LOCUS       NZ_CP015098            21170 bp    DNA     linear   CON 03-MAR-2024
DEFINITION  Streptomyces qaidamensis strain S10 chromosome, complete genome.
ACCESSION   NZ_CP015098
VERSION     NZ_CP015098.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces qaidamensis
  ORGANISM  Streptomyces qaidamensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
REFERENCE   1  (bases 1 to 9083372)
  AUTHORS   Zhang,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-APR-2016) State Key Laboratory of Cryospheric
            Sciences, Chinese Academy of Sciences, Donggang West Road 320,
            Lanzhou, Gansu 730000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 278x
            Sequencing Technology :: Illumina HiSeq 4000; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 10:55:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,226
            CDSs (total)                      :: 8,137
            Genes (coding)                    :: 7,871
            CDSs (with protein)               :: 7,871
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 266
            CDSs (without protein)            :: 266
            Pseudo Genes (ambiguous residues) :: 0 of 266
            Pseudo Genes (frameshifted)       :: 119 of 266
            Pseudo Genes (incomplete)         :: 213 of 266
            Pseudo Genes (internal stop)      :: 25 of 266
            Pseudo Genes (multiple problems)  :: 80 of 266
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:26:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6031289
            Orig. end                         :: 6052459
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP015098.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21170
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="17"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21170
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21170
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11170](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11170
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(242..255)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.32"
                     /tool="antismash"
     misc_feature    325..339
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            complement(1397..1654)
                     /locus_tag="A4E84_RS26910"
                     /old_locus_tag="A4E84_26910"
     CDS             complement(1397..1654)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="A4E84_RS26910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_26910"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_003992873.1"
                     /transl_table=11
                     /translation="MDWRHNAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVIEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARQASA"
     misc_feature    1699..1714
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    complement(1700..1711)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     misc_feature    1877..1886
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     misc_feature    1877..1891
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.74"
                     /tool="antismash"
     gene            complement(1976..2944)
                     /locus_tag="A4E84_RS26915"
                     /old_locus_tag="A4E84_26915"
     CDS             complement(1976..2944)
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006134762.1"
                     /locus_tag="A4E84_RS26915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_26915"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_062929011.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARTRDVLIHALASEMKLEAVTTEYRGHARD
                     LGRQAADSDDIDLVVALGGDGTVNEVVNGLLHAGPAPEQLPGLAVVPGGSTNVFARALG
                     LPNDAVEATGALLDALRDGSERTVGLGLTSGTPGTEDEAVPSRWFTFNAGLGFDAGVVG
                     RVEQHRERGRKSTHALYVRQVIRQLLGEPNRRNGTITLERAGEDPVTDLVLSIVSNTSP
                     WTFLGNRPIYAAPKASFDTGLDLFGLSRLSTAAVARYGTQLLTSSPERGPHGKHATSLH
                     DLTEFTLHSKVPLPLQMDGDHLGLRTSVTFTGVRRALRVIV"
     gene            3061..3510
                     /locus_tag="A4E84_RS26920"
                     /old_locus_tag="A4E84_26920"
     CDS             3061..3510
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992875.1"
                     /locus_tag="A4E84_RS26920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_26920"
                     /product="hypothetical protein"
                     /protein_id="WP_062931632.1"
                     /transl_table=11
                     /translation="MSSEQTPTTEEATGPRPRRLTYAALLAALEGLALVVGGVWILVLG
                     LTGHPDDRQQAVTGGITLVVLALLPLLAARGLLGRRSWSRGPAVITQLMALPVAYNLLQ
                     ADSMAIPAGIALAVVAVASLVLLVNPETTRALGIRGPGNAGNVEK"
     gene            complement(3514..4650)
                     /locus_tag="A4E84_RS26925"
                     /old_locus_tag="A4E84_26925"
     CDS             complement(3514..4650)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136656.1"
                     /locus_tag="A4E84_RS26925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_26925"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_079129130.1"
                     /transl_table=11
                     /translation="MRDEERGTRELPAGGTGTSGPSGARRMADGIDGIPEQARPHPEDD
                     STGAVLPGGGRPDRDGAVRSAPPGAGVAASPAQGGPPTHEESRVAEEARARGRATGGTM
                     SEHERDSEDQAPRAHHTSGAQHGSPDRSGAREMFLKLRTLSSGSPEYAELRNQLVRMHL
                     PLVEHLARRFRNRGEPLDDLTQVATIGLIKSVDRFDPDRGVEFSTYATPTVVGEIKRHF
                     RDKGWAVRVPRRLQELRLALTTATAELSQLHGRSPTVHELAEKLAISEEEVLEGLESAN
                     AYSTLSLDVPDTDDESPAVADTLGAEDEALEGVEYRESLKPLLEDLPPREKRILLLRFF
                     GNMTQSQIAQEVGISQMHVSRLLARTLAQLREKLLVEE"
     gene            complement(4668..5081)
                     /locus_tag="A4E84_RS26930"
                     /old_locus_tag="A4E84_26930"
     CDS             complement(4668..5081)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="A4E84_RS26930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_26930"
                     /product="hypothetical protein"
                     /protein_id="WP_003992877.1"
                     /transl_table=11
                     /translation="MSQIAGEPATQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGHAPSRDTFAWTV
                     LSALAGKVSSAVDKDKTVSISLYKQRGAGPGPA"
     gene            complement(5342..5602)
                     /locus_tag="A4E84_RS41235"
     CDS             complement(5342..5602)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571357.1"
                     /locus_tag="A4E84_RS41235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_079129131.1"
                     /transl_table=11
                     /translation="MKQCTHAEALPHPEPGPLSETCPECLAEGMDPVQLRLCLSCGHVG
                     CCDSSPGRHAAEHHKESGHPVMRTHEPGETWRWCFVDHVLV"
     misc_feature    complement(5639..5648)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.67"
                     /tool="antismash"
     gene            5665..7263
                     /locus_tag="A4E84_RS26935"
                     /old_locus_tag="A4E84_26935"
     CDS             5665..7263
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072182.1"
                     /locus_tag="A4E84_RS26935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_26935"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_062929012.1"
                     /transl_table=11
                     /translation="MDVMPLLLLVAGSAAIAAAARRTPVPAPLLLVAVGLAVSYVPGVP
                     EYTLDPHIVLPLILPPLLHTAAIESSYLDLRAQLRPVAMLSVGYVLFATFVVGWAVYVI
                     VPDMPLTAALVFGAVVAPPDAVAATAVARRVGLPSRITTILQGESLLNDATAITAYRVA
                     LAAAVGEGATWAGGIGEFLLAAIGGVVVGLLLMAPIHWLRTHVKEALLQNTLSLLIPFV
                     AYAVAEQVHASGVLAVVVVALYLGHRAWEVDFATRLQEEAVWKMVAFVLESAVFALIGL
                     QLPVVLKGLGEYEGVEAAWYAAAVFLVVVAARFVWVYPATFLPRLLSARVREREQDPTW
                     KGPFVIAWAGMRGVVSLAIAFSIPLTLHDGEEPFPQRNLILFLTFTTVIGTLVVQGLTL
                     PPLIRLLKLPGREAQTETLAEANAQAQASRAAERRLDELLTDERNTLPAPLADRLRIVL
                     ERRRNAVWERLGQANPITGESVDDTYRRLAREMISAEREVFVKLRDARYIDDEMLRTLL
                     RRLDLEEAAAFREAA"
     gene            complement(7318..8226)
                     /locus_tag="A4E84_RS26940"
                     /old_locus_tag="A4E84_26940"
     CDS             complement(7318..8226)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016824664.1"
                     /locus_tag="A4E84_RS26940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_26940"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_062929013.1"
                     /sec_met_domain="PALP (E-value: 1.1e-15, bitscore: 56.7,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPDTPGLAALRPRLPSPLQEVVDGRFERRGVRLLLKRDDLIHP
                     ELIGNKWRKLAPNLTVAAGRTVVTFGGAWSNHLRATAAAGRLLGIPTVGVVRGDELAGR
                     PLNPSLARCTADGMRLHFVDRAMYRRKTEPPVLAGILRAADAEEAYVVPEGGSNAEAVR
                     GCRALGTELRGRAETVAVACGTGGTLAGLAAGLACGQRALGVPVLRGGFLTAETEALQG
                     AAFGGRRGTWSLDDRFHCGGYARVPAELDAFAADFEQRHGLPVERLYVAKLLYGLVTLA
                     GEGAFARGTAVAAVVTGRPFP"
     misc_feature    8228..8240
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            8483..9889
                     /locus_tag="A4E84_RS26945"
                     /old_locus_tag="A4E84_26945"
     CDS             8483..9889
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="A4E84_RS26945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_26945"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_062929014.1"
                     /transl_table=11
                     /translation="MSVGEEVRTEQTKPQQSLGTAAARNLATTTKSVPQMQEISSRWLL
                     RMLPWVDIQGGTYRVNRRLTFAVGDGRLTFVKTGDRVEIIPAELGELPALRSYDDEEVL
                     FEISRRCEQREIPAGDVIASFGSPSDEVYLLAHGRVEKVGTGPYGEDESLGVLADGAYF
                     GDDALLNEDAIWEYTARALTACTVLVLPRQEFEQIAERSDTLREHLQQRRSIPSQRSNK
                     YGEKEIDLSSGHSGEPDIPHTFVDYEARPREYELSVAQTVLRIHTRVADLYNQPMNQTE
                     QQIRLTVEALKERQEHELINNRDFGLLHNCEYDQRIQPHDGVPGPDDLDELLSRRRGTK
                     MLLAHPRAIAAFGRELNQRGLVPETIDMAGNRIPTWRGVPIFPCNKIPVSDARTTSIIA
                     LRTGEADQGVIGLRASGIPDEIEPSLSVRFMGINEQAIIKYLVTAYYSAAVLVPDALGV
                     LENVEIGRWR"
     misc_feature    complement(9931..9947)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.91"
                     /tool="antismash"
     misc_feature    complement(9932..9947)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.0"
                     /tool="antismash"
     gene            10001..11170
                     /locus_tag="A4E84_RS26950"
                     /old_locus_tag="A4E84_26950"
     CDS             10001..11170
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047517.1"
                     /locus_tag="A4E84_RS26950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_26950"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_062929015.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.7e-59, bitscore:
                     199.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGESLTKSRRGTTQPARGGQRGAEPRPSAGAPQRQGGIGTQGDGG
                     PQPAEGHEAVMLLERARAEVDPVLRAALGSLPAPMRRVALHHFGWEQADGTPADGGSGK
                     AIRPALVLAAAAALGGPEARAGAARAAAAVELVHNFTLLHDDVMDRDTTRRHRPTAWTV
                     FGDADAILAGDTLQALALRLLAQDPHPASSAAAARLADCVVELCAGQHADTAMERCAPG
                     EVTLDEVLAMAEAKTGALIGSACAIGGLYAGASDEEVAALDAFGREAGLAFQLIDDVIG
                     IWGDPRRTGKPAGADLAARKKSLPVVAAFASGTPAAAELAELYARTSEKEDLDHIALTV
                     ERAGGRDWAQGQAADRMARAMQQLARAVPDPEAAGGLLALAEFVTRRSS"
     gene            11494..12105
                     /locus_tag="A4E84_RS26955"
                     /old_locus_tag="A4E84_26955"
     CDS             11494..12105
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444621.1"
                     /locus_tag="A4E84_RS26955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_26955"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_062929016.1"
                     /transl_table=11
                     /translation="MGVAIRTAGAEDRELIVRLLDEAFQDDPVSGWVFPRVEDRRAKHP
                     RLMAAFTDIVLAAGRIDVTEDGSACALWLSMPADEGHDDAEDEGPAQVREAVDPGNERV
                     ESIGRLVAAVHPTGRAHEYLWMIGVAPGRQDEGIGTALIEAVLDRCDREGLPAYLEASN
                     VRSRNLYERLGFEPAGPALNLPDGPSMWPMWREPRPQRPA"
     gene            <12494..12565
                     /locus_tag="A4E84_RS45510"
                     /pseudo=""
     CDS             <12494..12565
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040419.1"
                     /locus_tag="A4E84_RS45510"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="dihydrofolate reductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="EFALESVRTFGNGALVRTYSRKR"
     gene            12592..12867
                     /locus_tag="A4E84_RS44760"
     CDS             12592..12867
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925795.1"
                     /locus_tag="A4E84_RS44760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_079129132.1"
                     /transl_table=11
                     /translation="MGSEGYVCPDCGQPVETVVRRHKTLGTWVPRWVAGPCRNPECGAC
                     ETQGADSGRTAQGTRPGPAPAVPGDTAPPATTPLEPASGDTAAKNP"
     gene            12953..13366
                     /locus_tag="A4E84_RS26960"
                     /old_locus_tag="A4E84_26960"
     CDS             12953..13366
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007384635.1"
                     /locus_tag="A4E84_RS26960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_26960"
                     /product="YciI family protein"
                     /protein_id="WP_062929017.1"
                     /transl_table=11
                     /translation="MKYLVMVQGTQADYDAMRGKASAHSPAWSEEELQTMFAYMGAIND
                     DLAETGELVDGQGLAEPAQTRHVTLGDDGKAVITDGPYSETKELLAGYWVLECESLERV
                     TEIADRVARCPQPAGAPDYPVVIRPIMDGSGDI"
     gene            13406..14626
                     /locus_tag="A4E84_RS26965"
                     /old_locus_tag="A4E84_26965"
     CDS             13406..14626
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040410.1"
                     /locus_tag="A4E84_RS26965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_26965"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_062929018.1"
                     /transl_table=11
                     /translation="MRNPPEIEDLLRRDAPQVLGALVRRYGHFDAAEDAVQEALLAAAG
                     QWPEAGVPGNPRGWLIKVASRRLTDALRSDQARRQREERAAALTPRDAFTAPPPGERAP
                     REDDTLSLLFLCCHPDLSPSAQIALTLRVVGGLTTAEIARACLVPESTMAQRVSRAKQK
                     VRGVRFGRPDRWEQRLPSVLQTLYLIFNEGYTATSGAALQRRDLAGEAVRLTRAVHRLL
                     PGDCEVAGLLALMLLTDARRDARGGPRGELIPLDEQDRGRWDRAAIEEGVALVTRALSR
                     GRPGPFQLRAAIAAVHDEAPSPGSTDWAEILGLYDVLVGLLPGPVERLNRAVAVAMVHG
                     PRAGLTEVDALEGELKGHRLDAVRGHLLERVGEPEAARAAYESAAAQTLSLPEQRYLRA
                     RAARLSD"
     gene            14637..14876
                     /locus_tag="A4E84_RS26970"
                     /old_locus_tag="A4E84_26970"
     CDS             14637..14876
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123527.1"
                     /locus_tag="A4E84_RS26970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_26970"
                     /product="hypothetical protein"
                     /protein_id="WP_063827518.1"
                     /transl_table=11
                     /translation="MGIPGERRRTVWPGVVIGWALIVAVTGGLTLWMQDSAEPAGPYVW
                     ERTNPYEPPDLPPCPTPEGAGAADCAYGTYTKRG"
     gene            complement(14945..15694)
                     /locus_tag="A4E84_RS26975"
                     /old_locus_tag="A4E84_26975"
     CDS             complement(14945..15694)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657876.1"
                     /locus_tag="A4E84_RS26975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_26975"
                     /product="VOC family protein"
                     /protein_id="WP_062929020.1"
                     /transl_table=11
                     /translation="MRISWTYAFIDRPRDAFGTACDFWTAVTDTRLSAPRGEHDEFVTL
                     LPTSDGADACVKVQAVGPGPGGAHIDFCVDDVPEFAAAAVRRGADVVADLGSLVVLRSP
                     GGQLFCADPWRGQSSRPGVVRGSRLDQVCLDVPSSAYDREVGFWSALLDGWESLPGALP
                     EFHVVKPPPGLPVRLLLQRLGEERPASAHLDLACADVAATRARHEALGAVFVSGFSGWT
                     VMRDPAGGTYCLTTRDPVTGGLRGQER"
     gene            15799..16953
                     /locus_tag="A4E84_RS26980"
                     /old_locus_tag="A4E84_26980"
     CDS             15799..16953
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058926.1"
                     /locus_tag="A4E84_RS26980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_26980"
                     /product="inorganic phosphate transporter"
                     /protein_id="WP_062929021.1"
                     /transl_table=11
                     /translation="MDHITFLVAVVIVTALAFDFTNGFHDTANAMATSIATGALAPRTA
                     VLISGVLNVVGAFLSTEVARTISGGIVDDTLVSPGMIFAGLVGAILWNLLTWLVGLPSS
                     SSHALFGGLIGAVWVGAGSHGVHFGKVVEKVLVPAVASPVVAGVAALLATYLAYRLTDR
                     AGKDSVTRGFRIGQVASASLVSLAHGTNDAQKTMGVITLTLISAGALGHDAGPPLWVIA
                     SAGLAIGLGTYLGGWRIIRTMGRGLTEIQSPQGFAAETASTTVILTSAHLGFALSTTQV
                     ASGSILGAGLGRRLAEVRWGVAGRMAVAWVITLPAAALVGGLAAAVVQNGGDLGTAVVA
                     MVGAALAAGIVVISRRNPVHAHNVNDAHEVSIRTEPPAKVGAAA"
     gene            16969..17202
                     /locus_tag="A4E84_RS26985"
                     /old_locus_tag="A4E84_26985"
     CDS             16969..17202
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123531.1"
                     /locus_tag="A4E84_RS26985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_26985"
                     /product="hypothetical protein"
                     /protein_id="WP_062929022.1"
                     /transl_table=11
                     /translation="MHLDWTALGQVAAVSVGATVAVVVVFALGVLGLARLEGTRALRGG
                     TFALGLTQAVLCFLACAAVVAYGIYLIVPQLH"
     gene            complement(17270..17665)
                     /gene="sodN"
                     /locus_tag="A4E84_RS26990"
                     /old_locus_tag="A4E84_26990"
     CDS             complement(17270..17665)
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="A4E84_RS26990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_26990"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_031140564.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVKVSAHCDLPCGVYDPAQARIEAESVKAVQEKMAAN
                     DDPHFQARATVIKEQRAELAKHHVSVLWSDYFKPPHFEKYPELHQLVNDTLKALSAAKG
                     STDPATGQKALDYIAQIDKIFWETKKA"
     gene            17811..18245
                     /gene="sodX"
                     /locus_tag="A4E84_RS41245"
     CDS             17811..18245
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925778.1"
                     /locus_tag="A4E84_RS41245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_159029622.1"
                     /transl_table=11
                     /translation="MPELSQESERGRPAPPFGVAEVTGPSMVPTLYHGDRLLVHYGGRV
                     RPGDVVVLRHPFQQDLLVVKRVAQRRESGWWVLGDNAYAGGDSTDYGVVPDDLVLGRVR
                     FRYRPRGSGRRSPWALLGWALSAARPVLSDRSASRRLRAR"
     gene            complement(18128..18778)
                     /locus_tag="A4E84_RS26995"
                     /old_locus_tag="A4E84_26995"
     CDS             complement(18128..18778)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925775.1"
                     /locus_tag="A4E84_RS26995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_26995"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_062929023.1"
                     /transl_table=11
                     /translation="MELAYYSDYAVRLVNTEEPARGKDALTSVEAVRDLFGPSQSAARR
                     ATDADVTRFRSVRARLRAVFEAADAGEERLAVDLLNSLLLEFPVSPQVSGHDVRDDDGR
                     PLWHMHLADHPSNATAGYAAIAAMGLAFHLTEYGVDRLGLCEAAPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRLEADRSERTGLAADSAQPSSAQGDLRPDPRGR"
     misc_feature    18771..18786
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     gene            18868..19638
                     /locus_tag="A4E84_RS27000"
                     /old_locus_tag="A4E84_27000"
     CDS             18868..19638
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983528.1"
                     /locus_tag="A4E84_RS27000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_27000"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_062929024.1"
                     /transl_table=11
                     /translation="MTDADITTTTADWQAWQESWDRQQEWYLPDREERLRIMLDMVEAT
                     VGTAPRVLDLACGTGTITARLLARFPDATSTGVDLDPALLAIAEGTFASDDRVTLVTAD
                     LKDPDWPARLPHDSYDAVLTATALHWLHREPLADLYGQVAGLVRAGGVFMNADHMIDES
                     TPRINAAERAQRHARMEQARESGVLGWTEWWQLAAKDPVLAGPTARRYEIYGDHADGDM
                     PSVQWHARMLREKGFGEARPVWCSPSDTLLLAMR"
     gene            complement(19704..20465)
                     /locus_tag="A4E84_RS27005"
                     /old_locus_tag="A4E84_27005"
     CDS             complement(19704..20465)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973712.1"
                     /locus_tag="A4E84_RS27005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_27005"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_033313541.1"
                     /transl_table=11
                     /translation="MTAMVKAEGVHKSFGPVEVLKGIDLEVKSGEVFCLIGPSGSGKST
                     FLRCINHLEKINAGRLYVDGELVGYRQKGDKLYELKDSEVAVKRRDIGMVFQRFNLFPH
                     MTAVENVMEAPVQVKGVSRSQARTRAQELLDRVGLADKAGNYPSQLSGGQQQRVAIARA
                     LAMDPKLMLFDEPTSALDPELVGDVLDVMRDLAESGMTMIVVTHEMGFAREVGDSLVFM
                     DGGVVVESGHPREVLTNPQHERTKSFLSKVL"
ORIGIN
        1 cgaccccgag tggcgcgagg aggtgcccgt ccgggtcgag tcgatccccg tacggcggga
       61 aggacgcgtc ctcggcgtca tcgcgcgcaa caccaatctc ctcaccgtgc gcaccccgag
      121 ccgcctggag ctcacctatc tgcagagcgc ctccgacctc gcgcagatga tcgcggccgg
      181 gtccttcccg ttcgcgaacc agcagctcga catggacgcc tcgccccgtg tgggcgacgg
      241 cctgatccgg ctcgacgccg acgccatcgt ccagtacgcc tcgccgaacg ccctgtccgc
      301 ctaccaccgg ctcggcctcg cctccgacct cgtcggccag cacctgggca agaccaccgc
      361 cgaactcgcc ccgacccggg gcccggtgga cgaggcgctg gccaaggtcg ccagcggctg
      421 ggcgccgcgc gagttcgaga tcgaggccag tgacggggtc atccagttcc gtgcgatccc
      481 gctcaaaccg aagggcaccc gcatcggttc cctcgtcctg ctccgggacg tcaccgaact
      541 gcgtcgacga gagcgcgagt tgatcaccaa ggacgcgacg atccgggaga tccaccaccg
      601 cgtcaagaac aacctccaga cggtggcggc gctgctccgc ctccaggccc ggcgcatcga
      661 gtccgaccgc gggcgtgagg ccctcgaaga ggcggtacgg cgtgtcggat cgattgcgat
      721 cgtgcatgag acgctctccc agaacctgga cgagcgggtg gagttcgacg acatcgccga
      781 ccgtgtgctg gccatggtcg cggagatctc cccgggcaag gtcgccggcc ggcgcaccgg
      841 acgcttcggc atcctggacg ccgaggtcgc gacgccgctg tcgatggtgc tgaccgaggt
      901 gctgcagaac gcgctggagc acggtttccg tgagggcgac accggcacgg tcgaggtctc
      961 ggcggtccgc ggcggcacga gcaaggaggc ccgactgctg gtcacggtcc aggacgacgg
     1021 ggtcggcctg ccggaagggt tcgatccgca caccgcaggc aatctcggcc tgcagatcgt
     1081 gcggaccctg gtggaggggg agttgggcgg caccttcgac atggtcccgg ctccggagcg
     1141 cggcacccgc gtgatcctcg acatcccggt gcggtcgcag aagtagtgga gcccgagcct
     1201 cggaacgggg gccggaaaag caatgagccc cgggccacca agtggcccgg ggctaaagct
     1261 cgttgctgct taactaagcg catcggggga actgcgcgct gcggctcggg ggcgggagat
     1321 gcgtactcgc tgtctacgaa gtaatgccgt aaggcacacg cgccgccaag ctcaggctgt
     1381 cagcaggggt gggttgtcag gcggaggcct gacgggcccg gttgcgggcg gcgcggcgct
     1441 tcatcgcgcg gcgctcgtcc tcgctgagac caccccagac gccggagtcc tggccggact
     1501 cgagcgccca ctgcaggcac tgctcgatca ccgggcagcg acggcagacg gccttggctt
     1561 cctcgatctg cagcagcgca ggaccggtgt tgccgatggg gaagaagagc tcggggtctt
     1621 cctcgcggca aacggcgttg tgacgccagt ccatggctgc tacctctcct tggtattacg
     1681 tgcaggtttg cttgtgaatg tgaacgcttt cacgaatccc tcaacaagtg aagggccgac
     1741 tgccaggttc cccggcgaag gtcctgtgat gtgaagaggg gttctggtga tcagtggagg
     1801 ccggtgttgc gggccgtctc gatcgccacg tagagactcg caaacctcag cggcggatac
     1861 aaccccttct ggaaagtttt ttttgattct tcggtgtcga ctaggtcaca gccgtacttc
     1921 catggggtgg atcctggcct aaacgttcga gtgaaaggac tttagccagt tctgctcaca
     1981 caatcacacg cagtgcacgg cgtacgcctg tgaacgtcac gctagtccgc agccccaggt
     2041 ggtcaccgtc catctggagg gggagcggga ccttcgaatg caaggtgaac tctgtcaagt
     2101 catgcagaga ggtggcgtgc ttgccatggg gtccgcgctc gggggacgaa gtgagcaact
     2161 gggtgccata ccgggcaaca gccgcggtgg acagacggct gagaccgaag agatcgaggc
     2221 cggtatcgaa cgaggcttta ggcgccgcgt agatcgggcg attccccaga aacgtccatg
     2281 gcgaggtgtt cgagactatg gacagcacca gatcagtgac cggatcctcg ccggcccgct
     2341 ccagcgtgat cgtcccgttg cggcgattcg gttcgccgag gagctggcgt atgacctggc
     2401 gcacgtagag agcgtgtgtg gatttccggc cgcgctcgcg atgctgctcc acacgaccca
     2461 ccacaccggc gtcgaagccg agtcccgcgt tgaaggtgaa ccagcgggac ggcaccgcct
     2521 cgtcctccgt gcccggagtg cccgaggtca gtccgaggcc gacggtccgt tcgctgccgt
     2581 cgcgcagggc gtccagcagg gcgccggtgg cctccacggc gtcattgggc aggcccaggg
     2641 cgcgggcgaa gacgttggtg gagccgcccg ggaccacggc gaggccgggc agctgctccg
     2701 gagcggggcc ggcgtgcagc aggccgttga ccacttcgtt gaccgtgccg tcgccgccga
     2761 gggccaccac caggtcgatg tcgtcgctgt ccgccgcctg ccggcccagg tcgcgcgcgt
     2821 gaccgcggta ctcggtggtg accgcctcca gcttcatctc gctggcgagc gcatggatca
     2881 gtacgtcgcg tgtgcgcgca ctcgtagtgg ttgccgccgg attgaccacg agaagtgcac
     2941 gcatgactgg cagcgtacct actgggtggt accgggccca taccgaggta gtgatcaggt
     3001 aagagagcag aggtgaaccg caccccgggg ggcgtgtacg acgggcgcta ctcttcaggg
     3061 gtgagcagtg agcagacccc caccaccgag gaagccaccg gcccccgccc ccggcgtctg
     3121 acgtacgccg cgctgctggc cgcactggag gggctcgcac tggtcgtcgg aggcgtctgg
     3181 atcctcgtcc tcggcctcac gggccatccg gacgaccggc agcaggcagt gaccggaggc
     3241 atcacgctgg tcgtgctcgc gctgctgccc ctgctcgccg cgcgcgggct gctcggccgc
     3301 cgcagctgga gccgcggccc ggccgtcatc acccagctca tggcgctgcc ggtggcctac
     3361 aacctgctgc aggccgacag catggccatt ccggctggga tcgccctcgc cgtcgtggcc
     3421 gtagcgtcgc tcgtcctgtt ggtgaacccc gagacgaccc gggccctcgg gatccgcggg
     3481 cccggcaacg ccggcaacgt ggagaagtag ccgtcactcc tcgacgagga gcttctcccg
     3541 cagctgcgcc agcgtgcgcg ccagcagccg ggagacgtgc atctgcgaga tgccgacctc
     3601 ctgcgcgatc tgcgactggg tcatgttgcc gaagaaccgc agcagcagaa tccgcttctc
     3661 acgcggcggg agatcctcca gcagcggctt gagggactcc cggtactcca cgccctccag
     3721 cgcctcgtcc tcagcgccga gggtgtccgc gaccgccggg gactcgtcgt cggtgtcggg
     3781 gacgtccagg gacagcgtgg agtacgcgtt ggcggactcc aggccctcca ggacctcctc
     3841 ctccgagatc gccagcttct cggcgagctc gtggaccgtg ggagagcgac cgtgcagctg
     3901 cgagagctcg gccgtggccg tggtcagcgc caggcgcagc tcctgcagcc ggcgcggcac
     3961 gcgcaccgcc cagcctttgt cgcggaaatg ccgcttgatc tcgccgacga ccgtcggagt
     4021 cgcgtacgtc gagaactcca cgccgcggtc cgggtcgaat cggtccaccg acttgatgag
     4081 gccgatggtt gcgacctggg tgaggtcgtc cagcggctcc ccgcggttgc ggaagcggcg
     4141 cgcgagatgc tccaccagcg gcagatgcat ccggaccagc tggttgcgca gctccgcgta
     4201 ctcggggctg ccgctgctca gggtgcgcag cttgaggaac atctcgcgcg cgccgctgcg
     4261 gtccggagag ccgtgctgcg cacctgatgt gtggtgtgcg cgcggcgcct gatcctcgga
     4321 gtctcgctcg tgctcgctca tcgtcccgcc cgtcgccctt ccccgagccc tcgcctcctc
     4381 cgccactctc gactcctcgt gagtgggggg acccccctgg gccggggatg cggcgacccc
     4441 cgcgcccgga ggcgcgctcc gcacggcacc gtcccggtcc ggccgcccgc cgcccgggag
     4501 gacggccccc gtggagtcgt cctcggggtg cgggcgggcc tgctcgggga tgccgtcgat
     4561 gccgtccgcc atgcgccggg cgccgctcgg gccgctcgtg cccgtgcccc cggccggcag
     4621 ctctcgtgtg ccgcgctctt cgtcccgcac cggcccgtcc tcgctcctca cgccggcccg
     4681 ggtcccgcgc cgcgctgttt gtagaggctg atcgaaacgg ttttgtcctt gtccacggca
     4741 gaggagacct tgcccgcgag ggcggacagg accgtccagg cgaaggtgtc ccgcgacggg
     4801 gcatggccat ccgtggtggg tgccgagacg gtgacctcga gcgagtcgtc gacgaggcgg
     4861 aagacacagc tgagcaccga gccgggcacg gcctgctgaa gcaggatcgc gcaggcctcg
     4921 tccaccgcga tgcgcaaatc ctcgatctcg tcgagggtga agtccaaacg ggccgcgaga
     4981 ccggccgtgg ccgtacgcag caccgacagg taggcacccg cggccggcag ccggacttcc
     5041 acgaagtcct gggtcgcggg ctcgcctgcg atctgggaca ccctcacctc catggtggta
     5101 caagcgtttc agggccgagg gtcgcccccc ggggtaacgc gatacgtggt tcagcggtga
     5161 cgctatcgcg ctcttgacgg tcctgtcccc gggaccccaa ccccttgtcg ttactcacag
     5221 taaacctgtg gatacgctcc gtgtctagag gttgggcggg cccaaatggg aagagcgcgc
     5281 gccgggttga cgtacccaga cgtcagacgg tcgaaccgtc cggcgccggg gtcctgtcgc
     5341 gtcacaccag gacatggtcg acgaagcacc aacgccaggt ctctccgggt tcgtgggtcc
     5401 gcatcacggg gtgaccggac tccttatgat gctccgccgc gtgccgtcct ggcgaggagt
     5461 cgcagcagcc gacgtgaccg cagctgaggc acagccgtag ttgcaccgga tccatgccct
     5521 ccgccaagca ctccggacac gtctcgctga gcgggccggg ttcggggtgc ggcagcgcct
     5581 cggcgtgcgt gcactgtttc atgattgcca ggttacgacg gtcgggcgga agaccgcgtc
     5641 gaaaaacgag ggcgggcgag aacgatggac gtgatgccac tgctgctgct cgtggcgggc
     5701 agtgccgcga tagccgcggc ggcgcggcgc accccggtgc cggcgccgct gctgctggtg
     5761 gccgtggggc tggcggtgag ctacgtcccc ggggtgcccg agtacacgct cgacccgcac
     5821 atcgtgctgc cgctcatcct gcccccgctg ctgcacacgg ccgccatcga gagttcctac
     5881 ctcgacctgc gggcgcagct gcggccggtc gccatgctgt ccgtcgggta cgtgctgttc
     5941 gcgaccttcg tggtcggctg ggccgtctac gtgatcgtgc cggacatgcc gctgaccgcg
     6001 gccctggtct tcggcgcggt ggtggcgccc ccggacgcgg tcgcggcgac ggcggtggcc
     6061 cggcgggtcg ggctgccgtc gcggatcacg acgatcctcc agggcgagtc cctgctgaac
     6121 gacgcgaccg cgatcaccgc ctaccgggtg gccctggccg ccgccgtcgg agagggcgcg
     6181 acctgggccg ggggcatcgg cgagttcctg ctggcggcga tcggcggcgt cgtggtgggc
     6241 ctgctgctga tggcaccgat ccactggctg cgcacgcacg tgaaggaggc gctgctgcag
     6301 aacacgctct ccctgctgat ccccttcgtc gcgtacgccg tcgccgagca ggtgcacgcc
     6361 tcaggtgtcc tcgcggtcgt ggtcgtggcg ctctacctgg ggcaccgcgc gtgggaggtc
     6421 gatttcgcca cgcgtctgca ggaggaggcg gtctggaaga tggtcgcctt cgtcctggag
     6481 tcggcggtct tcgcgctgat cggactgcag ctcccggtgg ttctcaaggg cctcggcgag
     6541 tacgagggcg tcgaggcggc ctggtacgcg gccgccgtct tcctggtcgt cgtcgcggcc
     6601 cggttcgtct gggtataccc ggccaccttc ctgccgcggc tgctgtcggc ccgggtgcgg
     6661 gaacgtgagc aggacccgac ctggaagggg cctttcgtca tcgcgtgggc cgggatgcgg
     6721 ggcgtggtct cgctggccat cgccttctcg atcccgctca ccctgcacga cggtgaggag
     6781 cccttcccgc agcgcaacct catcctcttc ctgaccttca cgacggtcat cgggactctg
     6841 gtcgtgcagg gcctgacgct gcccccgctg atccggctgc tgaagctccc ggggcgggaa
     6901 gcccagaccg agacgctcgc cgaggccaac gcccaggcgc aggcctcccg agccgccgaa
     6961 cggcgcctgg acgagctcct gaccgacgag cgaaacaccc tgcccgcccc gctcgccgac
     7021 cggctgcgca tcgtcctgga gcgccgccgc aacgccgtct gggagcggct cgggcaggcc
     7081 aacccgatca ccggggagtc cgtcgacgac acctaccgac ggctggcgcg cgagatgatc
     7141 agtgccgagc gcgaggtgtt cgtcaagctc cgggacgccc gctacatcga cgacgagatg
     7201 ctgcggaccc tgctgcgcag actggacctg gaggaggcgg cggccttccg ggaggcggcg
     7261 tgacgccgga gcggcacctc cgacggagca atacctcagg gggagcggag cggcacctca
     7321 ggggaagggg cggccggtga ccacggccgc caccgccgtc ccccgcgcga aggcgccttc
     7381 accggccagg gtgaccagcc cgtacagcag cttggcgacg taaagccgtt cgacgggcag
     7441 gccgtgccgc tgctcgaagt ccgccgcgaa ggcgtcgagc tcggcgggca cgcgcgcgta
     7501 gcccccgcag tggaaacggt cgtccaggct ccaggtgccg cgccgaccac cgaaggccgc
     7561 accctgcagg gcttccgtct cggcggtcag gaagccgccc ctgagcaccg gcacgcccag
     7621 ggcgcgctgg ccgcaagcga ggccggcggc cagtcccgcg agcgtgccgc cggtgccgca
     7681 ggccacggcg acggtctcgg cgcgcccgcg cagctcggtg ccgagcgccc ggcagccccg
     7741 caccgcctcg gcattgctgc cgccctcggg gacgacgtag gcctcctcgg cgtccgccgc
     7801 gcgcaggatg ccggccagga cgggcggctc ggttttgcgg cggtacatcg ccctgtcgac
     7861 gaagtgcagc cgcatgccgt cggccgtgca gcgggccagt gaggggttga gaggccggcc
     7921 ggccagttcg tcaccgcgga cgacaccgac cgtggggatg ccgagcagcc ggccggccgc
     7981 ggccgtggcg cgcagatggt tggaccaggc tccgccgaag gtgacgacgg tccggccggc
     8041 cgccacggtc aggttcggcg cgagcttgcg ccacttgtta ccgatcagct ccggatggat
     8101 cagatcgtcc cgcttcagca gcagccgcac gccccggcgc tcgaaccggc cgtccacgac
     8161 ctcctgcaac ggcgagggga gccgggggcg cagcgcggcg agtccggggg tgtcggggct
     8221 ggtcaccggg tcattgtcac ccgggagtgt gagggaggga gcgcggggac cgacgggagg
     8281 ctctggggcc ggacaccccc agcccggtcg cggacgcgcg tgccttcgaa cgccgtgacg
     8341 ggccccctct gcccagcggc gcaaagatcc attcccgctc tttcgtgtaa tagcaccgcg
     8401 acgtcgagtg aggaaggctt gctcgtgcac atcgatgccc gggtcgtatg ggcgtcggtc
     8461 acaaccggga gggcagttct ctatgtcggt aggcgaagag gtccgcacgg agcagaccaa
     8521 gccgcagcag agtctcggca cggcggccgc gcggaacctg gccaccacga ccaagtccgt
     8581 gccacagatg caggagatca gctcccgctg gctgctgcgg atgctgccgt gggtcgacat
     8641 ccagggtggt acgtaccggg tgaaccggcg gctgacgttc gccgtgggcg acggccggct
     8701 gacgttcgtg aagaccggcg accgcgtcga gatcatcccc gccgagctgg gcgagctccc
     8761 ggcgctgcgg tcgtacgacg acgaggaggt gctcttcgag atctcccgcc gctgcgagca
     8821 gcgggagatc ccggcaggcg atgtcatcgc ctcgttcggc agcccgtccg acgaggtgta
     8881 cctcctggca cacggcaggg tggagaaggt cggtacggga ccgtacgggg aggacgagtc
     8941 cctcggagtc ctcgccgacg gtgcctactt cggtgatgac gcgctgctga acgaggacgc
     9001 gatctgggag tacaccgccc gggccctcac cgcgtgcacc gtgctcgtgc tgccccgcca
     9061 ggagttcgag cagatcgcgg agcggtcgga caccctgcgc gaacacctcc agcagcgccg
     9121 ctccatcccc tcgcagcgct ccaacaagta cggcgagaag gagatcgacc tctcctccgg
     9181 ccactccggc gagccggaca tcccgcacac cttcgtcgac tacgaggccc ggccccgtga
     9241 gtacgaactg agcgtcgccc agaccgtgct gcgcatccac acgcgcgtag ccgacctcta
     9301 caaccagccc atgaaccaga ccgagcagca gatccggctg acggtcgagg cgctgaagga
     9361 gcgccaggag cacgagctca tcaacaaccg cgacttcggg ctcctgcaca actgcgagta
     9421 cgaccagcgg atccagccgc acgacggcgt gcccgggccg gacgacctgg acgagctgct
     9481 cagcaggcgc cgcggcacca agatgcttct cgcccacccg cgcgccatcg ccgcgttcgg
     9541 ccgcgaactc aaccagcgcg ggctggtccc cgagaccatc gacatggcgg gcaaccgcat
     9601 cccgacctgg cgcggtgtgc cgatcttccc gtgcaacaag atcccggtct cggacgcccg
     9661 tacgacgtcc atcatcgccc tgcgtaccgg cgaggccgac cagggcgtca tcggtctgcg
     9721 tgcctccggc atccccgacg agatcgagcc gagcctgtcg gtccgcttca tgggcatcaa
     9781 cgaacaggcc atcatcaaat acctggtcac ggcctactac tcggccgcgg tgctggtacc
     9841 ggacgcactc ggcgtcctgg agaacgtcga gatcggccgc tggcggtgac gctgccggca
     9901 cgccggccgt gtccccgccc gtccgggcgg gtacaccctc ggggtacgag cccagcggca
     9961 gcggaagcgc caccgtccgc tcattctccg aggcggtccc atgggtgagt ccctcacgaa
    10021 gtccaggagg gggacgacgc agcccgcccg cggcgggcag cgcggcgccg aaccccggcc
    10081 gtcggccggg gctccgcaaa ggcagggggg catcgggaca cagggggacg gcgggccgca
    10141 accggccgaa gggcacgagg cggtcatgct gctggagcgg gcccgggcgg aggtcgaccc
    10201 ggtgctgcgg gccgcgctcg gctcgctgcc cgcaccgatg cgccgggtcg cgctccacca
    10261 cttcggctgg gagcaggccg acggcacccc ggcggacggg ggctccggca aggcgatcag
    10321 gcccgcgctg gtcctcgccg cggcggccgc cctcggcggg cccgaggcgc gggcgggggc
    10381 ggctcgggcg gccgccgcgg tggagctggt gcacaacttc acgctgctgc acgacgacgt
    10441 gatggaccgg gacaccaccc gccgccaccg ccccaccgca tggaccgtgt tcggcgacgc
    10501 cgacgccatc ctcgccgggg acaccctgca ggcgctggcc ctgcggctgc tcgcccagga
    10561 tccgcacccg gcgtcctcgg ccgccgccgc ccggctcgcg gactgcgtgg tggaactgtg
    10621 cgcgggccag cacgcggaca cggccatgga gcggtgcgcc ccaggcgagg tcacgctcga
    10681 cgaggtgctc gccatggcgg aggccaagac gggtgccctg atcgggagtg cgtgcgcgat
    10741 cggcgggctg tacgcgggtg cctcggacga ggaagtcgcg gcgctggacg cgttcggcag
    10801 ggaggccggg ctcgccttcc agctcatcga cgacgtcatc ggcatatggg gcgacccgcg
    10861 ccgcaccggc aagcccgccg gtgccgacct ggccgcccgg aagaaatcgc tgccggtggt
    10921 ggcggccttc gcctccggca caccggcggc ggccgaactt gccgagctgt acgcacgaac
    10981 cagcgagaag gaggacctgg accacatcgc cctgaccgtg gagcgtgcgg gcggccgtga
    11041 ctgggcgcaa ggccaggcgg ccgaccggat ggcccgggcg atgcagcagc tggcccgggc
    11101 ggtgccggac ccggaggcgg cgggcggcct gctcgccctc gccgagttcg tgacccggcg
    11161 cagcagttga cgggccgccc ggtggacggc cccaacagtg agcgctacgg cggcaaccgc
    11221 agaagaccgc ccgcaccagc aacgtccctt cgggtgaccg aagggcagga ctccggagcg
    11281 ccggggccgt gcggctcctg accccgcacg gccgtcggca tccggtcggc gggtcccgca
    11341 ctgccccacg gtctgcgggg cccgccacct cgccacatcc gtcgagtttg ggcacacgtt
    11401 cgatcggatc gcgccaagat cctgcccgca cccctccgtg agggccaacg cccctacgat
    11461 caacgcccgt cgggacgagc gaaggggtgc ggcatgggtg tggccatccg gacggcgggc
    11521 gcagaggaca gggagctgat cgtccggctt ctggacgagg cgttccagga cgacccggtg
    11581 agcggctggg tcttcccccg cgtggaggac cgccgtgcca agcacccccg gctcatggca
    11641 gccttcaccg acatcgtgct cgcggccggc cgcatagacg tcaccgagga cggctcggcc
    11701 tgcgcgctgt ggctctccat gcctgccgac gaaggccacg acgacgcgga ggacgagggt
    11761 ccggcccagg tgcgggaggc cgtcgacccg ggcaacgagc gtgtggagag catcggccgg
    11821 ctggtggccg ccgtccatcc cacggggcgg gcccacgagt acctgtggat gatcggtgtg
    11881 gcccccggcc gccaggacga gggcatcggc accgcgctca tcgaggccgt cctcgaccgc
    11941 tgcgaccgtg aagggctgcc cgcctacctg gaggccagca acgtccgtag ccgcaacctg
    12001 tacgagcgcc tgggattcga gccggccggc ccggccctca acctgccgga cggtccgtcg
    12061 atgtggccga tgtggcggga gcccaggcct cagcggcccg cctaggccgt atggcgcgtg
    12121 cggcagctgc cgtgcgccga cgagcagccg tttcgtccgg tgtctcctcc cgggcggacg
    12181 acgcgacctc gcggacgctc cgcctacgtc tcggcggtcc cgctctccgg gccggccacg
    12241 tgtaggaggc cgacggcacg ggacgccggg tggcttccgg acgtagctcc aacagggccg
    12301 gagaaaaaga gggtcggacc ggcttgcgga agcttgggca ggtcgtcgac gccgaaagcc
    12361 cggcgggcct gggtgggcag ggtcttcggg tattccgcct tgaggtaggc gatgactcgt
    12421 cgtcggcgaa acgcgatatc gcggtcccgt tgccgcccgg gtcaccgatg aagccgtcga
    12481 ggggacaggc gatgagttcg ccctggagtc ggtgcgcacg ttcggcaacg gcgcgctggt
    12541 gcgcacgtac agcaggaagc gttgagccca cgaccggcct actctgagga catgggcagc
    12601 gaaggatacg tctgtcccga ctgcggacag ccagtggaaa cggtcgtccg gcgtcataag
    12661 acgctgggca cctgggtccc gcgctgggtg gcgggcccgt gccgcaaccc cgagtgcggg
    12721 gcctgcgaga cgcagggcgc cgacagcggc cgcaccgccc aaggcacccg gcccgggcct
    12781 gcccccgcgg tccccggcga taccgccccg cccgccacga ccccgctcga accggcttcc
    12841 ggagacaccg ccgccaaaaa tccctgagcc cgtgtcgaga tgcgcggccc ggctccgacg
    12901 tcccctgtga agagccgccc gccggggcgg tgagagccga aggagcggac tgatgaagta
    12961 cctggtcatg gtgcagggca cacaggcgga ctacgacgcc atgcgcggca aggcgtcggc
    13021 gcactccccg gcctggagcg aggaggagct gcagacgatg ttcgcctaca tgggcgccat
    13081 caacgacgat ctggccgaga cgggcgagct cgtcgacggg cagggcctgg ccgagccggc
    13141 gcagacccgg cacgtcaccc tcggcgacga cggcaaggcc gtgatcaccg acggcccgta
    13201 cagcgagacc aaggagctgc tggccggcta ctgggtcctg gagtgcgaaa gtctggagcg
    13261 ggtcacggag atcgccgacc gtgtcgcccg ctgcccccag ccggccggcg cccccgacta
    13321 ccccgtcgtg atccgcccga tcatggacgg ttccggggac atctgacgaa ccggccgacg
    13381 ccgacggaca cacggggtca cacgggtgag gaacccaccg gagatcgagg acctgctgcg
    13441 ccgcgacgcg ccgcaggtcc tcggtgcgct ggtcagacgg tacgggcact tcgacgccgc
    13501 cgaggacgcc gtacaggagg cgctgctcgc ggcggccggg cagtggcctg aagcgggggt
    13561 gcccggcaat ccgcgcggct ggctgatcaa ggtcgcctcg cggcggctca ccgacgcact
    13621 gcgcagtgat caggcccggc ggcagcgcga ggagcgggcg gcagcgctca cgccccggga
    13681 cgccttcacg gcgccgccac cgggggagcg ggcgccccgt gaggacgaca cgctctcgct
    13741 gctgttcctg tgctgccatc cggacctgtc gccgtccgcg cagatcgcgc tcacgctacg
    13801 tgtcgtgggt ggtctgacca cggcggagat cgcgcgggcc tgcctggtcc cggagtcgac
    13861 gatggcccag cgcgtcagcc gggccaagca gaaggtgcgg ggcgtgcgct tcggccggcc
    13921 ggaccgctgg gagcagcggc tgccgtccgt cctgcagacc ctctacctga tcttcaacga
    13981 gggctacacc gccacgtccg gcgccgcgct ccagcgccgc gacctcgcag gggaggccgt
    14041 acggctgacc cgcgcggtcc accggctgtt gcccggcgac tgcgaggtgg ccggtctgct
    14101 cgcgctgatg ctgctgaccg atgcccggcg cgacgcgcgc ggcggaccgc gcggcgagct
    14161 gatccccctc gacgagcagg accgcggccg ctgggaccgg gcggcgatcg aggagggcgt
    14221 cgcactggtc acccgggccc tgtcccgggg ccgccccggg ccgttccagc tgcgggccgc
    14281 gatcgccgcc gtgcacgacg aggcgccctc gcccgggtcg accgactggg ccgagatcct
    14341 gggcctgtac gacgtcctcg tcggtctgct ccccggcccg gtcgaacgcc tcaaccgcgc
    14401 ggtcgccgtc gccatggtcc acggcccgcg cgcggggctg accgaagtgg acgccttgga
    14461 gggggagttg aaggggcacc gtctggacgc cgtgcgcggc catctgctgg agcgggtggg
    14521 cgagccggaa gccgcccgcg ccgcctacga gtcggccgcc gcacagaccc tgagcctgcc
    14581 cgagcagcgc tacctccggg cccgggcggc gcggttgagc gactagcgtg tgaagcatgg
    14641 gcattccggg ggagcggcgt cgcacggtgt ggcccggcgt ggtgatcggg tgggcgctga
    14701 tcgtggccgt cacgggcggc ctgacgctgt ggatgcagga ctcggccgag cccgcggggc
    14761 cgtacgtctg ggagcggacg aatccctacg agcccccgga cctgccgcct tgcccgacgc
    14821 ccgagggcgc cggggccgcg gactgcgcgt acgggacgta taccaagcgg ggctgacgga
    14881 tcgccccgca cacgcgcgcc gccacggacg caccgaacgc cgccccttct tcaacggacg
    14941 tccgtcagcg ttcctggccg cgcagtccgc ccgtcaccgg atcccgggtc gtcaggcagt
    15001 acgtgccgcc cgccggatcg cgcatcaccg tccagccgga aaagccggac acgaagacgg
    15061 ccccgagcgc ctcgtgccgc gcccgggtcg ccgcgacgtc agcgcaggcg aggtcgaggt
    15121 gggcggatgc cgggcgttcc tcgccgaggc gttgcaggag cagacggacc ggcaggcccg
    15181 gcggcggctt gaccacgtga aactccggga gagcgcccgg cagcgactcc cagccgtcga
    15241 gcagggcgct ccagaagccg acctccctgt cgtaggccga ggacgggacg tccaggcaca
    15301 cctggtcgag ccggctgccc cgcaccacgc ccgggcgcga cgactgcccg cgccaggggt
    15361 ccgcgcagaa caactgcccg ccgggcgagc gcagcaccac gagcgacccg aggtcggcca
    15421 ccacatccgc gccgcgccgc accgccgcgg cggcgaactc cggtacgtcg tcgacgcaga
    15481 agtcgatgtg cgcgccgccc gggcccggac ccaccgcctg caccttcacg cacgcgtcgg
    15541 cgccgtcgga cgtggggagc agggtcacga actcgtcgtg ttcaccgcgc ggtgcggaca
    15601 ggcgggtgtc cgtgaccgcc gtccagaagt cgcaggcggt gccgaaggcg tcacgcgggc
    15661 ggtcgatgaa ggcgtacgtc cagctgatcc tcatgggcgc gatcgtagac gggcgcaccg
    15721 ccgccacctg cgtgaacctt gaccagcctt tgccgtaccg ttccccgtgc attggcccgc
    15781 gcttgtttgc attcaggaat ggaccacatc acgttcctcg tggcggtcgt catcgtcacc
    15841 gcactcgcct tcgacttcac caacggtttc cacgacacgg cgaacgcgat ggccacgtcc
    15901 atcgccaccg gcgcgctcgc tccccgtacg gcggtcctga tcagcggcgt cctcaacgtc
    15961 gtcggtgcct ttctgtccac cgaggtcgcc aggaccatct ccggcggcat cgtggacgac
    16021 accctcgtct ccccgggcat gatcttcgcg gggctggtcg gcgcgatcct gtggaacctg
    16081 ctgacctggc tggtcggtct cccgtcgagc tcctcgcacg cactgttcgg cgggctgatc
    16141 ggggccgtgt gggtcggggc gggcagccac ggcgtccact tcggcaaggt cgtcgagaag
    16201 gtgctggtgc cggcggtggc ctcacctgtc gtggccggtg tcgcagcgct gctcgccacc
    16261 tacctcgcct accggctcac cgaccgggcc ggcaaggact ccgtcacccg gggcttccgc
    16321 atcggccagg tcgcctccgc ctcgctcgtc tcgctcgccc acggcacgaa cgacgcgcag
    16381 aagaccatgg gcgtcatcac cctcaccctg atctcggccg gcgcgctcgg ccacgacgcc
    16441 ggcccgcccc tgtgggtcat cgcgtccgcg ggcctcgcca tcggcctcgg cacgtatctc
    16501 gggggctggc ggatcatccg cacgatgggc aggggcctca ccgagatcca gtcgccgcag
    16561 gggttcgccg ccgaaaccgc ttcgacgacc gtcatcctga cctccgccca cctcggattc
    16621 gccctgtcca ccacgcaggt ggcctccggg agcatcctcg gcgcggggct cggccgccgg
    16681 ctcgcggagg tccgctgggg cgtcgcgggc cggatggccg tcgcctgggt gatcaccctg
    16741 cccgccgccg cactggtcgg ggggctggcc gccgcagtcg tgcagaacgg cggggacctc
    16801 ggcactgcgg tcgtcgcgat ggtcggcgcg gccctcgccg cgggcatcgt ggtcatctcg
    16861 cgccgcaacc cggtgcacgc gcacaacgtc aacgacgcac acgaagtcag catccgcacc
    16921 gagccgccgg ccaaggtcgg cgcggccgcc tgagcgacgg ggatcgacat gcatctggac
    16981 tggaccgcac tcggccaggt cgccgcggtg agtgtcggcg cgaccgtcgc cgtggtcgtc
    17041 gtcttcgccc tgggcgtcct cggcctcgcc cgcctggagg gcacccgcgc cctgcggggc
    17101 ggcaccttcg ccctcggcct cacccaggcc gtcctgtgct tcctcgcctg cgcggccgtg
    17161 gtggcgtacg ggatctacct gatcgtccct cagctccact agcagacgac gcccatgacg
    17221 aaggggcccg accggttctc ggtcgggccc cttcgccgta cgaaggcgat caggccttct
    17281 tggtctccca gaagatcttg tcgatctggg cgatgtagtc cagagccttc tggccggtgg
    17341 ccgggtcggt cgagcccttg gcggccgaga gggccttcag ggtgtcgttg accagctggt
    17401 gcagctccgg gtacttctcg aagtgcgggg gcttgaagta gtcgctccag agcaccgaga
    17461 cgtggtgctt ggcgagctcg gcgcgctgct ccttgatgac ggtggcgcgc gcctggaagt
    17521 gcgggtcgtc gttggcggcc atcttctcct gcacggcctt caccgactcc gcctcgatgc
    17581 gggcctgggc ggggtcgtac acaccgcagg gaaggtcgca gtgagcactg accttgacct
    17641 tgggggcaaa caggcgggaa agcatggagc attccttcct cgtgatcgtc ttctcacagg
    17701 ggacattact ccgtgaggga cggcttttcg cgggtgcccc catgggctta ggacaaaagt
    17761 ccggggtgag actgagactg gtggaggaag aaccggggag gtgccgggtg atgccggagc
    17821 tgtcgcagga gtccgagcgg gggaggcccg ccccgccctt cggggtggcc gaggtgaccg
    17881 ggccgtccat ggtgcccacg ctgtaccacg gggaccggct cctggtgcac tacgggggcc
    17941 gggtcaggcc cggggacgtc gtcgtcctgc ggcatccctt ccagcaggac ctgctggtcg
    18001 tcaagcgggt ggcccaacgg cgcgagagcg gctggtgggt gctcggggac aacgcgtacg
    18061 ccggcggcga cagcaccgac tacggcgtcg tccccgacga cctggtgctg gggcgggtcc
    18121 ggttccgcta ccggccgcgc gggtccggcc ggaggtcgcc ctgggcgctg ctgggctggg
    18181 cgctgtcggc cgccaggccg gtcctctccg accggtcggc ctccaggcgt ttgcgggcgc
    18241 ggtaggccgc cacgttggcc cgcgtcgcgc agcggtcgga gcagtagcgc cgggaacggt
    18301 tggtggaggt gtcgaggtag gcgttgcggc agggtgcggc ctcgcacagg ccgaggcggt
    18361 ccacgccgta ctcggtcagg tggaacgcca ggcccatcgc cgcgatcgcc gcgtagcccg
    18421 ccgtggcgtt cgacgggtgg tccgccaggt gcatgtgcca cagggggcgg ccgtcgtcgt
    18481 cccggacgtc gtgcccggag acctgcgggc tcaccgggaa ctccagcagc agcgagttca
    18541 gcaggtcgac ggcgagcctc tcctcgcccg cgtcggccgc ctcgaagacc gcgcgcagcc
    18601 gggcccggac cgagcggaag cgggtcacgt ccgcgtcggt ggcacggcgg gccgccgact
    18661 ggctgggccc gaacagatcg cggacggcct cgaccgacgt cagggcgtcc ttgccccggg
    18721 ccggttcctc ggtgttgacg aggcgcacgg catagtccga gtaataggcc agttccactt
    18781 gtagtcctta cggaggggct ttagggtcgt gagcgcgcac ttgtaacagc tgatggtgct
    18841 tccagggtat tacgaggaag gggctcgatg acggacgcgg acatcacgac gaccaccgcc
    18901 gactggcagg cctggcagga gagctgggac cggcagcagg agtggtacct gcccgaccgc
    18961 gaggagcggt tgcggatcat gctcgacatg gtcgaggcca ccgtgggcac cgccccgcgt
    19021 gtcctcgacc tcgcctgcgg cacgggcacc atcacggccc ggctgctggc ccgcttcccc
    19081 gacgccacca gcaccggcgt cgacctcgac ccggcgctcc tcgccatcgc cgagggcacc
    19141 ttcgcgagtg acgaccgggt caccctggtc accgccgacc tgaaggaccc cgactggccg
    19201 gcgcggctgc cgcacgactc gtacgacgcc gtcctgaccg cgacggccct gcactggctg
    19261 caccgggaac ccctcgcgga cctctacggc caggtcgcgg gactcgtccg cgccggcggt
    19321 gtcttcatga acgcggacca catgatcgac gagtcgacgc cgcggatcaa cgccgccgag
    19381 cgggcccagc gccacgcccg catggaacag gccagggaat ccggtgtcct cggctggacg
    19441 gagtggtggc agctcgcagc caaggacccg gtcctcgccg gacccacggc ccggcgctac
    19501 gagatctacg gcgaccacgc cgacggcgac atgccgtcgg tccagtggca cgcgcgcatg
    19561 ctgcgcgaga agggcttcgg cgaggccagg ccggtgtggt gctcgccctc ggacaccctg
    19621 ctgctggcca tgaggtagag cgggcgcaga ggaacgaagg ggcggtacgg agattccgta
    19681 ccgccccctc gccgtgcgta ccgtcagagc accttggaca ggaacgactt cgtccgctcg
    19741 tgctgcgggt tcgtgagcac ctcgcgcggg tggccggatt cgaccaccac gccgccgtcc
    19801 atgaagacca ggctgtcgcc cacctcccgg gcgaagccca tctcgtgcgt gacgacgatc
    19861 atcgtcatgc cggactcggc caggtcgcgc atgacgtcga ggacgtcacc gaccagctcc
    19921 gggtcgagcg ccgaggtcgg ctcgtcgaac agcatcagct tcgggtccat ggccagggcc
    19981 cgggcgatgg cgacgcgctg ctgctggccg ccggagagct gcgaggggta gttgcccgcc
    20041 ttgtcggcca gccccacccg gtccaggagc tcctgggcgc gcgtgcgggc ctggctccgg
    20101 ctcacgccct tgacctggac cggcgcctcc atgacgttct ccacggccgt catgtgcggg
    20161 aacaggttga agcgctggaa gaccatgccg atgtcccggc gcttgaccgc gacctcgctg
    20221 tccttcagct cgtagagctt gtcgcccttc tggcggtagc cgaccagctc accgtccacg
    20281 tacaggcggc cggcgttgat cttctccagg tggttgatgc accgcaggaa ggtcgacttg
    20341 ccggagccgg aggggccgat gaggcagaac acctcgccgg acttcacctc caggtcgatg
    20401 cccttgagga cctctacggg accgaaggac ttgtgaacgc cctcggcctt gaccatggcg
    20461 gtcatgcggt gcctcccgtc gacgccgagc ggttggacag ggacagcaga ttcgccttga
    20521 tcttctggaa cggcgtggcc ggcagggacc ggctggaacc acgcgcgtag taccgctcca
    20581 ggtagtactg gccgacgctg aagaccgagg tcagcagcag gtaccaggcc gccgccagga
    20641 acagcatctc ggcgggcgcg ccggaggtct ggccgatgtc ctgggccgct cgcagcaact
    20701 ctgggtactg gacgaccgag accagcgagg tcgtcttcag catgttgatg acctcgttgc
    20761 ccgtcggcgg cacgatcacg cgcatcgcct gcgggatgac gatccggcgc agcgtcttgg
    20821 cgtggctcat gcccagcgcg tgcgacgcct cggtctggcc ctcgtcgacc gagagcagac
    20881 cggcacggca gatctccgcc atgtacgcgg cctcgttgag cccgaggccc agcagcgccg
    20941 tcaggaacgg ggtcatgaag tccgaccact cgtccttgta gaacggcccg aggttgatgt
    21001 actcgaagac caggcccagg ttgaaccaga cgatcagctg caccaggacc ggggtgccgc
    21061 ggaagaacca gatgtagaac cacgcgatcg acgaggtcac cgggttcttc gacaggcgca
    21121 tcacggcgag catgacgccg ccgacgatgc cgatcagcat ggacagcacg
//
