LOCUS       NZ_CP015098            22239 bp    DNA     linear   CON 03-MAR-2024
DEFINITION  Streptomyces qaidamensis strain S10 chromosome, complete genome.
ACCESSION   NZ_CP015098
VERSION     NZ_CP015098.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces qaidamensis
  ORGANISM  Streptomyces qaidamensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
REFERENCE   1  (bases 1 to 9083372)
  AUTHORS   Zhang,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-APR-2016) State Key Laboratory of Cryospheric
            Sciences, Chinese Academy of Sciences, Donggang West Road 320,
            Lanzhou, Gansu 730000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 278x
            Sequencing Technology :: Illumina HiSeq 4000; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 10:55:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,226
            CDSs (total)                      :: 8,137
            Genes (coding)                    :: 7,871
            CDSs (with protein)               :: 7,871
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 266
            CDSs (without protein)            :: 266
            Pseudo Genes (ambiguous residues) :: 0 of 266
            Pseudo Genes (frameshifted)       :: 119 of 266
            Pseudo Genes (incomplete)         :: 213 of 266
            Pseudo Genes (internal stop)      :: 25 of 266
            Pseudo Genes (multiple problems)  :: 80 of 266
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:26:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8335493
            Orig. end                         :: 8357732
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP015098.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22239
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="29"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..22239
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22239
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12239](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12239
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            571..1419
                     /locus_tag="A4E84_RS36550"
                     /old_locus_tag="A4E84_36550"
     CDS             571..1419
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (8-230). E-value: 3.7e-34. Score:
                     110.0. Matches aSDomain:
                     nrpspksdomains_A4E84_RS36550_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013006315.1"
                     /locus_tag="A4E84_RS36550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_36550"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_062930653.1"
                     /transl_table=11
                     /translation="MTYKTLALRREGRILHVDFDNAPINLMTIEMVGELFDLAGQLVFD
                     RETSVVVFGSANPEFFLAHFDLNDLFRTMSDPDVPQSKYDDINVVQALTTMWEALPQVT
                     ISLVDGVCRGAGLEFLLATHMRFATLESRLCFPEASGGFLPAGGGTTRLALQIGPARAR
                     EVILSARDFDGEEAAAYGIVNRALPADDICGYVDDLAQRLAARSAGSVAAVNEVFTKVY
                     NRAVDAQFSGFGVENNAMRTLLVIPAVQEYLQKFAALQDAEHELDLPATIAAQGDLTTA
                     K"
     aSDomain        595..1260
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4E84_RS36550_ECH.1"
                     /evalue="3.70E-34"
                     /label="A4E84_RS36550_ECH.1"
                     /locus_tag="A4E84_RS36550"
                     /protein_end="230"
                     /protein_start="8"
                     /score="110.0"
                     /tool="antismash"
                     /translation="RREGRILHVDFDNAPINLMTIEMVGELFDLAGQLVFDRETSVVVF
                     GSANPEFFLAHFDLNDLFRTMSDPDVPQSKYDDINVVQALTTMWEALPQVTISLVDGVC
                     RGAGLEFLLATHMRFATLESRLCFPEASGGFLPAGGGTTRLALQIGPARAREVILSARD
                     FDGEEAAAYGIVNRALPADDICGYVDDLAQRLAARSAGSVAAVNEVFTKVYNRAVDAQF
                     "
     gene            1437..2744
                     /locus_tag="A4E84_RS36555"
                     /old_locus_tag="A4E84_36555"
     CDS             1437..2744
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012656.4"
                     /locus_tag="A4E84_RS36555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_36555"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_062930654.1"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.9e-27, bitscore:
                     95.2, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQQTEENVSAAVRPGLPHVELTGFEPPLGDDERAVQQAMHQFAR
                     EVMRPAGIAIDRLSAEEVVAPDSPYWQFLKTAAASGIEFDATVDGVPPQALARLQAIVV
                     EELGWGDAGLAVSLGAGAFPRLMAARSGNQELVDLCEGRLGCWIGTQPDRGSDGLSLYP
                     AERHAAARQGNKGNLTARVSGGEIVISGQSSAWVSNGPVAQVGLLTIAADYGEGFFDAE
                     GHPRGVEVVVPLDLPGVSRGRPLEKLGKRALPQGEVYFDDVKVPARFALSLGDDYWPGH
                     ASTWSSAGVAMGQIMTGLARAAFEYALEYCHERRQGGALLADHQLVQYRLGAIARKLET
                     MRAVSRRATDYTFLSPKKHPYYTAGSKVTCTDLAFEVADEALQLFGGYGLTREYPMEKL
                     FRDARAARIEDGENHLLTMKFGYLTALLHRAGWARP"
     gene            2773..4344
                     /locus_tag="A4E84_RS36560"
                     /old_locus_tag="A4E84_36560"
     CDS             2773..4344
                     /NRPS_PKS="Domain: AMP-binding (7-421). E-value: 6.4e-98.
                     Score: 319.9. Matches aSDomain:
                     nrpspksdomains_A4E84_RS36560_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="A4E84_RS36560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_36560"
                     /product="AMP-binding protein"
                     /protein_id="WP_062930655.1"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-105, bitscore:
                     352.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVTDFFDRGWRANPDGVAFIAGERSFTYQEIGELSCRVAHALLE
                     RATGREAKGAVLAGNDPVAWACVLGLWRAGLAWVPVNPASPPEEIQRLLKGFDCEVLFC
                     HEPFLPVVEKLRPDLDELHTVVSLGSDAVIASSAGAVTFEEFLRDAAADRPDFTPSPAS
                     VAGIMPTGGTTGAPKGVMNTHRGLSVSAVQQMLAASYREDDPVVNLVAAPMTHTAGTLT
                     LPCTARGGTVVVMSRPDPVQLLDLVEKHRVTELFLPPTVIYRLLEIPGIEQRDFSSLKY
                     LMYGSAPMSTEKLRRAIEVFGPVLFQGYGQTEAPAAIAFLRPEEHFTDGRIADDSRLSA
                     AGRPAPLVRVEILDDDGRILPAGETGEICVRGDLVMKGYYKAPDKTAEALVDGWLHTGD
                     VGFLDAEGYLHITDRKKDMIISGGFNVYPSEVEQVVWSHPAVQDCAVIGVPHEEWGEAV
                     TAVVELNPGAQLTEEALIAYCRPQLGGIKTPKQVVFLDVLPRSANGKVLKKDVREPFWR
                     GHERQI"
     aSDomain        2794..4035
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4E84_RS36560_AMP-binding.1"
                     /evalue="6.40E-98"
                     /label="A4E84_RS36560_AMP-binding.1"
                     /locus_tag="A4E84_RS36560"
                     /protein_end="421"
                     /protein_start="7"
                     /score="319.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DRGWRANPDGVAFIAGERSFTYQEIGELSCRVAHALLERATGREA
                     KGAVLAGNDPVAWACVLGLWRAGLAWVPVNPASPPEEIQRLLKGFDCEVLFCHEPFLPV
                     VEKLRPDLDELHTVVSLGSDAVIASSAGAVTFEEFLRDAAADRPDFTPSPASVAGIMPT
                     GGTTGAPKGVMNTHRGLSVSAVQQMLAASYREDDPVVNLVAAPMTHTAGTLTLPCTARG
                     GTVVVMSRPDPVQLLDLVEKHRVTELFLPPTVIYRLLEIPGIEQRDFSSLKYLMYGSAP
                     MSTEKLRRAIEVFGPVLFQGYGQTEAPAAIAFLRPEEHFTDGRIADDSRLSAAGRPAPL
                     VRVEILDDDGRILPAGETGEICVRGDLVMKGYYKAPDKTAEALVDGWLHTGDVGFLDAE
                     GYLHITDRKKDMIIS"
     CDS_motif       3271..3324
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4E84_RS36560_0001"
                     /evalue="1.60E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="A4E84_RS36560"
                     /protein_end="184"
                     /protein_start="166"
                     /score="17.6"
                     /tool="antismash"
                     /translation="IMPTGGTTGAPKGVMNTH"
     CDS_motif       3853..3939
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4E84_RS36560_0002"
                     /evalue="1.80E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="A4E84_RS36560"
                     /protein_end="389"
                     /protein_start="360"
                     /score="29.9"
                     /tool="antismash"
                     /translation="PAGETGEICVRGDLVMKGYYKAPDKTAEA"
     CDS_motif       4012..4068
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4E84_RS36560_0003"
                     /evalue="2.20E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="A4E84_RS36560"
                     /protein_end="432"
                     /protein_start="413"
                     /score="10.9"
                     /tool="antismash"
                     /translation="RKKDMIISGGFNVYPSEVE"
     gene            4704..5735
                     /locus_tag="A4E84_RS36570"
                     /old_locus_tag="A4E84_36570"
     CDS             4704..5735
                     /NRPS_PKS="Domain: PKS_ER (136-253). E-value: 4.7e-16.
                     Score: 50.7. Matches aSDomain:
                     nrpspksdomains_A4E84_RS36570_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013006320.1"
                     /locus_tag="A4E84_RS36570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_36570"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_062930657.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.7e-23, bitscore:
                     81.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPSTVNRQWLLERRPVGAVAAEDFRFNEADIPVPTDGEVLVRSL
                     YFGYDASQRIWLTDDGGYMEPIRIGEPMRTMGIGQVVASRDPGYQVGDLVEGFLSWQDY
                     VLARGDGPMPLRVLPPADHPLSWHLGVFGVGGLTAYFGITDGLQVKPGDTVVVSAATGA
                     TGSLAVQIAKALGAKRVIGTAGGEEKCRWVVEKTGCDVAIDYKTDNLDARLRELCPDGV
                     DAYFDNVGGDMLDTMLLHMNPLGRVLICGAMSSGYCDVKMQGPSNYMRICTYQLTVRGI
                     LLFFYRDRLAEGAAQLGEWVREGRLHVEEHVVEGFEHAPALLPTMFTGKQPGKLILKVA
                     DPD"
     aSDomain        5112..5462
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4E84_RS36570_PKS_ER.1"
                     /evalue="4.70E-16"
                     /label="A4E84_RS36570_PKS_ER.1"
                     /locus_tag="A4E84_RS36570"
                     /protein_end="253"
                     /protein_start="136"
                     /score="50.7"
                     /tool="antismash"
                     /translation="LTAYFGITDGLQVKPGDTVVVSAATGATGSLAVQIAKALGAKRVI
                     GTAGGEEKCRWVVEKTGCDVAIDYKTDNLDARLRELCPDGVDAYFDNVGGDMLDTMLLH
                     MNPLGRVLICGAM"
     CDS_motif       5157..5219
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4E84_RS36570_0001"
                     /evalue="6.70E-04"
                     /label="PKSI-ER_m5"
                     /locus_tag="A4E84_RS36570"
                     /protein_end="172"
                     /protein_start="151"
                     /score="12.4"
                     /tool="antismash"
                     /translation="GDTVVVSAATGATGSLAVQIA"
     gene            6047..7060
                     /locus_tag="A4E84_RS36575"
                     /old_locus_tag="A4E84_36575"
     CDS             6047..7060
                     /NRPS_PKS="Domain: PKS_ER (14-254). E-value: 1.7e-28.
                     Score: 91.6. Matches aSDomain:
                     nrpspksdomains_A4E84_RS36575_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019763220.1"
                     /locus_tag="A4E84_RS36575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_36575"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_062930658.1"
                     /sec_met_domain="ADH_N (E-value: 3.3e-15, bitscore: 54.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.1e-18, bitscore:
                     64.9, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLMRAARLHLPTHTLTIEEVPRPTPGPGHVLIEVAAAGVCMSDV
                     HLIDGTLGRPPHLQGDTVTVGHEVSGTIVELGDGVTQFTLGQRVVLQAGDIRGGQMHTR
                     GVDFDGGWAEYALASVESVFPLPDSLPFEQAAIIPDAVSTPWDAIVRTAAVRPGEAAGV
                     WGVGGLGAHAVQLLRAVGAFPIIAVDPLAAARGRALDLGADLALDSGDPTFREQVLSVT
                     KGRALNAAFDFAGVTPVHEQALSVLAPEGRLILAGLSGRPLVVNDSTMFSYLKHEIRGH
                     FGTKLDAVPQLVDLVGGGRLDFSRSITDVLPLEKASVAVERLHTKEGNPLRLILKP"
     aSDomain        6089..6808
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4E84_RS36575_PKS_ER.1"
                     /evalue="1.70E-28"
                     /label="A4E84_RS36575_PKS_ER.1"
                     /locus_tag="A4E84_RS36575"
                     /protein_end="254"
                     /protein_start="14"
                     /score="91.6"
                     /tool="antismash"
                     /translation="TLTIEEVPRPTPGPGHVLIEVAAAGVCMSDVHLIDGTLGRPPHLQ
                     GDTVTVGHEVSGTIVELGDGVTQFTLGQRVVLQAGDIRGGQMHTRGVDFDGGWAEYALA
                     SVESVFPLPDSLPFEQAAIIPDAVSTPWDAIVRTAAVRPGEAAGVWGVGGLGAHAVQLL
                     RAVGAFPIIAVDPLAAARGRALDLGADLALDSGDPTFREQVLSVTKGRALNAAFDFAGV
                     TPVHEQALSVLAPEGRLI"
     misc_feature    complement(7119..7134)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            <7342..>7543
                     /locus_tag="A4E84_RS43985"
                     /pseudo=""
     CDS             7342..>7543
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014358297.1"
                     /locus_tag="A4E84_RS43985"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="IS256 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MFATVRLRTKVTKGAGSAAARLPWSSSSSSPPRRAGGRQRTPPRG
                     PRPRRSPLRTRPARGAA"
     gene            complement(7553..8011)
                     /locus_tag="A4E84_RS36580"
                     /old_locus_tag="A4E84_36580"
     CDS             complement(7553..8011)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018547842.1"
                     /locus_tag="A4E84_RS36580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_36580"
                     /product="hypothetical protein"
                     /protein_id="WP_062930659.1"
                     /transl_table=11
                     /translation="MPDVWIGLDANARRRNWWWTGFLTLICAGTAEATALSAPATERWW
                     WVAGVGVFWLIALFYMVNRGYGRTLLTPNGMKFRTFVSRRSIRWDEITRIEKRRHQARS
                     GEWWDLCAVRVHGRSLTIPGAFASSQWDADLEEQLVVIREYWSRTVDG"
     gene            8277..9740
                     /locus_tag="A4E84_RS36585"
                     /old_locus_tag="A4E84_36585"
     CDS             8277..9740
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012946.4"
                     /locus_tag="A4E84_RS36585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_36585"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_079129263.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 7.7e-15, bitscore:
                     53.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRACVVGAGPGGIVAAKVLLENGFDVTVFDKYQQVGGIWSSEGCY
                     DGLANQSALHIFEFADLPNRLHFASAVDTQRYLEKYAETFGVLDRVRPGTEVISIRPVE
                     GPGRVGASGWSVDSRPTGDKAADVHRETFDYVVVASGAHHHAQMPELPGRESFRRTVLH
                     SNEVRAGTFAGRRVVVVGGGKSALDLITRAAHEAASATIVQRKVNWMIPERFLLGLVNY
                     KWILFTRLGEALLPRYHDPACVRPIDRIDERVKRALWWLITRDVLLSTGLYRLPRQLRP
                     AHALPFHLAHAGVMPRGYVRAVRRGLIAPKVSAVEAYTDKGLRLATGEEVAADVIVFAT
                     GHHKVFPFLDSSVRVHDDDGRLRLYRGIVPPGADRLGFVGFRQVFNNIMGMELTAHWLT
                     SHFRATLRTTPDEQGMREAIDARLAWQEQVLPGSGGYDFGPYDIHCADELLHDMGLPSR
                     RADNLLAEYLLPGGVAHRYAGLTRSSSAK"
     gene            10001..11077
                     /locus_tag="A4E84_RS36590"
                     /old_locus_tag="A4E84_36590"
     CDS             10001..11077
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003959585.1"
                     /locus_tag="A4E84_RS36590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_36590"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_062930661.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.4e-42, bitscore:
                     143.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSGVVDAQAIDLCAVQRQVDAVLESFLAEKVRAAAGRGHPPEVV
                     ETVRDFLAAGGKRIRALLCVVGWHASGGHGDVTSAVRVAASLELFVAFALIHDDIMDDS
                     ASRRGRPAVHRVMRARLGGGERAERLGAGGALLVGNLALMWAQELLHTAPIESGRQRLV
                     HGLYDAMLEEVMYGQYLDVMGTGRGADDVEAALRIIRYKTATATIERPLQLGAAVAGAD
                     DATMEVFTGLGLPLGEAFQLRDDLLDVFGSPDGACAPGLSDLREGKRTVLLALGLQNAD
                     LVQRARLDRLVGRADLEERDAAEIRDILFATGAREETERMITSRYEHVLRVLDGAGFPP
                     SADRALRGLAVKATQYTS"
     misc_feature    10586..10588
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11169..12239
                     /locus_tag="A4E84_RS36595"
                     /old_locus_tag="A4E84_36595"
     CDS             11169..12239
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019981071.1"
                     /locus_tag="A4E84_RS36595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_36595"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_062930662.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.3e-40, bitscore:
                     138.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEQVLDRVSGYERWFNTLFEEYFDTLSVGLGAPSFSRFTPECLR
                     LLRELSLRGGKRMRVVLLHEAARLVTEEPVEGLEAAALSVELLQTHGLVHDDLIDDSPT
                     RRGGPSTYYAYRERFPARPQAALGLTVLAGDLALALSLRVLLEAKVPVAVRQAMIEVQT
                     RAAADTFVGQIVDLERDFAAAPGEEVLHCVADYKSARYSVLAPLQLGLLAAGEQPALFE
                     KELREYARLVGICGQMRDDYLDLFGDASVMGKPTGTDIRDGKHSYTVSVLLAAVDDAER
                     RVVEAALGDPSCLTETIAAVREIGERRGVPGRMQADMRRCAEQATEVAAGWRSRWREEA
                     VTFFEHLPLWSVNRTR"
     gene            complement(12257..13537)
                     /locus_tag="A4E84_RS36600"
                     /old_locus_tag="A4E84_36600"
     CDS             complement(12257..13537)
                     /GO_function="GO:0004144 - diacylglycerol O-acyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0045017 - glycerolipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014998.4"
                     /locus_tag="A4E84_RS36600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_36600"
                     /product="wax ester/triacylglycerol synthase
                     domain-containing protein"
                     /protein_id="WP_159029661.1"
                     /transl_table=11
                     /translation="MNPFLAPSPADLVLVKAEELAEHPDANARIGAVLHLTGAVPDLAG
                     LREYVTAHLDGLPCLTHVLTGNGPTARWMPADPDMTRHVRAQHAGGDPEALETAVCHAL
                     REPWPEEAPAWRMILLHGHVPDGFALLYLSHHAVQDGANIVAVLDALFGPRALPHQLPA
                     PARDASRPPRAGLRQTARSTVSLLRHARQHRLWQSASHPLSSRRHLLWAQAPSAGLRAA
                     ARDGGASINDVYLTAVVHAITQWAKDAWPRATGTTIPVMVPVNVRTPDEVAVPGNRLFL
                     SRIDLPGGTMPVERRLARTRAVTSVLKSAGHKTVLRAALTRLPRRLLQLLVDASTVPGR
                     LTICASYLVVRQPLHYGEAAVHRIDPIMCCPPGVPLAVVAATYEETTSVSFRIDTALPG
                     ADSLPERWRQAVTELTRSAPPPQGSTP"
     gene            complement(13543..14124)
                     /locus_tag="A4E84_RS36605"
                     /old_locus_tag="A4E84_36605"
     CDS             complement(13543..14124)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003959587.1"
                     /locus_tag="A4E84_RS36605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_36605"
                     /product="hypothetical protein"
                     /protein_id="WP_237305058.1"
                     /transl_table=11
                     /translation="MPRTEARWAWLLSDGGEPRNWMLLLAPLLGWHADGWAGIGWGVIA
                     AVFTAVLPTLILRFGEHRQYWGDRHVRRRQDRIVAAPGVMASVIIGTALLYGLDAPVEV
                     TALVAAMVAVLLALLVITFFWKVSVHSAVASGALAILATVFGPWLLVLAPVVVLIGWSR
                     IRLRCHTAGQVSVGFLIGAAVSSPVFDLVR"
     gene            complement(14297..15079)
                     /locus_tag="A4E84_RS36610"
                     /old_locus_tag="A4E84_36610"
     CDS             complement(14297..15079)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4E84_RS36610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4E84_36610"
                     /product="ABC transporter permease"
                     /protein_id="WP_159029662.1"
                     /transl_table=11
                     /translation="MRFALIEQARNRLALLIVVLFVPLWTTLAFTVVESAPLRFRIRPV
                     GRTVVMDGNILLQINGALQALSLVIAFMMFVATVRSAPFDQRLVRAGFPRSGLALAKCS
                     ALLLVSAVVAAYTTAWMHLFWRPEQPLVLAAGMFTGALVYGGIGMVLAAVVRSELAGMF
                     LAIMISSIDLVLQNPLINPDADSLVVRLLPAYAAVQTSVAAAGLRVVPASCLLLGGGWA
                     VGIAALGITVFAARTRTRLPRAGARAASTGVEHAAPVS"
     gene            complement(15109..15750)
                     /locus_tag="A4E84_RS36615"
                     /old_locus_tag="A4E84_36615"
     CDS             complement(15109..15750)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569178.1"
                     /locus_tag="A4E84_RS36615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_36615"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_062931771.1"
                     /transl_table=11
                     /translation="MSSLDPVLRVRGVRKGYRQRPVLRGVSLDLSAGQLVGVVGENGAG
                     KSTLLRILAGDLVADGGVVERAGLLGCCPQDTVLHQAFTVEQHLQFFQAAYGISSLTRS
                     LELLERLNFSDYRHERVGALSGGTRQKLNLVLALMHDPQVLLLDEPYQGFDWETYLRFW
                     DLAADLRDRGCAVLVVSHLAYDASRLDTLYRLEAGVLQETEQTEPGRAAV"
     misc_feature    complement(15436..15438)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16252..16389)
                     /locus_tag="A4E84_RS43145"
     CDS             complement(16252..16389)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4E84_RS43145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_159029663.1"
                     /transl_table=11
                     /translation="MHWPLYGPAGVPLEVVLGDVKALATLVLHHAAPEEPPLAGVPGSP
                     "
     gene            <16850..17013
                     /locus_tag="A4E84_RS44995"
                     /pseudo=""
     CDS             <16850..17013
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019068410.1"
                     /locus_tag="A4E84_RS44995"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="pirin family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MFWNWSGGRRRRSNRRGGAGWQGRGSAR"
     gene            17266..18132
                     /locus_tag="A4E84_RS36620"
                     /old_locus_tag="A4E84_36620"
     CDS             17266..18132
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018559476.1"
                     /locus_tag="A4E84_RS36620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_36620"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_062930666.1"
                     /transl_table=11
                     /translation="MTIVLGTPTVDGVREAMAALREWQYDEAPMQLHSGDIGWNYRFGT
                     AETAAAVRTWSRDGRILAVGMLDSPSLVRMTVAPDTFQDEDLARRLVEDLSLPERGVLR
                     EGAVCIEAPLGLLLHDLLSKEGWGVDEPWTPLFRDLTEPVEDPGVRIESIGPEQAQDFA
                     DVLRSAFNTSRPTREYWHAMSAGPFYADARCLGAYDDRGSVAAVVTVWSAGPGKPGLVE
                     PMGVHENHRGRGYGRAITVAGAAALREMGSSSVRVCTPSSNVGGVATYKAAGFEVRPEV
                     RDRIRTA"
     gene            complement(18564..19151)
                     /locus_tag="A4E84_RS36625"
                     /old_locus_tag="A4E84_36625"
     CDS             complement(18564..19151)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="A4E84_RS36625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_36625"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_063827595.1"
                     /transl_table=11
                     /translation="MPVPTRTRILDAAWDLFLRQGFTGTTVTQIEAAAALSAGSGSFYR
                     HFRSKKEVLQAVVDREVDRADTERQTGPEPEETGGDVRIALALEFERRLANLRRLHPLM
                     ELVARERDHLGASVDHLGELLVARNVSIRSQRLAGWMAAGAIPTRDAEALAAVITFALT
                     GYHLSVRFFGHQPTGVSEEALITTLVDLVAGV"
     misc_feature    complement(19210..19222)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 22.66"
                     /tool="antismash"
     gene            19268..20449
                     /locus_tag="A4E84_RS36630"
                     /old_locus_tag="A4E84_36630"
     CDS             19268..20449
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4E84_RS36630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4E84_36630"
                     /product="PD40 domain-containing protein"
                     /protein_id="WP_159029664.1"
                     /transl_table=11
                     /translation="MRIRHLTTLAGSFVLACLPVQVHALPVKAADTSTSSVVATSQRSG
                     LNFDPDKGTLDGSPVDHLPDHIRLLDIQLPNGGAPQRADWSPDGKRLAFLDAPIGDLWE
                     YDLATGASRNLTTTSALHGGVLRAHHLTNGDIVMCAVAERSADDPEGDRFRGELWVLQR
                     PLGTRAPVRLGESCWEGVAVSKQSGSTRIAWNQSTIDFTKMPDVITEALVGKSKILTGR
                     IVYRNGRPEITDRTVALDKRDVSLVTPAVEAQDFRSLPDGDADPDDELIFSAYFHKGGQ
                     VMGVNLDTGAIKDYAPTSLLFDEAEGTDPAGRYTMVERDFAIALSPGMVDIWRLSLDGS
                     GTFERMTTFNHYKGFGANNPVVSPDGTQMAFGLKVEGGAEGEGDGILLMDLSR"
     misc_feature    19283..19285
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(20439..21644)
                     /locus_tag="A4E84_RS45000"
     CDS             complement(20439..21644)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4E84_RS45000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_237305059.1"
                     /transl_table=11
                     /translation="MSTTSMVCRPPKLPKLRPGRPRPPGHPLRSVDTLDSEALAALAPD
                     VVLTQDLCEVRAVSYSGVSEAVRVLDGGGPKVLSRSPAPWMTCSTVWCGWGACWVFGAS
                     PNSAARLRNRLAAVRRLTAGRRRARGVAIEWLDPLWPAGHRVPEQLACAGAEPLLAAPG
                     EHTKPMERAAVRAARPDVVLVLPCGFSPERTLSERELLTSLPGWDELPAGRAGEVWVLD
                     GPARFNRPGPRVVRGAEVLAQVLHGVAAGEPVGETEARRRRPRPARERVRMRSCLRGPL
                     PGCGPAAGQVVAGEQCHLGQAGAGMLGDVRLDAVDVGRQGGSEDVPWCAVGDHASGPHR
                     AEAVAGRGGEVEVAQRDHGGDSEAADETERVELVAQVEVSDIASRWASTDTLSRRQRLL
                     IY"
ORIGIN
        1 tcaccgacgg cgccgccgcg gcgatcgtct gcaacgaggc gggccgggca cgcctcgggg
       61 gaagccggca cgtccgcgta ctgtcctcgg tcctcggcac cggaaccgtg cgctccatgg
      121 ccgactggga gcactcggtc agcaggctcg cggcgcagga cgcgtacgag caggcaggga
      181 tcgggccgca ggacgtgtcc gtcgccgagg tgcacgacgc gtcggcgttc ggcgagctcc
      241 tccagacgga gctgctggga ttctgcgaga tcgggaccgg aggcgcgttc gccgcgtccg
      301 gcgccaccac cctgggcgga ctcctccccg tcaacccgtc gggcgggctg gagtccaagg
      361 ggcatcccat gggcgcctcc ggcctggcgc agatccacga actggtgcag cagctccgcg
      421 gtgagagcgg agcccgccag gtccccggcg cgcgcatcgc gctggcggag aacgggggcg
      481 gcatgtatgg cggcgaggaa gccgtagccg cgatcaccgt cctcggcgcg taaccgccaa
      541 ctgttgagac atccccgaac ggagcccgcc atgacctaca agaccctcgc tctgcggcgc
      601 gaaggccgca tcctccacgt cgacttcgac aacgcaccga tcaacctgat gacgatcgag
      661 atggtcggcg aactgttcga cctggccgga cagctcgtgt tcgaccgcga gacctcggtc
      721 gtggtcttcg gcagcgccaa cccggagttc ttcctcgcgc acttcgacct gaacgacctg
      781 ttccggacga tgagcgaccc cgacgtgccg cagagcaagt acgacgacat caacgtcgtc
      841 caggcactca ccaccatgtg ggaagcgctg ccgcaggtga ccatcagcct ggtcgacggc
      901 gtctgccgcg gcgccggact ggagttcctc ctcgccaccc acatgcgctt cgccactctg
      961 gagagccgcc tgtgcttccc cgaggcatcc ggcggattcc tcccggccgg cggaggcacc
     1021 acccgcctgg ccctgcagat cggtccggcc cgtgcccgcg aagtcatcct gtccgcccgt
     1081 gacttcgacg gcgaggaggc ggccgcctac ggcatcgtca accgcgctct gcccgcagac
     1141 gacatctgcg gctacgtcga cgacctcgcg cagcggctcg cggcccgctc cgccggctcc
     1201 gtcgcggcgg tgaacgaggt gttcaccaag gtctacaaca gagcggtcga cgcccagttc
     1261 tccggcttcg gtgtggagaa caacgcgatg cggacgctgc tcgtgattcc cgccgtccag
     1321 gagtacctgc agaagttcgc cgctcttcag gacgccgagc acgagctgga cctgcccgcc
     1381 accatcgcgg cgcagggcga cctcaccacg gccaagtgac ggagagggag ctgaccatgc
     1441 cacagcagac cgaagagaac gtctccgccg cggtgcgccc cggcctgccg cacgtggagc
     1501 tgaccggctt cgagccgccg ctcggcgacg acgagcgcgc ggtccagcag gcgatgcacc
     1561 agttcgcccg cgaggtgatg cgtccggcgg gtatcgcgat cgaccggctg agcgcggagg
     1621 aggtcgtcgc cccggactcc ccgtactggc agttcctgaa gacggcggct gcctccggca
     1681 tcgagttcga cgcgacggtc gacggggtgc ctccccaggc cctggcccgc ctgcaggcca
     1741 ttgtcgtcga ggaactcggc tggggcgacg ccggcctggc cgtctccctg ggggccggag
     1801 cgttccccag gctgatggcg gcgcggtcgg gcaaccagga gctggtcgac ctgtgcgagg
     1861 gcaggctcgg ctgctggatc ggcacgcagc ccgaccgcgg ctccgacggc ctgagcctgt
     1921 acccggcgga gcggcacgcc gccgcccgcc agggcaacaa gggcaacctg accgcgaggg
     1981 tgtccggcgg cgagatcgtg atcagcgggc agagctcggc ctgggtgtcc aacggaccgg
     2041 tcgcccaggt cggcctcctg acgatcgccg ccgactacgg cgaggggttc ttcgacgcgg
     2101 agggccaccc gcgcggtgtg gaggtcgtcg tgccgctcga cctgccgggg gtcagccggg
     2161 gcaggccgct ggagaagctg ggcaagcgag ccctgccgca gggcgaggtc tacttcgacg
     2221 acgtgaaggt gcccgcccgc ttcgccctgt cgctcggcga cgactactgg cccggtcacg
     2281 cgtcgacctg gtcctcggcc ggcgtcgcca tgggccagat catgacgggg ctggcccggg
     2341 cggccttcga gtacgcgctg gagtactgcc acgagcggcg gcagggcggc gcgctgctcg
     2401 ccgaccacca gctggtgcag taccggctgg gcgccatcgc ccgcaagctg gagaccatgc
     2461 gcgccgtctc ccggcgggcc accgactaca ccttcctgtc gccgaagaag cacccctact
     2521 acacggccgg atccaaggtg acctgcaccg atctcgcctt cgaggtggcc gacgaggcgc
     2581 tgcagctgtt cggcggttac ggactcacgc gcgagtaccc gatggagaag ctcttccgcg
     2641 acgcccgggc agcccgcata gaggacggcg agaaccacct gctgaccatg aagttcggct
     2701 acctcaccgc gctgctgcac cgcgccggct gggccaggcc atgagccgcg gacgatcgaa
     2761 aggaaacacc ccatggcagt gaccgacttc ttcgatcgcg gctggcgagc caacccggac
     2821 ggcgtggcgt tcatcgcagg cgagaggtcc ttcacgtacc aggagatcgg ggagctctcg
     2881 tgtcgcgtgg cccatgccct gctggagcgg gcgaccggcc gtgaggcgaa gggcgcggtg
     2941 ctcgccggga acgacccggt cgcgtgggcc tgtgtcctcg gactgtggcg ggccgggctg
     3001 gcgtgggttc ccgtcaaccc cgccagcccg cccgaggaga tacagcggct gctcaaggga
     3061 ttcgactgcg aggtgctgtt ctgccacgag ccgttcctgc cggtcgtcga gaagctgcgc
     3121 cccgacctgg acgagctgca caccgtcgtc tcgctgggtt ccgacgcggt catcgcgtcc
     3181 agcgccggcg ccgtcacctt cgaggaattc ctccgcgacg ccgctgccga ccgccccgac
     3241 ttcaccccct ccccggcgtc ggtcgccggc atcatgccga ccggcggcac gaccggcgcc
     3301 cccaagggag tgatgaacac gcaccggggt ctgagcgtca gcgccgtgca gcagatgctc
     3361 gccgcctcct accgggagga cgaccccgtc gtgaacctcg tcgccgcacc gatgacgcac
     3421 acggcgggca ccctcacgtt gccctgcacg gcgcgcggcg gcacggtcgt cgtgatgagc
     3481 cggccggatc cggtgcagct gctcgacctg gtggagaagc accgcgtcac cgagcttttc
     3541 ctgcccccga ccgtgatcta ccggctgctg gagatccccg gcatcgagca gcgggacttc
     3601 tcctcactga agtacctcat gtacggttcc gcgcccatgt cgacggagaa actgcgccgg
     3661 gccatcgagg tcttcggccc tgtcctgttc cagggctacg ggcagacgga ggcaccggcc
     3721 gcgatcgcct tcctgcggcc cgaggagcac ttcaccgacg gcaggatcgc cgacgactcc
     3781 cggctgtcgg cggcaggccg ccccgctccg ctggtgcgcg tggagatcct cgacgacgac
     3841 ggcaggatcc ttcccgccgg cgagacgggt gagatctgcg tgcgcggcga cctggtcatg
     3901 aagggctact acaaagcccc cgacaagacc gcggaggccc tcgtcgacgg gtggctgcac
     3961 accggagacg tcggattcct cgacgccgag ggctacctcc acatcaccga ccgcaagaag
     4021 gacatgatca tctcgggtgg cttcaacgtc tacccgagcg aggtcgagca ggtcgtctgg
     4081 agccatccgg ccgtgcagga ctgcgccgtc atcggcgttc cgcacgagga atggggtgag
     4141 gccgtcaccg ccgtggtcga gctcaacccc ggtgcccagc tgacagagga ggcgctgatc
     4201 gcgtactgcc ggccgcagct cggcggcatc aagaccccca agcaggtcgt cttcctggac
     4261 gtcctgccgc gcagcgccaa tggaaaggtc ctgaagaagg acgtccgtga gccgttctgg
     4321 cgcggccacg agcggcagat ctagcgaacg gtcagagggt ccccgaggag tacggcgggt
     4381 cggctgcctg cgtgacggcg gctgccgagg aactcgcctg cgtcggccca ggcgtcgtgg
     4441 cctgtccgac tctccacacc gacatgggac ccgtctccgt gccattgccc cgaccgagtc
     4501 ttcggacgtc cccgaccagg gccgcgccga gcttccttct cgccgaggcc ggtacggcgt
     4561 actcgacgca cacctccgtc tgcatggcgg tcacggctac ctgaccggac aagccccggg
     4621 tccgacgaga tcgcgcaaag cgatcggtaa cgacctgggc cggagccacc ccctgtgccc
     4681 gcgactctct caaggagaac ctcatgcccc cttccaccgt caaccgccaa tggctgctgg
     4741 aacgccgccc ggtcggtgct gtcgccgccg aggacttccg gttcaacgaa gccgacatcc
     4801 ccgtgcccac cgacggcgaa gtgcttgttc gctccctgta cttcggctac gacgccagcc
     4861 agcgaatctg gctgaccgac gacggcggct acatggagcc gatccggatc ggtgagccga
     4921 tgcggaccat gggaatcggc caggtcgtcg cctcacgaga ccccggttat caggtgggag
     4981 acctggtcga gggcttcctg agctggcagg actatgtgct cgcccgcggc gacggcccca
     5041 tgcctctgcg cgtgctgccg cctgcggacc acccactgtc ctggcacctc ggcgtgttcg
     5101 gcgtcggcgg actgaccgcc tacttcggca tcaccgacgg ccttcaggtg aagccgggcg
     5161 acaccgtggt cgtgtcggcc gcgaccgggg ccaccgggtc gctggccgtt cagatcgcca
     5221 aggcgctcgg tgccaagagg gtgatcggta cagccggtgg agaggagaag tgccgctggg
     5281 tggtcgagaa gaccggttgc gacgtggcca tcgactacaa gaccgacaac ctcgacgcac
     5341 gactgcgcga gctgtgcccg gacggcgtcg acgcctactt cgacaatgtc ggcggcgaca
     5401 tgctggacac gatgctgctg cacatgaacc cgctcggacg agtgctgatc tgcggtgcca
     5461 tgtcatcggg ctactgcgat gtcaagatgc agggccccag caactacatg cgcatctgca
     5521 cctaccaact caccgtgcgg ggcatcctgc tgttcttcta ccgtgaccga ctcgcggagg
     5581 gagcggccca gctcggagag tgggtgaggg aaggccgcct gcacgtcgag gagcacgttg
     5641 tcgaaggctt cgagcacgcc ccggccctgc tgccgacgat gttcaccggc aagcagcccg
     5701 gcaaactgat cctcaaggtg gcggacccgg actgagtggc acgacaggac caagcgaccg
     5761 gtgacggtgg tcaccggcgc ggagggcggc atgggccgaa gccgcccgcc gcctgagcag
     5821 tacccatcgg ccggcgctgc cgggcatcga cggtgcggca gccgtgatcg cggtgctcga
     5881 ccgtttcggc gccatcgacg gcgcctcgtt ccagctcgcg tgcgggaccg cgcggtcatc
     5941 ggcgccccgc acgacggctg agccacttgc gcaccatccg gctccctccc gtcacccgtc
     6001 gtccgatcgg accggcgagg aaacccttca gaggaaagac acatccatga ccctcatgcg
     6061 agctgcgcgc ctgcacctgc ccacccacac gctgacgatc gaggaggtac cccggccgac
     6121 acccggcccc ggccacgtgc tcatcgaggt tgcggcggcc ggtgtgtgca tgtccgacgt
     6181 ccacctcatc gacggcaccc tcggccgtcc tccgcacctc cagggcgaca ccgtcaccgt
     6241 cggccacgag gtctccggca cgatcgtcga actcggcgac ggcgtcactc agttcaccct
     6301 cggccagcgg gtggttctgc aggcgggtga catcaggggc ggtcagatgc atacccgcgg
     6361 ggtggacttc gacggcggat gggccgaata cgccttggcg agcgtcgagt ccgtgttccc
     6421 cctgcccgac tcccttccgt tcgagcaggc ggcgatcatc cccgacgccg tgtcgacccc
     6481 gtgggacgcc atcgtacgca ccgccgccgt ccggccgggc gaggcggccg gtgtctgggg
     6541 cgtgggcggt ctgggagccc acgccgtgca gttgctgcgg gccgtcggcg ccttcccgat
     6601 catcgcggtc gacccgcttg ccgccgcgcg agggcgggcg ctggacctcg gtgcggacct
     6661 cgccctcgac tccggcgacc ccacgttcag ggaacaggta ctgtccgtca ccaagggacg
     6721 cgctctgaac gcggcgttcg acttcgccgg cgtcaccccc gtgcacgagc aagccttgag
     6781 cgtcctggcg ccagaaggcc gcctgatcct ggccggactg tccggccggc cgctcgtcgt
     6841 gaacgacagc accatgttca gctacctgaa gcacgagatc cgcgggcact tcggcaccaa
     6901 gctcgacgcc gtaccgcagc tcgtggacct cgtgggcggc ggacggctcg acttctcccg
     6961 gtccatcacc gacgtactgc cgctggagaa ggcgagcgtc gctgtagagc gcctgcacac
     7021 gaaggagggc aacccgctac gcctgatcct caagccctga gtcacaccag gccctcactg
     7081 gttccggccc cagcctcata ttggcctgcc cagcatccgt ttacacaggc agttcaccgg
     7141 cggagtgaca tggggcgtcc tccaattctc agcaagccac cgaccgggcc tgacctcgca
     7201 caggcgccat gcgccctctc gtgttccgcg aacgaaacca cggccctccg gccgtggttt
     7261 ctcgtgttcc ggcaccagtg cccccggtca ccgccactcc tggggttccc gtacctcccg
     7321 ttgctgcgac gtgaactccc gaccttcgcg acagtgcgac tgaggaccaa ggtcaccaag
     7381 ggtgccggca gcgcggccgc gcgcttgcca tggtcttcaa gctcgtcgag tccgcccagg
     7441 cgcgctggag ggcgtcaacg caccccacct cgtggccctc gtccgcgccg gagcccgctt
     7501 cgaacgcggc ctgctcgtgg agcggcctga agccaccgcg gcccgagcgc catcagccgt
     7561 cgaccgtgcg ggaccagtac tcgcggatca ccaccaactg ctcctcgagg tcggcatccc
     7621 actggctgct ggcgaaggca cccggaatcg tgagtgaccg tccatgaacc cggacggcgc
     7681 acagatccca ccactcacca ctccgtgctt ggtggcgtcg cttctcaatc cgggtgatct
     7741 cgtcccaccg gatcgatctg cgactgacga acgtgcggaa cttcatcccg ttgggcgtga
     7801 ggagcgtgcg tccgtatcca cggttgacca tgtagaagag cgcgatcagc cagaacacgc
     7861 cgacgccagc aacccaccac catcgttccg tggccggcgc ggacagtgcc gttgcctccg
     7921 ctgtgccggc gcagatgagg gtcaggaagc cggtccacca ccagttccta cgccgggcat
     7981 tggcgtcgag accgatccat acgtcgggca cagccgcgat gctacagact ccagacggca
     8041 cctgtcgccg actgccgcag ggacaaatgg atacggttcc aggtttctga cgcaccgtga
     8101 tgcgcgcgac tgtctccgtc tgtgggcgtt gaccgcgtac gtcgtgcccg ggggtgtggc
     8161 cgtgctcgtt cagcttctga tgcctcaggt accggagggc gccctgggca gggaggcccg
     8221 cgaccgggat gatgagcgag ctggacacgg cgatcgccca tggggagtga cagctgatga
     8281 gagcgtgtgt ggtcggggcc ggccccgggg gaatcgtcgc cgccaaggtg ctgctggaga
     8341 acggcttcga cgtcacggtc ttcgacaagt accagcaggt cggcgggatc tggtcatcag
     8401 agggctgcta tgacgggctg gccaaccagt ccgcgctcca catcttcgag ttcgcggacc
     8461 tgcccaaccg cttgcacttc gccagcgcgg tggacacgca acgctacctg gagaagtacg
     8521 cggagacctt cggtgtgctg gaccgcgtcc ggcccggtac cgaggtgatc tccatccggc
     8581 cggtggaggg gcccgggcgg gtgggcgcct ccggctggtc ggtcgactcc cggcccaccg
     8641 gggacaaggc ggcggacgtt catcgcgaga cattcgacta tgtcgttgtc gccagtggag
     8701 ctcatcatca tgcccaaatg cccgagctgc ccgggcgtga gtcgttccgc aggaccgtgc
     8761 tgcactccaa cgaggtgcgg gccgggacat tcgccggccg gcgcgtggtc gtcgtgggcg
     8821 gcggcaagtc cgcattggac ttgatcaccc gcgccgcaca cgaggcggcc tcagccacga
     8881 tcgtgcagcg caaggtgaac tggatgatcc ccgagcggtt cctgctcggt ctggtcaact
     8941 acaagtggat cctgttcacc cggctcggtg aggcgctcct gccccgctac cacgatccgg
     9001 cctgcgtccg tccgatcgac cgcatcgacg agcgggtcaa gcgggctctg tggtggctca
     9061 tcacccgcga cgtgctgctt tccaccgggc tgtaccggct gccgaggcaa ctgcggcccg
     9121 ctcacgcgct ccccttccat ctggcccacg cgggagtgat gccgcgcggc tacgtgcggg
     9181 ccgtccgccg cggcctgatc gcccccaagg tcagtgccgt cgaggcatat accgacaagg
     9241 ggctccgact ggcgaccggc gaggaagtgg cggcagacgt catcgtgttc gccacagggc
     9301 accacaaagt cttcccgttc ctggactcga gcgtgcgcgt gcacgatgac gacgggcggc
     9361 tgcggctcta ccgaggcatc gtgccacccg gcgccgaccg gctcgggttc gtcggtttcc
     9421 ggcaggtgtt caacaacatc atgggcatgg aactcaccgc gcactggctg accagccatt
     9481 tccgggcgac gctgcgcacc accccggacg agcaggggat gcgggaggcc atcgacgctc
     9541 gcctggcctg gcaggagcag gtactgccag gctccggcgg ctacgacttc ggcccctacg
     9601 acatccactg cgcggacgaa ctcctgcacg acatggggtt gccatcccgc cgcgccgaca
     9661 acctgctggc cgaatacctg cttcccggcg gagtggcaca ccgctacgcg ggcctgactc
     9721 gatcgagttc ggcgaaatga atgcagagca tgagcggccc gacgctcggc gagccgctgc
     9781 cgaggaacgc ccacaagtgt gggtgatcga agtcagggag gtgaccacgc cgagcgtgct
     9841 cttcagcggt gtgggtcgtt ggacggatca tgcagaccaa atgggtgacg cggacagtca
     9901 gcggcctcgg ctgtcgtcag agccctgagt caggggacag ctatcgccca ttgtcgtccg
     9961 tccgcatgaa gctggctccc ctggttggga gtggtgagtg gtgacgtcgg gtgtggtcga
    10021 cgcgcaagcg atcgacctgt gcgcggtgca gcgccaggtt gatgcggtgc ttgaaagctt
    10081 cttggccgag aaggttcgtg cggcggccgg ccgggggcat ccgccggagg tggtggagac
    10141 cgtgcgcgac ttcctggcgg ccggcgggaa gcggatccgg gcgcttttgt gcgtggtggg
    10201 ctggcacgcc tccggtggcc atggcgatgt gacatcggcg gttcgggtgg cggcgtcgct
    10261 ggaattgttc gtggccttcg cgctcatcca cgacgacatc atggacgact cggccagccg
    10321 ccgcgggcgg cccgcggtcc accgtgtgat gcgtgcccgg ctgggaggtg gcgagcgggc
    10381 cgagcggctg ggtgcgggcg gcgcgttgct ggtgggcaac ctggccctga tgtgggcgca
    10441 ggagctgctg cacaccgctc cgatcgagtc cggccggcag cggcttgtcc atgggctgta
    10501 tgacgcgatg ctggaagagg tgatgtacgg gcagtacctg gacgtcatgg gcacgggccg
    10561 tggcgctgat gacgtcgagg cggccttacg gatcatccgc tacaagaccg ccaccgcgac
    10621 gatcgagcgg cccctgcaat tgggggctgc tgtcgccggg gccgatgacg ccacgatgga
    10681 ggtcttcacc gggctgggct tgccgctggg ggaggcgttc cagctgaggg atgacctgct
    10741 ggacgtcttc ggaagcccgg acggcgcatg cgctccgggc ctgagcgacc tgcgggaggg
    10801 caagcggacg gttctgctgg ccctgggcct gcagaatgct gacctggtcc agcgggcgcg
    10861 gcttgatcgg ctggtgggcc gggccgacct ggaggagcgt gacgcggcgg agatccggga
    10921 catcctgttc gcgacggggg cgcgcgagga gaccgagcgg atgatcactt cccgctacga
    10981 acacgtcctg cgcgtcctgg acggggccgg cttcccgccg tccgcggatc gtgctctgcg
    11041 tgggctggcg gtcaaggcca cccagtacac ttcctgaccc tgctgcgacc gcggccctag
    11101 ggcaccaaac gtcaatcgtc gcacgtctac agcggtgtca cccgactccc gagcaggaag
    11161 aactcgcgat gaccgagcag gttctcgatc gtgtctctgg atatgagcgc tggttcaaca
    11221 cgctcttcga ggagtacttc gacacgttga gcgtcgggct gggtgcgccg tcgttcagcc
    11281 gtttcactcc ggagtgcctg cggttgctgc gggagttgtc cttgcggggc gggaagcgga
    11341 tgcgggtcgt tttgctgcat gaggcggcgc gtctggtgac ggaggagccg gtcgaggggc
    11401 tggaggctgc ggcgctgagt gtcgagctgc tgcagactca cggcctggtg cacgacgatc
    11461 tcatcgacga cagccccacc cgccgcggcg gcccgtccac ttactacgcc taccgtgagc
    11521 ggtttcctgc ccggccgcag gcggcccttg gtctgaccgt gctcgcgggg gaccttgccc
    11581 tcgccctgtc gctgcgggtg ctgctggagg cgaaggtgcc tgtggcggtg cggcaggcga
    11641 tgatcgaggt gcagacgcgg gcggcggccg acacgttcgt gggccagatc gtggatctgg
    11701 aacgcgactt cgccgccgcg ccgggcgagg aggtcctgca ctgcgtggcc gactacaagt
    11761 ccgcccgcta ctcggttctc gcgcctctgc agctcgggct cctggccgct ggcgagcagc
    11821 cggcgctctt cgagaaggag ctgcgggagt atgcgcggct ggtggggatc tgcgggcaga
    11881 tgcgcgacga ctacctggat ctgttcgggg acgcatccgt catgggcaag ccgacaggca
    11941 ccgacatccg cgacggcaag cacagctaca cggtcagtgt cttgctggcg gccgtcgacg
    12001 acgccgagcg tcgcgtggtg gaggccgcgc tcggcgatcc gtcttgcctg acggagacca
    12061 tcgccgccgt tcgggagatc ggggagcgcc gtggtgtgcc gggcaggatg caggcggaca
    12121 tgcgccgctg tgcggagcag gccaccgagg tggccgccgg ctggcggtca cggtggcggg
    12181 aggaagcggt caccttcttc gaacacctgc cgctgtggag cgtcaaccgc acccggtgac
    12241 cggcccgttc agacgcctac ggggtgctgc cctggggtgg cggggccgag cgcgtcagct
    12301 ccgtgacggc ctggcgccag cgttcgggaa ggctgtcggc gccgggaagg gcggtgtcga
    12361 tgcggaagga gacgctggtg gtctcttcgt acgtcgccgc cacgacggcc agggggacgc
    12421 cgggcgggca gcacatgatg gggtcgatgc ggtgcactgc cgcctcgccg tagtgcagag
    12481 gctgacgcac cacgaggtag gaggcgcaga tggtgagccg gcccgggacg gtgctcgcgt
    12541 ccacgagaag ctggagcagt cgtcggggaa gccgggtgag ggccgctctc agcaccgtct
    12601 tgtgtccggc ggacttcagc acagaggtga cggcccgcgt gcgcgccagg cgccgctcca
    12661 ccggcatggt gccgccgggc agatcgatcc gggacagaaa cagccggttg ccggggaccg
    12721 cgacttcgtc gggcgtgcgc acgttgacgg gaaccatcac agggatcgtc gtgccagtgg
    12781 cgcggggcca agcgtccttg gcccactggg tgatcgcgtg gaccacagcg gtgaggtaga
    12841 catcgttgat gctggccccg ccgtcgcggg ccgcggcgcg cagaccggcg gagggagcct
    12901 gggcccacag caggtggcgg cggctcgaca gcggatgcga ggccgattgc cacaggcggt
    12961 gctggcgcgc gtggcgcagc aggctcacgg tgctgcgggc ggtttggcgc aggccggccc
    13021 gcgggggccg ggaggcgtcc cgggcgggcg cagggagttg gtgaggcagc gcccgcggac
    13081 cgaacagtgc atccagcacc gcgacgatgt tggcgccgtc ctgaacggcg tggtggctga
    13141 ggtagagcag agcgaacccg tcgggcacgt gaccgtgcag aaggatcatg cgccaggccg
    13201 gggcttcctc cggccacggc tctctcagcg cgtgacacac tgccgtctcg agagcctccg
    13261 gatcgccgcc ggcgtgctgg gcgcggacgt gccgggtcat gtccgggtcc gctggcatcc
    13321 accgtgcggt cggtccgttg ccggtcagga cgtgcgtcag acagggcagg ccgtccagat
    13381 gggcggtgac gtactcgcgc aggccggcga gatcgggcac agcgccggtc aggtgcagta
    13441 ctgccccgat cctcgcgttg gcgtccggat gctccgcaag ctcttcagcc ttgaccagga
    13501 cgagatcggc ggggctggga gccagaaatg ggttcatgcc catcacctca cgaggtcgaa
    13561 gacgggtgag ctgacggccg cgccgatgag gaacccgacg ctgacctggc cggcggtgtg
    13621 gcagcgcagc cggatgcggg accagccgat cagcaccacc acgggagcca gcacgagcaa
    13681 ccaggggccg aagaccgttg cgagaatggc gagggcgccg gaggcgacgg cggagtgcac
    13741 cgacaccttc cagaagaagg tgatcaccag cagggcgagc agaacggcga ccatcgccgc
    13801 caccagggcc gtcacctcga cgggagcatc cagcccatac agcagtgcgg taccgatgat
    13861 gaccgaggcc atcacccctg gggcagccac aatgcggtcc tgccgccgcc gcacatgccg
    13921 gtctccccag tactggcggt gctcgccgaa ccgaaggatc aacgtaggca gcaccgcggt
    13981 gaacaccgcc gcgatcacgc cccagccgat gccggcccag ccgtcggcgt gccagcccag
    14041 cagcggggcc aggagcagca tccagttccg gggctcgccg ccgtcactga gcagccacgc
    14101 ccagcgcgcc tccgttcgag gcaccaactc ctgcaccccc aggcgccctt ggccgggcgg
    14161 cgcggctgat gcgaccggtg aagcagccga agccgcagcc tcgtcgtccg gcaccctgaa
    14221 agcccccgtc cctcacatgg tcacgctgtc gccgtgcgcg gcgttcatcg cccaaacgac
    14281 cctcgcaccg ggccggtcac gacaccggcg cagcatgctc gacgcccgtc gacgctgccc
    14341 tggcccccgc gcgcgggagg cgggtgcggg tccgggcggc gaagacggta atgcccagcg
    14401 cagctatgcc caccgcccag cctcccccca gcagcagaca actggccggc accacccgca
    14461 gaccggcggc agccacagag gtctgcaccg cggcgtaggc cggcagcaaa cgcaccacga
    14521 gactgtccgc gtccgggttg atcagcgggt tctgcagcac cagatcaata gaactgatca
    14581 tgatggcgag aaacatgccg gccagctcgc tgcgcaccac ggccgccagc accatcccga
    14641 taccgccgta gaccagggcg ccggtgaaca tacccgcggc gagcaccagg ggctgctcag
    14701 gccgccagaa caaatgcatc cacgcggtgg tgtaggcagc gaccacggcc gagaccagaa
    14761 ggagcgcact gcacttggcg agcgcgagac ccgaccgggg aaagccagcg cgtaccaggc
    14821 gctgatcgaa cggcgcggag cggactgtgg cgacgaacat catgaacgcg atgaccagcg
    14881 acagggcctg cagcgcaccg ttgatctgga gcaggatgtt gccgtccatg accaccgtgc
    14941 ggccgaccgg acgaatccga aaccgcaagg gggcagactc caccaccgtg aacgccagcg
    15001 tggtccacag cggcacgaac aagaccacga tgagcagcgc cagccggtta cgggcctgct
    15061 cgatcagcgc gaaccgcaag gccgtacgga agcaggacca ccaccgcgtc ataccgctgc
    15121 cctccccggt tcggtctgct ccgtctcctg cagtacgcca gcctcaaggc ggtacagggt
    15181 gtccaggcgg gaggcgtcgt aggcaaggtg ggagaccacc agtaccgcgc agccccggtc
    15241 ccgcaagtcg gctgccaaat cccagaaccg caggtaggtc tcccagtcga agccctgata
    15301 cggctcgtcc aagagcagca cctgagggtc gtgcatcagg gcgaggacca ggttgagttt
    15361 ctggcgtgtg ccgccgctga gcgcgcccac ccgttcgtgc cggtagtcgc tgaagttcaa
    15421 ccgctccaac agctctaagg acctggtcag gctgctgatg ccgtaggcgg cctggaagaa
    15481 ctgcaagtgc tgctcgacgg tgaaagcctg gtgaagcacg gtgtcctgcg ggcaacagcc
    15541 cagcaggccg gcccgctcca ctacaccgcc atcagcgacg agatctccgg ccaggatgcg
    15601 cagcagggtg ctcttaccgg cgccgttctc accgacgacg cccaccagtt gacccgcaga
    15661 aaggtcaagc gacactccgc gcaggacagg acgctgccgg tagcccttcc gcacacctcg
    15721 cacccgcagc accgggtcaa gcgagctcac cactgcaccc tccacatagc tgcgcccccc
    15781 ggctcagaag ttctcgagcc ctctgtccga ccgaacgcag tcacgttctc ggcttccatc
    15841 ggtcctccag ctcactcaag gaccggcgat gcctggatcg ggctcagtcc tgcaacgatc
    15901 acggcagccc acaggacacg aatggataca cgtcggctcg gtgctgattg ggtgcgttcg
    15961 acgagggcga gatgggtcgg accggggagt cacgtcgggc agcgccacgc cctcttcacc
    16021 acttctctgg acgcaccgca gcccacactg agcccatatc tggggacgtg gtagcgacag
    16081 ggccacggcg gccttgctcg cccggacttg cagcacggag acccacagcc tttcccgagc
    16141 gggcgtcggg tctgaattgg ctgggcgcag ggctgtgtgg ttcgtcccat tgtgccctcg
    16201 tgctggctgt gagtggctgc ctgcgctctt gatcgcctga cgtgttgacg atcacggact
    16261 cccgggaacc ccggcgagcg gcggctcctc gggcgccgcg tggtggagga ccagagtcgc
    16321 cagggccttc acgtcgccca gcaccacctc caaaggcact ccggccggcc cgtacagcgg
    16381 ccagtgcacc gtgcggccgg ggtcctggag gagggtgtcg atgaggcgtt gcgtctgtgc
    16441 cagggccccg tcggtagcga tcgcggtgac cggggtgccg gccagtaggc ggccgcgagg
    16501 tccacgtagt gggtaacccg gtcgggattc ctgcggtgga cctaccaact gcttccgggc
    16561 ttcgggctgt cgggggctct ctgagcttcg ctcggctcct tggccctgcg acgtatccgg
    16621 tgaaacaccg cggactccgg ctcaggctcc ggcactccga agccgggcgg ggcctggccc
    16681 tgcagctgcg cgtacagctc ggcatttccg tcaaacgctc gacggccgca tcctgtgccg
    16741 cgaacccgga ctcctccaac tgccgcccgg ccgccgaccg ataccaaatc ctgtacgggt
    16801 ggggacactt cgaccaccac gaccgcggat gctgcgcgca ggattcgcta tgttctggaa
    16861 ctggtcgggc ggacgcagga ggagatcgaa caggcgcggc ggggctggat ggcagggtcg
    16921 cggttcggcg aggtgaaggg gtacgacggg gctccactgc ccgcgccgga gctgccgccg
    16981 gtgccgttga aaccgcgggg aagagtgcgc tgacctgcgg aaacgggtca gcgttggtgg
    17041 ccgcgtggcg ggaggtggtc gggtaactcc tgggcagctg cggcaggact cttgctgacc
    17101 tgatgcagac cttgctgacg ccttgtcagg ctcgtgggcg gcagtctgag gtatagatcg
    17161 tccggcaggg gcggagcaga agctcttggt cgggccgctg cgggagcagc ggtcggcccg
    17221 gttaatcggt tgcggacctt cggggtggag tgtctgatcc cggctatgac gattgtgctg
    17281 ggtacgccga ccgtcgacgg ggtacgcgag gccatggccg cgctgcggga gtggcagtac
    17341 gacgaagcac cgatgcagtt gcattccggg gacatcggct ggaactaccg gttcggaacg
    17401 gccgagacgg ccgcggcggt ccggacctgg agtcgggacg ggcgaattct cgcggtcggg
    17461 atgctcgact cgccttcgct ggtgcggatg acggtcgctc cggacacttt ccaggatgag
    17521 gacttggcgc ggcggctcgt cgaggacttg tcgctgcctg agcgcggcgt actgcgggaa
    17581 ggagcggtgt gcatcgaggc gccgctgggc ctgctgcttc acgacctgtt gagcaaggag
    17641 ggctggggcg tcgacgagcc gtggacgccg ctcttccgcg acctcaccga gccggtggag
    17701 gaccccggcg tgcggatcga gtcgatcggc ccggagcagg cgcaggactt cgccgacgtc
    17761 ctgcggtcgg cgttcaacac ctctcggcct acgcgcgagt actggcacgc gatgtcggcg
    17821 ggaccgttct acgccgacgc ccgctgcctg ggcgcctatg acgaccgggg cagcgtggcg
    17881 gcggtggtga cggtgtggtc ggccggcccg gggaagccgg ggctcgtcga gccgatgggc
    17941 gtccacgaga accaccgtgg tcgcggctat ggtcgggcga tcaccgtggc cggggcggcc
    18001 gcgttgcggg agatgggctc gtcgagcgta cgtgtgtgca cgccgagttc caacgtcggc
    18061 ggcgtcgcca cgtacaaggc ggccgggttc gaggtgcggc cggaggtgcg ggaccggatc
    18121 cggacggcct gacgccgggg ctgctcggca aggcggcagt ctggggcgta gatcgtctgg
    18181 caggtgcggg ttgccggtac ctcatccgcg gtctcgggtt gcgctcggac gctccggcgc
    18241 atggtgcacc ccgaggtgta tgagcggatc accgcgcgcc gcgcggagct ggatgaactc
    18301 gaagagcagc tggtcaagca gctgtccgag gtgcgggccg agtgggacga gctggccgtg
    18361 gcggtgcggc tggccccgga ccgggcgtca ggggaggacg agtccgcgct gtcggcggac
    18421 taccagcgca tccgaacagt cagtggcagc cgcccccacg aggccgctca ccgccacgaa
    18481 cacgcccacc cgcagagctg cttgacgaat cagaatgcat catggctttc cggcattgcc
    18541 tcatggaacg gcggcgtggc gtgctatacg cctgcgacga ggtcgacgag cgtggtgatc
    18601 agggcttcct cgctgactcc ggtgggctgg tgtccgaaga atcggaccga caggtggtag
    18661 ccggtgagcg cgaaggtaat gaccgccgcg agggcctccg cgtcgcgcgt cgggatcgcc
    18721 ccggctgcca tccagccggc taggcgctgc gaacggatac tgacgttgcg ggcgaccaag
    18781 agctcgccga gatggtcgac cgatgctccg agatggtcgc gctcgcgcgc gacgagctcc
    18841 atgagcgggt ggagccgccg caggttggcg agccggcgtt cgaactcgag cgcgagcgcg
    18901 atccgcacgt cgcctccggt ctcctcgggc tcggggcccg tttgccgctc ggtgtcggcg
    18961 cggtcgacct cgcggtcgac gaccgcttgg agcacctcct tcttcgaccg gaagtgccga
    19021 tagaagctgc cgctcccggc cgacagggcc gcggccgcct cgatctgcgt cacggtcgtc
    19081 ccggtgaaac cttgccgcag gaacagatcc cacgccgcgt caaggattct cgtccgcgtc
    19141 ggcactggca tgggtgcaat tgtaaggaga cggagggagc cgctgcgccc cagggccaag
    19201 gtgaccttct tgcgaaatgc aagaaggttc ttgcattgac gtcgtggaca tgccaggctg
    19261 cccaaacatg agaatccgtc acttaaccac gctcgcggga tcgttcgtcc tggcgtgcct
    19321 gccggttcag gttcacgcac tgccggtcaa ggcagcggac acgagcacgt cgtcggtcgt
    19381 ggctacgagt cagcggtcgg ggctgaactt cgatccggac aagggcaccc tcgacggctc
    19441 accggttgac catctgcccg accacatccg gctgctggac atccaacttc cgaacggcgg
    19501 cgcaccgcag cgggccgatt ggtctcccga cgggaagcgc cttgctttcc tcgacgctcc
    19561 gatcggtgac ctctgggaat acgacctggc gaccggcgcg agccgcaatc tgaccacgac
    19621 gtctgcactc cacgggggag tgctacgggc gcaccacctg accaacggcg acatcgtcat
    19681 gtgcgcggtg gctgagcgca gtgccgacga ccccgagggc gaccgcttcc gcggcgaact
    19741 gtgggtgctc cagcggcctt tgggcacacg tgccccggtc cgtctcggcg agagctgctg
    19801 ggagggcgtc gcggtgtcca agcaatctgg ttccacccgc atcgcgtgga accagtcgac
    19861 catcgacttc accaagatgc cggacgtgat caccgaagcc ctggtgggca agtcgaagat
    19921 ccttacgggt cgaatcgtct accgcaacgg caggccggag atcaccgatc ggacggttgc
    19981 cctcgacaag cgcgatgtct ccctggtcac acccgccgtt gaggctcagg acttccggtc
    20041 cctgcccgat ggggacgccg accccgacga cgaactgatc ttctccgcct actttcacaa
    20101 gggcggacag gtcatgggcg tcaacctcga caccggcgcc atcaaggact acgcgccgac
    20161 ctcgctgctc ttcgacgaag cggaaggcac cgacccggcc ggccgttaca caatggtcga
    20221 gcgagacttc gccatcgccc tgtcccccgg catggtcgac atctggcgcc tttcgctgga
    20281 tggctccggg acgttcgagc ggatgaccac gttcaaccac tacaagggct tcggggccaa
    20341 caacccggtc gtatcgcccg acggcacgca aatggccttc ggattgaaag tggagggcgg
    20401 tgccgagggc gagggcgacg gcatcctcct gatggacctc agtagatgag gaggcgttgg
    20461 cgccgactga gcgtgtccgt gctcgcccac ctcgaagcaa tgtcggaaac ctcgacctgc
    20521 gccaccagct cgacgcgctc cgtctcgtcc gccgcctcgg agtcaccgcc gtggtcgcgt
    20581 tgcgccacct caacctcgcc gcctcgtcct gcgaccgcct ctgcgcgatg cgggccggac
    20641 gcgtggtcgc ccacggcgca ccacgggacg tcctcgctcc cgccctgccg gccgacgtct
    20701 accgcgtcga ggcggacgtc accgagcatc cccgcaccgg cctgccccag gtgacactgc
    20761 tcaccggcca caacctgacc ggccgccggc ccgcacccag gcagggggcc acgcagacat
    20821 gaccgcatcc gcacccgctc gcgcgccggc cggggccgtc gccgccgcgc ctcagtctcg
    20881 cccacgggct ccccggccgc cacgccgtgc agcacctgag cgaggacctc ggcaccgcgc
    20941 acgacacgcg gcccgggccg gttgaaacgg gcaggcccat ccaggaccca gacctccccg
    21001 gcccgcccgg cgggcagttc gtcccagccc ggcagcgagg tgagcaactc gcgttcgctc
    21061 agggtgcgct cggggctgaa gccgcacggc agcacgagga cgacgtccgg ccgggcggcg
    21121 cgtacggccg cccgctccat gggcttggtg tgctcgccgg gcgccgcgag cagcggctca
    21181 gcgcccgcgc aggcgagctg ttcgggcacc cggtgcccgg ccggccacag cggatcgagc
    21241 cattcgatgg ccaccccacg ggcgcgccga cgccccgcgg tcagccgccg tacggccgcg
    21301 agccggttcc gcagccgggc tgcgctgttc ggcgacgccc cgaacaccca gcaggccccc
    21361 cacccgcacc agacagtcga gcacgtcatc caaggtgcgg ggctccggct cagcaccttc
    21421 ggcccgccgc cgtccaggac acggaccgcc tccgacaccc cgctgtagga gaccgcgcgc
    21481 acctcgcaca ggtcctgggt gagcaccacg tccggggcga gcgcggccag tgcctcggag
    21541 tcgagggtgt cgacggagcg cagcgggtga cctggggggc gtggccgccc cggtcggagt
    21601 ttcggaagtt tcgggggcct gcagaccatt gacgtggtcg acatgtcctc ttacgttcta
    21661 gcgaaccggt tcgattcatc gactggcatg cgaaatttcg aacgaaagct ggatgcagtg
    21721 gcagccgacg cccccgagac cctaaccatc gacctcggca ccgagacggg ccccttccac
    21781 ggcggcgcga gcggttcgct cttcggcctg tacggcgacg gtgtgcccag ccgcgtcctc
    21841 gtcgagggca tgtacgtccg cacgctcgcg accaaggccc aggacggcgt ccagcacccc
    21901 ggcgccgacg ccctggaggt cctccccgcc ttcgtggagt ccggtggcaa ggacgtctac
    21961 gtctacatga cggacatcta ccgcggcttc ccctacgagt ggcccggcgc aacgggcgag
    22021 gaacggctcg ccgacttcac cgcgaggatc cgaagacagg tcgaacaggt actggcgctc
    22081 gacgcgcaca agtcgcacgt cgtgtacgtg ccgttcaacg aacccgagct caacatgttc
    22141 ggcacggagg agtggagcta cgaccgggtc tcctggcgcg acgacccgcg gcactacttc
    22201 gcggcctggg agcacacgtg ccgcctcatc aggggcctg
//
