LOCUS       NZ_KV411304            23631 bp    DNA     linear   CON 12-FEB-2024
DEFINITION  Nocardia terpenica strain IFM 0406 scaffold2, whole genome shotgun
            sequence.
ACCESSION   NZ_KV411304
VERSION     NZ_KV411304.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardia terpenica
  ORGANISM  Nocardia terpenica
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 4638951)
  AUTHORS   Buchmann,A., Eitel,M., Koch,P., Schwarz,P.N., Stegmann,E.,
            Wohlleben,W., Wolanski,M., Krawiec,M., Zakrzewska-Czerwinska,J.,
            Mendez,C., Botas,A., Moris,F., Cortes,J. and Gross,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-APR-2016) Pharmaceutical Biology, University of
            Tuebingen, Auf der Morgenstelle 8, Tuebingen 72076, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 30-JUL-2014
            Assembly Method                   :: CLC NGS Cell v. 7.0.4
            Genome Coverage                   :: 118.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/12/2024 01:56:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,832
            CDSs (total)                      :: 8,760
            Genes (coding)                    :: 8,562
            CDSs (with protein)               :: 8,562
            Genes (RNA)                       :: 72
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 40 of 198
            Pseudo Genes (incomplete)         :: 174 of 198
            Pseudo Genes (internal stop)      :: 9 of 198
            Pseudo Genes (multiple problems)  :: 23 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:51:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2720940
            Orig. end                         :: 2744571
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KV411304.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23631
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="19"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23631
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23631
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13631](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13631)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    826..839
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.1"
                     /tool="antismash"
     gene            complement(1548..2561)
                     /locus_tag="AWN90_RS33350"
                     /old_locus_tag="AWN90_33375"
     CDS             complement(1548..2561)
                     /GO_function="GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013087.4"
                     /locus_tag="AWN90_RS33350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33375"
                     /product="methyltransferase"
                     /protein_id="WP_067596043.1"
                     /transl_table=11
                     /translation="MPDVATDPDAILARLTDVATPYAVRAAVTLGVPELLADGPASLGE
                     LAAATGVDADTLGRLLRYLVAHGLFGEPEPQRYALTDVSRGLIGEAGAARRAWMDLSGP
                     GARMDAAYGGLAHALRTGGDGYSAVHGRPLWEDLADKPRLRAEFDTLMGTDTATVAHLV
                     ATEYDWTGIEHVIDVGGGAGILLTEILRARPSMRGTVVDLPRAVDTARQRFAAAGLGAR
                     ADAIGGSFFEPLPAGADAYIVSRVLTDWNDQAAHDILRNCVAAARPGGRVLIVEVLPDD
                     SVLAPDSPYDLQMLAVVGGRLRDADQFTALAARAGATVAGVRRWDGGLTVIDCRPR"
     gene            complement(2591..3520)
                     /locus_tag="AWN90_RS33355"
                     /old_locus_tag="AWN90_33380"
     CDS             complement(2591..3520)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF025017.4"
                     /locus_tag="AWN90_RS33355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33380"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_067591007.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.4e-07,
                     bitscore: 29.5, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGPAFGVVIVTWNPTPGNVEHAISLARRGIQVCVVDNTPVPQPW
                     YARLTDAGITVLHNGNEGGLGGGFNRGIDLLAGRGAEVFFLFDQDSEPGDDYFDAMLAT
                     PRPEGSAPLLAGPVIYDRGTGIFLLGNEVVDADTIAAHAKNGPLEAPFVISSGTMITRD
                     AWQAMGPFDERYIIDYLDWDLCLRATRRGVRVVVNTGVVLRHSVGAFEIRSLLGRSMLA
                     FHYPPFRRYYTARNCVHFTTRNARHRAELLRLNAHLISNVLSIGLFERDRTSKLLALAA
                     GVVDGALGRLGHFTDTRPHLAALVARSR"
     gene            complement(3517..4707)
                     /locus_tag="AWN90_RS33360"
                     /old_locus_tag="AWN90_33385"
     CDS             complement(3517..4707)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011207991.1"
                     /locus_tag="AWN90_RS33360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33385"
                     /product="acyltransferase"
                     /protein_id="WP_231951748.1"
                     /transl_table=11
                     /translation="MSSGVFGYWTVPVTGDFDPDAMRAAFTALQHAYPVLGCRIVTLED
                     GDRLVRPTEFPAEGAWVRAGDPEPVRAPAGFTDPDRQLAYLDIVCGRDGARVTLFVHHS
                     IADARHDMELFARLWDLYAGHPASVADLPAPQDYPQSLEWHVTTRGIERGPRSGLEPVY
                     RPMPDEPETVGEIPYRNILARPDRLILDAEITTGIVESGRRTGLSVNSLVSAALLRAYA
                     TVASTDGSPVPVGVLAAVDLRSRLLPAVSATGGTTMSTFACFDAEIETATAATDLARRI
                     GDRLRTDLDSGVVAQSVLHFPDLFGDTRKHSLAGHISLTNLGAIPALRTPAGLTVTDYE
                     TGFHLAHPRPSAADSPAALLQVYTYAGRMTIGYVGDHLGTDAVLDAIRAELTEVSR"
     gene            complement(4769..5752)
                     /locus_tag="AWN90_RS33365"
                     /old_locus_tag="AWN90_33390"
     CDS             complement(4769..5752)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04444.1"
                     /locus_tag="AWN90_RS33365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33390"
                     /product="FkbO/Hyg5 family chorismatase"
                     /protein_id="WP_197696563.1"
                     /transl_table=11
                     /translation="MRAVRSALSCDYENAATAVTGRRALAVVEFGAEEGPAELRDGVPV
                     VRIRAAATESAGFREVWITDGDARTGHTDGLVYAHDDDILFCAGHIRHGDRYAAHTRER
                     YAAAFGLADALGYPTLVRMWNYVGDINAANADGLEIYRDFCLGRAEAFAAHGKAMPAAT
                     GVGTHGSGVVFYFLSCRSGGVTHIENPRQIPAYRYPRRYGPKAPTFARATHLLPDGGSD
                     TLFVSGTAAILGHETVCPGDVARQCEVALANIRELVGEQNLGRYGIAKPYGLSAIRRAK
                     VYVRHREHLEVVRRACAAALPPEAEIAYLVVDICRRDLLVEIEAVA"
     gene            complement(5721..7355)
                     /locus_tag="AWN90_RS33370"
                     /old_locus_tag="AWN90_33395"
     CDS             complement(5721..7355)
                     /NRPS_PKS="Domain: AMP-binding (12-424). E-value: 7.7e-87.
                     Score: 283.4. Matches aSDomain:
                     nrpspksdomains_AWN90_RS33370_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="AWN90_RS33370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33395"
                     /product="AMP-binding protein"
                     /protein_id="WP_156674583.1"
                     /sec_met_domain="AMP-binding (E-value: 3.7e-90, bitscore:
                     300.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLSSGSLGGAMWEWARRGGDRVALWDDAGAVSYAALARRADALA
                     VVLREVGIGRGDRVLMQLPNGWELVVGMLAVQRAGAAAIPALMGHRLHDLTRIAETAGV
                     AAVFTVDTHQGHDHRGDAHRLAAGRPVFVAGEDVGAADIDLRRACEHRVEEADRVRADL
                     DRHDPDVDEDAVILLSGGTTGRPKLVPHTHRDYRHAFRACAAASGVDAATVYLAALPVA
                     HNFSLASPGILGVLDAGGTVVLGRSPSPEAAFAAIARHGVTMSALVPAVARRWAEHARS
                     SPAARAAVAGLRLLQLGGAVTPPDLAAEVEGALGVTVQQVYGMSEGPVCMTSPDDPPEF
                     RYHTQGLPVTGDEIRLLDTAGQEADAGTVGEVVTRGPSLVRGYLGAADDSAFTADGWYH
                     TGDLARRRADGRIDIAGRIKDLVNRGGEKISVVEVETVLYGLPGIAAAAVVSLPHPDLG
                     ECIAAAVVPAAGTAVDLPRVRKFFADTGVAAHKTPDALFVVDDIPRTGMGKVDRPTLRD
                     RLTAARSAANDNAKDGVRACGTVGAEL"
     aSDomain        complement(6084..7319)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AWN90_RS33370_AMP-binding.1"
                     /evalue="7.70E-87"
                     /label="AWN90_RS33370_AMP-binding.1"
                     /locus_tag="AWN90_RS33370"
                     /protein_end="424"
                     /protein_start="12"
                     /score="283.4"
                     /specificity="substrate consensus: diOH-Bz"
                     /tool="antismash"
                     /translation="WEWARRGGDRVALWDDAGAVSYAALARRADALAVVLREVGIGRGD
                     RVLMQLPNGWELVVGMLAVQRAGAAAIPALMGHRLHDLTRIAETAGVAAVFTVDTHQGH
                     DHRGDAHRLAAGRPVFVAGEDVGAADIDLRRACEHRVEEADRVRADLDRHDPDVDEDAV
                     ILLSGGTTGRPKLVPHTHRDYRHAFRACAAASGVDAATVYLAALPVAHNFSLASPGILG
                     VLDAGGTVVLGRSPSPEAAFAAIARHGVTMSALVPAVARRWAEHARSSPAARAAVAGLR
                     LLQLGGAVTPPDLAAEVEGALGVTVQQVYGMSEGPVCMTSPDDPPEFRYHTQGLPVTGD
                     EIRLLDTAGQEADAGTVGEVVTRGPSLVRGYLGAADDSAFTADGWYHTGDLARRRADGR
                     IDIAGRIKDLVNR"
     CDS_motif       complement(6192..6257)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AWN90_RS33370_0005"
                     /evalue="4.80E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="AWN90_RS33370"
                     /protein_end="388"
                     /protein_start="366"
                     /score="19.0"
                     /tool="antismash"
                     /translation="GTVGEVVTRGPSLVRGYLGAAD"
     CDS_motif       complement(6441..6473)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AWN90_RS33370_0004"
                     /evalue="9.20E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="AWN90_RS33370"
                     /protein_end="305"
                     /protein_start="294"
                     /score="-2.2"
                     /tool="antismash"
                     /translation="LQLGGAVTPPD"
     CDS_motif       complement(6627..6659)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AWN90_RS33370_0003"
                     /evalue="2.80E+00"
                     /label="NRPS-A_a2"
                     /locus_tag="AWN90_RS33370"
                     /protein_end="243"
                     /protein_start="232"
                     /score="2.3"
                     /tool="antismash"
                     /translation="LGVLDAGGTVV"
     CDS_motif       complement(6777..6836)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AWN90_RS33370_0002"
                     /evalue="2.90E-03"
                     /label="NRPS-A_a3"
                     /locus_tag="AWN90_RS33370"
                     /protein_end="193"
                     /protein_start="173"
                     /score="10.8"
                     /tool="antismash"
                     /translation="AVILLSGGTTGRPKLVPHTH"
     CDS_motif       complement(7101..7136)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AWN90_RS33370_0001"
                     /evalue="2.20E-01"
                     /label="NRPS-A_a2"
                     /locus_tag="AWN90_RS33370"
                     /protein_end="85"
                     /protein_start="73"
                     /score="5.6"
                     /tool="antismash"
                     /translation="LAVQRAGAAAIP"
     gene            complement(7538..8746)
                     /locus_tag="AWN90_RS33375"
                     /old_locus_tag="AWN90_33400"
     CDS             complement(7538..8746)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="AWN90_RS33375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33400"
                     /product="cytochrome P450"
                     /protein_id="WP_082871579.1"
                     /sec_met_domain="p450 (E-value: 3.5e-21, bitscore: 73.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTEEHAWRLPVVRDGAYDLPAVCRSMQQAGPIVPARTPNGKTVW
                     VVTRHAEVRRVLADSRTTADRAHPNFPSFEQSADAPVLISGPNPFLVSMDPPAHTRARG
                     DLKREFEERRIRDYAPVVEKIIAEAVGQLRAGPRPVDLVAEFALRVPSRVICELLGVPY
                     ADHDFFESRTPALIDNTVTPEQGRAAFGEIHEYLTGLVAAQEADPGDDIIGNYVRATRE
                     RGDYRREALVSHAFLLLIAGHETTANQIALSALALMQRPELREHLDGDPVRMASAVDEM
                     LRYFTIVDTVSRVATADIEIGGVTIRAGDGIVALCTIANRDPDVYADPDELDLTRGSRR
                     HLAFGFGPHQCLGQGLARLELELALRTLVTELPGMRLAVPATELEFKGTTSAFGVRRLP
                     VTW"
     gene            complement(8740..10008)
                     /locus_tag="AWN90_RS33380"
                     /old_locus_tag="AWN90_33405"
     CDS             complement(8740..10008)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013646.4"
                     /locus_tag="AWN90_RS33380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33405"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_067591017.1"
                     /transl_table=11
                     /translation="MASGTDADAVVCGAGAGGLAAACALAAAGLAVIVLDKQRQPPSIA
                     KGELLQPGSLTALDRWGVTRRLLAAGGVEIDRLCARASDGRALLELDYPGLLGGRRRIL
                     SADYPTILAALADSLPPGVRVHRGVPVRGPLHDDTGRVCGVEVADERLGSVRAPLVVAA
                     DGAASGLRAAAGIAVARTQYPHRLVSFDVPGARDEELTAYVTDRGLRLVYPLPHARTRL
                     YIQAGPQELRGRDDAAMRRWAVEATAGIAALAPLAELLLDPRTQRQLFSVPRYLVDRLA
                     LPGLALVGESAHAVHPMAAQGMNSAIADAAELADRITAVGAADPAALDRALTDYERVRL
                     PQLRHVATVSHNASRMLTAVSPVGRRLGRRLLRGTANNPRLLAATCRNIAGVNPAPLGM
                     VDRLYQLGLLPAQRGRDIEEAMC"
     gene            complement(10001..11671)
                     /locus_tag="AWN90_RS33385"
                     /old_locus_tag="AWN90_33410"
     CDS             complement(10001..11671)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.4"
                     /locus_tag="AWN90_RS33385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33410"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_067591021.1"
                     /sec_met_domain="T2TS (E-value: 3.6e-43, bitscore: 145.9,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTRTIDTALETGAEAVLRHRAADGLFDYDSGVGATLATAGATLV
                     LHLHDPVGSRAYVTGGVAHLSRTQNGDGGWGSVPGQPTEAVTTAIAAAVLHLVDADGSG
                     DRVRAGRAALDRLGGLSGIADPALSAVCHRFHAMAGWAPPAPVRVPLWVFALPRLRRTR
                     MSFRSGVLAATALAQARAEPGGLLRRLIDHAATPAALRVLYGIHRDEGGTGAFGADAWA
                     AGMTGLGLVRSGAAPDLTEAIADFLRRSVFADGSWTIVEIRLTYTGFAATGLCDAGYGA
                     DPRLAVTADGVRAAQLTRPFTMLDCPPGGWSYSGPDGWPVTLESAELLSALAKMPGADR
                     DPHVARGARWLAGRQDTRGSWSLWVRDTALANDGPCPYLTAQAVDALLDAGIPPEDNGI
                     RRAARWLAGVQRPDGSFESLWYRGHTAGTAQVIGALARITDPATDPTVRGGVRWLLATQ
                     HSDGSWGPGDGRAGSVEETAWALRALLEAGIAPGTAEIDRAADWLLARQQPDGHWPEAP
                     VSAYIRHCVHYPNGAITAGLALRALAAYRRGLGRKDDDG"
     gene            complement(11668..12636)
                     /locus_tag="AWN90_RS33390"
                     /old_locus_tag="AWN90_33415"
     CDS             complement(11668..12636)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013226.4"
                     /locus_tag="AWN90_RS33390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33415"
                     /product="UbiA family prenyltransferase"
                     /protein_id="WP_197696564.1"
                     /transl_table=11
                     /translation="MSARTRRHWWAHVETCRPYTLAYPGLAGLAGAALGGHPAPAQWMT
                     AWLAPTLVWAAGLYLGDYLDRELDAGSKPHRPIPSGRLRPGTAVAVGAGCVAVALAVTA
                     LVQAWAVAVAVLGAVGVVVYSKVLKPRGIFGNLARGLLTGLVLLFAATVVDGHPVALAW
                     AWACVFLVQDTASNLVGTVRDTAGDRAGGYRTLPVVIGARAASWCAAALFAAAMAAAVA
                     LAVIGGLGAVGGGLVLAAVCLGLAGYRVLLGGDPADPRRALRTHEILIAERLVLAAAVA
                     SGGLGAPVAVVILVAALAISLSTQALLRRRHEFGDIPVRSA"
     gene            complement(12633..13631)
                     /locus_tag="AWN90_RS33395"
                     /old_locus_tag="AWN90_33420"
     CDS             complement(12633..13631)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="AWN90_RS33395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33420"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_067591025.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7.2e-57, bitscore:
                     190.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPGYIDSRTEEFDPAPALRHYLAGTAAGDGDRLDAVTRYAVQPP
                     GKLVRPVLLVESAAAVGADPADLVPIAVALEYLHVATLVHDDIIDGDLLRRGRPTVHAR
                     YGRDEAIVAGDALLLDTFRTLTEAAELGFPPAAVLEAVRIVAVAGLDLCRGQAMEAGLA
                     GDLYCGMARYRTMAGLKTGALFIAACAAGAVLGGGSGEEVRALRSFADHLGCAFQMRDD
                     LLPYLADTSRAGKSSVTDIVNQRPTFPVLVGIELADTTQCWRIEQSLSGRLPADEAHRL
                     LRQVLTETGALAEASARVAAEVAAARADLAPFGVRGERLIALADSMIGRTW"
     gene            complement(13628..14656)
                     /locus_tag="AWN90_RS33400"
                     /old_locus_tag="AWN90_33425"
     CDS             complement(13628..14656)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (30-327). E-value: 1e-45.
                     Score: 148.4. Matches aSDomain:
                     nrpspksdomains_AWN90_RS33400_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012382.4"
                     /locus_tag="AWN90_RS33400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33425"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_082871581.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 7.9e-44, bitscore:
                     148.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVNSGEWVDDPDLSMNTVAFRPDRQLVARAAEAAAIANDYPDMTA
                     AGATAALAEHLGLPADHLVFGPGSAALCQLLLLVCCEPGAQVVHQWPSFEGYPSMIGHV
                     RADAVPVALDGVDTDLDAMAAAVTDRTAVVMLCNPNNPTGALLDQQRLRRFLDRLPDHV
                     TVLIDEAYRDFVLDPGYRDALDLVREDPRVCVLRTFSKSYRLAGLRIGYLVAQPALTAR
                     LAVLRMFFAPSAPAQAAAVAALAGVAEMRQRCAQVGAERTRLRDLLIEQGWQVPVSQAN
                     FLWVPTPDAGEFTRHCAAYGLRVREWAERGVRVTIGSPATNDAFAEVAAGFRAAARQAV
                     AP"
     aSDomain        complement(13676..14566)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AWN90_RS33400_Aminotran_1_2.1"
                     /evalue="1.00E-45"
                     /label="AWN90_RS33400_Aminotran_1_2.1"
                     /locus_tag="AWN90_RS33400"
                     /protein_end="327"
                     /protein_start="30"
                     /score="148.4"
                     /tool="antismash"
                     /translation="AEAAAIANDYPDMTAAGATAALAEHLGLPADHLVFGPGSAALCQL
                     LLLVCCEPGAQVVHQWPSFEGYPSMIGHVRADAVPVALDGVDTDLDAMAAAVTDRTAVV
                     MLCNPNNPTGALLDQQRLRRFLDRLPDHVTVLIDEAYRDFVLDPGYRDALDLVREDPRV
                     CVLRTFSKSYRLAGLRIGYLVAQPALTARLAVLRMFFAPSAPAQAAAVAALAGVAEMRQ
                     RCAQVGAERTRLRDLLIEQGWQVPVSQANFLWVPTPDAGEFTRHCAAYGLRVREWAERG
                     VRVTIGSPATNDAFAE"
     misc_feature    14675..14688
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.35"
                     /tool="antismash"
     misc_feature    14792..14812
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.39"
                     /tool="antismash"
     misc_feature    14823..14836
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.33"
                     /tool="antismash"
     misc_feature    14823..14840
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.21"
                     /tool="antismash"
     misc_feature    complement(14824..14837)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.99"
                     /tool="antismash"
     misc_feature    14825..14839
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.81"
                     /tool="antismash"
     misc_feature    14848..14868
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 22.13"
                     /tool="antismash"
     misc_feature    14854..14867
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.82"
                     /tool="antismash"
     misc_feature    complement(14855..14868)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.41"
                     /tool="antismash"
     misc_feature    complement(14857..14870)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.76"
                     /tool="antismash"
     misc_feature    complement(14869..14886)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            14954..15808
                     /locus_tag="AWN90_RS33405"
                     /old_locus_tag="AWN90_33430"
     CDS             14954..15808
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (6-248). E-value: 1.6e-61. Score:
                     200.3. Matches aSDomain:
                     nrpspksdomains_AWN90_RS33405_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1121: dioxygenase, TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014698.4"
                     /locus_tag="AWN90_RS33405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33430"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_067591028.1"
                     /sec_met_domain="TauD (E-value: 1.2e-59, bitscore: 200.3,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPATITVQPISGALGAELRGIDLATLTDTEFETVHELLLEYQVLF
                     FPDQGDLPPAAHIAFGRRFGEVELHPYLPKLEGFPEIVLIESDRGGKVDCWHTDMTFHE
                     SPPLVSILQLTTCPPRGGDTMWTNQYLVYERLSAPLRDLVDGLTAVHSVTAGDYTASAE
                     HPLVRVHPETGRRSLYVNRLFTSHIPQLSRPESDALLQHLVEFSEGPQFTCRFRWQPGA
                     VALWDNRVTQHYAVNDYDEPRRGRRVTVLGDHPEGNPPRWPNYTPADGERYWPMRVNAK
                     SGY"
     aSDomain        14972..15697
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AWN90_RS33405_TauD.1"
                     /evalue="1.60E-61"
                     /label="AWN90_RS33405_TauD.1"
                     /locus_tag="AWN90_RS33405"
                     /protein_end="248"
                     /protein_start="6"
                     /score="200.3"
                     /tool="antismash"
                     /translation="VQPISGALGAELRGIDLATLTDTEFETVHELLLEYQVLFFPDQGD
                     LPPAAHIAFGRRFGEVELHPYLPKLEGFPEIVLIESDRGGKVDCWHTDMTFHESPPLVS
                     ILQLTTCPPRGGDTMWTNQYLVYERLSAPLRDLVDGLTAVHSVTAGDYTASAEHPLVRV
                     HPETGRRSLYVNRLFTSHIPQLSRPESDALLQHLVEFSEGPQFTCRFRWQPGAVALWDN
                     RVTQHYAVNDYDEPRRGRRV"
     gene            complement(16057..16788)
                     /locus_tag="AWN90_RS33410"
                     /old_locus_tag="AWN90_33435"
     CDS             complement(16057..16788)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024881.4"
                     /locus_tag="AWN90_RS33410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33435"
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="WP_156674584.1"
                     /transl_table=11
                     /translation="MRCETVREALSARIDGEPEPIRAAVVDRHVVGCAGCRDWYRRAEE
                     LRRATILHPAPAVPDLTARIMAAVPEQTREPVGLRAALAVVAVAQTSLALAQLFGADTG
                     MGHAAHGAFMMGHMSHESAAWNLAIGIGLVWAALRTRTAAGQLPMLSVFVGVLTGVSLL
                     DITRGDVTAARLISHVPVLLGVALLYLVYRRHRDDDRPIGDRMDTGRERFADEVPDIDV
                     AHEDSILRFRHRRPASRHRAA"
     gene            16873..17439
                     /locus_tag="AWN90_RS33415"
                     /old_locus_tag="AWN90_33440"
     CDS             16873..17439
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003879988.1"
                     /locus_tag="AWN90_RS33415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33440"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_067591031.1"
                     /transl_table=11
                     /translation="MPGDKDDELTALALAAGRGDRRAFEQWVRAMQADVWRFHAYRAGP
                     GAADDLTQETFVRAYGSLPRFAGRASARAWLLSIARRVVVDSIRSAVARPRLHDTDDWE
                     SAAEQRAAVQRTGRTFEDLVEIRMLLDGLDPERREALILTQVLGLSYQEAAEVCGCPVG
                     TVRSRIARAREDLLAATRERDGGVG"
     misc_feature    complement(16880..16895)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.91"
                     /tool="antismash"
     misc_feature    complement(17454..17471)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.82"
                     /tool="antismash"
     misc_feature    complement(17481..17499)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.83"
                     /tool="antismash"
     gene            17491..17829
                     /locus_tag="AWN90_RS33420"
                     /old_locus_tag="AWN90_33445"
     CDS             17491..17829
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011209619.1"
                     /locus_tag="AWN90_RS33420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33445"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_067591034.1"
                     /transl_table=11
                     /translation="MTVAFDVLVEPNRRRILDLLLQRPQSVGELATRLGLSQPGTSKHL
                     RVLREAGFVRVRVDAQRRWYELDPAPLAELDAWLAPYRRLWADSLDTLERHLDAPPEPA
                     NPERGETS"
     gene            17826..18731
                     /locus_tag="AWN90_RS33425"
                     /old_locus_tag="AWN90_33450"
     CDS             17826..18731
                     /GO_function="GO:0005488 - binding [Evidence IEA]"
                     /NRPS_PKS="Domain: Polyketide_cyc2 (16-135). E-value:
                     4.9e-13. Score: 41.6. Matches aSDomain:
                     nrpspksdomains_AWN90_RS33425_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019928.4"
                     /locus_tag="AWN90_RS33425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33450"
                     /product="SRPBCC family protein"
                     /protein_id="WP_067591037.1"
                     /transl_table=11
                     /translation="MSRTGTLRRDGDRWELRFERELAHPVETVWRAVFDSDRLAHWYPA
                     AERELEPVVGGKVREVYGAGEQAVTIHGVVTALEPPHVLEYRMDSSAVGLAGFDEIRTL
                     RFELHPLPTGCRLVFLHTFGDRPGAASFATGWHRCLDALADSRTDAPTSADPDFSWPQQ
                     HERYVRQFGLDEGTAEQTDTATIIRFERQLMMHPVDEVWQALTAGHTPTAGAEPPAPFA
                     PAGLPTGPARTVDPPSLLEFHTATTNPHTIRWQLRPGPGGARITLTDTAPQLTPEETAE
                     ALATWHDHIEQIVADLGRQD"
     aSDomain        17874..18230
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AWN90_RS33425_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="4.90E-13"
                     /label="AWN90_RS33425_Polyketide_cyc2.1"
                     /locus_tag="AWN90_RS33425"
                     /protein_end="135"
                     /protein_start="16"
                     /score="41.6"
                     /tool="antismash"
                     /translation="RFERELAHPVETVWRAVFDSDRLAHWYPAAERELEPVVGGKVREV
                     YGAGEQAVTIHGVVTALEPPHVLEYRMDSSAVGLAGFDEIRTLRFELHPLPTGCRLVFL
                     HTFGDRPGAASFATG"
     gene            complement(18767..18997)
                     /locus_tag="AWN90_RS46315"
     CDS             complement(18767..18997)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS46315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_156674585.1"
                     /transl_table=11
                     /translation="MLFIDEVGGVRTQETLRPPGAPTGDTGKAQTVWTPDRAGVHTIWA
                     GEYPTPGAAIVTSEVNVGTGINLGPACLVLP"
     gene            complement(19436..19873)
                     /locus_tag="AWN90_RS33435"
                     /old_locus_tag="AWN90_33460"
     CDS             complement(19436..19873)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020950.4"
                     /locus_tag="AWN90_RS33435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33460"
                     /product="protease inhibitor I42 family protein"
                     /protein_id="WP_156674586.1"
                     /transl_table=11
                     /translation="MRTPLLMVAFGVALAAGGTNAVAWADPAAGPAVATPISEPMIVGT
                     DADGQTVTLTVGQELAIALPDNPSTGYRWQLADFDQGVMHQEGDPQFRPTNIMPGSPGT
                     SVWTFTASAPGNTRLDLVSLPPAWQPGTPPPQHFSVNASVH"
     misc_feature    19839..19854
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.61"
                     /tool="antismash"
     gene            complement(19990..20796)
                     /locus_tag="AWN90_RS33440"
                     /old_locus_tag="AWN90_33465"
     CDS             complement(19990..20796)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014982469.1"
                     /locus_tag="AWN90_RS33440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33465"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_067591046.1"
                     /transl_table=11
                     /translation="MTRPDWAPEGIDLDRPSASRVYDYFVGGMHNFEIDRALARQIEAF
                     TPNVAETMRANRDLLRRCVRLLVDAGIDQFLDLGSGIPTVGNVHEVAQARNPGASVVYV
                     DIDPVAVAHSRAILADNPGATVIQADVAEPEAILAEAAATGLLDFRRPMAVLLLGVLHF
                     VPEGADPAASVARLREAVAPGSYLAITHATADGQPAEVLAAQKLSGRTSTEIVLRSREQ
                     IGAYFADWTLLAPGLVPLPLWRPDDPADVGECPEMSGAYGGVARKY"
     misc_feature    20841..20852
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.22"
                     /tool="antismash"
     gene            20914..23031
                     /locus_tag="AWN90_RS33445"
                     /old_locus_tag="AWN90_33470"
     CDS             20914..23031
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014982468.1"
                     /locus_tag="AWN90_RS33445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_33470"
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="WP_082871892.1"
                     /transl_table=11
                     /translation="MAWDGSDLDGPHAELAERWAAALGGGARDHVVPLSASETRELLTR
                     LAADLVTATHTGDPARAAELGAELARAHFVGDEVLGRSIAVLERYFADTGAPCPAAVLG
                     AFASGYVRAFRAWLLAEQESVRAADIAARRVVEQQLRGSEARLRAVFSQAGIGTGLSDM
                     SGRIIEVNTAFATMLGYRPEEMTRFTVTDLAHPDDPPGMWELYAGVLRGEHDSVQLEKA
                     YRHRDGHTVWTNINVSLIRDEQGLPQYTLVLVEDISERRALRERLTYRALHDPLTGLAN
                     RSRFFDALTTAFADPTARVGLCYVDLDHFKTVNDTLGHAVGDVLLTQAAARLTACACGP
                     DQLVARMGGDEFIILVPRARNSGELAELARTVVDAFSVPFDILGHRLTVTASVGVMIER
                     TAHTTTDELLQAADTTMYWAKTDGRARYSIFDPDRRRREHTRAELTAAMPAALARGEFY
                     LDYQPIVALADQRPLAVEALVRWRHPALGVLSPARFVDLAEDSGHIAALGTVVLEQACR
                     DGRRWHDEFGAHTPVVSVNVSAAEVADPAWLHRVQRIITDTGFDPARLQLELTERTFMH
                     ATGRPLQALRTLAEAGVRIAIDDFGTGYSNLAYLGRLPLHVVKLAGPFIHRIRSAGTAD
                     RSDLLILETIIGLTHGLGLTVTAECVETGHQADRLLDLGCDTAQGWLFHRPMPADRITA
                     LLTAACVHPAE"
     misc_feature    23080..23096
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.59"
                     /tool="antismash"
     misc_feature    complement(23132..23146)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.04"
                     /tool="antismash"
ORIGIN
        1 cgcggtggag cgattcctgg tctccgccga ggccgcccgc gcgtccgggc ggctggatct
       61 ggccgccgac agcatccgcg ccgggctgcg attatggcgc ggggaggcgc tgtccggggt
      121 tccggggccg tgggcggcgg gtgagcgggc gcggctgcat cgctcgcgag agacgctgcg
      181 ccgctgggcc atcgagatct ccatcgatca gggcaatcac gaggcggcga tcgcgcagct
      241 ggaggccctg gtgcatgccg agccgcagtc cgagcagtgg cgaatcctgt tgatgacggc
      301 gctgtttcgg gccgggcggc gcatcgacgc cctcgaggtc taccgggccg cgcgcgactg
      361 gttcatcgac accatgggtt tggagcccag tcccgccatg accgaactgc accaacacat
      421 cctgagcggc gagacggtgg gcggtggcgc cctcgccccg gccgcggtgt cggctccggc
      481 gcggccggtg ccgtcgcagt tgccgccgga caccatcgac ttcaccggcc gcaccgccga
      541 actcgcgcag gtgaccgcgg cgctcgcccc gggccgcgcg gtctcggtgg tggccctcac
      601 cggcatgggc ggggtgggca agacggcgct ggcggtgcat gtcgggcatc gggtgcagga
      661 ccggtttccc gacggccgcc tgtacgtcga tctgcggccc gccgacgggc cgcccgatgt
      721 ggccgaggtg ctggcgggtt tcctgcgcgc cctgggtgtc gccgaggccg agatcccggc
      781 gggcggcgcg gagcggtcgg ccctgtttcg gaccgtcgcc cgcggcaaac gcctgctggt
      841 gctgctcgac aacgccatct gcaccgaaca ggtgacgccg ctgctgcccg cgtcggccgg
      901 atgcgcggtg ctggtcacgg cccgcacgcc gatgacggcg ctgccggtgg cgcggcgggt
      961 gcggctggcg ccgatggagc ccgccgaggc cgccgagctg ttcacccgga tcgtcgccga
     1021 cgcccgcccg gccgcggaac cgcaggcggt gcgccgcgtc gtcgtcctgt gcggcggcct
     1081 gccgctggcg atccggatca tcgccgcgcg cctggtgacc cggccgggct ggatgatcgc
     1141 cgacgaggcc gaccggctgg gcgccgagcg ggacggcctg cagcagttcc ggtttcgcga
     1201 cacctcgctg gagagcgcct tccaatcggc ctacgaccag ctggatcccg aactggcgca
     1261 cgcgtttcgg acgctggccc ggctggaccg cccggacgcg accgtggcgg cggtcgcggc
     1321 cgcgctcggc tgcgatccgg gcgaggcggt gcgcctgtgc gacgccctgg tcgatcgcgg
     1381 catgctggac agcccggcgc ccgggcgcta ccgcttccac gatctggtgc gggtattcgc
     1441 ccgcagcaga ccggattccg acgcatcggc cgcgatgcgc cgcccgaccg ggttcatcgg
     1501 ggcgccgagc ccggtgatcc tgccgtgcac gcagtgttcc ggatagctca gcgcgggcgg
     1561 cagtcgatga cggtgagccc gccgtcccag cgccgcaccc cggccaccgt cgcaccggcg
     1621 cgggcggcga gggcggtgaa ctggtcggcg tcgcgcagcc gcccgccgac cacggcgagc
     1681 atctgtaggt cgtagggcga atcgggggcg agcacgctgt cgtcgggcag cacctccacg
     1741 atcagcaccc ggccgccggg ccgggcggcc gccacgcagt tgcgcagaat gtcgtgcgcc
     1801 gcttggtcgt tccaatcggt cagcacgcgg gacacgatgt aggcgtcggc gccggcgggc
     1861 agcggctcga agaagctgcc gccgatcgcg tcggcgcggg cgccgagccc ggcggcggcg
     1921 aaccgctgcc gcgcggtgtc gaccgcgcgc ggcagatcca cgaccgtgcc gcgcatgctc
     1981 ggccgggcac gcaggatctc ggtgagcagg atgcccgcgc cgccgccgac gtcgatcacg
     2041 tgctcgatgc cggtccagtc gtactcggtg gccaccaggt gcgccacggt ggcggtgtcg
     2101 gtgcccatga gggtgtcgaa ttcggcacgc agccgcggtt tgtcggccag gtcctcccac
     2161 agcgggcggc cgtgcaccgc gctgtagccg tcgccgccgg tgcgcagcgc gtgcgccagg
     2221 ccgccgtagg cggcgtccat gcgcgcaccg gggccggaca ggtccatcca ggcgcgccgc
     2281 gcggcgcccg cctcgccgat caggccgcgc gagacgtcgg tgagggcgta gcgctgcggt
     2341 tcgggctcgc cgaacaggcc gtgcgccacc aggtaccgca gcagtcggcc cagcgtgtcg
     2401 gcgtcgacgc cggtggccgc cgccagctcg cccagcgacg ccgggccgtc ggcgagcagc
     2461 tccggcacgc cgagggtgac cgcggcgcgc accgcgtagg gcgtggccac gtcggtgagc
     2521 cgggccagga tcgcgtcggg atcggttgcc acgtcgggca tctgcacact cctcgctcgg
     2581 ggatgggttg tcatcgcgac cgcgcgacca gcgcggccag gtggggccgg gtatcggtga
     2641 aatggccgag gcggccgagc gcaccgtcga cgaccccggc ggccagggcg agcagcttgc
     2701 tcgtccggtc gcgctcgaac aggccgatgg acagcacgtt cgagatcagg tgggcattga
     2761 gccgcagcaa ctcggcccgg tggcgggcat tgcgggtggt gaagtgcacg cagttgcggg
     2821 cggtgtagta gcgccggaac ggcggatagt ggaaggccag catggatctg ccgagcagcg
     2881 accggatctc gaacgcgccg acgctgtgcc gcagcaccac accggtattc accacgacgc
     2941 gcacgccgcg ccgggtcgcg cgcaggcaca ggtcccagtc caggtagtcg atgatgtagc
     3001 gctcgtcgaa cgggcccatg gcctgccacg cgtcccgggt gatcatggtg cccgacgaga
     3061 tcacgaaggg cgcctccagc gggccgttct tcgcgtgcgc ggcaatggtg tcggcgtcga
     3121 ccacctcgtt gccgagcagg aatatgccgg tgccgcggtc gtagatcacc ggaccggcca
     3181 gcagcggggc cgacccttcg ggccggggtg tggcgagcat ggcgtcgaag tagtcgtcgc
     3241 cgggttcgga gtcctggtcg aacaggaaga agacctcggc gccgcgcccg gcgagcaggt
     3301 cgatgccgcg gttgaagccg ccgccgaggc cgccctcgtt cccgttgtgc agcaccgtga
     3361 ttcccgcgtc ggtgaggcgc gcgtaccagg gttggggcac gggggtgttg tcgaccacgc
     3421 acacctggat gccgcgccgc gccagcgata tcgcgtgctc gacattgccg ggcgtgggat
     3481 tccaggtgac gatcaccacg ccgaaggccg ggccggtcat cggctcacct ccgtcagttc
     3541 ggcgcggatg gcatcgagga cggcgtcggt gccgaggtgg tcgccgacgt agccgatggt
     3601 catgcgcccg gcgtaggtgt agacctgcag cagcgcggcc ggggaatcgg cggccgaggg
     3661 gcgcgggtgg gcgaggtgga atccggtctc gtagtcggtg accgtcagcc cggcgggcgt
     3721 gcgcagcgcg gggatcgcgc ccagattggt gagcgagatg tgcccggcca gactgtgttt
     3781 gcgggtgtcg ccgaacagat ccgggaagtg cagcaccgac tgggcgacca cgccgctgtc
     3841 caggtcggtg cgcaaccggt cgccgatgcg gcgggcgaga tcggtggcgg cggtggcggt
     3901 ttcgatctcg gcgtcgaagc aggcgaaggt cgacatggtg gtgccgccgg tcgccgacac
     3961 cgcgggcagc agccgcgacc gcagatccac cgccgccaac acgcccaccg gcaccgggct
     4021 gccgtccgtc gacgccacgg tggcgtaggc gcgcagcagg gcggcgctga ccaggctgtt
     4081 gaccgacagc ccggtgcggc ggccggattc gactatgccg gtggtgatct cggcgtcgag
     4141 gatcaggcgg tcggggcggg ccaggatatt gcggtagggg atctcgccga cggtctccgg
     4201 ctcgtcgggc atgggccggt agaccggttc cagacccgag cggggcccgc gctcgatgcc
     4261 gcgcgtggtc acgtgccact ccagcgactg cggatagtcc tgcggcgcag gcagatcggc
     4321 gaccgaggcc ggatggcccg cgtacaggtc ccacagccgc gcgaacagtt ccatgtcgtg
     4381 gcgggcgtcg gcgatgctgt gatgcacgaa cagcgtgacc cgcgccccgt cccggccgca
     4441 cacgatatcc aggtacgcca gttgccgatc cggatcggtg aatccggccg gggcccgcac
     4501 cggttccgga tcaccggcgc gcacccaggc gccctcggcg ggaaactcgg tgggccgcac
     4561 cagccgatcg ccgtcctcga gggtgacgat ccggcagccc aggaccgggt aggcgtgctg
     4621 gagggcggtg aacgccgccc gcatcgcgtc cggatcgaag tcccccgtca ccgggacggt
     4681 ccagtagccg aagacaccgc tggacacgaa ccgtcgctcc gacggggaca gtggccgaat
     4741 tatcgtctgc tccatcactt ttcgtccctc atgccacggc ctcgatctcg accagcaggt
     4801 ccctgcggca gatgtcgacg accaggtacg cgatctcggc ctccggcggc agcgcggcgg
     4861 cgcaggcccg gcgcaccacc tccaggtgct cgcggtggcg gacgtacacc ttggcgcgcc
     4921 gaatcgccga cagcccatag ggtttggcga tcccgtaccg gcccagattc tgctcgccga
     4981 ccagttcccg gatattggcg agcgccacct cgcactgccg cgccacatcg cccgggcaca
     5041 ccgtctcgtg cccgaggatc gcggcggtgc ccgagacgaa cagggtgtcg ctgccgccgt
     5101 cgggcagcag gtgggtcgcc cgcgcgaagg tcggcgcctt cggaccgtag cggcgcggat
     5161 accggtaggc cgggatctgg cgcgggttct cgatgtgggt gacgccgccg gaccggcagc
     5221 tcaggaagta gaagaccacg ccgctgccgt gcgtgccgac accggtcgcg gcgggcatcg
     5281 ccttcccgtg tgcggcaaag gcttccgccc gtcccaggca gaagtcgcgg tagatctcca
     5341 ggccgtcggc attggccgcg ttgatgtcgc cgacgtagtt ccacatccgg accagcgtgg
     5401 ggtagccgag cgcgtcggcg aggccgaagg cggccgcgta ccgctcgcgg gtgtgtgccg
     5461 cgtaccggtc gccgtgccga atgtgcccgg cgcagaacag gatatcgtcg tcgtgcgcgt
     5521 agaccaggcc gtcggtgtgg ccggtccgcg cgtcgccgtc ggtgatccac acctcgcgga
     5581 aacccgcgga ttcggttgcg gcggcgcgga tccggaccac cgggacgccg tcgcgcagct
     5641 ccgcggggcc ctcctcggcg ccgaattcca cgacggccag ggcgcgccgc ccggtcaccg
     5701 ccgtcgcggc attctcgtaa tcacagctca gcgccgaccg taccgcacgc acgaacacca
     5761 tccttcgcat tgtcgttcgc ggcggatcgc gccgccgtca accggtcccg cagcgtcggg
     5821 cgatccacct tgcccatgcc ggtccgcggg atgtcgtcca cgacgaacag tgcgtcgggc
     5881 gtcttgtgcg cggcaacgcc ggtgtcggcg aagaacttcc ggacccgtgg gagatccacc
     5941 gcggtcccgg cggcgggaac gacggcggcc gcgatgcatt cgccgaggtc cgggtgcggc
     6001 agcgacacca ccgccgcggc cgcgatcccg ggcagcccgt acagcaccgt ctcgacctcc
     6061 accaccgaga tcttctcgcc gccgcgattg acgagatcct tgatgcgccc ggcgatgtcg
     6121 atccgaccgt ccgcgcggcg gcgggccaga tcaccggtgt ggtaccagcc gtcggcggtg
     6181 aacgcgctgt cgtcggcggc gccgagatag ccgcgcacca gcgacggtcc gcgggtcacc
     6241 acctccccga ccgttcccgc gtcggcctcc tgcccggcgg tgtcgagcag gcggatctcg
     6301 tcgccggtga ccggcaatcc ctgggtgtgg taccggaatt cgggcggatc gtccggcgag
     6361 gtcatgcaca ccggcccctc cgacatcccg tacacctgct gcacggtgac cccgagggcc
     6421 ccttccacct cggcggcgag gtcgggcggc gtgaccgcgc caccgagttg cagcaggcgc
     6481 agaccggcca ccgcggcgcg ggcggcgggc gaggaccggg catgctcggc ccagcgccgg
     6541 gccacggccg ggaccagggc cgacatcgtc accccgtgcc gggcgatcgc cgcgaacgcg
     6601 gcctcgggac tgggcgagcg gcccagcacc acggtgcccc cggcgtcgag cacgccgagg
     6661 atgcccggcg aggccagcga aaagttgtgt gcgacaggca atgccgccag atacaccgtc
     6721 gccgcgtcca ccccgctcgc ggccgcgcac gcccggaagg cgtgccggta gtcgcgatgg
     6781 gtgtgcggca ccagcttggg acggccggtg gtgccgcccg acagcaggat caccgcgtcc
     6841 tcgtcgacgt ccgggtcgtg ccggtccagg tcggcgcgca cccggtccgc ctcctcgacc
     6901 cggtgctcgc acgcgcggcg cagatcgata tcggcggcgc ccacgtcctc ccccgccacg
     6961 aacaccggcc gcccggcggc cagccgatgc gcatcgccgc gatgatcgtg cccctgatgg
     7021 gtgtcgacgg tgaaaacggc cgccacaccg gcggtctcgg cgatccgcgt cagatcgtgc
     7081 agccgatgcc ccatgagcgc cggaatcgcc gccgccccgg cccgctgcac cgccagcatc
     7141 cccaccacca gctcccaccc gttgggcagc tgcatcagca cccgatcccc ccgcccgatc
     7201 cccacctccc gcaacaccac cgccagcgca tcggcccgcc gcgccagcgc cgcgtaactc
     7261 accgcaccgg cgtcgtccca cagcgcgacc cgatccccgc cgcgccgcgc ccactcccac
     7321 atcgccccac ccagcgaccc gctgctcaat cccaccacag cagtcccttc acttccgtcg
     7381 accctccgat gtgctcccgg ctgccctctg cttcgctccc gacacgcgcc ctctgcttcg
     7441 ttccggcgcg caccctctgc tttgttccag cacgcaccct ccgatttgtt ccagcacgcg
     7501 ccctccgatt tgttcccggc atgcttttgg ccgggaccta ccacgtcacc ggaagccgac
     7561 gaaccccgaa agccgaagtg gtgcccttga attccaattc cgtcgccgga accgccagcc
     7621 gcatgcccgg cagctcggtg accagggtgc gcagggccag ttccagttcc aggcgggcca
     7681 ggccctggcc gaggcactgg tgcgggccga agccgaaggc caggtgcctg cggctgccac
     7741 gggtgagatc cagctcgtcg gggtcggcat acacgtcggg gtcgcggttg gcgatcgtgc
     7801 acagggccac gatcccgtcc ccggcgcgaa tggtgacccc gccgatctcg atatcggcgg
     7861 tggccacccg cgacacggtg tccacgatgg tgaaataccg cagcatctcg tccaccgcgc
     7921 tcgccatccg gacggggtcg ccgtcgagat gctcgcgcag ctccgggcgc tgcatcaggg
     7981 ccagcgcgct cagcgcgatc tgattcgcgg tggtctcgtg ccccgcgatc agcagcagga
     8041 acgcatgcga caccagggct tcgcgccggt agtcgccgcg ttcgcgggtc gcgcgcacat
     8101 agttgccgat gatgtcgtca ccgggatcgg cctcctgcgc ggcgaccagc ccggtgaggt
     8161 actcgtggat ctcgccgaac gcggcccggc cctgttcggg cgtgacggtg ttgtcgatca
     8221 gtgcgggcgt gcgggattcg aagaagtcgt ggtcggcata cggcacgccg agcagttcac
     8281 agatgacccg cgacggcacc cgcagcgcga actccgccac cagatccacc ggccgcggcc
     8341 cggcccgcag ctgccccacg gcctcggcga tgatcttctc caccaccggc gcgtagtcgc
     8401 ggatgcgccg ctcctcgaac tcccgcttca gatcgccgcg cgcccgggtg tgcgcgggcg
     8461 gatccatcga caccagaaac ggattcggcc cggagatcag caccggcgcg tccgcggact
     8521 gctcgaacga cgggaagttc gggtgcgcgc gatcggcggt ggtccgcgaa tccgccagca
     8581 cccggcggac ttccgcgtgc cgggtcacca cccacaccgt cttcccgttc ggggtgcggg
     8641 cgggcacgat cggcccggcc tgctgcatgg accggcagac ggcgggcagg tcgtacgcgc
     8701 cgtcgcgcac caccggcagc cgccaggcgt gctcttcggt cagcacatcg cctcctcgat
     8761 gtcgcggcca cgctgggcgg gcagcaggcc caattggtag agccggtcga ccatgcccag
     8821 cggggcgggg ttcaccccgg cgatattgcg gcaggtcgcc gccagcagcc gcggattgtt
     8881 cgccgtgccg cgcagcagcc gccgcccgag ccggcgcccc accggcgaga ccgcggtgag
     8941 catgcgcgaa gcattgtggc tcacggtggc cacgtgccgc agctgcggca gccggacccg
     9001 ctcgtagtcg gtcagcgccc gatcgagggc ggccgggtcc gccgcgccca ccgcggtgat
     9061 ccggtcggcc agctcggccg cgtcggcgat ggcggagttc atgccctgcg cggccatcgg
     9121 atgcaccgcg tgcgcggact cgcccaccag cgccaggccg ggcagcgcca gccggtccac
     9181 cagataccgt ggcacggaga acaattggcg ctgggtgcgc ggatcgagca gcagctcggc
     9241 gagcggggcc agggccgcga tcccggcggt cgcctcgacc gcccagcgcc gcatggccgc
     9301 gtcgtcgcgg ccgcgcagct cctgcggacc ggcctggatg tagagccggg tgcgcgcgtg
     9361 cggcagcgga tacaccaggc gcagaccgcg atcggtgacg taggcggtca attcctcgtc
     9421 ccgggcgccg ggcacgtcga acgacaccag ccggtgcgga tactgggtgc gggcgacggc
     9481 gatccccgcc gccgcgcgca gtccggaggc cgcgccgtcg gcggccacca ccagcggcgc
     9541 gcgcacgctg ccgagccgct cgtcggccac ctcgactccg cacacccgtc cggtgtcgtc
     9601 gtgcagcggc ccgcgcaccg gcacgccgcg atgcacccgc acgcccggcg gcaggctgtc
     9661 ggccagggcg gcgagaatcg tcgggtagtc ggcggacagg atccgtcggc ggccgccgag
     9721 cagccccgga tagtccagtt ccagcagtgc ccgcccgtcg ctcgcgcggg cgcacagccg
     9781 gtcgatctcc acgccgcccg ccgccagcag ccgtcgagtc actccccacc gatccagcgc
     9841 ggtgagcgaa cccggttgca gcagttcacc cttcgcgatc gacggcggct gtcgctgttt
     9901 gtccaggacg atcaccgcca gcccggccgc cgcgagcgcg caggccgcgg ccaggccgcc
     9961 cgctcccgcg ccgcacacca cggcgtcggc gtcggttcca ctagccatcg tcgtccttcc
    10021 tgccgaggcc gcggcgatag gcggccagcg cgcgcagggc caggcccgcg gtgatcgcgc
    10081 cgttggggta gtgcacgcag tgccggatgt aggcgctgac cggcgcctcg ggccagtgcc
    10141 cgtcgggttg ctgccgggcc agcagccagt ccgcggcgcg gtcgatttcg gctgtgccgg
    10201 gggcgattcc ggcctcgagc agggcgcgca gcgcccacgc ggtctcctcc accgagcccg
    10261 cccggccgtc gccgggaccc cacgatccgt ccgagtgctg ggtcgccagc agccagcgca
    10321 cgccgccgcg cacggtgggg tcggtggccg ggtcggtgat ccgcgccagc gcgccgatca
    10381 cctgcgcggt cccggcggtg tggccgcggt accacagcga ttcgaacgag ccgtcgggcc
    10441 gctgcacccc ggccagccag cgcgccgcgc gccgaatccc gttgtcctcg ggtgggattc
    10501 cggcgtccag cagcgcgtcg acggcctgcg cggtcaggta cgggcacggg ccgtcgttgg
    10561 cgagggcggt gtcgcgcacc cacaggctcc acgagccgcg ggtgtcctgc cgcccggcca
    10621 gccagcgcgc gccccgcgcc acgtgcggat cgcggtccgc gcccggcatt ttcgccagcg
    10681 ccgacagcag ttccgccgat tccagggtga ccggccagcc gtcgggcccg gagtagctcc
    10741 agccgccggg cgggcagtcc agcatggtga acggccgggt cagctgcgcg gcgcgcacgc
    10801 cgtcggcggt caccgccagc cgcggatcgg ccccgtagcc cgcatcgcac aggccggtgg
    10861 ccgcgaaacc ggtgtaggtg agccggattt cgacgatcgt ccaggagccg tcggcgaaga
    10921 cgctgcggcg caggaagtcc gcgatggcct cggtgagatc cggtgcggcg ccggagcgta
    10981 cgagccccaa cccggtcatc ccggccgccc aggcgtcggc gccgaacgcg ccggtgccgc
    11041 cctcgtcgcg atggatgccg tacagcaccc gcagcgcggc gggggtggcg gcgtggtcga
    11101 tcaggcggcg cagcagcccg ccgggttcgg cgcgcgcctg ggcgagcgcg gtggcggcca
    11161 gcaccccgga ccggaacgac atccgggtgc gccgcagccg cggcagcgcg aacacccaca
    11221 gcggcacccg aaccggcgcg ggcggcgccc acccggccat ggcgtgaaaa cggtggcaca
    11281 ccgccgacag cgcggggtcg gcgatgccgg acagcccgcc gagccggtcc agcgcggccc
    11341 gcccggcccg cacgcggtcg ccgctgccgt cggcgtccac caggtgcagc acggcggccg
    11401 cgatggcggt ggtgaccgcc tcggtgggct ggccgggcac cgaaccccag ccgccgtcgc
    11461 cgttctgtgt ccggctcagg tgcgcgaccc cgcccgtcac atacgcgcgg gagccgaccg
    11521 gatcgtgcag gtgcagaacg agagtcgcgc ccgcggtggc cagcgtcgcg ccgaccccgg
    11581 agtcgtagtc gaacagcccg tcggcggcgc ggtggcgcag cacggcctcc gcaccggtct
    11641 cgagcgcggt atcgatcgtg cgggtggtca tgccgacctc acagggatat cgccgaattc
    11701 gtgccggcgc cgcagcagcg cctgcgtgga cagggagatc gccagcgccg caaccagaat
    11761 cacgaccgcg accggcgccc cgaggccgcc ggaggcgacc gcggcggcca gcaccagccg
    11821 ctcggcgatc aggatctcgt gggtgcgcag cgcccgccgc ggatcggccg ggtcgccgcc
    11881 gagcagcacc cggtacccgg ccaggcccag gcagacggcc gcgagcacca gcccgccgcc
    11941 caccgcaccc agcccgccga tgaccgccag cgccacggcc gccgccatgg cggcggcgaa
    12001 aagcgctgcc gcacaccagc tcgcggcccg cgcgccgatc accaccggca gcgtgcggta
    12061 cccgcccgcc cgatccccgg cggtatcgcg cacggtgccg accagattcg acgcggtgtc
    12121 ctgcaccagg aacacgcacg cccacgccca ggcgagcgcg accggatggc cgtccaccac
    12181 ggtcgccgcg aacagcagca ccaggccggt cagcagcccg cgcgccagat tgccgaagat
    12241 gccgcgcggc ttgagcacct tgctgtagac caccacgccg accgcgccca gcaccgccac
    12301 cgcgaccgcc cacgcctgga ccagcgccgt caccgccagc gcgaccgcca cgcagcccgc
    12361 gcccaccgcc accgcggtcc ccgggcgcag ccgccccgac gggatcggcc ggtgcggttt
    12421 gctgcccgcg tccaactcgc ggtcgaggta gtcacccagg tacaggcccg cggcccacac
    12481 cagcgtcggc gccagccacg ccgtcatcca ttgcgcgggt gcgggatgcc cgcccagggc
    12541 cgcgcccgcc aggcccgcca ggccgggata ggccagggtg taggggcggc aggtctccac
    12601 gtgcgcccac cagtgccgcc gggtgcgcgc gctcaccacg tgcgcccgat catgctgtcc
    12661 gccaaggcga tcagccgctc cccgcgcaca ccgaacggcg cgagatccgc acgcgccgcg
    12721 gccacctcgg ccgccacccg cgccgacgcc tcggccagcg cgccggtctc ggtgagcacc
    12781 tgccgcagca gccggtgcgc ctcgtcggcg ggcagccgcc cactcagcga ctgctcgatg
    12841 cgccagcact gcgtcgtgtc ggccagttcg atgccgacca gcaccgggaa cgtcggccgc
    12901 tgattgacga tgtcggtgac cgagctcttg cccgcccggc tggtgtcggc cagatacggc
    12961 agcagatcgt cgcgcatctg gaaggcgcag ccgagatggt cggcgaacga gcgcagcgcg
    13021 cggacctcct cgccgctgcc gccgccgagc accgcgcccg ccgcgcacgc cgcgatgaac
    13081 agcgcaccgg tcttcagccc ggccatggtg cggtagcggg ccatcccgca gtacaggtca
    13141 ccggccaggc ccgcctccat cgcctgcccc cggcacagat ccagtcccgc gaccgcgacg
    13201 atgcgcaccg cctccagcac cgcggccggg gggaacccga gctccgcggc ctcggtcagc
    13261 gtgcgaaagg tgtccagcag caacgcatcc ccggccacga tggcctcgtc gcggccgtag
    13321 cgggcgtgca cggtggggcg gccgcggcgc agcagatcgc cgtcgatgat gtcgtcgtgc
    13381 accagggtgg ccacgtgcag gtactccagc gccaccgcga tcggcaccag gtcggcggga
    13441 tccgcgccga ccgccgccgc cgactccacc agcagcaccg ggcgcaccag cttgcccggc
    13501 ggctgcacgg cgtagcgggt cacggcatcg agccggtcgc cgtcgcccgc ggcggtcccg
    13561 gccagatagt gccgcagcgc cggggccgga tcgaattcct cggtgcgtga gtcgatatag
    13621 ccgggtttca cggcgcgacc gcctgccggg cggcggcccg gaatccggcg gccacctccg
    13681 cgaacgcgtc gttggtcgcc ggactgccga tcgtcacgcg caccccgcgc tcggcccact
    13741 cgcgcacccg caggccgtag gcggcgcagt gcctggtgaa ttcgcccgcg tcgggagtgg
    13801 gcacccacag aaagttggcc tggctcaccg gaacctgcca gccctgctcg atcagcaggt
    13861 cccgcaggcg ggttcgctcc gcgccgacct gcgcgcaccg ctgccgcatc tccgcgaccc
    13921 cggccagggc ggccaccgcg gcggcctgcg ccggagcgct gggcgcgaag aacatgcgca
    13981 ggacggccag gcgcgcggtc agcgcgggct gggcgacgag gtagccgatc cgcagcccgg
    14041 ccagccggta ggacttcgaa aacgtgcgca gcacacacac tctcggatcc tcgcggacca
    14101 ggtcgagcgc gtcgcggtag ccggggtcga gcacgaaatc ccggtacgcc tcgtcgatca
    14161 gcaccgtgac gtggtcgggc agccggtcca ggaaccgccg cagccgctgc tgatccagca
    14221 gcgcgccggt gggattgttc ggattgcaca gcatgaccac cgcggtccgg tcggtgaccg
    14281 ctgcggccat cgcgtccaga tcggtgtcca ccccgtccag ggcgaccggc accgcgtcgg
    14341 cgcgcacgtg cccgatcatc gacggatagc cctcgaacga cggccactgg tgcaccacct
    14401 gcgcgcccgg ctcgcagcag accagcagca gaagctggca cagcgcggcc gatcccggcc
    14461 cgaacaccag atgatcggcg ggcagcccga gatgctcggc cagcgcggcg gtcgcgcccg
    14521 cggccgtcat gtccggatag tcgttggcga tggccgccgc ctccgccgcc ctcgccacca
    14581 gctgccgatc cgggcgaaat gccacggtgt tcatggacaa gtcggggtcg tcgacccatt
    14641 ctccggaatt caccatcacc ggaccctccg ctatcaaccg ccggtttcgc cgtgacgcca
    14701 ccggaaaaac tcaccaattc atgatcgaca gaattgccgg accgtccgac ctccaccccg
    14761 taccgaatgt atgccgggat catcccacgg aaaaccgatc acgggcaata tgaccggttt
    14821 cgatgttatc cagaaattat tgtccggaag cattgtttat cctaaattta tccgctcgtt
    14881 gggctgcgcg attcggatcc gcgacatacc atggcagccg tcggcttccc gttgcggcca
    14941 ggaggggtca tcgatgcctg cgaccattac cgttcagccg atttccggcg ctctcggcgc
    15001 cgagctgcga ggtatcgatc tcgcgacgct gaccgacacc gaattcgaga cggtgcacga
    15061 gctgctgctc gaatatcagg tgctgttctt cccggatcag ggcgacctgc cgccggccgc
    15121 gcatatcgcg ttcggccgcc gcttcggcga ggtcgagttg catccctatc tgccgaaact
    15181 cgagggtttt cccgaaatag ttctgatcga gtcggaccgg ggcggaaagg tcgactgctg
    15241 gcacaccgac atgacctttc acgaaagccc gccgctggtg tcgatcctgc agttgacgac
    15301 ctgcccgccg cgcggcggcg acaccatgtg gaccaatcag tatctggtct acgagcggct
    15361 gtccgcgccg ctgcgggatc tggtcgacgg cctgaccgcg gtgcattcgg tgacggcggg
    15421 cgactacacg gcctcggccg aacatccgct ggtgcgggtg catccggaga ccggccgccg
    15481 ctcgctgtat gtgaaccggc tgttcacctc gcacatcccg cagctgagcc gccccgaaag
    15541 cgacgcgctg ctccagcatc tcgtcgaatt ctccgagggc ccgcagttca cctgccggtt
    15601 ccgctggcag ccgggcgcgg tagccctctg ggacaaccgc gtcacccagc actacgcggt
    15661 caacgactac gacgagcccc gccgcggccg ccgcgtcaca gtcctgggcg accaccccga
    15721 gggcaaccca ccccgctggc cgaactacac ccccgccgac ggcgagcggt actggcccat
    15781 gcgcgtcaac gccaagtccg gctactgaaa cagcttaggc cgcaccgtca ttccggcatg
    15841 ctaccgcccg tcactccggc aagcgtccac tcgccattcc ggcaggctgc cacccgtcac
    15901 tccggcaggc tgccacccgt cactccggca agcgtccact cgtcattccg gcaggctgcc
    15961 acccgtcact ccggcaagcg gccacccgtc agtccggcgt gctgccactc atgattccgg
    16021 catgcttttg gccggaatcc atgtgccgca ctcgacctac gcggcgcgat gacgactggc
    16081 cggacgtcga tgccggaacc gcaggatcga atcctcgtgc gccacatcga tatccggcac
    16141 ctcgtccgcg aaacgctcac gcccggtatc cattcggtct ccgataggcc gatcatcgtc
    16201 gcggtgtcgg cggtacacca gatacagcag cgccaccccg agcagcaccg gaacatgcga
    16261 aatcagccgg gccgcagtca catccccgcg cgtgatgtcg agcagcgaga ccccggtcag
    16321 cacgccgacg aacacgctca gcatgggcag ctgcccggcc gcggtgcggg tgcgcagcgc
    16381 cgcccacacc agcccgatgc cgatcgccag gttccaggcc gcgctctcgt ggctcatgtg
    16441 gcccatcatg aacgcgccgt gcgccgcatg ccccatgccg gtgtcggcgc cgaacagctg
    16501 ggccagcgcc aggctggtct gcgcgacggc gacgacggcc agcgcggccc gcagcccgac
    16561 gggctcgcgg gtctgttcgg gcacggccgc catgatccgc gcggtcaggt ccggcaccgc
    16621 gggcgcagga tgcagaatcg tcgcccggcg cagctcttcg gcgcggcggt accagtcccg
    16681 gcagcccgcg cagcccacca catgccgatc gaccaccgcg gcccggatcg gttccggctc
    16741 gccgtcgata cgcgcggaca acgcttcgcg gaccgtttcg cacctcatgt ccctatggtc
    16801 gcgcagaccc gccgaagagt tcccgccacg gtatgcaagc ttccacgaca gcatgtagta
    16861 gcctgacgaa ccgtgcccgg tgacaaagac gacgagctga ccgcgcttgc cctggccgcg
    16921 ggtcgcggcg atcggcgggc attcgaacaa tgggtgcgcg ccatgcaggc cgatgtctgg
    16981 cggttccacg cctatcgcgc gggccccggc gcggccgacg acctcaccca ggagacgttc
    17041 gtccgcgcct acggcagcct gccccgattc gcgggccgcg cctcggcccg cgcctggctg
    17101 ctgtcgatcg cgcgccgcgt ggtggtcgac tccatccgct ccgcggtcgc ccgcccccgc
    17161 ctgcacgaca ccgacgactg ggagtccgcc gccgaacagc gcgccgccgt gcagcgcacc
    17221 ggccgcacct tcgaggacct cgtcgagatc cgcatgctgc tcgacggcct ggaccccgaa
    17281 cgccgcgagg ccctgatcct cacccaggtc ctgggcctgt cctaccagga ggccgccgag
    17341 gtctgcggct gccccgtggg caccgtccgc tctcgcatcg cccgcgcccg cgaagacctc
    17401 ctggccgcca cccgcgaacg cgacggcggc gtgggctgac ggccctatat gccttgacgg
    17461 gaatataacc aaagaggcac actggcggtt gtgacagtag cgttcgacgt tctcgtcgag
    17521 ccgaatcgcc gccgcattct ggatttgctg ctgcagcggc cgcagtcggt gggcgagttg
    17581 gccactcggc tcgggttgtc ccagccgggt acctcgaaac atctgcgcgt gttgcgggag
    17641 gccggtttcg tccgggtccg ggtcgacgcg cagcgccgct ggtacgagct ggatccggcg
    17701 ccgctggccg agctcgatgc ctggctggcg ccctatcgcc ggttgtgggc cgacagtctc
    17761 gacaccctcg aacgccatct cgacgccccg ccggagcccg cgaatcccga acgaggagaa
    17821 acgtcatgag ccgcaccgga accctgcgcc gcgacggcga ccgctgggag ctgcgcttcg
    17881 aacgcgaact ggcccacccg gtggagaccg tgtggcgggc cgtcttcgac tccgaccggc
    17941 tggcgcactg gtatccggcg gccgaaaggg agctggagcc ggtcgtcggc ggcaaggtgc
    18001 gcgaggtcta cggcgcgggc gagcaggcgg tgaccatcca cggcgtcgtg accgccctgg
    18061 agccgccgca cgtcctggag taccgcatgg actcctccgc ggtcgggttg gccggattcg
    18121 acgaaatccg cactctccgt ttcgaattgc acccgctccc gaccggctgc cgcctcgtct
    18181 tcctgcacac cttcggcgac cgccccggcg cggcgagctt cgccaccggc tggcaccgct
    18241 gcctggacgc actcgccgat tcccgcaccg acgcccccac ctccgccgac cccgatttct
    18301 cctggcccca gcagcacgag cggtacgtcc ggcagttcgg cctggacgag ggcacggccg
    18361 aacagaccga caccgccaca atcatccgct tcgaacgcca gctgatgatg caccccgtcg
    18421 acgaggtctg gcaggccctg accgccgggc acacccccac cgcaggcgcc gaacccccgg
    18481 cgcccttcgc cccggccggt ctccccaccg gcccggctcg caccgtcgat cccccatcac
    18541 tcctcgaatt ccataccgcc acaacgaatc cccacaccat ccgctggcaa ctccgccccg
    18601 gccccggcgg tgcgcgcatc accctcaccg acaccgcacc gcagctgacc cccgaggaga
    18661 ccgccgaagc tctggctaca tggcacgatc acatcgaaca gatcgtcgcc gacctcggcc
    18721 gacaggactg accgatcccc ttgcaccgca aggcaatacg ggcgttctac ggcagcacca
    18781 ggcaggcggg ccccaggttg atcccggtac ccacgttcac ctcggaggta acgatcgccg
    18841 cccccggcgt cggatactca cccgcccaaa tcgtgtgcac gcccgcccga tcgggcgtcc
    18901 acacggtctg agccttcccg gtatcgccgg tcggcgcccc cggcggccgc aacgtctcct
    18961 gcgtacgaac cccaccgacc tcatcgatga acaacaccga ggtccccggc ttcgcggtcg
    19021 cggtaatcgt gtacgaacac ccggtcccat acacccccga actcccgaaa ctcatccccg
    19081 gcgcaacctc gaccgcagtc acatccgcca cagcatcggg tgcagcacaa gcgaccccga
    19141 ccaccacacc gaacgccgca acccccgcgc ccaccctgga catcatccgc attcgagccc
    19201 cctcagacga agaatttccc cccggaaggg gctccaccga gaatcgcaca ccacgggtca
    19261 ccgggcaacg tggtggataa cgaagaatat ggtgtgcgat cccggccaaa agcacgccgg
    19321 gaccaacagg cccagcacac caagaccaac aggcccagca caccaggacc gacaggtccg
    19381 gcacgccggg atcagcgggt ccggcgcgcc gggatcgaca aagccccgag cgcgctcagt
    19441 gaaccgatgc gttcaccgag aagtgttggg gcgggggtgt gcccggctgc caggcgggcg
    19501 gcagtgacac caggtcgagg cgggtgttgc cgggggcgga tgcggtgaat gtccacaccg
    19561 acgttcccgg ggagccgggc atgatgttgg tcgggcgaaa ttgggggtcg ccctcctggt
    19621 gcatgacgcc ctggtcgaaa tcggccagct gccagcggta tccggtggag gggttgtcgg
    19681 ggagggcgat ggccagctcc tggccgacgg tcagcgtcac cgtctgtccg tccgcgtcgg
    19741 tacccacgat catcggttcc gagatcggcg tcgcgacggc gggtccggcc gccggatcgg
    19801 cccacgccac cgcattcgtg ccaccggcgg cgagcgccac gccgaacgcg accatcagca
    19861 aaggtgtacg caccacagtc cttccgtatc cctggatcac cacggccgac ggccgggcgc
    19921 tcacaccata ccgacgcccg cgcccatgcg cgcaccctgg ctcgcgaata cgttggtaca
    19981 caacgccact cagtacttac gcgccacccc gccgtacgcc cccgacatct ccgggcactc
    20041 ccccacatcc gccggatcgt ccggccgcca cagcggcagc ggcaccagcc ccggcgcgag
    20101 cagcgtccaa tcggcgaagt aggcgccgat ctgttcccgc gaccgcagga cgatctcggt
    20161 cgaggtgcgt ccggacagct tctgcgccgc cagcacctcg gcgggctgcc cgtcggcggt
    20221 cgcgtgggtg atggccagat agctgccggg cgccaccgcc tcccgcagcc gcgccacgct
    20281 cgccgccggg tcggccccct ccggcacgaa atgcagcaca cccagcagca gcaccgccat
    20341 cggccgccgg aaatccagca gccccgtcgc cgccgcctcg gccagaatcg cctcgggctc
    20401 ggccacatcc gcctgaatca ccgtcgcgcc cggattgtcc gcgaggatgg cgcggctgtg
    20461 cgccacggcg accggatcga tgtcgacata caccacgctc gcccccggat tgcgggcctg
    20521 cgccacctcg tgcacgttgc cgaccgtcgg aatccccgac cccagatcga ggaactgatc
    20581 gatcccggcg tccaccagca gccgcacaca ccgccgcagc agatcccgat tggcgcgcat
    20641 ggtttcggcg acattcggtg tgaacgcctc gatctggcgc gccagcgccc ggtcgatctc
    20701 gaaattgtgc atcccgccga cgaagtagtc gtacacccgg gaggcactgg gccggtccag
    20761 gtcgatgccc tccggcgccc aatcaggtct ggtcattccc gctctctccg ctaccgcgcc
    20821 ccgccggaag gccaggcacc gcaatcgtat tcgagcatct gcgaaatggt tgcggttcac
    20881 atgttgccgc cgacccggct acgatcgatc ttcatggcgt gggatgggtc cgatctcgac
    20941 ggcccgcacg cggaactggc cgagcggtgg gcggccgcgc tcggcggcgg cgctcgcgat
    21001 cacgtcgtgc cgttgagcgc gagcgagaca cgggagttgc tgacccgtct cgccgccgac
    21061 ctcgtcaccg ccacccacac cggcgacccc gcccgcgccg ccgaactcgg cgccgaactg
    21121 gcccgcgcgc acttcgtcgg cgacgaggtc ctcggccgca gcatcgccgt cctggagcgc
    21181 tatttcgccg acaccggcgc gccctgcccc gccgccgtgc tcggcgcgtt cgcctccggc
    21241 tacgtgcgcg ccttccgcgc ctggctgctc gccgaacagg agagcgtgcg cgccgccgac
    21301 atcgccgccc gccgcgtggt cgagcagcag ctgcgcggca gcgaggcccg gttgcgagcg
    21361 gtgttctccc aggccggaat cggcaccggc ctgtcggata tgagcggccg gatcatcgag
    21421 gtcaacaccg cgttcgcgac catgctcggc taccgccccg aggagatgac ccggttcacc
    21481 gtcaccgacc tggcccaccc cgacgacccg cccggcatgt gggagctcta cgcgggcgtg
    21541 ctgcgcggcg agcacgacag cgtgcagttg gagaaggcgt accgccaccg cgacggccac
    21601 accgtgtgga ccaatatcaa cgtctcgctg atccgcgacg aacagggcct gccgcagtac
    21661 acgctggtcc tggtggagga catctccgag cgccgcgccc tgcgcgagcg gctgacctac
    21721 cgcgccctcc acgacccgct caccggcctg gccaaccgat cccgcttctt cgacgccctc
    21781 accaccgcct tcgccgatcc gaccgcccgg gtcggcctgt gctacgtgga tctggaccat
    21841 ttcaagaccg tcaacgacac cctcggtcac gccgtcggcg acgtgctgct cacccaggcc
    21901 gccgcgcgcc tgaccgcctg cgcgtgcggc cccgatcagc tggtggcgcg gatgggcggc
    21961 gacgaattca tcatcctggt gccgcgcgcc cgcaactccg gcgaactggc cgagctggcc
    22021 cgcacggtgg tcgacgcctt cagcgtgccc ttcgacatcc tcggccaccg cctgaccgtc
    22081 accgccagcg tcggcgtgat gatcgaacgc accgcccaca ccaccaccga cgagctgctg
    22141 caggccgccg acaccaccat gtactgggcg aaaaccgatg ggcgcgcccg ctattcgatc
    22201 ttcgacccgg atcgccgccg ccgcgagcac acccgcgccg agctgaccgc ggccatgccg
    22261 gcggcgctcg cacgcggcga gttctacctc gactaccagc ccatcgtcgc gctcgccgac
    22321 cagcgcccgc tggccgtgga ggcgctggtg cgctggcggc atccggcgct cggcgtgctc
    22381 agcccggcac gattcgtcga cctcgccgag gacagcgggc acatcgccgc gctcggcacg
    22441 gtggtgctcg agcaggcgtg ccgcgacggc cgccgctggc acgacgagtt cggcgcgcac
    22501 accccggtgg tcagcgtgaa cgtctccgcc gccgaggtcg ccgacccggc ctggctgcac
    22561 cgggtgcagc ggatcatcac cgacaccgga ttcgaccctg ccagactgca attggagctg
    22621 accgagcgca ccttcatgca cgccaccggg cggccgctgc aggcgctgcg caccctcgcc
    22681 gaggccggag tccgcatcgc catcgacgat ttcggcaccg gctactccaa cctcgcctat
    22741 ctgggccgac ttccgttgca cgtggtcaag ctggccgggc cgttcatcca ccgcatccgc
    22801 agcgcgggca ccgccgaccg cagcgatctg ctcatcctgg aaaccatcat cggcctcacc
    22861 cacggcctgg ggcttaccgt caccgccgag tgcgtggaga ccggccatca ggccgaccgg
    22921 ctgctcgacc tcggctgcga caccgcgcaa ggctggctgt tccaccgtcc gatgcccgcc
    22981 gaccggatca cggcgctgct caccgcggcc tgcgtgcatc ccgccgaata gaaccgtccg
    23041 gtcgcacatc gttaccatcc gggagagaat gcagcgatga tgcagattta ctacgggtgg
    23101 tttctcctgc tgtacggcgg ggaaaggttg ctggagcagt tcttccgatc gtgagtagtc
    23161 gcgatcggag tcttgccgcc acccgaaggg agcacgacca tgtccacgat cctgtacgcc
    23221 ctgctacagc cgctactcgg taacgacacg gccggttact ggtcctcgat cttcgtcatc
    23281 ggccccaccg actgatcagc ccgccggacc ggtggatccc gggccggggg cgcgcgacgt
    23341 ggcacactgc cctacgcccc cgaccgaaag gccgacgacc gatgcagagc acccgaatcg
    23401 tgctggcttc ccgcccgacc ggcatgccga cggcggagaa cttccggacc gagaccgtcg
    23461 agctgcccgc cctcgcaccc ggcgaggccc tgctccagac gctgtacctg tcgctggacc
    23521 cgtacatgcg cgggcggatg agcgacgccc cgtcctacgc cccgccggtg cggattgggc
    23581 agcccatggt cggcgccacc gtctcccggg tcctcgaaac caccgacgac a
//
