LOCUS       NZ_JTKO01000010        22053 bp    DNA     linear   CON 11-APR-2024
DEFINITION  Staphylococcus pseudintermedius strain 2001-08-299-1 contig_10,
            whole genome shotgun sequence.
ACCESSION   NZ_JTKO01000010
VERSION     NZ_JTKO01000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Staphylococcus pseudintermedius
  ORGANISM  Staphylococcus pseudintermedius
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus; Staphylococcus intermedius group.
REFERENCE   1  (bases 1 to 269712)
  AUTHORS   de Vries,L.E., Hasman,H., Jurado Rabadan,S. and Agerso,Y.
  TITLE     Sequence-Based Characterization of Tn5801-Like Genomic Islands in
            Tetracycline-Resistant Staphylococcus pseudintermedius and Other
            Gram-positive Bacteria from Humans and Animals
  JOURNAL   Front Microbiol 7, 576 (2016)
   PUBMED   27199912
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 269712)
  AUTHORS   de Vries,L.E. and Agersoe,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-DEC-2014) Department of Technology, University College
            Metropolitan, Sigurdsgade 26, Copenhagen 2200, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: SEP-2014
            Assembly Method                   :: CLC NGS Cell v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 20.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001622945.1-RS_2024_04_11
            Annotation Date                   :: 04/11/2024 12:27:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,368
            CDSs (total)                      :: 2,296
            Genes (coding)                    :: 2,259
            CDSs (with protein)               :: 2,259
            Genes (RNA)                       :: 72
            rRNAs                             :: 5, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1 (5S, 16S)
            partial rRNAs                     :: 1, 4 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 37
            CDSs (without protein)            :: 37
            Pseudo Genes (ambiguous residues) :: 0 of 37
            Pseudo Genes (frameshifted)       :: 13 of 37
            Pseudo Genes (incomplete)         :: 26 of 37
            Pseudo Genes (internal stop)      :: 7 of 37
            Pseudo Genes (multiple problems)  :: 9 of 37
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:20:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3811
            Orig. end                         :: 25864
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JTKO01000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22053
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..22053
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22053
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12053](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12053
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    complement(310..325)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            687..1244
                     /gene="pdxT"
                     /locus_tag="NO87_RS08730"
                     /old_locus_tag="NO87_08730"
     CDS             687..1244
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /GO_function="GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /GO_process="GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="pdxT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614783.1"
                     /locus_tag="NO87_RS08730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08730"
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="WP_014614783.1"
                     /transl_table=11
                     /translation="MKIGVLALQGAVREHIRHIELAGHEGVAIKKVEQLEEIDGLIIPG
                     GESTTLRRLMNLYGFKEALRASQLPMFGTCAGLIVLAKDIVGEEGYLQKLDITVERNSF
                     GRQVDSFESELHIKGIDQPIEGVFIRAPHIQSTEAAVDVLGTIDDKIIAVQQGRYLGVS
                     FHPELTDDYRMTQYFIEHVMQQ"
     gene            complement(1387..2145)
                     /locus_tag="NO87_RS08735"
                     /old_locus_tag="NO87_08735"
     CDS             complement(1387..2145)
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614782.1"
                     /locus_tag="NO87_RS08735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08735"
                     /product="trypsin-like serine protease"
                     /protein_id="WP_063284841.1"
                     /transl_table=11
                     /translation="MKKSFLKFSSTFLLLTTIGMTGTNAANVWGAEEGTKILVEDIQND
                     PLAKRTAIFQGPKGLPCTTTMLTSNFGLTAAHCGDGFLEGSVGTVYPAQSGLSTPFGSM
                     SISLFNPYNDKDIAFIYGQDSGKSKDYIHYQRDFAQTEIKLQGFTDDELKKMVGKKVYS
                     YGYPYNYHAHKQYRFTGEITFANSDFIKTNLPAYGGQSGSSVFLEDNDQLVGILVKGGD
                     DDKNAILEPITKDIARWYKGKKDILENPVQ"
     misc_feature    complement(2275..2288)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.69"
                     /tool="antismash"
     gene            complement(2628..3833)
                     /locus_tag="NO87_RS08740"
                     /old_locus_tag="NO87_08740"
     CDS             complement(2628..3833)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020363115.1"
                     /locus_tag="NO87_RS08740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08740"
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="WP_014614780.1"
                     /transl_table=11
                     /translation="MHILIGVIGIGVFLALAFIGSSDKKGIRWKYIGIMFVIQLILAYA
                     LLKTKIGITIVGGIATGFGYLLKQAGVGIDFVFGGLVNNGQMSFFLSVLLPIVFISALI
                     GILQYTKILPLIINILGFLISKINGMGRLESYNAVAAAILGQSEVFISLKKQLPYITKQ
                     RLYTLTASAMSTVSASIIGAYFTLVQPKYVVTAVVLNLLGGFIIASIINPYKVDEEEDK
                     LLLEEEKKKQSFFEMLGEYILDGFKVAVIVGAMLIGYIALISLLNGLVGGLISLISGGA
                     LDWNFQTLIGFIFAPLAFLTGIPWSDAVEAGSIMATKLLSNEFVAMTELGKASGLSERS
                     LGIVSVFLVSFANFSSIGIISGAIKSLNDEKGDMVARFGLKLLFGATLVSFVSAAIAGF
                     FL"
     gene            3998..4459
                     /locus_tag="NO87_RS08745"
                     /old_locus_tag="NO87_08745"
     CDS             3998..4459
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000551761.1"
                     /locus_tag="NO87_RS08745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08745"
                     /product="CtsR family transcriptional regulator"
                     /protein_id="WP_014614779.1"
                     /transl_table=11
                     /translation="MHNMSDIIEQYIKQLFEEAQDDVVEIQRANIAQRFDCVPSQLNYV
                     IKTRFTNEHGYEIESKRGGGGYIRITKVETKDQNNYIKRLMELIGPALSQQQALYIIDG
                     LRENQLITDREAKMIAAVVDRETLKMDVASRDIIRANILKRLLPVINYY"
     gene            4473..5003
                     /locus_tag="NO87_RS08750"
                     /old_locus_tag="NO87_08750"
     CDS             4473..5003
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019169091.1"
                     /locus_tag="NO87_RS08750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08750"
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="WP_063284842.1"
                     /transl_table=11
                     /translation="MKIDKRELDKHQNKHLEFHPIQAYDQSGYDQSDEQWHEGDDVEGT
                     FVIQQILQHLAAKHGLNVDQVVYREQKRCPNCQMTLKDIAHVGKFGCAQCYETFKEDVY
                     DIVRRVQGGHIEHSGKCPKSSQHKRALKKQLEEKRARLELLVAQQAFEEAAIVRDEIQA
                     LEQQSEVSQQDDA"
     gene            4993..5997
                     /locus_tag="NO87_RS08755"
                     /old_locus_tag="NO87_08755"
     CDS             4993..5997
                     /EC_number="2.7.14.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019169090.1"
                     /locus_tag="NO87_RS08755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08755"
                     /product="protein arginine kinase"
                     /protein_id="WP_015728601.1"
                     /transl_table=11
                     /translation="MMHNLDQHMSDWMKKVNAQPVIMSSRIRLARNLENYVHPLMFPSE
                     AEGHRVINEVQDVLTDLNVLRLDELDQLSKYKLVAKHLISPELTKQPASAVLLNEDESV
                     SVMVNEEDHIRIQAMGNDLSLNELYQKASAIDDILDRTLQISYDEQLGYLTTCPTNVGT
                     GMRASVMLHLPGLSIMKRMNRIAQTINRFGFTIRGIYGEGSQVYGHIYQVSNQLTLGKS
                     EQEIIDALTELVDQIIHEELALRERLNEHNHTETLDRIYRSLGILKYSRLISVEEASHR
                     LSDIKLGVDLGILDMEDFRFNELMVAIQSPFLIDETDEQSIEAKRAEILRTYI"
     gene            6013..8472
                     /locus_tag="NO87_RS08760"
                     /old_locus_tag="NO87_08760"
     CDS             6013..8472
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499078.1"
                     /locus_tag="NO87_RS08760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08760"
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="WP_014614776.1"
                     /transl_table=11
                     /translation="MLFGRLTERAQRVLAHAQEEAIRLNHSNIGTEHLLLGLMKEPEGI
                     AAKVLESFDITEDKVIEEVEKLIGHGQEQMGALHYTPRAKKVIELSMDEARKLQHNFVG
                     TEHILLGLIRENEGVAARVFANLDLNITKARAQVVKALGSPEMSNKNAQSAKSNNTPTL
                     DGLARDLTVIARDGTLDPVVGRNSEITRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLA
                     QAIVNNEVPETLKGKRVMSLDMGTVVAGTKYRGEFEERLKKVMEEIHHAGNVILFIDEM
                     HTLIGAGGAEGAIDASNILKPALARGELQCIGATTLDEYRKHIEKDAALERRFQPVQVN
                     EPSVADTIAILKGLRDRYEAHHRINISDEAVEAAAKLSDRYVQDRFLPDKAIDLIDEAS
                     SKVRLKSHTTPTNLKEIEQQIEQVKKEKDAAVHAQEFENAANLRDKQTKLEKQYEEAKN
                     EWQNHQGGQHTTLVAEDIAEVIAGWTGIPLTRLNETESERLLNLEDTLHERVIGQNDAV
                     IAISKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAEAMFGEEDAMIRVDMSE
                     FMEKHAVSRLVGAPPGYVGHDDGGQLTEKVRRKPYSVILFDEIEKAHPDVFNILLQVLD
                     DGHLTDTKGRRVDFRNTVIIMTSNVGAQELQDQRFAGFGGSSEGQDYETIRKTMMKELK
                     SAFRPEFLNRVDDTIVFHKLNKDELKEIVTMMVGKLTSRLSEQNINVRVTEAAKDKIAE
                     EGYDPEYGARPLIRAIQKTVEDNLSELILEGKELEGKNVTVDYDGETFQYDIHERETNE
                     DKEVTES"
     misc_feature    complement(8908..8926)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.93"
                     /tool="antismash"
     misc_feature    complement(8933..8946)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.42"
                     /tool="antismash"
     gene            9153..10004
                     /locus_tag="NO87_RS08765"
                     /old_locus_tag="NO87_08765"
     CDS             9153..10004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015728602.1"
                     /locus_tag="NO87_RS08765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08765"
                     /product="hypothetical protein"
                     /protein_id="WP_037543948.1"
                     /transl_table=11
                     /translation="MKTNIDYVFKDKSIYIKSDEQIFELSGISQESFIKIWNEIQEGHL
                     HCEEQDVVKKKIIEFLKTIHAFEDVANTASFLQMIGLKMEHKAFENHVIGICGDDDLVE
                     LYIRKSPSQNVVNLNEEVTDDYDIGLIILRKFNRKRITKCNEMMFNNGVPYNSVIFDNV
                     SFEVTYTIPKETSCLNCKRLRETENNVYGEVFSLFNDSSHESKEYVPEEIIQLALSFVA
                     VQMLKEAMQMNDLSVENELIQTVYAYSLLNEGWRTHNLFKHPNCELCFPESVNTQVFEV
                     RL"
     gene            10001..11221
                     /locus_tag="NO87_RS08770"
                     /old_locus_tag="NO87_08770"
     CDS             10001..11221
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614774.1"
                     /locus_tag="NO87_RS08770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08770"
                     /product="YcaO-like family protein"
                     /protein_id="WP_063284843.1"
                     /sec_met_domain="YcaO (E-value: 1.3e-41, bitscore: 137.5,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVKLKAQNFVDEKYGIIKNIYDLPTYYGLPKVYVKMAFGGQYNT
                     AGFNASGAGITEAQAVNSAVGEYIERYSCLHPHRVMKVSKGVVKINPQTINPSASANLD
                     DYQCIHGYDLIQKRTVALPVDAVYLTYRSNKKQSWMTTATGAACGPNLKACFWKGIAEI
                     FERDAFQYIWRRQIACEQIRINDNRELRSYFNRYIKSENIQFKLYKMDMDWDVPAVFGV
                     AILPNKGCVVAASVRPTWIEACKKTLLELAQSIVGYAAIIFKVDENIEVHSYDEVKEYQ
                     DHSLLYFNDHMSQHLSFLDGHQHIFRIPENEIQLDDDEAVTLFIEKIKSIDKQVYFVDV
                     TSEEIKHTDWKVGKTIIPGMLDIEPHFIKHLESSRLNEVDRNLIKMKKRQPNELKNSQP
                     IVPHPFP"
     gene            11241..12053
                     /locus_tag="NO87_RS08775"
                     /old_locus_tag="NO87_08775"
     CDS             11241..12053
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614773.1"
                     /locus_tag="NO87_RS08775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08775"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_063284844.1"
                     /sec_met_domain="PF00881 (E-value: 3.7e-19, bitscore: 63.4,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHFKSIMISNDYATRLSSKCVLSQTYHQNTKHSKRYLMSNMYQS
                     RVLLNSPNFLKATQSPERYFPTQQNFKLNAHSSGLLTEYLDKRRSQVHSPDKDAFIDLN
                     VLSDLFWAAYGKNSQNKRVVPSAGALYPLEIYGIVFNDYENFKKGLYHYNPSTHALSLL
                     DNGAHVFDISQYIMRYQNMEHPSIIFFITAVFSRATFKYDDRAYRYILLEAGAVAQNIS
                     LMATHYNLVSTSIGGTDDFKVEEMLKIDGNHESIVDCVFITKDREAVL"
     gene            12053..13012
                     /locus_tag="NO87_RS08780"
                     /old_locus_tag="NO87_08780"
     CDS             12053..13012
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614772.1"
                     /locus_tag="NO87_RS08780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08780"
                     /product="hypothetical protein"
                     /protein_id="WP_233508785.1"
                     /transl_table=11
                     /translation="MKEMIYFKRETPLQEISLFLRPYEKMNSDFAHVLEHILTARVKDD
                     GFHILGAHATEDYIKITLKDDFDIELFKPAPYLYEFNQQEFNRALSEIKQERALENKEI
                     KNIMNKMRGLKQDAIVNQDLEYYNGLLQNTLDTFSFIFINNDICNEVAHHVFFKDEVIE
                     KVTQPMTAKSGTLSHNKVEFFFKYINIPVHSIQEASTIFYIQKLIGFINKKMANLRSEG
                     IYYSIAFPMYSRKQIELFLLISFTEDVKRDFNLDIEKMLDAYDIHESIDINNGEQAYTY
                     KENLSVIYLSPKFLMNSIPPVNEEAIRITQQMIQKIIR"
     gene            13027..13731
                     /locus_tag="NO87_RS08785"
                     /old_locus_tag="NO87_08785"
     CDS             13027..13731
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614771.1"
                     /locus_tag="NO87_RS08785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08785"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_014614771.1"
                     /transl_table=11
                     /translation="MGNIFEINDVSKTFGKNKVLDAVDLSVNQGEIVGLLGLNGQGKST
                     LIKIVLGLLKQNSGKVIKNIDFKQQCGVVLQEVAMPEKMKVKEWLELLKSYSEHQQDTD
                     DILKEVDLVKEKNQYCTRLSGGQKRRLQYAAALVNCPQFLVLDEPTTGMDVASKELFWE
                     HVRSKVEEEKMSVLLISHDLEEIAAFATRIVILHKGKIVLNEQVEVLFNTFDHKGDKLK
                     KIFKEKVLYEKG"
     gene            13718..14464
                     /locus_tag="NO87_RS08790"
                     /old_locus_tag="NO87_08790"
     CDS             13718..14464
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013245.4"
                     /locus_tag="NO87_RS08790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08790"
                     /product="ABC transporter permease"
                     /protein_id="WP_015728605.1"
                     /transl_table=11
                     /translation="MKKAKSFLYLTQLNTRRIFRDFKYVLLIIALPMFFYVIYSEIFPQ
                     NAAVNGISWKEYSLISLICFGIMGNAINLLGTKVANEKNDNWYAYLKVSVINPNAYMMS
                     YLFSYFLISFIFSVAMILLGYFYNDIHIAFYKLVEIVILLNVFSFAFLFLALIIGQLGS
                     AAQPIGTIVYLLLSFLGGLWIPVDAMPKHMQAFAEILPSYRYGHIGWSILSEGRIHIED
                     VLYLIGYAILFFIIFLVLSKVNGKNK"
     misc_feature    complement(14558..14578)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 28.31"
                     /tool="antismash"
     gene            14851..16221
                     /gene="radA"
                     /locus_tag="NO87_RS08795"
                     /old_locus_tag="NO87_08795"
     CDS             14851..16221
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="radA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499080.2"
                     /locus_tag="NO87_RS08795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08795"
                     /product="DNA repair protein RadA"
                     /protein_id="WP_014614769.1"
                     /transl_table=11
                     /translation="MAKTKTIFECTACGYQSPKWMGKCPNCGAWNSMEESFEQKTASPK
                     HGVRAQKTSSAKIQKLDDIKQELAPRIQTNSGELNRVLGGGIVEGSLVLIGGDPGIGKS
                     TLLLQMCAALSKEKRVLYITGEESLNQTKIRADRLDEDASQLNVFAETDLMVIHEAVKK
                     VEPDLIVVDSIQTIYHPEISSAPGSVSQVRESTQSLMHIAKQMNVATFIVGHVTKEGQI
                     AGPRLLEHMVDTVLYFEGDEHHAYRILRAVKNRFGSTNEMGIFEMKQSGLKSVLNPSEM
                     FLEERTTNVAGSTIVATMEGTRPLLIEVQALVTPTTFNNPRRMATGIDHNRLSLLMAVL
                     EKKEGYLLQQQDAYIKVAGGVKLSEPAVDLGIVIATASSFKDQAVDGLDCYIGEVGLTG
                     EVRRVSRIEQRVQEAAKLGFKRVIIPKNNIGGWHFPEGIEVIGVTSVNEALKYALKN"
     gene            16240..17301
                     /locus_tag="NO87_RS08800"
                     /old_locus_tag="NO87_08800"
     CDS             16240..17301
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614768.1"
                     /locus_tag="NO87_RS08800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08800"
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="WP_063284846.1"
                     /transl_table=11
                     /translation="MDFIKLLVIVSYIIIGSVLGILLIPAVMIDFNVSHPPMMENSYVT
                     SIMGVAIMFLLFGWFIPRIAYAMKDLEQFVLGYSAIEIIFATIGLFMGLLISVMISFIL
                     EFIGTDLINRIVPILLTLSLSYLGFQFGLKKRDEMLLFLPENMARSMAINARNAVPKII
                     DTSAIIDGRILKIMEAGFIDGEILIPQGVINELQVVADANDSIKRDKGRRGLEILSAIH
                     LSKHPTRIIHPQRTHQDIDDLIVRLAQHYRAHVITTDYNLNKVCSIQGIKVLNVNDLSD
                     AIRPEVHQGDRFDLMITKVGKEPGQGVGYLDDGTMVVVDDAKQYVNETITLEVISILQT
                     ASGRIIFAKKVEA"
     gene            17302..18000
                     /gene="ispD"
                     /locus_tag="NO87_RS08805"
                     /old_locus_tag="NO87_08805"
     CDS             17302..18000
                     /EC_number="2.7.7.60"
                     /GO_function="GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166687.1"
                     /locus_tag="NO87_RS08805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08805"
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="WP_014614767.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.4e-13, bitscore:
                     44.7, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNYHVIIPAAGKGSRMGRPYNKLFIEVAGRRVLEHTLSVFQSDV
                     QCEGIHLAIHERDRDQLEVLTGPFSKVKSLVVGGETRQDSIHQVLQNVEFTNDDIVLVH
                     DGARPFVTHDTIHEVTAAIRTYGAAIVGVKAKDTIKRVSDQFVTETLDRATLWQVQTPQ
                     GATFELLASAYDHAKTQQMMGTDDASLIEAYGQRIYMVEGDYDNIKLTTEEDLTYAEAI
                     LEKRSRHHHV"
     gene            17993..18472
                     /gene="ispF"
                     /locus_tag="NO87_RS08810"
                     /old_locus_tag="NO87_08810"
     CDS             17993..18472
                     /EC_number="4.6.1.12"
                     /GO_function="GO:0008685 - 2-C-methyl-D-erythritol
                     2,4-cyclodiphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614766.1"
                     /locus_tag="NO87_RS08810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08810"
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="WP_014614766.1"
                     /transl_table=11
                     /translation="MFRVGLGYDVHAFDATRPLIIGGIEVPHTHGLKGHSDADVLLHAI
                     TDAMLGACALGDIGKLFPDTDPQFKDADSKKLLTEAYAEVQKEGYVINNIDATIIAEKP
                     KFRPYIDEMRAIIAGLFAVDIKRVNVKATTSEKLGFTGRQEGIAAQAIVSLTATT"
     misc_feature    complement(18505..18521)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: medium, score: 26.45"
                     /tool="antismash"
     gene            18549..20003
                     /gene="gltX"
                     /locus_tag="NO87_RS08815"
                     /old_locus_tag="NO87_08815"
     CDS             18549..20003
                     /EC_number="6.1.1.17"
                     /GO_component="GO:0009332 - glutamate-tRNA ligase complex
                     [Evidence IEA]"
                     /GO_function="GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gltX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002465549.1"
                     /locus_tag="NO87_RS08815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08815"
                     /product="glutamate--tRNA ligase"
                     /protein_id="WP_063284847.1"
                     /transl_table=11
                     /translation="MSNRVRVRYAPSPTGYLHIGNARTALFNYLFAKHYDGDFVIRIED
                     TDSKRNLADGESSQFDNLKWLGLDWDESVDKDKGYGPYRQSERGEIYQPLVEQLLAEDK
                     AYKCYMTEEELEAERQEQIARGEMPRYGGKHAHLTEEERQQFEAEGRKPAIRFRVPQNK
                     TYTFDDMVKGPVTFESDNFGDWVIVKKDGVPTYNFAVAVDDHYMEISDVIRGDDHISNT
                     PKQLMIYETFGWEPPRFAHMTLIVNEQRKKLSKRDGQILQFIEQYRDLGYLPEALFNFI
                     ALLGWSPEGEEEIFSKDEFIKIFTEKRLSKSPAFFDKQKLEWINNQYMKEKDAETVFEM
                     TLPHMIKAGLLPESPSEAELDWGRKLVALYQEQMSYAGEIVPLSELFFRDEKELDEASQ
                     EVLNGEQVPQLMIALYGKLEALENFEAAEIKKIIKEVQKETGIKGKQLFMPIRVAVTGQ
                     MHGPELPNTMEVLGQDKVLRRIQSLL"
     misc_feature    complement(18596..18610)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.62"
                     /tool="antismash"
     gene            20391..21056
                     /gene="cysE"
                     /locus_tag="NO87_RS08820"
                     /old_locus_tag="NO87_08820"
     CDS             20391..21056
                     /EC_number="2.3.1.30"
                     /GO_function="GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /gene="cysE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499083.1"
                     /locus_tag="NO87_RS08820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_08820"
                     /product="serine O-acetyltransferase"
                     /protein_id="WP_172425792.1"
                     /transl_table=11
                     /translation="MLFEGGVKVFRRMMDDVKMVFEQDPAARSTIEVITTYAGLHAVWS
                     HLIAHRLYQKKRYVLARAISQASRFFTGIEIHPGAKIGRRLFIDHGMGVVIGETCTIGD
                     NVTIYQGVTLGGTGKEKGKRHPDIGDNVLIAAGSKVLGNIKVHSNVNIGANSVVLQDVP
                     SYSTVVGIPGRIVKQDGRRIGKTFDHLNLPDPIYEQLKQLERQLEQTKNGEIKDDYII"
     misc_feature    21471..21491
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 23.54"
                     /tool="antismash"
     misc_feature    complement(21982..21998)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.12"
                     /tool="antismash"
ORIGIN
        1 agaagaagtt atgaatgctg tatctattcc ggtaatggcg aaatgtcgta tcggtcatat
       61 tacagaagca agagtattag aagcaatggg tgtagactac attgatgagt cagaagtgtt
      121 aacacctgca gatgaagtgt tccatttgaa aaaagatgaa tatacagtgc cattcgtttg
      181 tggctgccgt aacttaggtg aagcagcgcg tcgtatcggt gaaggtgctg cgatgttacg
      241 tacgaaaggt gaaccaggta cagggaatat cgtagaagcg gtacgtcata tgcgccaagt
      301 gaatcaagaa gtgaaacgta tcacagtaat gagtgatgac gaattgatga ctgaagcgaa
      361 aaacttaggc gcgccatatg aaatcttaaa agacattaaa aagcatggtc gtttaccagt
      421 cgtgaacttt gcggcaggtg gcgtggcaac acctcaagat gcggcattaa tgatggaatt
      481 aggtgctgac ggtgtattcg taggttcagg tatttttaaa tctgaagacc cagaaacatt
      541 tgctaaagcg attgtacaag cgacgacaca ttaccaagat tataaattaa ttggtgagtt
      601 agcgaaaaaa ctaggtacag caatgaaagg tatcgatatt aatcaacttt cattagaaga
      661 acgtatgcaa gagcgtggtt ggtaaaatga aaatcggtgt attagctttg caaggtgcgg
      721 tacgtgaaca tatccgtcat attgaacttg cgggtcatga aggtgtcgca attaaaaaag
      781 ttgaacaatt agaagaaatc gatggcttaa ttatccctgg tggcgaatcg acaactttac
      841 gccgtctcat gaatctttat ggttttaaag aggcgttacg tgcatcacaa ttacctatgt
      901 ttggtacgtg tgcaggctta attgtccttg cgaaagatat cgtaggcgaa gaaggctatc
      961 tgcaaaagtt agatattaca gtagagcgta attcatttgg gcgccaagtc gatagtttcg
     1021 agtctgaact acacattaaa ggtattgatc aaccgattga aggtgttttt attcgtgcac
     1081 cccatattca atcaacagaa gcagccgttg atgtattagg gacgattgat gacaaaatta
     1141 tcgctgtaca acaaggtcgt tatttaggcg tatcgttcca cccagaatta acagatgatt
     1201 atcgcatgac acaatatttt atagaacatg tgatgcagca gtaggaatag ataaaagtag
     1261 gctaggactt tcaaatggtc ctagccttta ctgttgtaaa acgatatggt gtgtataaag
     1321 aattgggtaa atcccccaat tacgttttca tacaaacatg gtgaggtgtc actttagatt
     1381 acggatttat tgaacaggat tttctaaaat atctttttta cctttgtacc atcgagcgat
     1441 atctttcgtt atgggttcca agattgcatt tttatcgtca tctcctcctt tgaccaatat
     1501 gccaaccaat tggtcattat cttctaaaaa tacagaggag ccagattggc caccgtatgc
     1561 aggtaagttt gttttaataa aatcactatt cgcgaaagtg atttctcctg tgaatctata
     1621 ttgtttatga gcgtggtagt tatatggata tccatatgaa tatacttttt ttccaaccat
     1681 tttttttaat tcgtcatctg tgaaaccttg aagttttatt tcagtttgtg cgaaatctct
     1741 ttgataatga atatagtcct tacttttccc gctatcttga ccatatataa aggcgatatc
     1801 tttgtcgtta taaggattaa ataaagatat ggacattgat ccaaaaggtg ttgatagtcc
     1861 tgattgagca gggtataccg taccgaccga tccttctaga aagccgtcgc cacaatgtgc
     1921 ggcagtgagt ccaaagttag aagtcaacat tgtagtagta cacggcagac cttttggacc
     1981 ttggaagatt gctgttctct ttgcgagcgg atcattttga atatcttcca cgaggatttt
     2041 cgttccttct tctgcgcccc aaacattcgc agcgttagtg cccgtcatgc cgatagttgt
     2101 taaaagtaaa aatgttgaac tgaattttaa aaatgatttt ttcattgttg tcttcctttt
     2161 ctatgattta tttgtattaa actagtccgt taattctgta tgtattgatg atgcctttta
     2221 aataaagttg aagtcctcat ttgttgcata tttgataaaa atattttcct aatgatttat
     2281 taaaaaataa aaatacacaa tcacatgttt aaattatata atgattatct gatttaatcc
     2341 acttaaattt aaaaaagtat ttatgttatt tgataataga gaaaaattgt actatatttt
     2401 agcgtactat ggacatttct ttaacaatca aaataatact gcctaaatgt ttcactaaaa
     2461 atccgagatg ttcataataa aaaatgaaaa tgcttcttta acaattgaat ctgtcgccca
     2521 actaaaatgg tttgaaaatg cacaacaaaa aagagactca gccatcatga ctcagtctct
     2581 taatatgtgt tatatttgtt tatcttttcc catactttag atgcagctta caagaaaaag
     2641 cctgcgattg ctgcggatac gaatgatacg agtgttgcac cgaataataa ttttaatccg
     2701 aaacgtgcta ccatgtcgcc tttttcgtca tttaatgatt tgatagcacc tgagatgata
     2761 ccgattgagc tgaagttagc aaacgatact aagaataccg acacgatacc taatgaacgt
     2821 tctgataaac cagatgcttt gccgagttca gtcatcgcta cgaactcatt agataatagt
     2881 tttgttgcca tgatcgagcc agcttctact gcatcactcc atggaatacc tgttaagaaa
     2941 gcaagtggtg caaagataaa gccgattaat gtttggaagt tccaatctaa tgcgccgcca
     3001 gaaatgaggc taatgagacc accaacaagt ccattcaata atgagatgag ggcgatataa
     3061 ccgattaaca tcgcgccgac gattacagcg actttaaatc catctaaaat gtattcccct
     3121 aacatttcaa agaaggattg ctttttcttt tcttcttcaa gcaataactt atcttcttct
     3181 tcatccactt tataagggtt aataatggaa gcaatgataa acccacctaa taagttaagg
     3241 acgaccgcag ttaccacata tttaggttgt actaatgtga agtacgcacc aataatcgat
     3301 gcagacacag tggacatcgc cgaagctgtt aatgtataca aacgttgctt cgtaatgtaa
     3361 ggtaattgtt ttttaagtga aataaatacc tctgattgtc caaggatggc tgcagcaaca
     3421 gcgttgtatg attctaaacg tcccatgcca ttaatttttg agattaagaa acctaaaata
     3481 ttaataatta aaggcaatat ttttgtatat tgtaaaatac caattaaggc agaaatgaaa
     3541 acgataggta ataaaacgct taagaaaaat gacatttgac cgttattgac aagaccaccg
     3601 aaaacaaaat caataccgac accggcttgt ttgagtaagt aaccgaatcc tgttgcgata
     3661 ccacctacaa tggtaatccc aatttttgtt ttcagtaaag catatgctaa gatgagctga
     3721 ataacaaaca taataccaat gtatttccaa cgtatgccct ttttatcaga acttccaata
     3781 aaagcgaggg ctaagaaaac accaatcccg atgaccccaa ttaaaatatg catgtgtgtt
     3841 ccacctctat tttttctaaa taatttttac taagactatc atacaacaaa aatgtaagca
     3901 gtaacataac tatttatcaa atttaaaatc aaattggttg aaaaaggtca aagtgggttc
     3961 tataatatag tcaaagatgg tcaaaagggg tgataccatg cataatatgt ctgacatcat
     4021 agaacagtac attaagcaat tatttgaaga ggcacaagat gatgtagttg aaattcaacg
     4081 tgccaatatt gcacaacgtt ttgattgtgt accatctcag ttgaattatg ttattaagac
     4141 gcgctttact aacgaacacg gttatgaaat tgaaagtaaa cgcggcggcg gtggttatat
     4201 tcggatcaca aaagttgaaa cgaaagatca aaacaattac attaaacgtt taatggagtt
     4261 gattggtccg gccctttctc aacaacaagc tttgtatatt attgatggct tgcgtgaaaa
     4321 tcaattaatt acggaccgag aagcaaaaat gattgcggcg gtggtggatc gggaaacatt
     4381 aaaaatggat gtcgcgtcga gagatattat ccgtgcaaat attttaaaac ggttacttcc
     4441 cgtaattaat tattattaga aggtgatgtg caatgaaaat cgataagcgt gaacttgata
     4501 aacatcaaaa caaacacctt gaatttcatc ctattcaagc gtacgatcaa tcaggttatg
     4561 atcaatctga cgaacaatgg catgaaggtg atgacgttga aggcacattc gtcattcaac
     4621 aaattttgca acatttggca gcaaaacatg gtctgaatgt ggatcaagtt gtttatcgag
     4681 agcaaaaacg ctgtccgaac tgtcaaatga cgttgaagga cattgcacat gtcggcaaat
     4741 tcggctgcgc gcaatgttac gaaacattta aagaagacgt gtatgacatt gtgagacgtg
     4801 tccaaggcgg tcatatcgaa cattcaggga aatgtccgaa gtcatcacag cataaacgtg
     4861 cgctgaaaaa gcaactagaa gaaaaacgtg cacgccttga attattagtc gcgcaacaag
     4921 cctttgaaga agcggcgatt gtgcgtgatg agattcaagc acttgagcaa caaagcgagg
     4981 tgtcccaaca agatgatgca taatttagac caacatatga gtgattggat gaaaaaggtg
     5041 aatgcgcaac cggtcattat gtcctcgcgt attcgtttag cacgtaacct tgaaaattat
     5101 gtgcacccac tcatgtttcc atctgaagct gagggacatc gcgtcattaa tgaggtgcaa
     5161 gatgtattaa cagacttaaa tgtactccgc ttagatgagc tcgaccagtt gagtaaatat
     5221 aagctagtag ccaaacactt aatcagtcct gagttgacga aacaaccggc atctgcagta
     5281 ctgttgaatg aagatgagtc ggtaagtgtg atggtgaatg aagaggatca tattcgtata
     5341 caagcaatgg gcaatgattt gtcattaaat gaactttatc aaaaagcatc tgctatagat
     5401 gatatattag atcgtacgtt acaaatcagt tatgacgagc aactcggtta tttaacaacg
     5461 tgtccaacga atgtcggtac agggatgcgt gcgagtgtca tgttgcattt gcctggttta
     5521 tccattatga aacggatgaa ccgcattgcg cagacgatta accgttttgg ctttacgatt
     5581 cgagggattt atggtgaagg ctcacaagtt tatggccata tttatcaagt ttcaaatcag
     5641 ctgacgttgg gaaaaagtga gcaagagatt attgatgctt taacagaatt agttgatcaa
     5701 attattcacg aagaactggc tttacgtgag cgattaaatg aacacaatca taccgagaca
     5761 ttagatagaa tatatcgttc tttgggtata ttgaagtata gtcgtttaat ttcggtggaa
     5821 gaagcgtccc accgtttaag tgatattaag ttgggcgtcg atttaggcat tttagatatg
     5881 gaagattttc gatttaatga attaatggtc gcgatacagt caccattttt gatagatgag
     5941 acagatgaac aatctattga agcaaaacga gcagagattt taagaacata tatataaata
     6001 ggaggttggc atatgttatt tggaagatta acagaacgtg cgcaacgtgt actcgcgcat
     6061 gcacaagaag aagcaattcg tttaaaccat tcgaatattg ggacggaaca tttattactc
     6121 gggttaatga aagaacctga aggcattgct gcaaaagtat tagaaagctt tgacattaca
     6181 gaagataaag tgattgaaga ggttgaaaaa ctcattggcc atggtcaaga gcaaatgggt
     6241 gctttacact atacaccacg tgccaaaaaa gtaatcgaac tttctatgga cgaagcacgt
     6301 aagttacaac acaacttcgt cggtactgaa cacatcttgt taggtttaat ccgcgaaaat
     6361 gaaggtgttg ccgcacgtgt atttgcaaac ctagacctca atattacaaa agcacgtgca
     6421 caagtggtga aagcgttagg tagcccagaa atgtctaata aaaatgcaca atctgcaaaa
     6481 tcaaataaca caccgacatt agatggccta gcgcgtgatt taacagtgat tgctagagat
     6541 ggtactttag atccagttgt aggtcgtaat tcagaaatta cacgtgtgat tgaagtgttg
     6601 agtcgtcgca caaaaaataa tcctgtgttg attggtgaac ctggtgttgg taaaacagcg
     6661 attgctgaag gtttggcgca agcaattgtc aacaacgaag taccagaaac gttgaaaggt
     6721 aaacgtgtca tgtcattaga tatggggact gttgtggctg gtacaaaata tcgtggtgaa
     6781 tttgaagaac gtttgaaaaa agttatggaa gaaattcatc atgcgggcaa tgtgattctg
     6841 ttcattgacg aaatgcatac gctcattggt gcaggtggtg cagaaggtgc gattgatgcg
     6901 tctaatattt taaaaccagc gcttgcacgt ggtgaattac aatgtatcgg tgcgacaact
     6961 ttagatgaat accgtaagca tattgaaaaa gatgctgcac ttgagcgtcg tttccaacct
     7021 gttcaagtca atgaaccaag cgtggcagat acaattgcaa tcttaaaagg tttacgagat
     7081 cgttacgaag cgcaccatag aattaatatt tcagatgaag cggtggaagc ggcagcaaaa
     7141 ttaagtgatc gatacgtaca agaccgtttc ttaccagata aagcgattga cttgattgat
     7201 gaagctagtt caaaagtgcg cttgaaaagc catacaacac caacgaactt aaaagaaatt
     7261 gaacaacaaa tcgagcaagt gaaaaaagaa aaagatgcag cagtgcacgc acaagaattc
     7321 gaaaatgctg caaacttacg tgacaaacaa acaaaacttg aaaaacaata tgaagaagca
     7381 aaaaacgaat ggcaaaatca tcaagggggc caacatacaa cactagttgc tgaagatatt
     7441 gctgaagtga tcgcaggttg gacaggtatc ccattaacac gcttgaatga aacggagtca
     7501 gaacgtttac tgaatttaga agatacattg catgagcgag taatcggaca aaatgatgcg
     7561 gtaatcgcta tttctaaagc agtacgccgt gcgcgtgcag gcttgaaaga tccgaaacgt
     7621 ccaatcggaa gcttcatctt cttagggcca acaggtgtcg gtaaaacaga acttgcacgt
     7681 gctttagctg aagcgatgtt tggtgaagaa gatgcgatga ttcgtgttga tatgagtgag
     7741 ttcatggaga aacatgcggt gagtcgtctt gttggggcgc ctcctggata tgttggtcac
     7801 gatgatggtg gtcaattgac tgaaaaagta cgtcgcaaac catattctgt tatcttgttt
     7861 gatgagattg aaaaagcaca cccagatgtc tttaacattc ttttacaagt attagatgat
     7921 ggacatttga ctgatacaaa aggccgtcgt gtggatttta gaaatacagt gattattatg
     7981 acatccaatg tcggggcgca agaacttcaa gaccaacgtt ttgcaggttt cggtggtagt
     8041 tcagaaggtc aagactatga aacaattcgc aaaacgatga tgaaggaact gaaaagtgca
     8101 ttccgtcctg agttcttgaa ccgtgtggat gacacgattg ttttccataa attaaataaa
     8161 gacgaattga aagaaatcgt tacaatgatg gtcggcaaat tgacgagtcg tctttctgaa
     8221 caaaacatta atgtacgtgt gacagaagcg gcgaaagaca agattgctga agaaggctac
     8281 gacccagagt atggtgcacg tccattgatt cgtgcgatcc aaaaaacggt tgaagataac
     8341 ttgagtgaat tgattttaga aggtaaagag ttagaaggta aaaatgtgac tgtagactat
     8401 gatggagaaa cattccaata tgatattcat gaacgtgaaa cgaatgaaga taaggaagtc
     8461 acagaatcat aagttactcg attaaagcag tgaaggcatt ctcttttttg agatgtctcc
     8521 gctgcttttt ttgtgtgaaa tttgcaatgt tgcaaagtcg actgtgttct taataagagt
     8581 cagttgatga tgtttggcgt gaggtgtgaa ttaatcgaaa ccttattgat ttttaacaga
     8641 taaaagtaat attaataaaa ggaataaaat caatatctaa tgctgtcttt acgttgaaca
     8701 gtcgagagat gtcttttttc taaacaaagt aaattactta ttacacaatt cttaattaat
     8761 gattaatatt ctaatataag ggttataata cattgccttt agaatggagt ggtagtatta
     8821 taaaaatgta aagataatga aacgaggcgt tataatatgt tttttaaaga gaataaaaaa
     8881 ctatttattg ttttaggcgc tttgattatt ggattgttat acagtttcct ttttgttttt
     8941 taaaatttga aaaggggtgg ttacaatgtt agccaacgaa ttacaaatca aaaaattgaa
     9001 cactgaagac tttttatcaa gcgaacaaat gaactggaca ataacacttt gttgttgccc
     9061 ttgctgctgt tgttgttaaa gtatatgttt taaaggaatt gaagttaacc atagcttcaa
     9121 ttcctttttt gaaaatgaga ggagagcaca tcatgaaaac aaacatcgat tacgttttta
     9181 aagataaaag tatatacata aaaagtgacg agcagatttt tgaattaagt ggtatctctc
     9241 aagagtcttt tattaaaata tggaatgaaa tccaagaagg tcatttgcat tgtgaggaac
     9301 aagatgtggt gaagaaaaaa ataattgaat tcctcaaaac aattcatgca tttgaagatg
     9361 tcgccaatac agcatccttt ttgcagatga ttggattgaa aatggagcat aaagcgtttg
     9421 aaaatcatgt cataggtata tgtggagacg atgatttagt cgaactgtat attcgaaaat
     9481 caccttctca aaatgtagtg aatttaaatg aagaagtaac ggatgattat gatatcggat
     9541 taatcatact gagaaaattt aatagaaaaa gaattacaaa atgtaatgaa atgatgttta
     9601 acaatggcgt accatataat agtgtcattt ttgataatgt ttctttcgag gtcacttata
     9661 cgatacccaa agaaacgagt tgtttgaatt gtaagcggtt acgagaaact gaaaataatg
     9721 tatatggcga agttttttcg ctattcaatg attcatctca cgaaagtaaa gaatacgtac
     9781 cagaagaaat cattcaactg gcattgagtt ttgtggcagt acaaatgtta aaagaagcaa
     9841 tgcaaatgaa tgacttgagt gttgaaaatg aactgatcca aacagtgtac gcttattctt
     9901 tattaaatga aggatggcgc acgcacaatt tattcaaaca ccccaactgt gaattgtgct
     9961 tcccagaatc agtgaataca caagtttttg aggtgagatt atgacagtga aattaaaggc
    10021 ccaaaacttt gtggacgaaa aatacggtat tattaaaaat atatatgatt tgccgacata
    10081 ttatggacta cctaaagttt atgtgaaaat ggcctttggg ggtcagtata atactgcagg
    10141 atttaatgcg agtggtgccg gtattacaga agcacaggct gtaaattcgg ctgtaggaga
    10201 gtacatcgaa cgctattctt gtttgcaccc tcatcgtgtc atgaaagtaa gtaaaggggt
    10261 agtaaaaatc aatccacaaa caattaaccc gtctgcaagt gcgaaccttg atgattacca
    10321 gtgtattcat ggttatgact tgattcaaaa aagaaccgtc gcactccctg tagatgcagt
    10381 gtatctcact tatagaagta ataagaagca aagttggatg acgacagcaa ctggcgctgc
    10441 gtgtggaccg aatctcaaag catgtttttg gaaaggtatt gcagaaatat ttgaaagaga
    10501 tgctttccag tatatttgga gaagacaaat tgcttgtgaa caaattcgta tcaatgataa
    10561 cagagaatta agaagttatt ttaatcgtta tatcaaatct gaaaatattc aatttaagtt
    10621 atataaaatg gatatggatt gggatgtacc cgctgttttt ggagtggcta ttcttcccaa
    10681 caaaggatgt gttgtcgccg cgagtgtgag acctacatgg attgaggcgt gtaaaaaaac
    10741 tttactggaa ttagcacaaa gtattgttgg gtatgcggca attattttta aagttgacga
    10801 aaatattgag gttcatagtt atgatgaagt gaaagaatat caggaccatt ctcttttata
    10861 tttcaatgat catatgtcgc aacatttgtc gtttcttgat ggccatcagc acatttttcg
    10921 gattcctgaa aacgagatac aactagatga cgatgaggca gtgactttat ttatagaaaa
    10981 aataaagtct attgataagc aggtgtattt tgtagatgtg acttctgaag agataaaaca
    11041 tacggattgg aaagtaggga aaacgattat ccctggaatg cttgatatag agccacattt
    11101 tattaaacat ctagaaagta gccgccttaa tgaagtcgat aggaatctaa ttaaaatgaa
    11161 gaaaaggcag cctaatgagt taaaaaatag tcaaccgatt gtcccacatc ctttcccata
    11221 atattttaaa ggagtatgcc atggaacatt tcaaatctat aatgatcagt aatgattatg
    11281 cgactcgatt aagttcaaaa tgtgtattga gtcaaacata tcatcaaaat acgaagcata
    11341 gcaaaagata tttaatgagc aatatgtatc aatctagagt tttattaaat agtccgaatt
    11401 ttcttaaagc gacacaaagt ccggaacgct attttccaac acaacaaaat ttcaaattga
    11461 atgcacattc atctggtttg ctaacagaat acctagataa gagaagatct caagttcata
    11521 gtccggataa agatgctttt atcgatttaa atgtcctttc agatttgttt tgggcagctt
    11581 atggaaagaa tagtcaaaat aaacgggttg tcccttcagc gggcgcttta tatccgttag
    11641 aaatatatgg cattgttttt aatgattacg aaaattttaa aaaaggactc taccattaca
    11701 atccttcgac gcatgctctc agtctgttag ataatggcgc gcatgttttt gatatctccc
    11761 aatatattat gagatatcaa aacatggaac atccttctat tatatttttt attacagctg
    11821 ttttttcaag ggctactttt aagtatgacg acagggcata cagatatatt ttgctagaag
    11881 caggcgctgt ggctcaaaat atttcactta tggcaaccca ttacaattta gtgagtacct
    11941 ctataggggg gactgacgac tttaaagtag aagaaatgtt aaaaattgat ggtaatcatg
    12001 aaagtatcgt tgactgtgta tttataacta aagatagaga ggcggtttta tgatgaagga
    12061 aatgatatat tttaaaagag aaacgccatt acaagaaatt tcattattcc ttagacccta
    12121 tgaaaaaatg aacagtgact ttgcacatgt actcgagcac attttaacgg caagagtaaa
    12181 ggatgacggt tttcatattt taggtgcaca tgcgacagaa gattacatca aaatcacttt
    12241 gaaagatgac tttgatattg agctttttaa acccgctcca tatttatatg aatttaatca
    12301 gcaagaattc aacagagctt tgagtgaaat taaacaagag cgtgcacttg aaaacaagga
    12361 aatcaaaaat attatgaaca agatgagagg tctgaaacaa gatgcaatag tgaatcaaga
    12421 tttggaatat tataacggac tacttcaaaa cacgctggat actttctcgt tcatcttcat
    12481 caataatgac atatgtaatg aagtggctca tcatgttttt tttaaagatg aagtgataga
    12541 aaaggtgaca caaccgatga cagcgaaaag tggaacgcta tcacacaaca aagtcgagtt
    12601 tttcttcaag tatattaata tcccagttca ttctatccaa gaagcatcaa ctatttttta
    12661 cattcaaaaa ttaatcggat tcatcaataa gaaaatggcg aacttaagaa gcgaagggat
    12721 atattatagt attgcatttc ctatgtatag tagaaagcag attgaattgt ttctacttat
    12781 ttcctttaca gaagacgtga aacgggattt taatttagac attgaaaaaa tgttagatgc
    12841 atacgatatt catgaatcaa tagatatcaa taacggagaa caggcttata cgtataaaga
    12901 aaatctttca gtgatatatc tttcccctaa atttttaatg aattctatcc ctccagttaa
    12961 tgaagaagct attcggatta cgcaacaaat gattcaaaag ataatccgtt aaggagtttg
    13021 aataatatgg gcaatatatt tgaaattaat gatgtgagta aaacttttgg taaaaacaaa
    13081 gtgctggatg ctgttgactt gtcggtcaat caaggtgaaa ttgtaggtct tttagggttg
    13141 aatggccagg gaaaatccac actgattaaa atagtgctag gtctactcaa acaaaattca
    13201 ggtaaggtga taaaaaatat cgatttcaaa caacaatgtg gtgttgtgtt acaagaagtg
    13261 gcaatgcctg aaaaaatgaa agtgaaagaa tggttagagc ttttaaaaag ttactcagag
    13321 catcaacaag atacagatga catattaaaa gaagtcgatt tagtgaagga aaaaaatcaa
    13381 tattgcacgc gcttatcagg gggacaaaaa agaagactac aatatgcagc agctctagtg
    13441 aattgccctc agtttttagt gcttgatgaa ccaacgacag gcatggacgt tgcttctaaa
    13501 gagttatttt gggaacacgt tcgctcgaaa gtcgaagaag aaaagatgag tgtgttgttg
    13561 attagtcacg atttagaaga aatagccgcc ttcgctacaa gaatcgtgat tctccataaa
    13621 ggtaaaatag tgttgaatga gcaggtagaa gttttattca atacctttga ccataaaggt
    13681 gacaagttga agaaaatttt taaggagaaa gttttatatg aaaaaggcta aatcatttct
    13741 atacttaact caactcaata cgcgaagaat atttagggat tttaagtatg ttttattaat
    13801 tatcgcattg ccaatgtttt tctatgttat atattctgag atttttccac aaaatgcagc
    13861 agtcaatggt atcagttgga aggaatactc actcatttct ctgatctgct ttggtataat
    13921 gggaaacgcg attaatttac ttggaacaaa ggtagcaaat gaaaaaaatg ataactggta
    13981 tgcatatctt aaagtgtctg tcattaatcc gaatgcctat atgatgagtt acttattctc
    14041 atactttctt atatctttca tcttttccgt cgcaatgatt ttgttaggtt atttttataa
    14101 tgacattcat atcgccttct ataaactggt agaaatcgtg atattgttga atgttttcag
    14161 ttttgcattt ttatttttag ctttaatcat tggccaactc ggttcagccg cgcagccgat
    14221 aggtaccatt gtttatttgc ttttgtcttt tttagggggg ctatggattc ctgtcgatgc
    14281 gatgccgaaa catatgcaag cttttgctga gatattacct tcatatcgtt acgggcatat
    14341 tggatggagc attttaagtg aagggcgtat ccatattgag gacgttttat atttaatagg
    14401 ttatgcgata cttttcttca tcatcttttt agtgctatcg aaggtgaatg gcaaaaataa
    14461 ataaactatt ttattcaatg gcacaagtca tgcgattgac tgcaatggac ctacgctgta
    14521 tttaaaatag aaacaaaaaa gggacggtta caaatggggt atagcctttg ctatgtcagt
    14581 tgtaatcgtc ttttgtcttt ggctttagtg cgtcaagtgg gttgtagttt attttactga
    14641 tgatagagct ggttatttga gctttctatt tcctgttttg tgttgtacag gctacatttt
    14701 taagtatttg ctgtatatta tttataattg gatagtgtgt ttcgatgaga acggatattt
    14761 aaagcgttta aatgataaag ggcaacattt gtcagaaaca tttttcaagt ataaaataga
    14821 tatgttatat gacgagatgg gggtgtctga gtggcaaaaa caaaaacaat ttttgaatgt
    14881 acggcctgtg gttatcaatc gcctaaatgg atggggaaat gtccaaattg tggtgcttgg
    14941 aattcaatgg aggaatcttt tgaacaaaaa actgcgagtc ctaaacacgg tgtacgggcg
    15001 caaaaaacaa gttcagcaaa aatacaaaag ctcgatgaca ttaaacaaga gcttgcgcca
    15061 cgtatccaaa cgaatagtgg tgaattaaac cgtgtgctcg gtggcggtat tgtagaaggg
    15121 tcactcgtgc tgattggtgg cgatccagga atagggaagt ccacattgtt acttcaaatg
    15181 tgcgcggctt tatctaaaga gaaaagggtg ctctatatta ctggtgagga atcactcaat
    15241 caaactaaaa ttagagcgga tcgtttggat gaagatgcga gtcaacttaa cgtgtttgcg
    15301 gaaacggact taatggttat tcatgaagcg gtgaaaaagg tcgaacctga tttaattgta
    15361 gtggactcta ttcagacgat ctaccatccc gaaatcagtt cggcgcctgg ctctgtatct
    15421 caagttcgtg aaagtacaca aagcttgatg cacatcgcaa aacaaatgaa tgttgcgacg
    15481 tttattgtag gccatgtgac taaagaaggc caaatcgcgg ggccgcgttt acttgaacat
    15541 atggtggata cggtgcttta ttttgaaggt gatgaacatc atgcgtatcg tattttaaga
    15601 gcggtgaaaa accgttttgg ctctacgaat gaaatgggta tttttgaaat gaaacagtca
    15661 ggtttaaaaa gcgtgcttaa cccgtcagaa atgtttttag aagaacggac gaccaatgtt
    15721 gcaggttcga caattgtcgc aacgatggaa gggacacgac cattgttaat tgaagtacaa
    15781 gcgcttgtca caccgacgac gttcaataat ccgagacgta tggcgacagg tattgaccat
    15841 aatcgcctca gtttgttaat ggcggtgtta gagaaaaaag aaggttattt attacaacaa
    15901 caagacgctt acattaaggt agcagggggc gtcaaactct ctgaacctgc tgtcgactta
    15961 ggtatcgtca ttgcgacagc ttctagtttt aaagaccaag cagtagacgg cctcgattgt
    16021 tatattggcg aggttggatt gactggtgag gtccgccgtg tttcgcgcat tgagcaacgt
    16081 gtgcaagaag cagcaaaatt gggctttaaa cgtgtgatta tccctaaaaa caatattggc
    16141 ggatggcact tcccagaagg tattgaagtg attggcgtga cttctgtcaa tgaagcattg
    16201 aaatacgcat taaaaaatta gaaaggaggg atgatagagg tggattttat taaattatta
    16261 gtgattgtgt cttatattat tattggtagt gtgttaggca tactcttaat ccctgctgtc
    16321 atgattgatt ttaatgtcag tcatcctcca atgatggaga atagttatgt gacgtcgatc
    16381 atgggtgttg ctatcatgtt tttattgttt ggttggttta tcccccgtat tgcgtatgcg
    16441 atgaaagatt tagagcaatt tgtgttgggg tatagtgcta ttgaaattat cttcgcaacg
    16501 attggtttgt ttatggggct actcatatct gtcatgattt cctttattct tgagtttatt
    16561 ggaacggatt tgattaaccg tatcgtccct atcctactta cattaagttt aagttatctc
    16621 ggttttcaat ttggtctaaa aaaacgtgat gaaatgctgt tgtttttacc agaaaatatg
    16681 gcgcgttcga tggcgattaa tgcccgcaat gctgtgccga aaattattga tacgagtgcg
    16741 attattgatg gtcgtatttt aaaaattatg gaagcgggat ttattgatgg cgaaattctc
    16801 attcctcaag gtgtcattaa tgagttgcaa gtcgtcgcgg atgcgaatga tagtattaag
    16861 cgtgataaag ggcgccgtgg tttagaaatt ttaagtgcga ttcatctgtc gaaacacccg
    16921 acacgtatta ttcacccgca acgtacacac caagacattg acgacttaat tgtaaggtta
    16981 gcgcaacatt atcgcgcgca cgtgattaca acggattata acttgaacaa agtatgcagc
    17041 atccaaggaa tcaaagtgtt aaatgtcaat gacctatctg atgcgattcg acctgaggtg
    17101 catcaaggcg atcgttttga cttgatgatt acaaaagttg ggaaagagcc tggccaaggt
    17161 gtcggttatt tagatgacgg cacaatggtg gtcgtggatg atgcaaagca atacgtgaat
    17221 gaaaccatta cacttgaagt aatcagtata ttacaaactg catcagggcg aattattttt
    17281 gcgaagaagg tggaagcata aatgtcaaat tatcacgtca ttataccagc agcaggcaaa
    17341 ggcagtcgta tgggacgtcc gtataataaa ctgttcattg aagttgcggg gcgccgtgtg
    17401 ttagagcata cgctttccgt ttttcaatcc gatgtacagt gtgaaggcat tcatttggcg
    17461 atacacgaga gagatcggga tcaacttgag gtattaacag gaccattttc aaaagtaaaa
    17521 agtttagtcg ttggcggtga gacacgtcaa gatagtattc atcaagtgct gcaaaacgtt
    17581 gagttcacga atgatgacat tgtccttgtg catgatgggg cacgcccgtt tgtcacgcat
    17641 gacacgattc atgaggtaac ggctgccatt cgaacatatg gggcggcgat tgtcggtgtg
    17701 aaggcaaaag atacgattaa acgcgtgtcc gaccaatttg tgacggaaac attggatcgt
    17761 gcgactttat ggcaagtgca gacgcctcaa ggtgcgacat ttgaactgct tgcttcagcc
    17821 tatgaccatg caaaaacgca acaaatgatg gggacggacg acgcctcgtt aattgaagct
    17881 tacggtcaac gcatttatat ggttgaaggg gattatgata atattaaatt aacgactgaa
    17941 gaagatttaa catatgcaga agcaatttta gaaaaaagga gtcgacatca tcatgtttag
    18001 agttggatta ggatacgatg tgcacgcatt tgatgcgaca cgccctttaa ttattggcgg
    18061 gattgaagtg ccacatacgc atggtttgaa agggcatagt gatgcagatg tcttgttaca
    18121 tgcgattaca gatgcgatgt taggggcatg tgcattaggt gatataggta agctatttcc
    18181 agatacggat ccacaattta aagatgcaga ttcgaaaaaa ttattaacag aagcgtacgc
    18241 agaagttcaa aaagaaggtt atgtcattaa taatattgat gcaacgatta ttgcggaaaa
    18301 accgaaattc cgaccttata tcgatgagat gcgcgcaatc attgcaggtc tttttgctgt
    18361 cgatattaag cgtgtgaatg tgaaagcgac gacgagcgaa aagttaggtt ttacagggcg
    18421 tcaagaaggg attgccgctc aagcgattgt gtcattaacg gcaacaactt aacctaagct
    18481 gtgatatgca taaatgggga tgacatgcta taatataaca attgaacaat gaaacaggag
    18541 tgaacgaaat gagtaaccga gtgagagtaa gatatgcacc aagtccaaca ggctatttgc
    18601 atattgggaa cgcacgtacg gcattattta actatttatt cgcgaaacat tacgatggtg
    18661 attttgtcat tcgtattgaa gatacagatt ctaaacgtaa cttagcggac ggtgaatcat
    18721 cacagttcga taatttgaag tggctaggtt tggattggga cgaatctgta gacaaagata
    18781 aaggctatgg accttatcgc caatcagaac gtggtgaaat ttaccaacct ttagtcgagc
    18841 agttattagc agaagataaa gcgtataaat gttatatgac tgaagaagaa ttagaggcag
    18901 aacgtcaaga acaaatcgca cgtggtgaaa tgccgcgtta cggtgggaaa catgcacact
    18961 tgactgaaga agaacgtcag cagtttgaag cagaaggacg caagccagca atccgtttcc
    19021 gtgtgccgca aaataaaaca tatacgtttg atgatatggt gaaagggcct gtcacatttg
    19081 aatctgacaa cttcggcgac tgggtcatcg tgaaaaaaga cggtgtacca acatataact
    19141 ttgcagtagc cgtggacgat cactacatgg aaatttctga cgtcattcgt ggtgacgacc
    19201 acatttctaa cacacctaaa caattaatga tttacgaaac atttggttgg gaaccaccac
    19261 gctttgcgca tatgacttta atcgttaatg aacaacgtaa aaaattaagt aaacgtgacg
    19321 gtcaaatttt acaatttatc gagcaatatc gcgatttagg ctatttacca gaagcgttat
    19381 ttaactttat cgcattgtta gggtggtctc cagaaggtga agaagagatt ttctctaaag
    19441 acgaattcat caaaatcttc actgaaaagc gtttatcaaa atcaccagca tttttcgata
    19501 aacaaaaatt agagtggatt aacaaccaat atatgaaaga aaaagatgcg gaaacagtat
    19561 ttgaaatgac attgccgcat atgatcaaag caggcttatt accagagtca ccatcagaag
    19621 cggagttaga ttggggtcgc aagttagttg cgctttatca agaacaaatg agctatgcgg
    19681 gtgaaattgt accgttatct gagttgttct tccgcgatga aaaagagttg gacgaagcat
    19741 cgcaagaagt attgaacggt gaacaagtgc cacaattgat gatagcatta tacggtaagt
    19801 tagaagcttt agaaaacttt gaagcggctg agattaaaaa aatcatcaaa gaagtccaaa
    19861 aagaaacagg cattaaagga aagcaattat ttatgccaat ccgtgttgca gtaacaggcc
    19921 aaatgcatgg acctgaatta ccgaacacaa tggaagtatt aggacaagat aaagtgcttc
    19981 gtcgtattca aagtttatta taaaaaaggg tatgttcgat tttcgtactt gatatcactt
    20041 tgaaaatcga ctactattaa agtggatttg aatagaataa aggacaagta agcaaacagc
    20101 gtgtgaatca gagagtgtac ggttggtgag agtgcaccac aaagtttgtt gaatgcacct
    20161 ttaggatgag agttgaataa ccaattgagt gagtatatgg atgcaaagtt taagctttga
    20221 acatgtacta attaagagtg gaaccgtgca catatcgcac ctctgacata tgacatgtta
    20281 gaggtgtttt tttcaattct gatcacactt tttaaggagg acaatgaagc caaggagtgg
    20341 gttgtccgtg aaagtcgttt ttcagttagt ttacaagaat aagtattgtc atgctgtttg
    20401 aaggaggggt taaagtgttc cgacgtatga tggatgatgt caaaatggta tttgaacaag
    20461 atccagcagc acgctcaacg atagaagtga ttacaactta tgcgggttta catgcggttt
    20521 ggagtcattt gattgcacac cgcttatatc aaaagaaacg ttatgtactt gcaagagcga
    20581 tttctcaagc ttcacgattt tttacaggta ttgaaattca tccaggtgct aaaattgggc
    20641 gccgtttatt tattgaccat ggtatggggg tggtcatcgg cgaaacatgt actattggtg
    20701 acaatgtgac gatatatcaa ggtgtgacat taggtggaac tggtaaagaa aaagggaagc
    20761 gtcatcccga cattggtgat aatgtcctta tcgcagcagg ttctaaagtg ttaggtaata
    20821 ttaaggtgca ttcaaatgtt aatatcggtg ctaattcggt cgtgcttcaa gatgttccaa
    20881 gttattctac ggtggtaggt attccaggac gtattgtgaa gcaagatggt agacgtatcg
    20941 gtaagacatt cgatcatctt aacttgccag atccaattta tgagcaactc aaacaactag
    21001 aacgacaact tgaacaaact aaaaatggag agattaaaga tgattacatt atataataca
    21061 ttaacacgtc aaaaagaagt gtttcagcct atcgaaccag gaaaagtgaa aatgtatgtg
    21121 tgtggcccaa ctgtgtacaa ttacatccat attgggaacg cacgtccagc gattaactat
    21181 gacgtggtcc gtcgttattt tgaatataaa ggttatgaag tgaattacgt ctcaaacttt
    21241 actgacgttg atgataaatt gattaaacgt tcacaagagt tgggcgaaac agttccagag
    21301 attgcggaac gttacattca agccttttat gaagatacag aggccctgaa tgttaaaaaa
    21361 gcgacgtcga atccgcgcgt gatggatcat atggatgaca ttattaaatt tattaaaaag
    21421 ttagttgatg aaggttatgc atatgaaagt ggtggcgacg tttatttcag aacgcgtcaa
    21481 tttgaagatt atggtaagtt gagccatcag tcgattgatg atttgaaagt cggtgcacgt
    21541 atcgagcaag gcgaaaacaa agaagatgca ctcgacttca cactatggaa aaaagcgaaa
    21601 ccaggtgaaa ttagttggga gagtccattc ggtgaaggcc gtccggggtg gcatattgaa
    21661 tgttcagtaa tggcctttga aaagctcggc cctacgattg atattcatgc tgggggaagc
    21721 gatttgcaat tcccacatca cgaaaacgag attgcacagt cagaagcgca taaccatgag
    21781 acgtttgcga actactggat gcacaacggt tttattaata ttgataatga aaaaatgagt
    21841 aagtctttag gaaacttcat tttagtccat gacattatta aagaagtgga cccagatgta
    21901 ttacgctttt tcatgattag tgttcattat cgaagtccaa tcaactacaa tttagaactt
    21961 gttgaagcag cgagaagtgg tttggaacgt attcgcaata gttatcaagc attgacggaa
    22021 cgtgaaactg tggcgacgga cttaacaaat gac
//
