LOCUS       NZ_JTKO01000003        22117 bp    DNA     linear   CON 11-APR-2024
DEFINITION  Staphylococcus pseudintermedius strain 2001-08-299-1 contig_3, whole
            genome shotgun sequence.
ACCESSION   NZ_JTKO01000003
VERSION     NZ_JTKO01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Staphylococcus pseudintermedius
  ORGANISM  Staphylococcus pseudintermedius
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus; Staphylococcus intermedius group.
REFERENCE   1  (bases 1 to 244448)
  AUTHORS   de Vries,L.E., Hasman,H., Jurado Rabadan,S. and Agerso,Y.
  TITLE     Sequence-Based Characterization of Tn5801-Like Genomic Islands in
            Tetracycline-Resistant Staphylococcus pseudintermedius and Other
            Gram-positive Bacteria from Humans and Animals
  JOURNAL   Front Microbiol 7, 576 (2016)
   PUBMED   27199912
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 244448)
  AUTHORS   de Vries,L.E. and Agersoe,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-DEC-2014) Department of Technology, University College
            Metropolitan, Sigurdsgade 26, Copenhagen 2200, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: SEP-2014
            Assembly Method                   :: CLC NGS Cell v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 20.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001622945.1-RS_2024_04_11
            Annotation Date                   :: 04/11/2024 12:27:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,368
            CDSs (total)                      :: 2,296
            Genes (coding)                    :: 2,259
            CDSs (with protein)               :: 2,259
            Genes (RNA)                       :: 72
            rRNAs                             :: 5, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1 (5S, 16S)
            partial rRNAs                     :: 1, 4 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 37
            CDSs (without protein)            :: 37
            Pseudo Genes (ambiguous residues) :: 0 of 37
            Pseudo Genes (frameshifted)       :: 13 of 37
            Pseudo Genes (incomplete)         :: 26 of 37
            Pseudo Genes (internal stop)      :: 7 of 37
            Pseudo Genes (multiple problems)  :: 9 of 37
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:20:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 204657
            Orig. end                         :: 226774
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JTKO01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22117
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="opine-like-metallophore"
                     /region_number="1"
                     /rules="(CntL and CntM)"
                     /tool="antismash"
     cand_cluster    1..22117
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(CntL and CntM)"
                     /kind="single"
                     /product="opine-like-metallophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22117
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:12117](+)"
                     /cutoff="5000"
                     /detection_rule="(CntL and CntM)"
                     /neighbourhood="10000"
                     /product="opine-like-metallophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12117
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(CntL and CntM)"
                     /neighbourhood="10000"
                     /product="opine-like-metallophore"
                     /protocluster_number="1"
     gene            712..2664
                     /gene="spsN"
                     /locus_tag="NO87_RS04405"
                     /old_locus_tag="NO87_04405"
     CDS             712..2664
                     /codon_start=1
                     /gene="spsN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614888.1"
                     /locus_tag="NO87_RS04405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_04405"
                     /product="LPXTG-anchored surface protein SpsN"
                     /protein_id="WP_015728543.1"
                     /transl_table=11
                     /translation="MLRTNYKLRKLKVGLVSTGVALTFVMASGNAEASENEQTEVKGEA
                     QVASVNEKESEAELPVAQQEASIQLDKVQPGDAQLSGYTQPNKAISVKIDNKDIVSVDD
                     GYEEVLSDDTGKFVYDLKGRQIVYNQKVDVEAMTPFNFEDFDESALESEEALEALGQLE
                     DEETATASVTTPRYEGAYTVPEERLTPIQGQQQVFIEPILEGASKIKGHTSVQGKVALA
                     INQEHVHLGDTLEEQAALTGQEWQGRYDGIWRHIDDQGFFEFDLNRLYNKSYPLKSGDL
                     VTLSFKSNDEVGPLFNVNVEPFERVAQAKTKYEQNDSPVVNKLDDTKSDLEVQPIYGDL
                     TQAAVHGESKVLIPGTSKVEGRTNYAHAWIEMASNLGEYRSFPTLQADATGAFIFDLKA
                     ADIQLLNGERLTFRAVDPHTKQQLAETTSEVRPVDMQDEESEVVQTSSTEKSALADEIL
                     RSMTIDKSFNPEVTEIPGHVYPKKTEDKGPENTEQASENSEKPSQTTESQNDAVQDVEK
                     SSVNEEVTPPSTESAQVEKGQNTEGALLPKNVEQHVESIPYQKRKALIGLTKHQGSGHM
                     PPFSLSFNNKEDDVSTKVNEANEHERKQGTVYPEQIEQLPQTGLTEKSPFWALLFVVSG
                     TGLLLFKRSRRQRQS"
     gene            3324..5378
                     /locus_tag="NO87_RS04410"
                     /old_locus_tag="NO87_04410"
     CDS             3324..5378
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614887.1"
                     /locus_tag="NO87_RS04410"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_04410"
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="WP_015728544.1"
                     /transl_table=11
                     /translation="MNQYNQKSIYRIRKYTVGVVSVLATMTFLIGGHDAMASEQHTTQA
                     SSELARTEVTVSNQSLSEDTHTQSLSQKEGQHSHSGDSKNPKTSLFANASSQEQLPTTP
                     EQGVSSDNPNTSHPTHINENTNVPSLVDIQQEKGEKLSDVPNSEKVKTQSGSQIEAPPH
                     SNSRKAGRIAENQDLTSQQSDVALKDQSDVEVSKRVNHRSSEAMRARNVEKAQTDEIDQ
                     MTSQNLKPVVKDKTDQGKEQAIAEHKDQTKKGASEEEMTQKETTQEQQSQTRVANSKEV
                     LEKSSTQAQQKQSTNKYPIVLVHGFLGLVGENAPALYPNYWGGNKFKVIEALRKKGYDI
                     HQASVGAFSSNYARAVDLYYFIKGGRVDYGAAHAAQYGHERFGKIYKGIMPDWRPGKKV
                     HLIGHSMGGQTVRLMEELLRNGSKDEIAYHQKHGGTISPLFKGGLTDMVSSITTLGTPH
                     NGSQAADQVANKEFVRHIMYALSRVAGSEYSDFDLGLRHWGFKQRPGESYFDYMKRVSE
                     SPIWQTKDNAAYDLTLEGSAILNQKTSLNPNITYTTYTAEASHKGASGKEVPNVGVFPL
                     MDLTSRIIGSDARLEWRKNDGVVAVISSLFPLNQPFVKVSSDALATRRGIWQVRPVLKN
                     WDHVDFIGIDIFDLKRTGGELAKFYMSIMDNLLHIEALDMAAHIKKSAS"
     gene            complement(5622..7007)
                     /locus_tag="NO87_RS04415"
                     /old_locus_tag="NO87_04415"
     CDS             complement(5622..7007)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614886.1"
                     /locus_tag="NO87_RS04415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_04415"
                     /product="APC family permease"
                     /protein_id="WP_014614886.1"
                     /transl_table=11
                     /translation="MKKLGFWSIVLLSINSIIGSGIFLTPGSVIRISGIYTPLIYVMAA
                     IFASILALTFASASKYVNKSGAAYSYTMVALGPHIGFYVGITRFIAGSIAWGVMATAVV
                     KTVITIFGGDHTDARLITLGFILLMGILLLINVLGKHLLVWVSNLSTIGKIAALLTVII
                     SGLYLVIQTGDTQFSRISTLVDTSQIDSQAFVMAIIAAFYAFTGFESIATGAQDMKSPE
                     KNLPRAIPLAIFMIAFIYIGVISITMTINPVALIQTKEVVSLVAVFDTPVIHRIILYGS
                     LISMFGINVAASFSTPRIIEAIAHEGQIPKWFKKRTVYDFPLPAFMLTFLIAIAIPLAF
                     QYNLTSIILLSSISRFIQYLIVPICVILFYYGKTSAPTLNHIRKNFFTDVLLPIFSFVL
                     TLVLLIKFNWKGQFLITNDAVTSFNYLGVASLVLSYVIFPIILYRLTPLSKKESTQIPR
                     KMT"
     gene            complement(7013..7750)
                     /locus_tag="NO87_RS04420"
                     /old_locus_tag="NO87_04420"
     CDS             complement(7013..7750)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614885.1"
                     /locus_tag="NO87_RS04420"
                     /note="Members of this family of hydrolases with an active
                     site Cys residue belong to MEROPS family C26; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="NO87_04420"
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="WP_250883181.1"
                     /transl_table=11
                     /translation="MGALKLVTVGISANISYDTGGMFPGYERCYVNQDYIHTIVKHHAI
                     PLVLPIHTSQEIISQQIAHIDGLILTGGDDISPSLYHQDPYEKLGRTLLTRDLFDFKLL
                     EAAKRKGIPILGICRGAQIINVYHGGSLYQDLSYREAHTLRHHQKHIPTETTHTIHIEP
                     NSRLADAFETSQIMVNSFHHQTIQTIAPKFKAIAHATDGVIEAIEATNYPYLIGIQWHP
                     EMFWRESLMDRLFSDFIKICESK"
     misc_feature    complement(7729..7745)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.99"
                     /tool="antismash"
     gene            8094..8816
                     /locus_tag="NO87_RS04425"
                     /old_locus_tag="NO87_04425"
     CDS             8094..8816
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614884.1"
                     /locus_tag="NO87_RS04425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_04425"
                     /product="hypothetical protein"
                     /protein_id="WP_014614884.1"
                     /transl_table=11
                     /translation="MKRLAFALFAFLLLLAGCGDKDSKKEEQSSTQNDKTEKTAKQQEK
                     TLENNKKEVADTTNESQQTENKGIDKDTKNNQQETKQKNVQNQSTDKQANVSHSPSHET
                     KKDLNEASRIALVFFGNDIQHYTITKSEILKGQYEYQGAGMTTTKNVNQLTLIHQRDIP
                     NAPSGMKFYTLDPPKGNFATIIGVNQNKVFVGGTQGALVDYQELLTTGKEMNLQSLYEA
                     YKNDPAYTSILNKIKIVN"
     misc_feature    9066..9081
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 24.23"
                     /tool="antismash"
     misc_feature    complement(9068..9082)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.98"
                     /tool="antismash"
     misc_feature    complement(9069..9084)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: strong, score: 29.38"
                     /tool="antismash"
     gene            9149..9991
                     /gene="cntK"
                     /locus_tag="NO87_RS04430"
                     /old_locus_tag="NO87_04430"
     CDS             9149..9991
                     /codon_start=1
                     /gene="cntK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614883.1"
                     /locus_tag="NO87_RS04430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_04430"
                     /product="histidine racemase CntK"
                     /protein_id="WP_250882592.1"
                     /transl_table=11
                     /translation="MIFILKGDGIKLEIVHFSKFNPSGNMTVLVDSQHDPSQYRHIAQQ
                     LMKSSHVGCEQVGFIVDDEGELPHQLVMSGQEFCGNGTLSFIRYLKDRNLLTTSSFKLK
                     VSGMDTPVHCAIHETPQQFETTLPQPEKILERQYKIDDVLFEGLEIQYDTYQHFVFPIT
                     VWSEKLASSIESFVRAEEWPEHLTAVGLMLYDTLHQRLYPLIYVPQIDSIIWEQSCGSG
                     TGSVGVYEAYQNQLEHLEKEIVQPGGALTAIVDHNDEGYQVAIKGNVSTVATGLAYIE"
     gene            10001..10819
                     /gene="cntL"
                     /locus_tag="NO87_RS04435"
                     /old_locus_tag="NO87_04435"
     CDS             10001..10819
                     /codon_start=1
                     /gene="cntL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     opine-like-metallophore: CntL"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019167820.1"
                     /locus_tag="NO87_RS04435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_04435"
                     /product="staphylopine biosynthesis enzyme CntL"
                     /protein_id="WP_014614882.1"
                     /sec_met_domain="CntL (E-value: 1.6e-92, bitscore: 303.5,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKIQQNTHEIEAQLKHYQQQFEHLYHNIQQGERALNDLERLIDE
                     YSSYILDEQPKQQYEHWRSQTTEQQHLIKPLADITAKCVKLMESSRARRLIHGEHGTTG
                     YFDNIEHCISEEFGQFEITSEDTVLLVGSGAYPMTLVQIAKETGARVIGIDIDEEAVRY
                     GQQVIRILAPDAPIEIHQATVSELEGIQNVTHVIFSSTVEMKYDILEELYHLTGHDIVV
                     SMRYGDGLKSIFNYPKQETHPQQWTFVDDITRPDQIFDIALYQKKSEGRA"
     gene            10822..12117
                     /gene="cntM"
                     /locus_tag="NO87_RS04440"
                     /old_locus_tag="NO87_04440"
     CDS             10822..12117
                     /codon_start=1
                     /gene="cntM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     opine-like-metallophore: CntM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614881.1"
                     /locus_tag="NO87_RS04440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_04440"
                     /product="staphylopine biosynthesis dehydrogenase"
                     /protein_id="WP_063284555.1"
                     /sec_met_domain="CntM (E-value: 1.3e-158, bitscore: 522.0,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKSVLIAGTGPVAVQLAVLFKTYTTHHVDMVGRSDVSAKAQQFW
                     QAYQNAQQLEVQVQNDLHMSLAGTATLGRLYERYEAVEPHYDVLVLACTADAYSQVIQQ
                     LSPAVRQQLKHVVLVSPTFGSHMVVQQQFSAEQPNIEVISFSTYLGDTTVSHPETPHRV
                     LTKGIKKHLYIGTIYEQSDFSQEIIDLLSEVQIPVTQVAHPLMAESRNSSLYVHPALFM
                     NKHALKAVFEGMTVPFYVYKLFPEGPITMQLIAEMRQMWQEVMAILKHLNIDTLNLLKF
                     MVKENYPLRPETMDDDRIEAFETLSAIEQEYLLYIRYTGILIDPFSEPDENGKYFDFSA
                     VPFKEVFRNEEGVWQIPRMPNEDYYRTQMMRGIAQALNISTPMMDTLIQRYEAQLTAFQ
                     KAHPNDRVSTQFQIQSFEEDINSIAKLLNSEG"
     misc_feature    complement(10851..10865)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 18.17"
                     /tool="antismash"
     gene            12352..13953
                     /gene="nikA"
                     /locus_tag="NO87_RS04445"
                     /old_locus_tag="NO87_04445"
     CDS             12352..13953
                     /EC_number="7.2.2.-"
                     /GO_component="GO:0009897 - external side of plasma
                     membrane [Evidence IEA]"
                     /GO_component="GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015413 - ABC-type nickel transporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0015675 - nickel cation transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="nikA"
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015728547.1"
                     /locus_tag="NO87_RS04445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_04445"
                     /product="nickel ABC transporter substrate-binding protein"
                     /protein_id="WP_014614880.1"
                     /transl_table=11
                     /translation="MMMKNLKWIAVSIVMLLVLAACGNSKALEQKKEDKNLTYATSKDI
                     GDMNPHVYGGSMSAQGMVYESLVDHTQKGIEPLLAESWDVSEDGKTYTFHLRKGVKFQD
                     GTPFNADAVKKNFDAIQANQKLHSWIKLSTLIDRTEAKDDHTFVMTLKEPYNATLEELA
                     MTRPYVFVSPKSFKAEGTKDGLKSYVGTGPYQLKSHDKDEQATFERNEDYWGGKPHLKT
                     IVAKVLPAGETSFLALQKGEVNFAFTDDRGTDNIDNEAMKKLTDNGDFQLKRSQPMNTK
                     MIVANSGKKDSPAQDKAVREALWYSVDQKRIADKILEGTEKPASQLFSKNVPHANIDLP
                     KRDFDLKKAAALLDEAGWKQNDKGEVREKDGQKLEMTLYYDNHSSSQKQEAEFIQAKAK
                     EIGMALKIVGETSDKVAERRTSGDYDLLFNQTWGLQYDPQSTISGFKADTGYKAAVSGI
                     KEKDQLFDDIDTALKTQDAKEQDQKYKDILTTVHDEAIFIPISHGGMTVVAPKDLEHIS
                     FKQSQYELPFEQMDYK"
     gene            13966..14898
                     /gene="opp1B"
                     /locus_tag="NO87_RS04450"
                     /old_locus_tag="NO87_04450"
     CDS             13966..14898
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="opp1B"
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015728548.1"
                     /locus_tag="NO87_RS04450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_04450"
                     /product="nickel/cobalt ABC transporter permease"
                     /protein_id="WP_015728548.1"
                     /transl_table=11
                     /translation="MAYSAMKRLLLMIPLLIVISFLTFALTHLSSEDPAVVILHAQEVP
                     DITQSLIEQTRAKYHLDAPFLVQYWEWLQSAVQLQFGHSFVTGEDVGLRLWPAFFNTLK
                     LTLISSVAIIVLSLLFGILTALLRGTWFDRMTRTTAFVLTAIPSYWLAAILIIFLSVKL
                     NALPTSGLTGPESYILPVAVITLGYTGIYFRNVRSAVIQQLDQDYVLYMRAMGVPMSQL
                     LVYVARNAMQVVVSIFCMSIPIILGGSVVIENVFAWPGMGQLSVKAVLEQDFPMIQAYV
                     LIVSVLFILFNTLADVINMWLNPKLREEH"
     misc_feature    13983..13996
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 20.2"
                     /tool="antismash"
     gene            14900..15763
                     /gene="opp1C"
                     /locus_tag="NO87_RS04455"
                     /old_locus_tag="NO87_04455"
     CDS             14900..15763
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="opp1C"
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614878.1"
                     /locus_tag="NO87_RS04455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_04455"
                     /product="nickel/cobalt ABC transporter permease"
                     /protein_id="WP_063284556.1"
                     /transl_table=11
                     /translation="MIVFQRLLNDNGAKWALAIIAVYILLGIFAPIVTPYDPNTVNIDD
                     KFAGMSFAHWLGTDHLGRDILTRLIFAIRPSFLLILFALACSVLIGTLLGFISGYFGRW
                     VDALVMRICDVMLSFPTYVMTLALIGVLGIGLKSIIVALIITRWAWFCRIIRTSVMQYR
                     NSDDVKFARTIGLSHARIIMTHILPRTLADIAIISTSSMVSMILQISGFSFLGLGVKAP
                     TAEWGMMMNEARKVMFSHPELMFAPGIAIIVIVLAVNFLSDALQIAIDPKLSQQQMKQR
                     IKKGWI"
     gene            15763..16581
                     /locus_tag="NO87_RS04460"
                     /old_locus_tag="NO87_04460"
     CDS             15763..16581
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019168634.1"
                     /locus_tag="NO87_RS04460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_04460"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_014614877.1"
                     /transl_table=11
                     /translation="MVEQLMRVEDLTLIDGHTNHVLVHHFNLTLHRGEVIAIIGESGSG
                     KSMTCKALLGLNDRNIRMSGEIWFQEEALHNASEADFRKIRGRRIAMIMQQGATAFNPS
                     FTVGAQLTMMLKQHRPMSTQQQKATLQHYFDMLGLRDFERILKSYPHQLSGGMLQRLMI
                     ILALALQPDIIIADEPTTALDAITQYEVIEELREVKEKIGCAMIFVSHDLAVVKSIADQ
                     VIVMRNGDVVEAGPAHQLFTAPQHAYTQFLIAARDRVTRYYKSLRGDASC"
     gene            16575..17315
                     /locus_tag="NO87_RS04465"
                     /old_locus_tag="NO87_04465"
     CDS             16575..17315
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614876.1"
                     /locus_tag="NO87_RS04465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_04465"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_014614876.1"
                     /transl_table=11
                     /translation="MLEVQNVTKSYRSGVKRQKRQIVKQVSFQCSKGQSIAIIGESGSG
                     KSTLARMILGIEKPDTGTVMLDGQPVCQRHTRLGKMSVVFQDYKSSLHPYFNVRQILNE
                     ALSQCDTPVDDKEAHMTALLERVGLSAAFLNKYPQMMSGGEAQRVAIARAVITNPDYIV
                     LDEAISALDMSIQSQILDLLTTLRDKYQLSLIFITHDIQAAVYLCEDLIIFNDGQIQER
                     LNRHQLKTLQNDYTRELFEKQFMN"
     gene            17327..18517
                     /locus_tag="NO87_RS04470"
                     /old_locus_tag="NO87_04470"
     CDS             17327..18517
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614875.1"
                     /locus_tag="NO87_RS04470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_04470"
                     /product="MFS transporter"
                     /protein_id="WP_014614875.1"
                     /transl_table=11
                     /translation="MKGALAWPFLRLYILALFFFSANAILNVMIPLRGHDLGATNATIG
                     IVMGAYMLTAMLFRPWAGQVIAKVGPIKILRWILIINGFALILYGFTGLEGYFIARVMQ
                     GVCTAFFSMSLQIGIIDALPEEDRSQGISLYSLFSYIPGIIGPMIAVGIWQLDNLSYFA
                     LTMIIIAITTGVVGFSATLHGHDDADTTPAQQEKMPYGAMTVFLQLFKNPFLLKAGTIM
                     LVASIGFGAVATFIVLYVNKYQVGHASLFLAVQAITVVFARFFLRQYIPSDGRWHVRFM
                     LGVLGLLTVALLFIAIGPYVGGWILYISAVMIGLTQAMVYPTLTSFLSFKLPKVGRNML
                     LGLFIATADLGVSLGAALMGPIADMVGYANMYLICGILMAFITLMSIERRPQFIEK"
     gene            complement(18711..19139)
                     /locus_tag="NO87_RS04475"
                     /old_locus_tag="NO87_04475"
     CDS             complement(18711..19139)
                     /EC_number="1.14.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614873.1"
                     /locus_tag="NO87_RS04475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_04475"
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="WP_014614873.1"
                     /transl_table=11
                     /translation="MILSHKDFLYQIEEDGTTVTIYKNNDTKTYTAIEATGELTPHHFC
                     VLNYIKVDLNQSETFEERFLSRTADLNDVHGFISLRVLRPWDPQNHYVVISLWDDRKSF
                     EVWQASEQPLNYHHQWNGALDEEIVNSDLSYYIKFDAQ"
     gene            complement(19383..20555)
                     /locus_tag="NO87_RS04480"
                     /old_locus_tag="NO87_04480"
     CDS             complement(19383..20555)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614872.1"
                     /locus_tag="NO87_RS04480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_04480"
                     /product="MFS transporter"
                     /protein_id="WP_014614872.1"
                     /transl_table=11
                     /translation="MKKYPIAIWMLAIGAFAIGMTEFVIMGLLPNVANDLNVSVSQAGQ
                     LITGYALGVAIGGPIIVMLTFRLNRKALLMLLMGIFILGNILGGLSPNYTTLMLSRIVT
                     SLAHGSFFGIGSILAASMVASQYRASAMALMFMGLSLSNILGVPFGTLIGQKLGWHMTF
                     LIIAVIGVIALIGIMMFVPMPKEMRTASIKDELRILKEKRLWLTLGMTLFGFSSVFAYF
                     TYISSVLIDVTHIPEQFISSILIVFGVGVTLGNIVGGKLADWNLNKALMSIFIIFVLYF
                     GLLYFIQFHPIIMVIGVFLFGFIGFSMSPSLQYKSTLISQEAPTLSSTLNQSAFNIGNA
                     LGAFIGGLVVSTLPIASLSLIAPLLTLIGLVFLLWSIAVEQKEQVNTHSN"
     gene            complement(20748..21497)
                     /locus_tag="NO87_RS04485"
                     /old_locus_tag="NO87_04485"
     CDS             complement(20748..21497)
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015728549.1"
                     /locus_tag="NO87_RS04485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_04485"
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_014614871.1"
                     /transl_table=11
                     /translation="MLYIFLSLLGIIGGILSGMVGIGGAIIIYPALLIIPPMLGLPSYN
                     AYIASGLTSAQVFFSTLSSSIRARQTPDFSLKLILWMGSSMLIGSALGATIAEVLTERF
                     VNSVYVVIAILALVLIMIKIKPQTEANLKFSKVVLLLTGLVIGAISGVIGAGGAFIIIP
                     VLLVFFKIPMHTVVANSVVIAFISSIGAFMFKLFQGYIPLGDALFLVVGSMLFAPLGLK
                     IGRQMPEYVQKVLVALLIIVSILNLIF"
     gene            complement(21497..21757)
                     /gene="cstR"
                     /locus_tag="NO87_RS04490"
                     /old_locus_tag="NO87_04490"
     CDS             complement(21497..21757)
                     /codon_start=1
                     /gene="cstR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016911203.1"
                     /locus_tag="NO87_RS04490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NO87_04490"
                     /product="persulfide-sensing transcriptional repressor
                     CstR"
                     /protein_id="WP_014614870.1"
                     /transl_table=11
                     /translation="MEYDKKMINRIKRVQGQLNGVIKMMEEEQHCKDIVTQLSASKGSL
                     QRLISIIISENLVECIKAAEENEENRQQIIDEAVNLLVKSK"
     misc_feature    21864..21880
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.07"
                     /tool="antismash"
ORIGIN
        1 accataatac atataagaga tgactgagga attgacgtca tattctaaaa caagtgatga
       61 gcaatgcaat caagatgtct attgggggag gaaataaaaa cggtttattt taacacaata
      121 tttttatagc tgtagacaaa aagacatcta gagactctga catgttaaag tcaaaatttc
      181 tagatgatta tgattaggtt taatgatgat gggcatatga gtttataaac gttgagaatg
      241 aaaacaacaa tgatagatat gagatgaaat aaataataaa gtatagtaca agaaatatat
      301 tgaaaataat gtgtataact tggcatttaa gatacggcac cttttgatat gtttataaat
      361 aatacgtttt cctatatgat gttcgtcata aaaaagctta ccaacaaaat gtgtcatcat
      421 aatgagcaga atagtaaact gtgattgtgc gataacgatg ccataataat gccaatcctt
      481 tgtgagtagc cctatttgta taaaatgagt gagttggaag agggtgtgtg aggttcactt
      541 taggaggcat ctatattatt aatatgtaca aataaacaag cgaaaaaact aaaatccctg
      601 aacgttagat gccgtacttt taattaatag ttaataatca gttaataaca tttatttcat
      661 taatatatta aagtatataa agaatgaata agtagaagag cgaggataac aatgttaaga
      721 acaaattata aactaagaaa gcttaaagta ggtttagtat cgacaggtgt ggcgttgact
      781 tttgtgatgg caagtgggaa tgcagaggcg tcggagaacg agcagactga agtaaaaggg
      841 gaggcgcaag ttgcttctgt gaatgaaaaa gagagtgaag cagaattacc tgtagcgcaa
      901 caagaagcat ctattcaact agacaaagta caaccaggcg atgcacagct ttcaggctat
      961 acacagccaa acaaagcgat ttctgtaaag atcgacaata aagatattgt gtctgtagat
     1021 gatggctatg aagaggtatt atcggatgat acaggtaaat ttgtatatga tttgaaaggg
     1081 cgtcaaattg tttacaatca aaaagttgat gttgaagcga tgacgccatt taattttgaa
     1141 gattttgatg aatcagcact tgagagcgaa gaggcattgg aggcgttagg tcaattggaa
     1201 gacgaagaaa cagcgacagc ttctgtgacg acgcctagat atgaaggtgc gtatacagtt
     1261 cctgaagaac gcttgacgcc cattcaaggc caacagcaag tattcatcga acctatttta
     1321 gaaggggcaa gtaaaatcaa aggacataca tctgtacaag gtaaagtcgc gttagcaatc
     1381 aatcaagaac atgtgcacct aggtgatacg ttagaagaac aagcagcact cactggtcaa
     1441 gagtggcaag gtcgttatga cgggatttgg cgccatattg atgatcaagg gtttttcgag
     1501 tttgacttga accgtcttta caataaatct tacccattga agtctggcga tttagtgact
     1561 ttatctttta aatctaatga cgaagtaggc ccattattca atgtgaacgt tgagcctttc
     1621 gaacgtgtgg cacaagctaa aacaaagtat gagcagaatg acagtccagt agtcaacaaa
     1681 ttggatgata ctaaaagtga cttggaggtt caacctatct atggagacct tacacaagca
     1741 gcagtacatg gcgagtcgaa agtgttgata ccggggacgt caaaagttga aggacgtacg
     1801 aattatgcac atgcatggat agagatggca tctaatttag gggaatatcg tagtttccct
     1861 acattacaag ctgatgcgac aggtgcgttt atatttgatt taaaagcggc agacatacaa
     1921 ttgttaaacg gagaacgttt gacattcaga gccgttgacc cacatacaaa acaacagtta
     1981 gctgaaacta catcagaagt acgcccagta gatatgcaag atgaagagtc agaggttgtg
     2041 cagacttcaa gcactgagaa atcagcactt gcggatgaaa ttcttcgttc tatgacaatt
     2101 gacaaatcat ttaatcctga agttaccgag ataccgggtc atgtatatcc taagaaaaca
     2161 gaggataaag gtcctgaaaa tacagaacaa gcctcagaga attctgagaa gccatctcag
     2221 actacagaat ctcaaaatga tgccgtacaa gatgtagaga aatcctctgt taatgaggag
     2281 gttacgccac cttcaacaga atctgctcaa gttgaaaagg ggcaaaatac agaaggggct
     2341 ttgcttccaa aaaatgtaga acaacatgta gagagtatac cataccaaaa acgtaaagcg
     2401 ttgataggac tgacaaaaca tcaaggatca gggcacatgc cgccattttc tttaagcttt
     2461 aacaataaag aagatgacgt atcaacaaag gttaatgaag caaacgagca tgaacgtaag
     2521 cagggtacag tttatccaga gcaaatagaa caattacctc aaacaggttt aactgaaaaa
     2581 tcgccattct gggcattgtt atttgttgta tcaggcacag gtttattatt attcaaacgt
     2641 tctagacgac aacgccaatc ttaatagttg aaaataatgt tatcatactg gatgtgttag
     2701 catatggatt gtattaaatg actctactgt gaaagtagcc atgcaccatc atcagaaaac
     2761 agtatagtgt aacaaaaatc tatagaacaa ttatcaagcg aaaacaatac gaggttttcg
     2821 cttgtttgat tttatgaatt gtatactttt gcggttggtg gggcatctac tgaccgcatt
     2881 ttatttttga tataaaaaac acaaaaccgc tatcattgta attttcaaac caataaagaa
     2941 gatattgtgc ttatgtacaa tatgtaatga tattgaagaa agacagagaa ttaaagttaa
     3001 aaactactta aaaattgggg taacatgcac atcaaaacgt aatggcctat gatgcaaaga
     3061 ttaagataag cgcatgtttg acaactataa aaatgggcag ttaaatccaa ttgatgattg
     3121 agacaactaa gggaagcaat aaaacatagt acctaaaata tagactaaaa tctttaaccc
     3181 tttatcagat attctgtaaa ttaataaatt ttaaatataa ttttatgata ctatatatat
     3241 ttataactaa tgtgatatat tatcattaca gttgtttaag ggggatttaa ttaaggggag
     3301 ttaatcttat tagaggtgat atcatgaatc aatacaatca aaaaagtatt tatcgtatca
     3361 gaaagtatac tgtaggtgtg gtttcagtct tggcgacgat gaccttctta atcggtgggc
     3421 atgacgctat ggcaagtgag cagcatacta ctcaagcatc tagtgaatta gcgagaacag
     3481 aagtgactgt aagcaatcag tcgctaagtg aagacactca tacacagtcg ttatctcaaa
     3541 aagaaggaca acattctcat tcaggtgact ctaaaaatcc taaaacatcg ctattcgcta
     3601 acgcttcatc tcaagagcaa ttgcctacta caccggagca aggtgtttca tcggataatc
     3661 ctaacacgtc tcatcccact catatcaatg aaaatacaaa tgtcccttct ttagttgaca
     3721 tacaacaaga gaagggggaa aaattaagtg atgttccaaa cagcgagaaa gtgaagacgc
     3781 aatcaggtag tcagattgag gcacctcctc attcaaacag ccgtaaagcc gggcgtattg
     3841 cagaaaacca ggatttaaca tctcagcaaa gtgatgtggc attaaaagac caatcagatg
     3901 ttgaagtgag caaacgtgtg aaccatcgat cttctgaagc tatgcgggct cgaaatgtag
     3961 aaaaagcaca gacagatgaa atcgatcaaa tgacatcaca gaatcttaaa ccagttgtta
     4021 aggataaaac tgatcaaggt aaagagcaag ctatagcaga acacaaagat caaactaaaa
     4081 aaggcgcttc agaagaggaa atgacgcaaa aggaaacaac acaagaacag caatcccaaa
     4141 cgcgtgtagc gaattctaaa gaggtgttag aaaaatcatc cactcaagct cagcaaaagc
     4201 aatctaccaa taaatatcct atcgtgttag tacatggatt tttagggtta gtaggtgaaa
     4261 atgcaccagc actctatccg aattattggg gaggcaataa atttaaagtt attgaagcgt
     4321 tgaggaagaa aggctacgat atacaccaag caagtgttgg tgcatttagt agcaattatg
     4381 cacgtgcagt ggatttatat tattttatca aaggcggtcg tgttgattat ggtgcagcac
     4441 atgcagctca atatggtcac gaacgctttg gtaagattta taaaggaatt atgcctgact
     4501 ggagaccagg taaaaaagtt catttaattg ggcatagtat gggaggacag acggttcgtt
     4561 taatggaaga acttttaagg aatggtagca aagatgaaat tgcgtatcac caaaaacatg
     4621 gtggtacaat ttcgccactt tttaaaggag ggctcactga tatggtttca tcaataacga
     4681 cactcgggac ccctcataat ggctcacaag ctgcagatca agtggcaaat aaagaatttg
     4741 tacgccatat catgtacgca ctgagtcggg tggcaggtag cgaatattca gactttgact
     4801 taggtttaag gcattggggc tttaagcaaa gacctggtga aagttacttt gattatatga
     4861 agcgtgtgag tgaaagccca atttggcaaa cgaaagataa cgcggcctat gatttaacat
     4921 tagaaggatc ggcaatttta aatcagaaaa caagcctaaa ccctaatatt acatacacga
     4981 cttatactgc tgaagcatcg cataaagggg cttcggggaa agaggttcct aatgtgggcg
     5041 tgtttccgtt aatggattta acgagtcgca ttattggcag tgatgctagg ttagagtggc
     5101 gtaaaaatga tggggttgtt gcagttattt catcactatt tccattaaac caaccttttg
     5161 ttaaggtctc atctgatgct ttagcgaccc gtagagggat ttggcaggtc agacctgttt
     5221 taaaaaattg ggaccatgtt gattttattg gtattgatat tttcgattta aagcgaacag
     5281 gtggagaact agcgaaattt tatatgagta tcatggataa tttattgcat attgaagcgt
     5341 tagatatggc cgctcatata aaaaaatctg catcttaatc cattgtatta ggtttgagta
     5401 accgaatatc gtcacatatc gcgttcactt taaaagtttt aatggagtaa acaaaaacat
     5461 ctgcatcgat taaatgacga ataagtcact actgcttgat gaagcggaat gacagttaga
     5521 gacgtgcgct tgtgatgtat agcatgagaa ggagtggtac gttaaagcga taattaatga
     5581 agttttttcg tcccactcct tatatttttc aatcgtccat tttaggtcat cttacgtggt
     5641 atttgagtcg actctttttt acttagaggt gtcaaacgat aaagtattat tgggaaaatg
     5701 acgtaactca aaactaatga ggcaacaccc aaatagttaa aagatgttac agcgtcgttt
     5761 gtaataagaa actgcccttt ccaattgaat tttataagta aaacgagtgt caatacaaaa
     5821 gaaaatatag gtaacaatac atccgtaaag aaatttttac gaatatgatt tagtgtaggt
     5881 gcactcgttt tgccgtagta aaataaaata acacagattg gaacgattaa atattgaatg
     5941 aacctagaaa ttgaacttaa aagaatgata cttgtcaagt tatattgaaa agccaaaggt
     6001 atagcaatag cgattaagaa tgtcagcata aatgcaggaa gcggaaaatc atagacagta
     6061 cgttttttaa accatttcgg gatttggcct tcatgggcga tagcttcaat aattcttggc
     6121 gttgaaaaag aagcagcgac attaatacca aacatggata ttaagcttcc atacaaaatg
     6181 atacgatgga taacaggtgt atcaaatacg gccaccaatg agacaacttc tttggtttga
     6241 atgagcgcca ctggattgat agtcatagtg atggaaataa ccccaatata aatgaatgca
     6301 atcatgaaaa tagctagcgg aatggctctg ggtaagtttt tttctggaga tttcatatct
     6361 tgtgcgcccg tagcaatact ttcaaatcct gtaaaagcat agaaagcggc tatgatggcc
     6421 ataacaaatg cttgtgaatc gatttgagaa gtgtcgacaa gtgtactgat acgactaaac
     6481 tgggtatcac ctgtttgaat aactaaatag agacctgata tgataacggt aagtaaagca
     6541 gctatttttc caatcgtgga gaggttgctg acccagacta aaaggtgttt gccgagtaca
     6601 ttaatgagta acaaaattcc cattagcaaa ataaagccca acgtgataag acgtgcatcc
     6661 gtatgatccc caccaaaaat agtgatgaca gttttaacga cagctgtcgc catgactccc
     6721 catgcaatac tcccagcaat aaaacgcgta atccctacat aaaatccgat atgaggacct
     6781 aaagccacca ttgtataaga ataggcagcg ccacttttat ttacatattt tgaagcagat
     6841 gcaaaagtga gcgctaaaat actagcaaat atagcagcca tgacatatat cagtggcgta
     6901 tagatccctg atattcgaat gactgatccg ggagttaaaa agataccaga accgataatt
     6961 gaattgatag ataataatac gatagaccag aagcctaatt ttttcataca tatcacttac
     7021 tttcacatat tttaataaaa tctgaaaaca gtcgatccat caaactttct ctccaaaaca
     7081 tttcagggtg ccattgaata ccgattaaat aaggatagtt tgtagcttca atagcttcaa
     7141 taaccccatc agttgcatgg gcaatggcct taaatttggg ggcgattgtt tgaatagttt
     7201 gatgatgaaa tgagttaacc atgatctgag aagtttcaaa tgcatcagcg agtcgagaat
     7261 tgggttcgat atgaatggta tgcgtcgttt cagtaggtat gtgtttttga tgatggcgta
     7321 acgtatgtgc ttcacgatag gataaatctt gatataagct tcctccgtgg taaacattaa
     7381 tgatttgtgc accacgacaa atacctaaaa ttggaatacc tttacgctta gcagcttcaa
     7441 gtaacttaaa gtcaaataaa tcacgtgtta aaagcgttct gccaagcttc tcataaggat
     7501 cttgatggta tagagatggg ctaatatcat caccaccagt taagattaaa ccgtctatat
     7561 gtgcaatctg ttgtgaaatt atttcttgtg aagtgtgaat cggtaaaact aagggtatgg
     7621 catgatgctt aacaatggta tgaatataat cttgattgac gtagcaacgt tcatatccgg
     7681 gaaacattcc tcccgtatcg tatgaaatgt tagctgatat acctactgtg accaatttta
     7741 atgcacccac tatctataat aatattttta agtatcatat aaaacatagt aaatgtcaat
     7801 attaaacagg agttatcttt aaaagtgtca tgttattata tgagtgactt aaaccgcata
     7861 tttaatcaat gttccgttaa agggcgtatg attaaaaagg acatctatta aaaaattgaa
     7921 tgagtgatgt aaacagctaa tgccattaaa gttttactaa agtgttttgc tataaaatat
     7981 gtatatttac tacatatatt tttctataag tctatggacc tattgtgtat agaaaaatat
     8041 ttgatatatt tataagtaga tagtaaaaaa tgtacttaaa tgaggtgttg aatatgaaaa
     8101 gattagcttt tgcgctcttt gcttttttac ttttattagc tggttgtggg gataaagatt
     8161 caaaaaaaga agaacaatca tcgacacaaa atgataagac agaaaaaacg gcaaaacaac
     8221 aagaaaaaac gttagagaat aataagaaag aagtggcaga cacaaccaat gagtcacagc
     8281 aaacagaaaa taaaggaatc gataaagata ctaaaaacaa tcagcaagag acaaaacaga
     8341 agaatgtaca aaatcaaagc actgataaac aagctaatgt gagtcattca ccttctcatg
     8401 agacaaagaa agatttgaac gaagcatcta gaattgcact cgtatttttt ggcaatgata
     8461 tccaacacta tacaataacg aagtcagaaa ttctaaaagg tcaatatgaa tatcaaggtg
     8521 ctgggatgac cactacaaag aatgttaatc aattaacatt aatccatcaa agagacatac
     8581 ctaacgcgcc atcaggtatg aaattttata ctttagatcc tccaaaagga aattttgcga
     8641 caattattgg tgtaaatcaa aacaaagtat ttgtaggtgg gacacaaggt gcgttggtag
     8701 attaccaaga gttgctcact acaggtaaag aaatgaattt acaaagtttg tacgaagcgt
     8761 ataaaaatga tccagcatat acgagtattc taaataagat taaaatagta aattaatagt
     8821 atgtatatat taaaacgggc tgtgaaaata tccatcacaa aagatgattt cacagctcgt
     8881 tttaatgtgt ttttacatgt tcaaacacag cttctgttaa tgtttcgcaa cgactttaaa
     8941 aatgtatctt aaattatgat gattcagcgg tctttgtacg atgacatcat tacaatggct
     9001 gactattaat aggaattttt agaagtagat atttagagat gaagatggat aataaaaagt
     9061 aaagttttga taatgattat cattgttgac atttcaaaaa tttgagagta ggatattttt
     9121 aaatcgttat gattacgatt tgtaattaat gatatttatt ttaaaaggag atggaataaa
     9181 attggaaatt gttcattttt caaaattcaa tccatctgga aatatgactg ttttagtgga
     9241 ttcacaacat gaccctagcc aatataggca catcgcccag caacttatga aaagttcaca
     9301 tgtgggttgt gaacaagtcg gatttattgt agatgatgaa ggtgagctac cacatcaact
     9361 tgtgatgagt ggccaagaat tttgcgggaa tgggactttg tcatttattc gttatttgaa
     9421 ggatagaaat ttactaacga cgtcctcttt taaattgaag gtatccggaa tggacacgcc
     9481 tgttcattgt gcgatacatg aaacacctca acaatttgaa acgacgctcc cacaaccaga
     9541 aaaaatatta gaaagacaat ataagattga tgatgtcttg tttgaagggt tggaaattca
     9601 atatgataca tatcaacact ttgtattccc aattacagtg tggtcagaaa agctagcctc
     9661 ctctatcgaa tcgtttgtta gagccgaaga atggccagaa catctgacgg ctgttgggtt
     9721 gatgttatat gatacactgc atcagcgctt gtatcccctc atctatgtgc cacagataga
     9781 tagcatcata tgggagcaaa gttgtgggtc aggaacgggt tcggtaggtg tctatgaagc
     9841 gtatcaaaac cagttagaac atttagaaaa agaaattgta caacctggag gtgcgttgac
     9901 tgccattgtt gatcacaatg atgagggcta tcaagttgca atcaaaggaa atgtttcaac
     9961 ggttgccaca ggtttagcat acatagaata ggagtacgtg atgaataaaa tacaacagaa
    10021 cacacatgaa attgaagcgc aattaaaaca ttaccaacag caattcgaac acctttatca
    10081 taacattcaa caaggcgaac gtgcacttaa tgatttggaa cgcttaattg atgaatatag
    10141 cagttatata ttggatgaac agcccaagca acagtatgag cattggcgga gtcagactac
    10201 agaacagcag catcttatta aaccactagc agatattact gcaaaatgcg ttaaattgat
    10261 ggagtcctct cgagcacgcc gtttgattca tggtgagcat gggacgacag gatattttga
    10321 caatattgaa cattgcattt cggaagaatt tggacagttt gaaattacat ctgaagatac
    10381 agtgctatta gtaggatcag gtgcgtaccc tatgacttta gttcaaattg caaaagaaac
    10441 aggcgcacgt gtcattggaa ttgatattga tgaagaagcg gtgcgctatg gacaacaagt
    10501 cattcgcatt ttagccccag atgcgccaat agaaatacat caagcaacag tatccgaact
    10561 agaaggaatt caaaatgtca cacatgtcat cttcagctca acggtcgaaa tgaaatacga
    10621 cattttagaa gaactttatc accttaccgg tcatgacatt gtggtgtcta tgcgttatgg
    10681 tgatggcttg aaatctatat ttaattatcc taaacaagag acacatccgc agcagtggac
    10741 ttttgtagat gacattacac gtccggatca aatctttgat attgcactct accaaaaaaa
    10801 atcagaaggg cgtgcataat aatgaaaaaa tctgtcttaa ttgcagggac aggtccggtc
    10861 gccgtgcagc ttgcagtgtt attcaagacc tatacaacac atcatgtaga tatggtgggg
    10921 cgaagtgacg tttcagcaaa ggcacaacag ttttggcaag cataccaaaa tgcacagcaa
    10981 cttgaagtac aagttcaaaa tgacttgcat atgtcgttag caggtactgc aacacttgga
    11041 cgattgtatg agcgttatga agcagtcgag ccacattatg atgtgctcgt gcttgcatgt
    11101 actgccgatg catacagtca ggttatacaa cagttgtctc cagctgtacg tcaacaactc
    11161 aaacatgtcg tgcttgtttc tcctacgttt ggttctcata tggtcgtcca acagcagttt
    11221 agtgcagaac agccgaatat tgaagtgatt tcattttcta catatttagg tgatacgact
    11281 gtatcgcatc ctgaaacacc acatcgtgta ctgacaaaag gaataaaaaa acatttgtat
    11341 atcggtacaa tatatgaaca atctgacttt tcccaggaaa taatagattt gttatctgaa
    11401 gttcaaattc cagtgacgca agttgcccat ccactcatgg cagagtcgcg aaacagctca
    11461 ctttatgtgc atccagcgtt atttatgaat aaacatgctt tgaaagcagt gtttgaagga
    11521 atgaccgtac cattttatgt atacaaatta tttccagaag gtcctattac gatgcagtta
    11581 atcgctgaaa tgcgacaaat gtggcaagaa gttatggcga tattgaaaca tttaaatatc
    11641 gatacgttaa atctattgaa atttatggtg aaagaaaatt acccccttcg ccctgaaacg
    11701 atggatgatg atcggattga agcgtttgaa acactttcag ccatcgagca agaatattta
    11761 ttatacatac gttataccgg tattttaatt gatccgtttt cagagccaga tgaaaatggt
    11821 aagtattttg atttttcagc agttcctttt aaagaagttt ttcgaaatga ggaaggtgtt
    11881 tggcaaattc ctcgcatgcc gaacgaagac tattaccgta cacaaatgat gcgaggtata
    11941 gcacaagcat tgaacatctc cacgccaatg atggatacat tgattcaacg ctatgaagca
    12001 caactgacgg catttcaaaa agcacatcct aatgatcgtg tatccacgca atttcaaata
    12061 cagtcgttcg aggaagatat caacagtatc gctaaattat tgaactctga aggataaagg
    12121 gaatgtgtta agttcattga ttggatgaaa ctccattttg agaaccagta aaatgactgt
    12181 gaaacaaaat tcaactatga agtgactgga ttgataaaag tgttcaaggt gggtcatcat
    12241 gagtacccat tgacactgat atttatacgc taaagaaaat caagcaaatt taacaatgtg
    12301 tactaaaaat gctagcacta ctgaaagaaa tgagataaag agaggatatg aatgatgatg
    12361 aaaaatttaa agtggattgc cgtaagtata gtaatgttac ttgtacttgc agcctgtggt
    12421 aactctaaag cattagagca gaaaaaagaa gataaaaatc ttacatatgc cacatcgaaa
    12481 gatattgggg atatgaaccc gcatgtatac ggtgggtcaa tgtcagcaca aggtatggtc
    12541 tatgaatcat tagttgatca tacacaaaaa gggattgaac cgttattagc tgaatcttgg
    12601 gacgtatcgg aagatggaaa aacctacaca tttcacttaa gaaaaggtgt aaaattccaa
    12661 gatgggacac cgtttaatgc agacgccgtg aaaaagaact ttgatgctat tcaagcaaat
    12721 caaaaattac attcttggat taaattatca acattaatcg accgtacaga agcaaaagat
    12781 gatcatacct ttgtgatgac tttgaaggag ccatacaacg caacgttgga agaactagcc
    12841 atgacacgac cttacgtttt tgtctcacca aaatcattta aagcagaggg tacaaaagat
    12901 ggtttgaaat cttatgttgg tacaggtcca tatcaattaa agtcacatga taaagatgag
    12961 caagcgacat ttgaacgtaa tgaagattat tggggtggca aaccacattt gaaaacgata
    13021 gtcgctaaag tattaccagc aggtgaaaca tcatttttag cgttacaaaa aggtgaagtg
    13081 aactttgcgt ttacggatga ccgtggtaca gataacatcg acaatgaagc aatgaaaaaa
    13141 ttaacagaca atggcgattt ccaattgaag cgcagtcaac cgatgaatac gaaaatgatt
    13201 gttgcaaact ctggtaaaaa agacagccct gcacaagata aagcggtgcg tgaagcattg
    13261 tggtatagcg tcgatcaaaa gcgtattgcg gacaaaattt tagagggtac tgaaaagcct
    13321 gcgtcacaat tattctcgaa aaacgtgccg catgcgaaca ttgatttacc aaaacgtgat
    13381 tttgatttga aaaaagcagc ggcgctatta gacgaagcgg gatggaagca aaatgacaaa
    13441 ggtgaagtgc gtgaaaaaga cggtcaaaag cttgagatga cgttatatta cgacaaccat
    13501 tcaagctcgc aaaaacaaga agctgaattt attcaagcga aagcgaaaga aattggtatg
    13561 gcattgaaaa ttgtaggaga aacatctgat aaagtggcag agcgccgtac atcaggtgat
    13621 tatgacttac tgtttaacca aacatggggt cttcagtatg atccacaaag cacgatttct
    13681 ggctttaaag cagatacagg ttataaagca gccgtttcag gtatcaaaga aaaagaccaa
    13741 ctgtttgatg acattgatac agctttaaaa acacaagatg caaaagagca agaccaaaag
    13801 tataaagaca ttttaacaac agtacatgat gaagcaatct ttattccgat ttctcacgga
    13861 ggtatgacag ttgtcgctcc gaaagattta gaacatattt catttaaaca atcacaatac
    13921 gaattgccat ttgaacaaat ggattacaaa taaggtggtc catcaatggc atatagtgcg
    13981 atgaaacgtt tgttactgat gataccgttg ttgattgtca ttagcttttt gacttttgca
    14041 ttaacgcatt tatctagtga agatccagcc gtcgtcattc tacatgcaca agaagtacca
    14101 gatattacgc aaagtttaat tgaacaaaca cgtgccaagt accatttaga tgcgccgttc
    14161 ctcgtacaat actgggaatg gctgcaatcc gcggtacagc tacaatttgg acatagtttc
    14221 gtaaccggcg aagatgtcgg tttgagactg tggcctgcat tttttaatac attgaagtta
    14281 acattgattt caagtgtggc gattattgtg ttgtcgctgt tgtttggtat tttgacagca
    14341 ttgttgcgtg ggacatggtt tgatcgtatg acacggacga cagctttcgt attaaccgcg
    14401 attccatctt attggctagc ggcgatattg attatttttc tatcagttaa attgaatgca
    14461 ttaccgacgt cgggattaac aggtcctgaa agctatattt tacctgttgc ggtaatcacg
    14521 cttggttata ccggcattta ttttagaaat gtcagaagtg cggtcattca gcaacttgat
    14581 caagattatg tgctctatat gcgagcgatg ggtgtgccga tgtcgcaact gctcgtttat
    14641 gtggcacgta atgcaatgca agtcgtcgtt tctatttttt gtatgtcgat tcctattatt
    14701 ttaggcggtt ctgtcgtcat cgaaaatgta tttgcgtggc cgggtatggg tcaactgagt
    14761 gtcaaagctg tgttggaaca agattttcca atgattcaag catatgttct tatcgtttcg
    14821 gtactattta tcttatttaa tacattggca gacgtcatta atatgtggct gaacccgaaa
    14881 ttaagggagg agcattaaga tgattgtttt ccaaagatta ttaaatgata atggcgcaaa
    14941 atgggcgttg gcaatcattg ctgtttatat tttactcggg atattcgcgc cgattgtaac
    15001 gccttatgac ccgaatacag tgaatatcga tgacaaattt gccggcatgt catttgcaca
    15061 ttggcttggt acggaccatt taggtcgaga tattttaaca cgcttgattt ttgcgatacg
    15121 tccgagcttt ttgcttatct tgtttgcgtt agcgtgttcg gtgttgatag ggacgctact
    15181 cggcttcatc tcaggctact ttgggcgctg ggtggatgca ctcgtgatgc gtatttgcga
    15241 tgtgatgtta tcgtttccta catatgttat gacgctcgct ttgatcggtg tactcggcat
    15301 tgggttaaaa agtattatcg ttgcactgat cattacgcgc tgggcatggt tttgccgaat
    15361 tatccgcaca agtgtgatgc aatatcgcaa ttcagatgat gtgaaatttg cacgtacgat
    15421 tggtctgtca cacgctcgga ttattatgac acacattttg ccgcgaactt tagcagatat
    15481 tgcgattatt tcaacgagct cgatggtgtc gatgatctta caaatttcag gattttcatt
    15541 tttaggactc ggcgttaaag caccgacagc agaatggggg atgatgatga atgaagcacg
    15601 taaagtgatg ttcagtcacc ctgagttgat gtttgcgcca ggtattgcga ttatcgtcat
    15661 tgtgttagcg gtgaactttt tatccgatgc gctccaaatt gcgattgatc caaaattgtc
    15721 acaacaacaa atgaagcaac gcattaagaa agggtggata taatggtaga acaattgatg
    15781 cgtgtagaag atttaacact cattgatggt catacgaacc atgtcctcgt ccaccacttt
    15841 aatttgacgt tacatcgtgg tgaggtcatt gcgattatcg gtgaaagtgg cagtggtaaa
    15901 tcgatgacgt gtaaagcatt actgggattg aacgaccgta atattcgaat gagcggtgaa
    15961 atttggttcc aagaagaggc gcttcataat gcgtctgaag cggactttcg aaaaatcaga
    16021 ggccgacgta ttgcaatgat tatgcaacaa ggtgcgacag cgtttaaccc ttcttttaca
    16081 gttggtgcac agttgacgat gatgttgaaa cagcaccgtc ctatgtcgac acaacaacag
    16141 aaggcgacgt tacaacatta cttcgacatg cttggtttac gagattttga gcgtatttta
    16201 aaatcatatc cgcatcaatt gtcaggaggc atgttgcaac ggttaatgat tatattagca
    16261 ctcgcactcc aaccggacat cattattgcg gatgagccga ctacagcact cgatgccatt
    16321 acacagtatg aagtcattga agaattacgt gaggtcaaag aaaaaatcgg ttgtgccatg
    16381 atttttgtct ctcatgactt agcagttgta aagtcgattg cagatcaggt tattgtgatg
    16441 cgtaatggtg atgtcgttga agcaggacca gcacatcaat tattcacagc accgcaacat
    16501 gcgtatactc aatttttgat tgcagcacga gatcgtgtga cacgttatta caaatcattg
    16561 cgaggtgatg cgtcatgtta gaagttcaaa acgtcacgaa atcttatcgt agtggtgtga
    16621 agaggcaaaa acgacaaatc gtgaaacaag tcagttttca atgcagtaaa ggacaaagta
    16681 tagcgattat tggagaaagt ggtagtggta aatccacatt ggcgcgtatg atattaggta
    16741 ttgaaaagcc agatacagga actgtgatgt tggatggaca accggtctgt caacgtcata
    16801 cccgtcttgg gaaaatgagc gtcgtgtttc aagattacaa gtcttcactg catccctatt
    16861 tcaatgttcg tcaaatttta aacgaggcac ttagtcaatg cgatacaccg gttgacgata
    16921 aagaagcgca tatgactgct ttgctcgaac gtgtcgggtt aagtgcagcc tttttaaata
    16981 aatatcctca gatgatgtca ggaggagaag cgcaacgtgt cgctattgca agagcggtca
    17041 ttacgaatcc agactacatt gtgttagatg aagcgattag tgcgctcgac atgtcgattc
    17101 agtcgcaaat tctagattta ttaacgacac tgagagataa atatcagctc agtttgattt
    17161 tcattacaca tgatattcaa gcggcggtct atttatgtga agatttgatc atttttaatg
    17221 acggtcaaat tcaagagcga ctcaatagac atcagttgaa aacgcttcaa aatgattata
    17281 cgcgtgaact ttttgaaaaa caatttatga attaggaggc tttgatatga aaggtgcact
    17341 cgcttggcct tttttgagat tgtatattct cgcgctattt ttctttagtg cgaatgctat
    17401 tttaaatgtc atgatcccgt tacgcggaca tgatttaggt gcaaccaatg cgaccattgg
    17461 tattgtcatg ggggcataca tgttgactgc catgcttttt cgtccatggg cagggcaagt
    17521 tatcgccaaa gtcggtccca ttaaaatatt aagatggata ttaattatta atggttttgc
    17581 actgatctta tatggattta caggtttaga aggttacttt attgcacgtg tgatgcaagg
    17641 tgtatgtaca gcctttttct ctatgtcatt acaaatcggg attatcgatg cgttacctga
    17701 agaggatcgt tcacaaggta tttccttata ctcactcttt tcttacatac caggcattat
    17761 cggaccaatg attgcagtgg ggatttggca attggataac ttgagttatt tcgcattgac
    17821 gatgatcatt atcgcgatta cgacaggtgt ggtcggtttc agtgcgacgc ttcatggaca
    17881 tgatgatgca gacacgactc ctgcgcaaca agaaaagatg ccatatggtg cgatgacagt
    17941 gttcttgcag ttatttaaaa atccgttttt attaaaagct gggacgatta tgcttgttgc
    18001 ctcaattgga tttggtgcag tggcaacgtt tatcgtgttg tatgtcaata aatatcaagt
    18061 cggtcacgcg agtttatttt tagctgtaca agccataacg gttgtatttg cacgtttctt
    18121 tttacgtcaa tacattcctt cagatggacg ctggcacgtt cgttttatgt taggtgtcct
    18181 cggattatta actgtcgcgc tgttattcat tgcaatcggt ccttatgtcg gcggatggat
    18241 actttatatc agtgctgtta tgattggttt gacgcaagcg atggtgtatc cgacattaac
    18301 ttcattttta agctttaaat taccgaaagt tggacgaaat atgttactcg gtctctttat
    18361 cgcaacagct gacttaggtg tttcactcgg ggctgcatta atggggccta tagcagatat
    18421 ggttggctat gcaaatatgt atctcatttg tggtatttta atggcattca ttacactgat
    18481 gagtattgag agaagaccgc agtttataga aaaataacgc agaaaatgaa caggctaggg
    18541 tgcatttcaa agtttcctag cctgttttca attgaaaaaa taaattttaa aggtagagaa
    18601 atatcttaat aaaacagtat tagtgacaaa gtcttgagtt tcgaaatata ttttaataac
    18661 agaaaatata cacaagcggt tattaaaatt ttgaaaaatc gctatacaca tcattgtgca
    18721 tcaaatttaa tataatatga caaatcggaa ttcacaatct cttcatctaa tgcgccattc
    18781 cattgatgat ggtaattcaa tggttgctca gaagcttgcc acacttcaaa acttttacgg
    18841 tcatcccata atgaaatcac aacataatga ttttgtgggt cccagggtct caaaacacgt
    18901 agcgatatga agccatgtac atcattcaaa tctgctgtgc gacttagaaa gcgttcctca
    18961 aatgtttcac tttgattcag atctacttta atataattta agacacaaaa atgatgcggt
    19021 gtgagctcgc ctgtcgcttc tatagcagta tatgttttgg tatcattatt tttatatatg
    19081 gtcactgttg tcccatcttc ttcaatttga taaagaaaat ctttatgaga gagtatcatg
    19141 ctttatacct ccttatactt attaacaaat acccgttatt tcacatttta attgcacaaa
    19201 ttaaatttat cgcaaattat atattacatt ttctaaattc aatgtaaaat ttaaaaacga
    19261 atattaaatt aaaaaccgcc acatatcttt atgtagcggt gaatcagcag cataatgaaa
    19321 catatagaga gggcaacata gtattaaaaa atttttaaat gtcacatttt ataaattaaa
    19381 ctttaattcg aatgtgtatt gacctgttct ttttgttcga cagcaatact ccataataaa
    19441 aagacgagtc caattaatgt gagtaatggc gcgattaaac ttagactagc gatggggagt
    19501 gtgctgacaa caagaccgcc gataaaagca cctaatgcat ttccgatatt aaaggcggat
    19561 tgattgagtg tactggaaag tgtcggcgct tcttgggaaa tgagcgtact tttgtattga
    19621 agtgaagggc tcatgctaaa gccaataaaa ccgaaaagaa agacgccgat caccatgatt
    19681 atcgggtgga actgaatgaa gtagagcagt ccaaagtaaa gcacaaaaat aataaaaatg
    19741 ctcattaatg ctttgtttaa attccaatct gcaagcttgc cacctacaat attaccgagt
    19801 gtcacgccaa caccgaatac aatcagaata gatgaaatga attgttcagg aatgtgggtc
    19861 acatcgatga gtacagatga aatataagta aagtaggcga acacactact aaaaccgaac
    19921 aatgtcatcc cgagagttaa ccacagtctt ttttctttta aaatgcgtaa ttcatctttg
    19981 atagaagcgg tacgcatttc ttttggcatc gggacaaaca tcataatgcc gatgagtgca
    20041 atgacgccaa tgacagcaat aattaaaaac gtcatgtgcc aaccgagttt ttgtccaatt
    20101 aatgtaccga atggtacgcc gagaatgttg ctcaggctga gacccataaa cattaatgcc
    20161 attgcacttg cacgatattg gcttgcgacc atacttgcag ctaaaataga gccaatgccg
    20221 aaaaatgagc catgtgcaag tgatgtgacg atacgactga gcatcaatgt cgtgtaattc
    20281 ggactgagac caccgagaat gttaccgaga ataaaaatgc ccatcagcaa cattaacagc
    20341 gctttacggt taagtcggaa agtgagcatg acgatgatag ggcctccaat cgcgacacct
    20401 aaagcgtaac cagtaatcaa ttgtcctgcc tggctcacag acacatttaa atcattcgcc
    20461 acgttaggaa gtaagcccat gatgacgaat tcagtcattc caatcgcaaa tgccccaatc
    20521 gctaacatcc atattgcaat aggatacttc ttcataatgg atacctcctg atttatcttt
    20581 ttaacagagt tatcgtacat atcttatagt tataattcaa tatgtgggtc tttaccagaa
    20641 aatcaaagta agctcttgtt cgtatagttt tgttgatatt tagttacctt atgaactagg
    20701 tttgatttgt atggttggaa gagctgattt cattaaagta cgacggctta gaaaatcaaa
    20761 ttcagtatag agacgatgat aaggagagca accaacactt tttggacgta ctcaggcatt
    20821 tggcgtccta tttttaagcc aagtggcgca aataacatac ttccaacaac taagaataat
    20881 gcatcaccaa gtggaatata cccttgaaaa agtttaaaca taaaggcccc tatagaagaa
    20941 ataaaagcaa tcacaacact atttgccacg acagtatgca tcggtatttt gaaaaaaact
    21001 aataatactg gaataattat aaaggcgcct ccagccccaa tcacaccaga aattgcacca
    21061 atgactaaac ctgtcaatag cagtacaact ttactgaatt ttaagtttgc ttctgtttgt
    21121 ggtttgattt taatcattat taagacgagt gccaatatag caatgacaac atatacgcta
    21181 tttacgaatc tctctgttaa tacttctgca attgtagctc ctaacgcact accgatgagc
    21241 atgctacttc ccatccaaag aatgagttta agagaaaaat ccggtgtttg acgcgcacgt
    21301 attgaactgc ttaaagtact aaaaaatact tgcgcagatg taagtcctga agcgatataa
    21361 gcattgtaag aagggaggcc aagcataggg ggaataatga gtagtgcggg ataaataata
    21421 atcgcaccgc ctatacctac catacccgag agaataccac caataatacc gaggagcgag
    21481 agaaaaatat aaagcattat ttacttttca ccaataagtt cacagcttcg tcaatgattt
    21541 gttgtctatt ttcttcgttt tcttctgctg ccttaataca ctctactaaa ttctcactaa
    21601 taataatact aatgagacgt tgtaacgaac ctttagaagc acttaattgt gtcacaatat
    21661 ccttgcagtg ctgttcttct tccatcattt taatgacgcc atttaattga ccttgaactc
    21721 ttttaattcg gttaatcatt tttttatcgt attccatacc ttatgtcctc ctaaagtaat
    21781 atatgaggtt tatcatataa aaaagcaaga aatttgtcaa atacccccgt aggtatttga
    21841 caagagattc agcatccatt attatacccc tataggtatt tggaggaggt ctaatattga
    21901 attttagtga acttgagata aaaagtttaa agaaagatga acttgagcga ttaggagaac
    21961 tagggcaatt gatagatgtt cgtacggatg aagaatatca agaaggacac atccgagggg
    22021 caaaatcttg gccgttggat caaattgaat tatttaaagg tgataaaaat caaacgtatt
    22081 atctttattg cagaagtgga aagagaagtg cacaagc
//
