LOCUS       NZ_KV411303            26097 bp    DNA     linear   CON 12-FEB-2024
DEFINITION  Nocardia terpenica strain IFM 0406 scaffold1, whole genome shotgun
            sequence.
ACCESSION   NZ_KV411303
VERSION     NZ_KV411303.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardia terpenica
  ORGANISM  Nocardia terpenica
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 4641778)
  AUTHORS   Buchmann,A., Eitel,M., Koch,P., Schwarz,P.N., Stegmann,E.,
            Wohlleben,W., Wolanski,M., Krawiec,M., Zakrzewska-Czerwinska,J.,
            Mendez,C., Botas,A., Moris,F., Cortes,J. and Gross,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-APR-2016) Pharmaceutical Biology, University of
            Tuebingen, Auf der Morgenstelle 8, Tuebingen 72076, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 30-JUL-2014
            Assembly Method                   :: CLC NGS Cell v. 7.0.4
            Genome Coverage                   :: 118.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/12/2024 01:56:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,832
            CDSs (total)                      :: 8,760
            Genes (coding)                    :: 8,562
            CDSs (with protein)               :: 8,562
            Genes (RNA)                       :: 72
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 40 of 198
            Pseudo Genes (incomplete)         :: 174 of 198
            Pseudo Genes (internal stop)      :: 9 of 198
            Pseudo Genes (multiple problems)  :: 23 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:51:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 924392
            Orig. end                         :: 950489
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KV411303.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26097
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="4"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..26097
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26097
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16097](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16097)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(290..2023)
                     /locus_tag="AWN90_RS04260"
                     /old_locus_tag="AWN90_04285"
     CDS             complement(290..2023)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012691068.1"
                     /locus_tag="AWN90_RS04260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_04285"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_082870536.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.3e-29, bitscore:
                     101.3, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATTTSGTAPIDVVGWEQTYSSVPTGLKPVVLSVDDDPVVSRAVV
                     RDLRQRYGRKYQIIRAESGRQGLEVLREVKLRGQPVAVIIADYRMPEMDGLDFLERSID
                     SHPLARRVLLTAYAETAVAIDGINIVDLDHYLLKPWDPAEEKLYPVIDGLLESWCADDR
                     KPVVQTKVIGSRWSARCSEVREFLARNQLAYRWYLVNEPEGDRLLRAAGVEEDRCPVVV
                     TSTGKVLVRPGNAELAEVLGLTTSPSTGFYDAIVIGGGPAGLSAALTAASEGLRTVLIE
                     RTAPGGQAGQSSRIENYLGFPDGVSGAQLAERARRQALKFGAELVTTQNAVKLEVRGGA
                     RRVRFTDGSIIDGHTVVVATGVSYRRHPAAGISEFTGRGVYYGFAMTEATLCKGMNVHV
                     VGGANSAGQASVYLSRTARSVAVIVRADSLHKSMSHYLIEQITNTPNIRVKLNTEVVEV
                     GGNAHLERILVRNGTSGEEEELAGECLFLFIGAEPGTDWLADVLVRDDRGFLLTGPDLL
                     ADGGPIPGWTLDRPPQQLETNVPGVFVAGDVRAGSAKRVSSAVGEGVMAVMLVHRYLAQ
                     S"
     gene            complement(2065..3621)
                     /locus_tag="AWN90_RS44890"
                     /old_locus_tag="AWN90_04290"
     CDS             complement(2065..3621)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1285: ferredoxin fdxC"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019604.4"
                     /locus_tag="AWN90_RS44890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_04290"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_067577862.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.1e-09, bitscore:
                     35.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPHVITQSCCNDASCVFECPIDCIRPHPDDPAFATADMLYIDPDS
                     CIDCGACVDVCPVDAIVFDDELPPAAGRFAELNAAYFQRFPLTAALAAATRAVPCRSPA
                     RAPLWVAVVGSGPAACYATEELLRRSTAEIDIFERQPAPWGLLRYGVSPDHPRTRRMAN
                     TFAALLDDERVRLHLDVQIGTDITHDDLARRYHAVVYATGAPASRSLGIPGEDLPGSHS
                     VAEFVGWYTGNPDYADMSFDLSGDTVVVIGNGNVALDVARILTADPDTLPGTDIADHAL
                     DALRASNVREVVILGRRGPTEAAYTTSEFLELGYLPNIDVVIDPVDLELGQTAARALDD
                     DPASAMKMALAQEYSRRFPGPGHRRIVLRYRVAPIELFGSGHVAGVRVRPNGFGAGDDP
                     AANCRPESIAGSPVLRSIGYRSVPIPGVPFDEQHGIIPNEHGHVLDTSGLPVAGVYVTG
                     WAKRRPRGGIGTNRIDAGEVVDCLLSDFANGLLATPQCGRDDLTEPTAARRPRALEDHP
                     G"
     misc_feature    complement(2572..2574)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3903..4079
                     /locus_tag="AWN90_RS46815"
     CDS             3903..4079
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWN90_RS46815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_171983112.1"
                     /transl_table=11
                     /translation="MSEQRIGFRKYVGDLIDSAKDTMDASKDCADDILDRTYGVERGLR
                     NTVRAVFGRDKKP"
     gene            4112..5593
                     /locus_tag="AWN90_RS04270"
                     /old_locus_tag="AWN90_04295"
     CDS             4112..5593
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015094.4"
                     /locus_tag="AWN90_RS04270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_04295"
                     /product="AarF/UbiB family protein"
                     /protein_id="WP_067584336.1"
                     /transl_table=11
                     /translation="MGHLAADFLAAQDRGMPTPRAIRRRQRRAVATRKALNRLGPFYTK
                     LGQVMATRPDFVTTIMITELEKLQDRCSISPFSSFETVLTEDLGAQWRQMFADVDPDSP
                     LGSASLAQVYRVTTAAGQVAALKVQRQGVRETFTADMAITMRIAKLLNRIFPRIHAMLD
                     VETALRVVFDAMESELDFTIEANNMNEARAMVAKYSCLSIPKVLHATPRVLIQSMAPGI
                     SIREADPTAFTGREREQIGRDLLSFMYNGYFVHRFFHADPHPGNIFVHPGQGAWLLDWG
                     MVGRLDRHLSSAMLLVLSSIAQNDGIAMAKAWMELGHPMPWADVRGFADDMSLLVPKLC
                     SRSMGDLSLGVTLTALLRAAAKRGIRSSPLVALVGKSFGNIEGSVTCLTPELSVVGVFQ
                     DTLTDVLRGMASDLISKEQLGRSAIDVYLGGTTFLSQTREILDSVSGGQFGIRVGIDER
                     TVFKAQTIGSQAKPLVLGALAAGAIVWLRGLRRAG"
     gene            5624..8254
                     /locus_tag="AWN90_RS04275"
                     /old_locus_tag="AWN90_04300"
     CDS             5624..8254
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015155.4"
                     /locus_tag="AWN90_RS04275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_04300"
                     /product="MMPL family transporter"
                     /protein_id="WP_067577864.1"
                     /transl_table=11
                     /translation="MFDRTHTTVERSTLRRCGEWIVRHRYLVVIGWLLCAIATALAAHA
                     VGPRYDDGGAVPGTDSRVAQDLLAARFPVYAGSSGVVVFHATNDRLSATLVDDAVRRIA
                     GLPHIVRVIDPFAAAGALSEDKRTGYAAVQYDTRFSTGDSEPLHRLIDATATARAAGVQ
                     VEVGGPIADLAGLHAPRTSEVLGVTAALAILTITFGSLVAAGLPVLTAVAGLLVGVGTA
                     ELASRLLPQMPEQSVPLAVMIGLGAGIDYALLIVTRFREFLAEGADVAAAVTESMATAG
                     ESVLVAGLTVTVSLLGLWVTRLPVIGAVGTACAIAVGAALLSALTLLPAVLSIIGTAVN
                     RLAIPVTTDRGGAGWARWGGRISKSPWFFVIGSVATLLVLALPSAALRLGIADAGVQPQ
                     SQTQRRAYDLIARDFGIGANGPLLLVTGLTGARQEGTDLDRLSAAVRAAPDVARVAPVE
                     IAPDGRAAVLTVVPAHAPSSPATDNLVHRLRDVTIPASGVSLRVYIGGATASGIDMGAT
                     VRSRLLWFVGAVVALTIVLLTVLFRSVLIPLKAAILNLLSVGAAYGAVVAVFQWGWGAS
                     LIGLDGPVPVYPFFPAVIFALLFGLSMDYEVFLITRIHEAYRGGAGTFGSVIQGTAATA
                     RIIGAAALIMIAVFTAFVLQADPTVKLVGFGLAVAVLLDATIVRLMLVPAVLCLLGVYA
                     WWFPTLRRGAMAGCRNSKYGHLFCLLDQDKDGYLDRGDFEAIAGAATRLADPHLAQNIR
                     TGFQDWWRQLPADGHDKISLPDFIDANYRGLAADPSYYGNGPGQVFEILAATVASGDGT
                     IDEGNFVRLFRCFGVPDSAIRKGYRRIDLDRDGIITKSEFAAAVREYFTASKGAVVGNY
                     IFGPI"
     misc_feature    8436..8451
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.08"
                     /tool="antismash"
     misc_feature    complement(8509..8525)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.51"
                     /tool="antismash"
     gene            8782..10017
                     /locus_tag="AWN90_RS04280"
                     /old_locus_tag="AWN90_04305"
     CDS             8782..10017
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /locus_tag="AWN90_RS04280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_04305"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_082870538.1"
                     /transl_table=11
                     /translation="MQAHRAEQQGSGLSVGARIELRRHQFGLSRRVVANLVGRSEEWLR
                     LVESGRQSLDSIRIIASLAEVLGIENIAELIEWSTGRHAINRDSGQDHILELFKHAIVD
                     PLDINAAASSPNVSIEELRHGLVRCEEIWHSSGERYSLVAQLLPSIVRDSGRLFWTTMD
                     PAVGEIAIRANHMTRRFLNRMNWHNLAAMVADRSMCISRCLKTSLWTTASAWHVGNAML
                     RLALPIEAHDIATAAINTLDETVDDTRKQLILRGALLLLAAEAAAMTHNVREADELITL
                     ATHLSRELDDEQMVGDIAFGPMAVGLARIEIALLRAEFSEIPRIAAQVEVPEGYSVGDL
                     AHFHIALAYAFAHRNEDVAAAYSLSRAADLCPEEIRYDKYACETMEQLIHRENRLVRRD
                     ITKLLARITAST"
     misc_feature    9403..9405
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9445..9447
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..11101)
                     /locus_tag="AWN90_RS04285"
                     /old_locus_tag="AWN90_04310"
     CDS             complement(10001..11101)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014983661.1"
                     /locus_tag="AWN90_RS04285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_04310"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_067577868.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2e-42, bitscore:
                     143.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTADSGRCSVTGSETTSAPVNLAGIRKQVDGILDRFLRQQAHSLE
                     KRGLPREITDIVHDFVFAGGKRLRPTLVALGWLAAGGDSAVPTPVIQVAAALELCHTAV
                     LVHDDIIDNSDTRRNRPTVHRVVSQRYRTRPDADRFGMRAAILLGDLVMLWCDEMLHTA
                     QLTPAQTATVIPIFDTMRTDVIYGQYLDLATSGLSGGDVEKALEIVRYKTSSYTFECPL
                     RMGAALADASIRIQQDLRAYAGPLGVAFQLQNDLEGVYGAGASSLDDLREGKHTALLAF
                     AVRHADPAQSARLYELVGNPELDASGAATCREIFDIVARGQVQQMIRTRWERAQGVLDR
                     ATFPMAVKDALRAVADNVTRGITWMR"
     gene            complement(11098..12261)
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="AWN90_RS04290"
                     /old_locus_tag="AWN90_04315"
     CDS             complement(11098..12261)
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020101983.1"
                     /locus_tag="AWN90_RS04290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_04315"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_067577870.1"
                     /transl_table=11
                     /translation="MSVADLGIPPGTGTPADATGASGIRRSKRLWVGSVPVGAGAPISV
                     QSMCTTTTADVDSTLQQIAELTAAGCEIVRVAVPSRDDAAALPRIVARSPIPVVADIHF
                     QPHYVFEAIDAGCAAVRVNPGNIKQFDDRVADIARRAAAAKVPIRIGVNAGSLDRRLLA
                     RHGGATPQALVESALWECSLFEEHGFTDIKISVKHHDPMTMVAAYRELAARCEYPLHLG
                     VTEAGPLMQGTIKSAVAFAILLHGGIGDTIRVSLSAPPVEEVKVGIGILESLGLRQRKL
                     EIVSCPGCGRLQVDLYNLTAKVEAAFADFPFPLRVAVMGCIVNGPGEARAADIGVSSGN
                     GKGQIFVRGEVVATVPEHRIVETLVEEAAKLAADTHTPSDSTPGVER"
     misc_feature    complement(11434..11436)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12258..14096)
                     /locus_tag="AWN90_RS04295"
                     /old_locus_tag="AWN90_04320"
     CDS             complement(12258..14096)
                     /EC_number="2.2.1.7"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF003933.0"
                     /locus_tag="AWN90_RS04295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_04320"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_253949877.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 9.4e-79,
                     bitscore: 262.4, seeds: 174, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAAPEYIDPTADLGGWPMLAEACSPAQLRRIPRDRLPELCTQI
                     REFLVTKVCATGGHLGVNLGVVELTVALHRVFDSPRDAIVFDIGHQIYVHKILTGRAAG
                     FEGLRQEGGLSGYACRAESPHDWVENSHASTALSYADGLADAFTIAGRTDRTVVTVIGD
                     GALTGGLAWEGLNNLAARPDRRIVLVLNDNGRSYDRTVGGIAKHLKDLRLGEGQVRSIF
                     EQLGLTYLGPIDGHDIDQLERTLRSAGEFGKTVVVHVVTEKGFGYPLAELDQADHMHGI
                     GVLDPRTGKPLSPTGQSWTSAFGDEIIRLAARRTDLVCVTAAMTQPVGLLRFSQTYPGR
                     MFDTGIAEQHAVCAAAGLAMGGLHPIVAMYSAFLGRAFDQVLFDVGLHHLPVTFVLDRA
                     GITGPDGPSHHGMWDTGLLGMVPGMRVAAPRDPARLRELLAEAVDHTGPSALRFPKSTV
                     GHDIPALSRIDDMDILHRSVGRSLDLLIVCAGVTAEQCLDAAAIVEAAGYGVTVVDPRW
                     VDPVGSPLLHLAARHRTVVTVEDACVTRGLGTSLIRCAAAMPEPIPIRPIGIAAEFLRQ
                     GARTDLLAASGISAGSIASTGLQALADRGDPKGGRS"
     misc_feature    complement(12783..12785)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(14108..15058)
                     /gene="ispH"
                     /gene_synonym="lytB"
                     /locus_tag="AWN90_RS04300"
                     /old_locus_tag="AWN90_04325"
     CDS             complement(14108..15058)
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /GO_process="GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ispH"
                     /gene_synonym="lytB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012392269.1"
                     /locus_tag="AWN90_RS04300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_04325"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_067577874.1"
                     /transl_table=11
                     /translation="MAARELVLASPRSLCAGVDRAVETVEAVLAQHGAPVYVRKQIVHN
                     VHVVAGLESKGVVFVDELDEVPDDSLVVFSAHGVSPRVHAEAARRRLRVIDATCPLVTK
                     VHSEAKRYATQGNTIVLIGHAGHEEVDGTMGEAPEQTVLVETVEDVAALTVPDPDRVVY
                     LTQTTLAVDDTAEVIAALLARFPRAVGPAGGDICYATTNRQAAVQQVAEQTDVVLVIGS
                     ANSSNSVRMVERVRRQGTPAYLIDDAAAIEPEWLAEARAVGISAGASAPQWLVDEVVAH
                     LVRLGATAVRELAVTTETMQFSLPQQASSTRTQLK"
     gene            complement(15060..16097)
                     /locus_tag="AWN90_RS04305"
                     /old_locus_tag="AWN90_04330"
     CDS             complement(15060..16097)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014987551.1"
                     /locus_tag="AWN90_RS04305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_04330"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_067577876.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.6e-56, bitscore:
                     188.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAIDAVGRRRAPEILKSVRVLIDTEYRTVVKSLPESLCRIGGYN
                     IGWWDASGTPTAESGKYLRPALAILSSAAMSDGSIDLVRDRAIAAAVAVELVHNFTQLH
                     DDIMDNDRIRRHRTSAWAQFGVGPAILAGDLFLFAATEVLSPYDHVVMEILGATLRELC
                     EGQMADLSFEQRHMVSLDECFRMSEGKTAALLGAACELGAWAAGVDAQRRAFMRKFGWE
                     VGRSCQLVDDLLGIFGDPEVTGKPVYADLIRRKKSLPVVAALNSDTAAGMELRQIYASS
                     RQLKRAELAHVARLIENAGGRRWAEDMARETRGAAGTFLASADPTEEAAADLLILADFI
                     MGRDH"
     misc_feature    complement(15810..15812)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(15984..15986)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    16410..16425
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.59"
                     /tool="antismash"
     misc_feature    16421..16434
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.16"
                     /tool="antismash"
     gene            complement(16916..>17305)
                     /locus_tag="AWN90_RS04310"
                     /old_locus_tag="AWN90_04335"
                     /pseudo=""
     CDS             complement(16916..>17305)
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611184.1"
                     /locus_tag="AWN90_RS04310"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_04335"
                     /product="DDE-type integrase/transposase/recombinase"
                     /pseudo=""
                     /transl_table=11
                     /translation="NQKYVGDITYLPLGDGRFLYLASVIDLYSHRLAGWSIADHMRTDL
                     ITDALRAAAATRGSLAGAILHTGTHRFESARHARLAVFRWITRYNTRRRHSTLGHTSPI
                     IYEQQAGTVLAAARQAVPTPLGEAP"
     gene            complement(17617..19179)
                     /locus_tag="AWN90_RS04315"
                     /old_locus_tag="AWN90_04340"
     CDS             complement(17617..19179)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033551.1"
                     /locus_tag="AWN90_RS04315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_04340"
                     /product="IS1182 family transposase"
                     /protein_id="WP_082870540.1"
                     /transl_table=11
                     /translation="MSLRPHGPAGIPARTAEAAWSSCPKGAPAMLIRDRLSELIGDEEF
                     LSWYPTDGRPSLSPAQLMLVSILQFAENLSDRQAADAVRLRLDWKYALGLELEDAVFDY
                     SVLSEFRARLGEHDRADRLLQVMLARLIGAGLLEGRGQQPTDATHVLAAVRRLSRLELA
                     GESVRAALQELAEADPDWLAPLVEPRWAKQYGRKVEIGKVPGGRSGIIDLAETIGRNGL
                     KLLTAVGTATAPPRLRDLPKVKILRRVWMHQYYWDPEGQLRWCEGTALPPASLRFDSPY
                     DPDAHYCVKRDTAWSGYRTHFTETCDEDLPHVVTHVATTIAPVQDGVLTETIHDDLAAQ
                     QLAPAEHIVNTAYITPARMERAQRVHGIKLLGPIPTDHSPQAKRGTGFDKSAFDVDFDQ
                     HTATCPQGTTSRQWTPTRINDSDYILVKFPTKTCRDCPQRAQCTTAVSGPRSLALLPHP
                     LHEIQIQARAEQATDEWKQRYAVRAGAESTISQNVRISGPRRSRYRGPRAGVGSARDRR
                     LRG"
     gene            complement(19409..20137)
                     /locus_tag="AWN90_RS42735"
     CDS             complement(19409..20137)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012394487.1"
                     /locus_tag="AWN90_RS42735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4389 domain-containing protein"
                     /protein_id="WP_082870541.1"
                     /transl_table=11
                     /translation="MQQKLAGYPIRVRGDLDPALSRWKWLIKWVLAIPHFVVLFFLAIA
                     YSIVTMVAFFAVLCTARYPRTLFEFNVGVMRWAWRVSFYSFVLGTDKYPPFSLSTDSDY
                     PADLEVDYPERLNRGLVLIKSWLLAIPHYLIIAAVGSEAAHMLSATDYGDWVNATAISL
                     LTILIATAEISLLFIGRYPIGIFEFTIGLNRWIWRVQTYAALMCDEYPPFRLDQGAREP
                     VCVMREIEAAEPTAAERGNK"
     misc_feature    complement(19613..19615)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(19964..19966)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(21144..21156)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.71"
                     /tool="antismash"
     misc_feature    21208..21221
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.95"
                     /tool="antismash"
     gene            complement(21276..>21698)
                     /locus_tag="AWN90_RS04320"
                     /old_locus_tag="AWN90_04345"
                     /pseudo=""
     CDS             complement(21276..>21698)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019047411.1"
                     /locus_tag="AWN90_RS04320"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_04345"
                     /product="ABC transporter permease"
                     /pseudo=""
                     /transl_table=11
                     /translation="VVGWRINGAIASAALAFGVILLFAFAMSWVGALTGLMSPSVEVAQ
                     SAGLIWLFPVTFVSSAFISAETLPGPLRTMAEWNPITAVSAAGRKLFDNGAPPSFVPPR
                     GWAADHCVEYSIGCSLASLVVAMPLAQLQYPKVANH"
     gene            complement(22024..22797)
                     /locus_tag="AWN90_RS04325"
                     /old_locus_tag="AWN90_04350"
     CDS             complement(22024..22797)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007620202.1"
                     /locus_tag="AWN90_RS04325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_04350"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_067577882.1"
                     /transl_table=11
                     /translation="MLLGKNTARTHDACGQFYTLIQVRVPGQHTSASRHPAVQARRAER
                     RRKLLAAGIEVFGDRGYANSSVTLLCHAAGLARAQFYEHFDNREDLLLAVYDMIQEQAR
                     HAVSQAVAEQADDVVARAHAAMTAFAESVGHDPRRARLVFVEVIGVSERAEQHRVQSRE
                     LWVRYIAEQIAHTRGADYCPPGGYTAAATGFIGALMALVHQWSLGSADMKLTDAVEVLT
                     HFLISLINPESMGATGANVVITLLAEGSATTSQSR"
     misc_feature    complement(22063..22065)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(22805..24886)
                     /locus_tag="AWN90_RS04330"
                     /old_locus_tag="AWN90_04355"
     CDS             complement(22805..24886)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014353187.1"
                     /locus_tag="AWN90_RS04330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWN90_04355"
                     /product="CocE/NonD family hydrolase"
                     /protein_id="WP_231951297.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 8.4e-06, bitscore:
                     23.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPKISMPRFMLKVVVFTAVALICVPFLSNATLARAADGFTGPDG
                     GSYAAAWTASVDGPQPFPDMTTDLSVPITMSDGTVLKADVYHPATGNRPAEGRFPVILQ
                     MQGYGKLVANLGQILLKIPGVEQVLLPWISSLNFPGSGLDGITDLTRQLDSGVLRLLAQ
                     DWALVHAGYTLVQVDMRGTGASEGKWQVFGDREKLDAKEVIDWAARQPWSDGKVGLTGT
                     SFTGISALEATAHTPEALRAIFAGVPSTDVFRDIAGAGGATGLGFLSFWLLGVDLVKNA
                     PDLESVLSGRFDPAQQLQWLKDRLADPFTMLDVLAGAYGSTAWDHLPPGTKAFLDPNSP
                     IRQGLKTDLSKVTMPTFVLDASFDIFGTTPMESFEKVPLPLEQKKLIMGDGYHLFSGVA
                     GFGHPGMPPRVDVLQRAWFDKWLRGTDNGIDKYSPLTVKRQGGGWETITQSPQAESDYR
                     RMYLTDAPSGTAGHAVADGSLSPRPNPAGVHDFSVAPSLLSLCSRDMARITGGATSVIV
                     ACTEDSRIWEHSGLAFTSGAVTAATQISGPIAVHLNVVHDAPDGYWVATVNDVAPDGQS
                     REISSGQLVSSLRKIDDAQSSRSPNGDYTIPVPFVDINQREPVIPGQPLTLDIALTPIE
                     AVLQPGHRLRVDVYASNGLKGVPTLPTLAASGLRPQTLRLDPATPSWVNIAVNNDIPE"
     misc_feature    complement(24404..24406)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(24900..24915)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.55"
                     /tool="antismash"
ORIGIN
        1 tcgcaggtaa cagtcccatg ccccggcgta tgtaccggtc tgctcggtcc gggcgaggac
       61 gatttcctcg ccctcggacc gatgcgtcag cacgatttcg ccgtctatca gcacgtagaa
      121 gtccttggcc gattcgcctt cgcgatacac cgcccctggc gcgaaagtcg ttgtcgtgct
      181 cgcccggctc agccacgtca gctgttcctc gtccaggctc tcgaagagga acagattccg
      241 cagcccggcc gggtcgtcga caggcttgcg catgatgtct tcccccgtct caactctgtg
      301 ccagataccg atgaaccagc atgaccgcca tgactccctc gcccaccgcc gatgacaccc
      361 gtttcgccga cccggcgcgg acgtcgccag ccacgaatac accgggaaca ttcgtctcca
      421 actgttgcgg cgggcgatcc agtgtccaac cgggtatagg accgccgtcc gccagcaagt
      481 cgggaccggt gagcaggaag ccccggtcgt cccgtaccaa cacgtcagcc agccagtcgg
      541 tgcctggctc agcaccgatg aacaggaaca ggcattctcc ggcgagctcc tcctcctcac
      601 ctgaagtgcc gttacgtacg aggattcgct cgagatgtgc gttgccgccg acctcgacca
      661 cctcggtgtt gagcttgacg cggatgttgg gggtgttggt gatctgttcg atcaggtagt
      721 gggacatgga cttgtgcagc gagtccgcgc gcacgattac ggccaccgag cgcgccgtcc
      781 gcgacagata caccgaggcc tgtcctgcgg agttcgcgcc gcccacgacg tggacgttca
      841 tccccttgca cagtgtcgcc tcggtcatcg cgaacccgta gtacacaccg cgaccggtga
      901 attcgcttat tccggctgcc gggtgcctgc gatagctcac cccggtcgcc accacgacgg
      961 tgtgcccgtc gatgatgctc ccgtccgtga aacgcactcg ccgcgcacct ccgcgcacct
     1021 cgagcttcac cgcattctgt gtcgtcacca attcggctcc gaacttcagc gcctgcctgc
     1081 gggcacgttc ggccagctgc gcacccgaca ccccgtccgg gaagccgaga tagttctcga
     1141 tccggctgct ctgccccgct tgtccgcccg gcgccgtgcg ttctatcaag accgtacgca
     1201 aaccttcgga ggcggcggtg agtgccgcac tcaaacccgc agggcccccg ccgatgacga
     1261 tcgcgtcgta gaagcccgtc gaaggcgagg tggtcaggcc gagcacttcg gccagctcgg
     1321 cattgccagg gcgcacgagt accttgccgg tggaggtaac caccaccggg caccggtcct
     1381 cttcgacccc ggcagcgcgc agcagccgat cgccctccgg ttcgttcacc aggtaccacc
     1441 ggtaggcgag ttgattgcga gccaggaatt cgcgcacctc cgagcatcgc gccgaccagc
     1501 ggctcccgat cactttggtc tgaacaaccg gtttgcgatc gtcggcgcac cacgattcga
     1561 gcaggccgtc tatcaccggg tacagcttct cctccgccgg atcccacggt ttgagcagat
     1621 aatggtcgag atcgacgata ttgatgccat cgatggcgac ggcggtttcc gcatatgcgg
     1681 tcaacaacac ccggcgagca agagggtgcg aatcgatcga tcgctcgaga aagtcgaggc
     1741 cgtccatctc cggcatccgg tagtcggcga tgatcaccgc gaccggctgt ccacgcaact
     1801 tgacttcgcg cagcacctcg agtccctggc ggcccgactc cgcacgaatg atctgatact
     1861 tgcgtccgta tcgctgccgc agatcgcgga cgaccgcgcg cgataccaca ggatcgtcgt
     1921 cgacactgag caccaccggt ttgaggccgg tgggcaccga gctgtacgtc tgttcccacc
     1981 cgactacgtc gatgggtgcc gtaccgctgg ttgttgtcgc catgagaatc gtactccgat
     2041 ccgcgctggt tcgtgttccg ccgattagcc gggatggtct tcgagcgctc tcggtcgccg
     2101 agcggccgtt ggctcagtca ggtcgtcgcg gccgcactgc ggtgtcgcaa gcagcccgtt
     2161 tgcgaagtcg gaaagcagac agtcgacgac ctctccggca tcgatccgat tcgtgccgat
     2221 accgccacgc ggcctgcgtt tggcccaacc ggtgacatac accccggcaa cgggcaagcc
     2281 acttgtatcg aggacgtggc cgtgttcatt gggaatgatt ccgtgctgct cgtcgaacgg
     2341 gacaccggga atcggcacgc tgcgatagcc gatcgagcgc agcaccggcg atccggcgat
     2401 cgattccggt ctacagtttg cggcggggtc gtcacccgca ccgaagccgt tgggccgcac
     2461 gcgaacgccc gcgacgtgac cactaccgaa cagttcgatc ggtgcgaccc gatagcggag
     2521 tacgatcctg cggtgccccg gtccaggaaa gcgtcgtgaa tattcttggg ctaacgccat
     2581 tttcatggcc gaagccgggt cgtcatcgag tgcccgcgcg gcggtctggc ccagttcgag
     2641 gtcaaccggg tcgatgacga cgtcgatgtt cggtaggtag ccgagctcca ggaactccga
     2701 ggtcgtgtac gcggcctcgg tcggcccgcg gcggccgagg atgacgacct cacgcacgtt
     2761 gctcgcgcgc agggcgtcga gcgcgtgatc ggcgatgtcg gtgcccggca atgtatccgg
     2821 atccgcggtc aggatgcgtg caacgtcgag cgcgacgttt ccgttgccga tgacgacgac
     2881 ggtgtcgccg gagagatcga agctcatgtc ggcgtagtcc gggttgccgg tgtaccagcc
     2941 gacgaattcg gccaccgaat gactgccggg aaggtcctca cccggaatgc cgaggctacg
     3001 gctggcgggt gccccggtcg cgtagacaac ggcatggtag cggcgtgcca gatcgtcgtg
     3061 cgtgatgtcc gtgccgatct gaacatcaag atgcaaccgg acacgctcgt cgtcgagcag
     3121 tgcagcgaag gtgttcgcca tcctcctggt acgtgggtga tcgggcgaca cgccgtatcg
     3181 cagcaatccc cacggcgcgg gctggcgctc gaagatatcg atctccgccg tgctgcggcg
     3241 aagcagctct tcggtggcgt agcacgccgc gggcccggac cctaccaccg ccacccacag
     3301 cggggcgcgc gcaggggacc ggcatggtac agcgcgggtc gccgcggcga gggctgctgt
     3361 gagcgggaag cgctgaaaat acgcggcatt gagttcggcg aagcgaccag cggcgggggg
     3421 cagttcgtcg tcgaagacga tggcgtccac cgggcacacg tctacacagg cgccgcagtc
     3481 gatgcaggaa tcgggatcga tgtacagcat atccgcggtt gcgaaggcgg gatcgtcggg
     3541 atgtgggcga atgcagtcga tcgggcattc gaatacacaa ctggcatcat tgcagcagga
     3601 ctgcgtgatc acatggggca taaccaccgc tccttgagca tgatcgggcg tactgcggga
     3661 gttcatccac catacgtagc tcgtacccgg ggtttcccaa ctgccttggg ggatatcgcg
     3721 gttgtcggat ttgcatgaga gggcagataa tttgtttgcg gtcggccctt gcgttggttt
     3781 ttggaacgcc gtgccttgcg gccgtgacga ttggcgggcg ttgaatatga gttgcgtggt
     3841 gtcggcgtct ttttccaaca gctccggtgc ggaatccgga aaacttagaa agtagagatg
     3901 acatgtcaga acagcgtatt ggctttcgca aatatgtcgg tgatctgatc gacagcgcga
     3961 aggatacgat ggatgcgagc aaggactgcg ccgacgatat attggatagg acctacggtg
     4021 tcgagcgcgg gttgcgaaat actgtgcgcg cggtcttcgg ccgtgacaaa aagccgtgaa
     4081 accgggacac ttgcacctcg ttgcggtcgt gatgggccat cttgccgccg atttcctggc
     4141 cgcccaggat cgcggcatgc cgacaccacg ggccatccgg cgcaggcagc gccgagccgt
     4201 tgccacccgc aaggcgctga atcggctcgg ccccttctac accaagctcg gccaggtcat
     4261 ggcgaccagg ccggacttcg tgaccaccat catgataacg gaactagaga aactgcagga
     4321 tcgctgctcg atcagcccgt tctcatcatt cgaaacagtg ctcaccgagg acctcggggc
     4381 gcaatggagg cagatgttcg ccgacgtgga cccggattca ccactgggtt cggcatcact
     4441 cgcgcaggtc taccgggtca ccacagctgc gggtcaggtc gcagcactga aggttcagcg
     4501 tcaaggcgta cgtgagacgt tcaccgcaga tatggcgatc acgatgcgaa tagcgaagct
     4561 gctgaacaga atcttcccaa ggatccacgc catgctcgac gtggaaacgg cgctacgtgt
     4621 cgtattcgat gcgatggaat ctgaattgga tttcaccatc gaggccaaca acatgaatga
     4681 ggcacgagcc atggtcgcca aatattcgtg cctctcgata ccgaaagtcc tacacgcgac
     4741 tcctcgggta ctgattcaga gtatggcgcc tgggatatcc attcgggaag ccgatcccac
     4801 cgctttcacc ggaagggagc gcgagcagat cggccgagat ctgctgagct tcatgtacaa
     4861 cgggtatttc gtgcaccggt tctttcacgc cgatccgcat ccaggcaata tcttcgtgca
     4921 tcccggacaa ggagcctggc tcctggattg ggggatggtc ggccgactcg accgccacct
     4981 gagctcggcg atgctgctgg tactcagcag catcgcccag aacgatggta tagccatggc
     5041 caaggcgtgg atggaactcg ggcatccgat gccatgggcc gatgttcgcg gcttcgctga
     5101 cgatatgagc ctgctggtgc ccaagttgtg ctcacgttcc atgggcgacc tgagtctcgg
     5161 cgtgacgctc accgcactgc tgcgggcagc agccaaacgc ggtatcaggt ccagtccgct
     5221 cgtcgccctg gtcggcaagt cgttcggcaa cattgaaggc tccgtcactt gcctgacccc
     5281 ggaactgtcc gtcgtcggcg tcttccaaga cacgctgacc gatgtgctgc gcggtatggc
     5341 gagtgatctg atctcgaagg agcagctcgg gcgctccgcc atcgacgtct atctcggcgg
     5401 gaccacattt ctcagccaga ccagggaaat cctggactcg gtgtccggtg ggcagttcgg
     5461 catccgggtc ggcatcgacg aaagaactgt attcaaggcc cagaccattg gcagccaggc
     5521 caagccgctc gtcctcggcg cgctggcggc gggtgcgatc gtatggctgc gcgggctgcg
     5581 tagagccggt tagcccggag ggcaccgttt tttggagaat cccatgttcg ataggactca
     5641 caccacggtc gagcgatcca ccctgcggcg ctgtggcgag tggattgtcc ggcaccgata
     5701 cctcgtcgtg atcggttggc tgctgtgtgc cattgccact gcgctggccg cgcatgccgt
     5761 cgggccgcgc tacgacgacg gcggcgcggt tcccggtacc gactcccgcg ttgctcagga
     5821 tctgctggct gcccggtttc cggtctatgc cgggtccagc ggtgtggtgg tcttccatgc
     5881 cacgaatgat cgtctgtcgg ccacgctggt ggatgacgcg gtgcgacgga tcgccggact
     5941 gccccacatc gtccgggtca tcgatccctt cgccgctgcc ggtgcgttga gcgaggacaa
     6001 gcggacaggc tacgccgccg tgcagtacga cacccgattc agcaccgggg attccgagcc
     6061 actgcaccgg ctgatcgacg caaccgcgac cgcgcgcgcc gccggtgtgc aggtcgaggt
     6121 cggcggcccg atcgcggacc tggccgggtt gcacgcaccc cgcacctcgg aggtactcgg
     6181 cgtcaccgcc gcgctggcga ttctgacgat cacgttcggc tcgctggtcg cggccgggct
     6241 gccggttctg accgcggtgg cggggctgct ggtcggcgtc gggacagccg agctggccag
     6301 ccgcctgctg ccgcagatgc ccgagcaatc cgtgccgctc gcggtcatga tcggactcgg
     6361 cgccgggatc gattacgcac tgctcatcgt gacccgattc cgcgagttcc tcgccgaagg
     6421 ggcggacgtg gcggccgctg tcaccgagtc gatggccacc gcgggtgaat cggtcctcgt
     6481 cgctgggctg acggtgacgg tgagcctgct agggctgtgg gtcacccggc tgccggtgat
     6541 cggtgcggtc ggcaccgcat gcgctatcgc ggtcggcgcc gcgttgctct ccgcgctcac
     6601 cctgctgccc gcagtgctgt cgatcatcgg gacagcggtg aaccggctgg cgataccggt
     6661 gaccaccgac cgtggcggcg cgggctgggc caggtggggc ggccgaatca gcaagtcgcc
     6721 gtggttcttc gtgattggat cggtggctac gctgctggta ctggccctgc cgtcggccgc
     6781 attgcggctc ggcatcgccg acgcgggggt ccagccgcag tcacagacgc agcgccgcgc
     6841 ctacgatctg atcgcgcgag acttcggtat cggcgccaac ggcccgctgc tgctggtcac
     6901 cgggttgacc ggggcccgac aggagggcac cgatctcgac cggctgagtg ccgcggtgcg
     6961 cgcggcaccg gacgtcgccc gggtagcccc ggtcgagatc gccccggacg gcagggccgc
     7021 ggtgctcacg gtcgttccgg cgcatgcgcc gtcctcaccg gcgactgaca acctggtaca
     7081 ccggctgcgc gacgtcacga tccccgcgag tggggtgtca ttgcgggtgt atatcggcgg
     7141 cgcgacggca tcgggcatcg acatgggcgc cactgttcgg tcgcggctgc tctggtttgt
     7201 cggcgccgtc gtcgcactga ccatcgtgct gctgacagtt ctgttccggt cggtgctcat
     7261 cccgctcaag gccgcgatct tgaatctgtt gtcggtcgga gccgcgtacg gcgctgtcgt
     7321 cgcggtcttc caatggggct ggggcgcgtc attgatcggg ctcgacggcc cggtaccggt
     7381 gtatccattc ttccctgcag tgatattcgc cctgctgttc ggactctcga tggactacga
     7441 ggtgttcctt ataacccgca tccacgaggc atatcgtggt ggtgcgggta ctttcggttc
     7501 ggtgatccag ggcaccgccg cgaccgcccg catcatcggc gccgcagcgc tgatcatgat
     7561 cgccgtgttc accgcgttcg tgctccaagc cgatccgacc gtcaagctgg ttggattcgg
     7621 tctcgcggtg gccgtgctac tggatgccac aattgtccgg ctcatgctgg tgcccgcggt
     7681 gttgtgcctg ctcggcgtgt atgcatggtg gtttcccacg ctgcggcgcg gtgccatggc
     7741 cggctgccgg aacagcaagt acggtcacct attctgccta ctggatcagg acaaggacgg
     7801 ctacctggac cgcggtgact tcgaagcaat agctggggcc gcgacgcggc tggccgaccc
     7861 acacctggcc cagaatattc gtaccggatt ccaggactgg tggcgacaac tgcccgccga
     7921 cggccacgac aagatcagtc tccctgattt tatcgacgca aattatcgcg ggctcgccgc
     7981 cgatcccagc tactacggca acggacccgg acaggtattc gaaatactgg ccgcgaccgt
     8041 ggccagtggc gatggcacca tcgacgaggg taattttgtg cggttgttcc gctgcttcgg
     8101 agtacccgac tcggcgattc gcaagggcta ccgcagaatc gatctggacc gcgatggcat
     8161 cattacgaaa tcagaattcg ccgccgcggt tcgagagtat ttcaccgcgt cgaaaggtgc
     8221 agtcgtcggc aattacatat tcggacccat ctgagccgac cgtccgggca gcgacgaggg
     8281 gtcgtcgagt tcgagcggac actcgcatat cgtatcaacg cgcgaccgga tggcagactt
     8341 cgccacgccg ccgaatcgcc cttgaagtcc cccgggggtt ccgtcggcgt gaagtctgtg
     8401 ctatcttcgc cccggttcag ttcctatcga aagcgttgac aatctggtcg tctcgtgaat
     8461 gtccgaaacc ggcagaatcg cagtcagctc cccagcggtg ctccagattt gttgtgaaag
     8521 tacaaatcgc ccggcaagat cgtgcggcca attttaggtg gtttacgact gacagttggt
     8581 atgcccgatc cgcacggatt tgggtaccga tccggggtca ttccggcacc gtcacactcg
     8641 gtggagcttg gaagtgccga cgatcgcgct ggtgagtatt gccatgtggt ttcctagacg
     8701 agcgcacgag gcctatacat ataccatacc gagaggtcta ttagagaggc cattttcgaa
     8761 ttcaaccctg atggaggcgc gatgcaagca caccgggcag aacagcaagg aagtggattg
     8821 tcggtaggtg cgagaataga attgcggcgc catcaattcg gactctctcg ccgcgtagtg
     8881 gcaaatctcg tcggccgcag tgaggaatgg ctacgcttgg tggagtcggg ccgccagtca
     8941 ttggatagta taagaataat agccagtttg gcggaggtgc tgggaataga gaacattgcc
     9001 gaattgatag aatggtcgac cggccgtcac gcaattaatc gcgacagcgg gcaggatcat
     9061 atattggagc tcttcaaaca tgcgatcgtc gatccgctcg acatcaacgc cgcggcatct
     9121 tcgccgaacg tctcgatcga agagctacgt cacgggctcg tccgttgcga ggagatctgg
     9181 cacagctcgg gggagcgcta ttctctggtg gcgcagctgc tgccatcgat cgttcgcgac
     9241 agcggcagat tgttctggac aaccatggat cctgcggtcg gcgagatagc gatccgcgcg
     9301 aaccatatga cgcggcgatt tctcaaccgt atgaactggc acaatctggc ggccatggtc
     9361 gccgaccgga gtatgtgtat ttctcgatgt ctcaagacgt cattatggac gacggcaagt
     9421 gcatggcatg tcggcaacgc aatgttacgc ctggcgttgc cgatagaggc acacgatatc
     9481 gcgactgccg ccatcaatac actcgacgaa acggtggacg acacgcggaa gcaactgatt
     9541 ctacgtggtg cgctgctcct cctggccgcc gaagccgcag caatgactca taatgtccgg
     9601 gaggccgatg agctgatcac gctggccaca cacctgtcga gagagctcga cgatgagcag
     9661 atggtcggcg atatcgcgtt cggcccgatg gctgttgggc tcgccaggat agaaatcgca
     9721 ctcctgcgag cggaattcag cgagatccct cgaatcgcgg ctcaagtaga ggtgcccgaa
     9781 gggtattcgg tgggcgatct cgcgcacttc cacatcgcac tcgcgtatgc cttcgcgcat
     9841 cgtaacgagg atgtggcggc ggcctattcg ctgtcacggg cagcggacct atgcccagag
     9901 gaaatccgtt acgacaagta cgcatgtgag acgatggagc agttgatcca tcgcgagaac
     9961 cgcctggttc ggcgggacat caccaaactc ctcgcccgca tcaccgcatc cacgtaatcc
    10021 cgcgggtgac gttgtcggcg acggcacgca gggcgtcctt gacagccatc gggaacgtgg
    10081 cccgatccag gacgccctgc gcccgttccc accgagtgcg gatcatctgc tggacctgtc
    10141 cgcgcgcgac gatgtcgaat atctcccgac aggtggcggc cccgctcgca tccaattccg
    10201 gattgccgac cagctcgtac agccgagccg attgcgccgg atccgcatgg cgtacagcga
    10261 acgccagcaa ggcggtgtgc ttgccctcac gcagatcgtc gaggctcgac gcgccggcac
    10321 cgtacacgcc ctccagatcg ttctgcagct ggaaggcgac gccgagcgga cccgcatacg
    10381 cgcggaggtc ctgttgtatc cggatgctgg cgtcggcgag cgcggcgccc atccgcaacg
    10441 ggcactcgaa ggtgtagctg gaggtcttgt accgtacgat ctccagtgct ttctccacgt
    10501 caccgcctga taggccgctt gtggcgagat ccagatattg cccgtagatg acatcggtcc
    10561 gcatggtgtc gaatatcggt atcaccgttg ccgtttgggc gggtgtgagc tgtgcggtgt
    10621 gcagcatttc gtcacaccac agcatgacga gatcaccgag cagaatcgcg gcgcgcatgc
    10681 cgaagcgatc tgcatcgggt cgtgtccggt accgctgaga cacgacccga tgcaccgtcg
    10741 gcctgtttcg ccgagtatca ctgttgtcga tgatgtcatc gtggacgagg acggcggtat
    10801 ggcacagctc caacgcggcg gccacctgga tcacgggtgt cggcacggcc gaatctcccc
    10861 ccgcggcaag ccatcccagc gccaccaggg tcgggcgtag ccgtttgccg cccgcgaaga
    10921 cgaagtcgtg cacgatgtcg gtgatttcac gcggcagccc gcgtttctcg agggaatgcg
    10981 cctgctgtcg caggaaccgg tcgagtatcc cgtcgacctg cttccggatc ccggccaaat
    11041 tgacgggggc cgaggtggtt tcggatccgg tcacggagca ccggccggag tccgcggtca
    11101 tcgctccact cccggtgtgg aatcggatgg ggtatgcgtg tctgcggcga gtttcgccgc
    11161 ctcctcgacc agggtttcga cgatgcgatg ttccgggacc gtggcgacga cctcaccgcg
    11221 gacgaagatc tgtcccttgc cgttgccgct ggatacgccg atatcggccg cgcgtgcctc
    11281 gccgggtccg ttaacgatgc agcccatgac cgcaacgcgg agggggaacg ggaagtccgc
    11341 gaacgccgcc tctaccttgg cagtgaggtt gtagagatcg acttgcagcc gcccacagcc
    11401 cgggcaggag acgatctcga gcttgcgctg tcgtaatccc agcgattcga gtatgccgat
    11461 gccgaccttg acctcctcca ccggcggtgc ggacagggag acccggatgg tgtcgccgat
    11521 ccctccgtgc agcaggatcg cgaaggccac cgccgatttg atcgtgccct gcatgagcgg
    11581 gccggcttcg gtgacaccga gatgcagcgg atattcgcac cgtgccgcca gctcacggta
    11641 ggcagcgacc atggtcatcg ggtcatgatg cttgacgctg atcttgatgt cggtgaaccc
    11701 atgttcttcg aacagcgagc actcccacag ggcggactcc accagtgcct gaggcgtcgc
    11761 gccgccatgt ctggccagta ggcgtctgtc cagcgaaccc gcgttcactc cgatccggat
    11821 cggcaccttc gcggccgccg cacgacgggc gatgtcggcg accctatcgt cgaactgctt
    11881 gatattcccc ggattcaccc ggaccgcggc acatccggca tcgatcgcct cgaaaacgta
    11941 gtgcggctgg aagtggatgt cggcgaccac cggaatggga gatctggcca cgatccgcgg
    12001 cagcgccgcc gcgtcatccc tggacgggac cgcgacacgg acgatctcgc aacccgcagc
    12061 cgtgagttcg gcgatctgct gcagcgtcga gtcgacgtca gcggtagtgg tcgtgcacat
    12121 cgactggacc gagatcggcg caccagcacc gaccggcacc gaaccgaccc acagtcgctt
    12181 cgagcgacgg ataccgctcg cacctgtcgc gtccgctggt gttccggtgc cgggcggaat
    12241 gccgagatct gcgacgctca tgatcgcccg cctttcgggt cgccgcggtc cgctagggct
    12301 tgcagccccg tcgaggcgat ggatcccgcg gatattccgg acgctgccag cagatccgtg
    12361 cgcgcccctt gccggaggaa ttccgccgct attccgatcg gcctgatcgg gatcggctcc
    12421 ggcatcgctg cggcgcagcg aatcaggctg gtgcccaagc cccgcgtgac acaggcatct
    12481 tcgacggtga cgaccgtgcg atgtcgcgcg gccagatgca gcagcggcga acctaccgga
    12541 tcgacccacc gcggatcgac gaccgtgacg ccgtacccgg cggcttccac gatcgcggcc
    12601 gcatcgagac actgttcggc ggtgacgcca gcacacacga tgagcagatc cagtgaccga
    12661 ccgacgctgc gatgcagaat atccatgtcg tcgatccgcg atagagccgg aatatcatgg
    12721 cccacagtcg atttggggaa tcgcagtgcg ctcgggcccg tgtggtcgac ggcttcggcc
    12781 agtaactcgc gcagccgcgc cggatcccgt ggggcggcaa ctcgcattcc gggtaccata
    12841 ccgagcaggc cagtatccca catgccgtga tgcgacgggc cgtctggacc ggtgattccg
    12901 gcccgatcca gcacaaaggt gaccggtagg tgatgtagtc cgacatcgaa caacacttga
    12961 tcgaatgccc tgccgaggaa agccgaatac atcgccacga ttggatggag cccacccatc
    13021 gccaatcccg ccgccgcgca taccgcatgc tgttcggcga ttccggtatc gaacattcgg
    13081 ccggggtatg tctgcgagaa tcttagaaga cctaccggtt gggtcatggc ggcggtcacg
    13141 cacaccagat cggtgcggcg cgcggccagg cggataattt cgtctccgaa cgccgatgtc
    13201 caagactggc cggtcggaga gagcggcttc ccggttcgcg ggtctagcac gccgatgccg
    13261 tgcatgtgat cggcttgatc gagttccgcg agcgggtaac cgaatccctt ctcggtcacc
    13321 acgtggacca ccacggtctt gccgaattcg cccgcgctgc gcaatgtccg ttcgagctgg
    13381 tcgatgtcgt gcccgtcgat cggccccagg taggtgaggc ccagttgctc gaagatcgac
    13441 cgcacctggc cctcgccgag tctcaggtcc ttcagatgct tcgcgatacc gccgactgtg
    13501 cggtcatagg atcgcccgtt gtcgttgagc accaacacga tgcggcgatc cgggcgtgcc
    13561 gcgaggttgt tcagcccttc ccaggccaag ccaccggtca aggcgccgtc accgatcacg
    13621 gtgacaacgg tgcggtcggt ccgcccggcg atagtgaacg catccgcgag accgtcggcg
    13681 taggacagcg cggtggacgc atgcgagttc tccacccagt cgtgcggtga ttcggcccga
    13741 caggcgtatc ccgacagccc gccctcctgt cggagaccct cgaaaccggc ggcgcggccg
    13801 gtcaggatct tgtggacgta tatctggtgt ccgatatcga aaacgatggc atcgcgcgga
    13861 gaatcgaaca cccggtgcag cgcgacggtc agctcgacaa cgccgaggtt caccccgagg
    13921 tgaccacccg tcgcacagac cttcgtcacc agaaattctc tgatctgtgt acacaactca
    13981 ggtagtcggt cgcggggtat gcgccgtagc tgtgcgggtg aacaggcttc ggcgagcatc
    14041 ggccagccgc cgaggtctgc ggtcgggtcg atatattctg gggcagcggt agtcatcgaa
    14101 cttctcctca cttcaactgc gttcgcgtgc tggaggcctg ctgtgggagg ctgaactgca
    14161 tcgtctcggt ggtgacggcc agttcgcgca ccgccgtggc gccgagccgg accaggtgcg
    14221 cgacgacctc gtcgaccagc cactgcggcg ccgacgctcc cgccgagatc ccgaccgccc
    14281 gcgcctcggc cagccattcg ggttcgatgg cggccgcgtc gtcgatcagg taggcgggtg
    14341 tgccttgcct gcgtacccgc tcgaccatcc gcaccgaatt cgacgagttc gccgagccga
    14401 tcaccagcac gacatccgtc tgttcggcga cctgctgcac cgcggcctgc cggttggtcg
    14461 tcgcgtaaca gatatcaccc cccgccgggc cgaccgcacg cgggaaacgt gccagcagcg
    14521 cggctatcac ctcggcggtg tcgtcgacgg caagggtggt ctgggtcagg tagaccaccc
    14581 gatcggggtc gggcacagtc agcgccgcga cgtcctcgac ggtttcgaca aggacggtct
    14641 gttcgggtgc ctcgcccatc gtgccatcga cttcctcgtg cccggcatga ccgatcagca
    14701 cgatggtgtt gccctgggtg gcatagcgtt tggcttcgga gtgcaccttg gtgaccagcg
    14761 gacaggtggc gtcgatcacc cgcagccgcc gtcgtgcggc ctcggcgtgc acccggggcg
    14821 acaccccatg cgcggagaac accaccagcg agtcatcggg aacctcgtcg agttcgtcga
    14881 caaagacgac gcccttgctc tcgagaccgg cgacgacgtg cacgttgtgc acgatctgtt
    14941 tgcggacgta aacgggcgca ccgtgttggg cgagcaccgc ctctaccgtc tcgacggcac
    15001 ggtccacacc tgcacacaac gaccgcggtg acgccagcac caactcccgg gcggccatct
    15061 caatgatccc ggcccatgat gaagtctgcg agaataagca ggtccgcggc agcttcctcg
    15121 gtgggatcag ccgacgccag gaatgtgcct gccgcgccac gggtttcccg tgccatgtcc
    15181 tccgcccaac gccgtccgcc cgcgttctcg atcagccgcg cgacgtgtgc caattcggct
    15241 cgcttcagct gccgactgct cgcataaatc tgccgcaact ccatcccggc cgcagtatct
    15301 gaattcaaag cggctaccac cggcagagat ttctttcgcc ggatcaggtc cgcatagaca
    15361 ggtttcccgg tgacttctgg atcgccgaat atgcccagca agtcatcgac cagctgacag
    15421 gaccgcccga cctcccagcc gaactttcgc atgaatgccc ggcgctgggc atccaccccc
    15481 gcggcccagg cgcccagctc acaggcggcg ccgagcaacg cggcggtttt cccttctgac
    15541 attcggaaac attcgtcgag cgacaccatg tgccgttgct cgaacgacag atccgccatc
    15601 tgcccttcgc acagctcacg cagggttgcg ccgaggattt ccatcaccac atggtcgtac
    15661 ggggagagca cctcggtcgc cgcgaacaag aacaggtcac ccgccagaat ggccggtccg
    15721 acgccgaatt gcgcccacgc cgacgtccga tgacgtcgta tccgatcatt gtccatgata
    15781 tcgtcgtgca gctgggtgaa attgtgcact aattccaccg ctaccgcggc cgcgatcgct
    15841 ctgtcacgca ctaggtcgat cgatccgtcc gacatggccg cagacgacag gatcgccagc
    15901 gcaggacgaa gatatttgcc cgactctgct gtcggggttc ctgaggcgtc ccaccacccg
    15961 atattatatc caccgatccg gcataacgac tcgggcaaac tcttcacaac cgtgcggtat
    16021 tccgtatcta tgagaacgcg gacgcttttc aagatctccg gcgcgcgtct ccgccccacg
    16081 gcatcgatag cagtcatcac aaaatcatcc ttcctcggcg tccacgttcc ggatctcgat
    16141 ctcacccttg cgaatcccag gcaggcaccg ccactctcga tacattcccc ggaccgggtg
    16201 ttcacgggtg aggtcaccgt aaggggatat aaaatcgaaa tacgcaactg tccggtccac
    16261 cgatacgaat cggatcggcg cacaccaaga agccgatcga gcttcgggcc aaaacctagg
    16321 atgctcacca tcccagaaat atttgtccgg cgctccgcgc gggcgaacgc cgtcgaacga
    16381 tcagatgtta tcgatcggtc agttgtcgac tgagatattt ttgacgccgg tcaaggcgcg
    16441 gagacttgga aacatcgaaa tattcggttg gacaccgccg gtcggcgttg gagcgggtca
    16501 ccaaatcgat gggggtacac tgtggtcgat ggcgctcgat gcgaccgtcg tgtgcgatcc
    16561 cacgacgacc cgacaggtcc tgtgtgacga tcgagtcttc gataaggggg gagtttttcg
    16621 atcggatagg acaagtactg ggggacggat tggggacctg tccctaaagt cggcatcgtc
    16681 gacagcgacg gcttgcccag ccggctttcc ataccaaacg tgtatctgtc tacgtggaac
    16741 agatgacgga tgaaatcaac tcggtgctga gtggctggcg cgaccgggag gtgctcgata
    16801 tgctgagtga gaccagggcg atagccccga aggtactggt catcccgata tttgccgatg
    16861 ttgtaccagt tgctgtgcgc cagcagacca tatcggatct agccccgata cccggtcagg
    16921 gcgcttcccc caggggtgtg ggcaccgctt gtcgtgctgc ggccagtact gtaccggcct
    16981 gttgctcgta gatgatcggg ctggtgtgcc cgagggtcga gtgcctcctt ctcgtgttgt
    17041 atcgagtgat ccaccggaac accgccaggc gggcgtggcg ggcggattcg aaacggtggg
    17101 tgcctgtgtg cagaatggcc ccggccaggc tgccgcgggt cgcggcagcg gcccggagtg
    17161 cgtcggtgat gaggtcggtg cgcatgtggt cggcgatcga ccagccggcc agccggtgcg
    17221 agtacagatc gatcaccgac gccagataga ggaaccggcc gtcacccaac ggcaggtaag
    17281 taatgtcgcc gacgtatttc tggttcgttc gccgacgcgg tcgcggcgct cgcgggagcg
    17341 ggcgcggcga tggtgtcgcg gtggccgggc atcgccacgg tgtcgccgtg gtggctggcc
    17401 gcggcggcct cgggtggccg gttgctggtc cccgcgtggc cctgaccggg ttgcaacacg
    17461 agtccgctct gccgaaatcg gttggggtgc ggcattttcg gcgggtctat gtgttgacga
    17521 tccgaaggag gtgccgacga ctgatgtcgc aggccgacca tgagaacaag gcccgcctgg
    17581 agcgggccag agcgatcggg ctgttccgct acatgctcat ccgcgaagcc gccgatccct
    17641 cgctgacccc acgccagcgc ggggcccccg gtaacgggat ctgcgcgggc cactgatgcg
    17701 tacgttctgt gagatcgtgg attccgcgcc ggctcggacg gcatagcgct gcttccattc
    17761 atcggtggcc tgttcggcgc gagcctgtat ctggatctcg tgcagggggt gcggcaacag
    17821 tgccagggat cggggaccgc tgacagcggt ggtgcactgg gcgcgctgcg ggcagtcccg
    17881 gcaggtcttc gtggggaact tgaccaggat gtagtcgctg tcgttgatcc gtgtgggtgt
    17941 ccattggcgg ctggtggttc cttgcggaca agtagcggtg tgctggtcga agtccacatc
    18001 gaaggcggac ttgtcgaatc cggtgcctcg cttggcttgc gggctgtggt cggtagggat
    18061 cgggccgagc agcttgatgc cgtgaacccg ctgggcgcgc tccattcggg cgggagtgat
    18121 gtaggcggtg ttcacgatat gctcggccgg agccagctgt tgggcggcca gatcatcgtg
    18181 gatggtctcg gtcagcactc cgtcctggac aggggcgatc gtggtggcca cgtgcgtcac
    18241 cacatgcggc aggtcctcat cgcaggtctc ggtgaagtgg gtccggtagc cgctccaggc
    18301 ggtgtcgcgc ttgacgcagt agtgggcgtc gggatcgtac ggagagtcga accgcagcga
    18361 ggccggcggc aacgccgtgc cctcacacca gcgcaattgc ccctcggggt cccagtagta
    18421 ctggtgcatc catacccgac gtaggatctt caccttcggc aggtcccgca accgcggtgg
    18481 cgcggtagcc gtccccacgg cggtgagcag cttcagtccg ttcctgccta tagtctcggc
    18541 caggtcgatg atgccgctgc gcccgccggg aactttgccg atctccacct tccggccgta
    18601 ctgtttggcc caccggggtt cgaccagtgg tgcaagccag tccgggtcgg cctcggccaa
    18661 ttcctgcagg gccgcccgga cactctcgcc cgccagctcc agacggctca gccgccgtac
    18721 cgcggccagt acatgagtgg cgtcggtggg ttgctggccc cggccctcga gcagtccggc
    18781 cccgatcaga cgcgccagca tcacctgcag gagtcgatcg gcccggtcgt gttcaccgag
    18841 ccgggcacgg aactcgctga gtaccgagta atcgaacacg gcgtcctcca actccaggcc
    18901 cagcgcgtac ttccagtcca gccgcaaccg gaccgcatcg gcagcctggc ggtcgctgag
    18961 gttctcggcg aactgcagaa tgctcaccag catcaactgt gccggcgaaa gcgagggtcg
    19021 gccatcggtg ggataccagc tcaggaactc ctcatcaccg atcaactcac tcaaccgatc
    19081 ccggatcaac attgccggcg cacccttcgg gcagctactc cacgccgctt ccgccgtcct
    19141 ggccggaatc ccagcaggac catgcggacg tagtgacatc actcctcacc ttctggcaca
    19201 gattctcccc cgacgccagc aagccaaccc ccggaacaac gacctcctac aacatcacca
    19261 acagcgtcac gatattgagg ctggcgcctg gctgctgtcc ttcaggcgca gcgtcgggtc
    19321 gttgcgcagg atgggtctgc tggatcgagg tgcccgcaat gcgctggacg ggctgtgtcc
    19381 ggcggccacg cccaaacaga tctatggact atttattgcc cctctcggca gcagttggct
    19441 ctgcggcctc gatctctcgc attacgcata ccggctcacg cgctccttga tcgagtcgaa
    19501 atggcggata ttcatcacac atcaatgccg catacgtttg cactcgccag atccaacgat
    19561 taaggccgat tgtaaattcg aatatcccaa taggataacg gcctataaaa agtaaggaaa
    19621 tctcggctgt ggcaatcaag atcgtcagaa gcgatatggc agtcgcattg acccaatcgc
    19681 cgtagtcggt tgctgagagc atatgagcgg cctcgctccc aacagcggct attatcaagt
    19741 agtgaggtat tgccaatagc cacgacttta tcaacaccaa accgcgattg agtcgctccg
    19801 gatagtcgac ctccaagtcg gctggatagt cagagtcagt tgagaggctg aaaggaggat
    19861 acttatcggt gcccaggaca aacgaataga acgagacgcg ccatgcccat cgcatcaccc
    19921 cgacgttgaa ctcgaagaga gttcgtggat agcgtgcggt gcataagact gcaaagaatg
    19981 ccaccatcgt gacgatcgaa tacgcgatgg ccaggaagaa tagcacaacg aaatgcggaa
    20041 tggccagcac ccatttaatc agccacttcc agcgcgacaa tgcggggtcc agatcacctc
    20101 ggacccgaat agggtagcca gccaactttt gctgcatgta aggctccttc tactcaattc
    20161 gaattctgac ctgttagtcg aactatcgaa gatcaagatt cacgtagttc aaaagattcc
    20221 gaacgtccgg attcggatcg tccgatcctg gttgattgtc tgcgaccggc gataatatcg
    20281 ggggcatcta tgtcatttct cagcttcctg gcatatcgcg gcgattgcaa catcgcctga
    20341 cgtgtcgacg gaaccctcat ctagctgacc gagattatgg atcaatagag ggccgcaatg
    20401 tcgatggaaa taatgtagaa gtcacgagac cgcttctcgt cactggtaat ccctaccgac
    20461 cgtaagaggc agatctgatc agatgcacat atattgctgg aaatctgcac actcgatccg
    20521 cgctcacccg gagagcttga taacagagcg acagagcaga tggcagaatc taggcggcga
    20581 tcgaagcgct gtccccttgc cgatattctc caccgatgca gggtgcggtc gtaagcgagt
    20641 agtagctccg ctagtgagct ttaatgggtg attccatggg tgtgactgcg ggaaccggtt
    20701 gtcacgttaa agcctttgag gtgaggcatc cgcagggcgg tggtttcacc gttgagcggc
    20761 tgcgtgtgag cctgcgtttg gtgcaacgct gacaccacgc cgacgtggcg gtgatgcgac
    20821 gggggctgcc tcgaaatgcc tggtgtcgcc gccaattccg accgactcat acctatctct
    20881 atcagatatt tagttcacat ctcaaccctc catgttcgta atgctcacgt gattctcgaa
    20941 tcaacgcgga tcatacgctg ataatcgtgt gagacctgat aggtgccgca ataattacat
    21001 ttaccaacgg tttgcgatgg gttaatttct gatgcggcgc ccgccattca gccaagtgaa
    21061 cgatgcaact atagacagaa cagtggttgc tgtcaactgc aatccgggtt tgatacattt
    21121 ccgcggttca cgatgctccg gatgtgacaa agtcgcggct accttgcagt agtcatcgtc
    21181 tctaatgtga gtaccacgat aagtttgcat acgttggttt ccggatcgcc gcattcattc
    21241 cgaacaatgt ttcatgccgc cgtttgttgt gtacctcagt ggttggctac cttggggtac
    21301 tgcagctgcg ccagcggcat cgcgaccacc agactcgcca gcgagcagcc gatcgagtat
    21361 tcgacgcagt ggtcggctgc ccagccgcgc ggcggcacga acgacggtgg cgccccgttg
    21421 tcgaacagtt tccgaccggc ggcggatacc gcggtgattg gattccattc ggccatcgtg
    21481 cgcagcggcc cgggcagcgt ctccgcggag atgaacgccg aggagacgaa ggtgaccggg
    21541 aacagccaga tcaggcccgc gctctgggcc acctcaacgc tcggcgacat cagcccggtc
    21601 agcgccccca cccacgacat cgcgaacgcg aacagcagga tcacgccgaa tgccagtgcg
    21661 gcggaggcga ttgcgccgtt gatgcgccag cccaccacac accgacgacg gcatcgtacg
    21721 agcgcttggc tcagagccgt cccgtgccga catgtgttca gcagatcagc gatgctgaca
    21781 attccacgat aggctttgtt ttcaagcgtg gatgtagccc attgaccttg gcgaagtaag
    21841 cagtcccgcc caggccagca tcgatatcgg ccgatgcgaa cgatgttctg tcctgtccga
    21901 ggatgactgt tgtgatgcct tgtcttcgga atacgcgaac agatgcctcc acatagaaga
    21961 tctgcgggca tacggccgac cgtttgtcca cgaactggtc gtgtagaggt gtcgggtggg
    22021 atgttatctg gactggcttg tcgtggcgga gccctcggcg agtaacgtga ttaccacgtt
    22081 tgccccagtg gcgcccatgc tttcgggatt gattaggctg atcaggaagt gggtcagtac
    22141 ctcgaccgcg tcggtgagtt tcatgtcagc gctaccgagg ctccattggt ggacgagtgc
    22201 catgagagcg ccgatgaagc cagttgctgc ggctgtgtat ccgccgggcg gacagtaatc
    22261 agctccgcgg gtgtgcgcta tctgttctgc gatgtaccgg acccagagtt ctcgtgattg
    22321 cacgcggtgt tgttcggctc gttcgctgac gccgatgact tcgacgaaga ctaggcgtgc
    22381 tcggcggggg tcgtggccga cggattccgc gaaggcggtc atcgcggcgt gggcgcgggc
    22441 cacgacatcg tcggcctgtt cggcgacggc ctggctgacg gcgtgccggg cttgttcttg
    22501 gatcatgtcg tagacggcga gcagcagatc ttcacgattg tcgaagtgct cgtagaattg
    22561 tgcgcgtgcg agcccagcgg cgtgacagag cagggtgacc gagctgttgg cgtatccgcg
    22621 gtcaccgaag acctcgatgc cggcggccag gagtttgcgg cgtcgttcgg ctcggcgggc
    22681 ttggacggcg gggtggcggc tggccgatgt gtgctggccg gggactctca cctggatcag
    22741 cgtatagaac tgcccgcacg cgtcatgcgt gcgggcagtg ttctttccga ggagcactcg
    22801 cggcctattc cgggatgtcg ttgttcacgg cgatgttgac ccagctgggt gtggccgggt
    22861 ccagccgcag ggtctgcggc cgcagaccgc tggcagccag tgtcggcagt gtcgggacgc
    22921 ctttgagtcc gttgctggcg tagacgtcga cgcgcagcct gtgaccgggt tgcaggaccg
    22981 cctcgatagg ggtgagcgcg atgtcgaggg tgagcggctg tccaggaatc accggttccc
    23041 gctggttgat gtcgacgaat gggacgggga tggtgtagtc cccgttgggt gagcggctgc
    23101 tctgcgcgtc gtcgatcttg cgcagtgagg agaccagctg gccgctgctg atttcgcgtg
    23161 attgcccgtc gggtgcgacg tcgttgactg tggccaccca gtacccgtcc ggggcatcgt
    23221 gcacgacgtt gaggtgcacc gcgataggtc cggagatctg cgtggccgcg gtgaccgcgc
    23281 cgctggtgaa agccagaccg ctgtgctccc agatccgtga gtcctcggtg catgccacga
    23341 tcactgacgt cgctccgccg gtgatgcgcg ccatgtcgcg tgagcacagg ctgagcaagc
    23401 tcggtgccac cgaaaagtcg tgcaccccgg ccggattcgg tcgtggcgac aaactaccgt
    23461 cagcgaccgc gtgaccggct gtgccggagg gcgcgtcggt gagatacatc ctgcggtagt
    23521 cggactccgc ttgcggagat tgggtgatgg tttcccagcc gccaccttgc cgtttcaccg
    23581 tgagcggact gtatttgtcg atgccgttgt cggtcccgcg gagccacttg tcgaaccacg
    23641 cccgctgcag cacatccacc cggggcggca tccccgggtg tccgaatcca gcgactccgg
    23701 aaaacaagtg atacccgtcg cccatgatga gcttcttctg ctccaggggc aacggcacct
    23761 tctcgaagct ttccatcggt gtggtaccga agatgtcgaa cgacgcatcc aggacgaacg
    23821 tcggcatcgt caccttgctc aggtcggtct tcaacccttg gcggattggg gaattggggt
    23881 cgaggaaagc ctttgtgccc ggcggcaaat ggtcccatgc tgtcgacccg taagcgccgg
    23941 cgagaacatc caacattgtg aacgggtcgg ctaggcggtc cttcaaccat tgcaactgtt
    24001 gcgccggatc gaatcggccc gacagtaccg attccaggtc tggcgcgttc ttcaccagat
    24061 cgacaccaag caaccagaac gataggaaac ccaaaccggt ggcaccgccc gccccggcga
    24121 tgtcacggaa gacatccgtg ctcggcacac cagcgaaaat cgcgcgcagc gcctcgggtg
    24181 tgtgtgcggt cgcttccagc gcggagatac cggtgaacga cgtgcccgtg agaccgacct
    24241 tgccgtcgct ccacggctgc cgcgcggccc agtcgatcac ctctttggcg tcgagcttct
    24301 cgcgatcgcc gaagacctgc catttgcctt ccgaagcgcc ggtgccgcgc atgtcgactt
    24361 gcacgagcgt gtaccccgcg tgcaccaggg cccagtcctg tgctaagagc cgcagcactc
    24421 cggagtccag ctgccgggtc agatcggtga tgccgtccag cccgctgccc ggaaagttca
    24481 atgaggagat ccacggcagc aaaacctgct cgacaccagg gattttcagg agaatctggc
    24541 cgagattcgc tacaagtttg ccgtaacctt gcatctgcag gatcactggg aagcgaccct
    24601 cagcaggccg gttcccggtc gctggatgat acacatccgc tttcagaacc gtgccgtcgc
    24661 tcatggtgat aggcaccgac aggtcggtag tcatatccgg aaacggctgt ggaccatcta
    24721 ccgaagcggt ccacgctgca gcatacgacc cgccatccgg cccggtaaaa ccatcagccg
    24781 cgcgcgcgag tgtcgcattc gacagaaacg ggacacatat cagcgccacc gctgtgaata
    24841 ccacgacctt cagcatgaat cgtggcatcg agatcttggg cctcattgca ctcctcgaat
    24901 gtgagtcagc taacacgcaa cacgggaatt ggcatttccg agatgttgcc aactgatgcg
    24961 acaacaccac aagataatcg tcaacatact ttagacagat gtgtctaagg tgtcaacggt
    25021 gaaccgctat ggtcagtccg gggcttatcg gtacgacagc caggccgttt gctgggctgg
    25081 tttgatcaac acaattcggc tgaatcaccg caggccaccc accccaatcc gacaacgccg
    25141 ccgtcctggg ttccgagcga aacacgagag ggtgatggac cgccgcacac gccccggccg
    25201 cagggatccg acttcacgct ggtgaccggc gcggcaagcg gattcggcga ggcccacagt
    25261 cgggccttct ccgctgggtc cgcgacggcg cttggacggt gctgggacaa cggaactagc
    25321 gggcgccgat cgcgccgccg aagcattgcg ccagcccgat aacgcgagca ggacggacag
    25381 gagcagggct gcgatttgcg tgatagcaac gctagccgct ggctacttgc cttggggttc
    25441 tcgatgggcg gtggtcggct atttctgacc ggggagaggg ccgagtggta gtccgactat
    25501 gcctgcgacc gccgcgatgt actgctcgaa ttgcgtcagg atgttcttgg cgtcttggaa
    25561 tgtggtgagc tggtcggtgg tggtgcagcc gaccggcgtc ggtgcgccct cggtgaaacg
    25621 gttgtccagc cagttcaatg ccgatggctg cccccatact gccagcagca tatgttcgct
    25681 gagatggtcg cgcacgtatt ggacgggcgc gccgccggcg caatagttat gtaccatcgt
    25741 gtcggtgctt tccatcggaa cggcggtatc cagcgccgct tggtagacgt agaggggtgc
    25801 ggtcactcta gggttgttgc ggccgagggt cgcatcgtcg aaggtctcct tgacgtctgg
    25861 taactccatg aattccttca ccggaatcgt gaggtattgc tgatagttgt cgaagagttc
    25921 cgccacgacg ttcaggacga ggcatcgtga tcgaatccgc tccatcaccc gcagtccttg
    25981 tggagtcaga tgcgagtcga gggcgtctct gaatttcgga tatgcagccg ccaaggaaga
    26041 gatgccaatg ccgacaagac cggattcccc ggtccccacc agtggaagca gggcacg
//
