LOCUS       NZ_KV411304            21035 bp    DNA     linear   CON 12-FEB-2024
DEFINITION  Nocardia terpenica strain IFM 0406 scaffold2, whole genome shotgun
            sequence.
ACCESSION   NZ_KV411304
VERSION     NZ_KV411304.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardia terpenica
  ORGANISM  Nocardia terpenica
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 4638951)
  AUTHORS   Buchmann,A., Eitel,M., Koch,P., Schwarz,P.N., Stegmann,E.,
            Wohlleben,W., Wolanski,M., Krawiec,M., Zakrzewska-Czerwinska,J.,
            Mendez,C., Botas,A., Moris,F., Cortes,J. and Gross,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-APR-2016) Pharmaceutical Biology, University of
            Tuebingen, Auf der Morgenstelle 8, Tuebingen 72076, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 30-JUL-2014
            Assembly Method                   :: CLC NGS Cell v. 7.0.4
            Genome Coverage                   :: 118.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/12/2024 01:56:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,832
            CDSs (total)                      :: 8,760
            Genes (coding)                    :: 8,562
            CDSs (with protein)               :: 8,562
            Genes (RNA)                       :: 72
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 40 of 198
            Pseudo Genes (incomplete)         :: 174 of 198
            Pseudo Genes (internal stop)      :: 9 of 198
            Pseudo Genes (multiple problems)  :: 23 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:51:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 648270
            Orig. end                         :: 669305
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KV411304.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21035
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="5"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21035
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21035
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11035](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11035
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(334..349)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.01"
                     /tool="antismash"
     gene            complement(343..1137)
                     /locus_tag="AWN90_RS24030"
                     /old_locus_tag="AWN90_24065"
     CDS             complement(343..1137)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014985408.1"
                     /locus_tag="AWN90_RS24030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_24065"
                     /product="ABC transporter permease"
                     /protein_id="WP_067587222.1"
                     /transl_table=11
                     /translation="MRRGGERVVLGAARILVGVLVVAGWELGARCGALDVFFFSRPSDI
                     AVRLGAWFGSGSIWGHLRVTLTEAALALLLGGAAGMVAGFLLARARFAAAVLDPYLKMC
                     NALPRVVLAPIFLLWFGLGIWSKVALGVSLVLFIVFFNTYRGVREVDPVLVDSVRMLGA
                     SDARLLRHVLLPSALTWIFSSLHISIGFALVGAVVGEYLGASRGIGYLISQAEGTFDTT
                     GVFTGITVLCAVVLLVDLAVARAERRLLRWQPPRVTTSTGER"
     gene            complement(1121..1924)
                     /locus_tag="AWN90_RS24035"
                     /old_locus_tag="AWN90_24070"
     CDS             complement(1121..1924)
                     /EC_number="7.6.2.7"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014985409.1"
                     /locus_tag="AWN90_RS24035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_24070"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_067587224.1"
                     /transl_table=11
                     /translation="MADSNPAEVRLTDVTVSYPAAAGEHVAVSGLDLAVGRGRFVSIVG
                     PTGCGKSTVLNLVAGLLRPSSGTVLVDGQPLAGRNHRAGYLFQQDTLLPWQSVLDNVAL
                     GLRIRGVGKDERTARAREWLARVGLSGFEDAYPYQLSGGMRRRAAIARTWIVDPEILLM
                     DEPFGALDVHTRQLMETELLGLWTGSGKTVLFVTHDLDEAIALSDEVVLLSSGPGSRIV
                     GSYPIDLPRPRELLDIRTRPDFLRMHRSIWSDLRDEVVKTYAAGR"
     gene            1972..2145
                     /locus_tag="AWN90_RS46005"
     CDS             1972..2145
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS46005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_156674410.1"
                     /transl_table=11
                     /translation="MPGFPTRRQLAALADTTLAALADLGASMVGIPYPPPMDDPEEAAQ
                     RKARPDTVSGRA"
     gene            complement(2170..3384)
                     /gene="speD"
                     /locus_tag="AWN90_RS24040"
                     /old_locus_tag="AWN90_24075"
     CDS             complement(2170..3384)
                     /EC_number="4.1.1.50"
                     /GO_function="GO:0004014 - adenosylmethionine decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="speD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019927945.1"
                     /locus_tag="AWN90_RS24040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_24075"
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="WP_067587226.1"
                     /transl_table=11
                     /translation="MTAEFTGWHVLAEFGGVDAALCNDLERLETALRKSLVAAGVTICD
                     VVRKQFEPQGVTVLALLSESHASIHTYPESGDIFVDVFTCGSIGSGATKAVELLQQELS
                     PTAVNMEVVQRGHTARRIHEPVGNGLTRIWDLSEVIVDTRTPFQHMVIARTEQGVSLFS
                     DDDRQSTEFSQLTYHEAMLVPAYALAERLDRVLIIGSGEGVASQMSVAAGASHVDHVDI
                     DQLEVELCAKHLPYGYTEADLAAAVAHEGPIKMHYADGWDFLSRAQEQGVRYDVICIDL
                     PDERVEDAQHNRLYEEEFLTRCKSLLSDGGVLAAQAGCATMWRNETLKRSWQRFGELFD
                     TVVPYGSDEHEWTFLFGVAKPIADPVEAMTSRLSRLPYRAETVDERALVRGAIEPYALR
                     VAVPV"
     gene            complement(3393..4493)
                     /locus_tag="AWN90_RS24045"
                     /old_locus_tag="AWN90_24080"
     CDS             complement(3393..4493)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011210318.1"
                     /locus_tag="AWN90_RS24045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_24080"
                     /product="type III PLP-dependent enzyme"
                     /protein_id="WP_067587229.1"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 9.2e-45, bitscore:
                     150.9, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 3.2e-10,
                     bitscore: 38.2, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPESPCLVIDLQRVRDNYRALRSALPTARIRFAVKASPVPEIIRL
                     LADEGAEFDVASIGEIEQCLSLGVDPAVMCYGNPIKKATQIATAHTAGVRRYAFDTEDD
                     LERIAIHAPGAEVECRFLASAPQSQTPFGTKFGCAPGEAVRLMVRARDLGLRVVGPYFH
                     VGSQQLDPAAWRIGIEQAGAIAEALAVKDIPVSSVNIGGGLPISYADPAPELAELGAVI
                     AAAAARHLPEHADLVVEPGRALVGSAGVIHAEVVNVRMAPDGRRWVYLDVGRYNGMAET
                     ENEYIAYRIETLRDGDTRDEAVIAGPTCDGDDVLYQRTRVLLPTTLRAGDPVRILDTGA
                     YTASYSSVSFNGFPPLTVHVIGAERE"
     misc_feature    complement(3615..3617)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4682..7189)
                     /locus_tag="AWN90_RS24050"
                     /old_locus_tag="AWN90_24085"
     CDS             complement(4682..7189)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007296342.1"
                     /locus_tag="AWN90_RS24050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_24085"
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_067587232.1"
                     /transl_table=11
                     /translation="MQLSELIPDRVVPDVDADWLYESFAEWAAGQNLTLYPAQEEALLE
                     LMTGANVILATPTGSGKSLVALGAHFAALNRGQRSYYTAPIKALVSEKFFALCEVFGAE
                     RVGMVTGDAAVNPDAPIICATAEILANLALREGADADVGQVVMDEFHFYSDPDRGWAWQ
                     VPLLELPKAQFLLMSATLGEVDFFRGDLEQRTGRPTAIVAGTERPVPLLFSYRRTPITE
                     TLEELVTTNQSPVYVVHFTQAAALERAQALTSVNFASKAEKDAIAEAIGGFRFSSGFGK
                     TLSRLIRHGIGVHHAGMLPKYRRLVERLAQEGLLKVVCGTDTLGVGINVPIRTVLLTGL
                     TKFDGVRTRRLKAREFHQIAGRAGRAGYDTMGTVVVQAPEHEVENARLLAKAGDDPKKQ
                     RKVQRRKPPEGFVSWSEDTFDRLVAAAPEPMVSRFRVTNALLLNVIARRGNCFDAMRHL
                     LEDNHEPRPAQRKHILKAIRLYRALRDAGVVQQLDEPDEFGRRARLTVDLQRDFALDQP
                     LSPFALAALDLLDSDAPTYTLDVVSIIESTLEDPRQLLLAQQHRARGAAIAEMKADGID
                     YDERMELLEDITWPKPLAELIEPAFETYRAGHPWVSEFSPSPKAVVREMIERSLTFAEL
                     ISQYELARSEGMVLRYLADAYRALRRTVPESARTEELEDLTEWLGELVRQVDSSLLDEW
                     EQLTNPGAETDADQLAFGAETVRPISANERAFRVMVRNAVFRRVELAALHRWDALGELG
                     DGPDWETELAPYFAEYDAIGTGPNARGPRLFQLRQGPEFWRVRQVLDDPAGDHGWSVDA
                     VVDLAESDAAGEVVFDEIAVTAG"
     gene            complement(7235..8179)
                     /locus_tag="AWN90_RS24055"
                     /old_locus_tag="AWN90_24090"
     CDS             complement(7235..8179)
                     /GO_process="GO:0043248 - proteasome assembly [Evidence
                     IEA]"
                     /GO_process="GO:0051131 - chaperone-mediated protein
                     complex assembly [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019927941.1"
                     /locus_tag="AWN90_RS24055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_24090"
                     /product="PAC2 family protein"
                     /protein_id="WP_067587235.1"
                     /transl_table=11
                     /translation="MDYESRMYELEFPAPQLSSADGAGPVLVHGLEGFTDAGHAVRLAT
                     THLRESLEAELVASFDVDELLDYRSRRPLMTFKTDHFSDYADPELNLWALRDTAGTPFL
                     LLAGLEPDLRWEKFITAVRLLAEQLGVRRTIGLSAIPMAIPHTRPLGVTAHASDRDLIG
                     EHQRWPGELQVPGSASSLLEYRMAQHGHESIGFSVHVPHYLAQTAYPEAAQTLLENVAE
                     NAGLDLPLAALSESAARVREQVNEHIAGNAEVETVVHALERQYDSFVTAQERQSSLLAG
                     EADLPTGDELGAEFERFLAEQSGYGDDGFDDHR"
     misc_feature    complement(8378..8393)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: medium, score: 24.73"
                     /tool="antismash"
     gene            complement(8420..9202)
                     /locus_tag="AWN90_RS24060"
                     /old_locus_tag="AWN90_24095"
     CDS             complement(8420..9202)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016777.4"
                     /locus_tag="AWN90_RS24060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_24095"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_067595658.1"
                     /transl_table=11
                     /translation="MIIDAHSHVHDPVDRHIALLDEAGVDRAVVFATRPHPERATDLAS
                     LRAQMTALTAAVGGEVDPESYRIAWRELDVALAAHPDRFIGFGTVRLDLPGARIADYID
                     REVAGRGLRGIGELTPPPGRAAIIEPVLAAAADHGGLPVVVHGFDPTTADDLRTLAALA
                     DRYRTVPLVISQLGGTNWLTAIELVRDHPSLYLELSTASIIFAIRLAIAEIPDRALFGS
                     DAPYGDPVLARAAVERVTRAGEIRDRVLGGTLAQLLGR"
     misc_feature    9266..9280
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.19"
                     /tool="antismash"
     misc_feature    complement(9274..9286)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.45"
                     /tool="antismash"
     gene            9302..9664
                     /locus_tag="AWN90_RS24065"
                     /old_locus_tag="AWN90_24100"
     CDS             9302..9664
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003894857.1"
                     /locus_tag="AWN90_RS24065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_24100"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_067587238.1"
                     /transl_table=11
                     /translation="MLIGQLAERTGVSERQLRYYEQAGLLSSRRRDNGYRDYDDSAERT
                     VRQIRALLAAGLPVRLIRQVLPCALGDGSLRPCPGVLEALRGQLDRLDRRAAELADARQ
                     ILRHTIAVAENASVRP"
     misc_feature    complement(9730..9744)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.23"
                     /tool="antismash"
     gene            10001..11035
                     /locus_tag="AWN90_RS24070"
                     /old_locus_tag="AWN90_24105"
     CDS             10001..11035
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="AWN90_RS24070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_24105"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_082871305.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.9e-25, bitscore:
                     86.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAGDARVRRLAPESVDLTEFASLLTSELEHEYLLLLVPYGLEA
                     HAPSLAAGRLIRSRLAATAAGLLSDRLIRRCAALEMMHTSTLIHDDILDRGTVRRGLPT
                     LWKAVGRERALLIGNLVAARALAIAQADSAEAANVFLETWQRVNVAQLREVNERGRVKD
                     RAAHVGISIGKASAAMELGLVIGCMSSPGWPVDLTHLREAVREFGLGFQFADDVEDVRA
                     WLGASGPRRSKEAEFDIDLGNLTLPVTILAESAGVRFEPAGRRSVQVLRALSLEDWEPC
                     LQATFRIALDHLDRARWHLDRAEEFSGDRELARRVIEWADEMIESVRRKGLDMTLSELP
                     QVAR"
     misc_feature    10808..10810
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11032..11691
                     /locus_tag="AWN90_RS24075"
                     /old_locus_tag="AWN90_24110"
     CDS             11032..11691
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012905.4"
                     /locus_tag="AWN90_RS24075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_24110"
                     /product="HAD family hydrolase"
                     /protein_id="WP_067587245.1"
                     /sec_met_domain="HAD_2 (E-value: 1.1e-10, bitscore: 39.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRAVVFDIGECVVNTEREYRRWAQWLGVPAHTFAAAVGMALARG
                     FDEYHALRLVAPGIDPAAARARRAVEDELEYFTEDDLYPDVRPVLTALRARGVWTGIAG
                     NQTLETRDILRSLRLPCDLVATSEQWGVAKPDPAFFRRLVQHTPFEPGEILYVGDRLDN
                     DVRPAAAMGLHTALVRRGPWSLLQSPGAGDEPTLRIGELTELVGLLDRLDRDPLRV"
     gene            11768..12502
                     /locus_tag="AWN90_RS24080"
                     /old_locus_tag="AWN90_24115"
     CDS             11768..12502
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011210315.1"
                     /locus_tag="AWN90_RS24080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_24115"
                     /product="DUF5642 family protein"
                     /protein_id="WP_231951611.1"
                     /transl_table=11
                     /translation="MNEPDPPGRRHRLPTRRGGWRRALGCVALGCVLTACGSTVPGRPT
                     ADPSTPKNRHIGTALATLLPKQDQFPSPYAAVVPPAEQAAHIAGDLSGIPPGATVDPAD
                     CAPPQRPTGPDTSAVVVGTDAATRTTLTVLLTRVDTPLSTVRQQARGCGTVHVRRGPIT
                     DTVLTQPDPAPPVRADDTFALHRTVTGPATGPGLTRSMRTLLAQVGDVRIEATAMSYGD
                     GPSDPAGLDQVFVAAVEDVRAG"
     gene            12668..13906
                     /locus_tag="AWN90_RS24085"
                     /old_locus_tag="AWN90_24120"
     CDS             12668..13906
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025200.4"
                     /locus_tag="AWN90_RS24085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_24120"
                     /product="DUF4192 domain-containing protein"
                     /protein_id="WP_156674411.1"
                     /transl_table=11
                     /translation="MTASADRPADNDAARVTEDTAPGYSPPDLPRYDCARGESTPEPDW
                     RHPLLRVEQPAEFIAAIPALLGFVPERSLVVCLLQDTPERPGAVFLGAVARHDLDVSGC
                     GAWVRVAGQLAAICVQERAVGVVVLVVDDRASVTRAGRPGARASRHRDLIRALGGALRA
                     ADVTLADAWAAREIATGAPWWSLTDPERTGTQQDPSASPVTLAHVLDGRPIRSSRAELL
                     ATVEVDRELRDAVAAELEQAELTARRLYRRAVSRSAPGEYRRAALEMVLWQIAAVGSAA
                     PIPPDAVADVAVALRDSTVRDALFALAVGEHGRAAEELWTRLCRALDGPDRAEAATLLG
                     YSAYIRGDGPLAGVALEAALEADPSHGIAGLLETALRTGMHPQEMRKLARSGALAAAGL
                     GVDLGVDPAGWQS"
     gene            complement(13936..14916)
                     /gene="galE"
                     /locus_tag="AWN90_RS24090"
                     /old_locus_tag="AWN90_24125"
     CDS             complement(13936..14916)
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (61-171). E-value:
                     4.2e-08. Score: 24.5. Matches aSDomain:
                     nrpspksdomains_AWN90_RS24090_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019048002.1"
                     /locus_tag="AWN90_RS24090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_24125"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_067587248.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.2e-13, bitscore:
                     48.8, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.1e-05,
                     bitscore: 21.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLLVTGGAGYVGGVCAQVLIEDGHEVVVVDDLSTGNAEGVPNGA
                     KFVDGDIATVGVELIESESFDGVLHFAAQSLVGESVQQPEKYWYGNVVKTLALLEAMRR
                     TGTPRLVFSSTAAVYGEPEQVPITEDAPTRPTNPYGASKLAIDHAITSYAVAHGLAATS
                     LRYFNVAGAYGGLGENRVVETHLIPLVLQTALGHRESISVFGTDYPTADGTAIRDYIHI
                     RDLAQAHLLALAQSRPGAHRLFNLGSGTGFSVRQVISACERVTGRSIAAVNAPRRAGDP
                     AVLVASSERAVAELGWNPRHNDLDEIVADAWAFLRSLGDRAHSAR"
     aSDomain        complement(14404..14733)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AWN90_RS24090_NAD_binding_4.1"
                     /evalue="4.20E-08"
                     /label="AWN90_RS24090_NAD_binding_4.1"
                     /locus_tag="AWN90_RS24090"
                     /protein_end="171"
                     /protein_start="61"
                     /score="24.5"
                     /tool="antismash"
                     /translation="SESFDGVLHFAAQSLVGESVQQPEKYWYGNVVKTLALLEAMRRTG
                     TPRLVFSSTAAVYGEPEQVPITEDAPTRPTNPYGASKLAIDHAITSYAVAHGLAATSLR
                     YFNVAG"
     CDS_motif       complement(14575..14628)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AWN90_RS24090_0002"
                     /evalue="2.30E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="AWN90_RS24090"
                     /protein_end="114"
                     /protein_start="96"
                     /score="-2.1"
                     /tool="antismash"
                     /translation="ALLEAMRRTGTPRLVFSS"
     CDS_motif       complement(14845..14907)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AWN90_RS24090_0001"
                     /evalue="3.60E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="AWN90_RS24090"
                     /protein_end="24"
                     /protein_start="3"
                     /score="6.8"
                     /tool="antismash"
                     /translation="LVTGGAGYVGGVCAQVLIEDG"
     gene            complement(14920..15606)
                     /locus_tag="AWN90_RS24095"
                     /old_locus_tag="AWN90_24130"
     CDS             complement(14920..15606)
                     /GO_function="GO:0046914 - transition metal ion binding
                     [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016935055.1"
                     /locus_tag="AWN90_RS24095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_24130"
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="WP_067587251.1"
                     /transl_table=11
                     /translation="MKDLVDTTEMYLRTIYDLEEEGVVPLRARIAERLEQSGPTVSQTV
                     ARMERDGLLLVAGDRHLELTEKGRAMAVAVMRKHRLAERLLVDVIGLDWQNVHAEACRW
                     EHVMSEDVERRLVEVLNHPTTSPYGNPIPGLDELGVIPTSGAEEKLIRLSDLPSGQVSA
                     VVVRRLSEHIQTGPEIINQLREAGVVPDARVTVETKPGAVVISVPGHEGFELSDEMAHA
                     VQVKLV"
     misc_feature    15583..15598
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.4"
                     /tool="antismash"
     gene            15852..17096
                     /locus_tag="AWN90_RS24100"
                     /old_locus_tag="AWN90_24135"
     CDS             15852..17096
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019927936.1"
                     /locus_tag="AWN90_RS24100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_24135"
                     /product="acetoin utilization protein AcuC"
                     /protein_id="WP_067587254.1"
                     /transl_table=11
                     /translation="MARRPSSGATVVWTDRFLDYTWTPEHPMKPARLRLTMELARGLGL
                     LEGVETEAPGPAGEADLLRIHTPAYVEAVRGAVPPPPGTALPLAAPFGLGTTDDPIFPR
                     MHEAASVLVGGTLAAAEAIAAGRTRRAVSIAGGMHHAMPESAAGFCVYNDVAVAISWLL
                     DHGFDRIAYVDVDVHHGDGVQRAFYGDPRVLTVSLHQHPATLWPNTGWPEETGAGTAEG
                     TALNLTMLPGTRDAQWLRGFHAIVPGALAAFRPQLLVSQCGVDTHREDPLADLELSVDG
                     QRAAFLAMRELADRYAEGRWLAVGGGGYGVVRVVPRAWTHLLAAALDREIDPATAVPAD
                     WAERARAYAPSVEPPGTMGDGVDPAFDRWDGPGGTRETGDERTDRAQRALDTAVLATRR
                     ATFGLLGLDPEDPRD"
     gene            17089..19797
                     /locus_tag="AWN90_RS24105"
                     /old_locus_tag="AWN90_24140"
     CDS             17089..19797
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014986735.1"
                     /locus_tag="AWN90_RS24105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_24140"
                     /product="bifunctional GNAT family
                     N-acetyltransferase/acetate--CoA ligase family protein"
                     /protein_id="WP_067587257.1"
                     /transl_table=11
                     /translation="MTEPAAGHDSTPQDPPPPPQHWVADVLAADGGVVRVRPIAPADAE
                     ALQRFHAGLSDRTRYLRYFGPYPRMTPKDLYRTTHVDYRDRVGLVVELGAVIIAVGRYE
                     LLPDREGPRAAEVAFVVADEHQGRGLGSILLEHLAGAAAENGIETFVAEVLAENNAMVT
                     VFRDAGYQVQRSRDGSVLHLEFAIDPTEALLSVRDSRERASEARSVGNLLAPRSVAVIG
                     ATPSSGRVGGAVLANLLSGVFQGPVFPVNPNRSSVRGVRAYPTVREVPDEVDLAVVAVP
                     AGEIKSVLDDCMAKGVKGLVVLTAGFSEIGPAGYAAERDLVAAARGHGMRVVGPSALGI
                     ANTDPAVSMNATLAPVLPGRGRIGFFCQSGPLGAAILGEAAARKLGLSTFVSAGNRADV
                     SGNDMLQYWDTDPDTDVVLLYLETFGNPRKFSRIARRVARGKPIVAVSSGRNATHTAGA
                     LDPSHPLDRSLERDLFAQAGIVQVDTISELFDCAMLLAYQPLPPGPRLAVIGNSAALGW
                     LAVDAARGEGLTAGAPTDLGPQAEPADYLTAVAAAMDSSDVDAVIVIFAPPVPTSVTAY
                     AEAIRAGAGAGGKPVLTTFVADLGMPNLLATRGIGGSLERGSIPSYPDPERAARALARV
                     RRYADWRTRPVSPVRRPADVDTERARNLVGEWMRREPDGGWLADLEAVQLLDCYGIRVV
                     EFREVRDPEAAEAAAEELGYPVAAKATGELWRNRPDLTGVRLDLWRPSAVRRAYTDLAE
                     VSGNEVVHIQKMATKGVGCVLRVQDDPSFGSVISFGLSGTIIDLLGDRVYRALPLTEDE
                     SAELIDAPRAAPLLDGKAGVAGRTIGEPVDKRALSELARRISALCDDLPEIRELAVEPA
                     LASARGAAILYARVRIGPEPSRFDIGPRRLA"
ORIGIN
        1 ccgcgagcac caactcgggc cggtccagca tcgtcacgaa cgaggtcacc gcgcggttct
       61 tggcctgcat ctgaatggtg tggtcgtagt acccggcaac gacgtcgacg ctgccaccct
      121 gcagcgcctg cagggccttg gacccgccct gcatgtcctc gatgcggacg tcgacgcccg
      181 cccggtcgaa gaagccgagc cgctgggcca gggtcagcgg gaggtacacc ggcagcgact
      241 ggccgccgac gccgatcgta atgtggtggc cgccaccgga tttctgcgcg cagccgacca
      301 gggccaccag tgccagcgcc agcagtgcgg cgatcttcgc tctcatcgtt ctcccgtgct
      361 tgtcgtgact cgagggggtt gccaccgcag caggcggcgt tcggcgcgcg cgacggcgag
      421 gtcgacgagc agcaccaccg cgcacagcac ggtgatcccg gtgaacacgc cggtggtgtc
      481 gaaggtgccc tccgcctgcg agatcagata gccgatcccg cgcgaggcgc ccaggtactc
      541 gccgacgacg gcgcccacca gcgcgaaacc gatgctgatg tgcaggctgg agaagatcca
      601 ggtgagcgcc gagggcagca gcacgtgccg cagcagccgg gcatcgctcg cgcccagcat
      661 gcggacgctg tccacgagca ccggatcgac ctcgcgcaca ccgcgatagg tgttgaagaa
      721 gacgatgaac aacaccaggc tcacccccag cgcgaccttc gaccagatgc ccagcccgaa
      781 ccacagcaga aagatcggcg ccagcaccac ccgcggcagc gcattgcaca tcttcagata
      841 gggatcgagc acggcggcgg cgaatcgcgc acgggccagc aggaatccgg cgaccatgcc
      901 cgccgcgccg cccaggagca gggccagcgc cgcctcggtc agcgtgaccc gcagatggcc
      961 ccagatcgac cccgaaccga accaggcgcc gagccggacc gcgatatcgc tgggccggga
     1021 gaagaagaac acgtcgagcg cgccgcagcg cgcccccagc tcccatccgg cgacgacgag
     1081 cacgcccacc aggatccggg ccgcgcccag cacgacgcgc tcaccgcccc gccgcatagg
     1141 ttttcaccac ctcgtcgcgc agatccgacc agatggagcg gtgcatgcgc aggaagtcgg
     1201 gccgggtgcg aatgtcgagc agctcgcgcg ggcgcggcag gtcgatcgga tagctgccga
     1261 cgatccggct gcccggcccg gacgacagca gcaccacctc gtcggacagg gcgatggcct
     1321 cgtcgagatc gtgggtcacg aacagcacgg tcttgccgct gccggtccac agccccagca
     1381 gctcggtctc catcagctgc cgggtgtgga cgtcgagcgc gccgaacggc tcgtccatga
     1441 gcaggatctc cgggtccacg atccaggtcc gggcgatggc ggcccgccgg cgcatgccgc
     1501 cggacagctg atacggatag gcgtcctcga accccgacag gcccacccgg gcgagccatt
     1561 cgcgcgcgcg ggcggtccgc tcgtccttgc cgacgccgcg gatgcgcagc ccgagcgcca
     1621 cattgtccag cacgctctgc cagggcagca gggtgtcctg ctgaaacagg tagcccgccc
     1681 ggtgattacg gcccgccagc ggctgcccgt cgaccagcac cgtgccgctc gagggccgca
     1741 gcaggcccgc cacgagattg agcacggtcg acttgccgca cccggtcggg cccacgatcg
     1801 acacgaatcg gccccggccc accgcgaggt ccagcccgga taccgccaca tgttccccgg
     1861 cggcggccgg atacgacacg gtcacgtccg tcagccgcac ctcggcgggg ttgctgtctg
     1921 ccacggcaat gtactatata cgtacatact tagtatgtca ggagagagtg catgcccgga
     1981 ttcccgacga gacgacagct cgccgccctg gccgacacga ccctcgcggc cctggccgac
     2041 ctcggcgcgt cgatggtcgg catcccgtat ccgccgccga tggacgaccc ggaagaggcg
     2101 gcgcagcgaa aagcccgtcc ggacacggtg tccggacggg cctgatcggt attcccctgt
     2161 gccacggtgt cagacgggga cggccacccg cagcgcgtag ggctcgatgg cgccgcgcac
     2221 cagggcgcgc tcgtcgacgg tctcggcgcg gtagggcagc cgggacagcc gcgacgtcat
     2281 cgcctcgacc gggtcggcga tcggcttggc gacgccgaac aggaacgtcc actcgtgctc
     2341 gtcggagccg taggggacga ccgtgtcgaa cagctcgccg aagcgctgcc aggagcgctt
     2401 cagggtttcg ttgcgccaca tggtcgcaca gcccgcctgg gccgccagca cgccgccgtc
     2461 ggagagcagc gacttgcagc gggtgaggaa ttcctcctcg tagaggcggt tgtgctgggc
     2521 gtcctcgacc cgctcgtcgg gcaggtcgat acagatgacg tcgtagcgca cgccctgctc
     2581 ctgcgcccgg gacaggaagt cccagccgtc ggcgtagtgc atcttgatcg ggccctcgtg
     2641 ggcgaccgcc gcggccagat cggcctcggt gtagccgtag ggcagatgct tggcgcacag
     2701 ctccacctcg agctgatcga tgtcgacgtg gtcgacgtgc gaggcgcccg ccgccaccga
     2761 catctggctc gccacgccct cgcccgagcc gatgatcagc acccggtcca gccgctcggc
     2821 cagcgcgtac gccgggacca gcatggcctc gtgataggtc agctgggaga actccgtgga
     2881 ctggcgatcg tcgtcggaga acagcgacac accctgctcg gtccgcgcga tcaccatgtg
     2941 ctggaacgga gttcgggtgt cgacgatgac ctcggacaga tcccagatcc gggtcagccc
     3001 gttgccgacc ggctcgtgga tccggcgggc ggtgtggccg cgctggacca cttccatgtt
     3061 cactgccgtc ggcgaaagtt cttgctgcag tagctctacc gccttggtgg cgccggaacc
     3121 gatactgccg caagtgaata cgtcgacgaa gatgtcaccg gactcggggt aggtgtgaat
     3181 cgaggcatgc gactccgaca gcagggcaag taccgtgacc ccctgcggct cgaactgttt
     3241 gcgcacgaca tcgcagatgg tcacccccgc ggcgaccaac gattttcgaa gtgcggtttc
     3301 gagtcgttcg aggtcgttgc agagggctgc gtcgacacca ccgaactcgg ccagcacatg
     3361 ccagccggtg aattctgccg tcatgggcaa actcactctc gctcagcgcc gatgacatgg
     3421 actgtcaaag gcggaaaacc gttgaaggac accgacgaat agctcgccgt ataggcgccg
     3481 gtatcgagga tccgaacggg atcaccggct cgcaacgtgg tcggtaggag gacccgcgtg
     3541 cgttgataga gtacatcgtc tccatcgcag gtcggaccgg ctatcaccgc ctcgtccctg
     3601 gtgtcaccgt ctcgtaaggt ttcgatccgg taggcgatgt actcgttctc ggtctcggcc
     3661 atgccgttgt agcggccgac atcgaggtat acccagcgcc gcccgtccgg cgccatgcgc
     3721 acgttcacga cctcggcgtg gatcaccccg gcgctgccca ccagggcgcg gccgggttcc
     3781 accaccagat cggcgtgctc cgggaggtgc cgggccgcgg cggcggcgat gacggcaccc
     3841 agttcggcca gctccggcgc cgggtcggcg tacgaaatcg gcagtccccc accgatattc
     3901 acggagctga ccggaatgtc cttgacggcc agcgcttccg cgatggcacc ggcctgttcg
     3961 ataccgatcc gccaggcggc cggatcgagt tgctgtgagc ccacatggaa atagggcccg
     4021 accacccgca gcccgagatc gcgcgcccgc accatcagcc gcaccgcctc gccgggcgcg
     4081 caaccgaatt tggtgccgaa gggcgtctgc gactgcggcg ccgaggccag gaaccggcac
     4141 tcgacctccg cgcccggggc gtggatcgcg atgcgctcca gatcgtcctc ggtgtcgaag
     4201 gcgtaccggc gcacgcccgc cgtgtgggcg gtggcgatct gggtggcctt cttgatcgga
     4261 ttgccgtagc acatgacagc cgggtcgacg cccaggctca ggcactgctc gatctcgccg
     4321 atgctggcga catcgaattc cgcaccctcg tcggcgagca gccggatgat ctccggcacc
     4381 ggagaagcct tgaccgcgaa tcgaattcgc gctgtgggta gggcggatcg gagtgcgcgg
     4441 tagttgtcgc gcacccgttg caggtcgatg acgaggcagg gcgactcggg cacgttggaa
     4501 ccgaacaatc taaggggact ctctttcttc cgggcagcct cccgctgcaa gccgagcgcg
     4561 agggtatcag cgggaagccg tgtgaaacga accggttgac gtcgtcttga tcacgcgcag
     4621 gcgcgtctac cgggttttcg acgcagaatt ttgacgacgg ttacgtcgtg acgggcggcg
     4681 ttcatcccgc cgtcaccgcg atctcatcga acaccacttc gccggcggcg tcggattcgg
     4741 cgaggtcgac cacggcgtcg acggaccagc cgtggtcgcc cgcgggatcg tcgagtacct
     4801 ggcgcacgcg ccagaattcg ggcccctgcc ggagctggaa caggcgcggg ccgcgcgcgt
     4861 tcgggccggt gccgatcgcg tcgtactcgg cgaagtaggg ggccagctcg gtctcccagt
     4921 cggggccgtc gccgagctcg ccgagggcgt cccagcggtg cagcgcggcc agctccacgc
     4981 gccggaatac ggcgttgcgc accatgactc ggaaggcgcg ctcgttggcg gagatcgggc
     5041 gcaccgtctc cgcgccgaac gccaactggt cggcatcggt ctccgcgccc ggattggtga
     5101 gctgctccca ctcgtcgagc aggctcgaat ccacttggcg cacaagctca cccagccact
     5161 cggtgaggtc ctcgagctcc tcggtgcggg ccgattcggg gaccgtgcgg cgcagcgcgc
     5221 gataggcgtc ggcgaggtag cgcagcacca tgccctcgga gcgggccagc tcgtactggc
     5281 tgatcagttc ggcgaaagtc agtgagcgct cgatcatttc gcgcaccacg gccttggggg
     5341 aggggctgaa ctccgacacc caggggtgcc cggcgcgata ggtctcgaag gccggttcga
     5401 tgagctcggc cagtggtttg ggccaggtga tgtcctcgag cagctccatg cgctcgtcgt
     5461 agtcgatgcc gtcggccttc atctccgcga tggcggcgcc gcgcgcccgg tgctgctggg
     5521 cgagcagcaa ctggcggggg tcctccagcg tggactcgat gatcgacacc acatcaagtg
     5581 tgtaggtcgg cgcgtcgctg tcaagtagat cgagcgcggc gagcgcgaac ggcgataggg
     5641 gttggtcgag cgcgaagtcg cgctgcaggt cgacggtgag ccgggcgcgg cggccgaact
     5701 cgtcgggttc gtcgagctgc tgcaccacac cggcgtcgcg cagcgcgcga tacaggcgga
     5761 tcgccttcag gatgtgcttg cgctgtgcgg gccggggctc gtggttgtcc tcgagcaggt
     5821 ggcgcatggc gtcgaagcag ttgccgcggc gcgcgatcac attgagcagc agggcattgg
     5881 tcacccggaa gcgcgacacc atcggctccg gtgcggcggc gaccagccgg tcgaaggtgt
     5941 cctcggacca ggacacgaag ccctccggcg gcttgcggcg ctgcaccttg cgctgctttt
     6001 tcggatcgtc gcccgccttc gcgagcaggc gcgcgttctc gacctcgtgc tcgggggcct
     6061 gcaccacgac cgtgcccatg gtgtcgtaac cggcgcggcc cgcccgcccg gcgatctgat
     6121 ggaattcgcg ggccttgagc cgccgggtgc gcacgccgtc gaacttggtg agcccggtca
     6181 gcagcaccgt gcggatgggc acgttgatgc cgacgccgag ggtgtcggtg ccgcacacca
     6241 ccttcagcag gccctcctgc gcgaggcgtt ccacgaggcg acggtacttg ggcagcatgc
     6301 ccgcgtggtg cacgccgatg ccgtgtcgga tcagccgcga cagcgtcttg ccgaaaccgc
     6361 tggagaagcg gaagccgccg atggcctcgg cgatggcgtc cttctcggcc ttgctggcga
     6421 agttgacgct ggtcagcgcc tgcgcgcgtt cgagggcggc ggcctgggtg aaatgcacga
     6481 cgtagacggg ggactggttg gtggtgacca gttcctcgag ggtttcggtg atcggggtgc
     6541 gccgatagga gaacagcagc ggcaccgggc gttcggtacc ggcaacgatc gcggtggggc
     6601 ggccggtgcg ctgctcgagg tcgccgcgga agaagtcgac ctcgccgagg gtcgccgaca
     6661 tgagcaggaa ctgcgccttc ggcagctcca gcagcggcac ctgccaggcc cagccgcggt
     6721 cggggtcgga gtagaagtgg aactcgtcca tcacgacctg gccgacatcg gcgtccgcac
     6781 cctcgcgcag cgccagattc gccaggatct cggcggtcgc gcagatgatc ggcgcgtccg
     6841 ggttgaccgc cgcgtcgccg gtcaccatgc cgacccgctc cgcgccgaac acctcgcaca
     6901 gcgcgaagaa cttctcgctg accagcgcct tgatcggagc cgtgtagtag ctgcgctgcc
     6961 cccgattgag cgcggcgaag tgcgcgccca gggccaccag ggatttaccg gagccggtcg
     7021 gggtcgcgag aatgacgttg gcgccggtca tcagctcgag cagcgcctcc tcctgcgccg
     7081 ggtacagcgt caggttctgg ccggcggccc attcggcgaa cgattcgtac aaccagtccg
     7141 cgtccacatc gggcacgaca cggtcgggaa tcagttcgga cagctgcacg tggctcgacc
     7201 ttaccggctg ccgcccggac tcctcacatc ggaactaccg gtgatcgtcg aatccgtcgt
     7261 cgccgtaacc ggactgctcg gcgaggaagc gctcgaactc ggcgccgagt tcgtcgccgg
     7321 tgggcaggtc ggcctcgccg gccagcaggc tggactggcg ctcctgcgcg gtgacgaagc
     7381 tgtcgtactg gcgctcgagc gcgtgcacca cggtctccac ctcggcatta ccggcgatgt
     7441 gctcgttgac ctgctcgcgc acccgggccg cggattcgct cagcgccgcc agcggcagat
     7501 ccagcccggc gttctcggcg acgttctcca gaagcgtctg tgccgcttcg ggatacgcgg
     7561 tctgggcgag gtagtgcggc acgtgcacgg agaagccgat cgactcgtgg ccgtgctggg
     7621 ccatgcggta ctccagcagc gaggacgcgc tgccgggcac ctgcagctca cccggccagc
     7681 gctggtgctc gccgatcagg tcgcggtcgc tggcgtgcgc ggtgacgccc agcgggcggg
     7741 tgtgcggaat cgccatcggg atcgcgctca ggccgatggt gcgccggacc cccagctgct
     7801 cggcgagtag tcgcaccgcg gtgatgaact tctcccagcg caggtccggt tccaggccgg
     7861 ccagcagcag gaacggcgtc cccgcggtgt cacgcagggc ccacaggttc agctccgggt
     7921 cggcgtagtc ggagaaatgg tcggtcttga aggtcatgag cggtcgccgg gagcggtagt
     7981 cgagcagctc gtccacatcg aacgaggcga ccagctcggc ctcgaggctc tcccgcaggt
     8041 gggtggtggc caggcgtacc gcgtggccgg cgtcggtgaa accctccagc ccgtgcacca
     8101 gcaccggacc cgcaccgtcc gcggacgaga gctggggagc gggaaactcc aactcgtaca
     8161 ttcgcgactc gtagtccatc gcgtactcct tccttcggtc caccacatcg gtccggcggg
     8221 caaccgccgc tgcccgaggt ggtctcgcgg accaccccca ttgtctctca tatcgccgac
     8281 gggccgttcc agccgggtgg gccgcacccg cacaacaaca ccgggttacc cgatcgacat
     8341 tcccgttcgc gggcgcgggg aaccgcgcac gccgcgccgt tcgctctcgg cgaaacccgc
     8401 cgcccgcccg gccgcatcgc tagcggccca gcagctgggc gagggttccg ccgaggacgc
     8461 ggtcgcggat ctcgcccgcg cgggtcaccc gttcgaccgc ggcgcgggcc aggacgggat
     8521 caccgtaggg tgcgtcggaa ccgaacaggg cgcgatcggg gatctcggcg atcgccagcc
     8581 ggatcgcgaa aatgatgctg gccgtggaca gttcgagata cagggacggg tggtcgcgga
     8641 ccagttcgat ggcggtgagc caattggtcc cacccagttg gctgatcacc agcgggaccg
     8701 tgcggtagcg gtcggcgagc gcggccagcg tccgcagatc gtcggcggta gtggggtcga
     8761 atccgtgcac gaccaccggc agtccgccgt gatcggccgc cgccgccagg accggctcga
     8821 tgatcgcggc ccggccgggt ggcggtgtca gctcaccgat tccgcgcagg ccgcgcccgg
     8881 ccacctcccg atcgatgtag tccgcgatcc gcgcgcccgg cagatccagc cggaccgtgc
     8941 cgaagccgat gaaccgatcc ggatgggccg cgagcgcgac atcgagctcc cgccaggcga
     9001 ttcgatacga ctccggatcg acctcgccgc ccaccgccgc ggtcagcgcg gtcatctgcg
     9061 cgcgcagcga ggccagatcg gtggcgcgct ccggatgcgg ccgggtggcg aacaccaccg
     9121 cgcggtccac gcccgcctcg tccagcagcg cgatatgacg gtccaccgga tcgtggacgt
     9181 ggctgtgtgc atcgatgatc aacgacatct ccctcgaact gctcccggcg accgcggaat
     9241 acggccgcca cggcagtgtt gaacgttgtc actgtgacaa ggtcaagatc gggggcaccg
     9301 catgctgatc gggcagttgg ccgagcgaac cggtgtcagc gagcggcagc tgcgctacta
     9361 cgaacaggcg ggactgctgt cgtcgcggcg gcgggacaac ggctaccgcg actacgacga
     9421 ctccgccgaa cggacggtcc ggcagatccg ggcactgctc gccgcgggac ttccggtgcg
     9481 gctgatccgg caggtgctgc cctgcgcgct gggcgacgga tcgctgcgcc cgtgtcccgg
     9541 ggtgctcgaa gcgctacgcg ggcaactgga tcggctcgat cgacgtgcgg ccgagttggc
     9601 cgatgcgcgg cagatcttgc ggcacactat tgcggttgcc gagaatgcga gtgtgcggcc
     9661 gtgaccaggc cggacgaccg accagcctgg tcaatgggcc tggtttttcc tgatctggtt
     9721 tgcgccatat agaactgatg tccagttcga cgtccccgcg attgtcggac tgtgcactgt
     9781 gcgggtcttc gtgtcgcact ggagattccg tcgcaggtcg ggcacggttt gatcgactcg
     9841 gcggcgcgcg ctcgccgacc atgatcgcgc acggaatgtc tgaatcaggc tgatttgaca
     9901 gtcacaaaag gattttgcat ctgtacgtgc aagcgtgtgc tgtaccgtta caagtggtct
     9961 ctttctaacc cccaactccc actgagccga ggcagccccg atgtcgacag ctggggacgc
    10021 gcgggtgcga cgactggcac ccgaaagcgt cgatctcacc gaattcgctt cgctactcac
    10081 gtccgaactc gaacacgaat atctgctcct gctggttccc tacggattgg aggcccatgc
    10141 gccctcgctc gcggccggaa ggctgatccg ctcccgcctg gccgccacgg cggcggggct
    10201 gctgtcggat cggctgatac ggcgttgtgc cgcactggaa atgatgcaca cctcaacgct
    10261 gatccacgac gacatcctcg accgcggcac cgtgcgccgg ggcctgccca cgttgtggaa
    10321 ggcggtcggc cgcgagcggg cgctgctgat cggaaacctc gtcgccgcca gggctttggc
    10381 gatcgcgcag gccgattccg ccgaggcggc gaacgtcttc ctggagacct ggcagcgggt
    10441 gaacgtggcc cagctgcgcg aggtgaacga acgcggacgt gtcaaggatc gggccgcgca
    10501 cgtcggcatc agcatcggca aggcctccgc cgcaatggaa ctcggcctgg tgatcggctg
    10561 catgtccagc ccgggctggc cggtcgacct cacccacctg cgcgaggccg tccgcgaatt
    10621 cggcctcggt ttccagttcg ccgacgacgt cgaggacgtg cgcgcgtggc tgggggcgag
    10681 cgggccgcgg cggtcgaagg aggccgaatt cgatatcgat ctcggcaatc tcaccctgcc
    10741 ggtcaccatc ctcgccgaat ccgccggtgt ccgtttcgaa ccggcgggcc gccgcagcgt
    10801 ccaggtgtta cgcgcgctga gcctggagga ttgggaaccg tgcctgcagg cgacattccg
    10861 catcgcgctc gatcatctcg accgcgcccg ttggcatctc gatcgcgccg aggagttcag
    10921 cggcgaccgg gaactggcgc gacgtgtcat cgaatgggcc gacgagatga tcgaatccgt
    10981 gcgccgcaag ggacttgata tgacattgag cgaattgccc caggtggccc gatgatccgg
    11041 gccgtcgtct tcgatatcgg tgaatgcgtg gtcaataccg aacgcgaata tcgccggtgg
    11101 gcccaatggc tgggcgttcc ggcacacacc ttcgccgccg cggtcgggat ggcattggcc
    11161 cgggggttcg acgagtacca cgcgctgcgg ctggtcgctc ccggtatcga cccggccgcg
    11221 gcgcgggccc ggcgcgcggt cgaggacgag ctggagtatt tcaccgagga cgatctctac
    11281 cccgatgtgc ggccggtgct gaccgcgctg cgggcccgcg gcgtgtggac cggcatcgcc
    11341 ggcaaccaga ccctcgagac ccgcgacatc ctgcgatcgc tgcgcctgcc gtgcgatctc
    11401 gtcgccacct cggagcagtg gggggtggcg aagcccgatc cggcgttctt ccggcggctg
    11461 gtgcagcaca ccccgttcga gccgggcgag attctgtacg tgggtgatcg actcgacaac
    11521 gacgtgcgcc ccgcggccgc gatgggcctg cacaccgcgc tcgtgcgccg cgggccgtgg
    11581 agcctgctgc aatcgccggg cgcgggcgac gagcccaccc tgcggatcgg ggagctcacc
    11641 gagctcgtgg gcctgctcga ccggctcgat cgcgatccgc tgcgggtatg actcgcccat
    11701 attccggtac gcccgtaccg gcgtggcgcg gcgtgccgca cgcggcgggt tcggcatagt
    11761 gaagagcgtg aacgagccgg atccaccggg ccgacggcac cggctgccca cccgccgcgg
    11821 cgggtggcgc cgtgcgctcg gctgcgtggc gctgggctgc gtgctgaccg cgtgcggctc
    11881 gaccgtgccc ggccggccca ccgccgaccc gtcgacgccg aagaaccggc acatcggcac
    11941 ggcattggcg acgctgctgc cgaagcagga tcagttcccg tcgccctatg cggcggtggt
    12001 gccgcccgcc gagcaggccg cgcacatcgc gggcgacctg agcggaatcc cgccgggcgc
    12061 caccgtggat ccggccgact gcgcgccgcc gcagcggccg accgggcccg acacgtccgc
    12121 cgtggtggtc ggcaccgacg ccgccacgcg gaccaccctc accgtgctgc tgacccgcgt
    12181 cgacacgccg ctgtcgacgg tgcggcagca ggcgcggggc tgcggcaccg tgcacgtgcg
    12241 ccgcggcccg atcaccgata ccgtgctgac ccaacccgat ccggcgccac cggtgcgtgc
    12301 cgacgacacg ttcgcgctgc accgcacggt gaccggcccg gcgaccgggc cggggctgac
    12361 ccggtcgatg cgtacgctgc tggcgcaggt gggagacgtg cggatcgagg ccaccgccat
    12421 gtcctacggc gacgggccgt ccgatccggc ggggctggat caggtgttcg tcgcggcggt
    12481 ggaggacgtg cgcgcgggct gacggcgtcg cgcgagcggg cgatcgtatc agcctgtgcc
    12541 gacaggaatc tcgatccgtg caccccggcg cggtgtcgtt ccacatgccg ggcggttatc
    12601 cccaggaccg ccgaaagccc aggtcggtgc gcgggcgagg gcggcggtgg cgcgcacgct
    12661 gaggcccatg acagcttccg ccgatcgccc cgccgacaac gacgccgccc gcgtcaccga
    12721 ggacaccgct ccggggtact cgccgccgga ccttccccga tacgactgcg cccgagggga
    12781 atccacgccc gagccggact ggcggcaccc actgctgcgg gtggagcagc ccgcggaatt
    12841 catcgccgcg ataccggccc tgctgggctt cgtgccggag cgctccctgg tggtgtgcct
    12901 gctgcaggac acccccgagc ggcccggcgc ggtgttcctg ggcgcggtgg cgcgccacga
    12961 cctggacgtg tccggctgcg gcgcctgggt gcgggtggcc gggcaactcg ccgcgatctg
    13021 cgtgcaggag cgcgccgtcg gggtggtggt cctggtcgtc gacgatcggg cgagcgtcac
    13081 ccgggcgggc cgccccggcg cgcgggcgag ccgccaccgc gacctgatcc gggcgctcgg
    13141 cggcgcgctg cgggccgcgg atgtcaccct cgccgacgcc tgggcggcgc gcgagatcgc
    13201 caccggcgca ccgtggtgga gcctgaccga cccggaacgc accggcaccc aacaggatcc
    13261 gtcggcctcg ccggtcacgc tcgcgcacgt gctcgacggc cgcccgatcc gttcctcgcg
    13321 cgccgagctg ctggcgaccg tcgaggtgga ccgcgaactc cgcgacgcgg tggccgccga
    13381 actggagcag gccgagctca ccgcgcggcg gctgtaccgg cgggccgtga gccgcagcgc
    13441 gccgggcgaa taccgccgcg ccgcgctgga gatggtgctc tggcagatcg cggccgtcgg
    13501 ttccgccgcc ccgattccac cggacgcggt cgccgatgtg gccgtcgcgc tgcgggattc
    13561 gacggtccgc gacgcgctgt tcgcgctcgc cgtcggcgag cacgggcggg cggccgagga
    13621 actgtggacc cggctgtgcc gcgccctgga cggccccgac cgggccgagg ccgccacgct
    13681 gctcggctac agcgcctaca ttcgcggcga cgggccgctg gccggggtcg cgctcgaggc
    13741 ggcgctggag gccgacccca gccacggcat cgccgggctg ctggagacgg cgctgcgcac
    13801 cgggatgcat ccgcaggaga tgcgcaagct ggcccgcagc ggggcgctgg ccgcggccgg
    13861 actcggcgta gatctcgggg tcgacccggc cgggtggcag tcgtgacacc cggtgcggcc
    13921 caggcccgga cgcggtcagc gggcgctgtg cgcgcggtcg ccgagcgacc gcaggaaggc
    13981 ccaggcgtcg gccacgatct cgtcgagatc gttgtgccgc gggttccacc ccagctcggc
    14041 cacggcccgc tcgctggagg cgacgagcac cgccggatcc ccggcccggc gcggcgcgtt
    14101 caccgccgcg atcgaccgtc cggtgacccg ctcgcaggcc gaaatcacct ggcgcaccga
    14161 gaaaccggtg ccgctgccca gattgaagag gcgatgcgca cccggccgcg actgcgccag
    14221 cgccagcaga tgcgcctgcg ccagatcgcg aatgtggatg tagtcgcgga tcgcggtgcc
    14281 gtccgcggtc gggtagtcgg tgccgaacac cgagatcgac tcccggtggc ccagcgccgt
    14341 ctgcagcacc agcggaatga gatgcgtttc caccacccgg ttctcgccga gcccgccgta
    14401 ggcgcccgcg acgttgaagt agcgcaggct ggtggccgcc agcccgtgcg ccaccgcgta
    14461 ggaggtgatg gcgtggtcga tggccagctt cgacgcgccg tacggattcg tcgggcgggt
    14521 cggggcgtcc tcggtgatcg gcacctgctc gggctcgccg tacaccgcgg cggtcgagga
    14581 gaacaccagc cgcggagttc cggtgcggcg catggcctcc agcagggcca gggtcttgac
    14641 cacgttgccg taccagtact tctccggctg ctgcaccgac tcgccgacca gcgactgcgc
    14701 cgcgaaatgc aggacgccgt cgaaggattc ggattcgatc agctccacgc cgacggtggc
    14761 gatatcgccg tcgacgaact tcgcgccgtt cggcacgccc tcggcattac cggtggacag
    14821 atcgtcgacc acgacaacct cgtgcccgtc ctcgatcagc acctgtgcgc agacgccgcc
    14881 gacgtatccc gcgccgcccg tgaccagaag tttcatgtat cagaccagct tcacctgaac
    14941 cgcatgggcc atctcgtcgg acaattcgaa accctcgtgc ccgggcaccg agatgaccac
    15001 cgcgccgggc ttggtctcca ccgtcacgcg ggcatcgggc accacgcccg cctcgcgcag
    15061 ctggttgatg atctccgggc cggtctggat gtgctcggac aaccggcgca ccaccaccgc
    15121 cgacacctgg ccgctcggca ggtccgacag gcggatcagc ttctcctcgg cgcccgaggt
    15181 cgggatcacg cccaattcgt ccagtcccgg aatgggattg ccgtaggggg aggtggtggg
    15241 gtgattgagc acctcgacga gccggcgctc gacgtcctcg ctcatcacgt gctcccagcg
    15301 gcacgcctcg gcgtgcacgt tctgccagtc caggccgatg acgtcgacca gcaggcgctc
    15361 ggccagccgg tgcttgcgca tgaccgcgac ggccatggcg cggcccttct cggtcagctc
    15421 gaggtggcga tcgccggcga ccagcaacaa tccgtcgcgc tccatgcggg caaccgtctg
    15481 gctcaccgtc gggccgctct gctcgaggcg ctcggcgatg cgcgcgcgca ggggcacgac
    15541 gccttcctcc tcgaggtcgt agatcgtacg gagatacatc tccgtggtgt cgaccagatc
    15601 cttcacctgt taccccttcg tcggcacgaa ttctacccac gcccggatct cgctccgtgc
    15661 gtcagcatat tcggcttgtc ctgcggaaac ttcgaacgcg cggcgcgtct cgggggcgcc
    15721 cggccgcggc gcgcccgtac tgtcttgcat ttctactgca tgacaacgac aaattgggtg
    15781 cccagcttcc ccgtgttcgg ttccgatgca ggtagcgcgc ccggtggcgg aggtgcatta
    15841 gcgtgacagc catggcacgt cgaccctcca gcggcgccac ggtggtgtgg accgatcggt
    15901 ttctcgatta cacctggacc ccggagcatc ccatgaaacc ggcgcggctg cggctcacca
    15961 tggaattggc gcgcggcctc ggtctgctcg agggtgtcga gaccgaggcg cccggcccgg
    16021 cgggcgaggc cgacctgctg cgcattcaca cccccgccta tgtcgaggcc gtccggggtg
    16081 cggtcccgcc gccaccggga accgcgctgc cgctggcggc cccgttcggg ctgggcacga
    16141 cggacgatcc gatcttcccg cgcatgcacg aggcggcctc ggtcctggtc ggcggcaccc
    16201 tggccgcggc cgaggcgatc gcggccgggc ggacccggcg cgcggtgagc atcgcgggcg
    16261 gcatgcatca cgcgatgccc gagtccgccg ccggattctg cgtgtacaac gatgtggccg
    16321 tggcgatttc ctggctgctc gaccacggct tcgaccgcat cgcctacgtc gacgtcgacg
    16381 tgcaccacgg cgacggggtg cagcgcgcgt tctacggcga cccccgcgtg ctgaccgtct
    16441 ccctgcacca gcacccggcc accctgtggc ccaacaccgg ctggcccgag gagaccggcg
    16501 cgggcacggc cgagggcacc gcgctcaatc tcacgatgct gcccggtacc cgggatgccc
    16561 agtggctgcg cggttttcac gcgatcgtgc cgggcgcgct ggcggcgttc cggccgcagc
    16621 tgctcgtcag ccagtgcggg gtggacaccc accgcgagga cccgctggcc gatctggaac
    16681 tcagcgtcga cggccagcgc gcggcgttcc tcgcgatgcg cgaactcgcc gaccggtacg
    16741 ccgagggccg ctggctggcg gtgggcggcg gcgggtacgg cgtggtgcgg gtggtgccgc
    16801 gcgcctggac ccacctgctg gccgcggccc tggaccgcga gatcgacccc gccaccgcgg
    16861 ttccggccga ctgggccgag cgggcccgcg cctacgcgcc gtccgtcgag ccgccgggca
    16921 ccatgggcga cggtgtcgac ccggccttcg accgctggga cggcccgggc ggcacccgcg
    16981 agaccggcga cgagcgcacc gaccgcgcgc agcgcgccct cgacaccgcc gtattggcca
    17041 cgcgccgagc gactttcggg ctgctgggcc tggacccgga ggacccccgt gactgaaccc
    17101 gccgcggggc acgacagcac gccccaggac ccgcccccgc cgccgcagca ctgggtggcc
    17161 gacgtgctgg ccgccgacgg cggcgtggta cgggtgcggc cgatcgcccc cgccgacgcc
    17221 gaggcgctgc agcgcttcca cgccgggctg tccgaccgca cccgctacct gcgctacttc
    17281 gggccgtacc cgcggatgac gccgaaggat ctgtaccgca ccacccacgt cgactaccgc
    17341 gaccgggtcg gcctggtcgt cgagctgggc gcggtgatca tcgcggtcgg ccgctacgaa
    17401 ctgctgccgg accgggaggg cccgcgggcg gccgaggtgg cgttcgtggt cgccgacgag
    17461 catcagggtc gcggtctggg ctcgatcctg ctcgagcatc tggcgggcgc ggccgccgag
    17521 aacggcatcg agaccttcgt cgccgaggtg ctggcggaga acaacgcgat ggtgacggtg
    17581 ttccgcgacg ccggatacca ggtgcagcgc agccgcgacg gctcggtgct gcacctggaa
    17641 ttcgccatcg acccgaccga agccctgctg tcggtgcggg attcgcgcga gcgcgcctcg
    17701 gaggcgcgca gcgtcggcaa tctgctcgcg ccgcgctcgg tggcggtgat cggcgcgacc
    17761 ccctcgtcgg gccgggtcgg cggcgcggtg ctggccaatc tgctgtccgg ggtgttccag
    17821 gggccggtgt tcccggtcaa cccgaatcgc agttcggtgc gcggcgtgcg cgcctatccg
    17881 accgtgcgcg aggttcccga cgaggtggac ctggcggtgg tggcggtgcc cgcgggggag
    17941 atcaaatcgg tgctcgacga ctgtatggcc aagggcgtca agggcttggt ggtgctcacc
    18001 gcggggttct ccgagatcgg cccggccggg tacgccgccg aacgcgatct ggtggcggcg
    18061 gcgcgcgggc acggcatgcg ggtggtgggc ccgagcgcgc tcggtatcgc caataccgat
    18121 ccggcggtct cgatgaacgc cacgctggcc ccggtgctgc ccggccgcgg ccggatcgga
    18181 ttcttctgcc agtccgggcc gctgggtgcg gcgatcctcg gtgaggccgc cgcccgcaag
    18241 ctcggactgt cgaccttcgt ctcggccggt aaccgtgccg acgtgtcggg caacgacatg
    18301 ctgcagtact gggacaccga ccccgacacc gacgtggtgc tgctgtatct ggagaccttc
    18361 ggcaatccgc gcaagttctc ccgcatcgcg cggcgggtcg cgcgcgggaa gccgatcgtg
    18421 gcggtgagca gcgggcgcaa tgccacgcac accgccgggg cgctggaccc gagccatccg
    18481 ctggaccggt cgctcgagcg cgacctgttc gcgcaggcgg gcatcgtgca ggtggacacc
    18541 atctccgaat tgttcgactg cgcaatgctg ttggcgtacc agccgctgcc gcccggcccg
    18601 cggctggcgg tgatcggcaa cagcgccgcg ctgggctggt tggcggtgga cgcggcccgc
    18661 ggcgaggggc tgaccgcggg cgcgccgacc gatctcggcc cgcaggccga gcccgccgac
    18721 tatctgacgg ccgttgcggc ggcgatggat tcgtcggacg tcgacgcggt gatcgtgatc
    18781 ttcgccccgc cggtgccgac ctcggtgacc gcctacgccg aggcgatccg cgcgggtgcg
    18841 ggcgcgggcg gcaaaccggt gctgaccacc ttcgtcgccg atctgggcat gccgaacctg
    18901 ctggccaccc gcggcatcgg cggcagcctc gagcgcggct cgatcccgtc ctatcccgat
    18961 ccggagcggg cggcgcgcgc cctggctcgg gtgcgccgct acgccgactg gcgcacccgc
    19021 ccggtgtcgc cggtgcgccg ccccgccgac gtggacaccg agcgggcgcg aaatctggtg
    19081 ggggagtgga tgcgtcgcga accggacggc ggctggctgg ccgatctgga ggcggtgcag
    19141 ctgctggact gctacggcat ccgggtggtc gagttccggg aggtgcgcga cccggaggcg
    19201 gcggaggcgg ccgccgagga actgggctat ccggtcgcgg ccaaggccac cggcgagctg
    19261 tggcgcaacc ggcccgacct caccggggtg cggctagatc tgtggcggcc ctcggcggtg
    19321 cggcgggcct acaccgatct ggccgaggtc tccggcaacg aggtggtgca cattcagaag
    19381 atggccacca agggcgtcgg ctgcgtgctg cgggtgcagg acgatccgtc gttcggttcg
    19441 gtgatcagct tcgggctgtc gggcaccatc atcgatctgc tgggcgaccg ggtgtatcgg
    19501 gcgctgccgc tgaccgagga cgaatcggcc gaactgatcg acgccccgcg cgccgcgccg
    19561 ctgctggatg gcaaggccgg ggtcgcgggc cgcaccatcg gcgagccggt ggacaagcgg
    19621 gcgctgtcgg agttggcccg gcgcatctcg gcgctgtgcg acgacctgcc ggagatccgg
    19681 gagctggcgg tggagccggc gctggcctcg gcgcggggcg cggcgatcct gtacgcgcgg
    19741 gtgcgcatcg ggcccgaacc cagccgcttc gacatcgggc cgcgacgact ggcctgacca
    19801 ccggcgaacg gcgttccggt acccgccccg ctgcgaggcg accggcggtg cacaatactg
    19861 gcaggcatgc gggaagatca gatcgaagca gcgaccgcgc cgctccggga cgacatccgg
    19921 ttcctcggcg cgatcctcgg agacaccatc catgaccacg agggcgcgga ggtgttcgat
    19981 ctcatcgaac gcgtccgcgt cgaggccttc cgggtgcgcc ggtcggaggt ggaacgcagc
    20041 gcggtggcgg agatgctgcg cgataccgac attcacgtcg cgatccccct gatccgggcg
    20101 ttcagccact tcctgctgct ggccaacctg tgtgaggacc tgcagcgcga ccggcggcgt
    20161 gcggtgcacg tggccgcggg cgagccgccg caggactcca gcctcgccgc cacctaccgc
    20221 aaactcgacg ccgccgggac cgacggcgcc acggtcgccg aacagctcgc cgacgcgctg
    20281 gtctcgccgg tcatcaccgc ccaccccacc gagacccgcc gccgcaccgt cttcgacgtg
    20341 caggcccgca tcaccgagct gatgcgcacc cgccagcgct acaccccggc cgaacccgaa
    20401 tacgccgaga tcgacaccca gctgcgccgc caggtgctgg cgctgtggcg ggccgcgctg
    20461 attcgcctgg cgcgcctgcg gattcaggac gagatcgagg tcggcctgcg ctactacgac
    20521 atgtcgctgc tggaggtgat cccgcgcatc aacaccgagg tgcgcgacgc gctgcgcgcc
    20581 cgctggccgc agtacgagct gctggagcgg cccatcctgc ggccgggctc gtggatcggc
    20641 ggcgaccgcg acggcaaccc gaacgtcacc ggcgaggtgg tgcaccgcgc cacccaccgc
    20701 gcgggtgcgg tcgccttcgc gcactacctg aaagagcttg tcggactgga gaagtcgctg
    20761 tcgcagtcgg cgcggctggt gcggatcacc ccggagctgg cgcggctggc cgacgccggg
    20821 cacgacgact ccccgcagcg cgccgacgaa ccgtaccgcc gggcggtgcg cggcatccgc
    20881 gcccggctca ccgcctcggc gcggcgggcg ctgggcgagg tgcccggcga cgcgggcgtg
    20941 gataccggtg cgcgcccgta cgattcgccg caggaactgc tggacgatct ggccgtcgtg
    21001 gacgcctcga tgcgcgcctc gggcgacggt ctgct
//
