagga ccaggtgccg ggtgacgccg atgccggagc ggcgggcggc ctcggcgctg
    18361 gagccgatgg cataggtgta gcggccgaat cgggtggtgt gcagcagcca ggcgccgatc
    18421 agcgtgacca ccgcggcgac cagcaccaga ttcgggatgc cgccgaacag ggtgccgaaa
    18481 cccagtgagt cgcgcagctt ttccggcacc gtgcgggtgt cgacgccgcc ggtgatgagc
    18541 tgggcggcgc ccagggccgc gccgaacgag ccgagggtga cgatcagcgg cggaatcttg
    18601 gccttggcca ccaggattcc gttgatcagg ccccagagcg ccccgcccgc aatcgatccc
    18661 aggaatccga ccgcgacgat gccccagccg gcgtgcgtgg cgtcctggcc cgggctgagc
    18721 cactccatga tcttcgaccc gatcacgccg gagaagatga gcaccatccc gaccgacaga
    18781 tcgatgccgg aggtgatgat cacgaacgtc atgccgatgg acagcaccag cagcaccgag
    18841 gtctcgatca gcagcgtctg cagggtgaac cgggtcggga aggcgtccgg ccgcgcgatg
    18901 ctgaacgcga tgtagagcag caccagcacc gccccgatcc acaccgtgct cgcccccgtg
    18961 aggcgttgca ggagggtgcg tttcggcagc gcggggatgt cggtgccgtt gacggcgcgt
    19021 tcggccgcga cgggttcgtc ggtctgttcg gtcatgcggc gtcctcggtg gtgagagcgc
    19081 cggtcatcgc gcccacgagt tgttccagcg tcgcgtcgga ggtgaggcgg gcgacccggc
    19141 ggccgaggcg cagcacctcg atgcggtcgg cgaccgccag cacctcgggc atattgtggc
    19201 tgatgaggac caccgctatg ccctgttcgc ggacgcggcg gatcacctcc agcacccgtt
    19261 cgcgctgcac cacgcccagg gccgcggtcg gctcgtccat gaacaccacc ttgctggccc
    19321 acagcaccgc gcgcgccacc gccaccgtct gccgctggcc gccggaaagc gccccgatcg
    19381 ggacgtcggc gcgcggcagc gtcaccccca ggcgccggaa gtgctcggcc gcctgggttc
    19441 tcatggcctt gcggtcgagc atcccgagcc gaccggcgag gccgcggcgg aacagttccc
    19501 gcccgaggaa cagattggcg gccggatcga gatcgggggc gacggccagg tcctgataca
    19561 ccgtctccac gcccagccgc cgcgcggcgg tcggcgagac catccgcacc ggctcgccgt
    19621 cgagcaggat gcgcccgccg tcgggctgtt cggcgcccga gaggcatttc accagtgtgg
    19681 atttcccggc cccgttgtcc ccgatgagcg cgacgacctc gcccgcgtac acctggaagt
    19741 tggccccccg caacgcttcc acgccgccgt agcgtttgac cagcccctcg gcttccaaca
    19801 ccacggaagg catctgcttc tcaccccggc tacctcgaca gaacggacgc ctcgtccgct
    19861 tcggccgatc gtagtttcgc gcgcgacgcg ccggggcgga ttcggcgaag atcatctccg
    19921 ccgtgcagga atccccatcg gcgcgggccg ctcagtgggc tccgccgagc tcgagcgcca
    19981 gcacgcccaa gatcaccagg ccgatccccc cgacctgcac cagggtcaac ttctccccca
    20041 ggaacaacgc cccgatggtc gccaccgccg ccaccccgat cgccgaccac acgccgtagg
    20101 cgacgccgat cgacattccc cgcttcagcg cctgcgacag gaaataaaac gccgccccgt
    20161 acccgatcac gacgatgacc gacggcaccg ccttagagaa cccctcggac accttcagcg
    20221 ataccgtcgc cgtcacctcg gacacgatcg ccaaccccag cagcagcaat gtcattgccg
    20281 cagaataacc atcgtcgatg agcggcccta ccgcgcgcgg gcctcggccg ccgccgcgcg
    20341 gacctcgtcg agctgcttgg ccacctgcac cccggcggtg ccgccgcggg cgttgcggga
    20401 ggcgatggag ccctcgacgg tgagcacctc gcggacggcg ggggtcagcg ccgggtcgac
    20461 ggccgcgaat tcggcgtcgg tgagctcgtc caggccgacg ccgcgggcct cggcggcgcg
    20521 cacgcacgca ccggcggcct cgtgcgcgac gcggaacgga acaccctggc ggaccagcca
    20581 ttcggcgata tcggtggcga gggtgtaccc ggcgggggcc agggcggcca tccggtcggt
    20641 gtggaaggtg agggtcgcga ccagaccggc gatggcgggc agcagcagct ccagctgggc
    20701 caccgagtcg aacagcggct ccttgtcctc ctgcaggtcg cggttgtagg ccagcggctg
    20761 cgccttgagg gtggccagca ggccggtgag gttgccgatc aggcggcccg ccttgccgcg
    20821 ggtcagctcc gagacgtccg ggttcttctt ctgcggcatg atcgacgagc cggtggacca
    20881 ggcgtcggcg agcgtgacgt agccgaattc cggtgtgctc cagatgatca cctcctcggc
    20941 catgcgcgac aggtcgaccg cgatcatggc gaacacgaag gcggcctcgg cggcgaagtc
    21001 gcgggcggag gtggcgtcga tcgaattggc cgcggccgca tcgaaatcca ggtcggccgc
    21061 gatggcctcc ggatccaggc ccagcgagga gcccgccagc gcgccggaac cgtagggcga
    21121 caccgcggcc cgcttgtcga agtcgcgcag ccggtcgata tcgcgcagca gcggatgcgc
    21181 gtgcgcgagc agatgatgcg ccagcagcac cggctgcgcc gcctgcagat gggtcttgcc
    21241 cggcatgacc gcgtccggat gcgcgg
//
