LOCUS       NZ_KV411303            21401 bp    DNA     linear   CON 12-FEB-2024
DEFINITION  Nocardia terpenica strain IFM 0406 scaffold1, whole genome shotgun
            sequence.
ACCESSION   NZ_KV411303
VERSION     NZ_KV411303.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardia terpenica
  ORGANISM  Nocardia terpenica
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 4641778)
  AUTHORS   Buchmann,A., Eitel,M., Koch,P., Schwarz,P.N., Stegmann,E.,
            Wohlleben,W., Wolanski,M., Krawiec,M., Zakrzewska-Czerwinska,J.,
            Mendez,C., Botas,A., Moris,F., Cortes,J. and Gross,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-APR-2016) Pharmaceutical Biology, University of
            Tuebingen, Auf der Morgenstelle 8, Tuebingen 72076, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 30-JUL-2014
            Assembly Method                   :: CLC NGS Cell v. 7.0.4
            Genome Coverage                   :: 118.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/12/2024 01:56:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,832
            CDSs (total)                      :: 8,760
            Genes (coding)                    :: 8,562
            CDSs (with protein)               :: 8,562
            Genes (RNA)                       :: 72
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 40 of 198
            Pseudo Genes (incomplete)         :: 174 of 198
            Pseudo Genes (internal stop)      :: 9 of 198
            Pseudo Genes (multiple problems)  :: 23 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:51:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2099000
            Orig. end                         :: 2120401
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KV411303.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21401
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="9"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21401
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21401
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11401](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11401
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(112..1605)
                     /locus_tag="AWN90_RS09595"
                     /old_locus_tag="AWN90_09635"
     CDS             complement(112..1605)
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011206612.1"
                     /locus_tag="AWN90_RS09595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_09635"
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="WP_067579561.1"
                     /transl_table=11
                     /translation="MSAPAPPSAGAFLSPPGGFAPAPAPSTRRNAELLLLAFAVIITMA
                     ALVLVEASQDRQAWWQLARLGLAYLALFAVAHLAVRRFATFADPLLLPIAALLNGLSLV
                     LIHRLDLAEAQTAADNSLPMPAPDAGAQVLWTALGIAVFFALLVLLRDYRTLARHGYPL
                     GLLGLVALLVPALLPPKYAELDDAKIWIRVPGFSVQPGEFAKVLLVVCFAAVLVSKRDL
                     FTAAGRHLVGMELPRTRDLGPLAVVWLVCLGVLVFEQDLGASLLIFATALAMLYIATER
                     IGWPVVGGALLVVGFAFAYNAFGQVRVLVSTWLHPFDDYHSTGYQIAQSLFGLATGGLA
                     GTGLGSGRPSQVPFAKTDFIIATVGEELGLIGLTVVLLLFAMLIVRGLRTALAVRDSFG
                     KLLAAGLAAILAVQVFLVVGGVGKLIPATSLTTPFVSYGSSALLANYALLALLVKISDA
                     ARAPAPTRKKEQTPIADAPTELLRPDKTEILRPAKGETI"
     misc_feature    complement(1411..1413)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(1605..3062)
                     /locus_tag="AWN90_RS09600"
                     /old_locus_tag="AWN90_09640"
     CDS             complement(1605..3062)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019931983.1"
                     /locus_tag="AWN90_RS09600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_09640"
                     /product="PP2C family serine/threonine-protein phosphatase"
                     /protein_id="WP_067579563.1"
                     /transl_table=11
                     /translation="MTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEV
                     ASQLMIAALAHLDDDEPGDDLLGKLDRAVHEGNAAIADQVEEEPELDGMGTTLTAILFA
                     GKKLGLAHIGDSRAYLLRGGELAQITRDDTFVQSLVDEGRITPEQAHTHPQRSLIMRAL
                     TGNEIDPTLTMREARAGDRYLLCSDGLSDVVSDETIANTLREGGTDEAADRLIELALRS
                     GGPDNVTVVVADVIDLDYGQSHPIVAGAASGEDEDTPPPNTAAGRAAAMRPPRATPRRA
                     AVQPDPPEPRKSHKLRWSLLALALVVAVGVGLVVGYKMIRSNYYVGADNGNVVILRGLP
                     GSVLGYSIRDVDQLACVDRDGRLTLTRPGAEFPSGCKQLQVSDLKQTGRDKVNNGLPPG
                     GFDDAHRQLETLARQELLPACPKPVAPPVVPPIPPAPPADGSAAGSSASAPNPSATNNP
                     AHSESQVPPTTPAPAPQTPGENCRKAD"
     gene            complement(3059..3526)
                     /locus_tag="AWN90_RS09605"
                     /old_locus_tag="AWN90_09645"
     CDS             complement(3059..3526)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005064443.1"
                     /locus_tag="AWN90_RS09605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_09645"
                     /product="FHA domain-containing protein"
                     /protein_id="WP_067579565.1"
                     /transl_table=11
                     /translation="MQGLILQLTRAGFLLLLWLFVWAVLRTLRSDIYAASGIRIQPRAA
                     RGSAVLPSFSRGQKGAKYLVVTQGSLAGTRITLGTQPVLIGRADDSTLVLTDDYASTRH
                     ARLSPRGEDWYVEDLGSTNGTYLDRAKVTTPVRVPLGTPVRVGKTVIELRS"
     gene            complement(3712..5082)
                     /locus_tag="AWN90_RS09610"
                     /old_locus_tag="AWN90_09650"
     CDS             complement(3712..5082)
                     /GO_function="GO:0051219 - phosphoprotein binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019665029.1"
                     /locus_tag="AWN90_RS09610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_09650"
                     /product="DUF3662 and FHA domain-containing protein"
                     /protein_id="WP_067584784.1"
                     /transl_table=11
                     /translation="MGIVSRFERRLQGAVGDAFARVFGGSVVPQEVEAALQREAAGQVG
                     ELEGGHLLAPNSYTITINPSDLQQLDADHELTTRAFARHLQDYIHAQGWQTYGEVHVEF
                     EASPTLHTGQFRTSGRVDPDVGRRNPPAPPRPNDRPGPPPHRTAHPQPGAGPMTQNSGY
                     DPSREPAESDPRNRGYAPPPGGRPGQQNYRDDYGRGGQYPGAAEYAAPESQQAYGDYQN
                     GYDYQQQGHGYGQAPGYGQQGGYEQGYAEQGYGQQGYEHQGYGQQQGYADQGYGHQGYA
                     EQGYADQGYGQQQSYGQAPAYDQGYGQQPGYGQQGYDQGYGEQGGYGAEDPGYGQGYGQ
                     QQGYAQQGGYAAAPQAPHSGSGYSATLQLDDGSGRTYQLREGSNIIGRGQDAHFRLPDT
                     GVSRRHIEVRWDGQVAMLSDLGSTNGTLVNGSPVQDWQLADGDVIRAGHSEILIRIV"
     tRNA            5322..5407
                     /anticodon=(pos:2104355..2104357,aa:Leu,seq:cag)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="AWN90_RS09615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="AWN90_09655"
                     /product="tRNA-Leu"
     gene            5322..5407
                     /locus_tag="AWN90_RS09615"
                     /old_locus_tag="AWN90_09655"
     misc_feature    complement(5496..5512)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 19.52"
                     /tool="antismash"
     misc_feature    5501..5514
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.14"
                     /tool="antismash"
     gene            5571..5999
                     /locus_tag="AWN90_RS09620"
                     /old_locus_tag="AWN90_09660"
     CDS             5571..5999
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS09620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AWN90_09660"
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="WP_156673981.1"
                     /transl_table=11
                     /translation="MITPIVPPQAPLQELIHGPIAYPVPVRGTSDDLVYGMSTVGEAGR
                     ILDRQVFRKLGWRPGKRLNIRCPEHGVLLVAPARDGAAIVTPDEFFRVHYKLRRRVNLF
                     IGDRVLLIGRVSRSRLVVHPPAAMDELFAESVRLLDRW"
     gene            complement(6358..6522)
                     /locus_tag="AWN90_RS45225"
     CDS             complement(6358..6522)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS45225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_156673982.1"
                     /transl_table=11
                     /translation="MRRGEPIVRAAAAVLALAAAGLGFGFAVVAAAPVSSAQGYMSDDR
                     IQPLSSAKR"
     gene            complement(6522..6833)
                     /locus_tag="AWN90_RS09625"
                     /old_locus_tag="AWN90_09665"
     CDS             complement(6522..6833)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS09625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AWN90_09665"
                     /product="hypothetical protein"
                     /protein_id="WP_067579566.1"
                     /transl_table=11
                     /translation="MTSTNPGVDATGKQPRHGADNTTPRTASQADADIAALAIPAIVLG
                     VAMLIAAFAGMDRIPGWADEIGAVLVYLAFFLYMSVAGRLTWWGSDTLIAQIRRKRGR"
     gene            complement(6887..7534)
                     /locus_tag="AWN90_RS09630"
                     /old_locus_tag="AWN90_09670"
     CDS             complement(6887..7534)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014983797.1"
                     /locus_tag="AWN90_RS09630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_09670"
                     /product="MspA family porin"
                     /protein_id="WP_231951363.1"
                     /transl_table=11
                     /translation="MSFSGSATACAGVLVATMVAAVWAGGSADADITADKRRDIGTDDG
                     WTLSVTKTQESLDRWPALDATPTSREGFASLEATADITGNGTKPVNSATVTLGYQVGCQ
                     IDVSTGLTLGMGLSFGPNVSVNISYPPSVSVGAQASVTPNIQTTVKPGTIATIPFGSKP
                     LAASHASITADQVEVKVDACLGPVTLRSFATAAMSTATADNSVTVYGDPITL"
     misc_feature    complement(7885..7900)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.61"
                     /tool="antismash"
     misc_feature    8283..8298
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.69"
                     /tool="antismash"
     gene            8438..9832
                     /locus_tag="AWN90_RS09635"
                     /old_locus_tag="AWN90_09675"
                     /pseudo=""
     CDS             8438..9832
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040250.3"
                     /locus_tag="AWN90_RS09635"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_09675"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPVQTDNQQRKSLSTGAAHQLAHTTKSEPQMQGITSRWLTRMLPW
                     TQVGGGVYRVNRRLTHTVGNGEVEFVVDGSQARVIPLELTELPQLRDFDDEEVLAALAH
                     RFEQRDLDPGVVVAEFGNPMDQVMLIVHGKLAKLGTGEYGEQTRLGLLGDGDFFGDATL
                     TDADAIWPVTVRTMTRTTMLVLRRESLLQMLEQAPALGEQLSRVAAEPARPQNTKGEAD
                     IQIQSGHAGEPLLEGTFVDLDASPREYELSLAQSVLRVHTRVADLFNDPMNQVEQQLRL
                     TIEALYERREHDLVNNPDFGLLHNCDLKQRIYSESGAPTPDDMDDLLSMRRSTKLFLAH
                     PKAIAAFGRECSKRGLYPDPVEVDGHRCFAWRGVPIFPCSKIPVSDTQTTSILAMRTGE
                     KDQGVIGLH"
     misc_feature    complement(8442..8457)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.73"
                     /tool="antismash"
     misc_feature    8990..8992
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10001..11401
                     /locus_tag="AWN90_RS09640"
                     /old_locus_tag="AWN90_09680"
     CDS             10001..11401
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041167.1"
                     /locus_tag="AWN90_RS09640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_09680"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_231951364.1"
                     /sec_met_domain="T1TS (E-value: 3.1e-61, bitscore: 206.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRHLLGPRGLGAAALRLPLPELDLTPAEVLPADAPAQEDIPAAV
                     PGRAVIPLGPTGLGSAAGYFHRVTAEPPSVEPLGPAEPVAGTLNPPAVPHPAESVDEIR
                     PASVHRIPTAPTGLGAASALLRPRSTPAGTTESTVRSSVIPPLYCPPPVRDNPELAELV
                     NDGLIAWAAEIGLYEGRLDELRDADFGRLIMLAHPDSDDPDRLLAVAKCAVTEWSVDDY
                     YCEEDAPDTAPDGSPSQAWAELGPKLEMAAAAMDPVHLPARYAPQLEEALQADPILRAF
                     RTSFEHFARYGTPTQVARLRTEIAGWFIALAAEAGWRAAGRMPPVWEYLTNRQPHSFLP
                     CMAPLDAVGGYELPAAEYADPRVRRLVTTAALASQMVNDLYSMAREDLSGGREFNLPTV
                     LAAEEGCSRHDAVQRTAEVHDELVHRFEREATVLAATGTPELRRFLGGLWAWLGGNRAW
                     HAESKRYR"
     misc_feature    10550..10552
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11510..12382
                     /locus_tag="AWN90_RS09645"
                     /old_locus_tag="AWN90_09685"
     CDS             11510..12382
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014984011.1"
                     /locus_tag="AWN90_RS09645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_09685"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_067579568.1"
                     /transl_table=11
                     /translation="MSTEETGTGPVLRTSYQRSVAAYWNNNPNDDRVNTELGEVDGLYH
                     HHYGIGEPDLSVLEAPQAVRQQRIIEELHRLETAQAALLLDHLGKVGPGDRLMDGGSGR
                     GGTSFMANQRFGCRVDGVTISEYQVGFANEQAEQRKVTDQVAFHFRNMLDTGFDTGCMR
                     GIWTNETTMYVDLFDLFREFSRLLQPGGRYVCITGCSNDVNGGRSSSVSGIDAHYGCMI
                     HPRSEYFRALAENNLVPIDVVDLTAATIPYWELRTKSELATGVEKAFLTAYREGSFQYL
                     LISADRVRR"
     gene            12515..13312
                     /locus_tag="AWN90_RS09650"
                     /old_locus_tag="AWN90_09690"
     CDS             12515..13312
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019929642.1"
                     /locus_tag="AWN90_RS09650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_09690"
                     /product="DUF4239 domain-containing protein"
                     /protein_id="WP_067584796.1"
                     /transl_table=11
                     /translation="MFTWVYEMPSWLSFLVITGVFVAITCSGVIIARPGVRKIFARQPG
                     MNEMVTMVLTVGGVFYGLLLGLTAAATYQSFDSANTIVADEAATLGVLYREVSAYPEPE
                     RGVLQKDLVDYTDNAINVAWPALRKGEESTIGTALVTRFQQHLLAFHPQTESDKIVHAA
                     AIEQFAHFIQVRLHRLADSSGGIPNLMWTVIVIGAAVNIALMCLFTLEHRTAHLVLAGL
                     FAFFLATMIYLIAAMDYPFRGDLSISPEPFITTYIIVMGQTSH"
     gene            13367..14350
                     /locus_tag="AWN90_RS09655"
                     /old_locus_tag="AWN90_09695"
     CDS             13367..14350
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019925299.1"
                     /locus_tag="AWN90_RS09655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_09695"
                     /product="delta-60 repeat domain-containing protein"
                     /protein_id="WP_067579570.1"
                     /transl_table=11
                     /translation="MSSKTPYRAATLLQRAVLVAAIGAAACACSGSHDSAAAGSLDAGF
                     GSGGKVTTDLGSSADRANTVTIQTDGRIIVAGSTQDPAQGDNFAVVRYITDGQLDPSFG
                     DGGKVSTDFGSESDIANAVVIQPDGKIVAVGTSHGTASGDDIALARYAVDGKLDASFGN
                     GGKVRTDLGSKADHANAAAIQSDGRIIVAGSTQDPARGDNFAVARYTTDGKLDPSFGDG
                     GKVSTDFGGESDIANAVVIQPDGKIVVVGTSHGTDTGDDIALARYTTDGKPDISFGNDG
                     KVSTDLGSKADHANAAAIQSDGRIIVAGSTQDPTQGDNIAILRYHG"
     gene            14830..15417
                     /locus_tag="AWN90_RS09660"
                     /old_locus_tag="AWN90_09700"
     CDS             14830..15417
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS09660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AWN90_09700"
                     /product="hypothetical protein"
                     /protein_id="WP_067579572.1"
                     /transl_table=11
                     /translation="MVILLRGIRGFSRLLIIAAAAALSAPALIGSGVVRAETEAERQQA
                     AAQSVFENLLCKEGNGKNGLEPHTDDWYHDWMKIEDSAPYEMKGNGSPGKSARKTLYKV
                     ANLNPETRKEICENTTRYANELEAQTDHLKGDLKLTCRVNIDRRIDKDGELGKTLNCGD
                     SAGQAKLVDTKFLAYKKITDYDDEGNYGGPKK"
     misc_feature    complement(15935..15949)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     misc_feature    complement(15954..15966)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            16009..16152
                     /locus_tag="AWN90_RS45230"
     CDS             16009..16152
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS45230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_156673983.1"
                     /transl_table=11
                     /translation="MHGADTGDDIALARYTTDGKPDTSFGNDGKTSTDLGSKADHANAA
                     AI"
     gene            complement(16386..16556)
                     /locus_tag="AWN90_RS45235"
     CDS             complement(16386..16556)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS45235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_156673984.1"
                     /transl_table=11
                     /translation="MSAATAARDATDRACTSAARSTLTSTNTLAVAAEHRYGADRLAAL
                     ADTAERLVPGL"
     gene            16897..17415
                     /locus_tag="AWN90_RS09665"
                     /old_locus_tag="AWN90_09705"
     CDS             16897..17415
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS09665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AWN90_09705"
                     /product="hypothetical protein"
                     /protein_id="WP_156673985.1"
                     /transl_table=11
                     /translation="MSVRVRGIGSVVAVAAVMLCAGIGSAGSASAEPPWGTHCKGAKAE
                     AKKEKPFIIQACQRAYSAKARAIIADDATKTDATTKADAAADAHTADDATDAAFEAAQL
                     AAKAATSSKVTADAAVDAAEAARAARDEPMDVALANKAAEAEEKAVAASRKAFGGPGQV
                     KIPRLTSAG"
     gene            complement(18670..19305)
                     /locus_tag="AWN90_RS09670"
                     /old_locus_tag="AWN90_09710"
     CDS             complement(18670..19305)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014982263.1"
                     /locus_tag="AWN90_RS09670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_09710"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_067579576.1"
                     /transl_table=11
                     /translation="MTETDGRKLRGNRTRASVLDAVVSLASVEGLDGLSLSQLAARLDV
                     TKSALFTHWRGKEELQLAALEHASTQWVTEIIAPALEQPTPLQRLWALHERRLDFYARE
                     MLPGRCFFSIVYREFDDRPGVIHDRLIEQSAQWHAFLTATIDEAIEAGQLCEHTDSDQL
                     AYEIDSLGEGVVSRVRMLDPQFALAAARAAVLQRLRAASVDPDTLPES"
     misc_feature    complement(19583..19598)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.41"
                     /tool="antismash"
     gene            complement(20028..20216)
                     /locus_tag="AWN90_RS46930"
                     /old_locus_tag="AWN90_09715"
     CDS             complement(20028..20216)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS46930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AWN90_09715"
                     /product="hypothetical protein"
                     /protein_id="WP_067579578.1"
                     /transl_table=11
                     /translation="MNNCFSIAENEHSKDEQLYAFKVRNTPTLSPMYTTTDSDAMKAKP
                     ISTHTAWSSRQASMSGM"
     misc_feature    20435..20451
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.91"
                     /tool="antismash"
     gene            20936..21103
                     /locus_tag="AWN90_RS45240"
     CDS             20936..21103
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS45240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_156673986.1"
                     /transl_table=11
                     /translation="MIDGRAGASMPVRCLALRLFDIESFESRGEFMLLGVLSALLTGLS
                     NVVAALLSGA"
ORIGIN
        1 gcgggtcgtt gcgcaggctg tcggccttga tgacctgaac gtaggtggcg ttcaacagca
       61 gcgcgacgat catgagcatc acggccatcg ccacgcgacg caggggcgta ttcatatcgt
      121 ttcccctttc gccgggcgga gtatttccgt cttgtccggg cggagcagtt ccgtcggggc
      181 gtcagcgatg ggtgtctgct ccttcttccg ggtcggtgcc ggcgcacggg cggcgtcgga
      241 gatcttcacc agcagcgcga gcagcgcgta gttcgccagg agcgcggaac tgccgtagga
      301 cacgaacggg gtggtcaggc tcgtcgccgg aatcagcttg ccgacgccgc cgaccaccag
      361 aaacacctga accgccagga tggccgccaa tccggccgcg agcaacttgc cgaagctgtc
      421 gcgcaccgcc agcgcggtcc gcaggccgcg cacgatcagc atggcgaaca gcagcagcac
      481 cacggtgagc ccgatcagcc cgagttcctc gccgacggtg gcgatgatga aatcggtctt
      541 ggcgaagggc acctgcgagg gccgcccgct gcccagcccg gtaccggcca gcccgccggt
      601 ggccagcccg aacagcgact gcgcgatctg ataaccggtg ctgtggtagt cgtcgaacgg
      661 atgcagccag gtcgacacca gcacccgcac ctgcccgaag gcgttgtagg cgaacgcgaa
      721 tccgaccacc agcagggcgc cgcccacgac cggccagccg atccgctcgg tcgcgatgta
      781 cagcatcgcc agcgccgtcg cgaagatcag cagcgaggcg ccgagatcct gctcgaacac
      841 cagcaccccg aggcacacca gccacacgac cgcgagcggg cccaggtcgc gcgtccgcgg
      901 cagctccatg ccgaccaggt gccgcccggc ggcggtgaac aggtcgcgct tggacaccag
      961 caccgccgcg aagcacacca ccagcaggac cttcgcgaat tcgcccggct gcacgctgaa
     1021 tccgggcacc cggatccaga tcttcgcgtc gtcgagctcc gcgtacttcg gcggcagcag
     1081 cgccgggacc agcagtgcga ccagtccgag caggcccagc gggtagccgt ggcgggccag
     1141 cgtccggtag tcgcgcagca gcaccagcag cgcgaagaac accgcgatgc cgagcgcggt
     1201 ccacagcacc tgggcgccgg cgtccggggc gggcatcggc agggagttgt cggccgcggt
     1261 ctgcgcctcg gccaggtcca ggcggtggat cagcaccagg ctcaacccgt tgagcagcgc
     1321 cgcgatcggc agcagcagcg ggtcggcgaa cgtggcgaag cgccgcaccg ccagatgcgc
     1381 gaccgcgaac agcgccaggt acgccagccc taatcgggcc agctgccacc acgcctgccg
     1441 atcctggctc gcctcgacca gcaccagcgc cgccatcgtg atgatcaccg cgaacgccag
     1501 cagcagcagt tcggcattgc gccgggtcga cggcgccggg gcgggagcga acccgcccgg
     1561 cggactgagg aacgcccccg cggacggtgg tgccggtgcg gacatcagtc cgccttcctg
     1621 cagttctccc ccggggtttg cggggccggc gcaggggtcg tcggcggaac ctgcgactcg
     1681 gaatgagccg gattgttggt cgcgctggga ttcggggcgg acgcgctgga ccccgcggcg
     1741 gaaccgtccg ccgggggcgc cggtgggatc ggcggaacga ccggcggcgc aacgggtttc
     1801 gggcaggccg ggagcagttc ctggcgcgcc agggtctcca gctggcggtg cgcgtcgtcg
     1861 aaaccgcccg gcggcaggcc gttgttgacc ttgtcgcggc cggtctgctt gagatcggag
     1921 acctgcagtt gcttacagcc ggaggggaat tcggcgccgg ggcgggtcag ggtgagccga
     1981 ccgtcgcggt cgacgcaggc gagctgatcg acgtcgcgga tcgagtagcc cagcaccgag
     2041 ccgggcagcc cgcgcaggat caccacattg ccgttgtcgg cgcccacgta gtaattgctg
     2101 cgaatcatct tgtagcccac cacgagcccg acgccgaccg ccacgaccag cgccagcgcg
     2161 agcaggctcc agcgcagctt gtggctcttg cggggttcgg gcgggtccgg ctgcacggcg
     2221 gcgcggcgcg gcgtcgcgcg cggcgggcgc atggccgcgg cccgcccggc ggcggtgttc
     2281 ggcggcgggg tgtcctcgtc ctcaccggag gcggccccgg ccacgatggg atggctctgg
     2341 ccgtagtcca ggtcgatgac gtcggcgacc acgacggtca cattgtcggg accgccgctg
     2401 cgcagcgcca attcgatgag ccggtcggcg gcttcgtcgg tgccgccctc gcgcagtgtg
     2461 ttcgcgatgg tctcgtcgct gaccacatcg gacaggccgt cggagcacag caggtaccga
     2521 tcgcccgcgc gggcctcgcg catggtgagg gtcgggtcga tctcgttgcc ggtcagcgcg
     2581 cgcatgatca gcgagcgctg cggatgggtg tgcgcctgct cgggggtgat gcggccctcg
     2641 tccaccagtg actgcacgaa cgtgtcgtcg cgggtgatct gggcgagctc gccgccgcgc
     2701 agcagatagg cgcgggagtc gccgatgtgg gcgaggccga gtttcttgcc cgcgaacagg
     2761 attgcggtga gcgtggtgcc catcccgtcg agttcgggct cctcctcgac ctgatcggcg
     2821 atggcggcat tgccctcgtg caccgcgcgg tcgagcttgc cgagcagatc gtcgcccggt
     2881 tcgtcgtcgt cgaggtgggc cagcgcggcg atcatcaact gggaggcgac ctcaccggcg
     2941 gcgtgaccgc ccatgccgtc ggccagcgcg agcaggcgcg caccggcata gacggagtcc
     3001 tcgttgttcg cccggacgag accgcggtcg ctacgcgctg cgtagcggag aacaagtgtc
     3061 acgatcgcag ctcgatcact gtcttgccga cacggacagg ggtaccgagt ggaactcgga
     3121 ccggggtggt gaccttcgct cgatcgagat aggtcccgtt ggtggagccc agatcttcga
     3181 cgtaccagtc ctcgccgcgt ggggacagcc gcgcgtgcct ggtcgaggcg tagtcgtcgg
     3241 tcaacaccag ggtggagtcg tcggctcgcc cgatgagcac cggctgggtg ccgagcgtga
     3301 tccgagtgcc ggcgagtgaa ccttgagtca ccactagata tttggcgccc ttctggccac
     3361 ggctgaagga tggcagcacc gcggaaccgc gcgcggcccg gggctggatc cggatgccgg
     3421 atgccgcgta gatgtcgctg cgcagggtgc ggagcaccgc ccacacgaac agccacaaca
     3481 gcaataggaa ccccgcacgg gtcaattgca ggatcagtcc ctgcacggcg ttccacctcc
     3541 tgttcgaccg gtgccgtagg tgcggttcga cccccaaccg gcgtgctggt cagcacgacc
     3601 cggctgccga gcgagtattg gcagcatcat agggccgagg accggttgcg agcacgatac
     3661 ggccgacgaa ttcgaggccg catcgtgacc tgcaccggcg agcttacggg atcagacgat
     3721 ccggatcagg atctcggaat gtccggcgcg gatcacatca ccgtcggcga gctgccaatc
     3781 ctgcaccgga gagccgttga ccagcgtgcc gttggtcgac ccgaggtccg acagcatcgc
     3841 gacctgcccg tcccaccgca cctcgatatg gcggcgggac acacccgtgt cgggtaggcg
     3901 gaagtgcgcg tcctggccgc ggccgatgat gttgctgccc tcgcgaagct gataggtgcg
     3961 accgctgccg tcgtcgagtt gcagggtcgc ggaatagccc gaaccgctgt gcggggcctg
     4021 cggcgcggcg gcgtacccgc cctgctgggc gtagccctgc tgctgcccgt acccctggcc
     4081 gtagccggga tcctcggcgc cgtagccgcc ctgctcgccg tagccctggt cgtagccctg
     4141 ctggccgtac ccgggctgct ggccgtagcc ctggtcgtag gcgggcgcct ggccgtagct
     4201 ctgctgctgc ccgtagccct ggtcggcgta accctgctcg gcgtagccct ggtggccgta
     4261 accctggtcg gcgtagccct gctgctggcc gtagccctga tgctcgtagc cctgctggcc
     4321 gtaaccctgt tcggcgtaac cctgctcgta cccgccctgc tggccgtagc cgggcgcctg
     4381 cccgtacccg tggccctgct gctggtagtc gtagccgttc tgataatcgc cgtacgcctg
     4441 ctgcgactcc ggggcggcgt attcggcggc accgggatac tgcccgccgc gtccgtagtc
     4501 gtctcggtag ttctgctggc cggggcggcc tccgggcgga ggtgcgtacc cgcggttgcg
     4561 tggatcggac tccgcgggct ctcggctggg gtcgtagcct gagttctgcg tcatggggcc
     4621 agctcctggt tgcgggtgtg cggttcggtg tgggggaggt ccaggtcggt cgttcgggcg
     4681 gggaggcgcc ggcgggttcc ggcggcccac gtcggggtcc actcgaccac tcgtcctgaa
     4741 ctgcccggtg tgcagcgtag gtgatgcctc gaactcgaca tgcacttcgc cgtaggtctg
     4801 ccacccctgt gcgtggatgt agtcctggag gtgccgggcg aacgcgcggg tggtgagctc
     4861 gtggtcggcg tcgagttgtt gcaggtccga cgggttgatg gtgatggtgt aactgttggg
     4921 ggccaacaga tgtccgccct cgagctcgcc gacctggccg gcggcctcgc gctgcagtgc
     4981 cgcttccacc tcctggggca cgacgctacc gccgaacacc cgggcgaagg catcaccgac
     5041 ggcgccctgt aggcggcgct cgaagcgcga cacgatcccc acctcggcct cccttcggcg
     5101 cgcgtacgtc ggcattgtcg gtctactgtc accattccgc gacacgccga atgggcgtgt
     5161 cgtcggacgg acacggtctt tgcatgatat ccacgatcgt ccacacctgt aactcttggc
     5221 aggccgcacg ggttcccgag cctcgacacg atgatggaaa cccctgtgaa caggcgattt
     5281 cgtgactgca tcggccgcat gatacggtct tcgagtcgct cgggcgagtg gcggaatggc
     5341 agacgcgctg gcttcaggtg ccagtgtcct tcgggacgtg ggggttcaag tcccccttcg
     5401 cccaccagaa cgacggcata cgtgccacat ccgacgaagt agtgttcaag tgcgcttgaa
     5461 cactcggagg tggcaagcga aatgtatgtt gtcgcacgtc atttgatgac aaatccgccg
     5521 atcatcccag ccgggacggt cggcgttttg cgttctcagg ggtggtcgct gtgatcactc
     5581 ctatcgtgcc gccgcaggca cccttgcagg agctcatcca cggcccgatc gcctatccgg
     5641 taccggtgcg cggtaccagc gatgatctcg tatacggcat gtcgacggtc ggggaggccg
     5701 ggcgcatcct cgaccggcag gtgttccgca agttgggctg gcggccgggc aaacggctga
     5761 atatccgctg tccggaacac ggtgtcctgc tggtggctcc ggcccgtgac ggtgcggcaa
     5821 tcgtgacacc cgacgagttc ttccgggtgc actacaaact gcgacggcgc gtcaacctgt
     5881 tcatcggtga ccgggtgctg ttgatcggcc gagtctcccg tagtcgcctc gtcgtccatc
     5941 cacctgcggc gatggatgag ttgttcgccg agagcgtgcg cctgctggac cggtggtaac
     6001 gatgacatca ctcaaccgat cggccggtgc gtctgccgaa actgtcgccg ccgcaaggct
     6061 tttgctgtcg caaatgggaa tctctccggc cgatctcgtc tgtgctggcc cgactgcgcc
     6121 aacgttcggc gaggttatcc ccaaggtccg gaagatcctg tccccgggaa cactgcgcac
     6181 atataacacc cacttcaacc ggctgctgga tctgtggagc gaacagcgga tggacgacgt
     6241 gtcgaaaacc gacctggagg aagtcgcgca gacggtccag gccaccgctc gcaccacgcg
     6301 agtcacccgt ggcgggggcg gcgctgtgga gaacttcgtc agcgccatcc ggtgtgtcta
     6361 ccgctttgcc gaggacaacg gctggatccg gtcgtcggac atatacccct gtgccgagga
     6421 cactggtgcg gccgcaacca ccgcgaagcc gaatccgagc ccggccgcag caagcgcgag
     6481 caccgccgcg gcggcacgca cgatcggctc gcctcggcgc atcacctgcc acgcttcctg
     6541 cggatctggg cgatcagggt atcgctgccc caccaggtca gccgaccagc gacggacatg
     6601 tacaggaaga acgcgagata gaccaggaca gcaccgatct cgtcggccca ccccggaatc
     6661 cggtccatgc ccgcgaacgc cgcgatcagc atcgccacgc cgagcacgat cgccggaatt
     6721 gccagtgcgg cgatatcggc atcggcctgc gaagccgttc tcggtgtggt gttgtcggct
     6781 ccatggcgtg gttgcttgcc ggtggcgtcg acgccggggt tggtgctggt catgacacat
     6841 gcccttccgt gtgtgcccct cctgaaaggc aaagagcggt aacgattcag agggtgatgg
     6901 ggtcgccgta gacggtgacg gagttgtccg ccgtcgccgt cgacatggcg gcggtggcga
     6961 aactgcggag ggtgaccggg cctagacacg cgtcgacttt gacctcgacc tggtcggcgg
     7021 tgatcgaagc atgcgatgcg gcaaggggtt tggacccgaa cgggatcgtg gcgatggtgc
     7081 ccggtttcac cgtggtctgg atgttcgggg tcaccgaggc ctgcgcgccg acgctcaccg
     7141 agggcgggta gctgatgttg accgagacgt tgggcccgaa cgacagcccc atacccaacg
     7201 tgagaccggt gctgacgtcg atctgacagc cgacctggta gccgagggtg accgttgccg
     7261 agttcaccgg tttggtgccg ttgccggtga tgtcggcggt cgcttcgagg ctggcgaacc
     7321 cttcgcgact ggtcggcgtc gcgtccagtg cgggccaacg gtcaaggctc tcttgggttt
     7381 tggtgaccga tagggtccac ccgtcatcgg tgccgatatc acggcgcttg tcggcggtga
     7441 tgtcggcgtc ggcggacccg cccgcccaca cagcggcgac catggtcgca accaatacac
     7501 ccgcgcacgc ggtcgcggag ccgctgaaac tcatgaaatt tccttccgag atacagcagg
     7561 gaccccgggc aggcccgggg ggatcactac gagcacgccc ggatgcatcc accgtggcaa
     7621 tctatacaac cggtcagata gttaatgtgg agttcttcac acgccccgct gcaccccatt
     7681 tctgacaact actttcggtt cggtcccgcc tgggctgcgt gtgggatcgg ccagcagcta
     7741 ccgaacccgg cctcataagg catataggcg cggcgatgaa cccgcgtccg gaggtgatgc
     7801 gacccgaaaa tgactgcgag cagaccgaaa tcggtgatcg gatcagcatc cggtgtcgat
     7861 tgcccggtcc cgtgcacctc gagcgcatac aagtgtggac acccttggag ggcactgcag
     7921 aacctcacag gattgcgcca gcgcccaacc tgccccgatc acacctgctg tggcgagcag
     7981 tgcgtgcgac gagcgcggcc cggctgcgtc aacaacccga aaacaccacg gcggcagcca
     8041 cattcacctc gcacaccacg acatcgtgaa aggtactggg acagagccgt tatctggaca
     8101 gacccggttc gcgcagagtg tggagtcgtc cggctggtgt gcggcggtgt ggtggcgtga
     8161 ttcgattctc ctgtccgtgg ccgtagcatg acaggtttgt tggcggaacg attgagtgtc
     8221 gtaaccatcc aggtttcgtt ccgaattttg gctgcgcaca ggacttttcg gctctaacgt
     8281 tgttgtctgt gtggtcggtt tgcttgcatt ggtgagccga tccttccggg tgttcttatt
     8341 tcccctgatc tgttgtgtcg agtgcgcgat cagtccggtg tgttgtgaca gctgtcgaag
     8401 ttcaactgga gtgaggggac gacgcatgac tatcgagatg ccggtccaga cggacaacca
     8461 gcagcgtaag agtttgagta ccggtgcggc gcatcagttg gcgcacacca ccaagtccga
     8521 accgcagatg cagggcatca cctcgcgatg gttgacccgc atgctgccgt ggacgcaggt
     8581 cggcggtggt gtgtaccggg tcaaccggcg tctgacccat acggtgggca acggagaggt
     8641 ggaattcgtc gtcgacggct cgcaggccag ggtaattccc ctggagttga ccgagcttcc
     8701 gcagttgcgg gacttcgacg acgaggaggt gctggccgcg ctggcgcacc ggttcgaaca
     8761 acgcgatctc gatccgggtg tggtggtggc cgagttcggc aacccgatgg atcaggtcat
     8821 gctgatcgtg cacggcaagc tcgccaagct cggtaccggt gaatacggtg agcagacccg
     8881 gctcggtcta ctgggcgacg gtgatttctt cggcgacgcg acgctcaccg acgccgatgc
     8941 catctggccg gtcaccgtca gaaccatgac caggaccacc atgctggtgt tacggcggga
     9001 atcgctgctg cagatgcttg agcaggcgcc cgcgctgggg gagcagctgt cccgcgtcgc
     9061 cgccgaaccg gcgcggccgc agaacaccaa gggtgaggcc gacattcaga tccagtcggg
     9121 tcatgcgggc gagccgttgt tggaaggtac gttcgtcgat ctcgatgcgt cgccgcgtga
     9181 gtatgagttg agcttggcgc agagtgtgtt gcgggtgcat acccgcgtcg ccgatctgtt
     9241 caacgatccg atgaaccagg tggagcagca gttgcggctg accatcgagg cgctctacga
     9301 acgccgcgaa cacgatctgg tcaacaatcc ggacttcggt ctgttgcaca actgcgatct
     9361 caagcagcgc atctactccg aatccggcgc gccgaccccg gacgatatgg acgacctgct
     9421 gagcatgcgg cgcagcacga aactgttcct ggcccacccc aaggcgatcg ccgccttcgg
     9481 ccgggagtgc agcaagcgcg gactgtaccc ggatccggtc gaggtcgacg ggcaccgctg
     9541 tttcgcgtgg cgcggtgtgc cgatcttccc gtgcagcaag atcccggtca gcgataccca
     9601 gaccacctcg atcctggcga tgcgtaccgg cgagaaggac cagggtgtga tcggcctgca
     9661 ctagaccgga attccggacg aatacgaacc aagcctgaat gtgcggttca agggcatcga
     9721 cgaccagtcg atcatttcct acctcgtgag ctgctactac tcggcggccg ttctggtgcc
     9781 cgacgcactc ggaattctcg acaatgtcct ggttgcccgg caggccgact gaccggggtg
     9841 atgagcgatg tcggtgctct cccgcgccgc ggcgccgatg gccacgtccg acgtggccac
     9901 cgccgtcgcc gccttgctcg ctgatttatc gacaaccgcc cctgcggatc tactggcggc
     9961 gcagtccgcg gaaggtgaag tagcgcaagg agattcaccg gtgccccgac acctgctcgg
    10021 tccgcgggga ctcggcgccg cagcgctgcg actgccattg ccggagctgg atctcacccc
    10081 ggccgaggtt ctgcccgccg acgcaccggc gcaggaggac attcccgcgg cagttcccgg
    10141 cagagccgtg attccgctcg gaccgacggg attgggttcg gccgctggct atttccaccg
    10201 ggtcaccgcg gagccaccgt cggtcgaacc gctcggcccg gcggaacccg ttgcgggaac
    10261 gctgaatcca cccgctgtgc cccatccggc cgagtcggtg gacgagatcc gccccgcctc
    10321 ggtacaccgg atacccaccg cgccaactgg attgggggcc gcatcggcgc tgctgcggcc
    10381 ccgctctacc ccggcgggta ccaccgaatc gacggtgcgg tcctcggtca taccgccgct
    10441 gtactgtccg ccgccggtcc gcgacaatcc ggaactggcc gagttggtca acgatggact
    10501 cattgcctgg gccgccgaaa tcgggctcta cgaaggcaga ttggatgagt tacgggatgc
    10561 cgatttcggc cggttgatca tgctggccca tccagacagc gacgatccgg accggctgct
    10621 cgcggtggcg aaatgcgcgg tgaccgaatg gtcggtcgac gattactact gcgaggagga
    10681 cgcgccggac accgcaccgg acggatcacc gtcgcaggcg tgggccgaac tcgggccgaa
    10741 actggaaatg gccgccgcgg caatggatcc ggtgcatctt ccggcccgat acgcgccgca
    10801 gttggaggag gcgctgcagg ccgatccgat cctgcgggcc ttccgcacct ccttcgaaca
    10861 cttcgcgcgg tacggcaccc cgacacaggt cgcccggctg cgcacggaga tcgcgggctg
    10921 gttcatcgcg ctggcggccg aggccggatg gcgggcggcc gggcggatgc cgccggtgtg
    10981 ggagtacctc accaaccggc agccgcacag cttcctgccg tgtatggcgc cgctcgacgc
    11041 ggtcggcggc tatgagctgc ccgccgcgga atacgccgac ccgagggtgc gccggctggt
    11101 caccaccgcg gcgctggcct cccagatggt gaacgacctg tactcgatgg cacgcgaaga
    11161 cctttccggt ggaagggaat tcaacctgcc gacggtactc gccgcggagg agggttgttc
    11221 gcgacacgac gccgtgcagc ggaccgcaga agtgcacgac gaactcgtgc accgtttcga
    11281 acgagaggca accgtcctag ccgccaccgg cactcccgag ctgcgccgtt tccttggcgg
    11341 actgtgggcg tggctgggcg gcaaccgcgc ctggcacgcg gaaagcaaac gctaccggta
    11401 acgcggcgcc cgaaccccga cacgaccgcc tccctgagcc ggacgtggcc tgccgatcga
    11461 ttcacgcacg accttccccg atacccgtga cgagagagga tgacccggca tgtccacgga
    11521 agaaaccgga accggcccgg tgctacgcac cagctaccag agatccgttg cggcgtactg
    11581 gaacaacaac cccaacgacg accgcgtgaa caccgaactc ggcgaggtcg acggcctcta
    11641 ccatcaccat tacggaatcg gcgagccgga cctgtcggtg ctcgaagccc cgcaagcggt
    11701 ccgccagcag cgcatcatcg aggagttgca ccgcctggaa accgcccagg ccgctctgct
    11761 gctcgaccac ctcggcaagg tgggtcccgg cgatcggctg atggatggcg gatccggccg
    11821 gggcggaacg agtttcatgg ccaatcagcg tttcggctgc cgcgtcgacg gggtgaccat
    11881 ctccgaatac caggtcggct tcgccaatga gcaggccgag cagcgcaagg tgaccgacca
    11941 ggtggccttc catttccgga acatgctcga caccggattc gacaccggct gtatgcgcgg
    12001 catctggacc aacgaaacca ccatgtacgt cgacctgttc gacctgttcc gcgaattctc
    12061 ccggctactg caacccggcg ggcgctacgt gtgcatcacc ggctgctcca acgatgtcaa
    12121 cggcggtcgc tcctcatcgg tcagcgggat cgacgcccac tacgggtgca tgatccaccc
    12181 gcgcagcgag tacttccgcg cactggccga gaacaacctc gtgccgatcg acgtcgtcga
    12241 cctcaccgcg gccactatcc cgtactggga gctgcgcacg aaatccgaac tggccaccgg
    12301 ggtggagaag gcgttcctca ccgcataccg ggagggcagc ttccaatacc tgttgatctc
    12361 ggccgacaga gtcaggcgtt gagcgcgttc ggctcggagc cgaacccgga ccaggcccgg
    12421 tcggtccgcg ctgacccgtg ccccgtcgat gtcgattcat cgccggatcc gttccaccct
    12481 cgccgcgacc cgttccccga taccgggagt cgatatgttc acctgggtat acgagatgcc
    12541 gtcctggctg tcgttcctcg tcatcaccgg agtcttcgtg gcgataacct gctccggcgt
    12601 catcatcgcc agacccggag tgcgcaagat attcgccaga caaccgggca tgaacgaaat
    12661 ggtcacgatg gtgctgaccg tcggcggcgt cttctacggc ctgctactcg ggctcaccgc
    12721 ggcagcgacc tatcagtcat tcgactccgc gaacaccatc gtcgccgacg aggccgccac
    12781 gctgggcgtc ctgtaccggg aagtgtcggc ctatcccgaa cccgaacgcg gggtcctgca
    12841 gaaagatctg gtcgactaca ccgacaacgc gatcaacgta gcctggcccg ccctgcggaa
    12901 aggcgaggaa tcgacgatcg gaaccgcgct ggtcaccaga ttccagcaac acctgctcgc
    12961 cttccaccca caaaccgaat ccgacaagat cgtgcacgcc gccgccatcg agcagttcgc
    13021 ccacttcatt caggtccgcc tacaccggct cgccgactcc agcggcggca tccccaactt
    13081 gatgtggacg gtcatcgtca tcggcgccgc ggtcaacatc gcactgatgt gcctgttcac
    13141 cctcgaacac cgcaccgcgc acctggtcct ggccggactg ttcgccttct tcctcgccac
    13201 aatgatctac ctgatcgccg ccatggacta ccccttccgc ggcgacctca gcatcagccc
    13261 cgaaccattc atcaccacct acatcatcgt catggggcaa accagccact gacccctcac
    13321 catcgaatcc tgttctcgcc cttcgagttc gaaacgaggt agcagcatgt cgagcaaaac
    13381 accgtatcga gcggcgacac ttctgcaacg cgcggttctc gtcgccgcca tcggtgccgc
    13441 ggcctgcgcg tgctccggct cgcatgactc cgccgcggca ggaagcctcg acgcgggctt
    13501 cggatccggc ggcaaggtga caacagacct cggctcatcg gccgaccgcg ccaacaccgt
    13561 gacaatccaa accgacggcc gaatcatcgt cgccggatcg acccaggacc ccgcccaggg
    13621 cgacaacttc gcggtcgtcc gttacatcac cgatggccaa ctcgatccga gcttcggtga
    13681 cggcggaaaa gtcagcaccg acttcggcag tgaatccgat atcgccaacg ctgtcgtgat
    13741 ccagccggat ggaaaaatcg tcgcggtcgg cactagtcac ggcaccgcca gtggcgacga
    13801 tatcgcattg gcccgatacg ccgttgacgg caaactcgat gcgagtttcg gcaacggcgg
    13861 gaaagtcagg acggatctgg gcagtaaagc cgatcacgcc aacgccgccg cgatccaatc
    13921 cgatggacgg atcatcgtcg ccggttcgac ccaggatccc gcgcggggtg acaatttcgc
    13981 tgttgcccgt tacaccaccg atggcaaact cgatccgagc ttcggcgacg gcggaaaggt
    14041 cagcaccgac ttcggtggtg aatccgatat cgccaacgct gtcgtgatcc agccggatgg
    14101 aaaaatcgtc gtcgtcggca cgagccatgg caccgacacc ggagacgaca tcgccctcgc
    14161 ccgatacacc accgacggaa aacccgacat cagtttcggc aacgacggga aagtcagcac
    14221 cgatctgggc agcaaagccg atcacgccaa cgccgccgcg atccaatccg atggacgaat
    14281 catcgtcgcc ggttcaaccc aagatcccac ccaaggcgac aacatcgcca tcctccgcta
    14341 ccacgggtaa accgataccg gcgcgaccgc atctccacag ggtcaacaat ttcgaatggt
    14401 cggtagccag gaacgatctc gtgctacccg accgattcac ttcctgagca gcccgagcgg
    14461 catcgtcgac aacgcccctc tcgcaccctc cgcggtcgag ccgtgaaatg gtcgagctca
    14521 agcggacggg tttccggtcg cgggtccggt agtacaactg cctggcccgc agatccagcg
    14581 caccgaacat atgccggaca ccttggatgc gacgataggt cgtccgcagg cgacgcgact
    14641 ggcgagcggc gaaccagccg tggccactac gaggttgcag gttctgcggt ccgaacccgt
    14701 ccataccgat ccgtcctgtc gtcggtaacg aatgcccagg agcggtgcga ggatgtcgct
    14761 ggacatcggg ccgcgaaacg acagggacgg tggccggtat cggcgaccgt cgacaccctc
    14821 gggaaaggaa tggtcatact tttgcgcggt atccgtggtt tttccaggct tctgatcatc
    14881 gcggccgcag cggcgttgag cgcccccgcc ctgatcggga gcggcgtcgt gcgggctgag
    14941 accgaggcgg aaagacaaca ggccgcagca caatcggttt tcgaaaatct tctctgcaaa
    15001 gaggggaatg ggaagaacgg actcgagccc cacaccgacg actggtatca cgactggatg
    15061 aagatcgaag acagtgcacc ctacgagatg aaaggcaacg gctctccagg aaaatcggca
    15121 cggaagacgc tctacaaagt agcgaatctc aaccccgaga ctcgaaaaga gatatgtgaa
    15181 aatacgacca ggtatgcaaa tgaactagag gcccagaccg accacctgaa aggcgatctc
    15241 aagctcacgt gccgcgtcaa catcgatcgc cgcatcgaca aggacggcga gctggggaag
    15301 acgctcaatt gcggggactc agcggggcag gcgaagctcg tcgacacgaa gttcctcgca
    15361 tacaagaaaa tcaccgacta cgatgacgaa ggcaattacg gcgggcccaa gaaatagctt
    15421 tgaggtctcc ggtattcggg taggcgaccg agcggaccct gaatacccgg aggcctcgtg
    15481 ttccgagata ctaacctcga tttttcgtgt gtctggcgtg ctggctcgat ctggttgggt
    15541 ggcccgtctg cggccgtgtc ggtggcggaa cggcatgacg ggctggcccg tgcagcgggt
    15601 gggctgccgg gttccacggg cccggagtgg tccttcctga tggtcgtcgg gactgttttg
    15661 gtgttggtca ggtggtgttc agtcgggtca gcgcggtgag cgcccgcccg gtcgtcggtg
    15721 cgggagcggg gcagccgcag catggctcgg cgagcgggct tggggaggtt gcagatcttc
    15781 cggtggacca ttcgtttggg gagggtgtag tgagattcgc gagaatcgag ttgatagctg
    15841 tggtgctgct gatgagcgtt agcctggagg taacgacatg ctcgtcgagt gagcgttacg
    15901 acagcgctgg tgctatcact gtaaattgtg cctgatccac aattctgatg ccgttgacaa
    15961 cggcacgatt cctggcgggt aggggtttag gtaggcccgc cgtgttgctt gcatggcgcc
    16021 gacaccggag acgatatcgc cctcgcccga tacaccaccg acggaaaacc cgacaccagt
    16081 ttcggcaacg acgggaaaac cagcaccgac ttgggcagta aagccgatca cgccaacgcc
    16141 gccgcgatct aatccaatgg acgaatcatc gtcgccggtt caacccagga ctccacccaa
    16201 ggcgacaaca tcgccatcct cggctaccac gggtaaaccg ataccggcgc gttccacaag
    16261 gtcccggccc tcgagcaggg gctgcgccca ccgcggcgcg gtgtcggcac acggtgatcg
    16321 ggtcgcggcc ggtcattgcg atcgtggcga ggtgccgcgc agcaccggcc acgcctgccc
    16381 accagtcaca ggcccggcac caatcgttcg gccgtgtcgg cgagtgcggc cagccggtcg
    16441 gcaccatatc ggtgctcggc cgcgacggcg agggtgttcg tcgacgtaag cgtcgaccgc
    16501 gctgcggagg tgcaggcacg atcggtggcg tcgcgggcgg cggtggccgc agacatttgg
    16561 gttcttctgg gagttcaccg tagcaacgat ctcgctgcat cgagaggtca cccacggcgg
    16621 agttgggagt ttccggatcc agacgctgat cggacacgtt ggtggtggtc ggtggtctgg
    16681 tgagtgtgtt gtgtcggatg gtggtggccg tcgtgggaac gtggtgggcg gtacggatgg
    16741 tgttgtcggt gctgtgtgtt tcacggtccg tgttcgtggt ggtgggtggg ttgtcccatc
    16801 cgtggtgggt gtggttccga atggtctctc ggaccggtcc tgttgtttcg gtgtgatcgg
    16861 ttgtcctcgg tttcgtcatc gatgtgggag gtcggaatga gtgttcgtgt gcgggggatc
    16921 ggctcggtcg tggcggtggc cgcggtgatg ttgtgcgctg ggatcggttc tgcgggttcc
    16981 gcgtcggcgg agccgccgtg ggggacgcat tgtaagggtg cgaaggccga ggcgaagaag
    17041 gagaaaccgt tcatcatcca ggcgtgtcag cgtgcctaca gcgccaaagc ccgcgccatc
    17101 atcgccgacg acgccaccaa gaccgacgcc accaccaagg ccgacgccgc cgctgacgcc
    17161 cacaccgccg acgacgccac cgacgccgcc ttcgaggccg cccaactggc cgccaaggcc
    17221 gccacctcct ccaaggtcac cgccgacgcc gcggtcgacg ccgccgaggc cgctcgtgca
    17281 gctcgggatg agcctatgga tgtggcgctt gccaacaagg cagccgaggc cgaggagaag
    17341 gctgtggctg cgtcgcggaa ggctttcggc ggtcccgggc aggtgaagat cccgcgactc
    17401 acctccgccg ggtagtagag cggtccggga tccgaagtcc cttggcgtac atgaagagga
    17461 gggtctcgtt tgaacgttgg gtgaccaaca attatcgagg cccttctcgc cgcacggtct
    17521 gtgacgatcg atgacgaggt ggcggggccg cggtggatgc cgggtgcctg ccggtactca
    17581 cctgatgcgg agtcggtgtg cgtcgcgggt cgatacagtc gctgttcgga tccgctcgcg
    17641 aagcacaccg gctgcggtat gtcgatcccg tgggctgtgg ctgacccgaa aaatgctgaa
    17701 cgcgaggtac gtccagcgat gctcgaagtc caatccagca tcaccgacaa gcacgaagcc
    17761 catcatcatg atccgcgaca agggttcacc agccacgagt tcgaaacgag gtcctggttg
    17821 tgttcaccgg tgccatcccg gtcgagcact acagtctcca acgccgacgc gactacggcg
    17881 accaccaaac ggcactgacc gcttctttcc tggaccccac cgaaccgcca tcacctccgc
    17941 cgcctgaacc agggcacgaa cctacgcgtg cccgaccagc gcaactgacc cggtcggctt
    18001 ctcaatcctg cctgctcgcc tgtttacgat gcgccaaggt tctgcggtgc gctgcactgg
    18061 atcgcgacgg cgaatctcta ccttgcccaa ccgctgttgg gggttctcac ggcgccttcg
    18121 gtcgggagtg ccgattcgtg atatcgccag agagagccga ctgatgcgga tccgtccgca
    18181 cgcgatccct tcggtggtac gcggtttcgg ttcggccgag agtcgggggc agcccttcgt
    18241 gacggcctgc gaccagcacc agccagcgag ttcgcgggcg atggcgatgt tggcaatcgc
    18301 tgtgtcgaca cgccggctgt gtcccgtcgg cttccgatcg tgactgctct gctggggttt
    18361 cggtttatgc cgcaattgat gtttcggctc gatatggacg cctcgcttgg atttgtccca
    18421 ggatcggtcg cgagttgagc gaggacttcc ggagttgacc tatccgtcct ggtagtggtg
    18481 acaaatagcc ggtgcgcgga tgtcgttgag cactggcaag agcgggccgc atatatgcgt
    18541 ggtatccgtg attggtcggg ggctcctcgt cgtcgcgggt agtcacgcaa ctattacagg
    18601 actacagctg cccggctcgc gagcccacgg ctatctgtcg agctcgcggg tggatggtgc
    18661 gaagcggatt cagctttcgg gcagcgtgtc ggggtcgacg ctcgcagcgc gcaagcgttg
    18721 cagaaccgcg gcacgcgcgg cggcgagggc gaactgcggg tccagcattc gaactcggga
    18781 caccacgccc tcgccgaggc tgtcgatctc gtaggcgagc tgatcggaat ccgtgtgctc
    18841 gcacagctgg cccgcctcga tcgcctcgtc gatcgtcgcg gtgagaaacg cgtgccattg
    18901 tgctgattgc tcgatgagcc ggtcgtggat caccccgggc cgatcgtcga attcccgata
    18961 gacgatggag aagaagcatc gccccggcag catctcgcgg gcgtagaagt ccaggcggcg
    19021 ctcgtgtagc gcccacagcc gctgcaaggg ggttggctgt tcgagcgccg gtgcgatgat
    19081 ctcggtaacc cattgtgtgc tggcgtgttc gagcgccgcg agctggagct cttccttacc
    19141 gcgccagtgg gtgaacaacg ccgatttggt gacgtccaac cgcgcggcaa gctggctcag
    19201 cgacaacccg tcgagtccct ccaccgatgc cagtgacacc accgcatcca acacggacgc
    19261 ccgggtacgg ttcccgcgca actttcggcc atcggtctca gtcatcacaa acaccaatcg
    19321 agggcagagg ccagatttgg tcacgtgacg taaccattgc ggatggataa cccgctcgga
    19381 catgtctaac cgaatgttcg gattctatat tccgctaggg actgaccggc gatatggagc
    19441 actgggaaac ctggggtgtc ctcaggaagg tgcataccgc tcggtcgccc ggtgttgtcg
    19501 gcaggtgcgg acctgagaat actcatggcg gttggtggcc atccgtgggg atgtcgtgcc
    19561 aaagctcgtt gagttgatgc gactgaccag attgtcgact gatttggagg tacaccgtgt
    19621 cggcccgggt tcgggcctgg gacaccggcc gaggcaaggt tgtcgatcaa ggagtctgaa
    19681 gttcgcgctc acggcagcgt gcactcggaa ggcgcggcgc tcggtgccct gcctgtcgac
    19741 ccgacctcga tagcaacctg tctcccgcca tctcacacct gtcgtagtgg cgaatgatca
    19801 cccgggtcgt caacgaccag ccaccccggc ggtatcggtg ggggtggctg gtcgtgcgcg
    19861 ggtgggggtg gatcatcctg ttttgcggcg gtgccgagac gtgccgctgc acagcggatc
    19921 ggggtcggcg ggtgtggggt gcgtggctca ctcggagggg tcatgcccgg cgtgggcgag
    19981 gagtcccgcc gcggtaggtg aacgttattt gggcacggcc gtgaatatca catgccggac
    20041 atggaggcct gccggctgga ccatgccgtg tgggtcgaga tcggtttggc cttcatcgca
    20101 tccgagtccg tggtcgtata catgggcgac agtgttggtg tgttgcgcac cttgaatgcg
    20161 tacagttgtt catccttgct atgttcgttt tctgcgatgc tgaagcagtt gttcaattcc
    20221 ggattttcga tgcggccggt cttttctttg tcgttggcgt cgtcgaggtg gtaggtgaat
    20281 gcgcccgtag cgtgcctggg tgcgttcgcg agggcatcgg cgggagcgat gaccgacagg
    20341 ggacagcgct cagcagggcg agcagtgtga gacgaagacg cacagggttg ccttttggtt
    20401 ggtgttgggc cgggccgttt ctcgtggagc tggtctcccc tgagggggta tcgaacgaac
    20461 ccgccgtgtc tgcgttcgtg gtggaaccgg tctcggatgg gctcggggaa tctgtggcgc
    20521 aatccgctcc ggatcattac ccgcgagcgg gcgcgccttg gttgtttggc cggtgcgggc
    20581 accgcgccgg ggcagtgatg atcgtgatgg tcgtgctggt cggagagtct gatcagccga
    20641 agccgccgct gtgtcctggc tacggtatct ccgggccggg ttctggtcgc gggttcctgc
    20701 acggcccggt gtggttgggg gtgtcacgac cagagtgccc cggcggaagg tgtttcgttg
    20761 ccaggcgtgg cgccggattg gttctggcca gaaatagaaa ccttccggcc ggggccaatc
    20821 catcggggga tgggtgacga ataccgctgc gggtgtcccg cctttgtgcc gtcgtgctgt
    20881 gcttcgagac ggaggggtgc gcatctgttg agagacaacg tgttcggtcc ggttcgtgat
    20941 cgatggccgg gccggggcgt cgatgcctgt gcggtgcctg gcactgcgac tgttcgatat
    21001 cgaatcattc gaatcaagag gagaattcat gctgctgggt gttctgagcg cgctgttgac
    21061 cggtctgtcg aacgtggtgg ccgcgttgtt gtccggggcc tgatcgtgtc ggttcggggc
    21121 ggaacagcgc ggtttcgccc cgaaccgacg cccccggtat ccattcattc tgaatcctga
    21181 attcgtcagt ggtcgtggtt gtttcgtgtc gaaggtgggg aagattgcgc acgcgttcat
    21241 ggccgatgga tccgagccga ggttcggcca cagcggttgt cgcactgatc gtttccatgg
    21301 cggcatgtgg tgcgtcggcg gccgagcccg ccgaacccgg tgtgccgttg cagaactgtc
    21361 cgagtctgta tgtgctggca gtgcaaggga ctggtcagtc c
//
