LOCUS       NZ_CP015098            33260 bp    DNA     linear   CON 03-MAR-2024
DEFINITION  Streptomyces qaidamensis strain S10 chromosome, complete genome.
ACCESSION   NZ_CP015098
VERSION     NZ_CP015098.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces qaidamensis
  ORGANISM  Streptomyces qaidamensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
REFERENCE   1  (bases 1 to 9083372)
  AUTHORS   Zhang,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-APR-2016) State Key Laboratory of Cryospheric
            Sciences, Chinese Academy of Sciences, Donggang West Road 320,
            Lanzhou, Gansu 730000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 278x
            Sequencing Technology :: Illumina HiSeq 4000; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 10:55:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,226
            CDSs (total)                      :: 8,137
            Genes (coding)                    :: 7,871
            CDSs (with protein)               :: 7,871
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 266
            CDSs (without protein)            :: 266
            Pseudo Genes (ambiguous residues) :: 0 of 266
            Pseudo Genes (frameshifted)       :: 119 of 266
            Pseudo Genes (incomplete)         :: 213 of 266
            Pseudo Genes (internal stop)      :: 25 of 266
            Pseudo Genes (multiple problems)  :: 80 of 266
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:26:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3907796
            Orig. end                         :: 3941056
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP015098.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..33260
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="11"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..33260
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..33260
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:23260](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..23260
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            48..521
                     /locus_tag="A4E84_RS17090"
                     /old_locus_tag="A4E84_17090"
     CDS             48..521
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4E84_RS17090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4E84_17090"
                     /product="hypothetical protein"
                     /protein_id="WP_062927415.1"
                     /transl_table=11
                     /translation="MISTTFLPFIGVVLGGLVSTLTQYSLGRASERAEVRRSSRERAEA
                     RRNERVAHLVDFLSAVQEAERVAVDRHHHRLADEQWEARAKQSIDRMWVAQKTIHMLCA
                     SEVNEAARRLAYDVQDVIRKGPDDPEEPQDEKVWACIRPSRRAFLDVVRGHLE"
     gene            921..1253
                     /locus_tag="A4E84_RS17095"
                     /old_locus_tag="A4E84_17095"
     CDS             921..1253
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4E84_RS17095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4E84_17095"
                     /product="hypothetical protein"
                     /protein_id="WP_062927416.1"
                     /transl_table=11
                     /translation="MIRITKRCSAAVVLGSAVLATLAWAAPAQAAGQQGTGPAVAAQGE
                     IPVGVVLPHLPGSPDDFTWTPLPLGGDDFTWNPGPLHSGDDFSWHRSPAQGPDDFTWQP
                     GPVGER"
     gene            complement(1273..2256)
                     /locus_tag="A4E84_RS17100"
                     /old_locus_tag="A4E84_17100"
     CDS             complement(1273..2256)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010035526.1"
                     /locus_tag="A4E84_RS17100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17100"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_062927417.1"
                     /transl_table=11
                     /translation="MDDVSPLDQQTLAVYRAILFHKQHDPDKLAELLDIGRDDVHMALT
                     RLSDLSLLAPSGDSPGTLRAVNPSLGLKVLLQREQDELAWRQQRIEQNRAALAALAAEY
                     TASAGSGSDGTEQLDNVDEIRIRLEALAESCQQESLVFHPVGGLTKEAIEASRPLNERA
                     LARGVRFRSIYLDSAVSDRVTRAHAQWMAEHNSEVRTSPTLPMRLLIVDTTAAIVANLP
                     GQTGPAALMFHSRPVVLAMRALFEAYWEHATPFHQQSPDEDPQGLTPQERKLLQLLATG
                     LTDEAVARALGIGVRTERRIMAELMERLGASSRFEAGVQAARRQWI"
     gene            2417..2935
                     /locus_tag="A4E84_RS17105"
                     /old_locus_tag="A4E84_17105"
     CDS             2417..2935
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010035527.1"
                     /locus_tag="A4E84_RS17105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17105"
                     /product="hypothetical protein"
                     /protein_id="WP_237304939.1"
                     /transl_table=11
                     /translation="MSHTVAHVLPPLHGCVVLVVDATTGVGRRVTSQLCALGAAVAVVG
                     AGHPGRDDDAATNAAFLCKELAGIGLVALPYQADVERPESFRALTGQIAADLGQVTASV
                     VVVPSASGGEGPVQAFRVASGVVAASLPAGAEHIEVDVSGQGFSLEEAAQSVVERLVRL
                     HEQWRTPSG"
     gene            2998..3603
                     /locus_tag="A4E84_RS17110"
                     /old_locus_tag="A4E84_17110"
     CDS             2998..3603
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005310744.1"
                     /locus_tag="A4E84_RS17110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17110"
                     /product="response regulator transcription factor"
                     /protein_id="WP_062927419.1"
                     /transl_table=11
                     /translation="MSIRIVLAGDHQLVLEAFAETLNGVDGLEVVGLATSYDSVQPAVE
                     RHRPTVLLLGESTMGGKALRVATDVRSRHPRCGVALMVGAATASVVDRAVAAGALGVVP
                     KNARLPQLVTTLMGVAGGCLTVDPSLLRPVAVGELSLSTREMDVLRLTAGGATVKEIAG
                     ELYLAAGTVRNLTSAAIKKLGGRNRFDAARIAGEHGLL"
     gene            complement(3843..4958)
                     /locus_tag="A4E84_RS17115"
                     /old_locus_tag="A4E84_17115"
     CDS             complement(3843..4958)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036309.1"
                     /locus_tag="A4E84_RS17115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17115"
                     /product="3-dehydroquinate synthase II"
                     /protein_id="WP_031104993.1"
                     /transl_table=11
                     /translation="MTDAKLCWLDIRGAGTATQAVLEEALHQRIDGIVAADPAAFAGLP
                     PTVRKVLLFEDGLDAVPADLGAADLVVVPGPREERAALQEAHPDVEFGRYVEIVDADTL
                     EDACLAARLEPWSVLDFRDPTKIPLEIVIAAATGAPGSIITTASNTEEAEIIYGVLELG
                     SDGVLMRANTVGDATALRTAASARGGEIDLVELTVTRTTHIGMGERACVDTTTHFRKDE
                     GILVGSHSKGMVLCVSETHPLPYMPTRPFRVNAGALHSYTVSQAGRTHYLSELHAGSKV
                     LAVDVKGRTRPVSVGRVKIETRPLISIDAVAPSGQTVNLILQDDWHVRVLGPNAAVLNS
                     TELKPGDTILGHLPTADRHVGYPIDEFCLEK"
     gene            complement(4930..5910)
                     /locus_tag="A4E84_RS17120"
                     /old_locus_tag="A4E84_17120"
     CDS             complement(4930..5910)
                     /GO_function="GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010035530.1"
                     /locus_tag="A4E84_RS17120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17120"
                     /product="2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate
                     synthase"
                     /protein_id="WP_062927420.1"
                     /transl_table=11
                     /translation="MTAFGHFARSLRLRRLYRHSTAGLMITPLDHSISDGPVAPKGTSL
                     DHLAGQLAAGGADAVVVHKGSVRHISPERFAAMSLIIHLNASTSQALDPDAKYVVTQVE
                     EALRLGADAVSVHVNVGSDDERQQIGDLGRIADACDRWNLPLLAMVYPRGPRVTDPRDP
                     DLVAHAVTVASDLGADLVKTVFLGSTAEMLDLTAACPVPVLVAGGPAMPTEEDVLAYVR
                     DALAGGAGGVAMGRNIFQASDPRRLAAKVARLIHHFPEQHFAPLAFPADAHRAERLTPD
                     HLDAPAHPGAPGSPLDHDTHHLSDPSYSSHPTGGPHHDGRKTVLA"
     gene            complement(5907..8234)
                     /locus_tag="A4E84_RS45330"
     CDS             complement(5907..8234)
                     /NRPS_PKS="Domain: AMP-binding (18-415). E-value: 1.2e-69.
                     Score: 226.8. Matches aSDomain:
                     nrpspksdomains_A4E84_RS45330_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="A4E84_RS45330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AMP-binding protein"
                     /protein_id="WP_063827501.1"
                     /sec_met_domain="AMP-binding (E-value: 3.5e-72, bitscore:
                     242.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTEAIPRPYARRVLAALGRDPTRIVLHRPERTVTAGELHASVLG
                     SAALLHSHGVRPGTTVAILTGPNHPLMLSARWAVHLLGATSVYVRSMNPRTDTETFSVA
                     TQTGLLRDLGVSLLLVDDTDEESASRGRWLARRRPGLTVRAIPRTADGHDTVPPAPPPH
                     PGDLAVVDFTSGSTGRPKMVAQRYGTREHLVGRLASGLDPRGPATLLSVTPVSHTTAPM
                     ADAVLCSGGTVVLHDEFDAGATLTAIAELGVTDVYVAVPHLYRLLDHPLVTSYDLSSLR
                     RITYSGTPAAPERVRQAVRVFGDVLIQVYGTTEAGGISSLTPLDHREPELLGSAGRPFP
                     WVRVEIRAAGSGTPLGRGRTGEIWVNSPTVSAGYLDDAELTEATYRDGWLRTGDLGHWD
                     HYGYLRLDGRVGDVIKHGGLKLDPAAIEAALLRHPQVRQAAVFGVHDEDLVEQVHAAVE
                     LHSGAGHTSCDLRGYVAATLTPEHAPVSVSVWPELPLTPSGKPDRARLRGVTTPVRARP
                     TGDAPPKRVTGSSAGPGSATGRVSDTGPVSRMGPVSGTGPGSATGPGFVAGRVSATGPV
                     SDTGPVSTMGPVSGTGPVSATGSVSTMGPVSGTGPVSGTGRVSARGPGSATGPGFVAGR
                     VSVTGSVSDTGSAATEPIPPAVDHPAGHPPAVGPPARHPLAEGPPPTRPGEGVPSMRPA
                     DGSPPTRQADGLPSMRPADGSPPTRQADGLPPTRPAGAPAPPPAERRGTGPPDPGGTAG
                     PDARRTTDRRTRTDPRNRKGIP"
     aSDomain        complement(6990..8180)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_A4E84_RS45330_AMP-binding.1"
                     /evalue="1.20E-69"
                     /label="A4E84_RS45330_AMP-binding.1"
                     /locus_tag="A4E84_RS45330"
                     /protein_end="415"
                     /protein_start="18"
                     /score="226.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="GRDPTRIVLHRPERTVTAGELHASVLGSAALLHSHGVRPGTTVAI
                     LTGPNHPLMLSARWAVHLLGATSVYVRSMNPRTDTETFSVATQTGLLRDLGVSLLLVDD
                     TDEESASRGRWLARRRPGLTVRAIPRTADGHDTVPPAPPPHPGDLAVVDFTSGSTGRPK
                     MVAQRYGTREHLVGRLASGLDPRGPATLLSVTPVSHTTAPMADAVLCSGGTVVLHDEFD
                     AGATLTAIAELGVTDVYVAVPHLYRLLDHPLVTSYDLSSLRRITYSGTPAAPERVRQAV
                     RVFGDVLIQVYGTTEAGGISSLTPLDHREPELLGSAGRPFPWVRVEIRAAGSGTPLGRG
                     RTGEIWVNSPTVSAGYLDDAELTEATYRDGWLRTGDLGHWDHYGYLRLDGRVGDVIK"
     CDS_motif       complement(7086..7163)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4E84_RS45330_0002"
                     /evalue="3.00E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="A4E84_RS45330"
                     /protein_end="383"
                     /protein_start="357"
                     /score="22.8"
                     /tool="antismash"
                     /translation="GRTGEIWVNSPTVSAGYLDDAELTEA"
     CDS_motif       complement(7683..7730)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_A4E84_RS45330_0001"
                     /evalue="7.80E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="A4E84_RS45330"
                     /protein_end="184"
                     /protein_start="168"
                     /score="15.5"
                     /tool="antismash"
                     /translation="VVDFTSGSTGRPKMVA"
     gene            complement(8272..9759)
                     /locus_tag="A4E84_RS17130"
                     /old_locus_tag="A4E84_17130"
     CDS             complement(8272..9759)
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010035534.1"
                     /locus_tag="A4E84_RS17130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17130"
                     /product="multicopper oxidase domain-containing protein"
                     /protein_id="WP_062927421.1"
                     /transl_table=11
                     /translation="MFSRRHAIRLGLTTGAVGAVGAAGGVFRTLTAAGQGTAAGKAAPA
                     GAAAAPVEPFSLPLTIPPVLAPYRRTKTADHYRITMRRTGVEILPGTRTDALTYNGTFT
                     GPTIRARTGRTTVVQQINALDMPTSVHLHGGNNPVAHDGGMMDTIAPGRRRTYVYENKQ
                     PGATLWTHDHAHHMESEHVYRGLSGLYLLRDPAEDRLGLPSGKYDIPLVLRDAHFDDND
                     QLVYTMDDPENRTTILVNGRPWPRLKVEARKYRFRLVNSCNLRIFILALSDGSATQHPV
                     QQIGTDGGLLAAPAETPVLVLSPGERIDFVVDFSRYAPGTELTLANMLGPGPTELVGQV
                     MRFDVGERTADTSRVPATLATLPALAKPTVERSFDLSMDEPGSGGHQAYINGKTFDPDR
                     IDTHIEWGSTEVWTVTNKSATVPHNFHTHLVQFRILERDGQPPYPAETGWKDTVLLFPG
                     QTAKLQLTFDSHRGVYPYHCHMIDHSAMGMMAQMKIA"
     gene            10001..11578
                     /locus_tag="A4E84_RS17135"
                     /old_locus_tag="A4E84_17135"
     CDS             10001..11578
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: goadsporin_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010035536.1"
                     /locus_tag="A4E84_RS17135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17135"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_062927422.1"
                     /sec_met_domain="goadsporin_like (E-value: 1.7e-189,
                     bitscore: 629.5, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PF00881 (E-value: 9.5e-13, bitscore: 47.4,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPAGTKAITEKPPESAARALRGDVRVTFDDGTDTALLRGPVTSL
                     ALRPVRGPLRGVLLRLAEGPLPREELYEGLDAAGRKRADALLERAAQLLAYSVLTHDEP
                     PLRRELVRLEPTARDAVHRVADVAAGDRVRLSRFAFCRTRDGVLVLESPLVKFRAVLAD
                     RAARELAAALGQPGRAGSAGEVTGLSEAETLDVLSHLVGLGFAELAGPDGTFASDTEPV
                     LRQWDFHDLLFHSRIRSGRYDGVFGAVYPYRGEIDPEPAVKPAPPGPVTELYRPRRADL
                     DAADPSLTAAIESRRSHRAFGERALTARELGEFLYRVQRVRVHRTPGPDSPGEDEVVSR
                     PYPSGGSLYELELYATVVRCDGLEPGIYHYDSYAHRLVLVSSEEAARRALLGVASRSVG
                     FDVHPDVLFTVTSRFQRMAWKYRAMAYATTLRHTGVLYQTMYLVATAMGLAPCGLGNGD
                     ADLSARVLGLDYLRESSVGDFLLGTPAGGTEPPADPGEEWHMVNSPDWAIPLDGPGEPG
                     GGEKSLAP"
     gene            11744..11917
                     /locus_tag="A4E84_RS40810"
     CDS             11744..11917
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005310732.1"
                     /locus_tag="A4E84_RS40810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiazolylpeptide-type bacteriocin"
                     /protein_id="WP_078615318.1"
                     /transl_table=11
                     /translation="MTAKDIKNQDADKAFEGFDADELETLEVTDGVALPEMGASSGSIG
                     TSSSSSSTCSAC"
     gene            11952..12125
                     /locus_tag="A4E84_RS40815"
     CDS             11952..12125
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005310732.1"
                     /locus_tag="A4E84_RS40815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiazolylpeptide-type bacteriocin"
                     /protein_id="WP_079128999.1"
                     /transl_table=11
                     /translation="MTAKDIRNQDADKAFEGFDADELETLEVTDGVALPEMGASSGSIG
                     TSSSSSSTCSAC"
     gene            complement(12228..12824)
                     /locus_tag="A4E84_RS17140"
                     /old_locus_tag="A4E84_17140"
     CDS             complement(12228..12824)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015578242.1"
                     /locus_tag="A4E84_RS17140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17140"
                     /product="hypothetical protein"
                     /protein_id="WP_237304940.1"
                     /transl_table=11
                     /translation="MTSTSPTTPPTPSATDAECLALTRNLRRRGVLVLSLFALMWALAA
                     ASGTGSATDAVPLGIEAAALLLTASAIYLGYRRGAAPSPRMVNLPANWARGVGIVNTVE
                     LAAIFAVIAASNAAGRPEAIPAGIALVVGLHFFPLARLYDQWQYRWTASLLTAVAVAGF
                     VLVAAGLASETVRIVVGLGSALVLWASSYHLALRG"
     misc_feature    12941..12956
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.49"
                     /tool="antismash"
     misc_feature    complement(12995..13008)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.21"
                     /tool="antismash"
     misc_feature    complement(13033..13047)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.04"
                     /tool="antismash"
     gene            13131..14207
                     /locus_tag="A4E84_RS17145"
                     /old_locus_tag="A4E84_17145"
     CDS             13131..14207
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010035539.1"
                     /locus_tag="A4E84_RS17145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17145"
                     /product="hypothetical protein"
                     /protein_id="WP_174569434.1"
                     /transl_table=11
                     /translation="MPVTPAWLARHVVPVARGLGERGVPGVQVRRGWLHGPHVDVLAPA
                     GALPPGGAVDWAAIEAGWDAGPLDPARALTEEVYLDQAREFGRLEAVEPPYLPLREHGA
                     VLRVGPGDPALRSREPRLDALRTVVHGALAAPVLTMIEGLAEEPGSGTVRLAEAFAALV
                     DTHALGPAYGVFSPRSHVEAFLAWAAPRKDMRPVFRERLAKEAPRIREVVEQRLSGAVS
                     PAAAQWRTAFAYGAGVLDHAVATGALTPDLLDSVTDGVDRSRMGPPGAEAVVPRGEQPD
                     TDFHRTVHGSGAISTPSPFFAAYRLLTNLFYQQLPLLTVSPMQRYYMCFALAETVDDVL
                     GSSWRERLTATRPTGAPR"
     gene            14204..16816
                     /locus_tag="A4E84_RS17150"
                     /old_locus_tag="A4E84_17150"
     CDS             14204..16816
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_N"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036318.1"
                     /locus_tag="A4E84_RS17150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17150"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_062927424.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 4.5e-14, bitscore:
                     50.4, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPEPQWFLRVNPLRRTRLADPEQRRLLAELARAEAELAEVAEV
                     CSQELYERIGAAGSDAERRELIALRRAVHNGRAAKKTPESLEATPSVARWLAAWTGRER
                     LRTAVTQGYPAAADRERAVLAALLGDGDLLRSLALIAPEVHQEAERYRAAVEGPGKVSA
                     RTRKSERGLIQYVTRAMVRTSPLSRFTAVGIAEPAPAGDPDAVRPGEVPFTGAHAVPGL
                     DRVMLHYVLGGLPADDTDPSGLWVGMPPTSAPDPESGKLFFLKFSEQGMHRLAVPLDGP
                     VAHLLDALSMGPRRFPAVVEHVAARAGCSAEEAEGRVRQALHQGVLCTFTRPEEETAAG
                     DYDDLLTLPDVEQPPGVRELANRVRAGLPRVTEAPAAGRGALLAGLRGDLGRFSQAAGR
                     PAHITVEEDYVMPPLKVAASDWHAPLAGLGPAVELLTVFDWLHDVRVLMTAAFTERFGA
                     GANVPLAEHAAFIVGEVSRRAAAMAAVYGPGGTGQAAALSGIGPADGCLERMYLLRREL
                     SEEVHALLTKTAQAGEDTLRLTAADVAELTRALPDRFRSDPLIYGVLLQQAGDQLVLND
                     GLPGHGMLYARFLEADRRQGGRALPRLAEHLRRFYGHDGTRITEDLGLHRLNVNAHTPV
                     LPGGLTAEDWFTLRLAHDPETDTLRVEDADGAPLRVLPLGTGHPGLFPPPLSVASGLVI
                     SGRLFNSLPNSWHATTPWDGKHTRVAPRMAVGDVLIGRRRWYGGAELDTAVAAGPDEHE
                     RLLALTAWRSRHGVPEEVVIKSAPEDEGPLSVGAPDVQSKRLAQKPQYVDLSSALAVRV
                     LPRMLERRGAGTSYLEEALPGVTDGTHATEWVLEVGRTAGGHFEYHPADGGAVEGVRS"
     gene            16813..18867
                     /locus_tag="A4E84_RS17155"
                     /old_locus_tag="A4E84_17155"
     CDS             16813..18867
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4E84_RS17155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4E84_17155"
                     /product="hypothetical protein"
                     /protein_id="WP_062927425.1"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 8.6e-11,
                     bitscore: 40.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVTDVERTPARTASDAVPLMARPGLHYAPVPGGVYFSGTRGQFV
                     LRGSELLYAVADGCVPLLRAGTTEDALVAEFGTERARPAVRHLLGKLRENGLLLDPAAL
                     TEPEPPAELAARHAGTLARLTARLDDPYAAFARLRRARVRLHGPATATAPALRGLRRAG
                     VTDVTATAVPLTPTSLVPVCDPAMYADPALLSGRPGPAGDSGPLFPAGAPAAHHPPTPA
                     GDPAVNQPGTRTPVGDPTVDAPGTPTPVGDPAVHHPPTPAGDPATHHTGTRTPAGDPAA
                     HQPGTRTPVGDPAVAASVMGEGVPGVVVEFLDGDRTWTEGDGTLHVPVLLGPGPVLVGP
                     VGVAPGVWEVFRDRVRAWADAEGVEPATGPIAHSLAGALAAQLLTDTLTGVAEPGEAHV
                     VHGPDLTADRVTVTGAPVSEAVAVRLGDAPAEPFPAPEDALGAAGVLTARWTGLFASPQ
                     GEDLPQMPLALRAAEHRADRTGTVTAWAAHQETAVVAAALAALRDRGTRASGIPAAGLT
                     REHWLLDGALRHLARQDGDGRDADTPLHAEGRRILAEVRALLGEAEPVLAVTRYAGVGW
                     PLAEVTAAGRPLGRGWGPTAADATYAALCTALAVAQSGGTADRLSTDALLTADDTARAA
                     LREQLSAIAVHAGHPRRTDPVLGELPFWHGPVTVRAVPTTAEESGDADH"
     aSDomain        16873..17109
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_A4E84_RS17155_Thiopeptide_F_RRE.1"
                     /evalue="3.00E-13"
                     /identifier="RREFam004.1"
                     /label="A4E84_RS17155"
                     /locus_tag="A4E84_RS17155"
                     /protein_end="99"
                     /protein_start="20"
                     /score="40.6"
                     /tool="antismash"
                     /translation="MARPGLHYAPVPGGVYFSGTRGQFVLRGSELLYAVADGCVPLLRA
                     GTTEDALVAEFGTERARPAVRHLLGKLRENGLLL"
     gene            18854..20758
                     /locus_tag="A4E84_RS17160"
                     /old_locus_tag="A4E84_17160"
     CDS             18854..20758
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010035543.1"
                     /locus_tag="A4E84_RS17160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17160"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_062927426.1"
                     /sec_met_domain="YcaO (E-value: 5.6e-69, bitscore: 232.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 9.1e-70, bitscore:
                     234.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTTDAITAGPALPPTAYDDWLPALAPLARATGATVSVNLGWDLT
                     WERDRVTRAGGPHLSVRVYDDEVMVGPLWVPDTAVGCAACAEVRERTVLDHPLVGDLTQ
                     AMRVPAGPAPLLPELLRTGLDHLAAHPLAPGEAYSVTVRGTRRHRIARSFHCPACGPSR
                     EDLTTTEAPAPRPLPSRPAVPGDATRTAASRLVEPGFLRDRLVDDRFGPVRAILRESHA
                     PFAMSMAVVADAPAMGHGRARTFAETEPVAVLEAYERLGGYPYDIPLLTGRSYREVAGQ
                     AVDPGSLGRYTAEQLAHPTSRATPFTADTPMDWAWGHDLADGTPLLVPADHAFYQYEYA
                     FRRDRRAARVAGAANRRHYFFDCSSGCAVGANHEEAALHSLFELAERDAFLTSWYRAEP
                     LPHIPVGTLTDPTSRAMVELIRARGYDVHLLVATRDIGLPVVWVIAVNEKDPFPATFSS
                     AGSGAEPESAIRGALREVAQLVTNPVDWTREQVERMVEDPWLVEELEDHVRFSSIPETR
                     HRALAGLGGPAVTLEEAFPDWPGRLERASGGDVRGTLRYVASLFADAGLDRIVVVDQTS
                     REHADAGIAVARAVVPGIVPMCFGHAQQRLDGLPRLRAALRGTGQEHRAIPYDPHPFP"
     gene            20755..22299
                     /locus_tag="A4E84_RS45230"
                     /old_locus_tag="A4E84_17165"
     CDS             20755..22299
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010035545.1"
                     /locus_tag="A4E84_RS45230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17165"
                     /product="nitroreductase family protein"
                     /protein_id="WP_062927427.1"
                     /sec_met_domain="PF00881 (E-value: 2.8e-07, bitscore: 29.6,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPAEPWTRRAPVDLPGPEGDSSIAREPLWYAYGAGDDAPEPPP
                     WTWTATPPPDAHVPPPPPRPPGPATPLPPGTTDRLAALPYPWLPAPGPASPEALAHALT
                     ATFAPLRREPENPYNEHRSYASPRCLFPVHAFVGDGRDWRLLEPTRHTLTGPGTGTPGR
                     IALTGRYTAIPRAYQWFRGSLVAIETGLVLRALSLGLELFGLPATLTPPTADGPELLRE
                     LGVEHTWEWSLPWLVELDEPQGAGREVTGFKEPPVPGGDPSLTDVVRANRAQPHGPGGA
                     GNRATSHTQPAPVTTAVPPTLPDSPHAPTWSDLLWHRHSGRMPRALHGMDSAKCLTPLP
                     ARTLTTALAWLGVPPPHPLLAEAFDAVTVTAVVQHIDGHTPGIHRIHDGTADLLRRDPT
                     APAGLEANYGYGLTPVNGCGIANAPLTVFFSVRPRELFARFGPAGWSAAQHACGWAVHG
                     LCLAAAAEGLFARPVRAFKEIQTKEVLGLGEDETIVLSAVAGVPRETGGAVLDLRT"
     gene            22340..23260
                     /locus_tag="A4E84_RS17170"
                     /old_locus_tag="A4E84_17170"
     CDS             22340..23260
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010035547.1"
                     /locus_tag="A4E84_RS17170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17170"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_062927428.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2e-41, bitscore:
                     141.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTTPHDWSAWHLHLGTTARGAHDRVLTDVIGPTVAELPPATPWF
                     FIRYWQSGPHLRLRVADLSADAHAHVERALRDRLAEAGRLAPGEEPVAEEAYQQGASRL
                     AAAGETGANTTVRALLPPGVHRAGYDPEYERYGGSALMPAAESLFHLSSELVLRLAPLV
                     TSEARRARLALRGTLSAAVALGGPDERAHYFARGRDAWRAWARDAGHSAELLDRITTVV
                     QDPATAGVAPDAHGPFTGWHEALTAHAAEIRRHSPVHPGMILFSHAHMLHNRLGLSLLE
                     ELRTYAWLSHVFPVPAAAPGLAPTG"
     gene            complement(23559..24392)
                     /locus_tag="A4E84_RS17175"
                     /old_locus_tag="A4E84_17175"
     CDS             complement(23559..24392)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010035551.1"
                     /locus_tag="A4E84_RS17175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17175"
                     /product="ABC transporter permease"
                     /protein_id="WP_062927429.1"
                     /transl_table=11
                     /translation="MTSTLPPTTTATARRAERAGRERPDERGSLALLAHQIRYEQLSFW
                     RNPQSMVFTFVLPIVIISVFGAVFAGSESQDFFFGLSGLQYYTPAIAAVSVLGACYGQL
                     AIVLAMRRQTGVLKRLHATPLPAWVYFAGLLVHCVVVSVVDVALVIGIGRLYGVPWPAD
                     WAALALTLVLGAASFCALGVGVASLIRNSEAAPAVVQFIQFPLVFISGSYFPIHSDVMN
                     NIAGLLPVKPFNDAMLAPFAHQGGFQWKELAVLAAWGVVGALIAVRSFRWDPRPE"
     gene            complement(24389..25387)
                     /locus_tag="A4E84_RS17180"
                     /old_locus_tag="A4E84_17180"
     CDS             complement(24389..25387)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010035553.1"
                     /locus_tag="A4E84_RS17180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17180"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_062927430.1"
                     /transl_table=11
                     /translation="MTAVAVDGLLKRYGDHEAVRGVGFAVEEGEIFALLGPNGAGKTTT
                     MEILEGFRHRDGGDVRVLGRDPGDKADGRWLRGQIGLVLQDIAVEPYLSVRETIARNAG
                     YYPAPRGVDEVIDLVGLEEKRDAKVKDLSGGQKRRLDLALGVIGDPKLLFLDEPTTGFD
                     PGARRGAWEVVRSLRDAGTTILLTTHYMDEAQALADSVAVIAGGRIVAAGTPDTIGGRD
                     SALARIRFALPAGAAIDDVPIPVSDAEDGLVTAEAEEPTAALHRLTSWALDRGTPLERL
                     TVEQPTLEDVYLGLTSTYAEQDASSPSTGRGSTPALAASARRGRRPGRSRR"
     gene            25604..26932
                     /locus_tag="A4E84_RS17185"
                     /old_locus_tag="A4E84_17185"
     CDS             25604..26932
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036325.1"
                     /locus_tag="A4E84_RS17185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17185"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_237304941.1"
                     /transl_table=11
                     /translation="MTVRPRRPRHGGDGRDAKTRKAVPEVLLGEDTGGRRLPGNSAEPS
                     GGERPTVAVVGAGIGGLTLAGALGANGTPYVIHEQTRELAEVGAGVQLSPNAIRPLLRL
                     GLGPALREHGVRIEAMEVRGWNGRPIARTPLGADCERMFAAPYLTIHRAHLHDALLSLV
                     DRDRLGLGQRLSAAGERPDGTGVRLTFDDGSVREADVVVGADGIHSTVRETLRRDEPVY
                     SGLGIYRGLVPVDALPAEARERLVRLWLGPGGHFVAYPVASGTYLSYAATVPLPSDAPP
                     RESWSRPGDPDELRAVFGSWTGLVADIVAAVETTHQWALHDRPPLRTWSTDRITLLGDA
                     AHPMLPFMAQGANQAIEDAMDLAACLADAPAGAIADRLARYESLRIPRTAEVQRGSRGN
                     AGILHLPDGPAQRRRDAQMAVHAALRDRAALYAHETGRSVVPA"
     gene            <26964..>27077
                     /locus_tag="A4E84_RS42240"
                     /pseudo=""
     CDS             26964..>27077
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011028255.1"
                     /locus_tag="A4E84_RS42240"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="glycoside hydrolase family 11 protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MEGIRTFDQGGSVRQSKRTGATIAAGNHFEAWARAGMP"
     gene            27266..27619
                     /locus_tag="A4E84_RS17190"
                     /old_locus_tag="A4E84_17190"
     CDS             27266..27619
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A4E84_RS17190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="A4E84_17190"
                     /product="hypothetical protein"
                     /protein_id="WP_159029586.1"
                     /transl_table=11
                     /translation="MGHRGRRGRRRRGLALVLAVAGAAVLVRGTLRGAMDRRWWGVLGP
                     LVVLGLMVGVGWRILTAGGIGANIGAGLLIIFGTPVAAGLLLWALAWAFWLVTQRHGHE
                     GGGDLGGIASRGV"
     gene            27748..28551
                     /locus_tag="A4E84_RS17195"
                     /old_locus_tag="A4E84_17195"
     CDS             27748..28551
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010035562.1"
                     /locus_tag="A4E84_RS17195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17195"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_062927432.1"
                     /transl_table=11
                     /translation="MSDDSLRDRIDTSKPHSARFWNYFVGGKDNYEVDREIGDQIKSIF
                     PGLVDVAVTSRRFLGRAVEYLAGEQGVRQFLDVGTGLPTADNTHEVAQRVAPDSRIVYV
                     DNDPIVLAHANALLTSTPEGRTAYLDADLYDPEAVLKAAAGTLDLSRPVGLMILNTLGH
                     VADYERARELVRRLMAGLPAGSHLVISDSTATSEGMIAASEAYNASGAVPYHVRPVAEI
                     AGFFDGLELVEPGVVRVPEWRPRAFGDAGFGDGAVDAYCGVGRKP"
     gene            28675..29358
                     /locus_tag="A4E84_RS17200"
                     /old_locus_tag="A4E84_17200"
     CDS             28675..29358
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003990962.1"
                     /locus_tag="A4E84_RS17200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17200"
                     /product="hypothetical protein"
                     /protein_id="WP_062927433.1"
                     /transl_table=11
                     /translation="MPAPPSVPEPAGRLLGDLLAVGEAYSLVLAGGYAVLAHGLLERAG
                     PAVDAATEHPAAMEVVADTVRTGLVGRGWLVQTLETGPLSAQFLVTDAASGVECEVALH
                     KEVLWRPPVETELGPALSLHDLVGTRVRDLADRGLARDLVDVHAASARWSHPELEELGR
                     RHAPDTFDLTDLHARLTGTDWLDDRAFTVAGLDAPAVAGLRRWAQEWADDIAERLIEGE
                     APDEE"
     gene            29404..29889
                     /locus_tag="A4E84_RS17205"
                     /old_locus_tag="A4E84_17205"
     CDS             29404..29889
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003990963.1"
                     /locus_tag="A4E84_RS17205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17205"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_079129000.1"
                     /transl_table=11
                     /translation="MGNGAAGQVGVVAALVRAAFLVDGVYAEASRAYGLTPQQGQLLCV
                     LMSRPYGMSELGETLGLAKSGLTGLVDRTVRRGLVRREADPRDGRAVRVGLTDQGAALA
                     GKFYAETCRRMEALPSGLSGTERDRLARLLSRVVVDNEVPEVFVETATVSASGGSPS"
     gene            complement(29897..31075)
                     /locus_tag="A4E84_RS17210"
                     /old_locus_tag="A4E84_17210"
     CDS             complement(29897..31075)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003990964.1"
                     /locus_tag="A4E84_RS17210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17210"
                     /product="hypothetical protein"
                     /protein_id="WP_062927435.1"
                     /transl_table=11
                     /translation="MRSYRELFRTPEFTPFFLAASAQTVAQTMGGLALGTLVYRATGSP
                     LLSAVSMFGSSLVQVLGATLLLSAADRLPPRAALTALPLLFAAATAALALPAMPVWGLF
                     VVVLAKGLVESVGGGVRWGLLNEILSKDGYLLGRSVFNMMSGVMQIAGYAAGGALVALL
                     SPRLSLLAAAGLYGAAAVVVRLGLTRRPPRTTGRPSVAATWRANALLWSSPPRRQVYLA
                     LWIPNGLVVGCESLYVSYAPDSAGTLFACAALGMLAGDVLVGRVLPSGLRSRLGFPLLL
                     LLAAPYVVFLLRPALPLAAAAVALASVGFGASLVQQERLVALTPDGLTGHALGLHSAGM
                     LTMQGVAAALAGSVAQLTSPAVAMGAMAVASAGVTLLLMGAAKREEPRAVSR"
     gene            31155..32150
                     /locus_tag="A4E84_RS17215"
                     /old_locus_tag="A4E84_17215"
     CDS             31155..32150
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003990965.1"
                     /locus_tag="A4E84_RS17215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17215"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_062927436.1"
                     /transl_table=11
                     /translation="MGWWQISADTLAGSRFVISPFAEAFASLRLLHAADAAHPGERRWL
                     DAHLPAYRRRLARDPVTAQLIRAGIGREWTADFLSPAPRDGEPFEQEVARVRAADPEAA
                     RADLTVSLRGPVPAVLHRDDLPERAADLLTYVWTTAVRPYWSQRRHILEADVVARTARV
                     SRGGWASALDTLRPGTQWLGENRLQVNAHEYPPRELSGAELVLVPITTQRIGWVAWGGT
                     DRYALVYPCAGALADSGGRPAPASLGALLGTARAGVLVRLGSPLSTSQLVAVTGQGLGS
                     VGRHLRVLLDAGLVERRRAGRSVLYSRTAAGQVLVEATEARNSPELGSEA"
     gene            32147..32650
                     /locus_tag="A4E84_RS17220"
                     /old_locus_tag="A4E84_17220"
     CDS             32147..32650
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020121687.1"
                     /locus_tag="A4E84_RS17220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A4E84_17220"
                     /product="glutathione peroxidase"
                     /protein_id="WP_062927437.1"
                     /transl_table=11
                     /translation="MTTTNGSSPLDVEIGALQGGPADLSQYAGKAVLVVNVASKCGLTP
                     QYTGLEKLHEQYAARGFSVLGVPCNQFLGQEPGSADEIAEFCSATYGVTFPMTEKVDVN
                     GDDRHPLYDRLTGFADAEGHSGDIRWNFEKFLIGRDGRVVARFSPQTEPDSAEIVTAIE
                     AELA"
ORIGIN
        1 tatccggaag aaccgcgaca cctgccgtgc gggtgccaca gtgagccgtg atctcgacaa
       61 cgttcctgcc gttcatcggc gttgtgctcg gtggcctcgt atcgaccctg acccagtact
      121 cgttgggccg cgcttcggag cgggccgaag tgcggcggag ctctcgtgaa cgcgccgagg
      181 cgcgtcgcaa cgaacgcgtc gcccacctcg tcgacttcct gtccgcggtg caggaagccg
      241 aacgggtcgc cgtggaccgc caccaccacc gtctggccga cgagcagtgg gaagcgcggg
      301 ccaagcagtc catcgaccgg atgtgggtgg cgcagaagac gatccacatg ctgtgcgcgt
      361 ccgaggtgaa cgaggcggca cgtcgactgg cgtacgacgt ccaggacgtg atcagaaagg
      421 gccccgacga tccggaagag ccgcaggacg agaaggtctg ggcctgtatt cgccccagtc
      481 ggcgggcgtt cctcgatgtc gtgcggggcc acttggagta gccactggcg gagagtcccc
      541 gggcaccgtc agagcaggtc cctgagggca cgctccagcc gtgcaaccag ctgccaggtg
      601 ccccagtccc gcacacgccg gacgtctccg gcactggccc accagaagcc gggagaagcc
      661 gctcaccggc accaaccgca ccaccacacg ccacgacaca gcagccgtgg cgtgcccccc
      721 tcagggaccg gggtgcaact ccctgccagg cagcttcctg gcggggccgg atgcggacag
      781 gggcatcggc gggatggttg tctcttctca gcggccggga agcgcgggga acgcggaacg
      841 gtccggggga gctgaagcac caccggctcc atgcgcagcg tcgcgaaggt tctgactcac
      901 gcagggaacg gagaccagaa atgatccgca tcaccaagcg ttgttccgcc gccgtcgtcc
      961 tcggctcggc cgtgctcgcc accctcgcct gggcggcgcc cgctcaggcc gccgggcagc
     1021 agggcaccgg cccggccgtc gccgcacagg gcgagatccc ggtcggcgtc gtactgccgc
     1081 acctgccggg ctcgccggac gacttcacgt ggacgccgct gcccctgggc ggcgacgact
     1141 tcacctggaa cccggggccg ctgcacagcg gtgacgactt cagctggcac cgctcgccgg
     1201 cccagggtcc cgacgacttc acctggcagc ccggtccggt gggcgagcgg tgatcccgtc
     1261 ggtgaccggc cgtcagatcc actggcggcg ggccgcctgg acccccgcct cgaagcggct
     1321 ggaggcgccc aggcgctcca tcagctcggc catgatgcgg cgttcggtgc ggaccccgat
     1381 gccgagggcc cgggccaccg cctcgtcggt gaggccggtg gcgaggagct gcaggagttt
     1441 gcgctcctgc ggggtgaggc cctgcgggtc ctcgtcgggg gactgctgat ggaacggcgt
     1501 cgcgtgttcc cagtacgcct cgaacagggc tcgcatggcg agcaccacgg ggcggctgtg
     1561 gaacatcagg gcggcggggc ccgtctggcc gggcaggttg gccacgatgg ccgcggtcgt
     1621 gtcgacgatc agcaggcgca tgggcagggt cggcgaggtg cggacctcgc tgttgtgctc
     1681 cgccatccac tgcgcgtggg ctctggtcac ccggtcgctg acggcgctgt cgaggtagat
     1741 cgagcggaac cggacgcccc gggcgagcgc ccgttcgttc agcggacggg acgcctcgat
     1801 ggcctccttg gtcagtccgc ccacggggtg gaagaccagg gactcctgct ggcacgactc
     1861 ggcgagggcc tccagccgga tgcggatctc gtccacgttg tcgagctgct cggtgccgtc
     1921 cgagccggac ccggccgagg ccgtgtactc ggcggcgagc gcggcgagag cggcccggtt
     1981 ctgctcgatg cgctgctgcc gccaggccag ttcgtcctgt tcccgctgga gcaggacctt
     2041 cagtccgagc gaggggttca ccgcgcgcag cgtgccgggt gagtctcccg agggagcgag
     2101 cagcgacagg tccgacaggc gcgtgagcgc catgtgcacg tcgtcgcggc cgatgtcgag
     2161 gagctcggcg agcttgtccg gatcatgttg cttgtggaac aggatcgcgc ggtacaccgc
     2221 gagggtctgc tgatcgagcg gcgatacgtc gtccacgtgg cgtctccccc ttgaaccaca
     2281 tgtgaaccgc atgtctggac cggaccgccg cgccggctgg agagcggcgg cgcggctcgg
     2341 gggagcagcg cagggtatgc gaagaacccc cgtagatcgt tcacatattg gccacgttac
     2401 ccgctcagga gttccggtgt cgcacacagt cgcacatgta ctaccgccgt tgcacggctg
     2461 tgtcgtcctc gtcgtcgacg ccaccaccgg ggtcggccgg cgggtcacga gtcagctgtg
     2521 cgcgctgggc gccgcggtcg ccgtggtcgg tgccgggcac ccggggcgtg atgacgacgc
     2581 cgccaccaac gcggcgttcc tgtgcaagga actggccgga atcgggttgg tcgcgttgcc
     2641 gtatcaagcc gatgtggaac ggcctgagag cttccgcgcg ctgaccggtc agatcgccgc
     2701 cgacctcggt caggtcaccg cgagtgtcgt ggtcgtgccg tcggcaagcg gaggcgaggg
     2761 accggtgcag gccttccgcg tcgcgtcggg tgtggtcgcg gcctccctgc cggccggcgc
     2821 cgagcacatc gaggtcgacg tgagcggcca gggcttcagc ctggaagagg cggcccagtc
     2881 ggtggtggag cggctggtgc ggctgcacga gcagtggcgc accccctccg ggtgacggcc
     2941 ggcgcctgtc atgttttccc gagtctttgc cttagtcctg ccgtacgggg gtcgagcatg
     3001 tcgatacgca tagtcctcgc tggtgatcac caactcgtgc tggaggcctt cgccgagacg
     3061 ctcaacggcg tcgacgggct ggaggtcgtc ggcctggcca cgtcgtacga ctccgtccag
     3121 ccggccgtgg agcggcaccg gccgacggtg ctgctgctcg gcgagtccac gatgggcggg
     3181 aaggcgttgc gcgtcgcgac cgacgtgcgg agccggcatc cccggtgcgg ggtggcgctg
     3241 atggtcgggg cggcgacggc gtcggtggtg gaccgggccg tggcggccgg tgcgctgggt
     3301 gtcgtgccga agaacgcccg gctgccccag ctggtcacga cgctgatggg cgtcgcgggt
     3361 ggctgtctga ccgtcgaccc gtcgctgctg cggccggtcg ccgtcggtga actctctctg
     3421 agcacacggg agatggacgt gctgcggctg acggccggtg gggcgacggt gaaggagatc
     3481 gcgggcgagc tgtatctggc ggcggggacg gtacggaatc tgacgtccgc cgcgatcaag
     3541 aagctcggcg ggcgcaaccg gttcgacgcg gcgcggatcg ccggggaaca cgggctgctg
     3601 tgagggtcgc gcggttggtg ggcggagcac gggttgctgt gaggggcgcg cggatggtgg
     3661 gcggagcacg ggttgctgtg aggaccgccc ggggggcggg cgggaaacgg gctgcggtga
     3721 gggtcgcgcg ggcggtgggc gaacgtgcgc cggccccggc acagagggtg ccggggcggg
     3781 gcgttggtgc cgtgcgagcg ctggtcgggc tggtgcggtg gatgtgcggt gaggtgccag
     3841 ggtcacttct ccaggcagaa ctcgtcgatc gggtagccga catggcggtc ggcggtgggc
     3901 aggtgcccga ggatggtgtc gccgggcttc agctccgtgg agttgaggac ggcggcgttc
     3961 gggccgagga cgcgcacgtg ccagtcgtcc tggaggatca ggttgaccgt ctgcccgctc
     4021 ggggcgaccg cgtcgatgga gatcagcgga cgggtctcga tcttgacgcg gccgacgctg
     4081 acgggccggg tgcggccctt gacgtcgacg gccagcacct tgctgccggc gtggagttcg
     4141 ctgaggtagt gggtgcggcc ggcctgcgag acggtgtacg agtgcagggc gccggcgttg
     4201 acccggaagg ggcgggtcgg catgtacggc agcgggtggg tctcgctgac gcacagcacc
     4261 atgcccttgg agtgcgagcc gacgaggatg ccctcgtcct tgcggaagtg ggtcgtggtg
     4321 tcgacgcagg cccgctcccc catgccgatg tgcgtggtcc gggtgacggt gagttcgacc
     4381 aggtcgatct cgccgccgcg ggcgctggcg gcggtgcgca gggcggtggc gtcgccgacg
     4441 gtgttggccc gcatcaggac gccgtccgag cccaattcca ggacgccgta gatgatctcg
     4501 gcctcctcgg tgttggacgc ggtggtgatg atggagccgg gggcgccggt ggcggcggcg
     4561 atcacgatct ccagcgggat cttggtgggg tcgcggaagt cgagcacgct ccacggctcc
     4621 aggcgggccg cgaggcaggc gtcctccagg gtgtcggcgt cgacgatctc cacgtagcgg
     4681 ccgaactcga cgtccgggtg ggcctcctgg agcgccgccc gctcctcacg ggggccgggg
     4741 acgacgacca ggtcggcggc gccgaggtcg gcggggacgg cgtcgaggcc gtcctcgaag
     4801 agcaggacct tgcggacggt gggaggcagg ccggcgaagg cggccgggtc ggcggcgacg
     4861 atgccgtcga tgcgctggtg cagggcctct tcgaggacgg cctgggtggc ggtgccggcg
     4921 cctcggatgt caagccagca cagttttgcg tccgtcatga tgcggacctc ctgtcgggtg
     4981 tgaggagtac gaagggtcgg agaggtggtg cgtgtcgtgg tcgagcgggg agccgggcgc
     5041 gccggggtgg gccggggcgt ccaggtgatc gggggtcagc cgctcggccc ggtgtgcgtc
     5101 ggccgggaag gcgagcgggg cgaagtgctg ctccgggaag tggtggatca gccgggcgac
     5161 cttggcggcg agccgccgcg ggtcggaggc ctggaagatg ttgcggccca tcgccacccc
     5221 gcccgcgccg ccggccaggg cgtcgcggac gtaggccagg acgtcctcct cggtgggcat
     5281 cgcggggccg cccgcgacga gtacgggcac cgggcaggcg gcggtcaggt cgagcatctc
     5341 cgcggtcgag ccgaggaaga cggtcttgac caggtcggcg cccaggtcgg aggcgacggt
     5401 gacggcgtgc gccaccaggt ccgggtcgcg cgggtcggtc acccgggggc cgcgtgggta
     5461 caccatggcg agcagcggca ggttccaccg atcgcaggcg tcggcgatcc gtccgaggtc
     5521 gccgatctgc tgccgctcgt cgtcggagcc gacgttgacg tggacgctca ccgcgtccgc
     5581 gccgagccgg agggcctcct cgacctgcgt caccacgtac ttggcgtcgg ggtcgagcgc
     5641 ctggctggtg gacgcgttga gatggatgat cagcgacatc gcggcgaacc gctccgggct
     5701 gatgtgccgg acgctgccct tgtgcacgac gaccgcgtcc gcgccgccgg cggcgagctg
     5761 cccggcgagg tggtcgaggc tggtgccctt gggtgcgacg ggcccgtcgc tgatcgagtg
     5821 gtcgagaggg gtgatcatca ggcctgccgt gctgtggcgg tagagccgcc gcagcctcag
     5881 tgacctggcg aagtggccga atgcggtcat gggatgccct ttctgttgcg cggatcggta
     5941 cgcgtacgcc ggtcggtggt ccggcgggcg tctggtccgg cggtaccgcc ggggtcgggc
     6001 ggaccggtgc cgcgtcgctc cgcgggtggc ggagcggggg cgcctgccgg gcgcgtcggc
     6061 ggcaggccgt ctgcctggcg cgtcggcggc gaaccgtccg ccgggcgcat cgacggcagg
     6121 ccgtctgcct ggcgcgtcgg cggcgaaccg tccgccgggc gcatcgacgg cacgccttcg
     6181 cccgggcgcg tcggcggtgg gccttcggcc agcgggtggc gcgccggggg gcccacggcc
     6241 ggggggtgtc ccgccgggtg gtctacggcc ggggggatgg gctccgtcgc ggctgacccc
     6301 gtatcggaca ccgaccccgt cacggacacc cgccccgcaa cgaaccccgg ccccgtcgcg
     6361 gaccccggcc ccctcgcgga cacccgcccc gtaccggaca ccggccccgt accggacacc
     6421 ggccccatcg tggacaccga ccccgtcgcg gacaccggcc ccgtaccgga caccggcccc
     6481 atcgtggaca ccggccccgt atcggacacc ggccccgtcg cggacacccg ccccgcaacg
     6541 aaccccggcc ccgtcgcgga ccccggcccc gtaccggaca ccggccccat cctggacacc
     6601 ggccccgtat cggacacccg ccccgtcgcg gaccccggcc ccgctgagga gccggtgacc
     6661 cgtttcggtg gagcgtctcc cgtggggcgg gcccgtaccg gggtcgtgac cccgcgcagc
     6721 cgtgcacggt ccggttttcc cgatggggtg agcggcagtt cgggccagac cgagacgctg
     6781 acgggagcgt gttccggggt gagggtcgcg gcgacgtagc cgcgcaggtc gcaggaggtg
     6841 tggccggcgc cggagtggag ttcgacggcg gcgtggacct gctccaccaa atcctcgtcg
     6901 tggacgccga acaccgccgc ctgccggacc tgcgggtgcc gcagcagggc cgcctcgatg
     6961 gcggcggggt cgagcttgag gccgccgtgc ttgatgacgt cgccgacccg gccgtccagg
     7021 cggaggtagc cgtagtggtc ccagtgcccg aggtcgccgg tgcgcagcca gccgtcccgg
     7081 taggtcgcct cggtgagctc cgcgtcgtcg aggtaaccgg ctgacaccgt cggcgagttg
     7141 acccagatct cgccggtccg gccgcggccc agcggggtgc ccgagccggc tgcccggatc
     7201 tccacgcgta cccagggaaa gggacggccg gccgagccca gcagttcggg ctcgcggtgg
     7261 tcgagcgggg tgaggctgct gatgccgcct gcttcggtgg tgccgtagac ctggatcagt
     7321 acgtcgccga agacgcggac cgcctgccgg acccgctcgg gggcggccgg ggtgccgctg
     7381 taggtgatgc ggcgcagcga cgacaggtcg tacgacgtga ccagcgggtg gtcgagcagg
     7441 cggtacaggt gtggcaccgc cacgtagacg tcggtcacac ccagttcggc gatggccgtc
     7501 agggtcgcgc ccgcgtcgaa ctcgtcgtgc aggacgaccg tgccgcctga gcacagcacg
     7561 gcgtcggcca tgggtgccgt cgtgtggctg accggtgtga cggacagcag tgtcgccggg
     7621 ccccgggggt cgaggccgga ggccagccgg ccgacgaggt gctcgcgggt gccgtagcgc
     7681 tgggcgacca tcttggggcg gccggtgctg ccgctggtga agtcgacgac ggccaggtcg
     7741 ccggggtgcg gcggcggggc cggcggcacg gtgtcgtgcc cgtccgccgt gcgcgggatg
     7801 gcccgcacgg tcaggccggg ccgtcgccgc gccagccatc tgccgcggga cgcgctctcc
     7861 tcgtccgtgt cgtccacgag cagcagcgac accccgaggt cacgcagcag cccggtctgg
     7921 gtggcgaccg agaaggtctc ggtgtccgtg cgcgggttca tcgagcggac gtagacggag
     7981 gtggcgccga gcagatggac ggcccagcgg gcgctgagca tcagcgggtg gttggggccg
     8041 gtcaggatgg cgacggtggt gccggggcgg acgccgtggg agtgcaggag cgccgcactg
     8101 cccaggacgg acgcgtgcaa ctcgcctgcc gtcaccgtgc gttccggccg gtgcaggacg
     8161 atgcgggtcg ggtccctgcc cagcgccgcg aggacgcggc gcgcataggg gcggggaatg
     8221 gcttcggtgg tcatggccct cctttccgaa ggaagaagtc ggttccggga atcaggcgat
     8281 cttcatctgc gccatcattc ccatggcgct gtggtcgatc atgtgacagt ggtacggata
     8341 aacaccgcgg tgcgaatcga aggtgagctg gagtttcgcg gtctggccgg gaaagagcag
     8401 cacggtgtcc ttccagccgg tttccgccgg ataaggcggc tgcccgtccc gctcgagaat
     8461 gcggaactgc accagatgcg tatggaagtt gtgcgggacg gtggcgctct tgttggtcac
     8521 cgtccagacc tcggtgctgc cccactcgat gtgggtgtcg atgcggtccg ggtcgaaggt
     8581 cttgccgttg atgtaggcct ggtggccacc ggagccgggc tcgtccatgg agaggtcgaa
     8641 gctgcgttcc acggtcggtt tcgccagggc cggcagcgtg gcgagggtgg cggggaccct
     8701 gctggtgtcg gcggtgcgtt cgccgacgtc gaaccgcatg acctggccga cgagttcggt
     8761 cggccccggc ccgagcatgt tggcgagggt gagctcggtg ccgggcgcgt accgcgagaa
     8821 gtcgacgacg aagtcgatgc gttcgcccgg ggagaggacc agcacgggcg tctcggcggg
     8881 ggcggcgagc aggccgccgt ccgtgccgat ctgctgcacg gggtgctggg tggcggaccc
     8941 gtcggacagc gcgaggatga agatgcgcag gttgcaggag ttgaccagcc ggaagcggta
     9001 cttgcgcgcc tcgaccttca gacggggcca ggggcggccg ttgaccagga tggtcgtgcg
     9061 gttctccggg tcgtccatcg tgtacaccag ttggtcgttg tcgtcgaagt gcgcgtcgcg
     9121 caggaccagc gggatgtcgt acttcccgga aggcaggccg agccggtcct cggcggggtc
     9181 gcgcagcagg tagaggccgg acaggccccg gtagacatgc tcggactcca tgtggtgcgc
     9241 gtggtcgtgc gtccacaggg tggcgccggg ctgcttgttc tcgtacacgt aggtgcgtct
     9301 gcggcccggc gcgatggtgt ccatcatccc gccgtcgtgc gccaccgggt tgttgccgcc
     9361 gtgcaggtgc acggaggtcg gcatgtccag ggcgttgatc tgctgcacga cggtggtccg
     9421 gccggtgcgg gcgcggatgg tggggcccgt gaacgtgccg ttgtacgtca gggcgtcggt
     9481 gcgggtgccc gggaggatct ccacgccggt gcggcgcatc gtgatccggt agtggtcggc
     9541 ggtcttggtg cggcggtacg gggcgaggac cggcgggatc gtcaggggca gggagaaggg
     9601 ttcgacgggg gcggccgccg cgccggccgg tgcggccttc ccggccgccg tgccctgccc
     9661 tgcggcggtg agcgtccgga agaccccgcc cgccgcgccg accgcgccga cggcgccggt
     9721 ggtgaggccg agacgtatcg catgtcgacg actgaacacg aggttttcct tcgctgtcgg
     9781 tgagttgcgg ggagaattcc tgttccgagc atgcgctgcg ggtgccgaat gtccgagcga
     9841 tcgaagtccg cccctgtcat ctgtcatgca ttccatgacc ccggtcacga gcgggaatgg
     9901 cgactgtcat tcggtgcggc cggtgcgggg ggagccggtg tagcgggccg cagagtggat
     9961 ttcgacaggt ccgcccacgc aagtccgtac cggaggcccg atgaatcccg caggcacgaa
    10021 agcgatcacc gagaaacccc ccgagtccgc cgcccgggcg ctgcgcggcg acgtgcgggt
    10081 gacgttcgac gacggcacgg acacggcgct gctgcgaggt cccgtcacct ctctcgccct
    10141 gcgcccggtg cgcggcccgc tgcgcggggt cctgctccgg ctggccgaag gcccgctgcc
    10201 gcgcgaggag ttgtacgagg gcctcgacgc cgccgggcgg aagcgcgccg acgccctgct
    10261 ggagcgggcc gcgcagctgc tggcgtacag cgtgctgacg cacgacgagc cgccgctgcg
    10321 gcgggagttg gtccggctgg agccgaccgc gcgggacgcc gtgcaccggg tcgcggacgt
    10381 ggcggccggc gaccgcgtcc ggctctcccg gttcgcgttc tgccggacgc gtgacggcgt
    10441 gctcgtcctg gagtcaccgc tggtgaagtt ccgcgcggtg ctggccgacc gggccgcgcg
    10501 tgaactcgcc gccgccctgg ggcagcccgg ccgggcgggc agcgccgggg aggtcaccgg
    10561 gctgagcgag gcggagaccc tggacgtgct gtcccacctc gtcggtctcg gtttcgccga
    10621 gctcgcgggc ccggacggca cgttcgcctc cgacaccgaa ccggtgctgc gccagtggga
    10681 cttccacgac ctgctgttcc actcgcgcat ccgctcgggg cgttacgacg gtgtcttcgg
    10741 cgccgtctat ccgtaccggg gcgagatcga cccggagccc gccgtgaagc ccgcgccgcc
    10801 cggcccggtg accgagctgt accgcccgcg gcgcgccgat ctcgacgccg ccgacccgtc
    10861 actgaccgcc gcgatcgagt cccgccgctc ccaccgcgcc ttcggggagc gggcgttgac
    10921 ggcacgcgag ctgggcgagt tcctgtaccg ggtgcagcgc gtgcgcgtgc accgcacccc
    10981 gggcccggac tcccccggcg aggacgaggt cgtctcgcgg ccgtacccga gcggcggctc
    11041 cctgtacgaa ctggagctgt acgccacggt ggtgcgctgc gacgggctgg agccgggcat
    11101 ctaccactac gactcctacg cgcaccgcct ggtcctggtc agctccgagg aggcggcccg
    11161 gcgggccctg ctgggcgtcg cgtcccgctc ggtgggcttc gacgtccacc ccgacgtgct
    11221 cttcaccgtg acctcgcggt tccagcgcat ggcctggaag taccgggcga tggcctacgc
    11281 gacgacgctg cggcacaccg gggtgctcta ccagaccatg tacctggtgg ccacggcgat
    11341 gggcctggcg ccctgcggac tgggcaacgg cgacgccgat ctgtcggcga gggtgctggg
    11401 cctggactac ctgcgggagt cctccgtggg cgacttcctg ctgggtacgc cggccggcgg
    11461 caccgagccg cccgccgacc cgggcgagga atggcacatg gtgaacagcc ccgactgggc
    11521 aattccactc gacggccccg gagagccggg cggcggcgaa aagtcactcg caccgtgata
    11581 aatgtcagcc ggcggcggcg aaccctggcg ccgggatgac ggcccgagca atatggatgt
    11641 cagagccgga cgggaaagga aagaaatccc ggaaggcgac caggaatgca cggccggatt
    11701 ttccggtgac ggatatcccc ggcctcgacg aaaggaatgc gacatgaccg ccaaggacat
    11761 caagaaccag gacgcggaca aggcgttcga gggcttcgac gcggacgagc tggagaccct
    11821 cgaggtcacc gacggcgtcg ccctgccgga gatgggcgcc tccagcggct cgatcggcac
    11881 ctcctcctcg tcctccagca cctgctcggc ctgctgaacc actcatcccg gatcttcgga
    11941 aggatttcga catgaccgcc aaggacatca ggaaccagga cgcggacaag gcgttcgagg
    12001 gcttcgacgc ggacgagctg gagaccctcg aggtcaccga cggcgtcgcc ctgccggaga
    12061 tgggcgcctc cagcggctcg atcggcacct cgtcctcttc gtccagcacc tgctcggcct
    12121 gctgaaccgg cgtcacggca ccagcaccac agcgtgaacg cgtcaaggat gcgcctgtcc
    12181 ggccccggcc ggccgggcac atccttgcgt tcagcgctgg gcgcgcgtca gccgcgcagg
    12241 gccaggtggt acgacgaggc ccacaacacc agcgcgctgc ccaggcccac cacgatccgc
    12301 acggtctcgc tcgcgaggcc ggccgcgacg agcacgaacc cggcgaccgc gacggcggtc
    12361 agcagcgacg ccgtccaccg gtactgccac tggtcgtaca ggcgggcgag cgggaagaag
    12421 tgcaggccca cgacgagggc gatgcccgcg gggatggcct cgggccggcc ggcggcgttg
    12481 gacgcggcga tgacggcgaa gatggccgcc agctcgacgg tgttgacgat gcccacgccg
    12541 cgcgcccagt tggccggcag gttcaccatc cgcggcgagg gcgcggcgcc cctgcggtac
    12601 cccaggtaga tcgccgacgc cgtgagcagc agcgccgccg cctcgatacc gagcggcacg
    12661 gcgtccgtcg ccgagccggt cccggaggcc gccgccaggg cccacatcag ggcgaacagg
    12721 gagagcacca gcacgcctcg gcggcgcagg ttgcgggtga gcgcgaggca ctcggcgtcc
    12781 gtggcggacg gggtgggggg tgtcgtgggg gacgtagatg tcactcgcgg agaatacacc
    12841 ggccggtcgg ccttcttgac ggttttcggt cagcccatcg gcgcctcgaa gcggaatgca
    12901 acattccgac ctcgcaccct cggacgggcg tcacggaaac gatgacgtat gtaagcgccg
    12961 gaccgttttc ccttccggct cgaattcccg ccgccaatca tgggtttcac gttctcgaat
    13021 tcattgcggc tcttctcgga aggtgaaagg acatgggggt tcacgctccg gagcgcattg
    13081 ccgtgaggcc ggattccgcc ggcctgacgg gggtgcgact ccatactcgg atgccggtga
    13141 caccggcctg gctggcccgc cacgtcgtcc cggtcgcccg cggactgggc gagcggggcg
    13201 tgcccggcgt gcaggtgcgc cgcggctggc tgcacgggcc gcacgtcgac gtgctcgccc
    13261 cggccggcgc gctgccgccc ggcggcgccg tcgactgggc ggcgatcgag gccggctggg
    13321 acgccggccc cctcgacccg gcccgggcgc tgaccgagga ggtgtacctc gaccaggccc
    13381 gcgagttcgg ccggctggag gcggtggagc cgccgtacct gccgctgcgg gagcacggcg
    13441 cggttctgcg cgtcggcccc ggcgatccgg cgctgcgctc ccgggagccg cgcctcgacg
    13501 ccctgcgcac ggtcgtgcac ggcgccctgg cggcaccggt gctgacgatg atcgagggcc
    13561 tggccgagga gccgggcagc ggcacggtcc gcctcgcgga ggcgttcgcc gccctcgtcg
    13621 acacccatgc tctggggccc gcctacgggg tgttctcgcc ccgctcgcac gtggaggcgt
    13681 tcctcgcctg ggcggctccc cgcaaggaca tgcgaccggt cttccgggag cggctcgcca
    13741 aggaggcgcc ccgcatccgc gaggtcgtcg aacagcgcct gagcggtgcg gtgtcccctg
    13801 cggccgccca gtggcgcacc gcgttcgcct acggcgccgg ggtcctggac cacgccgtcg
    13861 ccacgggcgc cctcacgccg gacctgctcg actccgtcac cgacggcgtc gaccgcagcc
    13921 ggatgggccc gcccggggcg gaggcggtgg tgccgcgcgg cgagcagccg gacaccgact
    13981 tccaccggac cgtgcacggc tcgggggcga tcagcacccc gtccccgttc ttcgccgcct
    14041 accgcctgct gacgaacctc ttctaccagc agctgcccct gctcacggtc tccccgatgc
    14101 agcgctacta catgtgcttc gcgctcgccg agaccgtcga cgacgtgctc ggcagcagct
    14161 ggcgggagcg cctcaccgcc acgcgaccga cgggagcccc gcgatgacca gccccgaacc
    14221 ccagtggttc ctgcgcgtca acccgctgcg caggacccgc ctcgccgacc cggagcagcg
    14281 ccgcctgctc gcagaactcg cccgggccga ggccgagttg gccgaggtcg ccgaggtgtg
    14341 ctcgcaggag ctctacgagc ggatcggcgc ggccggctcg gacgccgagc ggcgcgagct
    14401 gatcgcgctg cgccgcgccg tccacaacgg ccgcgccgcc aagaagacgc ccgagagcct
    14461 cgaagcgacc ccgtcggtcg cccgctggct ggccgcctgg accgggcggg agcgcctgcg
    14521 caccgcggtc acgcagggct acccggccgc ggccgaccgc gaacgcgccg tactggccgc
    14581 cctgctgggc gacggggacc tgctgcgctc cctggcgctc atcgcccccg aggtgcacca
    14641 ggaggccgag cgctaccggg ccgcggtcga gggcccgggc aaggtgtccg cccggacccg
    14701 caagtccgag cgcggcctga tccagtacgt gacccgggcg atggtgcgca ccagcccact
    14761 ctcccggttc accgcggtgg gcatcgccga accggccccg gccggcgacc cggacgccgt
    14821 ccgccccggc gaggtgccct tcaccggcgc gcacgcggtg ccgggcctgg accgggtcat
    14881 gctccactac gtcctcggcg gcctgcccgc cgacgacacc gacccgagcg ggctctgggt
    14941 ggggatgccg cccacctcgg cccccgaccc ggagtcgggc aagctgttct tcctgaagtt
    15001 ctccgagcag ggcatgcacc gcctcgcggt cccgctcgac gggcccgtgg cccatctgct
    15061 cgacgcgctg tcgatggggc cgcgcaggtt cccggccgtc gtcgagcacg tcgccgcccg
    15121 ggccggctgc tcagccgagg aggccgaggg gcgcgtacgg caggccctgc accagggcgt
    15181 gctgtgcacg ttcacccggc ccgaggagga gaccgccgca ggcgactacg acgacctgct
    15241 gacccttccc gacgtcgaac agccgcccgg agtacgggag ttggcgaacc gggtgcgcgc
    15301 cggactgcca cgggtgaccg aggccccggc cgccgggcgg ggcgcgctgc tggccgggct
    15361 gcgcggggac ctcggccggt tcagccaggc ggcgggccgc ccggcgcaca tcacggtcga
    15421 ggaggactac gtcatgccgc cgctgaaggt ggcggcctcc gactggcacg ccccgctggc
    15481 cggcctcggc ccggcggtgg agctcctgac cgtcttcgac tggctgcacg acgtgcgggt
    15541 cctgatgacc gccgcgttca cggagcgctt cggggccggg gcgaacgtgc cgctcgccga
    15601 gcacgccgcg ttcatcgtcg gggaggtctc ccggcgggcc gccgcgatgg ccgccgtgta
    15661 cgggcccggg ggcacggggc aggccgccgc gctgtccggg atcggaccgg ccgacggctg
    15721 cctggagcgc atgtacctgc tgcgccgcga gctgtccgag gaggtgcacg ccctcctcac
    15781 caagaccgcc caggccggtg aggacaccct gcggctcacc gcggcggacg tcgccgagct
    15841 gacccgggcc ctgcccgacc gcttccgcag cgacccgctg atctacggcg tgctgctcca
    15901 gcaggccggc gaccagctcg tcctcaacga cgggctgccg ggccacggca tgctgtacgc
    15961 acgcttcctg gaggccgacc gccgccaggg cggccgcgcc ctgccccgcc tggccgagca
    16021 cctgcggcgc ttctacggcc atgacggcac ccgcatcacc gaggacctgg gcctgcaccg
    16081 cctcaacgtc aacgcgcaca ccccggtgct gccgggcggc ctcacggccg aggactggtt
    16141 cacgctgcgc ctggcgcacg acccggagac cgacacgctg cgggtcgagg acgccgacgg
    16201 cgccccgctg cgggtgctgc cgctgggcac cggccacccg ggcctgttcc cgccgccgct
    16261 gtcggtcgcc tccggcctgg tgatcagcgg ccggctcttc aacagcctgc ccaactcctg
    16321 gcacgcgacg accccgtggg acggcaagca cacccgcgtg gctccgcgca tggccgtcgg
    16381 cgacgtcctc atcggacgcc gtcgctggta cggcggtgcc gaactggaca cggccgtggc
    16441 cgccgggccc gacgaacacg aacggctcct cgccctgacc gcctggcgct cccgccacgg
    16501 cgtccccgag gaggtcgtca tcaagtcggc gccggaggac gagggcccgc tctcggtggg
    16561 cgcccccgac gtccagtcca agcggctggc gcagaagccg cagtacgtcg acctgtccag
    16621 cgccctggcg gtgcgggtcc tgccgcggat gctggagcgc cgcggggccg gcacgagcta
    16681 tctggaggag gccctgcccg gcgtcacgga cggcacccac gccacggagt gggtgctcga
    16741 agtgggccgc acggccggag gccacttcga gtaccacccg gccgacggcg gggcagtgga
    16801 aggagtccgg tcatgaccgt caccgatgtc gagaggaccc cggcgcggac ggcttcggat
    16861 gccgtgccgc tcatggcccg gcccgggctg cactacgcgc ccgtgccggg gggcgtctac
    16921 ttcagcggca cccgcgggca gttcgtgctg cgcggctcgg agctgctgta cgcggtggcg
    16981 gacggctgtg tgccgctgct gcgggcgggg acgacggagg acgccctggt cgccgagttc
    17041 ggcaccgagc gggcccggcc cgccgtacgg catctcctcg gcaagctccg cgagaacggc
    17101 ctgctgctcg accccgccgc gctcaccgag ccggagccgc cggccgagct ggccgcccgg
    17161 cacgccggca ccctggcgcg cctcaccgcc cgcctcgacg acccgtacgc ggcgttcgcc
    17221 cgcctgcgcc gggcccgggt gcggctgcac ggcccggcga cggcgacggc cccggccctg
    17281 cgcggactgc gccgggcggg cgtgaccgac gtgacggcga cggccgttcc gctcacgccg
    17341 acgtccctgg tcccggtctg cgaccccgcg atgtacgcgg accccgccct gctgtccggc
    17401 aggccgggac cggcaggcga ctccggcccc ctgttccccg ccggcgcccc ggcggcgcac
    17461 caccctccga ctcccgccgg cgacccggcg gtgaaccaac ccggcacgcg aacccccgtc
    17521 ggcgacccga cggtggatgc acccggcaca ccaacccccg tcggcgaccc ggcggtgcac
    17581 caccccccaa cccccgccgg cgacccggcg acgcaccaca ccggcacacg aacccccgcc
    17641 ggcgacccgg cggcgcacca acccggcacg cgaacccccg tcggcgaccc ggcggtggcg
    17701 gcgtctgtga tgggcgaggg cgtgcccggg gtcgtcgtcg agtttctcga cggtgaccgg
    17761 acgtggaccg agggggacgg cacgctgcac gtgcccgtgc tgctcgggcc cgggccggtg
    17821 ctggtcggtc ccgtcggtgt cgcacccggc gtctgggagg tcttccggga ccgggtcagg
    17881 gcctgggcgg acgccgaggg cgtcgagccc gcgaccgggc cgatcgccca ctccctcgcg
    17941 ggagcgctcg ccgcgcagct cctgaccgac accctcacgg gtgtcgcgga gcccggtgag
    18001 gcccacgtcg tgcacggacc ggatctgacg gccgaccgcg tcaccgtcac gggcgccccc
    18061 gtgagcgaag cggtcgccgt ccggctcggc gacgcccccg ccgagccctt ccccgccccc
    18121 gaggacgcgc tcggcgccgc cggggtcctc accgcccgct ggaccggtct cttcgcctcc
    18181 ccgcagggcg aggacctgcc gcagatgccc ctggccctgc gcgcggccga gcaccgggcg
    18241 gaccgtacgg gcacggtcac cgcctgggcc gcccaccagg agacggcggt cgtcgccgcc
    18301 gccctggccg ccctgcgcga ccgcggcacc cgcgcctccg gcatcccggc ggcgggtctc
    18361 acccgcgagc actggctgct ggacggcgcc ctgcgccacc tcgcccgcca ggacggggac
    18421 ggccgcgacg cggacacccc gctgcacgcg gaaggccgcc gcatcctcgc cgaggtgcgt
    18481 gcgctgctcg gcgaggccga acccgtcctc gccgtcacgc ggtacgccgg tgtcggctgg
    18541 ccgctggccg aggtcaccgc cgccgggcgg ccgctcggcc gcggctgggg cccgaccgcc
    18601 gccgacgcga cgtacgccgc gctgtgcacc gcactggccg tcgcacagag cggcggcacg
    18661 gccgaccggc tctccaccga cgccctgctg acggcggacg acaccgcccg ggcggcgctg
    18721 cgcgagcagc tctcggcgat cgccgtccac gcgggccacc cgcgccgcac cgatccggtg
    18781 ctcggcgaac tccccttctg gcacggcccg gtgaccgtcc gcgccgtccc gacgaccgcc
    18841 gaggagtccg gcgatgcaga ccactgatgc gatcaccgcc ggcccggccc tgcccccgac
    18901 ggcgtacgac gactggctcc ccgccctcgc gcccctggcc cgggccaccg gggccaccgt
    18961 ctccgtcaac ctcggctggg acctgacctg ggaacgcgac cgcgtcacgc gggccggcgg
    19021 cccccacctg tccgtgcggg tgtacgacga cgaggtgatg gtgggccccc tgtgggtgcc
    19081 ggacaccgcc gtcggctgtg ccgcctgcgc cgaggtgcgc gaacgcaccg tcctcgacca
    19141 cccgctcgtg ggcgacctca cccaggccat gcgcgtcccg gcgggccccg caccgctcct
    19201 gcccgaactc ctgcgcaccg gcctggacca cctggccgct caccccctcg cgccgggcga
    19261 ggcctactcg gtgacggtcc gcggcacccg gcggcaccgg atcgcccgca gcttccactg
    19321 cccggcctgc ggcccctccc gcgaggacct gacgaccacc gaggcccccg cgccccgccc
    19381 gctcccctcc cggcccgccg tgcccgggga cgccacccgc accgccgcga gccgtctcgt
    19441 cgagcccggc ttcctgcggg accggctcgt cgacgaccgt ttcgggccgg tccgcgcgat
    19501 cctgcgcgag tcgcacgccc cgttcgcgat gagcatggcc gtcgtcgcgg acgccccggc
    19561 gatgggccac ggcagggccc gtacgttcgc ggagaccgaa ccggtcgccg tcctggaggc
    19621 gtacgagcgg ctcggcggct acccctacga catccccctg ctgaccggcc gctcgtaccg
    19681 cgaggtcgcc ggacaggccg tcgacccggg cagtctcggc cgctacaccg ccgagcagct
    19741 cgcccacccg accagcaggg cgacgccgtt caccgccgac accccgatgg actgggcctg
    19801 ggggcacgat ctggccgacg gcacccccct gctggtgccg gccgaccatg ccttctacca
    19861 gtacgagtac gcctttcgcc gggaccggcg ggcggcgcgc gtggccggcg ccgccaaccg
    19921 ccggcactac ttcttcgact gctccagcgg ctgcgcggtc ggcgccaacc acgaagaggc
    19981 cgccctgcac tccctcttcg aactggccga gcgggacgcc ttcctgacgt cctggtaccg
    20041 ggcggagccg ctcccccaca tcccggtcgg caccctcacc gaccccacca gccgggccat
    20101 ggtcgagctg atccgggcac gcggctacga cgtccatctc ctggtcgcca cccgggacat
    20161 cggcctgccg gtggtgtggg tgatcgccgt gaacgagaag gaccccttcc cggcgacctt
    20221 ctcctccgcc ggttcgggcg ccgaacccga gtccgcgatc cgcggggcgc tgcgcgaggt
    20281 cgcacagctg gtcaccaacc cggtggactg gacgcgcgag caggtcgagc ggatggtcga
    20341 ggatccgtgg ctggtggagg agctggagga ccacgtgcgg ttctcctcca tccccgagac
    20401 ccggcaccgc gccctggccg gactgggcgg cccggccgtc accctggagg aggcgttccc
    20461 ggactggccg ggacggctgg agcgcgcgtc cggcggtgac gtccggggca ccctccggta
    20521 cgtggcctcc ctcttcgccg acgccggcct ggaccggatc gtcgtcgtcg accagaccag
    20581 ccgggagcac gccgacgccg gtatcgcggt ggcccgtgcc gtcgtgcccg gcatcgtgcc
    20641 gatgtgcttc gggcacgccc agcagcgtct ggacggactg ccccggctgc gcgccgccct
    20701 gcgcggcacg ggccaggagc accgggcgat cccctacgac ccgcacccgt tcccgtgacg
    20761 gcccccgccg agccctggac gcggcgcgcc ccggtcgacc tgccgggccc cgagggcgac
    20821 agcagcatcg cccgcgagcc cctctggtac gcctacggcg ccggcgacga cgccccggaa
    20881 ccaccgccgt ggacctggac cgccacaccg ccgcccgatg cccacgtccc gcccccgcca
    20941 ccgcgcccgc cggggcccgc gaccccgctg ccgccgggca ccaccgaccg cctggcggcc
    21001 ctgccgtacc cgtggctccc ggcccccggc ccggcgtcgc cggaggccct ggcccacgcc
    21061 ctgaccgcca cgttcgcgcc cctgcgccgc gaaccggaga acccgtacaa cgaacaccgt
    21121 tcctacgcct caccgcgctg cctgttcccc gtgcacgcct tcgtcgggga cggccgtgac
    21181 tggcgcctgc tggagccgac ccgccacacc ctcacgggcc cgggcacggg cacccccggg
    21241 cgcatcgccc tgaccggccg ctacaccgcg atcccccggg cgtaccagtg gttccggggc
    21301 tcgctggtgg cgatcgagac gggcctggtg ctgcgcgcgc tgagcctggg cctggagctc
    21361 ttcgggctgc cggcgacgct gacgccgccc accgcggacg gcccggagct gctgcgcgag
    21421 ctcggtgtgg agcacacctg ggagtggtcg ctgccgtggc tggtcgagct ggacgagccg
    21481 cagggcgcag gtcgcgaagt gaccggcttc aaggagcctc cggtccccgg gggcgaccct
    21541 tccctcaccg acgtggtccg tgccaaccgg gctcagccgc acggacccgg gggcgcgggg
    21601 aaccgcgcga ccagccacac acagcccgcg cccgtcacca cagccgtgcc ccccaccctg
    21661 cccgactccc cccacgcccc cacctggtcg gacctcctct ggcaccgcca ctccggccgc
    21721 atgcccagag ccctgcacgg catggactcg gccaagtgcc tcacccccct ccccgcccgg
    21781 accctgacca cggccctggc ctggctggga gtccccccac cgcacccgct cctggcggaa
    21841 gccttcgacg cggtcaccgt caccgccgtc gtccagcaca tcgacggcca cacccccggg
    21901 atacaccgca tccacgacgg caccgcagac ctgctccggc gggaccccac cgcccccgcc
    21961 ggtctggagg ccaactacgg ctacggcctg acgccggtca acggctgcgg catcgccaac
    22021 gcccccctca ccgtcttctt ctcggtccgg ccccgcgaac tgttcgcccg cttcggcccc
    22081 gccggctgga gcgccgccca gcatgcctgc ggctgggcgg tccacggcct gtgtctcgcc
    22141 gccgccgcgg agggcctctt cgcgcggccg gtacgggcgt tcaaggagat ccagaccaag
    22201 gaggtcctcg gtctgggcga ggacgagacg atcgtcctgt cggcggtggc cggggtaccg
    22261 cgcgagaccg ggggtgccgt gctggacctg cgtacataag gccctggaac acagcccacc
    22321 gaccggacaa ggaacacgca tgcccaccac accgcacgac tggagcgcct ggcacctgca
    22381 cctcggcacc accgcccgcg gcgcccacga ccgcgtcctc acggacgtca tcggccccac
    22441 cgtcgccgaa ctcccgcccg cgacgccctg gttcttcatc cgctactggc agtcgggccc
    22501 tcacctgcgc ctgcgcgtcg cggacctgtc cgcggacgcg cacgcgcatg tggagcgggc
    22561 cctgcgcgac cggctcgccg aggcgggccg gctcgcgccc ggcgaggaac cggtggcgga
    22621 ggaggcctac cagcagggcg cgtcccggct ggccgccgcc ggggagaccg gcgccaacac
    22681 caccgtccgg gcgctgctgc cgcccggcgt gcaccgcgcc ggctacgacc cggagtacga
    22741 gcggtacggc ggcagcgccc tgatgccggc ggccgagtcc ctcttccacc tctccagcga
    22801 actggtcctg cgtctcgccc cgctcgtcac ctccgaggcc cgccgcgccc ggctcgccct
    22861 gcgcggcacg ctgtccgccg cggtcgccct cggcggcccg gacgaacgcg cccactactt
    22921 cgcgcgcggc cgggacgcct ggcgggcctg ggcgcgcgac gcgggtcact ccgccgagct
    22981 gctggaccgg atcaccacgg tcgtccagga cccggccacg gccggtgtcg ccccggacgc
    23041 acacggcccg ttcaccggct ggcacgaggc cctgaccgcc cacgccgccg agatccggcg
    23101 gcactcgccg gtccaccccg gcatgatcct cttctcgcac gcgcacatgc tccacaaccg
    23161 cctcggtctg agcctgctgg aggaactgcg tacctacgcc tggctgtccc acgtcttccc
    23221 cgtgccggcg gcggcaccgg gcctggcgcc cacggggtga tcccccgcgc ccgtgggcgc
    23281 ccgcgcagag gcccggccgg attcccctca ccggccgggc ctcgtcgctg tgtgcgacgc
    23341 acggctcgtc cctcccgcac gacggcgacc cgcgcccgcg cccgcacccg cacccgcacc
    23401 cgcacccgca cccgcacccg cacccgcaca gccgtacccg gtgcaccgcc gtcccccgcg
    23461 ggccgccgct cccccggggg gccgccgctc cccggggcga caagcgccga gggggcctcc
    23521 tgggaggccc cctcgatggg gtcggaacgc gcccggctct actcggggcg cggatcccag
    23581 cggaagctgc gcacggcgat cagggcgccg acgacacccc aggccgccaa cacggccagt
    23641 tccttccact ggaagccgcc ctggtgcgcg aacggcgcga gcatggcgtc gttgaacggc
    23701 ttcaccggga gcagcccggc gatgttgttc atgacgtcgg agtggatggg gaagtagctg
    23761 ccggagatga acaccagcgg gaactggatg aactgcacga ccgcgggtgc cgcctcggag
    23821 ttgcggatca gcgaggccac gcccacgccg agggcgcaga agctggccgc gccgagcacc
    23881 agggtgagcg cgagggccgc ccagtcggcg ggccacggca ccccgtacag ccgtccgatg
    23941 ccgatgacca gggccacgtc cacgacactg acgacgacgc agtgcacgag cagccccgcg
    24001 aagtacaccc aggcgggcag cggggtggcg tgcagccgct tgaggacgcc ggtctggcgg
    24061 cgcatggcga ggacgatcgc caactggccg tagcaggcgc ccaggacgga tacggccgcg
    24121 atggccggcg tgtagtactg cagtccgctc aggccgaaga agaagtcctg gctctcgctg
    24181 ccggcgaaga cggccccgaa gaccgagatg atcacgatgg gcaggacgaa ggtgaacacc
    24241 atcgactgcg ggttgcgcca gaacgacagc tgctcgtagc ggatctggtg ggcgagcagg
    24301 gcgagggagc cccgttcgtc gggccgttca cgtccggcgc gttcggccct tcgtgcggtg
    24361 gcggtggtcg tggggggcag ggtgctggtc atcgtcggct ccgtccgggt cggcgccctc
    24421 ggcgggcgga cgccgccagg gccggtgtgc tgccccgccc ggtggacggg gacgaggcgt
    24481 cctgctccgc gtacgtactg gtcagcccca ggtagacgtc ctccagggtg ggctgctcga
    24541 cggtcagccg ctccaggggc gtgccccggt ccagggccca ggaggtgagc cggtgcaggg
    24601 cggcggtcgg ctcctcggcc tcggcggtga cgaggccgtc ctcggcgtcg ctgaccggga
    24661 tcggcacgtc gtcgatggcg gcaccggccg gcagggcgaa ccggatgcgg gcgagggcgc
    24721 tgtcgcgtcc gccgatggtg tcgggcgtgc ccgcggcgac gatccgcccg ccggcgatga
    24781 cggcgacgga gtcggccagg gcctgcgcct cgtccatgta gtgggtggtc agcaggatgg
    24841 tggtgccggc gtcgcgcagg ctccgtacga cctcccaggc tccgcggcgg gcgcccgggt
    24901 cgaagccggt ggtcggctcg tcgaggaaca gcagcttcgg gtcgccgatg acgccgaggg
    24961 cgaggtcgag ccgccgcttc tggccgccgg agaggtcctt gaccttggcg tcccgcttct
    25021 cttcgagccc cacgaggtcg atgacctcgt cgacgccgcg cggggccggg tagtagccgg
    25081 cgttgcgggc gatggtctcg cgcaccgaca ggtacggctc gacggcgatg tcctggagca
    25141 cgagcccgat ctgcccgcgc agccaccgcc cgtcggcctt gtcgccgggg tcgcggccga
    25201 ggacccggac gtcgccgccg tcgcggtggc ggaagccctc caggatctcc atggtggtgg
    25261 tctttccggc gccgttcggt ccgaggaggg cgaagatctc gccctcctcc acggcgaagc
    25321 cgacgccgcg cacggcctcg tggtccccgt acctcttgag caggccgtcg acggccaccg
    25381 cggtcaccgc ggtcgctcca cttctcgttc gcgtgtcacc gcgtgcctcc aggtgtagta
    25441 acgggtgttc tccttccgga agttagggcc ggtcgggggt gcggcagcag gcgtggcggg
    25501 ggtttcgatg acgtccgtca cgcaagcggc gacagttgtc agcacggcgg gggcatgacg
    25561 ttgccgcccg ggggcgggcg ccacatgctc ggggacacga ccgatgacag tgcgtccacg
    25621 tcgcccgcgc cacggcggtg acggacgtga cgccaagacc cggaaggcgg tccccgaggt
    25681 gctgttgggc gaagacacag gagggcggcg gctgcccggg aactccgcgg agccgtccgg
    25741 cggggagcgg ccgacggtcg ccgtcgtcgg cgcgggcatc ggcggactga ccctggccgg
    25801 cgcgctgggc gcgaacggca cgccgtacgt gatccacgaa cagacccgcg aactggcgga
    25861 ggtgggcgcc ggcgtccagc tctcccccaa cgcgatccgg ccgctgctgc gcctcggcct
    25921 cggtccggcg ctgcgggagc acggggtgcg gatcgaggcg atggaggtac gcggctggaa
    25981 cgggcggccc atcgcgcgca cgccgctcgg cgccgactgc gagcgcatgt tcgccgctcc
    26041 gtacctgacg atccaccggg cgcatctgca cgacgcgctg ctctccctgg tcgaccggga
    26101 ccggctgggc ctcggccagc ggctgagcgc ggcgggcgaa cggccggacg ggacgggcgt
    26161 acggctcaca ttcgacgacg gttcggtgcg cgaggcggac gtggtggtcg gcgcggacgg
    26221 catccactcc acggtccgtg agacgctgcg ccgcgacgag ccggtctact cgggcctggg
    26281 tatctaccgg ggtctggttc cggtggacgc gcttccggcc gaggcccgcg agcgcctggt
    26341 gcggctgtgg ctcgggccgg gcgggcactt cgtcgcctac ccggtcgcgt ccggcacgta
    26401 cctcagttac gccgcgaccg tgccgctgcc gtccgacgcg ccgccccgcg agtcctggtc
    26461 ccggcccggt gaccccgacg agctgcgggc ggtcttcggc tcctggacgg gcctggtcgc
    26521 ggacatcgtc gcggccgtgg agacgaccca ccagtgggcg ctgcacgacc ggccgccgct
    26581 gcgcacctgg tccaccgacc gcatcacgct actgggcgac gcggcccacc ccatgctccc
    26641 gttcatggcg cagggcgcca accaggcgat cgaggacgcg atggacctgg cggcctgcct
    26701 cgccgacgca ccggccgggg cgatcgcgga ccgcctggcc cgctacgagt cgctgcgcat
    26761 cccgcgcacg gcggaggtcc agcgcggctc ccgtggcaac gcgggcatcc tgcacctccc
    26821 ggacggcccc gcccagcgtc gcagggacgc gcagatggcg gtgcacgcgg ccctgcggga
    26881 ccgtgcggcg ctctacgcgc acgagacggg ccgcagcgtg gttccggctt gacccggtga
    26941 ccgtgctccc ccattacggc tgcgtcgagg gcatacgcac cttcgaccag ggcgggagcg
    27001 tgcggcagtc gaagcggacg ggcgccacca tcgcggccgg gaaccacttc gaggcgtggg
    27061 cccgggccgg aatgccgcat acctgagtac gcgtgctcat gacgggcccg gtgccatccc
    27121 ccgatcctgg tcgtatgact gatcggggaa tggtggcggc cggggccgcg ctcgtcggtg
    27181 gtgtgcctgt ggccgcctgg gggctgatgg ggcagcagaa ccacgacggg ctgccggccg
    27241 gtgagctcga ctacgcgttt cagccgtggg acatcgggga cggcgtggcc gccgtcgccg
    27301 ggggctcgcg ctggtgctgg cggtggccgg tgcggcggtg ctcgtgcggg gcacgctgcg
    27361 cggggcgatg gaccggcggt ggtggggggt gctcgggccg ctggtggtgc tcggtctcat
    27421 ggtcggggtg gggtggcgga tcctgaccgc ggggggcatc ggggccaaca tcggagccgg
    27481 actgctgatc atcttcggta ccccggtcgc cgccgggctg ctgctgtggg ccctggcctg
    27541 ggcgttctgg ctggtcaccc agcgccacgg gcacgagggc ggcggtgacc tgggcggtat
    27601 cgcctcccgc ggggtgtagc agcgggccgg tcgtggccga aaccgcacgg caggcgtccg
    27661 gcaggcgggg caacgcccgt atcgcatcgg gaagttcgcc taggttgggg gccggtcccc
    27721 cttccccgcc ctccaggagg ccccaccgtg tccgacgaca gcctgcgtga tcgcatcgac
    27781 acctccaagc cgcactcggc ccgcttctgg aactacttcg tcggcggcaa ggacaactac
    27841 gaggtcgacc gcgagatcgg cgaccagatc aagtcgatct tcccggggct cgtcgacgtg
    27901 gcggtcacga gccgccgctt cctggggcgg gccgtcgagt acctggccgg tgagcagggc
    27961 gtacggcagt tcctggacgt gggtaccggg ctgcccaccg ccgacaacac gcacgaagtg
    28021 gcccagcgcg tcgctccgga ctcccggatc gtctacgtcg acaacgaccc catcgtgctg
    28081 gcccacgcca acgccctcct caccagcacc cccgagggca ggaccgccta cctggacgcc
    28141 gacctgtacg acccggaggc cgtcctgaag gccgccgccg gcacgctcga cctctcccgg
    28201 ccggtcggcc tgatgatcct caacaccctg ggccacgtcg ccgactacga gcgggcccgc
    28261 gagctggtac ggcggctcat ggccgggctg ccggccggaa gccacctggt gatcagcgac
    28321 agcaccgcga ccagcgaggg catgatcgcc gcgtcggagg cgtacaacgc gagtggtgcg
    28381 gtgccgtacc acgtccgtcc ggtcgccgag atcgccgggt tcttcgacgg gctggagctg
    28441 gtggagcccg gtgtggtgag ggtgcccgag tggcggccaa gggcttttgg tgacgccggt
    28501 ttcggtgacg gcgccgtgga cgcgtactgc ggggtagggc gcaagccgta gggcgttcac
    28561 caggtccggt gcggcgtcgt ggggctggtc gcgcagttcc ccgcgtccct gagcgcgtca
    28621 cccgtccggt ccggtcgccg cagcccccgc ccgcccccac gcgataatca ggacatgccc
    28681 gcccctccct ccgtccccga gcccgccggc cggctcctcg gtgatctgct ggcggtggga
    28741 gaggcctact ccctcgtcct cgccggcgga tacgcggtcc tggcgcacgg gctcctggag
    28801 cgggccgggc cggccgtgga cgccgccacg gagcacccgg ccgcgatgga ggtcgtcgcg
    28861 gacaccgtgc ggaccgggct ggtcgggcgg ggctggctcg tgcagaccct ggagaccggg
    28921 ccgctgtccg cccagttcct cgtcaccgac gcggcgagcg gcgtggagtg cgaggtcgcc
    28981 ctgcacaagg aggtgctgtg gcggccgccc gtggagacgg aactcggccc ggcgctctcc
    29041 ctccacgacc tcgtcggcac ccgggtgcgg gacctggccg accgcggact cgcgcgcgac
    29101 ctggtcgacg tacacgccgc ctcggcccgc tggagccacc ccgagctcga agaactcggc
    29161 cgccgccacg cccccgacac cttcgacctc accgacctcc acgcccggct gaccggcacg
    29221 gactggctcg acgacagggc gttcaccgtg gccggcctcg acgccccggc cgtcgccggg
    29281 ctgcgccgct gggcccagga gtgggccgac gacatcgccg aacgcctcat cgagggcgag
    29341 gccccggacg aggagtgaca cacacgcccc gcacgtcgac agaccggtcg gtaccctgac
    29401 ccgatgggga acggggcagc cggacaggtg ggggtcgtcg ccgcgctggt gcgtgcggcg
    29461 ttcctggtcg acggtgtgta cgcggaggcc agccgggcgt acggactgac gccgcagcag
    29521 gggcagttgc tgtgtgtgct gatgtcccgg ccgtacggca tgagcgaact cggcgagacg
    29581 ctggggctgg cgaagtcggg actgaccggg ctggtggacc ggacggtgcg gcgagggctg
    29641 gtacgccggg aggccgaccc gcgcgacgga cgggccgtgc gggtgggact gacggaccaa
    29701 ggagccgcgc tggccgggaa gttctacgcc gagacctgcc gtcgtatgga ggcgctgccg
    29761 tccgggctga gcggcaccga gcgggaccgg ctggcccgtc tgctgtcgag ggtcgtcgtg
    29821 gacaacgagg ttcccgaggt gttcgtggag accgcgaccg tctccgcttc cggcggctca
    29881 ccctcctgag agcccgtcag cggctcaccg ccctcggctc ctcccgcttc gccgcgccca
    29941 tcagcagcag cgtcaccccc gcggacgcca cggccatcgc ccccatcgcc acggcggggg
    30001 acgtcagttg ggcgaccgac cccgcgagcg ccgccgccac cccctgcatc gtgagcatcc
    30061 ccgccgagtg cagacccagg gcatgccccg tgagcccgtc gggggtgagg gccaccagtc
    30121 gctcctgctg cacgaggctc gcgccgaacc ccacggaggc cagcgcgacc gcggccgccg
    30181 cgagcggcag cgccggacgc agcaggaaca ccacgtacgg ggccgccagg agcagcagga
    30241 gcgggaatcc caggcgggag cgcaggccgg atgggagcac gcggcccacc agcacgtccc
    30301 cggcgagcat gcccagcgcg gcgcaggcga agagggtgcc ggcggagtcg ggggcgtagg
    30361 agacgtagag ggattcgcag ccgacgacca ggccgttggg gatccacagg gccagataga
    30421 cctggcggcg gggcggggag gaccagagca gcgcgttggc gcgccaagtc gccgccaccg
    30481 aggggcggcc cgtcgtacgg ggcgggcggc gggtcaggcc gaggcggacg acgacggccg
    30541 ccgcgccgta cagcccggcg gcggccagca gcgacaaccg cggggacagc agggccacga
    30601 gggcgccgcc ggccgcgtaa ccggcgatct gcatgacgcc gctcatcatg ttgaacaccg
    30661 agcggccgag cagatagccg tccttggaga ggatctcgtt gagcaggccc cagcgcactc
    30721 ccccgcccac cgactccacc agccccttgg cgaggacgac cacgaagagc ccccaaacgg
    30781 gcattgcggg cagggccagg gcggcggtgg ccgcggcgaa gagcagcggc agggccgtca
    30841 gggccgcgcg cgggggcagc cggtcggcgg cggagagcag gagggtcgcg cccagcacct
    30901 gcaccagcga ggagccgaac atgctcaccg cggacagcag cggtgagccg gtcgcccggt
    30961 agaccagggt gcccagggcc agcccgccca tggtctgggc gacggtctgc gccgacgcgg
    31021 ccaggaagaa cggggtgaac tcgggcgtgc ggaacagttc gcggtagctg cgcatgggcg
    31081 gagtcttcga cgccctctga tcgcgtggtt attgtttcgc gcggacgcga aacctcgcga
    31141 agagggggtg ggccatgggc tggtggcaga tcagcgccga caccctggcc gggagccggt
    31201 tcgtgatctc gccgttcgcc gaggccttcg cgagcctgcg gctgctgcac gcggccgacg
    31261 cggcgcaccc cggcgagcgg cggtggctcg acgcccattt gccggcctac cggcggcggc
    31321 tggcccggga cccggtgacc gcgcagctga tccgcgccgg gatcgggcgg gagtggacgg
    31381 cggacttcct ctcccccgcc ccgcgtgacg gagagccctt cgagcaggag gtcgcgcggg
    31441 tgcgggcggc cgacccggaa gcggcccgcg ccgacctcac cgtctcgctg cgcggcccgg
    31501 tccccgcggt gctgcaccgg gacgacctcc cggagcgcgc cgcggacctg ctgacgtacg
    31561 tctggaccac ggcggtgcgg ccgtactggt cccagcgccg gcacatcctc gaagccgatg
    31621 tggtcgcacg caccgcgcgg gtcagccggg gcggctgggc gagcgcgctg gacacactgc
    31681 ggccggggac gcagtggctc ggggagaacc ggctccaggt gaacgcgcac gaatacccgc
    31741 cgcgcgagct gtccggcgcc gagctggtgc tcgtgccgat caccacgcag cgcatcggct
    31801 gggtggcctg ggggggcacg gaccggtacg cgctggtcta cccgtgcgcc ggggcactcg
    31861 ccgactcggg cggcaggccc gcgcccgcga gcctcggcgc gctgctcggt acggctcgcg
    31921 ccggtgtgct ggtccggctc ggctcgccgc tgagcaccag ccagctggtc gccgtgaccg
    31981 ggcaggggct cggctcggtc gggcggcacc tgcgagtgct gctggacgcc ggtctggtgg
    32041 agcggcggcg ggcgggcagg tcggtgctgt actcgcggac ggcggcgggg caggttttgg
    32101 tggaggccac cgaggcccgg aactcaccgg agctagggtc tgaggcatga cgactaccaa
    32161 cggttcctct cccctcgacg tcgagatcgg tgcgctgcag ggcggtccgg ccgacctgtc
    32221 ccagtacgcg ggcaaggcgg tgctcgtggt gaacgtcgcc tccaagtgcg gcctgacccc
    32281 gcagtacacg ggcctcgaga agctccacga gcagtacgcc gcgcgcggct tctccgtcct
    32341 cggcgtgccc tgcaaccagt tcctcgggca ggagcccggc agcgccgacg agatcgccga
    32401 gttctgctcg gcgacgtacg gcgtgacgtt cccgatgacc gagaaggtcg acgtgaacgg
    32461 cgacgaccgg catccgctgt acgaccgcct gaccggcttc gcggacgccg aggggcacag
    32521 cggggacatc cgctggaact tcgagaagtt cctcatcggc cgcgacggcc gggtcgtggc
    32581 ccgcttctcg ccgcagaccg agccggactc ggcggagatc gtgacggcga tcgaggccga
    32641 gctggcctga cgtcccgctg cttgaccttg cccctggggc aggcccgagt gtcctcgtcg
    32701 tcgggcggaa gagccgcccg acgacggagg atgccgtggt ggacggaccg aaccaggact
    32761 tgctcaccat cggggcgttc gccgcgcgcg cccgcctgtc ggcgaaggcc ctgcggttgt
    32821 acgaccggct gggcctgctg gccccggcgc atgtcgacga ggccaccggt taccgctact
    32881 accgggccgg gcaggtcgaa cgggcccggc tggtggccat gctgcggcag ctggacatgc
    32941 cgctcgcccg gatcgccgag gtggtcgagg cgggcgacgg ggccggggcg gccgagctgc
    33001 tcggcgcgta ctgggcggat gtcgaggcgc gggtggcggg gcagcggacg ctcgccgagt
    33061 acctccgtgg acggctgtcg gggaggagct ccgagatgta cgggaagttc acggtcgaga
    33121 cggtggaggc acccccgcag gtggtgatct ccgagaagcg gcacacgctc gcggacgagc
    33181 tgccggcgtg gatcggggcg gcgctgggcc ggctggagga ggcggcccgg gagtgcggag
    33241 gcgtggccgg ggtgccgtac
//
