LOCUS       NZ_KV411303            20366 bp    DNA     linear   CON 12-FEB-2024
DEFINITION  Nocardia terpenica strain IFM 0406 scaffold1, whole genome shotgun
            sequence.
ACCESSION   NZ_KV411303
VERSION     NZ_KV411303.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardia terpenica
  ORGANISM  Nocardia terpenica
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 4641778)
  AUTHORS   Buchmann,A., Eitel,M., Koch,P., Schwarz,P.N., Stegmann,E.,
            Wohlleben,W., Wolanski,M., Krawiec,M., Zakrzewska-Czerwinska,J.,
            Mendez,C., Botas,A., Moris,F., Cortes,J. and Gross,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-APR-2016) Pharmaceutical Biology, University of
            Tuebingen, Auf der Morgenstelle 8, Tuebingen 72076, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 30-JUL-2014
            Assembly Method                   :: CLC NGS Cell v. 7.0.4
            Genome Coverage                   :: 118.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/12/2024 01:56:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,832
            CDSs (total)                      :: 8,760
            Genes (coding)                    :: 8,562
            CDSs (with protein)               :: 8,562
            Genes (RNA)                       :: 72
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 40 of 198
            Pseudo Genes (incomplete)         :: 174 of 198
            Pseudo Genes (internal stop)      :: 9 of 198
            Pseudo Genes (multiple problems)  :: 23 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:51:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4237580
            Orig. end                         :: 4257946
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KV411303.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20366
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="16"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     cand_cluster    1..20366
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20366
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:15366](+)"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..15366
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     gene            complement(694..942)
                     /locus_tag="AWN90_RS49265"
     CDS             complement(694..942)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS49265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_331713278.1"
                     /transl_table=11
                     /translation="MSIWFRIPSGTRRRPALYAESDFNAELVTQEFGWSSPAMVTDVYG
                     RSANRQAMKFLQQAWDASARPPAEPFLVPGQARGADS"
     gene            935..1294
                     /locus_tag="AWN90_RS49270"
     CDS             935..1294
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS49270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_331713279.1"
                     /transl_table=11
                     /translation="MDIQAGAGTGPTQHLSDTARVQCRASGGAGEMDQDVLVVDQVLDR
                     TELVEQIGVERADHVIGDRAEHPVDGVTVPGWGRWGVGLRASPVGVVVAADDMNVRVGA
                     LPAGMVPGQVQVAEP"
     gene            complement(1565..1942)
                     /locus_tag="AWN90_RS48135"
     CDS             complement(1565..1942)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS48135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_231951476.1"
                     /transl_table=11
                     /translation="MLTFATLTSTSAVVDLDRFTVRKVRHPDGRLSHWIFSPAGEVHRP
                     SLAVLTRHGTSTQETYAYSLVDHLNWLHVNSRSPDSVTFDDLRRYMNGVTGRPTVCMAW
                     SGAVRTASRWARRRRATSRRW"
     gene            2150..2800
                     /locus_tag="AWN90_RS19180"
                     /old_locus_tag="AWN90_19220"
     CDS             2150..2800
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0019239 - deaminase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025793.4"
                     /locus_tag="AWN90_RS19180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_19220"
                     /product="nucleoside deaminase"
                     /protein_id="WP_156674201.1"
                     /transl_table=11
                     /translation="MPELDAIWREADTAMLRCLELAHESFLSRGLPVGSVIGTGDGEEI
                     GEGRNRVYDPSGGPDRLQRTSIAHAEMNALASVDTTTDSSSLTLWSSHRPCLMCAAACE
                     FTGVGSVVFIAPDPSDAAVVRDPDGIDPEWVVVVNLLFLSGVAARSGPPSPTIARARWR
                     EPEVVALMGTDADTALRQQPLRAALIPLWTGITTAAQERLNHHGRGVGPSRSV"
     misc_feature    complement(2811..2825)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 23.2"
                     /tool="antismash"
     misc_feature    complement(3338..3353)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.06"
                     /tool="antismash"
     gene            4245..4997
                     /locus_tag="AWN90_RS19185"
     CDS             4245..4997
                     /codon_start=1
                     /gene_functions="regulatory (extras) StrR_like: StrR-like
                     pathway specfic regulators"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS19185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_231951478.1"
                     /transl_table=11
                     /translation="MFNGTAAEAMVLAVQLNVAHGLPLTRSDRAAAAVKMIDKYPQWSN
                     RMIATYVGLSPSTIGSLRPRSSDQIDQTNIRLGRDGRSRPTDPAASRQRVVEVLRRRPA
                     ASIRDIATEAGVSVSTVHDVRKRISSGMDPIARRSHKAKGNQPGQVSGQRADKNAANLV
                     VALANDPSLRLNEFGRQLLRCFHLHRVTLMEPNRAAEMVPNHCVGKVAELARIYANSWA
                     DLANLLECRISTDQASALKPQSLEDKHS"
     misc_feature    4758..4760
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    4923..4925
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    4962..4964
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5001..6017
                     /gene="aepX"
                     /locus_tag="AWN90_RS43635"
                     /old_locus_tag="AWN90_19225"
     CDS             5001..6017
                     /EC_number="5.4.2.9"
                     /GO_function="GO:0050188 - phosphoenolpyruvate mutase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="aepX"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR02320.1"
                     /locus_tag="AWN90_RS43635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_19225"
                     /product="phosphoenolpyruvate mutase"
                     /protein_id="WP_197696408.1"
                     /sec_met_domain="phosphonates (E-value: 1.1e-97, bitscore:
                     324.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 8.3e-59, bitscore:
                     197.0, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPKFTEFNGRTFQVPTYSTTNDLRRARLSGLLSERGCIRVIEAH
                     NPISAIVAEGAHVSASGPFSGEFDAIWSSSLTDSAVRGLPDIEILDWRIRLAAIDEIFA
                     VTAKPLIMDGDTGGLPEHFEYTVRELERRGVSAVIIEDKRGLKQNSLLGGSRLQEMESM
                     ERFCDKIRRGKATQVTQEFQIFARIESLILGEGMHSALQRADEYVNAGSDGIMIHSRDK
                     CPDDVMKFATEFRKTHPGVTLIAVPTTYNSVHADELAGAGFNIVIYANHLFRSSMKAMQ
                     DACRRILLNGRTAEVEEICVDLAEILNLARPVMPTADRLSAVRTGELENIDSYRHTL"
     misc_feature    5097..5099
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    5388..5390
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    5469..5471
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6303..7223
                     /locus_tag="AWN90_RS43640"
     CDS             6303..7223
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF017532.4"
                     /locus_tag="AWN90_RS43640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytanoyl-CoA dioxygenase family protein"
                     /protein_id="WP_082870940.1"
                     /sec_met_domain="PhyH (E-value: 2e-11, bitscore: 42.5,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEECMLRAGVSNISTASTASERDWQPLSDEQFCSYEKDGYLLLRS
                     VFNEAEVELGLAVVSDALAMPHPTIGQHASFADYSHTIRVRNAVDGLPGLDYFLDHPRL
                     VGPLMTLLNHSVHILGTEVFVRSTHADALEYWHTDGGEYLQRLQLAEGSPSLQVKAQIF
                     LTDVTKSNSGNFLLIPGSHRKIPNSRNMLCYMDELDEPLKQGILPEDAVEVKAAPGDVL
                     VFPYSLWHAVSKNVVRTRKTFIFRYGNLWHRPHDYLTQPQRVLDRMSPRLRRMFGDFGD
                     NVHPSDYYKPVDQGDIMAQGGNYGK"
     misc_feature    6318..6320
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    6624..6626
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    6876..6878
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    7264..7279
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.53"
                     /tool="antismash"
     gene            7669..8457
                     /locus_tag="AWN90_RS48140"
     CDS             7669..8457
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012341.4"
                     /locus_tag="AWN90_RS48140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_231951568.1"
                     /transl_table=11
                     /translation="MNIIDGGLCPSSKVPHIEFLLFPDPDVQLLDAVETSIRVRDYARE
                     VCYRRGYEAATSQQGAISVPLQSCTEGMDIILAVLQELGVESGFRLGLDMAASDVWRNG
                     KYQFPWTNRALSADALLDTYLEWIPRYSLRYLEDGFSASAMSEFTVLTSKAGDMMIAGD
                     DLFASNVSRVTAGVQGGWANAVVVKPNQAGTVSAAIRAAEATRNNGATLVISQRSGENG
                     GSFISSLAIACGARYIKVGGPARMDRIAKINELLTTLAPK"
     gene            8496..9683
                     /locus_tag="AWN90_RS43650"
     CDS             8496..9683
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="AWN90_RS43650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_171982702.1"
                     /transl_table=11
                     /translation="MGVVEFGDIAYLVSLSASLYLYGGSSMHVAYGMAAYSIGSLVGSW
                     VGGILVDAIPARRWMLIGNTCASILVFTNVFAASLPVLVIYAAVVSIASRAMLVSQQSC
                     LPLIDSVSLLRANSVVMICRRIGQLSGPGLAGILVARGDLHLVYVLNAATFAVAAIVGF
                     AAVPAGTATTKKKTGESKRDFSYILRIPAVRSSFVVNCVTGILAGTSSVSIVVYTGSVL
                     HGGAREFGLISAFTGAGAVLGTIVAPLVGRMMPIKMSVASTVVSAGVALSILPFVMWLP
                     GAAALRAVNGYAVNVIFILLMANLQSHAPKEMYGRLIATTRSGQDSLMILFIMVSGVLV
                     QAVGVRVVLVFVGSLAVLCAALIGLSKNPFDWEPADRVITDDSRWRRPGTEQSVG"
     misc_feature    8676..8678
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9159..9161
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9333..9335
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9486..9488
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            9688..10656
                     /locus_tag="AWN90_RS43655"
     CDS             9688..10656
                     /NRPS_PKS="Domain: Aminotran_4 (70-287). E-value: 1.2e-27.
                     Score: 89.1. Matches aSDomain:
                     nrpspksdomains_AWN90_RS43655_Aminotran_4.1"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013247.4"
                     /locus_tag="AWN90_RS43655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminotransferase class IV"
                     /protein_id="WP_082870943.1"
                     /transl_table=11
                     /translation="MSGLNKAGNSMDNCLDNVSGRSVPNNFSWVDGEWVANMSIPTRTT
                     AVLYGASVFDNCRAWRGADCASVYGLVDHIERFRRSATEALLDLPVKDSDLTDGIAAVL
                     SCSPPNKFVRVRMLAFGADEELCSRRASVVIFALPVEGYAPLNPRLVTSTTRRRVSGDL
                     PRTLKSPSGYLFVRREVARARVAGYDDVVLVNEHDRISEATRSNLVIVNGSVFSSPPTS
                     EGALPGVTKRIVRQLVTAAGFRWESRPIDCQELTSAEGVLLTSSSLGVTAAQSVNDRQL
                     ATTEAMQTICARYADLPFAESDHASLSVLPLRDQAEKVSFG"
     aSDomain        9898..10548
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AWN90_RS43655_Aminotran_4.1"
                     /evalue="1.20E-27"
                     /label="AWN90_RS43655_Aminotran_4.1"
                     /locus_tag="AWN90_RS43655"
                     /protein_end="287"
                     /protein_start="70"
                     /score="89.1"
                     /tool="antismash"
                     /translation="LVDHIERFRRSATEALLDLPVKDSDLTDGIAAVLSCSPPNKFVRV
                     RMLAFGADEELCSRRASVVIFALPVEGYAPLNPRLVTSTTRRRVSGDLPRTLKSPSGYL
                     FVRREVARARVAGYDDVVLVNEHDRISEATRSNLVIVNGSVFSSPPTSEGALPGVTKRI
                     VRQLVTAAGFRWESRPIDCQELTSAEGVLLTSSSLGVTAAQSVNDRQLATTEAM"
     gene            10653..11447
                     /locus_tag="AWN90_RS19190"
                     /old_locus_tag="AWN90_19230"
     CDS             10653..11447
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1204: transketolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012670.4"
                     /locus_tag="AWN90_RS19190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_19230"
                     /product="transketolase"
                     /protein_id="WP_067583022.1"
                     /transl_table=11
                     /translation="MTLDEALSTLRFQTLTMIADAGSGHPGSSLSCLHILAALFHKVLR
                     GVASQDRDRDRLVLSKGHAAPALYVMLRDIGVLASDDIFGLRSIGSRLQGHPDRLRTPG
                     VEASSGSLGQGLSMGVGLGLGLRHRNSPARVYVLLGDGELQEGQVWEAAALAGHLGLAN
                     ITAIVDRNRHQHDGPTESISTLEPLADRWQAFGWEVDDVDGHDVQELAAAMVRRNSGPR
                     VLIAHTAKGFGVPFMEGDSPWHSVKDVEVLRRYVVELEAYRA"
     misc_feature    10695..10697
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    10950..10952
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11440..12366
                     /locus_tag="AWN90_RS43660"
     CDS             11440..12366
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014798.4"
                     /locus_tag="AWN90_RS43660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transketolase C-terminal domain-containing
                     protein"
                     /protein_id="WP_171982703.1"
                     /transl_table=11
                     /translation="MRNAFGIALIELKEDFPELVVLDGDNATSTQTQLFSNRFPEAFLN
                     VGIAEQNMVGIAAGLALAELRPVASAFASMLVNRALDQITHAVAYQKLGVVLVGHYAGL
                     SGGREGACHHSISDIAALRSVPNLSIVLPAADEDVLPLLRLAVQSGQPTYLRLSRQSAS
                     RLPRPDRGSPMEGWCYWGNDEPEILIVTCGPIAAMAVDLQPELGANTGVLNIYRMKPFP
                     DAGLWETTHRARAIVTVEEHSVVGGLGSMMSEWTAQHKPVVNVPLGIADEFTVSGDHSE
                     LLKLYGISPTNILNAVHLAVHRMERGR"
     misc_feature    11617..11619
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12368..13567
                     /gene="aepY"
                     /locus_tag="AWN90_RS19195"
                     /old_locus_tag="AWN90_19235"
     CDS             12368..13567
                     /EC_number="4.1.1.82"
                     /GO_function="GO:0033980 - phosphonopyruvate decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aepY"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014985094.1"
                     /locus_tag="AWN90_RS19195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_19235"
                     /product="phosphonopyruvate decarboxylase"
                     /protein_id="WP_067583024.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.4e-11, bitscore:
                     42.3, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.2e-15, bitscore:
                     55.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFTADSLLIELTARGVGEVTGVPCSYLTPLINRVASNDRVSYFPA
                     THEGEAVAIAAGSWLAGAITCVISQNSGLGNMVNPLTSLCHPCRIPVPMIVTWRGEPGV
                     ADEPQHELLGAKTPDLLTLIGVGHSVLPSKPERLSATVGLGWEAMQRDELPYAFILRGG
                     SIAPEALSETWSTGAAESVVMGGRDRPRKCSRRIDALDTLLSAVVDSAAIVSTTGKTSR
                     ELFTLADRPQHFYLVGAMGSASAVGLGVARHTSTPVVVVDGDGASLMRMGTFATVGAAG
                     PPSLIHILLDNQVHDSTGGQRTQAEYVNFPAVAAACGYRWVFDCADLLEFEFAVQRAQT
                     TQGPVFIYLRIKPGSIENLGRPTVRPSDVARRFRDFVKASKAGWDTAQTMEEAHCIEQL
                     "
     misc_feature    12797..12799
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14116..15366
                     /locus_tag="AWN90_RS43665"
     CDS             14116..15366
                     /NRPS_PKS="Domain: Aminotran_5 (37-404). E-value: 1.6e-66.
                     Score: 216.7. Matches aSDomain:
                     nrpspksdomains_AWN90_RS43665_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012488.4"
                     /locus_tag="AWN90_RS43665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_197696409.1"
                     /sec_met_domain="Aminotran_5 (E-value: 2e-59, bitscore:
                     199.4, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.4e-09,
                     bitscore: 34.9, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYDSVTRFPGPDYTDIARISDLDLRMIRDDTPGTECVIHLNNAGA
                     ALMPRPVIDTMREHITLESQIGAYEAAEAMEGEIRASYTSIAQLLGCSANEIAITDSAT
                     RAWGLAFGSIQFHPGDRILASPVEYGSNYLALLHSVRHLGIEVEILRVTESSIIDTAAL
                     RETMDERVRAILVTHVPSHSGVINPIAEIGEVARKYGSLYMVDACQSVGQIPISVSEIA
                     CDFLSGCGRKYLRGPRGTGFLYMRPDISHEIEPPMLGLDGARWLGGTRYEIAPGAKRFE
                     TWEANTVAKLGLGAAVDYSLTLGIHAIRERVTTLADYLRRCLTSVSDVHLLDQYNADGL
                     AGIVGFDVPGRNLYEIRNQLKKKRINVWISLSNTACVDMERRKLNECIRVSVHYYNTIE
                     EIDTFCNSLLDSIDGRV"
     aSDomain        14227..15327
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AWN90_RS43665_Aminotran_5.1"
                     /evalue="1.60E-66"
                     /label="AWN90_RS43665_Aminotran_5.1"
                     /locus_tag="AWN90_RS43665"
                     /protein_end="404"
                     /protein_start="37"
                     /score="216.7"
                     /tool="antismash"
                     /translation="IHLNNAGAALMPRPVIDTMREHITLESQIGAYEAAEAMEGEIRAS
                     YTSIAQLLGCSANEIAITDSATRAWGLAFGSIQFHPGDRILASPVEYGSNYLALLHSVR
                     HLGIEVEILRVTESSIIDTAALRETMDERVRAILVTHVPSHSGVINPIAEIGEVARKYG
                     SLYMVDACQSVGQIPISVSEIACDFLSGCGRKYLRGPRGTGFLYMRPDISHEIEPPMLG
                     LDGARWLGGTRYEIAPGAKRFETWEANTVAKLGLGAAVDYSLTLGIHAIRERVTTLADY
                     LRRCLTSVSDVHLLDQYNADGLAGIVGFDVPGRNLYEIRNQLKKKRINVWISLSNTACV
                     DMERRKLNECIRVSVHYYNTIEEIDTF"
     misc_feature    14299..14301
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            15370..16293
                     /locus_tag="AWN90_RS43670"
     CDS             15370..16293
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013088.4"
                     /locus_tag="AWN90_RS43670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DMT family transporter"
                     /protein_id="WP_082870945.1"
                     /transl_table=11
                     /translation="MTLKRIANFGPDASRVLSYGCLIAAAVLFGCTGVLVKNVFKPPYS
                     TLSLISLRAVVSLLVMLPIMVYRGLSDLRIDRTQFRALLGLGLWLLLVNVTFFCAINLV
                     PVAEVIALQYTAPIVVLLVEILKKAQPMTLSAGAVVVACTLGIVLLSEVRSVGLGGKGT
                     AGFLLGVASGISFAFYNLQGKYSSAIGLNARTTTFYSILFSVVPCLPFLPFLKIDFFVE
                     SWQTFFWLIVVSILGCGLPCLLLFKGLGGVSAFPATVVGVLEPVVAAICAYVVLHENLS
                     LQQMAGGVVVVCAAVYAPRSVSRRYR"
     misc_feature    15376..15378
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16336..17100
                     /locus_tag="AWN90_RS45735"
     CDS             16336..17100
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019846.4"
                     /locus_tag="AWN90_RS45735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_156674202.1"
                     /transl_table=11
                     /translation="MIIEHHPAELLDTYLEICSGEQLFVSQALAAFDAVDSLGSMLDCA
                     VGTGFGTIPLLRSGLPLVCSDGSAEMIERFHLNCRRAGLGNRSILAQWADLPNYFPAVF
                     DLVMCRGNSLAYADSWDDEEAPNPDPERIGRHLRGMAGALRSGGALLLDIPDTRDITSD
                     VSYVTENGGLTRDGLRVAIVDEVHVSLAHRLRRWRTTMTIDGTVYGFERTSHLIQLEEV
                     RSDLKACGFDEVKTLEIRNIRDNFISLLAIKL"
     misc_feature    16852..16854
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    17011..17013
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17134..18195
                     /locus_tag="AWN90_RS43675"
     CDS             17134..18195
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019121.4"
                     /locus_tag="AWN90_RS43675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_082870946.1"
                     /sec_met_domain="Dala_Dala_lig_N (E-value: 3.1e-22,
                     bitscore: 77.1, seeds: 508, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 4e-05, bitscore: 21.3,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 1.3e-07, bitscore:
                     29.8, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 6.9e-35,
                     bitscore: 118.4, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIVVVCGGVSSERSVSMSSGLTVTKALIAAHHDVVVLDPAQQPS
                     VLIGGSGSGTDHLFDLEIQAELPGSGVGRCGASFLDSLMAPDVWDQLRGADIVFVALHG
                     GWGEDGHVQALFEMAGIPFTGASSVACNFSYRKSRSLQLLKAAGVPTPEHVVWESQVRS
                     VPADAIAMVNRGPVVVKPDTEGSSVGAHLVDNAVQIESIKNNTADLVIGPYLPGREFTV
                     GVIGDTVLPPVEINNIRALFDYQSKYRREVSCQCPAPVDDALNERLKKYALSAHQALAF
                     DSTMYSRIDFRCDADENPFVLEVNALPGLSPVSLLPLAAMQLGWSYLELIESLINLKLS
                     SIRRCRSVSASSG"
     misc_feature    17563..17565
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(19120..19842)
                     /locus_tag="AWN90_RS45740"
     CDS             complement(19120..19842)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS45740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_156674203.1"
                     /transl_table=11
                     /translation="MTGTSLYSNRTIIRASAVLCATAAVVTACANQPGQPTASPSAPTT
                     TARPKSPYPPVTFTWDFAVPLTGQEEAAARFAAETAMADDQFMWADHYEPDLERAYNER
                     VTRTYIGSRSSWEATQSKWPATGGMLWRVVGTTPAEDGYRVTLCQFDTPGTYSLIDDKL
                     VKDPGNRSHAAEALTVVSTTKPSAADPYQTPAPRTLVTAIEPPGAPNESPSVHCDKFAP
                     EPFVQTPPPPITPAPGQK"
ORIGIN
        1 atccggccga ggtcgcacgt ctgcacgcct tgcaccggct cccacaaccg ccgcccctgg
       61 atccccgaca accccacaaa cgccaaagct caaccaccac aaggagaacc agcatcatga
      121 gcaaatccga ttacacagat cgcattgaga acaacccacc tcgacggggt tgaggtccgg
      181 gcgtaggccc gtagctggcc gaccgtgaac cagtcccggt cggcgacata gctgcgtatc
      241 ccgaggccag gtgtgtattc aggtttgtcc cagaccagca taaccttgct gccggtgagc
      301 gtcggcgagc aaatcccggt agttggtcca cgcgaaactc tgtctggccg aacggcttcg
      361 gtcgtagcag tgcggccgat agatcagccg ggaccagtcg ccgggccgat agcaacacag
      421 cgcgctcttt gacctcggcg tatctgcgtg catgggcgac gcaaagctgg gccgacggcg
      481 cggtcgcatg cagcccgccc tcgcagcctt cgacacggca atgccaaccg taggtggggt
      541 ggtgcggcgg aaactcgacc ggttccgcca acagccactc cggaaactgc tgactgacaa
      601 tgtcgtagcg gccatccggg ctcaacccca gatactcggc cgccgagtcc ggaaccgacg
      661 tcaacgaggt gctcgcagcg atgtccggcg tcgtcacgag tcggctccgc gggcctggcc
      721 cggcaccaga aacggttcgg ccggtgggcg ggcgctggcg tcccatgcct gctgcaggaa
      781 tttcatcgcc tgccggttgg ccgaccgtcc gtagacgtcg gtgaccatgg ccgggctgga
      841 ccagccgaac tcctgggtca ccaactcggc gttgaaatcc gactcggcat agagcgcggg
      901 ccgccgcctt gtgccggaag gaatgcggaa ccagatggac attcaggccg gcgcgggaac
      961 aggcccgacg cagcatcttt cggacaccgc ccgtgtgcag tgccgcgcca gcggtggcgc
     1021 cggtgagatg gaccaggatg tgctcgtggt cgaccaggtg ctggatcgga ccgaactcgt
     1081 cgagcagata ggcgtggaac gtgctgatca tgtcattgga gaccgcgcgg agcaccccgt
     1141 cgacggtgta accgtcccgg gttggggtcg ctggggcgta ggacttcgcg caagcccggt
     1201 tggggttgtc gttgcggccg acgacatgaa cgtgcgggtc ggcgcgctgc ctgcagggat
     1261 ggttccgggt caggtgcagg tcgcagaacc gtagcccgca gagcccgccg acgcgcagac
     1321 caccgtcgtg caaccaggtc acgatcatga cgtcccggac tgtcggcaac actcccggct
     1381 cgaacaacgc ctcgacgacc tcatcgagca gaaaccgacg ctgacgcgaa tccttctgta
     1441 gggcgagctg attcgtctcg accgaccgcc gaccacgacg ggcgaagctg cgccccgagg
     1501 tcaacgcctc gaccagctcc ggccgaacct cgccggtcac ctgcagcgac agatagtagg
     1561 accttcacca ccgtcgcgac gttgcccgcc gccgacgtgc ccagcggctt gcggtccgga
     1621 cggcgccaga ccaagccata cataccgtcg gcctgccggt gacgccattc atgtagcggc
     1681 gcaggtcatc gaaggtcact gagtccggac tgcggctgtt cacatgcagc cagttcaggt
     1741 gatcgaccag gctgtaagca taggtctcct gcgtcgacgt cccgtgccgg gtgagcaccg
     1801 ccaacgacgg ccggtgcacc tcaccggccg gagagaagat ccaatgcgac aaccggccgt
     1861 cggggtggcg gaccttccga acggtgaacc gatccagatc cacgaccgcc gacgtggagg
     1921 tgagtgtggc gaatgtaagc atcaatccct gttcgccaca gagcaattca gggatgggta
     1981 cgaatatcgc ggacgccggt tacgtggggg ctaagcgaca gatgctcggg cgagtgaaac
     2041 cggatcttct ccggaaagcg aattcttttg agcaactgag tatccgagga cggaacaacg
     2101 caccggcatc tcgcccgaca ccgtggagcg ctctgcgaca ctggtgttcg tgcccgaact
     2161 ggacgccatc tggcgtgaag ccgataccgc gatgctccgg tgtctcgagc ttgcccacga
     2221 gtcgtttctt tcgcgcggac tgccggtcgg ttccgtcatc ggcaccgggg acggtgaaga
     2281 aatcggggaa ggtcgcaatc gcgtctacga tccttccggc gggcccgacc ggctgcagcg
     2341 cacctccatt gcgcatgccg agatgaacgc cctcgccagc gtcgatacca cgaccgattc
     2401 gagcagcctc accttgtggt cgtcacatcg gccgtgtctg atgtgtgcgg cggcatgcga
     2461 attcacgggt gtgggcagcg ttgtcttcat cgcccctgac ccttcagacg ctgcggttgt
     2521 ccgagacccg gacgggatcg atccggaatg ggtcgtggtt gtcaacctgc tgttcctgtc
     2581 tggcgtggcc gcgcgttcgg gtccgccgtc gccgacgatc gcgcgcgccc ggtggagaga
     2641 accggaggtc gtcgccttga tggggaccga cgctgacaca gctcttcgac agcagccgct
     2701 tcgcgctgcc ctgatcccgc tatggacggg cataacgacg gcagcgcagg agcgcctcaa
     2761 ccaccatggg cgcggtgtcg gtccatcccg atcggtgtag tcgatcatca agggccggtc
     2821 tgtccgcgtt ccgatccgcg gatatcacgc aaagtgtgcc tgatccagca ttcgaccggc
     2881 attgacgttt cgctcgaaga tggtccagca gcctccaacg ctcagcacca tggtctgggg
     2941 gccgacactc ttgcgtgctg gtggatccgg ccgcgaacgc gaagagcagg gagcccgaag
     3001 agatagggga tacacacaag actgctcggc tgaggggtga cgaatgtttc gcgtcctgtt
     3061 cgaggtggtc actcggagcg ccgtgcggac tgactggacc atggggcgac cgaaccgcga
     3121 gcggtgatgc caacagtcca tgtcattgat cgcgggccag cggggccgac tgatccctcg
     3181 gaggttcagt gcgactgagg tcactcatcg atccggacaa gaattctcct gcgattctcc
     3241 gggtgtgtga ctcgtagatc gccgtataag gccagttcaa cgacagtgat tctagaatca
     3301 gcgtagaaac gctctcagaa gttcgattga cattccctgt gatgcgcctt acattcacct
     3361 gagatggcac gagcgggcgg cggaagaaaa ggctgcacgc gccgataggt gtgcgtgatt
     3421 caagttttca ctcgctgaag ctcgctacat tgttcccctc tgtgtgctgc tgacccaatg
     3481 aaaggaattg ggcaatgggc atgttgcata gctactccgc agggcaattc ttgcctcggc
     3541 cggattttca ggcccgtcaa acgattcgcg accgcgcggg tgagtgcgct tacagtaatc
     3601 atggatgccc ctgcgcattc tcaacggatc gacgtatgta tcggatgatt gcgtatcctc
     3661 cgcccgaacg agtcgacctg cgatctcctc gcggagaagc gtggcatggg gagtgacttt
     3721 acacgctttc ggcagtgttt gtgcgaggag ctgcgctgtg ccgcacctgc atatatgccg
     3781 ggagcgcggt agaacattga ttacctacat ggagaacgga cgggagtgac cgggagtagc
     3841 aagctggttg gcgcgggtgt tccgcagttc gccagcgagt ttcatatcgg ttcgtgatgc
     3901 cttctgagca gaaaacatta taaccggaat atgcaggggg agaaatctgc atgaacttag
     3961 atgtagaaac gtgtaagggc ttgagcgtcg acgagccgaa ttgtgcaacc ctaattcgaa
     4021 tagattggga ccaggtcccg atcgcggatt tggcactgga taagctcaag ggtgtaatgt
     4081 ttgtccgtgg tataggaacg gatcccgagc acgtgagcaa tttgtccgag gtgctggata
     4141 accttccacc aattactgtt cactcggaaa caatgtccgt gatagatggt atgcatagag
     4201 tcgccgccgc tagactaggg ggaaggtcgg cagttcgtgc gcgtatgttc aacggaacag
     4261 ccgcagaggc aatggtgttg gcagtgcagt tgaatgttgc tcatggcctt ccgctgacac
     4321 ggtctgaccg cgcagctgcc gcagtgaaga tgattgataa atatccacaa tggtcaaatc
     4381 gaatgattgc gacgtacgtt ggcttgtcgc ccagcactat cggatccctt cgcccacgtt
     4441 cgtctgatca gatcgatcag acgaacatcc gtctcggacg cgatggtcga tcgcgaccaa
     4501 cggatcccgc cgcaagccgg caacgcgtag tcgaggtctt gcgtaggagg ccggcggcat
     4561 ctatccgcga tatcgcgacc gaggcgggcg tgtcggtatc gacagtccac gatgtccgca
     4621 aacgaatatc cagcggcatg gaccccatcg ctcgccgatc ccacaaggcc aagggcaacc
     4681 agcctggtca ggtatcaggg cagagagcgg acaaaaatgc cgccaatctc gtagtcgcgc
     4741 tggcaaacga tccttcttta cggctcaacg aatttgggcg ccaactcctc cgatgcttcc
     4801 atctgcaccg agtcactttg atggaaccga atcgtgctgc cgaaatggtt ccgaatcact
     4861 gcgtcggtaa ggtagctgag ttggcccgaa tctatgccaa cagctgggcc gatttggcga
     4921 acttactcga atgtcgtata tcgactgatc aggcaagtgc cttaaaaccg cagtcgcttg
     4981 aggataagca tagttgaaat gtgactccaa agtttactga gttcaatgga aggacttttc
     5041 aggtgcctac ctattcaaca acaaacgatt tgcgccgggc gcgcctttct ggattgttaa
     5101 gcgaaagagg ctgcatccga gttatagaag cgcataatcc aatttcggcg atcgtcgcag
     5161 aaggcgcgca tgtcagcgcc agcggaccgt tttcgggaga attcgatgcg atctggtcta
     5221 gttctttgac cgactccgca gtgcgcggct tgccggatat tgaaattctc gattggcgta
     5281 ttcgactggc ggccatcgac gagatcttcg cagtgacggc caagccgcta atcatggatg
     5341 gcgatactgg cggactcccg gagcattttg agtacacggt tcgtgaatta gagcgacgcg
     5401 gtgtatctgc agtgatcatc gaagataagc gcggcctcaa gcagaattcg ctacttggtg
     5461 gatctcggtt acaagagatg gaaagtatgg agcgtttctg cgacaagata cgacgcggta
     5521 aggccacgca agttacgcaa gaattccaga tattcgcgcg catcgaaagc ctgattctgg
     5581 gagagggaat gcattctgca ttgcagcggg ctgatgaata tgtaaacgcg ggcagtgacg
     5641 ggataatgat ccatagtcga gacaaatgtc cagacgatgt aatgaagttc gcgacagagt
     5701 ttcgtaagac tcaccctgga gtcacgctga tagccgttcc aactacgtac aacagtgtgc
     5761 atgcggacga gcttgccggg gcaggtttca atatcgtcat atacgccaac catctgttcc
     5821 ggtcttcgat gaaggccatg caagatgcat gtcgaaggat cctcttgaat ggcaggactg
     5881 ccgaggtgga ggaaatttgt gtcgatctgg ctgaaatcct gaatctggcc cggccggtca
     5941 tgcccacagc ggaccggctc agcgctgttc ggacgggcga actcgaaaat attgactcct
     6001 atcgccacac tctataaatt aattctgtgg ctgccacgag atgtaagtag tagccatttt
     6061 taggaatcat cgaagaaatg gagaatggaa atgtctatct ctgttcgcgt caccgaggat
     6121 cgagttattc tgagcgaaga ctcgggtgag aatggaaagc ggcaggagat cggtccagtc
     6181 tgcgcttcct tcaagcagtt catttcggag gttaaggaag gaaagtacga caacctcgtc
     6241 tagatagtca tcggctgggt ggctcacgcc acccagccga ccctgggcga aggttaaagc
     6301 ggatggagga atgcatgtta cgggcgggcg tttcgaatat atcgacggca tcgacagcat
     6361 cggagcgcga ctggcagccg ctatccgatg aacagttttg cagttatgaa aaggacggat
     6421 atctacttct ccgaagtgtt ttcaatgaag cggaggttga gctcggccta gctgttgtgt
     6481 cggatgccct ggctatgccg catccgacaa ttggtcagca tgcaagcttt gccgactact
     6541 ctcacacgat ccgagttcgt aatgcggttg atggcttgcc gggcctcgac tactttctcg
     6601 atcatccacg gcttgtgggg ccattaatga ccttgctgaa ccatagcgta catatcttgg
     6661 ggactgaggt atttgtccgc tccactcatg cggatgcttt ggagtactgg cacaccgatg
     6721 gcggcgaata tctacagcgt ctgcagttgg ccgaaggcag cccgagcctt caagttaaag
     6781 cacaaatatt tctcaccgac gtgacaaaat cgaatagcgg aaacttcttg ctgataccag
     6841 ggagccatcg taagataccc aactcccgga acatgttatg ctacatggac gagctggatg
     6901 aaccactaaa gcagggaatc cttccagagg acgccgttga ggtgaaagca gcacctggcg
     6961 atgtactagt ttttccgtat tcgctatggc acgctgtatc gaaaaatgta gtccgtactc
     7021 gaaagacgtt tatatttaga tatggaaatt tgtggcaccg cccgcatgat tatctaactc
     7081 aaccgcaacg agtccttgac cgtatgtcgc cgcgtttgcg ccgtatgttc ggagactttg
     7141 gagataacgt tcatccctcc gactattata aacctgtcga tcaaggcgat ataatggctc
     7201 aaggcggaaa ttatggcaag tgagaattct ataaccaagg tgattgctcg tggcctgtac
     7261 gactcgaatg gacgtgcggc cgttgaagtt actcttgtcg acggggcagg acggagctcg
     7321 agtgcgctag ccccgcgcgg ctcgagcgtt ggtgagtatg agccggcaca tctggaggat
     7381 gctgcttcgc agcctcgact tagggcggtg gcgcctgctg tgcgcgcagt agcacagcag
     7441 gtagagccag cgctggttgg actcgacgcg tcagatttga ccgcggtaga tcgccggctc
     7501 gacgatctgg acccacctcc atcacgaaag gtcataggcg gcaatacaac catcgctaca
     7561 tccatggctg tagcacaatt gggcgcgctc cagcgttcgc tcccgctgca cacacacctg
     7621 cgggacttcg tcggcctacc ggaagccgac cgacctccgt tgcctgccat gaatattatt
     7681 gacggtggcc tttgtcctag ctcgaaggtt ccgcacatcg aatttctctt gtttcctgac
     7741 ccagatgttc agctgttgga cgcagtggag accagcatca gggtccgtga ctacgcgcga
     7801 gaagtgtgct accggagagg atacgaagct gcgacgagcc agcagggtgc catttccgtg
     7861 cctctgcagt catgcacgga ggggatggat attatcctcg cagtcctgca ggaactcggg
     7921 gtagagtctg gattccgcct cggtctggac atggcggcgt cggacgtttg gagaaacggt
     7981 aagtaccagt tcccgtggac caatcgcgca ctgtcggctg atgcactgct tgacacttat
     8041 ctggaatgga tcccgcgata tagtcttcgc taccttgagg acgggttcag tgcctcggcg
     8101 atgagcgaat tcaccgtgct gacatcgaag gcgggagaca tgatgattgc cggtgacgat
     8161 ctctttgctt cgaacgtgag ccgtgtaacc gctggcgtgc aaggagggtg ggcgaatgct
     8221 gtcgtggtaa agcccaatca ggccgggact gtttcggcgg cgattcgggc tgcggaggcg
     8281 acacggaaca atggtgcgac attggtaatt tcgcagcgca gcggggaaaa cggcggatcg
     8341 ttcatcagta gtctggcgat cgcttgtggt gcacggtaca tcaaagtcgg aggtcccgcg
     8401 cgtatggatc gcatcgcaaa gatcaacgaa cttctcacca cactggcacc gaaatgatgg
     8461 caatacggcc acggcttgcc gttgtcgctt tggcaatggg cgtggtcgag tttggtgaca
     8521 tagcttatct ggtaagcctt tcggcctcgc tgtacctgta cggtggttcg tcgatgcatg
     8581 tcgcgtacgg gatggcggcg tacagcatcg gcagcttggt aggatcgtgg gttggtggca
     8641 ttcttgtcga tgcgattcca gcacgacgct ggatgttaat cggtaataca tgcgcaagca
     8701 ttcttgtttt taccaacgta tttgcggcgt cgctgcccgt cctcgttata tacgccgcgg
     8761 tggtcagcat tgcatcgcgg gccatgctgg tcagtcaaca gtcctgcttg cctttgattg
     8821 attcggtgag cctgcttcgc gcgaattctg tcgtgatgat ttgccgcagg ataggacagc
     8881 tttcgggtcc ggggctggcg ggaattcttg tggcccgcgg cgatcttcat cttgtgtacg
     8941 tgctgaatgc ggcgacgttc gcggttgccg ccatcgtagg ctttgcagca gtgcctgcgg
     9001 gaacagcgac tacaaagaaa aaaacgggtg agagcaagag ggatttctca tacatcttgc
     9061 gaatacccgc tgtacgctcg tctttcgtgg tgaactgtgt aaccgggatt cttgcgggta
     9121 caagtagtgt ttcaatcgtt gtgtacaccg gatcggtgtt acacggtgga gcacgggagt
     9181 tcggtctcat ctcagctttc accggtgcgg gtgcagtact gggtacgatt gtggcgccgc
     9241 ttgttggaag aatgatgcca attaaaatgt ctgttgcttc gacagtcgta tccgccggcg
     9301 ttgcgctgag tattcttccg ttcgtgatgt ggttacctgg agctgccgcg ctgcgcgcag
     9361 tgaacggcta tgcagtgaac gtcatcttta ttcttttgat ggcgaacttg cagagccatg
     9421 ctcctaaaga gatgtatggt cgtctgatcg ctacgacacg aagtggtcag gattccctga
     9481 tgattttatt catcatggtg tcaggcgtac tggtacaggc ggttggagtt cgcgtggttc
     9541 tggtctttgt gggtagtctc gcagttcttt gtgctgcttt gattggcttg tcgaagaacc
     9601 cgttcgattg ggagcccgcc gacagagtaa ttaccgacga tagcaggtgg cgccgacccg
     9661 gaacagaaca atcggtcgga tgacatcatg agtggactga ataaggcagg taactcaatg
     9721 gataactgtc tcgacaacgt cagcggcagg agcgtgccga ataatttttc ttgggtggat
     9781 ggtgagtggg tggccaatat gtccataccg acacgaacca cggcggtctt gtatggcgct
     9841 tcggttttcg ataactgccg tgcctggcga ggtgcggatt gcgcatcggt ctacggactg
     9901 gtcgatcaca tagaacgatt ccgtcgttcg gcgaccgagg ccctgctcga tctgcccgtg
     9961 aaggatagtg atctgactga tgggatcgct gcggtgttga gctgtagccc tccgaataaa
    10021 tttgtgcggg tgcgcatgct cgccttcgga gcggacgaag aactgtgctc acgccgtgca
    10081 tcagtcgtta tctttgcact accggtagag ggttacgcac cgctgaatcc tcgcctggtc
    10141 acatctacta cccggcgtcg ggtatccggg gatctgcctc gcacgctgaa gagcccgagc
    10201 ggatatctgt tcgtccggcg cgaggtggca cgagcccgtg tcgccggata cgacgacgtt
    10261 gtccttgtta acgagcacga ccggatatca gaagcaacgc gctcgaatct cgtgatagtg
    10321 aatggctccg ttttcagtag cccgccgact agcgagggcg cgctgccagg agtgacgaag
    10381 cgaatcgtgc ggcaactggt gactgctgca ggcttccgct gggagagtcg cccaatcgac
    10441 tgccaggaat tgacctcggc tgagggagtg ttgctgacca gttcgtcgct cggtgtgacg
    10501 gcagcacagt cggtaaatga tcgacagttg gcgacaaccg aagccatgca aactatctgc
    10561 gcacgctatg ctgacttgcc gttcgccgaa tccgaccacg cgtctctgtc ggtgcttccg
    10621 ctgcgtgatc aggcggagaa ggtgtcgttc ggatgacact cgacgaggcc ctctccacat
    10681 tgcggttcca gacattaacg atgatcgccg atgccggctc tggccaccca ggaagctctc
    10741 tgtcatgctt gcatattctc gcagcacttt ttcataaggt cctccgcggc gtggcatcgc
    10801 aggatcgtga ccgcgatcgc ctggtgctct cgaaagggca tgcggctccc gcgctctatg
    10861 taatgctgcg cgatatcgga gtgctcgcat cggacgacat atttgggttg cgtagtatcg
    10921 gttcacggct gcaggggcac ccggatcgat tacgtactcc aggtgtcgaa gccagctccg
    10981 gatctctcgg acagggtttg tctatgggcg tcggcctggg gctcggccta cgtcatcgca
    11041 acagtccagc ccgcgtttat gtccttctag gcgacggcga actccaggaa gggcaggtct
    11101 gggaagccgc cgcgttggca ggtcatctcg ggctggctaa cattacggcg atagtcgatc
    11161 gtaaccggca tcagcacgat ggtcccacag aatcgatctc gacacttgag cccctcgccg
    11221 accgctggca ggcgttcggc tgggaggtcg atgatgtaga cggccatgac gtccaagagc
    11281 tggcggcagc gatggtacgt cgaaatagcg gtccgcgagt cctgatcgcg catactgcaa
    11341 aggggttcgg tgtgcctttt atggaaggag attcaccctg gcattcggtc aaggatgtag
    11401 aggtcctccg ccgatacgtc gttgagttgg aggcataccg tgcgtaacgc gtttggtatt
    11461 gcgctgattg aattgaaaga agactttcca gagttggtgg tattggatgg tgataatgct
    11521 acctcgacgc agacccagct gttttctaac cgctttccag aggcgttcct caacgtaggt
    11581 attgcagagc aaaatatggt cgggatcgcc gccggattag ccttggcaga actccgaccc
    11641 gtggcctcgg ctttcgcctc gatgctcgtc aatcgggcac tggaccagat cacacacgcg
    11701 gtggcctatc agaagcttgg cgtagtactt gtcgggcact acgccggcct atccggcggt
    11761 cgtgagggtg catgtcatca ttccatcagc gacatcgcgg cgctgcgttc ggtcccaaac
    11821 ctgtcgatcg tcttgcccgc ggcggatgaa gacgtactac cactgctacg cctggctgtg
    11881 cagtcgggac agcctaccta cctgcggctg agccgacaat ctgcgtcgcg cctgccacgc
    11941 ccggatcgcg gttcccccat ggagggctgg tgctattggg gcaacgacga gcctgagatc
    12001 ctaatcgtga catgcggacc gatcgcggcg atggcagtag atctgcaacc tgaactggga
    12061 gcgaataccg gcgtgctgaa tatttatcgt atgaaaccat ttcccgacgc aggcttgtgg
    12121 gaaacaacac acagggcgcg ggcgatcgtg accgttgagg aacattcggt ggtcggcggg
    12181 ctcggcagta tgatgagcga gtggacggca cagcataagc cggttgtgaa tgttcccctc
    12241 ggaattgcgg atgagttcac tgtatccggt gatcactccg aactgctgaa gctgtatggc
    12301 atatcgccga ccaatatctt gaacgcggtt catttggctg tgcaccgaat ggaaaggggc
    12361 agatagcatg ttcaccgccg atagtctgct catcgaattg accgcacggg gtgtgggtga
    12421 ggtgacgggt gtgccttgct cgtatttgac gcccttgatt aatcgtgtgg catcgaacga
    12481 ccgtgtgtcc tattttcctg caacccatga gggcgaggcg gtcgcgatag cggccggtag
    12541 ttggttggct ggagctatta cttgcgtcat atctcaaaac tctggcctgg ggaatatggt
    12601 caatccccta acgtctttgt gtcatccgtg ccgaattccg gttccgatga ttgtgacatg
    12661 gcgtggcgaa ccaggtgttg ccgatgaacc gcaacatgaa ctgctcggcg caaaaacgcc
    12721 tgacttgttg acactcatcg gtgtcggcca ctcggtgctg ccctcgaagc cagagcgact
    12781 gagtgcaaca gtgggtttag gctgggaagc gatgcaacgc gatgaattgc catacgcgtt
    12841 tatactgcgt ggcgggtcga tcgctcccga ggcattgtcc gaaacctggt cgacgggtgc
    12901 ggccgaatct gtagtcatgg gtggacgtga tcggccgaga aaatgctcgc gtcgaattga
    12961 cgcactggac acgctgctga gcgctgttgt ggacagcgca gcgatagtat caaccactgg
    13021 caagaccagc cgtgaactat tcactctcgc ggataggccg cagcatttct acttggtggg
    13081 cgcaatgggc tcggccagtg cggtggggct gggcgtggcc cggcacacga gcacccccgt
    13141 cgtcgttgtc gacggcgacg gtgccagcct gatgcggatg ggcacgttcg ccacagtggg
    13201 agcggcaggg ccgccttccc tcatccacat actcctcgac aaccaggtgc acgactcgac
    13261 cggtggccag cgcacacagg ctgagtacgt caactttccg gccgtagctg cagcgtgtgg
    13321 gtaccggtgg gttttcgact gtgctgactt gttggagttc gaattcgccg tacagcgtgc
    13381 ccagaccacg caaggtcctg tttttatcta tctgcggatc aaaccaggat ccatcgagaa
    13441 tcttgggcgt cctaccgtac ggccatcaga cgtcgcccgg cgattccgag atttcgtcaa
    13501 agcgagcaag gcgggatggg ataccgctca aacgatggag gaggctcatt gcattgagca
    13561 attgtgacaa ctggcacgaa cggccggaca tcgcgtccgc cctcgcgcat ctggatgctc
    13621 actacgcgat gttggattgt aggaccccag gcgcgcgaag agaccggttt ctaaacgata
    13681 tccggcgctt ccaaaccccg atagctgaaa gcaaattacg ggcagggctc gtatcttgtg
    13741 gaacaagacg tcgctcagct gatgacatcc aaaacctcgc gttcggtact tggctgacgt
    13801 tcctagaacc ggtgcagggt ctggccgaag ccctggacga gtatcgtttt accgatgacg
    13861 gagttggttg gccaggagcc tttggccgtc agtgggcacg tcgtgccagc gatgtggcat
    13921 ggactatcta catggcgtca tgcgaaccga cctgaattcg gctgcttgcc cccggggcgc
    13981 ggagccgggc tactacggaa ccttatgaac tatgtccacg tgagatgttc ttagagactc
    14041 gcgtgtgtgc tctcctgcct cgaatccaag acaggtgcac cctagccgat tcgcatcgaa
    14101 ggaattgaag tgcgagtgta cgacagcgtg acacgtttcc cggggccgga ctatacagat
    14161 atcgcccgaa tttccgacct cgaccttcga atgatacgcg acgatacgcc ggggaccgaa
    14221 tgtgtaattc acctgaataa tgccggggca gccttgatgc ctcgaccggt gatcgatacc
    14281 atgcgggagc acatcacctt agaatcacag atcggcgcat acgaagccgc agaagcgatg
    14341 gagggtgaga tccgtgcttc ctatacctcg atagcccaac tactcggttg cagtgcgaac
    14401 gaaatcgcaa taacggacag cgcgacgcgg gcttggggcc tggcttttgg ctcgatccaa
    14461 tttcatcccg gagacaggat cctggcttcg ccggtcgagt acgggagcaa ctacctggcg
    14521 ctgctgcact cggtgcgaca cctcggtatc gaagtcgaaa tactgcgtgt cacggagtcg
    14581 agcatcatcg acactgccgc attgcgcgaa accatggacg agcgggttcg ggccattctc
    14641 gttacccatg taccaagtca ctccggagtg ataaacccga tagccgagat aggggaagta
    14701 gcgcgcaaat acggttcgct gtacatggtc gatgcctgtc agtctgtggg acaaataccg
    14761 attagcgtat ccgagatcgc ctgcgacttc ttgtccggat gtggcagaaa atatctgcga
    14821 ggcccgcgcg gaaccggctt tctctatatg cgaccagaca tctcgcacga gatcgaaccg
    14881 ccaatgttgg gattggacgg agctagatgg ttgggtggta ctcgatacga aatcgcgccc
    14941 ggcgcaaagc ggtttgaaac ctgggaggcg aatacggtgg ctaagctggg cctcggtgct
    15001 gccgtcgact attcattgac tttgggaatt cacgctattc gagaacgcgt caccacgctg
    15061 gcggactacc tacgccggtg tttgacctcg gtttcggatg tccatctgct ggaccaatat
    15121 aacgcggacg gattggccgg aatagttggt ttcgatgtcc ctgggcgaaa tctctacgag
    15181 atcagaaacc aattgaaaaa gaagagaatt aacgtttgga tttctctgtc gaataccgcg
    15241 tgcgtagaca tggagaggcg gaagctgaac gaatgcatcc gtgtatcggt gcattactac
    15301 aacacaattg aggagatcga caccttttgc aactcgctac tcgattcaat tgacgggcgc
    15361 gtgtgaagca tgactttaaa gcggatcgcg aatttcggac cggatgcgtc gcgggtattg
    15421 agctatggtt gcttgatcgc tgcggccgtg ttgttcgggt gcacgggagt cctggtcaag
    15481 aacgtcttta aaccaccata ctctacgctg tctctcatat cacttcgggc agtcgtcagc
    15541 ttgctagtaa tgttgcctat aatggtgtat aggggcctgt ctgatctgag gatagatcgg
    15601 acgcagtttc gagctctgct gggtctcggt ctgtggctgt tgctggtcaa cgtaaccttc
    15661 ttctgcgcga taaacttggt gcctgttgcc gaagtaattg ctctgcagta caccgcgcca
    15721 attgtggtgc tactcgtgga aattttgaag aaggcccagc caatgactct ttcagctggc
    15781 gccgtcgtcg tcgcctgcac cctcggtata gtactcctct cggaggtccg ctccgtcgga
    15841 ctcggaggaa agggcacagc gggtttcctt cttggtgtgg cttctggtat atccttcgcc
    15901 ttctacaatc tgcagggaaa atattctagc gcaatcggtc tcaatgcccg aacgacaacc
    15961 ttctattcga tcctcttttc tgttgttccc tgtctaccgt ttctgccctt ccttaaaatt
    16021 gactttttcg tggagagctg gcagaccttc ttctggctga tcgtggtgtc gatcctcggt
    16081 tgcggtcttc cctgcctgtt gttgttcaaa ggattgggag gggtcagcgc ctttccggcg
    16141 acggtcgtag gtgttctgga gcccgttgtt gcggcgattt gtgcatatgt ggttctgcat
    16201 gagaacctgt cgctgcaaca aatggctggg ggagtagtcg ttgtttgtgc agcggtttac
    16261 gctccgaggt cggtttctcg gagatatcgc tgaggcggta tttctcatat cccttcgacg
    16321 tttggaagac ttgatttgat tattgaacac catccggcag agcttctcga cacatatctg
    16381 gagatctgtt cgggagagca gctgttcgta tcccaggcac tcgcggcttt cgatgcggta
    16441 gattcgcttg gcagtatgct cgactgtgca gtcggtaccg gattcgggac gatcccgttg
    16501 ttgcggtctg gtctaccgct cgtttgctca gatggcagcg ccgagatgat agaaagattt
    16561 cacctgaact gcagacgtgc ggggctggga aaccggtcga ttctggccca atgggcagac
    16621 ctgccgaact actttccggc cgtcttcgac ctggtaatgt gccgggggaa ttcattggcg
    16681 tacgccgact cgtgggacga cgaggaagct cccaaccccg atccggaaag aatcggtcgg
    16741 cacctgcgcg gtatggcggg agcgctgcgc agcggcggtg cgttgctgtt ggacatcccg
    16801 gatacccgtg acatcacatc agatgtctcc tatgtcacgg agaacggcgg gttaaccagg
    16861 gatggtctgc gtgtggcgat tgtcgacgaa gtgcacgtat cactggcgca ccgtctcaga
    16921 cgatggcgca cgacaatgac gatcgacggg acggtatatg ggttcgaaag aacgtcgcat
    16981 ctgattcaat tggaggaagt tcggtccgac ttaaaggcgt gcggcttcga cgaagtgaaa
    17041 acacttgaga tcaggaatat tcgagataat ttcatttcac tcttggcgat aaagttgtag
    17101 ttctgttgtc tcaatggaaa gtagtcggcc cgtatgcgga tagtagtagt ttgcggtgga
    17161 gtaagttccg aacgaagtgt ctcgatgtct tctggtctga ctgtaacgaa agctctaatc
    17221 gccgcgcatc acgacgttgt cgtgctcgat ccggcacagc agccgtcggt gctcatcggc
    17281 ggttccggct cgggtacaga ccacctcttc gacctggaga tccaggctga actgcctggt
    17341 tccggcgtcg gtcggtgcgg agcctcattt ctcgactcgc tgatggcacc cgatgtgtgg
    17401 gatcagctca gaggcgcgga catcgtcttc gtcgccctgc atggcggatg gggcgaggac
    17461 gggcatgtgc aggcactgtt cgagatggcc ggtatccctt tcacgggcgc gagtagcgtg
    17521 gcatgcaatt tctcgtaccg gaaaagtcga agtcttcagc tgttaaaagc agccggagta
    17581 ccgacacctg agcacgttgt gtgggaaagc caggtacggt cggtgcctgc cgatgctatc
    17641 gcgatggtaa atcggggacc tgtcgtcgtc aaacctgata ctgaaggctc aagtgtaggc
    17701 gctcatttgg tcgataatgc agtacagatc gaatcgatca agaacaatac cgctgatctg
    17761 gtaatcggtc cctacctccc gggccgggag ttcacagtcg gcgtcatcgg cgatacggtg
    17821 ctgccaccgg tcgagatcaa caatattcgc gccttgttcg attaccagtc caagtatcga
    17881 agggaagttt cctgtcaatg ccccgcccct gtcgatgatg cattgaacga gcgtctgaaa
    17941 aagtatgctc tcagtgcaca ccaagcgctc gccttcgact cgacgatgta ttcgagaata
    18001 gatttccggt gcgacgcgga cgaaaatcca tttgtgctag aggtgaatgc acttcctggc
    18061 ctctcgccgg tgagtttgtt gcctctggcg gccatgcagc tgggctggag ctatctggag
    18121 ttgatcgaat ccttgatcaa cctgaagctt agtagtattc ggagatgtcg gtccgtttca
    18181 gcatccagcg gttaatattg caactggtac gctcagagat gaaatgatgg ccaggttagt
    18241 gaccgatcgg aagctggtcg tcgcgagcca gtgtgagtcc ggtccaggta actgcgaacg
    18301 gacgtcgtcc cgggtgcgtg ctcgtacgag aagtgctgga ggaactcaaa tccgcccgcc
    18361 gcctccggac cgtgatccgg caggtaccga aagatcatcc gagtccccgc ctggaaccca
    18421 caccgcccca ggcgccctca atcaacgaag aaaccaaccg acaaggcccg gttcgtacat
    18481 cccttcgcag atggccccta ccgctacgtc aacggcatgg ccattatcta gccagagcgc
    18541 ctgttcaaac tgttctgtgc ccgggataga cgggctgctg cagggggtgt cattgtcatc
    18601 cgcggcgcat ggcgtgttgg acgtggtcgc ggtcaggggt gatctgggcg tggcgctggg
    18661 tcatggcggg gatggggatc gtcccggtta tgtgggcttg gtagacggcg cgggcgtctt
    18721 cgaaggcgtc gcgggcgccg aaccgtcgaa ttcggcctcg gaagaatcac atacgagacc
    18781 aatctgaccg ccgacaacgg gcgagaactc cgcaacactg tcgcctactg ggcccagcac
    18841 gcgcgaaaga tctctgcata caacagattc cgccgctagg gtctgatttc ttctctcgca
    18901 gcgagatgga ccacaccagc tgaccgaaga acgcgcaccc gaagcgcctc caccggtaaa
    18961 gcgatctcgg gtcgtcggaa gtgttcgacg gagtgggcaa ctggcctcgg ccgggtcaac
    19021 ttgcggtgta gcattatcgt gtgcggcccc cgaactaccc cttggttcgg gggccgatac
    19081 ccatacgtcg attgccgaac tcggagggtg gatagttcgt tatttctgtc ccggcgcggg
    19141 tgtaatcggc ggcgggggag tctgtacgaa cggttcgggg gcgaacttgt cgcagtgcac
    19201 gctgggggat tcgttgggag ctccgggtgg ttcgattgcg gtgacgagtg tgcgtggggc
    19261 gggtgtctga tatgggtctg cggccgaggg ttttgttgtc gacactacgg tcagcgcttc
    19321 agcggcgtgg gaacgattcc cggggtcttt gaccagcttg tcgtcgataa ggctgtatgt
    19381 gccgggtgtg tcgaactggc acagggtcac gcggtagccg tcctcggcag gcgtggtgcc
    19441 gactactctc cagagcattc caccggtggc tggccacttg ctttgtgtcg cctcccagct
    19501 cgatctggaa ccgatgtatg tacgagtgac acgttcgttg taggcacgtt cgaggtcggg
    19561 ttcgtagtgg tcggcccaca tgaattgatc atctgccatt gcggtttcgg cggcgaatcg
    19621 tgcggcagct tcttcttggc ccgtcagcgg taccgcgaaa tcccaagtga aggtaacggg
    19681 cggatagggc gacttcggcc gagctgtcgt cgttggtgct gatggtgatg cggtgggctg
    19741 gccgggctgg ttcgcgcagg cggtgaccac cgcggcggtg gcgcagagaa cggccgatgc
    19801 tctgatgatc gtgcggttgc tgtaaagtga cgttcctgtc atttcatctc cagcttttcg
    19861 gatcctccat caaggaagtt ctggagcttt tgccgatcgt ccttcaggcc catcgcaatg
    19921 gcgatgtcgc cggactgttc cgactcacgc atatagtctg tcaaacctcg atcgtgcaag
    19981 taccgcgtca gcgcatcgct cgtgcctttc gggttttggt ccgctacatg gatcggtccg
    20041 ttgtgatcgg cgttgagcag gtccgagggt agctgaccgt ttcgataggc tgcgtccagt
    20101 agcttgttcc tcgtttcgtg acttaactcc gcggaaatgt tgttgacgtt cggatcttgg
    20161 acatggatcg gatcgggctt ggggttccag gcttcgatcg cggagtccat ccattttgca
    20221 ggcaggccgg tgccatactt gttgacggga tcaccgacta cgctgggaag aaggtcggtg
    20281 gccggtttgg tgattttgtc catgggaact gcgttggtga ccagctcttt tgcgatgtcc
    20341 gcagctttct gtttgctgtc gtagac
//
