LOCUS       NZ_KV411304            21086 bp    DNA     linear   CON 12-FEB-2024
DEFINITION  Nocardia terpenica strain IFM 0406 scaffold2, whole genome shotgun
            sequence.
ACCESSION   NZ_KV411304
VERSION     NZ_KV411304.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardia terpenica
  ORGANISM  Nocardia terpenica
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 4638951)
  AUTHORS   Buchmann,A., Eitel,M., Koch,P., Schwarz,P.N., Stegmann,E.,
            Wohlleben,W., Wolanski,M., Krawiec,M., Zakrzewska-Czerwinska,J.,
            Mendez,C., Botas,A., Moris,F., Cortes,J. and Gross,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-APR-2016) Pharmaceutical Biology, University of
            Tuebingen, Auf der Morgenstelle 8, Tuebingen 72076, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 30-JUL-2014
            Assembly Method                   :: CLC NGS Cell v. 7.0.4
            Genome Coverage                   :: 118.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/12/2024 01:56:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,832
            CDSs (total)                      :: 8,760
            Genes (coding)                    :: 8,562
            CDSs (with protein)               :: 8,562
            Genes (RNA)                       :: 72
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 40 of 198
            Pseudo Genes (incomplete)         :: 174 of 198
            Pseudo Genes (internal stop)      :: 9 of 198
            Pseudo Genes (multiple problems)  :: 23 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:51:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1338825
            Orig. end                         :: 1359911
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KV411304.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="8"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11086](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11086)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(371..386)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.98"
                     /tool="antismash"
     gene            955..1782
                     /locus_tag="AWN90_RS27005"
                     /old_locus_tag="AWN90_27030"
     CDS             955..1782
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011209393.1"
                     /locus_tag="AWN90_RS27005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27030"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_067588399.1"
                     /transl_table=11
                     /translation="MAEYRIDDLARAAGTTSRNVRAYQERGLLPAPTRRSGRALIYDDT
                     HLARLKIIDALLQRGFTTAHIADFITSWETGKDLTEILGLQQAVTATWGTPEEPLEVPR
                     ELVDTVLSDGDGEPVDDTQLSRLAELDVVRMHGDTIEFVRPELLETFAQLNNYGFGLSG
                     LIDLYTAVVSRLDDIARLMVLAAKDHIVAEHGPGWLPDSDAEIAETTAMLNRLRDLGAR
                     SARDGLDQALDRVLRSELSGYLETAAEKRFGVGTKDRHNVVGAAKKGADGKQH"
     gene            1823..2158
                     /locus_tag="AWN90_RS27010"
                     /old_locus_tag="AWN90_27035"
     CDS             1823..2158
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019927967.1"
                     /locus_tag="AWN90_RS27010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27035"
                     /product="Lsr2 family protein"
                     /protein_id="WP_067588403.1"
                     /transl_table=11
                     /translation="MAKQVTVTLVDDFDGKSKADETVYFSIDGRDYEIDLSMKNAGKLR
                     EILEPWTANARKLGRVGRRGGGRARAAGNAEQTAAIRKWAQQHGHEISSRGRIPAKIID
                     AYHKAKK"
     misc_feature    2171..2186
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.78"
                     /tool="antismash"
     misc_feature    2306..2324
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.0"
                     /tool="antismash"
     gene            2324..3745
                     /locus_tag="AWN90_RS27015"
                     /old_locus_tag="AWN90_27040"
     CDS             2324..3745
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020730752.1"
                     /locus_tag="AWN90_RS27015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27040"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_067588404.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.5e-41, bitscore:
                     140.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYDVVVFGAGPVGENVADRAHAAGLSVAVVERELAGGECSYWGC
                     IPSKALLRPVLAVADARAVDGARQAVTGRLDTPAVFARRDGFVSNWDDAGQVDWIEKHG
                     LDFVRGHARLDGPRRVVVEAADGGTTVLLARHAVAICTGSRAAVPALPGIEEARPWTNR
                     RATDSSAVPGRLAVVGAGPVGVEMATAWQGLGAAVTLLVRGKGLLPRMEPFAGELVADR
                     LGAAGMDVRLGVSVRALRRPDPAGPVTLSLSDGRELEVDEVLFATGRVPNTDDIGLDTI
                     GLTPGDWLEVTDSCQVRGPHEDWLFALGDANHRALLTHQGKYQARIVGNVLAARAAGQP
                     VRSDPWSPHTATADTRAVPQVVFTDPEAAGVGLTAEQAERAGHRTRVVDIDLGAVAGAA
                     LYADGYRGQARMVVDQDENRLLGVTFVGPGVAELITSATIAVAAEVPLDRLWHAVPCFP
                     TISEVWLRLLEAYRG"
     misc_feature    complement(4027..4045)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.2"
                     /tool="antismash"
     misc_feature    4030..4048
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.2"
                     /tool="antismash"
     gene            4069..4518
                     /locus_tag="AWN90_RS27020"
                     /old_locus_tag="AWN90_27045"
     CDS             4069..4518
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003940568.1"
                     /locus_tag="AWN90_RS27020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27045"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_067588406.1"
                     /transl_table=11
                     /translation="MTDPLALEQQVCFPLYAVSRAMTSVYRPKLEALGLTYPQYLVMLV
                     LWEHDDRSVGELCSALALDSGTLSPLLKRLEGAGYVERARAVDDERRVDVRLTERGREL
                     RERACVIPAEMAEATGLSLEELGALRETLLRMNRALVAHTRSKEK"
     gene            4520..4942
                     /locus_tag="AWN90_RS27025"
                     /old_locus_tag="AWN90_27050"
     CDS             4520..4942
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011597188.1"
                     /locus_tag="AWN90_RS27025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27050"
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="WP_067588408.1"
                     /transl_table=11
                     /translation="MTVLYTAEALATGDGRNGHARTTDGKVDVALSIPKEMGGTGEGTN
                     PEQLFAAGYAACFHSALRLVARQAGANVDDSAVGAKVGIGPDETGGFRLEVTLEVSLPH
                     LAHEQAQDLADRAHQVCPYSNATRGNIDVHVVVAED"
     gene            4955..5935
                     /locus_tag="AWN90_RS27030"
                     /old_locus_tag="AWN90_27055"
     CDS             4955..5935
                     /NRPS_PKS="Domain: PKS_ER (18-308). E-value: 7.8e-30.
                     Score: 96.0. Matches aSDomain:
                     nrpspksdomains_AWN90_RS27030_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008376832.1"
                     /locus_tag="AWN90_RS27030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27055"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_067588410.1"
                     /sec_met_domain="ADH_N (E-value: 1.6e-10, bitscore: 38.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.2e-15, bitscore:
                     55.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVVVENFGEPKDVLTPAERPTPEPGPGQVRIAMTLSPIHNHDL
                     AIVRGVYGYKPPLPTVPGTEAVGRVDAVGPDVTGVSAGQRVVVRGAQGAWAEYFLAEAA
                     QLIPVPDTIPDETAAQLLSMPLSALILLDDLRVRAGDWIAVNAANGAVGRLLNALAAER
                     GVRVLNLVRSEAAVTALRASGAEAVVSTEAADWRDAVTAATGGAPIVRVIDQVGGPAGG
                     ELLTLLAPGGELISFGAMSGERLVLNTGALIFKQAVVKGFWAARRMEEIGREATVRLIG
                     ELVAAAERGVLRLDIEAAYPLADAAEAAAASERPGRNAKIALRPA"
     aSDomain        5009..5878
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AWN90_RS27030_PKS_ER.1"
                     /evalue="7.80E-30"
                     /label="AWN90_RS27030_PKS_ER.1"
                     /locus_tag="AWN90_RS27030"
                     /protein_end="308"
                     /protein_start="18"
                     /score="96.0"
                     /tool="antismash"
                     /translation="AERPTPEPGPGQVRIAMTLSPIHNHDLAIVRGVYGYKPPLPTVPG
                     TEAVGRVDAVGPDVTGVSAGQRVVVRGAQGAWAEYFLAEAAQLIPVPDTIPDETAAQLL
                     SMPLSALILLDDLRVRAGDWIAVNAANGAVGRLLNALAAERGVRVLNLVRSEAAVTALR
                     ASGAEAVVSTEAADWRDAVTAATGGAPIVRVIDQVGGPAGGELLTLLAPGGELISFGAM
                     SGERLVLNTGALIFKQAVVKGFWAARRMEEIGREATVRLIGELVAAAERGVLRLDIEAA
                     YPLADAAEA"
     gene            complement(5943..7106)
                     /locus_tag="AWN90_RS27035"
                     /old_locus_tag="AWN90_27060"
     CDS             complement(5943..7106)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020100045.1"
                     /locus_tag="AWN90_RS27035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27060"
                     /product="damage-control phosphatase ARMT1 family protein"
                     /protein_id="WP_067588412.1"
                     /transl_table=11
                     /translation="MTDVPPILAGVPGTFPHSVFHERHPRLIEQVIGAHPYGPAARAGL
                     RELLAESTSGTVRPPEPGGERVAPWLEWGREMWSRPWGEVPFLWAESYFYRRLLDAVGY
                     FGEGPWRRIDPFGPTKAAELYGRAVDDELAALDTLVDRLIDSIRDALLRSALWGNQADL
                     GFRLTAESGTVDTRLLVDDSAALWAALERTPGATVALIADNAGRELLPDLVLADHLLTE
                     NLAGRVVVHVKPHPYYVSDATMTDLLAALRRLRDADTPQAQRVGQRLWQAMADDRLVVR
                     AHEFFCAPLHFHDMPTDLTDELTGAAMTILKGDLNYRRLVGDRYWPPTTPFAELVRYFP
                     TPVTALRTLKSDVVVGLSAEQVRTLDAAGENWRSSGKHALIQSNAAA"
     misc_feature    complement(7108..7123)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.94"
                     /tool="antismash"
     misc_feature    complement(7202..7217)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.98"
                     /tool="antismash"
     misc_feature    7544..7559
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     misc_feature    complement(7689..7704)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     misc_feature    8018..8033
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.98"
                     /tool="antismash"
     misc_feature    complement(8112..8127)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.94"
                     /tool="antismash"
     gene            complement(8197..8442)
                     /locus_tag="AWN90_RS46090"
                     /old_locus_tag="AWN90_27065"
     CDS             complement(8197..8442)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS46090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AWN90_27065"
                     /product="hypothetical protein"
                     /protein_id="WP_067588414.1"
                     /transl_table=11
                     /translation="MTDVPPILAGVPGTFPHSVFHERHPRLIEQVIGAHPYGPAARADS
                     LAQLEPSADAVAAAVRAARAAGPYGCAPITCSISLG"
     misc_feature    complement(8444..8459)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.94"
                     /tool="antismash"
     gene            8581..9321
                     /locus_tag="AWN90_RS27045"
                     /old_locus_tag="AWN90_27070"
     CDS             8581..9321
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019926918.1"
                     /locus_tag="AWN90_RS27045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27070"
                     /product="serine/threonine protein phosphatase"
                     /protein_id="WP_231951648.1"
                     /transl_table=11
                     /translation="MQNAVTTAITRRELVRLIGITGESVSRRGLRSINADAVATATDPV
                     AGRTAFVVADGVGDHLLAARAARTAAATAARVGAHDGALAGIVAAQAQLLREFPEPSAD
                     AVAVVAVLPTPERPDAPTEIAWVGDCRAYRWNGRVLHQITVDHTVAEYFRARGRIAAPR
                     MSHLVTTSVRTVRPGGIGFASTGSSRGRLLLSTDGVHKRVGMATLKELLGGGAAPGATA
                     DALVDLALRTGGSDNATALVVDHQ"
     misc_feature    9268..9270
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            9350..9556
                     /locus_tag="AWN90_RS27050"
                     /old_locus_tag="AWN90_27075"
     CDS             9350..9556
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019932923.1"
                     /locus_tag="AWN90_RS27050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27075"
                     /product="DUF5808 domain-containing protein"
                     /protein_id="WP_067595842.1"
                     /transl_table=11
                     /translation="MPSTNDDDRVPEPEGKALGLPYDWRRPTAQRTRSRIWNPDDPRLF
                     TPKSFGWGYGLNLYRLFHWRRRG"
     gene            complement(9758..9934)
                     /locus_tag="AWN90_RS46095"
     CDS             complement(9758..9934)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS46095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_156674473.1"
                     /transl_table=11
                     /translation="MHGDTPCGGPAQGTEFAATSPPIMASGLFPISGCASTVRASSLPV
                     TNQPSVPDDVVNR"
     misc_feature    complement(9806..9808)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..11086)
                     /locus_tag="AWN90_RS48415"
                     /old_locus_tag="AWN90_27080"
     CDS             complement(10001..11086)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011210023.1"
                     /locus_tag="AWN90_RS48415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27080"
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_067588415.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 4.1e-42, bitscore:
                     142.7, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTDLLVCGLGPAGRALTHRALAHGYSVTAVDPHPDRRWVATYGA
                     WADELPGWVAPVGTTAGRLAAWGSRRFEIERAYVVFEGGALQDSLTVAGARVVRDHVID
                     IDRTAESPASVRLSTGTTLTARRVIDARGVARSPARAEQTAYGVVVPRRSWGETLFMDW
                     RPDNGAGPDDPRSFLYAVPLRADAMLLEETCLAGRPALDGAVLRDRLLTRLRCRGIELD
                     GSEPVERVRFPVTGGRPGRARFGAAGGLLHPATGYSVATSLSLSDAVVAGESIWPVSAH
                     AVHLLRAAGLRALLALPPQDLPLFFDAFFDLPIELQRAYLSGHSDFRGTAAAMNRIFRA
                     LPWRLRRTLATAVAPIPLLTK"
     misc_feature    complement(10013..10015)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(10064..10066)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(10214..10216)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11212..12537
                     /locus_tag="AWN90_RS48420"
     CDS             11212..12537
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS48420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_156674474.1"
                     /transl_table=11
                     /translation="MSYPPGSGPYGQQPQDAPGRGQHPGGQPQPGWNAQQSDWEQPQSA
                     WNQQQAASQPQATQQQAAWGGQQVVDQQQSAWGEQQAAGLPQATQQQRQAVWGQPQVAQ
                     QQVVWGDQQAVGQQQSVSGEQQVAGQQRPGWGEQQAVGQQQPAWGDQQAAGQQQSAWGE
                     QQLAGQQEPGWGQQHAVGQQQPAWGQQQAVWDQQQPSAWGQQPPQAWGQPGYPGGYSPQ
                     PPKKNTGLIVGIVLGVVAVLVIGVGIVVLATRHKSDNAASAAAATPSLVPATTSSTATG
                     RPTTTPSSSASSRFSYQEQAKDWNFKLGDVSLHADWVAGVDHPTCADIEKNGKLTSLGC
                     QYAAEMVYRAEDGGLMLTQFVMGMADADKASAASGQYSDSDLNLRPGSYIDHFAVGKWR
                     DGSQGQYLVLTMVTATDAVDEDTAKKYLRYLHADMLGALTFR"
     gene            complement(12549..13313)
                     /locus_tag="AWN90_RS27070"
                     /old_locus_tag="AWN90_27095"
     CDS             complement(12549..13313)
                     /NRPS_PKS="Domain: PKS_KR (10-176). E-value: 1.7e-07.
                     Score: 23.2. Matches aSDomain:
                     nrpspksdomains_AWN90_RS27070_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019047732.1"
                     /locus_tag="AWN90_RS27070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27095"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_067588421.1"
                     /sec_met_domain="adh_short (E-value: 1.6e-30, bitscore:
                     104.5, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 7e-36, bitscore:
                     122.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSADLKGKGALVTGASRGIGKAVAAELLASGAQVLITARKPEPLE
                     QTAAELRALGHPGKVVAVAGNSGDADARAEAVATAVAELGSLDILINNTGINPVYGPLM
                     DADLDAVRKIFDVNVVAALGYTQEAYKGWMREHGGAVVNVASVAGLRSTGVIAAYGASK
                     AALIRLTEELAWQLGPTIRVNAVAPGVVKTKFADALYSADEDAAAAAYPLKRLGNPEDV
                     AALIAFLVSDQASWITGEVVRVDGGLLATGGI"
     aSDomain        complement(12786..13283)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AWN90_RS27070_PKS_KR.1"
                     /evalue="1.70E-07"
                     /label="AWN90_RS27070_PKS_KR.1"
                     /locus_tag="AWN90_RS27070"
                     /protein_end="176"
                     /protein_start="10"
                     /score="23.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LVTGASRGIGKAVAAELLASGAQVLITARKPEPLEQTAAELRALG
                     HPGKVVAVAGNSGDADARAEAVATAVAELGSLDILINNTGINPVYGPLMDADLDAVRKI
                     FDVNVVAALGYTQEAYKGWMREHGGAVVNVASVAGLRSTGVIAAYGASKAALIRLTEEL
                     AWQ"
     CDS_motif       complement(13206..13283)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AWN90_RS27070_0001"
                     /evalue="8.00E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="AWN90_RS27070"
                     /protein_end="36"
                     /protein_start="10"
                     /score="15.3"
                     /tool="antismash"
                     /translation="LVTGASRGIGKAVAAELLASGAQVLI"
     gene            13481..15112
                     /locus_tag="AWN90_RS27075"
                     /old_locus_tag="AWN90_27100"
     CDS             13481..15112
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011559842.1"
                     /locus_tag="AWN90_RS27075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27100"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_067588423.1"
                     /transl_table=11
                     /translation="MITATDLEVRAGIRTLLTAPGPALRVQAGDRIGLVGRNGAGKTTT
                     LRILAGEGEPYAGKVIRSGETGYLPQDPREGNLDVLARDRVLSARGLDTLIRDMEKQQA
                     LMAEVADEAEREKAVRKYGRLEDRFSALGGYVAESEAARICHSLGLPDRVLGQALRTLS
                     GGQRRRIELARILFAASDGSGGKSDTTLLLDEPTNHLDADSITWLRGFLQSHDGGLIVI
                     SHDVELLEAVVNRVWFLDAVRGEADVYNMGWKKYLDARATDEQRRRRERANAEKKASAL
                     KAQAAKMGAKATKAVAAQNMVKRAERLLAEADEVRVSDKVARIKFPQPAACGKTPLMAE
                     NLTKVYGSLEIFTGVDLAIDRGSRVVVLGLNGAGKTTLLRMLAGVEQPTAGGLVPGHGL
                     KIGYFAQEHDTLDDTATVWENIRHAAPDAGEQDLRGLLGAFMFSGPQLEQPAGTLSGGE
                     KTRLALAGLVSSAANVLLLDEPTNNLDPISREQVLDALRSYAGAVVLVTHDPGAAEALN
                     PERVIMLPDGTEDHWSQDYLELIQLA"
     misc_feature    15176..15191
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            15261..15500
                     /locus_tag="AWN90_RS27080"
                     /old_locus_tag="AWN90_27105"
     CDS             15261..15500
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011210020.1"
                     /locus_tag="AWN90_RS27080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27105"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_067588425.1"
                     /transl_table=11
                     /translation="MSDRPAQGKSTLGKGTRVTGKSRDRLQTQLKKQYEAGASIRSLAR
                     ETGRSYGFIHNVLVESHVQLRSRGGANRRKSAAK"
     gene            complement(15690..16190)
                     /locus_tag="AWN90_RS27085"
                     /old_locus_tag="AWN90_27110"
     CDS             complement(15690..16190)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019925655.1"
                     /locus_tag="AWN90_RS27085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27110"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_067588427.1"
                     /transl_table=11
                     /translation="MTTLPRKPVAVRRAQDAETLRTEAVTVRLLIDSEEAGHGVSTVEV
                     SMARGADGAAPHYHTRSDELFYVVEGELQVLADDEIVTVGAGGALVVPKFMPHAFGAAP
                     DSAARILIALMPGVQRFGYFRLLERVARGEATLADLGASQEEYDNHFVDAPRWWAERTA
                     NRR"
     misc_feature    complement(16206..16220)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.52"
                     /tool="antismash"
     gene            16261..16773
                     /locus_tag="AWN90_RS27090"
                     /old_locus_tag="AWN90_27115"
     CDS             16261..16773
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019925654.1"
                     /locus_tag="AWN90_RS27090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27115"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_171983254.1"
                     /transl_table=11
                     /translation="MPDQQPDAIDAIVTQWRRERPDLDLEAMAIVGRLGRLHLVAERAV
                     ERVFADHGLQRGEFDVLAALRRSGEPFELNPSVLADTLMLSRAGMTGRLDRLESAGLVR
                     RIADAGDRRAVRVALTESGRALVDRVVAAHTANETRLLSVLSAQDRDHLNRIARTLLAA
                     LESDPAR"
     gene            complement(16879..17838)
                     /locus_tag="AWN90_RS27095"
                     /old_locus_tag="AWN90_27120"
     CDS             complement(16879..17838)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011210019.1"
                     /locus_tag="AWN90_RS27095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27120"
                     /product="hypothetical protein"
                     /protein_id="WP_067588428.1"
                     /transl_table=11
                     /translation="MAVRAAGPVLIVTESEDLHADAMAATLRKQHGLTPIRLDMRDFPS
                     HSGSFRLDRAGTARALAPLAGLDDVTAVWWRRPHPCRVPGGVRRADDDYRQAECDGFLQ
                     GLLWSIPALWVNDPGADRTAGRKIVQLETARRSGFPIPETLITNDPDEARSFIESRPGA
                     VVYKRTGTGRTEFAETRLVTPADFDRLATIRSAPTTFQDYIDADCDLRVVWIDGVEWAV
                     RIDSQAGVGRVDSRLDASVAFTPERLPAAISKALTTLMGALGLTFGVLDLRVGRDGEYY
                     FLEVNPQGQFAYLEIKTGLPIFASLAKFLVHGDATVTR"
     gene            complement(17848..18303)
                     /locus_tag="AWN90_RS27100"
                     /old_locus_tag="AWN90_27125"
     CDS             complement(17848..18303)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014986325.1"
                     /locus_tag="AWN90_RS27100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27125"
                     /product="hypothetical protein"
                     /protein_id="WP_067588430.1"
                     /transl_table=11
                     /translation="MTDVLRPRSGTLEAAPALPGRLVAESDRAISVRVTEGTWTFDRAD
                     VLDIDDCATGEFDAAPDGRAVLVRIRPGATADFTQRLRIELTERPMTLPQRPSPARGDE
                     QLRTLTERWARGLRLPEVTGTGGATWTFCQTRTSGRSDDGVACDSLD"
     misc_feature    complement(18464..18479)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.49"
                     /tool="antismash"
     gene            complement(18479..18895)
                     /locus_tag="AWN90_RS27105"
                     /old_locus_tag="AWN90_27130"
     CDS             complement(18479..18895)
                     /EC_number="3.1.2.-"
                     /GO_function="GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014350849.1"
                     /locus_tag="AWN90_RS27105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27130"
                     /product="acyl-CoA thioesterase"
                     /protein_id="WP_067588432.1"
                     /sec_met_domain="4HBT_2 (E-value: 1.7e-22, bitscore: 78.2,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFSVPVTVRGYEIDVNGHLNQAVYHQYAEHARWENMRAAGLTPD
                     KLAAAGLGPVVLESTVKYLRELHIGDEVTVTSAFEWTEGKIFRMSQQIVKLDGTVSAEF
                     TVTLGLLDLSARKLVPDPIERFIELAESRELLGL"
     gene            19085..19885
                     /locus_tag="AWN90_RS27110"
                     /old_locus_tag="AWN90_27135"
     CDS             19085..19885
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014986322.1"
                     /locus_tag="AWN90_RS27110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27135"
                     /product="hypothetical protein"
                     /protein_id="WP_067588435.1"
                     /transl_table=11
                     /translation="MIDVITFRGVGEPRDADGDPAGMQQAVTDLLDPRFFHGFEPDWPA
                     SIGPDPDLWGPSLDTSVRDGIAAGVQAIQDSPNVCGLLSYSLGGLCVSGILEGMRSGEY
                     TNADGSPLQVAFAVNIANPVRAAGDSVNNLCPANTFGLHGQHGPWPASVQVREYANPGD
                     IITASPADSPLHIIDVGISPFSFVEGARFGNVTYLIFQELLRFLLLDPVANLQRYADAV
                     NGVIGYLTPWPDGQHVLYNAHPIPGTNVVWTTHAAEWINATFGH"
     gene            complement(19882..20448)
                     /locus_tag="AWN90_RS27115"
                     /old_locus_tag="AWN90_27140"
     CDS             complement(19882..20448)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003944970.1"
                     /locus_tag="AWN90_RS27115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_27140"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_067588438.1"
                     /transl_table=11
                     /translation="MPKVSDDHLAARRSQILDGARRCFAEYGYEGATVRRLEEAIGLSR
                     GAIFHHFRDKDALFLALAQEDAERMAEVAANQGIVQVMREMLANPSQYNWLGTRLEIAR
                     RLRTDPEFAAGWTQRSAELTAATLARLERRKAAGALRDDVPTDVLLGYLDLVLDGLIAR
                     IASGHANDNLEAVLDLVEASVRRKH"
     misc_feature    21047..21058
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 20.11"
                     /tool="antismash"
ORIGIN
        1 gtcaaccggc ccaccggcga tcgcacccgg caggtctacc ggcacctgcc catcacccag
       61 acgctggcgc gcgaggcgtg gttctgggga cacgagtccg tggcgctcgg cgtggtctgg
      121 aattccccgc tcacccgcct ggtggaatcg gtcgccctgc tgcacctgcg cacccaggtg
      181 cgcgacccgt ggctgcggcg gcaactgacc ccggatttcc gggccggatg taaaagactg
      241 ctgctgagca acgactacta tcccgcactg cagcaatcga attgcacact gatcacctgg
      301 ccgatcgcgc ggctgtccga acacggaatt cgcaccgccg agggtatcga acaccgcgcc
      361 gactgcatcg tgttcgccac cggattcgac gtgtccaaga ccggcacgcc gattcccgtc
      421 accggctgcg acggccgcgt gctcgccgag gaatggcggc gcggcgccta cgcgtacaag
      481 agcgtgacgg tcgccggata tccgaatctg ttcctcacct tcgggcccaa ctccggaccc
      541 ggacacaatt ccgcgctggt ctacatggag gcgcagatcg actatctcac cgacgccatc
      601 ggcgtgctgc tcgcgcgcga tctgcacagc ctcgaggtgc gccgggaccg ccaggaccgc
      661 tacaacgccc ggctgcaacg ccgcctcgcc gccaccacct ggaattcggg ctgccgcagc
      721 tggtatctca ccgaggacgg tttcaacgcc accatgtatc ccggattcgg tacccagtac
      781 acccggcaat tggcaacggt cgacctcgcc gactacgtgc tgaccccgcg cgccgccggg
      841 cacgcgccgg acgccgacgc ccgaatctcc gccgcgctga gctaatgtcg aagcaacgcg
      901 cgggtggtgc gcgccgtcgg cgagcggatc ggtgaaagga cgggcgaggc tgggatggcg
      961 gaataccgca tcgacgatct cgcccgtgcc gccggcacga ccagccgcaa tgtgcgcgcc
     1021 taccaggaac gcggcctgct gcccgcgccc acgcggcgca gcgggcgcgc gctcatctac
     1081 gacgacaccc acctggcccg gctgaagatc atcgacgcgc tgctgcagcg cggcttcacc
     1141 accgcccaca tcgccgactt catcaccagc tgggaaaccg gtaaagatct caccgagatc
     1201 ctcggcctgc agcaggccgt caccgccacc tggggcaccc ccgaggagcc gctcgaggtg
     1261 ccgcgcgaac tggtcgacac cgtcctcagc gacggcgacg gcgagccggt cgacgacacc
     1321 cagctgtccc ggctcgccga actggacgtg gtccgaatgc acggggacac catcgaattc
     1381 gtgcgaccgg aactgctgga gaccttcgcc cagctgaaca actacggctt cggcctgtcc
     1441 gggctgatcg acctgtacac cgcggtggtg agccgcctcg acgacatcgc ccggctcatg
     1501 gtgctcgcgg ccaaggacca tatcgtcgcc gagcacggcc ccggctggct ccccgactcc
     1561 gatgccgaga ttgccgagac caccgccatg ctcaaccggc tgcgcgacct cggcgcccgg
     1621 tccgcgcgcg acggcctgga ccaggccctg gaccgggtgc tccgcagcga actgagcggc
     1681 tatctggaaa ccgccgccga aaagcgattc ggggtcggta caaaagaccg acacaatgtc
     1741 gtcggcgcgg caaagaaggg tgcggacgga aaacagcatt agcattccga tagcgaatcc
     1801 gagaaaaggg aggaacctat cgatggccaa gcaggtgacc gtcacacttg tcgacgactt
     1861 cgacggcaag tccaaggcgg acgagaccgt gtatttctcg atcgacggcc gggactacga
     1921 gatcgatctg tccatgaaga acgcgggcaa gcttcgcgaa atcctggaac cgtggactgc
     1981 caacgcgcgc aagctcggcc gcgtcgggcg gcgcggcggc ggtagggcac gcgcggccgg
     2041 aaacgccgag cagaccgccg cgatccggaa atgggcgcag cagcacgggc acgaaatctc
     2101 gagccgcggc cggattccgg cgaagatcat cgacgcgtac cacaaggcga agaagtagcg
     2161 attggtccga aacgctattg cttctcctga tggcggacat cgagacgcgc ccgccgtcga
     2221 ctggcatcct ggccggggac gatcggtgcc cggaaggcgg tagcgccgaa ccggattcgg
     2281 gagaagggat gcgcgcgtgg cttcggaggc gaatggtacg gaaatgacct acgacgtggt
     2341 tgtattcggc gcgggcccgg tcggcgagaa cgtggccgac cgcgcacacg cggcgggact
     2401 gagcgtcgcg gtggtggagc gggagctggc gggcggcgaa tgctcgtact ggggctgcat
     2461 tcccagcaag gcgctgctgc ggccggtgct cgcggtcgcg gacgcgcggg cggtcgacgg
     2521 ggcgcggcag gcggtcacgg gtcggctgga cacgcccgcg gtcttcgcgc ggcgcgacgg
     2581 cttcgtgagc aactgggacg acgccgggca ggtcgactgg atcgagaagc acggcttgga
     2641 cttcgtgcgc ggccacgccc gcctggacgg accccgccgg gtcgtcgtcg aggcggccga
     2701 cggcggcacg acggtgctgc tcgcgcggca cgcggtggcg atctgcaccg gcagccgcgc
     2761 cgcggtgccc gcgctgcccg gcatcgagga ggcgcggccg tggaccaatc gccgcgccac
     2821 cgactcgagc gcggtgcccg gccggttggc ggtggtgggc gcgggaccgg tcggcgtcga
     2881 aatggccacg gcctggcagg gtttgggcgc ggcggtgacc ctgctggtgc gcgggaaggg
     2941 gttgctgccg cggatggagc cgttcgccgg ggaactggtc gcggaccggc tcggcgcggc
     3001 gggaatggat gtgcggctgg gcgtttcggt gcgggcgctg cgccgccccg acccggcggg
     3061 cccggtcacg ctgagcctgt cggacgggcg cgagctggag gtggacgagg tgctgttcgc
     3121 caccggccgg gtccccaaca ccgacgacat cgggctcgac accatcggtc tcacccccgg
     3181 cgactggctc gaggtgaccg acagctgtca ggtccgcggc ccgcacgagg actggctgtt
     3241 cgccctcggc gacgccaacc accgtgcgct gctcacccat cagggcaaat accaggcccg
     3301 catagtcggc aacgtgctcg ccgcccgcgc ggcaggccaa cccgtgcgga gcgacccgtg
     3361 gagcccccac accgcgaccg ccgacacccg cgcggtcccc caggtcgtct tcaccgaccc
     3421 cgaggccgca ggggtgggcc tgaccgccga acaggccgag cgcgccggac accgcacccg
     3481 cgtggtggac atcgacctgg gcgcggtagc gggcgccgcc ttgtacgccg acggctaccg
     3541 aggccaagcc cgaatggtcg tcgaccaaga cgaaaaccgc ctcctgggcg taactttcgt
     3601 aggccccggc gtcgccgaac tcatcacctc ggccaccatc gccgtagccg ccgaagtccc
     3661 cctcgaccgc ctctggcacg cagtcccctg cttcccgacc atcagcgagg tctggctacg
     3721 cctcctcgag gcataccgcg gctgaccacg ggtcgacccc ctcgctagca cgtagtcgaa
     3781 gactctcctc gtcattccgg cgtgctgata gccggaaccc accctgccgc aagtgatccc
     3841 ggccaaaagc acgccgggat cacgagtggg gcttccgtcg atgatcacga gtggggcttt
     3901 ccgtcgatgc gcttaggtcc cggcgtgctg cccatcgggt cccgatacgt cgcaccctct
     3961 ggtcccggcg tgcttttggt ggtcccggcg tgcttttggc cgggaccgtg acgtgcgcca
     4021 taccaaacta tattgcgcac aatataattt ggtcatacag tattgaacgt gaccgatccg
     4081 ttggcgctcg agcagcaggt gtgcttcccg ctctatgcgg tttcccgggc tatgacctcg
     4141 gtgtaccggc cgaagctgga ggcgttgggt cttacttatc cgcagtatct ggtgatgctg
     4201 gtgctgtggg agcacgatga tcgcagtgtc ggtgagttgt gctcggcgct ggcgctggac
     4261 tccgggacgt tgtcgccgct gctgaagcgg ctcgaggggg ccgggtatgt ggaacgggcg
     4321 cgggcggtgg atgacgagcg gcgggtggat gttcgcctga ccgagcgggg gcgcgagctg
     4381 cgggagcggg cgtgcgtcat tccggccgag atggccgagg ccaccgggct gtcactggaa
     4441 gaactcggtg cgctgcggga gacgctgctg cgcatgaacc gggcgctggt cgcccacact
     4501 cgttcgaagg agaagtgaga tgacggttct gtacaccgcg gaggcgctgg ccaccggcga
     4561 cggccgcaac gggcacgccc gcaccaccga cggcaaggtc gatgtggcgc tgtcgattcc
     4621 gaaggaaatg ggcggcaccg gcgagggcac caaccccgag cagctgttcg ccgcgggcta
     4681 cgccgcgtgc ttccactccg cgctgcggct ggtcgcccgc caggccgggg cgaacgtcga
     4741 cgattccgcg gtcggcgcga aggtcggcat cggccccgac gagaccggcg gcttccggct
     4801 cgaggtcacc ctcgaggtgt cgctgccgca cctggcccac gagcaggccc aggacctggc
     4861 cgaccgcgcc caccaggtgt gcccgtattc caatgccacc cgcggcaata tcgacgtcca
     4921 cgtcgtcgtc gccgaagact gagaggagcc gagcatgcgt gcggtagttg tcgagaactt
     4981 cggcgagccc aaggacgtgc tgaccccggc cgagcggccg acgcccgagc cgggcccggg
     5041 ccaggtgcga atcgccatga cgctcagccc gattcacaat cacgatctcg cgatcgtgcg
     5101 cggcgtgtac ggctacaagc cgccgctgcc gaccgtgccc ggcaccgagg cggtcggccg
     5161 cgtcgacgcc gtcggcccgg acgtgaccgg cgtgagcgcc gggcagcggg tcgtcgtgcg
     5221 cggcgcgcag ggcgcctggg cggaatactt cctggccgag gcggcgcaac tgattccggt
     5281 gcccgacacc atccccgacg agaccgcggc ccagctgctg tccatgccgc tgagcgcgct
     5341 gatcctgctc gacgatctgc gggtgcgggc gggcgactgg atcgcggtca acgccgccaa
     5401 cggcgcggtg ggccggttgc tcaacgcgct ggccgccgag cgcggcgtgc gggtgctgaa
     5461 cctggtgcgg agcgaggcgg cggtgacggc gctgcgggca tcgggcgccg aggcggtcgt
     5521 gagcaccgaa gccgcggact ggcgcgacgc cgtcaccgcg gcgaccggcg gcgcgcccat
     5581 cgtgcgggtg atcgaccagg tgggcggccc cgccggtggc gagctgctga cgctactggc
     5641 cccgggcggt gagctcatct ccttcggcgc gatgtccggt gagcgcctgg tcctcaatac
     5701 cggcgccctg atcttcaaac aggccgtggt gaagggcttc tgggccgcgc ggcgcatgga
     5761 ggagatcgga cgggaggcca ccgtccgact catcggtgag ctggtggccg cggccgaacg
     5821 cggcgtcctc cggctcgaca tcgaggccgc ctacccgctc gccgacgccg ccgaggcggc
     5881 cgccgcgagc gaacggcccg gccgcaacgc aaagatcgcg ctgcgtcccg cgtaaaccgt
     5941 tgctacgccg cggcgttgga ctggatcagc gcgtgtttcc cactgctgcg ccagttctcg
     6001 cccgcggcgt ccagcgtgcg gacctgctcg gcgctgagcc ccaccaccac atcggatttc
     6061 agcgtgcgca atgcggtgac gggcgtgggg aaatagcgca ccagctcggc gaacggtgtc
     6121 gtcggcggcc agtagcggtc gccgacgagc cgccggtagt tcagatcgcc cttgaggatc
     6181 gtcattgccg caccggtgag ctcgtcggtc aggtcggtgg gcatgtcgtg aaaatgcagt
     6241 ggggcgcaga agaattcgtg tgcgcgcacg accaggcgat cgtccgccat cgcctgccac
     6301 aatcgctgcc cgacccgctg cgcctgtggg gtatcggcgt cgcgcagccg ccgcagcgcc
     6361 gcgagcaggt cggtcatggt cgcatcggag acgtagtacg ggtgcggttt gacgtgcacg
     6421 accacccggc ccgccaggtt ttcggtcaga aggtggtcgg ccagtacgag atccggtagc
     6481 agttcgcggc ccgcattgtc ggcgatcagc gccaccgtcg ccccgggtgt tcgctccagc
     6541 gccgcccaca gcgccgcgct gtcgtccacg agcagccggg tgtccaccgt gcccgattcg
     6601 gcggtgagcc gaaaacccaa gtccgcctgg ttaccccaca gcgccgagcg cagcagcgcg
     6661 tcccggatgc tgtcgatcag ccggtccacg agagtgtcca gcgcggccag ctcgtcgtcc
     6721 acggcgcgac cgtacagctc cgcggccttg gtcggcccga acggatcgat acgccgccac
     6781 ggcccctccc cgaagtagcc caccgcgtcg agaagccgcc ggtagaaata actttcggcc
     6841 cacaggaacg gtacctcgcc ccacggccgc gaccacatct cgcgccccca ctccagccac
     6901 ggcgcgaccc gctcaccacc cggctcgggc ggccgcaccg tcccgctcgt gctctccgcc
     6961 agcaactccc gcagccccgc ccgcgcggcc gggccatacg gatgcgcacc gatcacctgc
     7021 tcgatcagcc tcggatgacg ctcatggaac acgctgtgcg gaaaggtccc cggaaccccg
     7081 gcgagaatcg gcggcacatc ggtcatggtg acgatcctgt cacgggctgc ggattcgctg
     7141 ataaggcgcc cgtgaatgcc caggtcgcca ggacgattca tcctgtcggc aagtggattc
     7201 gtgatagcca ccggcgtgga taacggtggg tggatcacgg tggcgcggta tcgccggaat
     7261 ccgggagagc tccgggggac gtcactaccc gtgcccgaac gatcagcaga acgcgatcgc
     7321 cctgtgcggg cagtgacccc gtcagatttc ctaggccgcc ggaattcggt cacgatgcgc
     7381 gcggcgacgc cgtccaccga tgggtgaatg ccacgcatga gccactgcgt cggatttacc
     7441 cgaacccctc gctcggctct agctgggcca gactatccgc ccgcgctagg cgggccgggg
     7501 ccgcgcctag cgcgggcgtg gtgcccgggc gtggtgcggg gtatgtgagg cgcgtcacta
     7561 aatgtgggaa tgtgctgtgt ggtgagaagg tcggttggtt gtggtgtgtg gtgggagtgg
     7621 gtgcggcgca atcccaccac acaccacaac caaccgacct tctcaccaca cagcacattc
     7681 ccacatttag tgacgcgcct cacatacccc gcaccacgcc cgcgctaggc gcggccccgg
     7741 cccgcctagc gcgggcggat agtctggccc agctagagcc gagcgagggg ttcgggtaaa
     7801 tccgacgcag tggctcatgc gtggcattca cccatcggtg gacggcgtcg ccgcgcgcat
     7861 cgtgaccgaa ttccggcggc ctaggaaatc tgacggggtc actgcccgca cagggcgatc
     7921 gcgttctgct gatcgttcgg gcacgggtag tgacgtcccc cggagctctc ccggattccg
     7981 gcgataccgc gccaccgtga tccacccacc gttatccacg ccggtggcta tcacgaatcc
     8041 acttgccgac aggatgaatc gtcctggcga cctgggcatt cacgggcgcc ttatcagcga
     8101 atccgcagcc cgtgacagga tcgtcaccat gaccgatgtg ccgccgattc tcgccggggt
     8161 tccggggacc tttccgcaca gcgtgttcca tgagcgtcat ccgaggctga tcgagcaggt
     8221 gatcggtgcg catccgtatg gcccggccgc gcgggccgcc cgcaccgccg ccgcgaccgc
     8281 gtcggcgctc ggctctagct gggccagact atccgcccgc gcggccgggc catacggatg
     8341 cgcaccgatc acctgctcga tcagcctcgg atgacgctca tggaacacgc tgtgcggaaa
     8401 ggtccccgga accccggcga gaatcggcgg cacatcggtc atggtgacga tcctgtcacg
     8461 ggctgcggat tcacaggaat tgcacgggtg aatctggcac tgtccacgga aaatcacggt
     8521 ttactgaggt catgctgaca acagcatgaa cgggttcggt cccgacgagg aggtctggcc
     8581 gtgcagaatg cagtgacgac cgccattacc cggcgtgagc tggtgcggct catcggaatc
     8641 accggcgaat cggtcagcag gcgcggcctg cgctcgatca atgccgatgc cgtcgcgacg
     8701 gccaccgatc cggtggcggg ccgcaccgcg ttcgtcgtcg cggatggggt gggcgaccac
     8761 ctgctggccg cgcgggccgc ccgcaccgcc gccgcgaccg ccgcccgcgt cggcgcgcac
     8821 gacggcgcac tcgcgggaat cgttgcggca caggcgcaat tgctccgtga attcccggag
     8881 ccgagcgccg acgcggtcgc ggtggtggcg gtgctgccca cccccgagcg cccggacgcg
     8941 ccgaccgaga tcgcctgggt cggcgactgc cgcgcctacc gctggaacgg gcgggtgctg
     9001 catcagatca ccgtcgatca caccgtcgcc gaatacttcc gtgcgcgcgg ccgcatcgcc
     9061 gcgccgcgca tgagccacct ggtcaccacc tcggtgcgca cggtccgccc gggcgggatc
     9121 ggattcgcga gcaccgggtc gagccggggc cgcctgctgc tgagcaccga cggcgtgcac
     9181 aagcgggtcg gcatggcgac cctcaaggaa ctgctgggcg gcggcgcggc gcccggcgcg
     9241 accgcggacg ccctggtcga cctggcatta cgcaccggcg gctcggacaa tgcgacagcc
     9301 ctcgtggtcg accaccagtg agtggcaagg tcgaagggat gtgagctcga tgcccagcac
     9361 gaacgacgac gaccgtgtcc ccgaaccgga gggcaaggcg ctcggtctgc cttacgactg
     9421 gcggcgtccg accgcacagc ggacccgctc ccgcatctgg aaccccgacg atccccgact
     9481 gttcaccccg aagagcttcg gctggggcta cggcctgaac ctctaccgcc tgttccactg
     9541 gcgtcggcgg ggctgacccg taggccgccg gagcccgaaa atcggtcgcg cacaacgggt
     9601 tcggcctcgt cgtgccgacc cggccgcgtc acggtcggcg gatcggcgga cggaccggta
     9661 gaaatggtcc cgatgggcgt gcacacggtc agcttcgacg acgcctactt ccgggactcg
     9721 cgggcggccg cagggacgct ggccgccggg ggccgattca ccggttcacc acgtcgtcgg
     9781 gaaccgaggg ctggttggtc accggtaatg aactcgcgcg cacggtgctc gcgcacccgg
     9841 atatagggaa gagcccggac gccatgatcg gtggtgaggt ggcggcgaat tcggtgccct
     9901 gcgccgggcc gccgcacggg gtatcaccat gcatgggcgc ggatccgccc gagcatgcgc
     9961 gattgcgcgg ggcggtggct gttgttggag agctggacgt tcatttcgtg agtaacggta
    10021 tcggtgcgac ggccgtggcg agggttcggc gtagcctcca cggtaatgcg cggaagattc
    10081 ggttcatcgc tgctgcggta cctcggaagt cgctgtgccc ggacaggtat gcgcgctgaa
    10141 gctcgatcgg gaggtcgaaa aaggcgtcga agaagagtgg aaggtcctgc ggtggtagtg
    10201 ccagtagtgc gcgtaatccc gctgctcgca acagatgtac cgcgtgggcg gacacgggcc
    10261 agatcgattc cccggccacg accgcatcgg acagagatag cgacgtggcg acgctgtatc
    10321 cggtggccgg atgcagcaat ccgcccgcgg ctccgaatcg ggcgcggccg ggtcgaccgc
    10381 ccgttaccgg aaaccgtacc cgctcgaccg gctcgcttcc atcgagttcg attccgcgac
    10441 agcgcaatcg ggtgagcagc cggtcgcgca ggacggctcc gtcgagtgcg ggccgaccgg
    10501 cgaggcaggt ctcctctagg agcatagcgt ccgcgcggag ggggaccgcg tagaggaagg
    10561 agcggggatc gtccggaccg gcgccgttgt ccggacgcca atccatgaac agtgtttcgc
    10621 cccaggatcg ccgaggaacc accacgccgt acgcggtctg ctcggcgcgg gcgggggagc
    10681 gggctacacc gcgcgcatcg atcacgcgcc gggcggtgag ggtcgtgcct gtcgaaagtc
    10741 gaacggaggc agggctttcg gcggtccggt cgatatcgat cacgtggtcg cgaacgaccc
    10801 gtgcaccggc cacggtcagt gaatcctgta gcgccccacc ttcgaacacc acatacgctc
    10861 gctcgatctc gaatcgccga ctgccccatg ccgccaaacg ccctgcggtc gtccccaccg
    10921 gcgcgaccca ccccggcagc tcgtcggccc acgcgccgta tgtggccacc cagcggcggt
    10981 ccggatgggg atcgacggcg gtgaccgaat atccgtgggc cagcgcgcga tgggtgaggg
    11041 cgcgcccggc ggggccgagt ccgcagacga gcaggtcggt ggtcacgggg agattggacc
    11101 agaccgcatt tcgcgtcccg cgcgcggtgt cgggtagcct tcggcactga gcccgggggg
    11161 aacgaccgcg gagggcgctg ggtgcctcgg gtgcggaagg tggcacgcac gatgagttat
    11221 ccccccggct cggggcccta cggtcagcag ccccaggatg cgcccggccg gggccaacac
    11281 cccggcggcc agccgcagcc gggatggaac gcccagcaat ccgactggga gcagccacaa
    11341 tccgcgtgga accagcagca ggcagcgagt cagccgcagg cgacacagca acaggcggcg
    11401 tggggtggcc agcaggtcgt ggatcagcag cagtctgcct ggggtgagca gcaggcggcg
    11461 ggtctgccgc aggcgacgca gcagcagcgg caggcggtgt gggggcagcc gcaggtagcg
    11521 cagcagcagg tggtctgggg tgaccagcag gcagtcggtc agcagcaatc cgtttcgggt
    11581 gagcagcaag tagcggggca gcagcgaccc ggctggggtg agcagcaggc ggtggggcag
    11641 cagcaacccg cttggggtga ccagcaggca gcgggtcagc agcaatccgc ttggggtgag
    11701 cagcaactag cggggcagca ggaacccggc tgggggcagc agcacgcggt ggggcagcag
    11761 caacccgcgt gggggcaaca gcaggccgtc tgggatcagc aacaaccgtc ggcatggggg
    11821 cagcagccgc ctcaggcatg ggggcagcct ggctatcccg gtggttactc gccgcagcca
    11881 cccaagaaga acaccggtct gatagtcggc atcgtcctcg gtgtggttgc cgtgctggtg
    11941 atcggtgtgg gcatcgttgt gcttgctacc cggcacaagt ccgacaatgc tgcctccgca
    12001 gcagcggcca ccccgtcatt ggtaccggcg acgacgagca gtaccgccac ggggcgcccg
    12061 accaccacac cgtcgagctc ggcatcgagt cgcttcagtt atcaggagca ggcgaaggat
    12121 tggaacttca agctcggcga tgtttcgctg catgcggatt gggtggcggg cgtcgaccat
    12181 cccacctgcg ccgatatcga gaagaacggg aagctgacgt ccctgggctg ccagtatgcg
    12241 gccgagatgg tgtaccgggc cgaggacggc gggctgatgc tcacgcagtt cgtcatgggg
    12301 atggccgatg ccgacaaggc gtcggccgcg tccggtcagt acagcgattc cgatctgaat
    12361 ctgcggccgg gcagctacat cgaccacttc gccgtcggta agtggaggga cgggtcccag
    12421 ggccaatacc tggttctcac catggtcacc gcgaccgatg ccgtcgacga ggacaccgcc
    12481 aagaaatacc tgcggtacct gcacgccgac atgctcggcg cactcacctt ccgctgaccg
    12541 gtccgggatc agataccgcc ggttgccagc agtccgccgt ccacccggac cacctcgccg
    12601 gtaatccagg acgcctgatc cgacacgagg aaggcgatga gggccgccac atcctccgga
    12661 ttgccgagac gcttgagcgg atacgcggcc gccgcggcgt cctcgtcggc ggagtacagc
    12721 gcatcggcga actttgtctt caccacaccc ggcgccaccg cattgacccg gatggtcggg
    12781 cccagctgcc aggccagttc ctcggtgagc cggatgagcg cggccttgga ggcaccgtag
    12841 gcggcgatca ccccggtcga ccgcagcccg gcgacgctgg cgacattcac caccgcgccg
    12901 ccgtgctcgc gcatccaccc cttgtacgcc tcctgcgtgt agcccagcgc ggccaccaca
    12961 ttcacatcga agatcttgcg caccgcgtcc aggtccgcgt ccatcagcgg cccgtacacc
    13021 ggattgatgc cggtgttgtt gatcaggatg tcgagcgagc cgagctcggc gaccgcggtc
    13081 gcgaccgcct ccgcgcgggc gtccgcatcg cccgaattgc ccgccaccgc aacgaccttg
    13141 ccgggatggc ccagtgcccg cagctcggcc gcggtctgct ccagcggctc gggcttgcgg
    13201 gcggtgatga gcacctgcgc gccgctcgcc agcagctccg cggcaaccgc cttgccgata
    13261 ccgcgactcg ccccggtgac cagggcgccc ttgcctttca gatccgcact catgacatcg
    13321 cacgttaccg gaatcacatc tgcggacaac cgatcccgcg ggcggtcccg gtcgttcgcc
    13381 cgggtaaaat gggtggttct tgtgtctcct tcggaggcac actcgggccg agacaggttc
    13441 gagtaccacc gccgtaccga ttcgttccga ggagacgttt gtgatcaccg cgaccgacct
    13501 ggaggtccgg gccggaatcc gcaccctgct caccgcgccg ggcccggcgc tgcgggtgca
    13561 ggccggtgat cggatcggac tggtgggccg caacggcgcg ggcaagacca ccacgctgcg
    13621 catcctcgcc ggtgagggcg agccctacgc gggcaaggtc atccgctccg gcgaaaccgg
    13681 ttatctccca caggatcccc gcgagggcaa cctcgacgtg ctcgcccgcg accgtgtgct
    13741 gtccgcgcgc ggcctggaca cgctgatccg cgatatggag aagcagcagg cgctgatggc
    13801 cgaggtcgcc gacgaggccg agcgggagaa ggcggtgcgc aagtacggcc gcctcgagga
    13861 ccgtttctcc gcgctcggcg gctacgtcgc cgagagcgag gccgcccgca tctgccacag
    13921 cctcggcctg cccgaccggg tgctgggcca ggcgctacgc acgctgtcgg gtggtcagcg
    13981 ccgccgaatc gagttggcgc gcatcctgtt cgccgcctcc gacggcagcg gcggcaagtc
    14041 cgacaccacg ctgctgctcg acgagccgac caaccacctc gacgccgact ccatcacctg
    14101 gctgcgcggc ttcctgcaga gccacgacgg cggcctcatc gtgatcagcc acgatgtcga
    14161 gctgctcgag gccgtggtga accgggtgtg gttcctcgac gccgtgcgcg gcgaggccga
    14221 cgtctacaac atgggctgga agaagtatct cgacgcccgc gccaccgacg agcagcgccg
    14281 ccgccgcgag cgcgccaacg ccgagaagaa ggcgtccgcg ctcaaggccc aggccgccaa
    14341 gatgggcgcg aaggcgacga aagccgttgc ggcacagaac atggtcaagc gggccgagcg
    14401 cctgctcgcc gaggccgacg aggtccgggt gtccgacaag gtggcgcgca tcaagttccc
    14461 gcagcccgcc gcctgcggca agacgccgct gatggccgag aacctcacca aggtgtacgg
    14521 ctcgctggag atcttcaccg gcgtcgacct ggccatcgac cgcggcagcc gggtggtggt
    14581 gctgggcctc aacggcgcgg gcaagaccac gctgctgcgc atgctggccg gtgtcgaaca
    14641 acccaccgcc ggtggcctgg tgcccggcca cggcctcaag atcgggtact tcgcgcagga
    14701 acacgacacc ctcgacgaca cggcgacggt gtgggagaac attcgccacg ccgcccccga
    14761 tgccggtgaa caggatctgc gcgggctgct gggcgcgttc atgttctccg gcccgcagct
    14821 cgagcagccc gcgggcacgc tgtccggcgg tgagaagacc cggctcgcgc tggcggggct
    14881 ggtgtcctcg gcggccaatg tgctgctgct cgacgagccg accaacaacc tcgaccccat
    14941 ctcgcgcgag caggtgctcg acgcgctgcg cagctacgcg ggcgcggtgg tgctggtgac
    15001 ccacgacccc ggcgccgccg aggcgctcaa cccggagcgg gtgatcatgc tgcccgacgg
    15061 caccgaggac cactggtcgc aggactacct ggagctcatc caattggcct gacggggtgc
    15121 ggatgtccgg ttcgtgcccg aaatccggtg gcggacggtg gcgtttgtga gaaatggtga
    15181 ggttcatcac aaagaggcgt tgatcaccga cggttgaatg cttagccttg aatgaggctg
    15241 cagggcgacc ggaggaagcc atgagtgaca ggcccgcaca ggggaagtcc acgttgggta
    15301 agggcacacg cgtcaccgga aagtcgcgcg accgtctcca aacccagctc aagaagcagt
    15361 acgaggcggg cgccagcatt cgctcgctgg cccgggagac cggccgctcg tacgggttca
    15421 tccacaacgt actggtggag tcgcatgtgc aactccgcag caggggtggg gcgaaccgcc
    15481 gcaagtcggc cgccaagtag gcggttcgac gcgccgagtc ccggtgggca cgttggcctt
    15541 tcgctcggga ggccgcgacc cgcgagttcg gcgcgccgac cggttcgcgg cgccacggca
    15601 taccgatctg tcggtcgtca cggtcgccgg ggaggcgatg ccgcgcgcgt tactgcccga
    15661 gcccgggcgc ggcgcgaaac cccttggtat cagcgccggt tcgccgtgcg ctcggcccac
    15721 cagcgcgggg cgtcgacgaa gtggttgtcg tattcctcct gggacgcacc gagatcggcg
    15781 agcgtggcct cgccgcgcgc gacccgctcc agcaggcgga agtacccgaa acgctgcacg
    15841 ccgggcatga gcgcgatgag aatgcgcgcg gcgctgtcgg gggccgcgcc gaaggcgtgc
    15901 ggcatgaact tgggcaccac cagcgcgccg cccgcgccga cggtcacgat ctcgtcgtcg
    15961 gccagcacct gcagctcgcc ctcgacgaca tagaacagct cgtcggagcg cgtgtgatag
    16021 tgcggcgcag cgccatccgc gccgcgcgcc atgctgacct ccacggtgct cacaccgtgc
    16081 cccgcctcct cggagtcgat gagcagccgc acggtgacgg cctcggtgcg cagcgtctcg
    16141 gcgtcctgcg cccggcggac ggcgacgggc ttgcggggaa gggtggtcat ggccagctcc
    16201 gatggttcgg tgattgataa ttcgctgccg aactatatac cggcgaatag aatgctgtcc
    16261 atgcccgatc agcaacccga cgcgatcgac gcgatcgtga cccagtggcg gcgcgaacgc
    16321 cccgacctgg atctcgaggc catggccatc gtcggcaggc tcggccgcct gcacctggtc
    16381 gccgagcgcg ccgtcgaacg ggtcttcgcc gaccacggcc tgcagcgcgg cgagttcgat
    16441 gtgcttgcgg ccctgcgccg ttcgggcgag cccttcgagc tgaacccctc ggtgctggcc
    16501 gacaccctga tgctgtcgcg cgcgggcatg accggccgcc tggaccgcct ggagtccgcg
    16561 ggtctggtcc gccgcatcgc cgacgcgggc gatcgccgcg cggtgcgggt ggcgctcacc
    16621 gaatccggtc gcgccctggt ggatcgggtg gtggccgcgc acaccgccaa cgaaacccgg
    16681 ctgctgtcgg tgctttccgc ccaggaccgc gaccacctga accgcatcgc ccgaaccctg
    16741 ttggccgcct tggagtccga cccggctcgg tgagcgctat cgggtgacgg tgatgtcgcc
    16801 gtggagttcg atccgggtcg gtgagtgcca tcgggtgacg gtggcgtcgc cgtggagttc
    16861 gatccgggtc ggtgagtgct atcgggtgac ggtggcgtcg ccgtggacga ggaatttcgc
    16921 gaggctggcg aagatcggga ggcccgtctt gatctccagg taggcgaact ggccctgcgg
    16981 attcacctcc aggaagtagt actccccgtc gcggccgact cgcaggtcca ggacgccgaa
    17041 ggtcaggccc agcgcgccca tgagggtggt gagggccttg ctgatcgcgg cgggcagccg
    17101 ctcgggggtg aacgcgaccg aggcgtccag ccgcgaatcc acccgtccca caccggcttg
    17161 cgagtcgatg cgcaccgccc actccacgcc gtcgatccac accacccgca gatcgcagtc
    17221 ggcgtcgata tagtcctgga aggtggtcgg cgcggagcgg atggtggcca gccggtcgaa
    17281 gtcggcgggg gtgaccagcc gggtctcggc gaattcggtg cggccggtgc cggtgcgctt
    17341 gtagacgacc gcgccgggcc gggattcgat gaagctgcgc gcctcgtcgg gatcgttggt
    17401 gatcagcgtt tccgggatcg ggaaaccgga gcggcgcgcg gtctcgagct gcacgatctt
    17461 gcggcccgcg gtgcggtcgg cgcccggatc gttcacccac agcgccggta tcgaccacag
    17521 caggccctgc aggaagccgt cgcattcggc ctgccggtag tcgtcgtcgg cgcggcgcac
    17581 cccgccgggc acccggcacg gatgcgggcg gcgccaccac acggcggtga catcgtcgag
    17641 cccggcgagc ggcgcgaggg cgcgcgcggt tccggcccgg tccagccgga aacttccgct
    17701 gtgcgagggg aagtcgcgca tatcgaggcg tatcggcgtg agcccgtgct gttttcgcag
    17761 cgtggcggcc atcgcgtcgg cgtgcaggtc ctcggattcg gtgacgatga gcaccggacc
    17821 cgccgcgcgg acggccatgg gcgatcctca gtccagactg tcgcaggcga cgccgtcgtc
    17881 gctgcggccg gaggttctgg tctgacagaa ggtccaggtc gcgccgccgg taccggtgac
    17941 ctcgggcagg cgcaggccgc gggcccaccg ctcggtgagc gtgcgcagct gctcgtcgcc
    18001 gcgggccgga gagggccgct gcggcaaggt catcgggcgc tcggtgagct cgatgcgcag
    18061 ccgctgcgtg aaatcggcgg tggcgccggg gcgaatccgc accagcaccg cgcgaccgtc
    18121 cggcgcggcg tcgaattcgc ctgtggcgca gtcgtcgata tccaggacat cggcccggtc
    18181 gaaggtccag gtgccttcgg tgacccggac gctgatagcc cgatccgact cggccaccag
    18241 gcggcccggc agggcgggcg cggcctcgag ggtgcccgag cgcgggcgca acacatcggt
    18301 catgggctgg tctccgatct gctcgcggtt agccacagaa gccgaacgtg ctctggatca
    18361 tagcccgccg ggcccgcgcg ccggtccgca acgagagatt tccatcgtct cggcaaagtc
    18421 tcggcatgcg cgcggaaaac cctctccgcg agaccaattc ggttgaccgc tcaaggcgtc
    18481 acagaccgag cagttcccgg gactcggcga gctcgatgaa gcgctcgatc ggatccggga
    18541 cgagtttgcg cgcgctcaga tccagcagtc ccaatgtcac cgtgaattcg gccgacacgg
    18601 tgccgtcgag cttgacgatc tgctggctca tccggaagat cttgccctcg gtccattcga
    18661 aggcgctggt cacggtgacc tcgtcgccga tgtgcagttc gcgcaggtat ttgacggtgg
    18721 actccagcac caccgggccc aggcccgcgg cggccagctt gtcgggggtc agcccggccg
    18781 cgcgcatgtt ctcccagcgc gcgtgctcgg cgtactggtg gtagaccgcc tgattcaggt
    18841 ggccgttcac gtcgatttcg tagccgcgga cggtgacggg cacggagaag gtcataacct
    18901 ggcgaaccac cggcgcatgt ctgctatttc cgatttcgcc gtgtggtcgc tcacgcccgc
    18961 gcgcccggac cggaaattca cggcccggca tcggctcgtt ctcggtcgca taccggactg
    19021 ggcgttgggt atttccagga tctacctttg aggatgggag gggattctcg atgaggagaa
    19081 cccgatgatc gatgtcatca cgttccgagg tgtcggcgag ccccgcgacg cggacggtga
    19141 cccggcgggc atgcagcagg ccgtgacgga tctgctggat ccgagattct tccacggttt
    19201 cgaaccggac tggcccgcct cgatcgggcc cgacccggat ctgtgggggc cgtcgctgga
    19261 cacctcggtg cgcgacggca tcgccgccgg ggtccaagcc atccaggact caccgaatgt
    19321 gtgtgggctg ctgagctatt cgctcggcgg cctgtgcgtg agcggaatcc tcgagggcat
    19381 gcggtcgggg gagtacacca atgccgacgg cagcccgctg caggtcgcgt tcgcggtgaa
    19441 tatcgccaat ccggttcggg cggcgggaga ttcggtgaac aacctgtgcc cggcgaatac
    19501 cttcgggctg cacggccagc acgggccgtg gcccgcgtcg gtgcaggtgc gcgagtacgc
    19561 caaccccggc gacatcatca ccgcctcccc ggccgattcc ccgctgcaca tcatcgacgt
    19621 ggggatctca ccgttctcgt tcgtcgaggg cgcgcgcttc ggcaacgtca cctacctgat
    19681 cttccaggag ctgctgcgct tcctgctgct ggacccggtg gccaatctgc agcgctacgc
    19741 ggacgcggtg aacggcgtca tcggctacct gaccccctgg ccggacggtc agcacgtgct
    19801 ctacaacgcc caccccatac cgggcacgaa tgtcgtctgg acgacgcacg ccgccgagtg
    19861 gatcaacgcc accttcgggc actagtgctt gcggcgcacc gacgcctcca ccagatccag
    19921 gacggcctcc agattgtcgt tcgcatggcc cgaggcgatg cgggcgatga gaccgtccag
    19981 caccaggtcc aggtagccga gcaggacatc ggtcggcacg tcgtcgcgca gcgccccggc
    20041 ggccttgcgg cgctccagcc gcgccagcgt ggcggcggtc agctcggccg agcgctgcgt
    20101 ccatccggcg gcgaactccg ggtcggtgcg caaccggcgg gcgatctcga gtcgggtgcc
    20161 cagccagttg tattgcgaag ggttggcgag catttcgcgc atcacctgca cgatgccctg
    20221 gttggccgcc acctcggcca tccgctcggc gtcctcctgg gcgagggcca gaaacagcgc
    20281 gtccttgtcg cggaagtggt ggaagatcgc gccccgcgac agcccgatgg cctcctcgag
    20341 gcggcggacc gtcgcaccct cgtagccgta ttcggcgaaa cagcgccgcg ccccgtccaa
    20401 gatctggctg cgccgcgcgg caaggtggtc atcgctgacc ttgggcatgg gctcctccaa
    20461 acgggatggt gcgcgagacc cccgccccgg cttcgccgag gcgggggcca tctggctcag
    20521 gtccgggacg ggggtcttgc acgagacgac gagcggagat cctgatcccc cgaagcgaat
    20581 tcggggggtc aggacatgat cgcattcggg atcagctacg gatcatgttc cgcagtacgt
    20641 actgcagaat gccaccgttg cggtagtagt cggcctcacc gggggtgtcg atgcggacga
    20701 ccgcgtcgaa ggtgatcttg tctccgttct ccttggtggc ggtcaccttc agggtcttcg
    20761 gagtcacccc ctcgttcagc cgggtgatgc cctcgatgtc gaacacctcg gtgccgtcca
    20821 gcttcagcga cgcggccgac tcgccctccg ggaactgcag cgggatcacg cccatgccga
    20881 tgaggttgga gcggtggatg cgctcgaacg actcggtgat caccgcgcgc acgcccagca
    20941 ggctggtgcc cttggcggcc cagtcgcgcg aggaacccga accgtattcc ttgccgccca
    21001 gcacgaccag cggaatcctg gcctgctggt agttctgcga ggcgtcgtag atgaacgcct
    21061 gcgggccgcc gtcctgggtg aagtcg
//
