LOCUS       NZ_KV411304            22630 bp    DNA     linear   CON 12-FEB-2024
DEFINITION  Nocardia terpenica strain IFM 0406 scaffold2, whole genome shotgun
            sequence.
ACCESSION   NZ_KV411304
VERSION     NZ_KV411304.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardia terpenica
  ORGANISM  Nocardia terpenica
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 4638951)
  AUTHORS   Buchmann,A., Eitel,M., Koch,P., Schwarz,P.N., Stegmann,E.,
            Wohlleben,W., Wolanski,M., Krawiec,M., Zakrzewska-Czerwinska,J.,
            Mendez,C., Botas,A., Moris,F., Cortes,J. and Gross,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-APR-2016) Pharmaceutical Biology, University of
            Tuebingen, Auf der Morgenstelle 8, Tuebingen 72076, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 30-JUL-2014
            Assembly Method                   :: CLC NGS Cell v. 7.0.4
            Genome Coverage                   :: 118.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/12/2024 01:56:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,832
            CDSs (total)                      :: 8,760
            Genes (coding)                    :: 8,562
            CDSs (with protein)               :: 8,562
            Genes (RNA)                       :: 72
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 40 of 198
            Pseudo Genes (incomplete)         :: 174 of 198
            Pseudo Genes (internal stop)      :: 9 of 198
            Pseudo Genes (multiple problems)  :: 23 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:51:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 135704
            Orig. end                         :: 158334
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KV411304.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22630
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="3"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22630
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22630
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12630](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12630
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            23..514
                     /gene="crcB"
                     /locus_tag="AWN90_RS21610"
                     /old_locus_tag="AWN90_21650"
     CDS             23..514
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:1903425 - fluoride transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:1903424 - fluoride transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crcB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019926003.1"
                     /locus_tag="AWN90_RS21610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21650"
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="WP_067586078.1"
                     /transl_table=11
                     /translation="MPEIRLAESGDPDVDLRFAEQCRELFRDHGAVLAVIAVGGGLGAI
                     ARYGIAQLLPTRPGHFPWGTFITNVAGCFAIGVLMVLITEVWSAHRLIRPFLGVGFLGG
                     FTTFSTYAVDTRNLLQPGTTATAFAYAAGTLLCAMLAVLTGVTLTRITVRRRETREDRR
                     "
     gene            511..852
                     /locus_tag="AWN90_RS21615"
                     /old_locus_tag="AWN90_21655"
     CDS             511..852
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018160226.1"
                     /locus_tag="AWN90_RS21615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21655"
                     /product="DUF190 domain-containing protein"
                     /protein_id="WP_067586082.1"
                     /transl_table=11
                     /translation="MKLTGYATRLQIFVGEDDIWHHRPVYHEIVRRAREAGLAGATVLR
                     GCEGYGGHSVIHTTRLLDLTEDLPAVIVIVDTDDKIRAFLPELDDLIGDGTVLLDEVEV
                     IRYQAKTPS"
     gene            849..1211
                     /gene="crcB"
                     /locus_tag="AWN90_RS21620"
                     /old_locus_tag="AWN90_21660"
     CDS             849..1211
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:1903425 - fluoride transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:1903424 - fluoride transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crcB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007534876.1"
                     /locus_tag="AWN90_RS21620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21660"
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="WP_067586087.1"
                     /transl_table=11
                     /translation="MTVALVFLGAMIGAPARYLADRVVQTRHDSIFPWGTFTVNLIGCL
                     ILGGLTGAAASSPILAVLGTGFCGALTTYSTFSYETLRLLEQRAHFYATVYVAVSVIAG
                     LGAALLGYTAMHATLT"
     gene            complement(1268..1738)
                     /locus_tag="AWN90_RS21625"
                     /old_locus_tag="AWN90_21665"
     CDS             complement(1268..1738)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018159810.1"
                     /locus_tag="AWN90_RS21625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21665"
                     /product="nitroreductase/quinone reductase family protein"
                     /protein_id="WP_082871217.1"
                     /transl_table=11
                     /translation="MASPRAAGQARTMASQRVVNRIVGVLLRVPGVSIAVGRRLVLLHI
                     VGRKSGKHYDIPVAYTRYDGSLLIGTSFAWGRNLRTGDRIGVVLQGKRRTADVRAISDE
                     AGVVEYYGIIVRDNHAFAKFNNIGFTATGDPDPDHLHQAYAAGARAFLLTLR"
     gene            complement(1768..2238)
                     /locus_tag="AWN90_RS21630"
                     /old_locus_tag="AWN90_21670"
     CDS             complement(1768..2238)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014982385.1"
                     /locus_tag="AWN90_RS21630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21670"
                     /product="nitroreductase family deazaflavin-dependent
                     oxidoreductase"
                     /protein_id="WP_067586094.1"
                     /transl_table=11
                     /translation="MTLADTAAGLGARALRTRWLVRAPIRLYRAGLGVAFGTRLLMLEH
                     RGRRTGARRYVVLEVVDHPAPDEYVIVSGFGDRAQWYRNIRADPRVRVWTGRRRALPAT
                     ATPLTDRQSATALDHYIHQHPRAWKNLRATIEHATGTSVDTLPMVRLHIARP"
     gene            complement(2276..4630)
                     /locus_tag="AWN90_RS21635"
                     /old_locus_tag="AWN90_21675"
     CDS             complement(2276..4630)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003934306.1"
                     /locus_tag="AWN90_RS21635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21675"
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_067586097.1"
                     /transl_table=11
                     /translation="MRTTRNRMLGRKLRRDLRRRPAQAVAIAVTVMLGVLLFVASYDSF
                     RNLSASYEQTYARLHFADLTATGTDPAALADAVRTAPGVARVAVRTQADVPMTIDAAKL
                     LGRITGLPADPGAGVDEISLTAGRMPDPAHPGDVVIEQHTADTFGLRVGARLRIHDGTA
                     WQDVTVTGIARSPEYLWPARSRQDVLDDPHTFAIVFAPQPQALRLAGRPGPDQALVALD
                     PTASGSDRDHVATLLRAAGATDVTGRADQPSNAALHEDLNGFSEIAVGFPLLFLLAAGI
                     AEYVLITRLVRAERPVIGTLLAMGARRGTLIRHYTTYGLAVAAVGAVAGVASGAVVTSA
                     VTAAYTHAVGIPDTVVAHRIATAAVGFALGLTAGALAGLVPALAAARTAPARAMRGDGA
                     RPLRPGPLARISARWTALPVVARMALRSLTRDRRRTAATMTGTVLALVLILASVGMVTS
                     MYHVVNIQFGQVDREDATVIAAPGTGGPAAQVRQVPGVAAVEPERVAPITVRANGRTYA
                     TQLTGLPPDTRMHGFRITSGGPGLPADGVLAGSALSGRLGVHVGDILTVTPAFGTPQRV
                     RLAGLVDEPLGTLLYATDSTATRLAPTAADGYLLRFDTGTDHDAVRAAVTGLPGVLAYT
                     DTHALDTEFHRFLALFWIFIGVMLLLGAVLAFTVIYVTMTVNLAERTTELATLRAAGVP
                     IRRLTAAVAAENLTATALAAPLGLAAGIGVAWMFLRSFTSDMFTLHLWLGIAAPTLAVL
                     AVLAAAAVSQLPALRVVRRIDIARVVRERAL"
     misc_feature    complement(4613..4631)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 24.76"
                     /tool="antismash"
     gene            complement(4636..5373)
                     /locus_tag="AWN90_RS21640"
                     /old_locus_tag="AWN90_21680"
     CDS             complement(4636..5373)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011738962.1"
                     /locus_tag="AWN90_RS21640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21680"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_067586100.1"
                     /transl_table=11
                     /translation="MTDRRHPVTTRRGGFRLRGVGKTYGVGEAAVHALDDVALDVSPGE
                     LVAVLGPSGSGKTTLLNIIGGIESADTGTIVVAGQDISRGRPAALGEFRRARIGFVFQF
                     FNLIPTLTARENVEVIIELTGRGDRTRVPDLLAAVGLTDRAGHFPAQLSGGQQQRVSIA
                     RALATDPDLLLADEPTGALDVATGRGVLELLQRTARAGRGVVMVTHNEVAAAIADRVVR
                     MRDGRIIADQPNPAPVDAADVRW"
     gene            complement(5370..5954)
                     /locus_tag="AWN90_RS21645"
                     /old_locus_tag="AWN90_21685"
     CDS             complement(5370..5954)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020731848.1"
                     /locus_tag="AWN90_RS21645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21685"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_067595502.1"
                     /transl_table=11
                     /translation="MVTSAEQGRETRARLMDAAVELIAERGWGAVTTRMVAERAELRPG
                     LVHYHFNSVNDLLIDASLRMVRALASDVLGEGLDRSGPAGLDRLLAAIAAYTVAEADTR
                     VFSEMLLAATRYERLQEGLGVVLREFRAAVAAWLRSSGSVPDPEATAVVLVAALDGLIL
                     HRLIDPRLGELGVDGPLRRLTGMSGIGGDRR"
     gene            complement(6086..6574)
                     /locus_tag="AWN90_RS21650"
                     /old_locus_tag="AWN90_21690"
     CDS             complement(6086..6574)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014982387.1"
                     /locus_tag="AWN90_RS21650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21690"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_067595504.1"
                     /transl_table=11
                     /translation="MARRDTVAEESVDEITDALLTASRLLVALSARSIAHVDDSITIPQ
                     FRTLVILSTRGPSKIATLAAILNVQPSTATRMVDRLVAAGLLDRKPNPESRRELIIEPT
                     ARGRKIVTAVTAQRRKEIAAVVEHMPAADRAGLVRALTAFSAAGGEPQADTDIESYQL"
     misc_feature    complement(6644..6659)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.75"
                     /tool="antismash"
     gene            6758..9004
                     /locus_tag="AWN90_RS21655"
                     /old_locus_tag="AWN90_21695"
     CDS             6758..9004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014983549.1"
                     /locus_tag="AWN90_RS21655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21695"
                     /product="hypothetical protein"
                     /protein_id="WP_067586105.1"
                     /transl_table=11
                     /translation="MPRTDAVRWGLITIVGVVAGYAAVLAANPRHFYTDDTESQYGPMW
                     VMLGRQLRDGHFPALVPYEWMSGNYSMEEAGLYNPPQLLVDLIAPSVDNLALYVTVVKL
                     VFSIIAALGVFRVCRAYGARASWAAVAGVAFPLSGWFLFFDESSWATSLTGTAWMLHAW
                     ASAVRYVRGRGDGATRRGGPIPVFVFLYLAISVQYVFPAVESALMIVAVAVGEVIYRRL
                     WGPSLRLLAVAACAGLAGLETYLPGILSSPVTWRGNERILNEQFLTVGWSESLNASLPS
                     TVPAFTGWWGYVQPIPMVYIAWFVIPLLAFIDWRAVKNAAREHSGLVLFVVMFLMWTAG
                     PGRVGPLRWPARVLPMLAVGLLVLVCVLLSRYGSFAEWRRRGIAAAVLIGLLFVRTFSA
                     APHLVLRHLMWTAIVAALVAALVWLARTRGTAIACVLAIVAMFPIAYDQVRAQSPTPMS
                     YHFPERRSQTAAAFPHFAGVTLQLADRALIPPADQRLDRAWGSLAFGNYAKNIGLEYVN
                     AYTPIGYAAFSALLCMGWDGSTCPDAYRRAFATEPSTGRTIVDLMKVDRVVLQRAQYPD
                     AGHHPAPPGWRWVDYPGHDSYIRVLERADGPISARNGLIADTRGVTATSLERTSVTSHV
                     HVTSATGGQVVFARLAWPGYRVTLDGRDIGFHTIAKTFLAVDIPPGTHNADLTLTWRPP
                     GWKIGIATALAGLLGLSLLQWRYRRGRREDDDPVTDPAAADPRPEADDLATVPA"
     misc_feature    6791..6805
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    7928..7930
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    8348..8350
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            9001..>9114
                     /locus_tag="AWN90_RS48230"
                     /pseudo=""
     CDS             9001..>9114
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005184335.1"
                     /locus_tag="AWN90_RS48230"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="MerR family DNA-binding transcriptional
                     regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTCTTCEKVRALHHYDRIGLLVPSSRTSGGHRCYTQAD"
     misc_feature    complement(9684..9697)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.11"
                     /tool="antismash"
     misc_feature    9727..9741
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.96"
                     /tool="antismash"
     gene            9763..9888
                     /locus_tag="AWN90_RS49025"
     CDS             9763..9888
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS49025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_269456502.1"
                     /transl_table=11
                     /translation="MTTMQKMSYIEPEVIRLGTVEEHTAALTHGHPDLLGHGDIL"
     misc_feature    complement(9902..9916)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.21"
                     /tool="antismash"
     gene            10001..11725
                     /locus_tag="AWN90_RS21660"
                     /old_locus_tag="AWN90_21700"
     CDS             10001..11725
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="AWN90_RS21660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21700"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_082871219.1"
                     /sec_met_domain="Asn_synthase (E-value: 8.1e-10, bitscore:
                     36.9, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGPAPLTVDQLGCAGRTTLPGNGSPIDYDCVPYTAFPERTAPASP
                     AYLRQWLRPGSDRTAGFTRPLERAYLALGGTLASTPDAALADGIIAALRNGRYAELAGL
                     PGDLTGCLVTSERVFLFRSLFTRNTVFYKQSGNTLEWSSDPADLVPDPLDRLDRGTIWR
                     ICRGDAILAYPELRFLRPGTVAVFDGATVDIVEYDRIKPKPLPRGSTPQDYADRAWELL
                     LAAARPYARSGRVGLLLSGGMDSSAVAAALVACGAEVTAYHLDTDDSLADESGYAAAVC
                     QHLSIPLVPIATDIGPGHLSADWRFPHPYNHKGYRWLEQTVQRVRQDGLALLTWGRDGD
                     LLFGPVLRYGVHDVLFGRLSVAEKRLMLRGLLSSRWTLPNLIKSIGRSHSLVTDNAPVG
                     ENAQHTDFLVPMSGLPFTFPDPEFLPEEQTTDLALAWPHGVQFCSPMADRELYELMTGM
                     PTAYRCIPYGGRIIGKPVLRLLLKDRVPPLIWRRHGRLWLDSPHETFCLKHRPLFAELL
                     GADSMLARMNIVDPQRLAAVLADPLSIRRNTETLICTAMTELFLHGLESRSSHPVRS"
     misc_feature    11429..11431
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11732..12007
                     /locus_tag="AWN90_RS21665"
                     /old_locus_tag="AWN90_21705"
     CDS             11732..12007
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.4"
                     /locus_tag="AWN90_RS21665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21705"
                     /product="PqqD family peptide modification chaperone"
                     /protein_id="WP_067586113.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.8e-13,
                     bitscore: 48.4, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2e-09, bitscore: 35.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLLQLGNDAILDTTDGVGIILDTREGVYFQLNPTATLMVQTAMT
                     CETEAEALRQLEQRIDASPEQLRAGLTKLIGQLTEHRLLARTDAAR"
     aSDomain        11741..11989
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AWN90_RS21665_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.10E-15"
                     /identifier="RREFam002.1"
                     /label="AWN90_RS21665"
                     /locus_tag="AWN90_RS21665"
                     /protein_end="86"
                     /protein_start="3"
                     /score="48.4"
                     /tool="antismash"
                     /translation="LQLGNDAILDTTDGVGIILDTREGVYFQLNPTATLMVQTAMTCET
                     EAEALRQLEQRIDASPEQLRAGLTKLIGQLTEHRLLAR"
     gene            12004..12630
                     /locus_tag="AWN90_RS21670"
                     /old_locus_tag="AWN90_21710"
     CDS             12004..12630
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024862.4"
                     /locus_tag="AWN90_RS21670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21710"
                     /product="lasso peptide biosynthesis protein"
                     /protein_id="WP_067586116.1"
                     /sec_met_domain="PF13471 (E-value: 3.3e-09, bitscore: 34.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLAPQLESMLSDIDGVPPPPRLPHRLRGYALRRSWTALRLLRT
                     EGWAPAYRYLADLTPGPDRLLPGRLEPPVAIRLARREVLFSQSVLRAVHPNGLCLPRSL
                     ALATYLAAIGLPAQVIVARERICTNPRYGFHSWTELHGEVLNDNQDVTLGFTVLQRVSA
                     SAVGVDSNPPRRNSRIPGRRGMPVRWGDRGSGGGGAVPGGVSEQA"
     gene            complement(12583..14541)
                     /locus_tag="AWN90_RS21675"
                     /old_locus_tag="AWN90_21715"
     CDS             complement(12583..14541)
                     /GO_function="GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1037: heavy metal
                     translocating P-type ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019046199.1"
                     /locus_tag="AWN90_RS21675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21715"
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="WP_067586120.1"
                     /transl_table=11
                     /translation="MVASTVSPARSASAPVPVRRTRLFALPEMRWAGLALGLFALGLIA
                     QLAGAPHWTWWALYLACYAAGGWEPGLAGLRALRDKTLDVDLLMVVAAIGAAAIGQITD
                     GALLIVIFATSGALEALATARTEDSVRGLLDLAPETATRVTADADEEVVAAAELEVGDV
                     LVVRPGERIPADATVIGGGSEVDQATITGEPLPVDKTPGEEVFAGTLNGTGVLRLRVDR
                     RTADSVVARIASLVEQASRTKARTQLFIEKVEQRYSLAMVAVTLAVFVVPLLAGETLQR
                     ALLRAMTFMIVASPCAVVLATMPPLLAAIANAGRHGVLAKSAIVMEQLGTISRIAFDKT
                     GTLTRGTPELTEIHSVEPRFDSDELLRLAAAAEHPSEHPLAAAIVKAARAHHLPLPAVD
                     EFTAHPGRGVSALVGERFIGVGSAAALLAEHPDTGAAAQTVARLQNQGYTAVVVTCEGH
                     PIGVLAISDRTRPEAADAVAAAERVTGHTPVLLTGDNRATAARLAAQVGITDVRAGLLP
                     DAKADTVHEMQADGTRIAMVGDGLNDAPALAIAQIGIAMGGAGSDLTLHTADAVIVRDD
                     LTTVPTMIALSRRARRVVVANLAIAATFISVLVIWDLVGTLPLPLGVAGHEGSTILVGL
                     NGLRLLRHTAWHRATTT"
     gene            14638..15000
                     /locus_tag="AWN90_RS21680"
                     /old_locus_tag="AWN90_21720"
     CDS             14638..15000
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_218261.1"
                     /locus_tag="AWN90_RS21680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21720"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_067586123.1"
                     /transl_table=11
                     /translation="MGHGVEGRDRPVARLDADAAAHVANTLQALATPSRLLILTELRQG
                     PLPVTELAEAVGMEQSAVSHQLRLLRNLGLVVGTRTGRSIIYSLYDTHVAQLLDEAVYH
                     SEHLRLGLSDKPETAG"
     gene            complement(15018..15590)
                     /locus_tag="AWN90_RS21685"
                     /old_locus_tag="AWN90_21725"
     CDS             complement(15018..15590)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF028506.4"
                     /locus_tag="AWN90_RS21685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21725"
                     /product="DUF5134 domain-containing protein"
                     /protein_id="WP_171983309.1"
                     /transl_table=11
                     /translation="MNHEMGLMSTMLPVWIRVAWSIALAVVAVLHLWHAAALRGQPRWW
                     HGVHTAMAVGMAAMYAADPMKQAGLDRAMFTVFAVVAVGLVVVTAGVGRREGAANPLWA
                     LTVVGAAAMAYMSAVMLWPQAIGPVVSWVVIAYLCVDAIGWAFGVWDRLAVLRRESIGL
                     AGHDSVDVRISLAVMAASMAYMLAAMM"
     gene            complement(16063..17199)
                     /locus_tag="AWN90_RS21690"
                     /old_locus_tag="AWN90_21730"
     CDS             complement(16063..17199)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1104: putative esterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012958.4"
                     /locus_tag="AWN90_RS21690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21730"
                     /product="alpha/beta hydrolase-fold protein"
                     /protein_id="WP_067586126.1"
                     /transl_table=11
                     /translation="MSLTGDGLFYALVAIAVAAMLITLIGWNVVRGPRPLRWLTRLIMI
                     GACQFTAVAVVAVWINDANGLYTSWNDLLGRPDDQAEAVSTAPEPVRFRDTGGGVLGID
                     YRGPESRLRGRVLIWTPPQYRRDIHGDYRFPVIMLLHGVPGSPQAWIKGGRATTLLAAM
                     MRTGRLPPAILVMPRVDPGVNTDCTDVPRGPRTATWLAHDIPRLVASHFRALDRPSGWA
                     VVGDSTGGYCAAKLPLQFPAVFGTGLAFAPDDFRGDPAVIPSRALRLANDPVRLARTGA
                     PVSLLVVTGGHDPYSSPANARALYTAATPPTRVAAPLIVSGGGHNWGTWQAMYPRAFAW
                     LGAHLSLPRKGSVPTTPQATSVPRVQAAAPAAMPPRSR"
     gene            complement(17222..17377)
                     /locus_tag="AWN90_RS45910"
     CDS             complement(17222..17377)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS45910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_156674367.1"
                     /transl_table=11
                     /translation="MRLLRSGRRWAPIGCLAIGSAPILSSACTPDRTLGGQQVSTTMTL
                     DTVTRR"
     misc_feature    complement(17498..17514)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.07"
                     /tool="antismash"
     misc_feature    17606..17619
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.03"
                     /tool="antismash"
     misc_feature    17614..17626
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.83"
                     /tool="antismash"
     gene            17699..19450
                     /locus_tag="AWN90_RS21695"
                     /old_locus_tag="AWN90_21735"
     CDS             17699..19450
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009078284.1"
                     /locus_tag="AWN90_RS21695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21735"
                     /product="chloride channel protein"
                     /protein_id="WP_231951587.1"
                     /transl_table=11
                     /translation="MPARIPVWEWVRESHGGLIGLALMIGAGAGLGAIVFRWLILTFTR
                     ILSGRADYSAAGHAAHPWLPALGPWFVVLAPVVAGLIYGPLVTRFAPEARGHGVPEVMY
                     AVAARGGRIPPQVSVVKALASALCIGGGGSVGREGPIVQIGSAWGSSLGRVVRVPENRL
                     RILVACGAAGGIAATFNAPIAGPFFAMELILRDFTAESFGAVVLSSVTASVIGRAAFGN
                     RPFLDLPAFALKSGWEYLGFAILGLVIGAVGVAFTHILYRIEDACDWVWRGPEWLRPAV
                     GGLLLGGLLLVLPQMYGVGYPVLGHAIDGGYALWMLLALMIGKMIATSLTIGIGGSGGV
                     FAPSLFIGAMGGTAFGIAVHHLFPAATAAPGMYGLVGMGAAFAGATRAAITAVIILFEL
                     TGEYTIILPLMLAIVAATSISRVLSRETIYTLKLTRRGVDLDAAHHGPAHRLDRLTVGT
                     VMELMPEPIPADTPIDTASRAIWLSANGVLPIIGSDQRYHGCLTARAVAEALADPDATD
                     HTIADLAVIPPKITETSTLTHALDALTHTDDTGLPVLDRDGHTLVGWLTHRTILTALQQ
                     TTPAPPP"
     misc_feature    18527..18529
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(19583..20587)
                     /locus_tag="AWN90_RS21700"
                     /old_locus_tag="AWN90_21740"
     CDS             complement(19583..20587)
                     /NRPS_PKS="Domain: PKS_ER (14-330). E-value: 2.1e-35.
                     Score: 114.3. Matches aSDomain:
                     nrpspksdomains_AWN90_RS21700_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007296163.1"
                     /locus_tag="AWN90_RS21700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21740"
                     /product="NADPH:quinone reductase"
                     /protein_id="WP_067586132.1"
                     /sec_met_domain="ADH_N (E-value: 6.2e-09, bitscore: 33.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2e-20, bitscore:
                     71.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVVYSETGPSSVLRLVQRPDPVPGWGEVVVRIVRAGVNPTDWK
                     FRAGLADISGEIAPGQDGAGVVEAVGPGVDHVRVGERVWLLLAQQGRAYGTATELTVQP
                     ANRVIPLPDRASFDLGAALGVPFITAHRLLTSGTVTRLAPGALTGQTVLVAGGAGAVGN
                     AAIQLARWAGATVITTVSSTTKATLARAAGADHVVNYRESDPAAEILAIAPDGVDLIAE
                     VAPAPNATLDLAVTRIHGTIAVYASNGGDDLVLPLRAAYSKNLRFQFTILYTLDQTLLR
                     AAVDDITAALTDNALRVGVDAGLPLHHYDLAQTAAAHDAVEQGAVGKVLLDLD"
     aSDomain        complement(19598..20545)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AWN90_RS21700_PKS_ER.1"
                     /evalue="2.10E-35"
                     /label="AWN90_RS21700_PKS_ER.1"
                     /locus_tag="AWN90_RS21700"
                     /protein_end="330"
                     /protein_start="14"
                     /score="114.3"
                     /tool="antismash"
                     /translation="LRLVQRPDPVPGWGEVVVRIVRAGVNPTDWKFRAGLADISGEIAP
                     GQDGAGVVEAVGPGVDHVRVGERVWLLLAQQGRAYGTATELTVQPANRVIPLPDRASFD
                     LGAALGVPFITAHRLLTSGTVTRLAPGALTGQTVLVAGGAGAVGNAAIQLARWAGATVI
                     TTVSSTTKATLARAAGADHVVNYRESDPAAEILAIAPDGVDLIAEVAPAPNATLDLAVT
                     RIHGTIAVYASNGGDDLVLPLRAAYSKNLRFQFTILYTLDQTLLRAAVDDITAALTDNA
                     LRVGVDAGLPLHHYDLAQTAAAHDAVEQGAVGKVL"
     CDS_motif       complement(20081..20143)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AWN90_RS21700_0003"
                     /evalue="2.00E-06"
                     /label="PKSI-ER_m5"
                     /locus_tag="AWN90_RS21700"
                     /protein_end="169"
                     /protein_start="148"
                     /score="20.3"
                     /tool="antismash"
                     /translation="GQTVLVAGGAGAVGNAAIQLA"
     CDS_motif       complement(20162..20182)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AWN90_RS21700_0002"
                     /evalue="2.80E+00"
                     /label="PKSI-ER_m2"
                     /locus_tag="AWN90_RS21700"
                     /protein_end="142"
                     /protein_start="135"
                     /score="1.7"
                     /tool="antismash"
                     /translation="SGTVTRL"
     CDS_motif       complement(20375..20410)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AWN90_RS21700_0001"
                     /evalue="1.30E-02"
                     /label="PKSI-ER_m2"
                     /locus_tag="AWN90_RS21700"
                     /protein_end="71"
                     /protein_start="59"
                     /score="8.7"
                     /tool="antismash"
                     /translation="GQDGAGVVEAVG"
     misc_feature    complement(20543..20545)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(20668..20928)
                     /locus_tag="AWN90_RS21705"
                     /old_locus_tag="AWN90_21745"
     CDS             complement(20668..20928)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019926520.1"
                     /locus_tag="AWN90_RS21705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21745"
                     /product="hypothetical protein"
                     /protein_id="WP_067595508.1"
                     /transl_table=11
                     /translation="MMMWYAHDLSGWGYGLMAVGMMLFWAMLFLGLITAIRYTDSTRRA
                     ESSDDAPQHNPTPQQILALRYARGEIDDNEYARRSRTLEAG"
     gene            21117..22037
                     /locus_tag="AWN90_RS21710"
                     /old_locus_tag="AWN90_21750"
     CDS             21117..22037
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016208 - AMP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014984468.1"
                     /locus_tag="AWN90_RS21710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_21750"
                     /product="universal stress protein"
                     /protein_id="WP_067586134.1"
                     /transl_table=11
                     /translation="MVEQLDDMHHLASAAVVVGVDGSDASERALDWAVALAAQRRRAVR
                     IVHGLGLDRISQVCGRYDVWVPPVLDAARVRAETLVERCARRARDAAPEVRVDTEVSSE
                     APAALLRRLSGSAYLTVLGAAGTNGLRAHLGTTLLAVTAHGFGSIAVVRTNPDTDAVRE
                     DGPVVVGVDGSAVSEAALGAAFEEASQRGAELVAVHVWNDANFGEFAGDPYLLFLVPDI
                     EVNEHAVLAERLAGWQEKYPDVTVTRSVAMSSPAGILRKWSESAQLVVVGSRGRGGFQG
                     LLLGSTSNSLVQHANCPIMVVHPAK"
ORIGIN
        1 gccgttcgag taggagcctg tcgtgcccga aatccgtctc gccgaatccg gcgatcccga
       61 cgtcgatctg cgctttgccg agcagtgccg cgaattgttc cgcgaccacg gcgccgtgct
      121 ggccgtcatc gcggtcggcg gcgggctcgg tgccatcgcc cgctatggca tcgcccaact
      181 cctgcccacc cggcccgggc acttcccgtg gggcacgttc atcacgaacg tggcaggctg
      241 tttcgccatc ggtgtcctca tggtgctcat caccgaggtg tggtccgcgc accggctgat
      301 ccggccgttc ctcggcgtcg gctttctcgg cggcttcacc accttctcca cctacgccgt
      361 cgacacccgc aacctcctcc aacccggtac caccgcaacc gctttcgcct acgccgccgg
      421 taccctgctg tgcgccatgc tcgccgtcct caccggtgtc accctgaccc gaatcaccgt
      481 gcggcggcgc gagactcgag aggaccggcg atgaagctca ccggatacgc cactcgcttg
      541 cagatcttcg tcggcgagga cgacatctgg caccacaggc ccgtctacca cgagatcgtg
      601 cgccgcgccc gcgaagccgg gctcgccgga gccaccgtcc tgcgcggctg tgaaggctac
      661 ggcggccact cggtcatcca caccacccgg ctgctcgacc tgaccgagga cctgcccgcc
      721 gtcatcgtca tcgtcgacac cgacgacaag atccgcgcct tcctccccga actcgacgac
      781 ctcatcggcg acggcaccgt cctgctcgac gaggtcgaag tcatccgcta ccaggccaag
      841 accccgtcat gaccgtcgca ctcgtcttcc tcggagccat gatcggcgct cccgcccgct
      901 atctggccga tcgtgtcgtg cagacccgtc acgacagcat cttcccctgg ggcacattca
      961 cggtgaacct gatcggctgc ctgatcctcg gcggcctcac cggcgccgcc gcctccagcc
     1021 cgatcctcgc cgtactcggc accggcttct gcggggcact gaccacctac agcaccttca
     1081 gctacgaaac cctgcgccta ctcgaacaac gcgcccactt ctacgccacc gtctacgtcg
     1141 cggtcagcgt catcgccggt ctgggagccg cactgctcgg ctacaccgcc atgcacgcca
     1201 ctctcacctg atggcaggca cggcatgcag tacgagcccg ccctatcagg acgacgagcc
     1261 gggagattca gcgcagggtg agcaggaacg ccctggcccc tgccgcgtaa gcctggtgta
     1321 gatggtcggg atcagggtcg ccggttgcag tgaagccgat gttgttgaac ttggcgaagg
     1381 cgtggttgtc tcggacgatt atcccgtagt actcgaccac gcccgcctcg tcgctgatgg
     1441 cccgcacgtc ggcggtacgg cgtttgcctt gcagcacaac gccgattcga tcgccggtgc
     1501 gtaggttgcg gccccaggcg aacgatgtac cgatcagcag cgacccgtcg tagcgggtgt
     1561 aggcgaccgg tatgtcgtag tgtttgcccg acttgcggcc cacgatgtgc agcaacacca
     1621 gtcgtctccc cacggcgatg gagacacccg gcacgcgaag cagcacgccc acgatcctgt
     1681 tcactacacg ttgcgaggcc atggtccgag cctgacccgc cgctcgtggg gaagccatat
     1741 ctccacggta gtccctccgg gcgccgttca gggccgggcg atgtgcaggc ggaccatggg
     1801 cagggtgtcg acggatgtgc cggtggcgtg ttcgatggtg gcgcgcaggt ttttccacgc
     1861 ccgggggtgc tggtggatgt agtggtcgag ggcggtggcc gattgccggt cggtcagcgg
     1921 tgtcgcggtg gcgggcaggg cgcggcggcg gccggtccag actcggacgc gggggtcggc
     1981 ccggatgttg cggtaccact gggcgcggtc gccgaatccg gagacgatga cgtactcgtc
     2041 gggtgcggga tggtcgacga cctcgaggac cacgtagcgg cgggctccgg tgcgtcggcc
     2101 gcggtgttcg agcatgagca accgggtgcc gaacgcgacg ccgagaccgg cgcggtagag
     2161 gcggatggga gcgcggacga gccagcgggt ccgcagggcg cgagccccga gtccggcggc
     2221 ggtgtcggcg agtgtcatcg gtgagtcctt tccgaagtcg ttgtggtgga gcgggtcaga
     2281 gggcgcgttc gcggacgacg cgggcgatgt cgatgcgccg cacgacgcgc agcgcgggca
     2341 gttgtgacac ggccgcggcg gccagcacgg caaggacggc aagggtgggt gctgcgatgc
     2401 cgagccacag gtgcagggtg aacatgtcac tggtgaacga ccgcaggaac atccacgcga
     2461 caccgattcc ggcggccagc ccgaggggtg cggcaagcgc tgtggcggtg aggttttcgg
     2521 ccgccacggc ggcggtgagg cggcggatgg gcacaccggc cgcgcgcagg gtggccagct
     2581 cggtggtgcg ttcggccagg ttcacggtca tggtgacgta gatgacggtg aatgccagga
     2641 ccgcccccag gaggagcatg acgccgatga atatccagaa cagggcgagg aatcggtgga
     2701 attcggtgtc cagggcgtgg gtgtcggtgt aggcgagcac gccgggcagg ccggtcaccg
     2761 cggcgcggac ggcgtcgtgg tcggtgccgg tgtcgaagcg gagcaggtag ccgtccgcgg
     2821 cggtcggtgc cagccgcgtg gcggtggagt cggtggcgta gagcagggtg ccgagtggct
     2881 cgtccacgag cccggccagc cggacccgct gcggtgtgcc gaatgccggt gtaacagtga
     2941 ggatgtcgcc gacatgtacg ccgagccgtc cggacagggc ggacccggcg agcacgccgt
     3001 cggcgggcag gccgggtccg ccgctggtaa tgcggaatcc gtgcatgcgg gtgtcgggtg
     3061 gcagtccggt cagctgggtc gcataggttc ttccgttggc ccgcaccgtg atcggggcga
     3121 ctcgttcggg ctcgacagcc gccactcccg gcacctgccg cacctgcgcg gccgggccgc
     3181 cggtgcccgg ggcggcgatc acggtggcgt cttcccggtc gacctgcccg aattggatgt
     3241 tcacgacgtg atacatgctg gtgaccatgc cgaccgaggc caggatcagg accagtgcca
     3301 gcacggtgcc ggtcatcgtg gccgcggtgc ggcggcggtc ccgggtcagt gaccgcagcg
     3361 ccatgcgggc gacaacgggg agggcggtcc agcgcgcgga gattcgcgcc agcgggcccg
     3421 ggcgcagcgg gcgggcgccg tcgccgcgca tcgcccgagc gggcgcggtg cgcgccgcgg
     3481 ccagcgccgg taccagacct gccagtgccc cggcggtcag tccgagcgcg aatccgactg
     3541 ccgcggtggc gatccggtgc gcgaccacgg tgtcggggat gccgacggcg tgtgtgtagg
     3601 ccgcggtcac cgccgaggtg acgaccgcgc ccgacgcgac accggccacc gcgccgacgg
     3661 cggcgacggc caggccgtag gtggtgtagt gccggatcag ggtgccgcgg cgtgccccca
     3721 tcgccagcag cgtgccgatc acgggccgct ctgctcggac gaggcgggtg atcagcacgt
     3781 attcggcgat cccggcggcg agcaggaaca gcagcggaaa gccgacggcg atttcggaga
     3841 acccgttgag atcttcgtgc agggcggcat tcgacggctg gtcggcgcgg ccggtcacgt
     3901 cggtggcgcc cgccgcccgc agcagggtgg cgacatgatc gcggtcggat ccggaggccg
     3961 tcgggtccag cgcgaccaga gcctggtcgg gtcctggtcg gcccgccagg cgcagagcct
     4021 gtggctgtgg ggcgaacacg atggcgaacg tgtgcgggtc gtcgagcacg tcctggcggc
     4081 tgcgggcggg ccacaggtat tccggggagc gggcgatccc ggtgacggtc acgtcctgcc
     4141 aggcggtgcc gtcgtggatc cgcagtcgcg cgccgacgcg caggccgaag gtatcggcgg
     4201 tgtgctgttc gatcaccaca tcgcccggat gcgcgggatc gggcattcgc cctgcggtga
     4261 gcgatatctc gtccacaccg gcgccggggt cggcgggcag gccggtgatg cggccgagga
     4321 gtttggcggc gtcgatggtc atcggcacat cggcctgagt ccgtaccgcc acccgggcca
     4381 ccccgggcgc ggtgcgcacg gcgtcggcga gcgcggccgg atcggtgccg gtggcggtca
     4441 ggtcggcgaa atgcagtcgc gcataggtct gttcgtagga ggccgacagg ttacggaacg
     4501 agtcgtagct ggccacgaac aacaacaccc ccagcatcac ggtcaccgcg atggccaccg
     4561 cctgcgcagg ccggcggcgc aggtcgcggc gcagcttgcg gcccagcatc cgattccggg
     4621 tcgttcgcat gtccctcacc accggacgtc ggccgcatcg accggtgcgg gattgggctg
     4681 gtcggcgatg atgcggccgt cccgcatccg gaccacccga tcggcgatcg cggcggcgac
     4741 ctcgttgtgg gtgaccatca ccaccccgcg cccggcacga gcggtgcgct gcaacagctc
     4801 gagtacgccg cgcccggtcg cgacgtcgag ggcgccggtc ggttcatcgg ccaacagcag
     4861 gtccggatcg gtggccagcg cacgggcgat cgacacccgc tgctgctgcc cgcccgacag
     4921 ctgcgccggg aaatggcctg ccctgtcggt caagccgacc gcggccagca gatcgggcac
     4981 ccgggtccgg tcgccgcgcc cggtgagctc gatgatcacc tcgacgttct cccgggcggt
     5041 gagcgtggga atcagattga agaactggaa cacgaaaccg atacgggcgc gccggaattc
     5101 acccagcgct gcgggccggc cgcgcgagat gtcctgcccg gcaaccacga tcgttccggt
     5161 atcggcggat tcgatacccc cgatgatgtt gagcagcgtc gtcttgccgg acccgctcgg
     5221 ccccagcaca gccaccaatt cgcccggtga cacgtcgagg gcgacgtcgt cgagggcgtg
     5281 gacggcggcc tcgccgacgc cgtaggtctt gccgacgccg cgcagccgga acccaccacg
     5341 gcgcgtggtc acgggatgtc gtcgatctgt catcgccggt caccgccgat gccggacatc
     5401 ccggtcaggc ggcgcagcgg accgtcgaca ccgagttcac ccagccgagg atcgatcagc
     5461 cgatgcagga tgagaccatc cagcgcggcc accaggacca ccgccgtcgc ctcgggatcg
     5521 ggcaccgaac ccgagctccg cagccacgcc gcgaccgccg cccggaactc ccgcagcacc
     5581 acaccgagcc cttcctgtag acgctcgtat cgcgttgccg ccaacagcat ctcgctgaac
     5641 acccgagtat cggcctccgc gaccgtataa gcggcgatcg cggcgagcaa ccggtccagc
     5701 cccgcgggcc cggaccggtc cagcccctcg ccgagcacgt cagacgcgag cgcgcggacc
     5761 attcgcagcg aggcatcgat cagcagatcg ttgaccgagt tgaagtggta atgcaccagt
     5821 cccggccgca gctcggcgcg ctcggccacc atccgggtgg tcaccgcgcc ccagccccgc
     5881 tcggcgatca actccaccgc cgcgtccatc agccgggccc gtgtctcacg gccctgttca
     5941 gcggatgtca ccaccacgac ccccttcccg cccacgcacc ttggtcattc acattgggcg
     6001 catgcccaat ctagcagagc agtgcagtct gcaacagttg ctatgggcgt ggaatcggtg
     6061 aaccgggccg gtcgtgagcc tggtgtcaga gttggtagct ctcgatatcg gtgtcggcct
     6121 gcggttctcc gcccgcggcg ctgaaggcgg tcagtgcccg gaccagcccg gcccggtcgg
     6181 cggcgggcat gtgttcgacc accgcggcga tctccttgcg gcgttgcgcg gtgacggcgg
     6241 tgacgatctt gcggccacgc gcggtcggct cgatgatcag ctctcgccgc gactccggat
     6301 tcggtttgcg gtcgaggaga ccggcggcga ccaggcggtc caccatgcgg gtcgcggtcg
     6361 agggctgcac attcaggatc gcggcgagcg tggcgatctt ggacgggccc cgggtcgaca
     6421 ggatcaccag ggtgcggaac tgcgggatgg tgatcgagtc gtcgacatgg gcgatggacc
     6481 gcgccgacaa tgccaccagc aaccgcgagg cggtcagcag ggcatcggtg atctcgtcca
     6541 cggattcctc ggccaccgta tcccttcgcg ccatgacttc cccttcgtcg ccgtttccat
     6601 cgaacacctc catcctgccg cttccgcccg aatcggtagg cattcacaca gacattcgtc
     6661 cgaccggtcc ggccgacacc aatcatgcat aaagaaactg ttgcatactg cccccgtccg
     6721 gtagtgtctc cggctcgtgg gcgaacgcgc aggtctcatg ccgcgaacgg atgcggtgcg
     6781 gtgggggttg atcacgattg tcggtgtggt cgcggggtac gcggcggtgc tggcggccaa
     6841 cccgcgccac ttctacaccg atgacaccga atcccagtac ggacccatgt gggtcatgct
     6901 cggtcggcaa ctacgcgacg gccatttccc cgccctggtg ccctatgaat ggatgtcggg
     6961 caattactcg atggaagagg ccgggctcta caacccgccg cagctgctgg tcgatctcat
     7021 cgccccgtcg gtggacaatc tggcgctgta tgtcaccgtc gtgaaactgg tcttctcgat
     7081 catcgccgcg ctcggggtgt tccgggtctg ccgggcctac ggggcgcggg cgtcgtgggc
     7141 ggcggtggcc ggggtggcgt tcccgctgtc gggctggttc ctgttcttcg acgaatccag
     7201 ttgggcgaca tcgctgaccg ggaccgcgtg gatgctgcac gcgtgggcgt cggcggtgcg
     7261 gtatgtgcgc ggtcgcggcg acggtgctac gcgacgcggc gggccgattc cggtgttcgt
     7321 gttcctgtat ctggcgatct cggtccaata cgtgttcccc gcagtggaat ccgcgctcat
     7381 gatcgtcgcg gtcgcggtcg gcgaggtgat ctaccgccgc ctgtggggcc cgtcgctgcg
     7441 gctgctggcg gtggccgcgt gtgccggtct ggcgggcctg gaaacctatc tgccgggcat
     7501 cctgtcctcg ccggtcacct ggcgtggcaa cgagcgcatc ctcaacgagc aattcctcac
     7561 cgtgggctgg tcggagtcgc tcaatgccag cctgcccagc accgtgcccg cgttcaccgg
     7621 ctggtgggga tacgtgcagc cgataccgat ggtctacatc gcctggttcg tgattcccct
     7681 gctcgcgttc atcgactggc gggcggtcaa gaacgcggcc cgcgagcact ccgggctcgt
     7741 gttgttcgtc gtgatgtttc tgatgtggac ggcggggccg ggccgggtcg ggccgttgcg
     7801 ctggcccgca cgggtattgc cgatgctcgc ggtgggcctg ctggtgctgg tgtgcgtgct
     7861 gctcagccgc tacggcagtt tcgccgagtg gcggcggcgc ggcatcgcgg cggccgtcct
     7921 gatcgggtta ctgttcgtcc ggaccttcag cgccgcaccg catctggtgc tccggcatct
     7981 gatgtggacc gccatcgtcg cggcgctggt cgcggcgctc gtatggctgg cgcgcactcg
     8041 cggcaccgcg atcgcctgcg tgctcgccat cgtggccatg tttcccatcg cctacgacca
     8101 ggtacgcgcc caatcaccca ccccgatgtc ctaccacttc cccgagcggc gctcccagac
     8161 cgccgcggca ttcccgcatt tcgcgggtgt caccctgcaa ctggccgacc gcgccctgat
     8221 cccgcccgcc gatcaacgcc tcgatcgtgc ctggggctca ctggctttcg gcaactacgc
     8281 caagaacatc gggctggaat acgtgaacgc ctacacccct atcggctacg ccgccttcag
     8341 cgccctgtta tgcatgggct gggacggcag cacctgcccc gatgcctatc gccgcgcgtt
     8401 cgcgaccgaa ccgtccaccg gccgaacgat tgtcgacctg atgaaggtgg atcgcgttgt
     8461 gctgcaacgc gcccagtacc ccgacgccgg tcaccaccct gctccaccgg gctggaggtg
     8521 ggtcgactac cccggccacg acagctacat ccgggtgctc gaacgcgccg acggcccgat
     8581 ctcggcccgc aacggcctga tcgccgacac ccgcggcgtc accgccacct ccctcgagcg
     8641 caccagcgtc accagccatg tccacgtcac ctccgccacc ggcggccagg tcgtcttcgc
     8701 ccgcctggcc tggcccggct accgcgtcac cctcgacggc cgcgacatcg gcttccacac
     8761 catcgccaaa acctttctcg ccgtcgacat cccacccggc acccacaacg cggacctcac
     8821 cctcacctgg cggccccccg gctggaagat cggcatcgcc accgcactgg ccggactcct
     8881 cggcctgagc ctgctgcagt ggcggtaccg ccgcggccgc cgcgaggacg acgacccggt
     8941 caccgacccg gccgccgccg acccacgacc ggaagcggat gacttggcca ccgtgcccgc
     9001 ctgacctgca caacgtgcga aaaggtgcgg gcgttgcacc attacgaccg gatcgggctg
     9061 ttggtgccgt cgtcgcggac atcgggcgga catcggtgct atacccaggc cgaccattac
     9121 gatgagtcga ccattgactc cagcggaatt cgctcggctg acgcggcaac gcgaaggata
     9181 cgcacggcag tcgagtgcgg aagagcttgc agcactggcg aaacggcgtg ctgtcctccc
     9241 gcggtcccct cgcccaccag atccgccgca tggaggcgag tgccgaggag gacggccgcg
     9301 gcgtgcgagc ccacctcgcc gaggggggta tacgccgact tcgggctgcc gccccgggga
     9361 cgttaccgcc gtccggggcg actgcatcga tctgccgaca ccggaacaac tcgcggtgat
     9421 cggcgaggtc ttcgaactta tcgataaaga aatcgacaac cgctcgtagc acgaattgga
     9481 acccgttcgg aaacaaatgc ggcgcagtct aattggaccg gcctaccggc gcgaagtttg
     9541 accgcattta gggggtcgac gcaaagggct tccgaaggct acggttggaa cctgacagtt
     9601 gatcgacttg cttccgagat cccttgtagc acagcggagt acgttcgcga ccgaccagca
     9661 tgaatcacat ttcaccagac cggtaggaat gattctacat tgcctgccgt cttattttca
     9721 cgctcccgaa attcgtatcc acgagaatga aggagaaagg aggtgacaac aatgcagaag
     9781 atgtcctaca tcgagcccga ggtgattcgc ctggggaccg tcgaggagca tactgccgcg
     9841 ctgacgcacg gtcatcctga cctgctcggc catggcgaca tcctgtaacc gcacgcagtg
     9901 atggccaatc ccatcccttc ccctccctcg gcgcgctgtc cgcgtcgggg gaggggatca
     9961 cggcgccgaa gcgcctgccg aacgagaggt ttcgtgcatc atgggtcccg ctccgctcac
    10021 cgtggaccag ctcggctgtg ctggccgaac aactctgccc ggcaacggat ctcctatcga
    10081 ttacgactgt gtgccctata cggccttccc cgaacggacc gccccggcca gcccggcgta
    10141 cctgcggcaa tggctgcgcc cgggctcgga tcggacggcc gggttcacgc gcccgctcga
    10201 gcgcgcctac ctcgcactgg gcggcacact cgccagcacc ccggacgccg cgctcgccga
    10261 cgggatcatc gcggcgctgc ggaacggacg gtacgcggag ttggccgggt tgccggggga
    10321 tctgaccggc tgcctggtca catcggaacg ggttttcctg ttccgcagcc tgttcacccg
    10381 caacaccgtg ttctacaagc agtccggcaa caccctggaa tggtccagcg atcccgccga
    10441 tctggtgccc gatccgctcg accgactgga tcgcggcacc atctggcgga tctgccgcgg
    10501 cgacgccatc ctggcctatc cggaattgcg gtttctccgt ccggggaccg tggcggtctt
    10561 cgacggcgcg acggtcgaca tcgtcgagta cgaccggatc aagccgaagc cgctgccgcg
    10621 aggcagcacg ccgcaggact acgcggaccg ggcctgggag ttgctgctgg cggcggcccg
    10681 gccctatgcg cgcagcggtc gcgtcggact gctgctcagc ggcggcatgg attcctcggc
    10741 cgtggccgcg gcactggtgg cctgcggtgc cgaggtgacc gcctaccacc tcgataccga
    10801 tgattcgctg gccgacgagt ccggctatgc cgcggcggtg tgccagcatc tgtcgattcc
    10861 cttggtgccg atagcgaccg atatcggtcc cgggcatctg agcgcggact ggcggtttcc
    10921 ccatccctac aaccacaagg ggtaccgctg gctggaacag accgtgcagc gggtccggca
    10981 ggacggactg gcgctactga cctggggtcg agacggtgat ctgctgttcg gtccggtcct
    11041 gcgctacggc gtgcacgatg tgctgttcgg ccgcctgagc gtggcggaga aacgcttgat
    11101 gctgcggggc ctgctcagtt cccgctggac gctgccaaat ttgatcaaga gcatcggccg
    11161 ctcgcattcc ctggtgaccg acaacgcccc ggtcggcgag aacgcgcagc acaccgattt
    11221 cctggtgccg atgtccggtc tgccgttcac atttcccgat ccggagttcc tgcccgagga
    11281 acagaccacc gatctcgcgc tcgcgtggcc gcacggggtg caattctgct ccccgatggc
    11341 cgaccgggaa ctgtacgagc tgatgaccgg catgccgacg gcctaccgct gcattcccta
    11401 cggcggccgc atcatcggca aaccggtatt acggttgctg ctgaaagacc gtgtgccacc
    11461 gctgatctgg cgtcggcacg gtcggctgtg gctggactcg ccgcacgaaa ccttctgtct
    11521 gaagcaccgg ccgttgttcg ccgaactcct cggcgccgac tcgatgctgg cgcggatgaa
    11581 catcgtcgac ccgcagcggt tggcggccgt tctggccgat ccgctgtcga tccgccgcaa
    11641 taccgagacc ctgatctgca cggccatgac cgagcttttt ctccacggcc tggaaagccg
    11701 gtcgtcgcac ccggtgagga gctgatcacc aatgtcactg ctgcaactcg gtaacgatgc
    11761 cattctcgac accaccgacg gcgtcggcat catcctggac acccgcgaag gcgtctactt
    11821 tcaactgaac cccaccgcca cgctcatggt gcagacggcg atgacctgcg aaacggaggc
    11881 cgaagccctc cggcagctcg aacagcgcat cgacgcgagc ccggagcagt tgcgcgccgg
    11941 actcaccaag ctgatcggtc agctcaccga acatcgcctg ctcgcgcgaa cggacgccgc
    12001 ccgatgaccg acctggcacc tcaactcgag tccatgctct ccgatatcga tggcgtacca
    12061 cccccgcccc gcctgcccca tcggctccgc ggttatgcac tgcggcgaag ctggacggcg
    12121 ctgcgcctgc tccgcaccga gggctgggct ccggcatacc gctacctcgc agacctgacc
    12181 cccggaccgg accgactgct acccggccgt ctggaaccgc cggtagcgat ccggctcgcc
    12241 cgccgcgagg tcctgttcag tcaatcggtc ttgcgcgcgg ttcaccccaa cggcctgtgt
    12301 ctgccccgct cgctggcact ggccacctac ctcgcggcca tcggcctacc cgcccaggtc
    12361 atcgtggccc gcgaacgcat ctgcaccaac ccgcgctacg gcttccactc ctggaccgaa
    12421 ctgcacggcg aggtcctcaa cgacaaccag gacgtcacgc tgggcttcac tgtcctgcaa
    12481 cgagtctccg cctcggcggt gggcgtggat tcgaaccctc cgcgacggaa ctcccgcatc
    12541 cccggccgga ggggtatgcc ggtgcgttgg ggcgaccggg gttcaggtgg tggtggcgcg
    12601 gtgccaggcg gtgtgtctga gcaggcgtag cccgttgagg ccgacgagga tggtcgagcc
    12661 ttcgtgtccg gccacgccca gcggtagcgg cagggtgccc acgaggtccc agatgaccag
    12721 cacgctgatg aaggtggcgg cgatggcgag gttggcgacg accacccggc gggctcggcg
    12781 cgacagcgcg atcatggtgg ggacggtggt gaggtcgtcg cggacgatga ccgcgtcggc
    12841 ggtgtgcagg gtgaggtcgg atccggcccc gcccatcgcg atgcctatct gggcgatcgc
    12901 gagggcgggt gcgtcgttga ggccgtcgcc gaccatcgcg atccgggtgc cgtcggcttg
    12961 catctcgtgg acggtgtcgg ccttggcatc ggggagtagt cccgcgcgga cgtcggtgat
    13021 accgacctgc gcggcgagcc gtgccgcggt ggcccggttg tcgccggtca gcaacacggg
    13081 ggtgtggccg gtcacgcgct cggctgcggc gaccgcgtcg gcggcttcgg ggcgggtccg
    13141 gtcactgatg gccaggacgc cgatggggtg gccttcgcag gtcacgacca ccgccgtgta
    13201 gccctggttc tgcaaccggg cgacggtctg cgcggccgca ccggtgtcgg ggtgctcggc
    13261 gagcagcgca gcggcagacc cgacaccgat gaacctctcg ccgaccagcg cggagacacc
    13321 gcgcccgggg tgggcggtga attcgtcgac ggcgggcagc gggagatggt gtgcgcgtgc
    13381 ggctttcacg atcgcggcgg cgagggggtg ctcgctggga tgctcggcgg cggctgccag
    13441 gcgaagcagt tcatcggagt cgaatctcgg ttccacgctg tggatttcgg tgagttcggg
    13501 tgtgcctcgg gtcagggtgc cggtcttgtc gaacgcgata cgggagatgg tgcccagctg
    13561 ttccatcacg atcgcggatt tggcgagcac gccgtggcga ccggcgttgg cgatcgcggc
    13621 cagcagcggc ggcatggtcg ccagcaccac cgcgcacggg gaggcgacga tcatgaacgt
    13681 catcgcccgc aacaaggccc gctgtagcgt ctcaccggcg agcagcggca ccacgaacac
    13741 cgcgagcgtg accgccacca tggcgagcga gtagcgctgc tcgaccttct cgatgaacaa
    13801 ctgggtgcgg gccttggtgc ggctggcctg ctcgaccagc gacgcgatgc gcgccaccac
    13861 cgagtcggcg gtgcggcgat ccacgcgcag acgcaagacg ccggtgccgt tgagggttcc
    13921 ggcgaacacc tcctcgcccg gggtcttgtc caccggcagc ggttcgccgg tgatcgtggc
    13981 ctgatcgacc tcgctgcccc cgccgatcac cgtggcatcg gcgggaatcc gctcaccggg
    14041 ccgcaccacc agcacatcac cgacctccag ctcggccgcc gccacgacct cctcgtcggc
    14101 gtcggcggtg acgcgggtcg cggtctcggg tgccaggtcc agcagtccac gcaccgagtc
    14161 ctcggtgcgc gcggtggcca gggcttccag cgccccggag gtggcgaaga tgacgatcag
    14221 cagtgcgccg tcggtgatct ggccgatcgc cgccgcaccg atcgccgcga cgaccatcag
    14281 cagatccacg tccagggtct tgtcccgcaa cgcccgcaac cccgccagac ccggctccca
    14341 cccacccgcg gcgtagcagg ccagatacaa cgcccaccac gtccagtgcg gcgcgcccgc
    14401 cagctgagcg atcaggccca gcgcgaacaa acccagagcc aaccccgccc accgcatctc
    14461 cggcagcgcg aacaacctcg tgcggcgcac cggcaccgga gccgatgccg agcgggccgg
    14521 actgacggtc gatgcgacca cgagccacct ccacagcgaa agcaatcaac tcggcccacg
    14581 ataacagaac agatgaacac atcttcatgt ctcatgttca cggtaggctg ctccggtatg
    14641 ggacacggag tcgagggccg cgaccggccg gtagcacgcc tggatgccga cgccgccgcc
    14701 cacgtggcca acaccctgca ggcgctggcc acgccgagcc ggttgctgat cctgaccgaa
    14761 ctccgccagg ggccgctgcc ggtgaccgag ctcgccgagg cggtcggcat ggagcagtcc
    14821 gcggtctctc atcagttgcg cctgctgcgc aacctcggcc tggtcgtcgg cacccgcacc
    14881 gggcgcagca tcatctacag cctctacgac acccacgtcg cccaactgct cgacgaagcc
    14941 gtctaccaca gcgaacacct gcgcctgggc ctgtccgaca agccggaaac cgctggctga
    15001 caccagcatt cactcttcta catcatcgcg gccagcatgt acgccatgct cgcggccatg
    15061 acggccaggc tgatccggac atcgaccgaa tcgtggcctg ccagcccgat ggattcgcgc
    15121 cgcagcaccg ccaggcgatc ccagacgccg aacgcccagc cgatcgcgtc gacacacaag
    15181 tacgcgatca cgacccacga caccacaggg ccgatcgcct gcggccacag catgaccgcc
    15241 gacatgtacg ccatcgcggc ggcaccgaca acggtcaacg cccacaacgg attcgccgcg
    15301 ccctcccgac ggcccacccc ggccgtcacc acgacgagcc cgaccgccac cacagcgaag
    15361 accgtgaaca tcgcccgatc gaggccggcc tgtttcatcg gatcggcggc atacatcgcg
    15421 gccatgccca ccgccatcgc ggtatgcacc ccgtgccacc accgcggctg cccccgcaac
    15481 gctgcggcgt gccacaaatg cagcaccgcg acgacagcca acgcgatcga ccacgccact
    15541 cgaatccaca ccggcagcat cgtggacatc aagcccatct cgtggttcat gggcatgaca
    15601 cttcgcatat tcggtccact cacgccgtac acgggtcaat agtcggctcc gaccgccacc
    15661 gagttcccga tcgcgattcg tccgtcgaca aaactagcac atagcaacta ttgcagagtg
    15721 ccactatact tgtggcgcta tgcacgcttc ggcgtaacga gagccgacta cgaggaactg
    15781 agctccatgg cactggacat cctggctttc tctttggcca caatgcttct gaccacgatc
    15841 gtggccatgc tggcgatcgg ccttaccgac ctgctggagc caccgacctc cacctggtgc
    15901 cgacaatgcc tgcggtggac gatcgacaac caccatgaat cggaacgggt atgcccacgc
    15961 tgccgcgggg ctcaccggaa agcgcgaaca tcggtccggg cgcacaggac tactccggcc
    16021 ggacacaccg cgacgctccg gcccggacga ccggctccac actcatcgtg accgcggtgg
    16081 catggcagcc ggtgcggcgg cctggacgcg ggggacgctc gtggcctgcg gagtcgttgg
    16141 gacggaacct ttccggggca ggctgagatg ggcgccgagc caggcgaatg ccctcgggta
    16201 catcgcttgc caggtgcccc agttgtgccc gccgccggag acgatgagcg gtgcggccac
    16261 gcgggtgggt ggcgtcgcgg cggtgtacag cgctcgcgcg ttggcgggac tgctgtaggg
    16321 gtcgtgcccg ccggtgacca cgagcaggga taccggtgcg ccggtgcgcg ccaggcgcac
    16381 ggggtcgttg gccaggcgca gggccctgct gggaatcacc gccgggtcgc cacggaagtc
    16441 gtcgggcgcg aacgccagtc cggtgccgaa gacggccgga aactgcagcg gaagtttggc
    16501 ggcgcagtag cccccggtcg agtcgcccac cacggcccat ccggacggcc ggtcgagggc
    16561 acggaagtgg ctggcgacga ggcgggggat gtcgtgggcg agccaggtgg cggtccgcgg
    16621 gccgcggggg acatcggtgc agtcggtgtt gacgcccggg tcgacgcgcg gcatgacgag
    16681 aatggccggt ggcagccgcc cggtgcgcat catggcggcg agcagcgtgg tggcgcggcc
    16741 ccctttgatc catgcctgcg ggctgccggg cactccgtgc agcagcatga tcaccggaaa
    16801 ccggtagtcg ccgtggatgt ctcggcgata ctgcggcggt gtccagatca ggacacgacc
    16861 gcgcagcctc gattcgggtc cgcggtagtc gatgccgagg acgccaccgc cggtgtcgcg
    16921 aaaacgtacc ggctcgggtg cggtcgagac cgcttcggct tgatcgtccg gccgaccgag
    16981 cagatcattc cacgaggtgt acaggccgtt ggcgtcgttg atccacaccg cgaccacagc
    17041 gaccgcggtg aactgacagg cgccgatcat gatcaggcga gtcagccagc gcagcgggcg
    17101 tgggccgcgc acaacgttcc acccgatcag ggtgatgagc atcgccgcga ccgcgatggc
    17161 caccagcgca tagaacaggc cgtcaccggt caggctcatc gggtcgccgc ctcgtgttcg
    17221 gtcatcggcg ggtcacggta tcgagcgtca tcgtcgtgga gacctgctgg ccgcccagcg
    17281 tcctgtccgg cgtgcaggcc gaggacagga tcggagccga acctattgcc agacaaccga
    17341 tcggcgccca tcgccgaccg gaccgcagca gcctcatcgt gacctccgcc ggtatcgctc
    17401 gacgggccac cgcggccggg ccgggcaggc acggccgggc gcacggcaga acctgctcat
    17461 cgctgtcggt cgcaccgaac tgcccatcgc catccccatg cgagcagtat gcaacagttg
    17521 ttcactgcat gggtagcgag tggcgtgtgc gcggatcgcg cgggcagcgc cgagggggag
    17581 catcccccca cggattcaca cccactacaa ttattgcact ctgcaagttt ctgatgaggg
    17641 tgcgatgaca gcaacacgaa cacgaccggc ggaccgcgat cgacggtggt ccttaccggt
    17701 gccggcgcga atcccggtgt gggagtgggt acgagagagc cacggcgggc tgatcgggct
    17761 ggcgctgatg atcggcgcgg gagcgggcct gggggcgatc gtgttccgct ggctgatcct
    17821 gacattcacc cggatcctgt ccggccgtgc cgactactcg gccgccgggc atgccgccca
    17881 cccctggttg cctgcgctgg gaccgtggtt cgtggtgctg gccccggtcg tcgcgggcct
    17941 gatctacgga cccttggtca cccggttcgc gcccgaggcg cgtggtcacg gggtgcccga
    18001 ggtcatgtac gccgtcgccg cccgcggcgg ccggattcct ccgcaggtct ccgtcgtcaa
    18061 ggcgctcgcc tcggcgctgt gcatcggcgg cggcggatcg gtcggccggg agggaccgat
    18121 cgtgcagatc ggctcggcgt gggggtcgag cctgggccgc gtggtccgtg tgcccgagaa
    18181 ccggctgcgc atcctggtgg cctgcggtgc cgccggtggt atcgcggcca ccttcaacgc
    18241 tccgatcgcc gggccgttct tcgcgatgga gctgatcctg cgcgacttca ccgccgaatc
    18301 cttcggcgcg gtcgtcctgt ccagcgtgac cgccagcgtc atcggccgcg ccgcgttcgg
    18361 caaccgcccc ttcctggacc tgcccgcgtt cgcactgaaa tccgggtggg aatacctggg
    18421 cttcgcgatt ctgggcctcg tgatcggtgc cgtcggtgtc gcgttcaccc acatcctgta
    18481 ccggatcgag gatgcctgcg attgggtgtg gcgaggcccg gaatggttac gccccgctgt
    18541 cggcgggctg ctgctcggcg ggttgctgct ggtgctgccg cagatgtacg gcgtgggcta
    18601 cccggtactc ggccacgcca tcgacggcgg atacgcgctg tggatgttgc tggcgttgat
    18661 gatcggcaag atgatcgcca ccagtctcac catcggcatc ggcggctccg gcggggtgtt
    18721 cgcaccgtca ctgttcatcg gggcgatggg cggtaccgcc ttcggcatcg ccgtccacca
    18781 tctgttcccc gccgcgaccg ccgcacccgg tatgtacggg ctcgtcggca tgggcgcggc
    18841 cttcgcgggc gccacccgcg ccgcgatcac cgccgtcatc atcctgttcg agctcaccgg
    18901 cgaatacacc atcatcctgc cgctgatgct cgccatcgtc gcggcgacca gcatctcccg
    18961 cgtcctgtcc cgcgagacga tctacaccct caaactcacc cgccgcggcg tcgatctcga
    19021 tgcggcacac cacggtccgg cacaccgcct ggaccggctc accgtgggga cggtcatgga
    19081 actcatgccc gaaccgatcc ccgccgacac acccatcgac accgccagcc gcgcgatctg
    19141 gttgtccgcc aacggagttc tacccatcat cggctccgac cagcgctacc acggctgcct
    19201 caccgcccga gccgtcgccg aagccctcgc cgaccccgac gccaccgacc acaccatcgc
    19261 cgacctggcc gtcatacccc cgaaaatcac cgaaacctcc accctcacac acgctctcga
    19321 cgcactcacc cacaccgacg acaccggcct ccccgtcctc gaccgcgacg gccacaccct
    19381 cgtcggctgg ctcacccacc gcaccatcct caccgcccta caacagacca cacccgcacc
    19441 cccaccttga attgtggctc accggacgac tgggccgtcc ctttagtgtc catcggtttg
    19501 gattcgacac actatgtcgg ctgcggcgtg gtactgagca gcggcatcag caccacacca
    19561 gcagagtgca cgatggaatc gctcagtcaa ggtcgagcag gaccttgccg accgctccct
    19621 gttcgaccgc gtcgtgcgcg gcggcggtct gggccaggtc gtagtggtgt agcggaagac
    19681 cggcgtcaac gcctacccgg agggcattgt cggtgagtgc ggcggtgatg tcgtccacag
    19741 ccgctcgcaa cagcgtttgg tcgagggtgt agaggatggt gaactggaag cgcaggttct
    19801 tgctgtaggc cgcccgcagg ggcaacacca ggtcgtcgcc gccgttgctg gcgtagaccg
    19861 cgattgtgcc gtgaattctg gtcacggcca ggtcgagagt ggcgttgggc gccggtgcga
    19921 cctcggcgat gaggtcgacg ccatcgggtg cgatcgcgag gatttcggcc gccgggtcgc
    19981 tctctcggta attcaccaca tggtcggctc cggcggcgcg cgcgagcgtc gctttcgtgg
    20041 tggaactgac ggttgtgatg acggttgccc ccgcccagcg ggccagttga atcgcggcgt
    20101 tgccgacggc accggcgcca ccggcgacga gcacggtctg tcccgtcaag gcgcccggcg
    20161 ccagccgtgt caccgtgccg gaggtcagca gccgatgcgc ggtgatgaac ggcacgccca
    20221 gtgcggctcc aaggtcgaag gatgctcgat ccggtagagg tatcacccga ttcgccggtt
    20281 gcaccgtcag ttcggtagcg gtgccatacg cgcggccctg ctgagccagc agcagccaca
    20341 cccgctcacc gaccctgacg tgatcgacac caggcccgac tgcctcgacg acgcctgcgc
    20401 cgtcttggcc cggcgcgatc tcaccggaga tatcggccaa gcccgcacga aatttccagt
    20461 ccgtcggatt cacgcccgca cgcacgatgc ggaccaccac ctcaccccac cccgggacgg
    20521 ggtcgggtcg ctggacaagc cgtaagacag acgacgggcc ggtctcggag tagacgactg
    20581 cacgcataac ccgattcaac cagggcacac tcgagtatct tccaggaccg catcggtgaa
    20641 cgtgtcggcc aagacgcaca gggctggtca accggcctcc agcgtccgcg atcggcgcgc
    20701 gtactcgttg tcgtcgatct ctccgcgcgc gtaccggagg gccaggatct gctgtggtgt
    20761 cggattgtgt tgtggcgcat cgtcggagga ttcggcgcgc cgggtgctgt cggtgtagcg
    20821 gatggcggtg atcaggccga ggaacagcat tgcccagaac agcatcatgc cgaccgccat
    20881 cagcccgtac ccccatccgc tcaggtcgtg ggcataccac atcatcatca cgaacctccg
    20941 tcgcgggacc gtgggtggac actgccgatt gtgcaaccgg agaccggctt tcgcggcggc
    21001 ccaactgccc cggggacgag gactttaggc cgcatcgccc agggtgcgcg gattcctacg
    21061 gtgatggttg tccacccgga tagcgggcat cccacggccg agggaaaggg ttcgcgatgg
    21121 tcgagcaact cgatgacatg caccacttgg cgtcggcggc ggttgtggtc ggcgtggacg
    21181 gttccgacgc ctcggagcgg gcgctggact gggcggtcgc actcgccgcg caacgccgac
    21241 gcgcggtgcg gatcgtgcac ggcctgggtc tggatcggat atcgcaggtc tgcggtcgct
    21301 acgacgtgtg ggtgccgccg gtgctggacg ccgcgagagt tcgggcggag acgctggtgg
    21361 agcggtgcgc tcgccgggcg cgagacgccg cgccggaggt ccgggtcgac accgaggtgt
    21421 cgtcggaggc cccggccgcg ctgctgcggc ggctcagcgg ctcggcgtat ctgaccgtgc
    21481 tcggggcggc ggggacgaac ggtctgcgcg cccacctggg tacgacactg ctggcggtta
    21541 ccgcgcacgg cttcgggtcg attgcggtgg tgcgcacgaa ccccgatacc gatgccgtgc
    21601 gcgaagacgg cccggtggtg gtcggcgtcg atggcagcgc ggtgagcgag gccgcgctcg
    21661 gcgccgcgtt cgaggaggcg tcgcagcgcg gcgcggaact ggtggcggtg catgtgtgga
    21721 acgacgcgaa cttcggggag ttcgcggggg atccgtatct gttgttcctg gtgcccgata
    21781 tcgaggtgaa cgagcacgcg gtgctggccg agcgattggc ggggtggcag gagaagtatc
    21841 cggacgtcac ggtgacccgc agcgtggcga tgtcgagccc ggccgggata ttgcggaagt
    21901 ggtcggagtc ggcgcaactg gtggtggtgg gtagccgcgg gcgcggcgga tttcaggggc
    21961 tgctgctggg gtccacctcg aattcccttg tgcaacacgc aaattgcccg atcatggtag
    22021 tccatccggc gaaataggga gtgtgcgatg accgatgcgt tggccccgct ggagatcggc
    22081 acggcggaga tgatcgagga tctggatgcg tggtggcggg cggcgaacta cctgtcggcg
    22141 gggcagatct atctgctgga caatccgctg ctgacggaac cgcttgcgcc gcaccatatc
    22201 aagccgcgcc tgatcgggca ctgggggagc gtgccgggta tcacgctgac ctatgcgcac
    22261 ctcaaccgcg tgatcgtgcg gcggcggcag ccgatgctgt tcgtctgcgg gcccggccac
    22321 ggggccgcgg gactgaacgc ggcggcctgg ctggagggca cctacggcga acaccatccg
    22381 gaggccgcgc gcgacgccga cggtatgcga gagttgttcc ggcagttctc gtttccgggc
    22441 ggcgtgccca gtcacacctc gccgcacctg ccgggttcga tccacgaggg cggcgagctg
    22501 ggatactcgc tcgcccatgc gaccggggcg gcgctggaca acccggatct ggtcgtggcg
    22561 tgcatgatcg gcgacgggga ggcggaaacc ggtgcgctgg cgacgagttg gcacgcaccg
    22621 gcattcctga
//
