LOCUS       NZ_CP014504            25614 bp    DNA     circular CON 03-MAR-2024
DEFINITION  Pedobacter cryoconitis strain PAMC 27485 chromosome, complete
            genome.
ACCESSION   NZ_CP014504
VERSION     NZ_CP014504.1
KEYWORDS    GSC:MIGS:2.1; RefSeq.
SOURCE      Pedobacter cryoconitis
  ORGANISM  Pedobacter cryoconitis
            Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
            Sphingobacteriaceae; Pedobacter.
REFERENCE   1  (bases 1 to 5950539)
  AUTHORS   Lee,J. and Kim,O.-S.
  TITLE     Complete genome sequence of Pedobacter cryoconitis PAMC 27485
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5950539)
  AUTHORS   Lee,J. and Kim,O.-S.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAR-2016) Division of Life Sciences, Korea Polar
            Research Institute, 26, Songdomirae-ro, Yeonsu-gu, Incheon 21990,
            South Korea
COMMENT     ##MIGS-Data-START##
            alt_elev                          :: 1 m
            assembly                          :: SMRT Analysis v2.3.0
            collection_date                   :: 2014.01.03
            country                           :: Antarctica
            depth                             :: 5-10 cm
            environment                       :: soil
            investigation_type                :: bacteria_archaea
            isol_growth_condt :: 0.1x Tryptic soy agar, celsius degree 20
            lat_lon                           :: 62.236389 S 58.71772199999998 W
            project_name :: Genome sequencing of Pedobacter cryoconitis PAMC
            27485
            sequencing_meth                   :: PacBio RS II sequencing
            geo_loc_name                      :: King George Island
            env_biome                         :: ENVO:01000186
            env_feature                       :: ENVO:00000097
            env_material                      :: ENVO:00001998
            ploidy                            :: haploid
            num_replicons                     :: 1
            ref_biomaterial                   :: not applicable
            source_mat_id                     :: PAMC 27485
            biotic_relationship               :: free living
            trophic_level                     :: chemoheterotroph
            rel_to_oxygen                     :: aerobic
            assembly_name                     :: ASM118778v1
            finishing_strategy :: complete; 110x coverage; 1 contig
            annot_source                      :: prodigal v2.6.1
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 110x
            Sequencing Technology :: PacBio RS II with P6-C4 chemistry
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 09:48:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,049
            CDSs (total)                      :: 4,958
            Genes (coding)                    :: 4,943
            CDSs (with protein)               :: 4,943
            Genes (RNA)                       :: 91
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 15
            CDSs (without protein)            :: 15
            Pseudo Genes (ambiguous residues) :: 0 of 15
            Pseudo Genes (frameshifted)       :: 3 of 15
            Pseudo Genes (incomplete)         :: 14 of 15
            Pseudo Genes (internal stop)      :: 2 of 15
            Pseudo Genes (multiple problems)  :: 3 of 15
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:50:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5777972
            Orig. end                         :: 5803586
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP014504.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25614
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="19"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25614
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25614
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15614](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15614
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    complement(321..333)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
     misc_feature    323..333
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            565..789
                     /locus_tag="AY601_RS24485"
                     /old_locus_tag="AY601_4941"
     CDS             565..789
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AY601_RS24485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AY601_4941"
                     /product="hypothetical protein"
                     /protein_id="WP_068406499.1"
                     /transl_table=11
                     /translation="MIITENNTPYNNEEEEDDQLSQQDVQSDGIDAIPPSETDTLATEI
                     ENLKQADKSSEAAYTLDADRGIAPKKEEE"
     gene            897..1724
                     /locus_tag="AY601_RS24490"
                     /old_locus_tag="AY601_4942"
     CDS             897..1724
                     /GO_function="GO:0016603 - glutaminyl-peptide
                     cyclotransferase activity [Evidence IEA]"
                     /GO_process="GO:0017186 - peptidyl-pyroglutamic acid
                     biosynthetic process, using glutaminyl-peptide
                     cyclotransferase [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016952.4"
                     /locus_tag="AY601_RS24490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_4942"
                     /product="glutaminyl-peptide cyclotransferase"
                     /protein_id="WP_068406502.1"
                     /transl_table=11
                     /translation="MYNKYKVLAFGLAITLASCQNNNKETKAVATAADATSTQVPKNLT
                     YKVAGTLPHDTAAYTEGFELHGGKIYEGTGTYENSYVAVSDTSSGQLEKKFPLKDKSIY
                     GEGISILGNQLFQLTYQNHIAYVYDLKDLTKPTGTFKWPQEGWGMTNDGKNLYVSVGSS
                     IIYKLDPKSFAVVGQIQVTDNLGTVDQLNELEYVDGFLYINQWQTTKILKVDVSSGKVV
                     GTIDCFGLLSNYAPDYTPKSEDSVLNGIAWDKTHQLLYVTGKNWPLIFKLRLD"
     gene            complement(1893..2588)
                     /locus_tag="AY601_RS24495"
                     /old_locus_tag="AY601_4943"
     CDS             complement(1893..2588)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="AY601_RS24495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_4943"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_068406509.1"
                     /transl_table=11
                     /translation="MLQAIELTKKYGDQVALNGLNLNVEPGEVFCLLGQNGAGKTTTIN
                     LFLGFTGASSGKALVNGVLVSPDQPETKKFLAYIPEIVMLYANLTSLENLDFFSRIAGF
                     NYKKEELEKYLLQAGLQPEAFHKRVGNYSKGMRQKVGIAIAVAKNAEVILMDEPTSGLD
                     PKATHEFSEIVKQLSKDGRTVFMATHDIFNAVNVGTRIGIMRQGSLIHTLNAKDISAND
                     LQKLYLETI"
     gene            complement(2601..4787)
                     /locus_tag="AY601_RS24500"
                     /old_locus_tag="AY601_4944"
     CDS             complement(2601..4787)
                     /GO_function="GO:0015267 - channel activity [Evidence IEA]"
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1051:
                     TonB-dependent siderophore receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR01783.1"
                     /locus_tag="AY601_RS24500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_4944"
                     /product="TonB-dependent receptor"
                     /protein_id="WP_068406516.1"
                     /transl_table=11
                     /translation="MKKIFYLFIFSLSVLPNLLYAQQPKKLTDTTGQLNKLEQINVTSK
                     KKVRIKTDTLSNSLKLQQPLIQIPQNIISISTGLLQQQGALELKDAARNASGVYFGYNS
                     TPFDNSAVAQIRGFAAYTTLNGMSRRFSYGASIDDDALIENVEFVKGPAGFLNSVGEPG
                     GSINILTKTPGHKMLNIVQTAGSFNLYRIAADIGSEVQKKGFSYRFNTAYQHKDSYLND
                     LKTNKYVVAPVIQYNFSPNTYVLAEYDFIRGEVQNGSAIVKVRSEQDILKGPISTNYSS
                     ERSLPTSYTQNETARIYAVHKFNDNWQVTSQSSYLSSPYKNWNMTSKGSMVNFDANGNT
                     KRRASLSMGAGKTFSTQLFANGQLKTGGIQHQLLIGADYTNSRDSLSLNNGKIESDYNK
                     SGTINTARAETVNQITRINRTNNNTFIKSAFIYDNIQLQKKLLLTLGARYTWYKNDKET
                     TNARGVVKTNNYDQKALSPRAALTYLVNPATSIFFLYDQSFVPQSYQRAIVDPTTKEIT
                     GTEAIDPQKGKDMELGIKRNWFNSRLYTTLNGFHTLKSNVPVTDLINAGFVKPAGQVTS
                     NGIEVDVIGNITDQLSISTNYTYVKSTITKDEDPELLGKELPQTPQQIFNTWVQYSFPL
                     RNKASLNLSLGQTTMIKRSTSEKNQYIPDFTKYDAGLSYVQDKYFFRLIADNLTGKRYM
                     SSGDLITGYPYDGRNFYYIDGDPFNVKVSIGIKF"
     gene            complement(4816..6270)
                     /locus_tag="AY601_RS24505"
                     /old_locus_tag="AY601_4945"
     CDS             complement(4816..6270)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024091.4"
                     /locus_tag="AY601_RS24505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_4945"
                     /product="DUF3526 domain-containing protein"
                     /protein_id="WP_068406518.1"
                     /transl_table=11
                     /translation="MQLFLLIFRFEWRQFLRQPVQLLLLLFFLLMSVYSLYNGQSFVQK
                     QLTGLDTLTNNQQANLQELISRFHTDTTTAQGKILAQQAGLPKVVEFKAPPIATNPPQA
                     LAALAIGQRDLLPYFDIISSKRDILTPPNAEIANPEKLASGNFDFSFVLIYLFPLLIII
                     LSYDLFSREAEQQTDRLLAVQSGAINRILRHKILFRLLLISLLTNMLSIIGFFIHPAAA
                     ALHLPDVLLWILVTNTYLIFWFAVCWLMIILRKSSQLNALILIGIWLLLTLILPAITNK
                     FAGLKYPMPLRTELVSNQRQTMTHTWEMPIPQLLKEFYQNNPQYLSLKTDGDTARYGNK
                     RFVAYYDLLGRRMNKNVMEYTTAAAKHNAWLSQMAWLNPVAQMQALLNATAQTGLSDYL
                     YYQNQTSLFQNQWVKLINGYLLSNKKLSLIEVQNLPAFHPAKDQTRTSRILVNTLSIWL
                     AILLTLLIARQIANQIAFKRKNKSTY"
     gene            complement(6273..7700)
                     /locus_tag="AY601_RS24510"
                     /old_locus_tag="AY601_4946"
     CDS             complement(6273..7700)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024091.4"
                     /locus_tag="AY601_RS24510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_4946"
                     /product="DUF3526 domain-containing protein"
                     /protein_id="WP_068406524.1"
                     /transl_table=11
                     /translation="MSPLQYTPLRTLIWKELRLAFRDKIMSTLAIIIYTLFIASGLLTV
                     LQYQNDQQSRELSNKKFRQQWEAQHNNPHEAAHFGTYLFKPLNLLSAFDPGLNDYSGTT
                     YRVEAHVQHEVDYSNAERNDALMRFGQFTLALIMQMLIPLLLLFISSSALTYEKESGTF
                     KMLMAQGIKPSQLAWGKVWSNYLLVVFLVMPIFVVLFFVVLCSPSGIALLGRFLILLCG
                     YLLFYLLVTLTGVIVSALSGTSRTATLTVLTVWLFSSILFPKIAAGHAADQYPLISRAA
                     FNNNVKQGFLKGINGDAPYHERAEKHYAALLKKYGADSAAQLPVNADGLMLQYNEDYQN
                     KVFDHYYTALANTFNQQQSSLNYAGLADPFMSLKRLSMAMSGTDFYHHQSFFLQAKEYR
                     NNLIRKLNLQLASHPVKPNESYQASPRFFLQLKDFSYQAPTLLETLYLQRLALGSLCAW
                     IALLSMALYFITKPSLQ"
     gene            7780..9984
                     /locus_tag="AY601_RS24515"
                     /old_locus_tag="AY601_4947"
     CDS             7780..9984
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="AY601_RS24515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_4947"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_068406527.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 6.3e-29, bitscore:
                     98.7, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQLFSSGRKFPFYKQPDAMDCGPVCLKIISAYYGKTFPIAYFRK
                     LCSIGKQGTTMTSMLEAAGLLGFKTLAAEIPYEQLLNRVRLPCILHWEKEHYVVLYRMT
                     SKYAYLADPALSGKVKVRKEDFIRSWQIKEGSTIGRALLLETTPAFQEKQSIADHSASL
                     WSLMPYLKLHRKSLIPVGISLLLACGFSLIIPFLTQLIVDKGIQGKNTNLLFLICIGQL
                     MLFSGRMLMDFLRARLLFRLGARTSIVLLKEFLAKLMQLPFSFFDNRQAGDNMQRVNDN
                     QRVEEFLTNSLISFILSAITLVVLGGVLCYYNWQIFLIFLIGAVISVTWSNSFQQKRKV
                     IDQKKFKVLSANQQLLLEIFYAMQEIKLTGSEQEKQELWEGLQDQSYGLKLEALQLDQL
                     MQGIGYFINEVKNVLITYAAAMLVINDQVTLGGMLAITYICGQLNTPITQLVEFARVSQ
                     NTKFSLQRMAEVHQEAEEDFEVGYRDMTSAPENIELKQVSFQYGNSHAPFVLKNLDLLI
                     PAGKVTAIVGMSGSGKTTLIKLLLKFYQVSKGSVTIGNLSVDQVHAKQWRAACGVVMQD
                     GYVFMDTIANNIFAGSVVKDKERLYEVSKLANMHDFFMAMPFGYDTVVGKDGYGLSEGQ
                     KQRLLIARLIYRNPAYIFLDEATNSLDAHNELSIVNNLNNFFTGKTVLIVAHRLSTVKN
                     ADQIVVLHQGELVEKGTHQELIARKGNYYQLIKNQLELSK"
     gene            10001..12727
                     /locus_tag="AY601_RS24520"
                     /old_locus_tag="AY601_4948"
     CDS             10001..12727
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="AY601_RS24520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_4948"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_084359456.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.5e-43, bitscore:
                     147.1, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 8.4e-07,
                     bitscore: 27.8, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIEIFPHSLVRYAGMNYQVFDSFKLKGSKGILQKDHQMKAAKTK
                     LKALICDGLFELITLQTDDLLRQQLINLKRQVFNDKKVNPQKLEELLGLFPADLTLDFH
                     NYLQVSQNMETFHQTNTLNYQQLLMEQSKKLQELAMDPHLQNGLLLSSPVLLEQLPGYL
                     QKEPASFRQKELRIEFSLLRYLTRMCFKTSPFSTFTYTGIMQLADNGAVIPSPMAKAVK
                     NSLRLNNALFEYLKSILIHHPGVNELLTVKLNKTATIKAGKIQFLVNFNNIESFQLLPA
                     SGLQLLVFNYFNSAQESINIKELANYMAYAVEEANYTSIKNYLLKLVAAGLLEVGMETS
                     GIDPQWSLKLLNFFTKLESSEPAVLQIIYLFKQLQQYQLAYAKGDTAKRKLILAYAEKT
                     VAAVFQKLQAEAGLPLSRDTTKEVDDQSKKQAVNGVFETQNFIPHHFSGRQLFYEDCYT
                     PELEILEDGCLQDFAAKADQLLNHLLPLDLLKTEREKMSSFFLEHYPAQAQVKVIDFYQ
                     AYYFYVKKPEKEKSAKLGPAIPDPSEWEKTISEKLALITQHKPNILNLGNDFFPEALST
                     EAPVAAVQYSRGLFVQFYKGKLQQEAEHKECFFGVINTVLPGMGKVSGRFLPLFTPDMT
                     TDFVKYNTQLHPEVLKVELNDASSFNANIHPSLLTRELALPGGNKSYPEKQQLPVDGLT
                     VSFEQQTSALKLNYQQEQVFTYDLCLESFYNRSNLYQLLAHFNQDTKLSLQPFINLVDA
                     CYLDVEEQEQEIESLPRITYENSVILRRRTWRIKTASIPVQQAGENAYAYFIRINTWRA
                     QHGIPVTFFLFLRKRSFVIKPAAQPNGKKEGLSDDYKPQFISFEQPLLVEMFKRLLARA
                     GTHVIVEEMLPLTNAATDQAGYVEPVKEYLLQWYKYE"
     aSDomain        10754..11017
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AY601_RS24520_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="4.80E-09"
                     /identifier="RREFam001.1"
                     /label="AY601_RS24520"
                     /locus_tag="AY601_RS24520"
                     /protein_end="339"
                     /protein_start="251"
                     /score="27.8"
                     /tool="antismash"
                     /translation="KLNKTATIKAGKIQFLVNFNNIESFQLLPASGLQLLVFNYFNSAQ
                     ESINIKELANYMAYAVEEANYTSIKNYLLKLVAAGLLEVGMET"
     gene            12724..13650
                     /locus_tag="AY601_RS24525"
                     /old_locus_tag="AY601_4949"
     CDS             12724..13650
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03891.1"
                     /locus_tag="AY601_RS24525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_4949"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_068406532.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.2e-39, bitscore:
                     134.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMERKDKAVQYQWFAAYLFYPGDLDLMLRELVAPFIREFFPDEQT
                     DAQYFFIRYWENGSHIRLRINVEYALHQVLAKALEQKTNDFFSQYPAVRKLKDSLNQPV
                     SQPLAADHAIQFSVYEPEIIRYGNQQSLSWAEQHFFKSSIFILDWICTKKPGTSALIQA
                     LRLHLILLLATGWEIPRLIAVCDFFIDGWLPRLYISGADIEAQKIFWVKEFETSFDRTK
                     AVILPASKVFWEELTTGTANQKVQDLLKTNIMILQNYQQADFKETKFIEIMTSLMHMNN
                     NRLGISNHEEAYGMYCTRQCLDFIANS"
     gene            13662..15614
                     /locus_tag="AY601_RS24530"
                     /old_locus_tag="AY601_4950"
     CDS             13662..15614
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="AY601_RS24530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_4950"
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_068406535.1"
                     /sec_met_domain="LANC_like (E-value: 2.9e-52, bitscore:
                     175.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLFTQLQTRRIQKQLAQLKSDLLASSRRDETGVYWQSPFYETID
                     KFSFQTTFDIFNGNSGIALFYIGLFELSGEPKDLKMAEDIMHKVLKEEAVLKPRSFGFY
                     TGITGVIYVCIKLYAHTNEEKYLRRASYLLLDNQENIVNNTAKADLLSGYCGSLFVITL
                     LYHHLRTKKLLAIVHQLIDRVINEARISEAGLKWDYNQSKSSFDSLAGFSHGASGIACV
                     LMQVGNYFKHDGLIYLAEQVLAYEMQYFDPVTGNWLDLRLGKFRLNLPDAHRWELNVFI
                     PEMNKVNSWAHGAGGIGLARLMAYELTGKEIYLQQCQLVMKRCLKDLEKMHRTDFTLCS
                     GYMGMLPFLSRFAGLLQKNYAESILSVVDQAGVQYARKRSYNTYISANQFDYGLLSGKS
                     GVGYILIQLLNKEMDSVVYPVLPPNKKLPPVITSYSQFAVKQRIFSTYYAKTIYLLEQF
                     EPGSMLKMQAEDFNGFEEWLYQRIRSLPALEESGITALFDFEHQLAIRWKLHKGYLCYK
                     KKNEFIQDQAKQLSLVTAEELCNLSFKLNDHVGFYPLSTKLKNVMGLPETYQAALFMSD
                     EHGVKAIYIGQLSSLILSGLAEQAVTGQELISLILENFSGNAKLKPETTVLRERILLQM
                     RSLIISGMIGLKEEV"
     gene            complement(15671..15862)
                     /locus_tag="AY601_RS24535"
                     /old_locus_tag="AY601_4951"
     CDS             complement(15671..15862)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038180.1"
                     /locus_tag="AY601_RS24535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_4951"
                     /product="pinensin family lanthipeptide"
                     /protein_id="WP_041882676.1"
                     /transl_table=11
                     /translation="MKNQSEKIKLNLEDLQLESFVTSIDSEVAMRLSGGLGNVSEPTHT
                     EPTDDHHTPAIKCTTVIC"
     misc_feature    16000..16016
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.88"
                     /tool="antismash"
     gene            complement(16360..17592)
                     /locus_tag="AY601_RS24540"
                     /old_locus_tag="AY601_4952"
     CDS             complement(16360..17592)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015863.4"
                     /locus_tag="AY601_RS24540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_4952"
                     /product="PepSY-associated TM helix domain-containing
                     protein"
                     /protein_id="WP_068406540.1"
                     /transl_table=11
                     /translation="MTLKKINAWLHLWLGLASGLIVFIVSITGCIYVFEKEIRSLYQPW
                     QFVQPQEKSFLLPTQLIAHAKPELGKLKPTSINYGQKNEAATVNSLNRKKGTSLVIYMN
                     PYTAEIIHIDRKSKRSNVDFFRFILNGHRTLWMGKTGSKVIGVGVLIFVCLLISGIVLW
                     WPKKWIKSIKDQSFKIKWSGSFKRVNYDLHKVAGFYVFLVLLLISLTGLVYSYKWYSKS
                     LYWVTSGGKSLEAKPRPLSDTTTNAVFQPKNIDKIYSKLATTSQAAGMFITLPAKSSDA
                     IGFIVYLKAGTFYKADRYAFDQYTMKQFAGNSPLLGKYEDASIPDKIRRMNYDLHVGSV
                     MGLPTKIIAFLASLISASLPITGFLVWYGKKFKKKKGKKPLVQEKMVLKKKISPWELKK
                     VRTAAMQEPVI"
     gene            17939..19066
                     /locus_tag="AY601_RS24545"
                     /old_locus_tag="AY601_4953"
     CDS             17939..19066
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008244180.1"
                     /locus_tag="AY601_RS24545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_4953"
                     /product="porin"
                     /protein_id="WP_068406543.1"
                     /transl_table=11
                     /translation="MNKFLILVVLSLTGVFQIRAQEPVKQDSTAKGKITMRGLFQARYL
                     FSGNKNIDLNGLHHLDGKAVYNDFDIKRARLQFTSKISDRTDVVLLLNLADFKTDPKNK
                     VLENAYITYRLDNFINLKMGQFRPAFGLEDMYPVDVIKSMDYSNQYTAFGNNGWQSFQI
                     GASIYGATHGEIPVKYELSVINGNNRNQLMDNDNGKHFSTRVELGLQKSLKIKLGLNGG
                     LATVLGSNVYAAGVDLSGVVPLGKKWSLEIETEFKQGNNHTFYYGLDSAKRVGGVDNYQ
                     MHGLYFLPNLRYAINYHRLSSLEFSCRYENFNNDFKHAANNPRQTWTPMVSAEFLKAYS
                     ARIQFGVNIDRYKRNIPGTIQYNNEMFIVQVQSRL"
     gene            19081..20550
                     /locus_tag="AY601_RS24550"
                     /old_locus_tag="AY601_4954"
     CDS             19081..20550
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003001370.1"
                     /locus_tag="AY601_RS24550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_4954"
                     /product="anion permease"
                     /protein_id="WP_068406546.1"
                     /transl_table=11
                     /translation="MKSTATTAAAAPPKKEIQPIPLLITVVFGLAIWFIPAPEGVKPEA
                     WHLLAIFLATIVGIILKAASMGTLCMMAIALVAMTGVLAPGNPGKSITLALRSFGDKVI
                     WLIGISFFIARGFIKTGLGSRIAYIFIKLFGKSSLGLAYSLGAADLILAPAIPSNTARG
                     GGIIYPIMKSMAMSLGSMPDKAETHRKVGAYLTLNSYYMNLIASAMFLTGTASNPMCQK
                     FAADMGIHISWMSWFWAAIVPGLASVIIIPFLLYKIFPPELKKTTEAPAMAIAKLKEMG
                     EITKNEWLMLLAFVILLVLWVTGDLFKIDATTTAFIGLSILLLTQVLTWEDVKAEKGAW
                     DTIVWFATLVMMAGSLNELGFIPWFGHLIQTLLLGMSWTLAFPIIIVVYFLSHYLFASA
                     TAHVAAMYAALLAVGIAMGVPPLLLALMLGFTGSLFGTITHYAHGPAPVYFGSGYVDVK
                     QWWIMGLIVGIALLAIWMGLGGLWWKVTGVY"
     gene            20561..21244
                     /locus_tag="AY601_RS24555"
                     /old_locus_tag="AY601_4955"
     CDS             20561..21244
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008510086.1"
                     /locus_tag="AY601_RS24555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_4955"
                     /product="succinate dehydrogenase cytochrome b subunit"
                     /protein_id="WP_068406549.1"
                     /transl_table=11
                     /translation="MKLTFLKSTLSRKNLMALTGLFLCFFLVIHLLGNLQLLLPADRAA
                     ERFNHYSDLLSGNIFIKMISYVLYLSLIAHAVDALIITVRNKQTATKYAYDNRKQASKW
                     YSRNMGILGTILLIFLVIHFKDFWYVYKFGTVPFDRNGNKDLYVVVVHAFKSWWYVLLY
                     VLSMFALGFHLLHGFKSAVRTLGLYHPGYAALVQTFGTVYSYAITIGFAVIPVYVHLTQ
                     FGLWN"
     gene            21235..23151
                     /locus_tag="AY601_RS24560"
                     /old_locus_tag="AY601_4956"
     CDS             21235..23151
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004079.1"
                     /locus_tag="AY601_RS24560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_4956"
                     /product="fumarate reductase/succinate dehydrogenase
                     flavoprotein subunit"
                     /protein_id="WP_068406551.1"
                     /transl_table=11
                     /translation="MELDAKIPAGPLETKWSQYKAQAKLVNPANRKKLPVIVVGTGLAG
                     ASAAASLAEQGYPVTSFCFQDSARRAHSVAAQGGVNAAKNYQNDGDSVYRMFYDTLKGG
                     DFRAREANVYRLAECSLNLIDQAVAQGVPFAREYGGYLSNRSFGGVQVSRTFYARGQTG
                     QQLLLGAYQALMRQVSLGKVNLYSRHEMLDLVVIEGKAKGIIARNLDTGLIERFAAEAV
                     VIATGGFGKIYYLSTLAMGCNGSAIWRAHKRGALMACPSWTQIHPTSLPQSGDYQSKLT
                     LMSESLRNDGRIWVPQLPDEQRAANDIPEQERDYYLERRYPSFGNLAPRDISSRAAKER
                     IDAGFGVGAQRNAVYLDFSKAIKEQGKEKIKEKYGNLFSMYKKITADDAYAAPMKISPA
                     AHFSMGGLWVDYELMTTIPGLFAIGEANFADHGANRLGANSLLQACVDGYFILPYTLAN
                     YLSGELKKEKITTDHPEFDRTEKEVVTQLTGLCELKGTKTADYFHKKLGKLLYDKCGLS
                     RSAEGLTAAIEGIKILRTAFYKDLIVPGTAGEINSELEKAGRVADYLEIAELMCHDALS
                     REESCGAHFREEYQTADGEALRDDENYCYVSAWEWRGKNSLPVLHPEHLKFEFIKLSVR
                     SYS"
     gene            23157..23903
                     /locus_tag="AY601_RS24565"
                     /old_locus_tag="AY601_4957"
     CDS             23157..23903
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015809067.1"
                     /locus_tag="AY601_RS24565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_4957"
                     /product="succinate dehydrogenase/fumarate reductase
                     iron-sulfur subunit"
                     /protein_id="WP_068406553.1"
                     /transl_table=11
                     /translation="MKIHLKIWRQKDAKAKGKLVDYMLDQVDHHMSFLEMMDTLNEQLI
                     LKGEMPVEFDHDCREGICGTCGMMINGQAHGPVPGLTACQLHMREFEDGATIYVEPFRA
                     TAFPVKRDLKVDRSAFDRIIQAGGFITANTGQPVEANTLLITHETAESAFDSAACIGCG
                     ACVATCKNSSAALFTSAKVSHLAKIPQGEKEAAKRVLKMVSRMDEEGFGHCSNTEACEV
                     ECPQGISVLNIARMNWEYTKANLLKD"
ORIGIN
        1 gaaccattga acaagtgaaa agcctgacac tggcagcaga aactcctttg cagaaaatag
       61 agtacgcctt gcatccatgg gtagctttca tcattatgcc gcttttcgcg ctcgctaatg
      121 caggtataat tataggggca gacttcttct ctgctttgat gaatccggtg agtatcgggg
      181 tgatatcggg cttgatcata ggtaagtttg tgggggtact tttgttcacc tggttaatgg
      241 tgaaaacagg actggcacaa ttaccggatc aggcgaactg gaaacatatt acaggcgttg
      301 cattactggc cggggtaggt tttacaatgt cactgtttat cagtaacctg gcattcgaac
      361 aaccagaatt cattgaacag gctaaatacg gtatcctaat tgcctcgctc attgcgggta
      421 tatcagggat aacgctgttg aaaagtttta aaaaagctta agcaatccat cacttctgtc
      481 agctcaccat aattttacct gctaaatatg cagaattgaa acaagctgat cactattttg
      541 ttttatcact aaaacctgga aattatgatt attacagaaa ataatacacc ctacaataac
      601 gaagaagagg aagatgacca attaagtcag caagacgtgc aatctgatgg aatagatgct
      661 attcctccct cagaaacaga taccctggct accgaaattg aaaatttaaa acaagcagat
      721 aaatcttcag aagctgctta tactttagat gcggatcggg gaatcgctcc gaaaaaagaa
      781 gaagaataag gtttcttacc ctcataaaat caggctgtct ccaatgaggc agccttttat
      841 tgttaagaat atttatatat ttcctgcaga ttcaaatctc agaaacaaca aatttcatgt
      901 ataacaaata taaagtgctg gcattcgggc tggctattac ccttgcttcc tgtcaaaata
      961 ataacaaaga aacaaaagca gttgctaccg ctgcagatgc tacctcaacc caggttccca
     1021 aaaatctgac ttataaagtt gctggtacat taccacatga tactgctgct tatactgaag
     1081 gatttgaact tcatggcggg aaaatttacg aggggaccgg aacctatgag aattcatatg
     1141 ttgctgtttc agataccagc tctggtcagt tggagaaaaa gtttccactg aaagacaaaa
     1201 gcatttatgg ggaagggatt tctatattgg gcaatcagct ttttcagctc acttatcaaa
     1261 atcatatcgc ttatgtctat gacctgaaag atctgaccaa accaacaggg actttcaagt
     1321 ggcctcagga aggttgggga atgactaatg atggtaaaaa cctttacgtg agcgtaggaa
     1381 gctctattat ctataaactt gacccaaaaa gctttgctgt tgtcgggcaa atacaagtca
     1441 ctgataactt aggaacagta gatcagctga atgaactgga atatgtagat ggatttcttt
     1501 acatcaatca atggcaaact acaaaaatat taaaggtaga tgtgtccagc ggaaaggtgg
     1561 ttggaactat tgattgcttc gggctgttgt caaattatgc gcctgattat acgcctaaat
     1621 ctgaagacag tgtactgaat ggcattgcct gggacaaaac acatcaatta ttgtatgtaa
     1681 caggtaaaaa ctggccgctg attttcaagc tgaggttaga ctaacaatca gcaatacctt
     1741 aattcaaaca acggtagacc tggcgatgcg cggaagagcc atcagttttt atgcgatggc
     1801 ttttttcgga atccggccgt tttttatgga ttgatgaagc taaaaaaata aaagccgggc
     1861 aggaggtttt atcctcccgc ccggcttcct ttttatatcg tttccaggta taacttttgc
     1921 aaatcattcg cagaaatatc ctttgcattc aacgtgtgaa tgagcgatcc ctggcgcata
     1981 attccaatcc ttgtccctac atttaccgca ttaaaaatat catgggtggc cataaacaca
     2041 gttcttccat ccttggaaag ctgtttgaca atttcactga attcatgggt tgcttttgga
     2101 tcaagcccgc tggttggctc atccattaag atcacttctg catttttagc aacagcaatg
     2161 gcgatcccta ctttctggcg catcccctta ctgtaatttc caacccgttt atggaaagct
     2221 tccggctgta aacctgcttg taataaatac ttttccagtt cttctttttt atagttgaat
     2281 ccggctatcc ggctaaaaaa atcaagattc tctaaactgg tcaggtttgc atacagcatg
     2341 acaatctccg ggatataggc cagaaatttt ttagtctcag gctggtctgg gctcaccaaa
     2401 accccattaa ccagtgcctt tccggatgaa gctcctgtaa aacctaagaa taaattaatc
     2461 gttgtggttt tacctgcacc gttctggcct aataaacaaa acacttctcc aggttcaacg
     2521 ttcagattta agccattaag tgctacctga tccccatatt ttttagtcag ttctattgct
     2581 tgtaacatgc tgtttataat ttaaaacttg attcctatag aaacttttac attaaacgga
     2641 tcaccatcga tatagtagaa attacggccg tcataaggat aacccgtaat caaatcacca
     2701 gatgacatgt aacgtttacc agtcaggtta tctgcgatta agcgaaagaa atatttatcc
     2761 tgcacataac tcagtcctgc atcatattta gtaaaatcag ggatatactg atttttctct
     2821 gaagtactgc gtttgatcat cgtggtctgc cctaaactca ggttcagact tgctttgttt
     2881 ctcaatggaa aactgtactg tacccaggta ttaaagatct gctgcggggt ttgcggaagt
     2941 tctttgccca gtaattccgg atcctcatct ttagtgatgg ttgatttcac ataggtgtag
     3001 ttcgtggaaa tagaaagctg atcagtgatg tttccaatca catcaacctc aattccgtta
     3061 cttgtgacct ggcctgcagg ttttacaaac ccggcattga tcagatctgt taccggaacg
     3121 tttgatttta aagtatgaaa cccatttaaa gttgtgtata agcgggagtt gaaccagttt
     3181 cttttaatgc ccagttccat atccttacct ttttgagggt cgatggcttc tgttccggtt
     3241 atttcttttg ttgtgggatc aacaatcgca cgctgatagc tttgagggac aaaagactgg
     3301 tcatacaaga agaagattga cgtagctgga ttaaccaggt aagttaacgc agcacgtggg
     3361 gaaagtgctt tttgatcata attattggtt ttaacgacac ctctggcatt cgttgtttct
     3421 ttgtcgttct tataccaggt atatcttgca ccaagcgtta atagaagctt tttctgcaat
     3481 tgaatattgt cataaataaa agctgatttt ataaaagtat tgttgtttgt cctgttaatc
     3541 ctggtaatct gattgactgt ctctgctctt gccgtattta ttgtcccgga tttgttgtag
     3601 tctgattcta tctttccgtt attcagggat aaagaatccc tgctgttggt ataatcagcc
     3661 ccaattaaca attgatgttg aatacctccg gttttaagct gaccgtttgc aaatagttga
     3721 gtagagaagg ttttgcctgc acccatcgat aagctggctc tgcgtttcgt atttccattg
     3781 gcatcaaaat tcaccatact ccctttggaa gtcatattcc agtttttata aggtgatgat
     3841 aaataagaag attgtgaagt aacctgccag ttatcattga atttatggac cgcatagatt
     3901 cttgcagtct cattttgtgt ataacttgtg ggtaaactac gctctgagct atagttggtg
     3961 ctgatcgggc cttttaaaat gtcttgttcg ctgcggactt tgacaattgc agaaccattt
     4021 tgaacttcgc ctctgataaa atcatactct gccagcacat aagtatttgg actgaaatta
     4081 tactgtataa ccggggcgac cacatattta ttggttttga gatcattcag gtaagaatct
     4141 ttatgctgat aagccgtatt aaagcggtaa gagaatcctt ttttctgaac ctcagaacca
     4201 atatctgcgg ctatacggta caggttgaaa cttcctgctg tttgtacgat atttaacatt
     4261 ttatgccccg gagttttggt caggatatta atggacccgc ccggttcacc cacagaattc
     4321 aggaagccgg cagggccctt aacaaattct acattctcta tcagcgcatc atcgtcaata
     4381 gaagcgccat aactaaaacg gcgtgacatt ccattcagtg tagtatacgc tgcgaaaccg
     4441 cggatttgtg cgacagcaga attatcaaat ggggtactgt tgtagccgaa ataaacaccg
     4501 ctggcattac gcgccgcatc tttgagttcc agtgcacctt gttgttgcaa taaacctgtc
     4561 gatatgctga tgatgttctg agggatctga attaacggct gttgaagctt taagctattg
     4621 gaaagcgtat cggttttaat cctgaccttt tttttactgg ttacgttaat ctgttcgagt
     4681 ttattgagct gacccgtggt atcggttaac ttttttggtt gttgagcata tagcaagttt
     4741 ggcagaacgc tcaaactaaa gataaataag taaaagattt ttttcatttg gtgtggcaat
     4801 tagtggagtt gttaattagt atgttgactt gttttttctt ttgaaggcaa tctgattggc
     4861 aatctggcgg gcaatcagta aggtcagtaa gatggccagc cagatagata aggtattgac
     4921 cagaatacga gaggttctgg tttgatcttt tgcaggatga aacgcaggca ggttctggac
     4981 ttcgatcagg ctgagtttct tgttagacaa cagataaccg ttgatgagtt ttacccactg
     5041 gttttgaaat aggctggttt gattttgata atacagatag tcactgagtc cggtttgtgc
     5101 agttgcattc agtagcgcct gcatttgagc tactggatta agccaggcca tttgacttag
     5161 ccaggcatta tgctttgcag cggcagtagt atattccatc acatttttgt tcatccgcct
     5221 gcctagcagg tcataataag ccacgaatct tttattgcca tagcgcgcag tatctccgtc
     5281 agttttcaga ctaaggtatt gcggattgtt ttgatagaat tccttcaata attgcgggat
     5341 cggcatttcc caggtatggg tcatcgtttg ccgctgatta gatacgagtt cagtacgcag
     5401 cggcatcgga tatttaagtc ctgcaaattt gttggtgatc gctggtaaga tcaaggtaag
     5461 cagcaaccag atgccgatta atatcaaagc attgagctgt gaagatttgc gaaggatgat
     5521 catcagccag cagactgcga accaaaatat caggtaagta ttggtcacca ggatccataa
     5581 aagaacatca ggcagatgca gggcagcagc agctgggtgg ataaagaaac caatgatgct
     5641 gagcatattg gttagcaggc tgattaatag cagccggaaa aggattttat gccttagaat
     5701 ccggttgatt gcgccacttt gaacagcgag cagacggtca gtttgctgct cggcttctct
     5761 ggaaaaaaga tcgtaactca ggatgatgat caagagtgga aacaaataga tcagcacaaa
     5821 agaaaaatcg aaattacccg acgccagttt ctccggatta gcgatttctg cattgggtgg
     5881 cgttaaaata tcacgtttac tgctaatgat atcaaaatat ggaagtaaat cacgctgacc
     5941 aatagccagc gcagccaatg cttgtggcgg attagttgca ataggtggag ctttgaattc
     6001 cacgaccttt ggcaaacctg cctgctgggc cagaattttt ccttgtgcag tagtggtatc
     6061 tgtatgaaac ctgctgatta gttcctggag attcgcttgc tgattgttag tcagcgtatc
     6121 cagcccggtt aattgctttt gtacaaaact ctggccgttg tacaggctgt atacgctcat
     6181 caacaggaaa aatagcagta acaatagttg aacgggctga cgtaagaatt gccgccactc
     6241 gaaacggaaa attaaaagga ataactgcat atttattgca atgaaggttt ggtaatgaag
     6301 tataaagcca tggaaagcag cgctatccat gcgcaaagtg aacctaatgc caatcgttgt
     6361 aaatacaagg tttccagcaa ggttggcgcc tgataactga aatctttgag ttgcagaaaa
     6421 aaccgggggc ttgcctggta actttcattc ggttttacag gatggctggc caattgaaga
     6481 ttcaatttgc ggatcaggtt attgcggtat tcttttgcct gcaggaagaa gctttggtgg
     6541 tggtagaaat cggtaccaga catcgccata gaaaggcgct ttaaactcat aaagggatct
     6601 gccagccctg cataattcag agaagactgc tgctgattga acgtgtttgc cagcgctgta
     6661 taataatgat cgaatacctt gttctggtaa tcttcattgt attgcagcat taaaccgtca
     6721 gcattaaccg gaagctgcgc tgcgctgtct gccccgtatt tttttaataa agctgcatag
     6781 tgtttctctg ccctttcgtg ataaggtgca tctccgttaa tcccctttaa aaatccttgt
     6841 ttaacgttat tattgaaagc tgcgcgggag attaaaggat attgatccgc tgcatgacca
     6901 gctgctattt tcggaaagag gatactgctg aatagccata ctgttaaaac agtaagtgtt
     6961 gccgttcttg aagtcccgct aagtgcagat acgatgactc cggttaaggt gaccagcaaa
     7021 taaaaaagca ggtaaccaca aagcagtatt aagaaccggc ccaataaagc aatgccagaa
     7081 ggggagcaaa ggaccacaaa aaacaggact acaaaaattg gcatgaccag gaaaaccacc
     7141 aataaataat ttgaccaaac ctttccccaa gccaattgtg aaggctttat cccttgggcc
     7201 atcagcattt taaaagtgcc ggattctttt tcataagtca gtgcagaaga actgataaag
     7261 agcagcagca agggaatcag catttgcata atcaaagcga gggtgaactg gccgaaccgc
     7321 atcaaggcgt cattacgttc ggcattgcta taatctacct catgctgtac atgggcttct
     7381 acacgataag tagttccgga ataatcatta agtcctggat caaaggcact taaaagattt
     7441 aaaggtttaa aaagataggt gccgaaatgt gcggcctcat gtggattgtt atgttgggct
     7501 tcccactgct gacggaattt tttgttggat agttcccggc tttgctgatc gttttgatac
     7561 tgcaaaacag ttaacagccc gcttgcaatg aacaaagtat aaataatgat agccaatgtg
     7621 ctcattattt tatcgcggaa agctaacctg agttctttcc agattagagt acgtaaagga
     7681 gtgtattgga gtggagacat ttattaatta ttaattgcat caaagttgca ttatatttat
     7741 aatatttgca acagtgttgt atttaagaat cgtttagcta tgtttcaact tttctcttct
     7801 ggcaggaaat ttccgtttta taaacaacca gatgcaatgg attgcggacc ggtttgtctt
     7861 aaaataatct cggcatatta cgggaaaact tttccaattg cttatttcag aaagctttgc
     7921 agtataggta agcaggggac tacgatgacg agtatgctgg aagcagcagg tttactgggc
     7981 ttcaaaacac tcgcagcaga aatcccttat gaacaattgt tgaatagggt ccggttacct
     8041 tgtattcttc attgggaaaa ggaacattat gtggttttat accgcatgac cagcaaatat
     8101 gcctacctgg ctgatcccgc acttagtgga aaagttaagg tgcgaaagga agattttatc
     8161 cgctcctggc aaattaaaga aggcagcact attggcaggg ctttattgct ggaaactacg
     8221 ccggctttcc aggaaaaaca aagtattgct gatcattcgg cttccttatg gtctttaatg
     8281 ccttacctca aattacaccg taaaagttta atccctgttg gtatcagcct tttgctggcc
     8341 tgcggtttct ctctgattat tccattttta acccagctga ttgtggataa agggatccag
     8401 gggaaaaata caaatttgct ttttctgatc tgtatcggac agttgatgtt gttttccgga
     8461 aggatgctga tggactttct ccgtgcaagg ttgcttttca ggttaggcgc caggaccagt
     8521 atcgttttat tgaaagagtt tctggccaag ctgatgcaat tgcctttttc attttttgat
     8581 aaccggcaag caggtgataa tatgcaacgc gtaaatgata accagcgggt cgaggaattt
     8641 ctgacgaatt ccctgattag ttttattctt tcggcaatta cgctggtcgt attgggcggg
     8701 gtactgtgtt attacaattg gcaaatcttt ttaatcttcc tgattggtgc agtaatcagt
     8761 gtgacctggt ctaattcttt ccagcaaaaa agaaaggtca ttgaccagaa gaaatttaaa
     8821 gtcctttctg ctaatcagca gcttttactg gagatttttt atgcgatgca ggaaattaaa
     8881 cttacaggca gtgaacagga aaagcaggag ttatgggaag gcttgcaaga tcagtcttat
     8941 gggcttaaac tggaagcgct gcaactggat cagttgatgc aggggattgg ttacttcatt
     9001 aatgaagtca aaaatgtgtt gattacttat gcggcagcga tgctggtgat caatgatcag
     9061 gttaccctgg gcgggatgct ggccattact tatatctgtg gtcaacttaa cacgcctatt
     9121 acacagctcg ttgagtttgc gcgggtctct cagaatacaa agtttagttt acagcggatg
     9181 gcagaagtgc atcaggaagc ggaagaagat tttgaagtcg gctaccggga tatgaccagc
     9241 gctcctgaaa atatcgaact gaaacaggtg agttttcaat atggaaacag ccatgcacca
     9301 ttcgtcttaa aaaatctgga tctgttgatt cctgcgggta aagttacggc tatcgtaggg
     9361 atgagcggaa gcggcaagac tactttaatt aaactgttat tgaagtttta ccaggtgagc
     9421 aaaggctcgg ttacgattgg taatctttcc gtggatcagg tacatgctaa acagtggaga
     9481 gccgcttgcg gcgtagtgat gcaggatggt tatgttttca tggacactat cgcgaataat
     9541 atttttgctg gctcagtggt caaggataaa gaacgtcttt atgaagtttc caaactggcc
     9601 aatatgcatg atttctttat ggccatgcca tttggctatg atacggtagt tggcaaagat
     9661 ggatatggct tgagtgaggg acaaaaacaa aggctcttaa ttgccaggct gatctataga
     9721 aatccggcct atatattcct ggatgaagca acgaattcgc tggatgcaca taatgagttg
     9781 tccatcgtca acaacctgaa taatttcttt accgggaaaa cagtgctgat tgttgcgcat
     9841 cggttgagta ccgtaaaaaa tgcggatcag atcgttgtat tgcatcaggg ggagctggtg
     9901 gaaaaaggaa cacatcagga gttgattgcc aggaaaggga attattacca actcatcaaa
     9961 aatcaactgg agctaagtaa ataacctaaa caactaacac atgagcattg agatatttcc
    10021 acactcttta gtaagatatg cagggatgaa ttatcaggtt tttgattcgt ttaaactcaa
    10081 aggatcgaag gggatactgc aaaaagatca ccagatgaaa gcggcaaaaa caaagcttaa
    10141 agcattgatt tgtgatggac tatttgagct gattacgctt cagaccgatg atttgctccg
    10201 gcagcagctg attaatctta agaggcaggt ttttaatgat aaaaaagtaa atccgcaaaa
    10261 actggaggag ttgctgggcc tgtttccagc agacctgacg ttggactttc ataactacct
    10321 acaggtaagc cagaatatgg aaactttcca tcagaccaat actttgaatt atcagcaact
    10381 gctgatggag caaagtaaga aacttcagga actggctatg gatccgcatt tgcaaaacgg
    10441 actgcttttg tcaagtccgg ttttactgga gcaattaccc ggctatttgc aaaaagaacc
    10501 agcttccttc cggcaaaagg aattgcgaat agagttcagt ttgctgcgtt acttaaccag
    10561 gatgtgtttt aagacttcgc cattcagcac ttttacctat accgggatca tgcagttagc
    10621 ggataacggg gctgtaatcc cttcgcccat ggctaaagct gttaaaaata gtctccggct
    10681 taacaatgca ttatttgaat acctgaaatc tatcctgatc catcatccgg gggtgaatga
    10741 attgctgact gtaaaactta ataaaacggc tactatcaag gccggtaaaa tccaattcct
    10801 ggttaatttt aataatattg aatcttttca gctattaccg gcttcgggtt tacaattact
    10861 tgttttcaat tattttaatt cggctcagga atcaataaat attaaagaat tggcaaatta
    10921 tatggcttat gctgtggagg aagccaatta tacgtcaatt aaaaactatc ttcttaaact
    10981 ggttgctgcg ggtttactgg aagttggcat ggaaacttct ggaattgatc cgcaatggag
    11041 tctaaaatta ttgaatttct ttaccaaatt ggagagtagc gaaccggctg ttcttcaaat
    11101 catttatctg tttaagcagt tacagcaata tcaactggct tatgcgaagg gagatactgc
    11161 aaaacgaaaa ttgatcctgg cttatgcaga aaaaactgta gcagctgttt ttcagaaatt
    11221 acaggccgag gcaggtttgc cgttaagcag ggatacgaca aaagaagtag atgaccagtc
    11281 aaaaaaacaa gctgtcaacg gggtttttga aactcagaat tttataccac atcatttctc
    11341 tggcagacaa ctattttatg aagattgtta tacgcctgaa ctggaaattc tggaagatgg
    11401 ctgtcttcag gattttgcgg caaaggccga tcagctttta aatcacttgc ttccgcttga
    11461 tttactaaaa actgagcgcg aaaaaatgag cagtttcttt ctggaacatt atcctgctca
    11521 ggcacaggtt aaggtaattg atttttacca ggcttattat ttttatgtta aaaaacctga
    11581 aaaggagaaa tcggcaaagc tagggccggc tatacctgat cccagtgaat gggagaaaac
    11641 gatcagtgaa aaactagcct tgattaccca gcataaacca aatatcctga acctgggaaa
    11701 tgattttttt cctgaagcct tatcaacaga agctcctgtt gcagcagttc agtattcaag
    11761 ggggcttttc gttcaatttt ataaagggaa attacagcag gaagcggaac ataaggaatg
    11821 tttttttgga gtgatcaata ctgtgctgcc gggaatgggg aaggtaagtg gccgcttttt
    11881 gcccttattt acacccgata tgactacaga ttttgtcaaa tataatacac agcttcatcc
    11941 tgaagtgctc aaagtagagc tcaatgatgc ttcaagtttt aatgcgaata ttcatccttc
    12001 tttacttact cgcgaacttg ctttgcccgg tggaaataaa agttatccgg aaaaacaaca
    12061 gcttcccgta gatgggttaa cagtaagttt tgaacagcag acaagtgctt taaagctaaa
    12121 ctatcagcag gagcaggttt ttacctatga tttatgtctg gaatcttttt ataaccgttc
    12181 caacctgtac cagcttctgg ctcattttaa ccaggacacc aagctttctt tacagccatt
    12241 tattaacctg gtggacgcct gttatctgga tgttgaggag caagaacagg aaattgagtc
    12301 tctgccaaga attacctacg aaaattcagt tattctcagg agaaggacct ggcgtataaa
    12361 aacagcgtcg atacctgtgc agcaggcagg agaaaatgct tatgcttatt ttatcaggat
    12421 caatacctgg agggctcagc acggaatccc tgtaaccttc tttttatttc tgagaaaaag
    12481 atcttttgtc attaaaccag ctgctcagcc aaatggcaaa aaggaaggac ttagtgatga
    12541 ttataaacct cagtttatat cttttgaaca gcctttatta gttgaaatgt ttaagcgttt
    12601 actggccagg gcagggactc atgtgatcgt ggaagaaatg ctgcctttga ctaatgcggc
    12661 tacagaccaa gcaggttacg ttgagccagt taaagaatat ttgttgcaat ggtataaata
    12721 tgaatgatgg aaaggaaaga taaagctgtt cagtatcaat ggtttgccgc ttacctgttt
    12781 tatcccggag atctggattt gatgttgcgg gaattagtcg cgccatttat ccgggaattc
    12841 ttccctgatg agcagacgga tgcgcaatac ttctttattc gttactggga aaatggaagt
    12901 catatcaggc tcaggatcaa tgttgagtat gctttacacc aggttttagc taaagcattg
    12961 gaacaaaaaa caaatgattt ttttagtcag tacccggctg tcaggaaatt aaaagattct
    13021 ttgaatcagc ctgtttctca gcctttagct gctgaccacg cgatacagtt ttctgtttat
    13081 gagcccgaaa tcatacgtta tggaaatcag caaagtttga gctgggccga acagcatttt
    13141 tttaagtctt caatttttat tctggactgg atctgtacca aaaaaccggg aacttctgct
    13201 ttaatacaag ctttgcggtt acacctgatt ttattgctgg ccactggttg ggaaattccc
    13261 aggctgattg cagtttgtga tttttttatt gatggatggc tgcctcgttt gtatatttcg
    13321 ggagcggata tcgaagctca gaaaatattt tgggtaaaag aatttgagac ttcgtttgac
    13381 cggacaaaag cggttatttt accggcttca aaagtctttt gggaagaact gactactggg
    13441 acggcaaatc aaaaagtaca agatttgcta aagacaaata tcatgatcct gcaaaattat
    13501 cagcaggcag attttaagga aaccaaattc attgaaatca tgacgagtct gatgcatatg
    13561 aataacaatc gcctggggat aagtaatcat gaagaagcct atggaatgta ttgtacacgc
    13621 caatgccttg attttatagc caattcttaa ttcaaaaata tatgcctctg tttacccaac
    13681 tgcaaactcg aagaattcaa aagcaattag cacagctcaa aagtgattta ctggcttcct
    13741 ccagaagaga tgaaactggt gtatattggc agagtccttt ttatgagact attgacaagt
    13801 tctcttttca aacgacattt gatattttta acggaaatag tggtattgct ttattctata
    13861 tcggtctttt tgaactttct ggtgagccga aagatttaaa aatggcagaa gatattatgc
    13921 ataaagtgct gaaggaggaa gctgtattaa agccacgttc ttttggtttt tatacgggca
    13981 taacgggggt gatttatgtt tgtattaaat tatatgcgca tactaatgag gagaaatatc
    14041 tgcggcgtgc ctcgtattta ttgctggata atcaggaaaa tattgtcaat aatacggcta
    14101 aagctgactt gttaagcggt tattgtggaa gtttattcgt aatcacttta ctttatcatc
    14161 atttaaggac taaaaaactg ctggcaattg ttcatcagtt aattgatcgg gtgatcaacg
    14221 aggcaaggat ttccgaagca gggctgaaat gggattataa ccaatcgaag tcttcttttg
    14281 atagtttggc tggattctct catggggcat cagggattgc ttgtgtttta atgcaggtag
    14341 gcaattattt taagcatgat ggcttgattt atcttgctga acaagtactg gcttatgaaa
    14401 tgcaatattt tgatcctgtt actggaaatt ggctggacct gagattgggt aaattcaggc
    14461 tgaatttgcc ggatgcacac cgctgggagc tgaatgtgtt tataccggaa atgaataagg
    14521 taaattcctg ggcacatggt gctggtggaa ttgggcttgc cagattaatg gcttatgaac
    14581 taacggggaa ggaaatttat ttgcagcagt gtcagttggt gatgaaaaga tgtttaaagg
    14641 atcttgaaaa gatgcaccgt accgatttta cgctctgcag tgggtatatg ggaatgctgc
    14701 cttttttatc caggtttgcc ggcctgttgc agaagaatta tgccgaatca attttatcag
    14761 tagttgatca ggctggtgtt cagtatgcgc gcaaacggag ctacaatact tatatttctg
    14821 ctaatcagtt tgattatggt ttgctatctg gcaaatctgg ggttggttat atcttaatac
    14881 aattgctgaa taaagaaatg gacagcgtgg tttaccccgt tttgcctccg aataaaaaac
    14941 tgccgccagt tataaccagt tatagtcagt ttgcggtcaa acagcggatt ttctctacct
    15001 attatgctaa aacaatttat cttctggaac agtttgagcc tggctctatg cttaaaatgc
    15061 aagctgaaga ttttaatggg tttgaggaat ggctttatca aagaataaga agtttaccag
    15121 cacttgaaga gtcaggaatt acggcattat ttgattttga acatcagctg gccatcaggt
    15181 ggaagttaca taaaggttat ttatgctata aaaagaagaa tgaatttata caggatcagg
    15241 cgaagcaatt gtctttagta actgctgaag aattgtgcaa cttatctttc aaattaaatg
    15301 accatgtcgg tttttatccg ctgagtacta aacttaaaaa tgtgatggga ttaccggaaa
    15361 cttatcaggc cgcattattt atgtctgatg aacatggggt gaaagctatc tacataggtc
    15421 agttgagttc gttgattctg agtggtcttg ctgaacaggc tgtgaccgga caagaactga
    15481 tcagcttaat tttagaaaac ttttcgggga atgcgaagct gaagccggaa actaccgtat
    15541 tgcgggagag gattttatta caaatgagat cattgatcat tagtggaatg atcggcttaa
    15601 aagaagaagt ataaaagagg accggaagcc ggccctcttt tttgaactct ttgtactaaa
    15661 ttaacttaaa ctagcaaata actgtagtac acttaatggc aggtgtatgg tggtcatctg
    15721 ttggctcagt atgggttggt tctgatacat tacccaaacc gcctgataaa cgcatggcaa
    15781 cttcactgtc aatacttgtt acaaaacttt ctaattgaag atcttcaaga tttaacttga
    15841 ttttttctga ttgatttttc ataagattat aatttgtttt aatgttcatg aaacatcctg
    15901 gacgagccac aatggttcat caaaattcat gaagtataat gccactgtga taacgggttt
    15961 ttggcttatc cccggttgca acaatgctaa tatagttatt tgcaacatag ttgcaaagta
    16021 tatttgaagg aaaattaaaa taaatattca gttcattgaa ggctcgtaat aaccgggatg
    16081 aaggcaatga taaatggatg attccagcct ctttttactc taaaatataa tagcgggttt
    16141 gcagaggttc tggctaggta ccgtaggggt tgtggtacac attgaactag tattgaagta
    16201 gggttgaagt aggattgaag tagcctgggc tacttcaagg gtagtcgaat actagttcaa
    16261 tgctagttca acctacaaca caacccctac agtacctagc caaaacccct ataaaaaaag
    16321 agcagtaatc cggtgtaatc ccagaatgat ttagtgaagt taaatgacag gttcctgcat
    16381 agctgcagta cgcacttttt taagctccca tggagaaatt ttcttcttca ggaccatttt
    16441 ttcctgaacc aatggtttct tccctttttt ctttttgaat ttcttaccgt accatactaa
    16501 aaatccggta attggcagac ttgcagagat caggctggct aaaaaggcta tgattttggt
    16561 gggaaggccc atcaccgagc ccacgtgcag gtcatagttc attctcctga ttttatcggg
    16621 aatactcgca tcctcgtatt tccccagcag cggagagtta ccagcaaatt gcttcatcgt
    16681 atactgatcg aaagcgtatc tgtctgcttt ataaaatgta cctgctttta aataaacaat
    16741 aaagcctatg gcatcagaag attttgcagg aagcgtaata aacatacctg ctgcctgact
    16801 tgtcgtagcc agtttactgt aaattttatc aatatttttg ggctgaaaca cagcatttgt
    16861 agttgtatct gataaaggcc ttggctttgc ttctaaagat tttccacccg aagttaccca
    16921 gtataaagat ttgctatacc atttataact gtagacaaga cctgttaatg aaatcagcag
    16981 taagaccaga aagacataaa accctgcaac tttatgcaga tcatagttca cgcgtttaaa
    17041 gctgccactc catttaattt taaagctttg atccttgatt gatttgatcc actttttagg
    17101 ccaccacaaa acgataccgg aaattagtag gcacacaaag atcaatacac caactccgat
    17161 taccttggaa cctgtttttc ccatccagag tgtacggtgg ccgttcagaa taaaccggaa
    17221 gaaatcgaca ttgctccttt tgctcttgcg gtcaatgtga atgatctcgg cggtgtaagg
    17281 attcatataa ataaccaggc ttgtcccttt tttacggttt agagaattaa cggtagctgc
    17341 ttcatttttc tgtccgtaat tgatagaagt aggttttaat ttgcctaatt ctggctttgc
    17401 atgcgcgatt agctgggtcg gtaacaggaa agatttttcc tgaggttgta caaactgcca
    17461 tggctgatag aggcttctta tttctttttc aaaaacataa atacatcctg taatacttac
    17521 aataaataca atcaggcctg aagcaagtcc cagccataaa tgtaaccatg cattgatctt
    17581 ttttaaagtc ataaccggag cctaattgta aatcggggga aggtcaaagg ccttcatacc
    17641 atttatttag aatgaattaa gataaagaac gcaaagtaaa tgatattaat ttaagattcc
    17701 tagagatgtg tgtaatgatt ctaaataaat aggcgtaata caaatttgct aattctactc
    17761 agttatttat tttaaactat ttcacgtctt atttaacaat gactataaga actgaatttt
    17821 gttgatgagg atcatatttt gtgatgatca cagacatgcg ccagcacacc attttccctg
    17881 acctttatat aggcttaaca gatcaccaca ggttttttta gctgataatt aaaatgatat
    17941 gaataaattc ttaatcctag tggtactctc cttaactggc gttttccaaa tccgggcgca
    18001 ggagcctgtg aaacaagatt ccacagctaa aggaaagatt accatgcggg ggctatttca
    18061 ggcccggtat cttttcagcg gcaataaaaa tattgattta aatggtctgc atcatcttga
    18121 tggtaaagcg gtttataatg attttgatat taaacgtgca aggttgcaat ttacctcgaa
    18181 aatatcagat cgtacggatg tggtgttatt gctgaacctg gcagatttta aaactgaccc
    18241 caagaataaa gtattggaga atgcttatat cacctatagg ctggataatt ttataaatct
    18301 gaagatgggg caattcagac ctgctttcgg tctggaggat atgtatcctg ttgatgtgat
    18361 taaatccatg gattattcta atcagtacac cgctttcggg aataatggct ggcaaagttt
    18421 ccagattggg gccagtattt atggggcaac gcatggagag atccctgtca aatatgaact
    18481 ttctgtaatc aacggaaata acaggaatca actgatggat aatgacaatg gaaaacactt
    18541 ttctacccgg gtagaattag gcttgcaaaa aagtctgaag attaaattag gattgaatgg
    18601 tggcctggca accgtcttag gaagcaacgt atatgctgct ggtgtagatt tatctggtgt
    18661 tgttcccctg ggcaaaaagt ggtcgttgga aatagaaaca gaatttaagc agggaaataa
    18721 ccataccttt tattatggac tggattctgc taaacgtgtt ggcggagtgg acaattacca
    18781 gatgcatggt ctgtattttc tacccaatct caggtatgcg atcaattatc accgtttaag
    18841 ttctctggaa ttttcttgcc ggtacgagaa ttttaacaac gattttaaac atgctgctaa
    18901 taatccaaga caaacctgga ctcctatggt cagtgcagag tttttaaagg cttatagtgc
    18961 ccgtatccag tttggggtta atatcgaccg gtataaaaga aatattcccg gaactataca
    19021 atataataat gaaatgttta ttgtacaggt ccaatcaaga ctataagtta aaatacgatc
    19081 atgaaatcta cagctactac agcggcggcg gcgcctccaa aaaaagaaat tcaacctatt
    19141 ccattgctga ttaccgtggt attcggactc gcgatctggt ttattccggc gccagaaggt
    19201 gttaaacctg aagcctggca tttactggcg atctttctgg ctactattgt cgggatcatc
    19261 ctgaaagctg ccagtatggg cacgctttgt atgatggcta tcgcgctggt tgccatgacc
    19321 ggtgtgcttg ctccgggcaa tccgggaaaa tcaattacac tcgccttaag aagttttggg
    19381 gataaggtaa tctggctgat cgggatcagt ttttttatcg cccgtggctt tatcaaaact
    19441 ggtttaggaa gcaggatcgc ttatattttt atcaaattat ttggtaaaag ttctttgggg
    19501 ctggcttata gtctgggcgc tgccgattta atacttgctc cggctattcc aagtaataca
    19561 gccagaggcg gagggattat ttatccgatt atgaaatcta tggccatgag cctgggttct
    19621 atgcccgata aagcggaaac gcaccgtaaa gtaggggcat acctgacttt gaacagttat
    19681 tatatgaacc tgattgcttc ggctatgttc ctgactggaa ctgcgagtaa cccgatgtgt
    19741 cagaaatttg cagcagatat gggtatccat atcagctgga tgtcgtggtt ctgggcggca
    19801 attgttcccg gactggcctc cgtaattatt ataccttttt tattgtacaa gatttttcct
    19861 cctgagttga aaaaaacaac agaagcacca gcaatggcta tagcaaagtt gaaagagatg
    19921 ggggaaatta caaaaaatga atggctgatg ctgttggcat tcgtaatctt actggtactt
    19981 tgggtaactg gagatctgtt taaaattgat gcgacaacaa ctgcatttat cgggctttct
    20041 attttattac ttactcaggt attgacctgg gaagatgtca aagctgaaaa aggagcctgg
    20101 gatactattg tctggtttgc aacgctggtg atgatggccg gatcactcaa cgaacttggt
    20161 ttcattccct ggtttggaca tttaatacaa actttacttt taggaatgtc ctggacattg
    20221 gctttcccaa ttattatcgt tgtttatttt ctgagccatt acctgtttgc cagcgcaact
    20281 gcgcatgtag ccgcaatgta tgccgcttta ttagccgtag gcatcgctat gggcgtccct
    20341 ccattgttac tggcactgat gctaggtttt acaggttcct tgtttgggac cattacacat
    20401 tatgcacatg gccctgcacc agtatatttt ggaagtgggt atgtggatgt taaacagtgg
    20461 tggattatgg gattgatcgt cgggatagca ttattggcaa tctggatggg attaggtggt
    20521 ttatggtgga aagtcaccgg agtttattaa ataaaaagac atgaagttaa cctttcttaa
    20581 aagcacttta tcacggaaaa acctgatggc cctgaccgga ctgttcctgt gttttttcct
    20641 ggtgatccat ttactgggaa atttacagtt gctgctgcca gcagaccggg cagcagagcg
    20701 ttttaatcac tattctgatc ttttatcagg caatatattt attaaaatga tttcttatgt
    20761 actgtatctt tcactgattg cgcatgcagt ggatgcatta atcatcaccg tgagaaataa
    20821 acaaacggca acaaaatatg cttatgataa ccggaaacag gccagtaaat ggtattcaag
    20881 aaatatgggg atactaggta caatactctt gattttcctg gtcatccatt tcaaagattt
    20941 ctggtatgtc tataaattcg ggacggtacc ctttgatcga aatggaaata aggatttata
    21001 tgtagtagtt gtccatgcct ttaaatcatg gtggtatgta ttgctttatg tactgtcgat
    21061 gtttgcctta ggctttcacc ttttacatgg ttttaaaagt gctgtcagaa cattgggctt
    21121 ataccatccg ggatatgccg cgctcgtaca aacctttggt acagtgtaca gttatgcaat
    21181 tactatcggt tttgcagtga taccggttta tgttcacctt actcaattcg gattatggaa
    21241 ttagatgcta aaataccagc tggcccgtta gagactaaat ggagtcagta caaagcgcag
    21301 gctaaactgg tcaatcctgc aaaccggaaa aaattacctg ttattgtggt tggaaccggg
    21361 cttgctggcg catctgctgc tgcttcttta gctgaacagg gttatccggt cacttctttc
    21421 tgtttccagg attctgccag aagagcacat tcagtagctg ctcagggcgg cgtgaatgca
    21481 gccaagaact atcagaatga tggagactct gtttacagga tgttttatga tacgctgaaa
    21541 ggcggggatt tccgggcacg tgaagctaat gtataccgtt tagcggaatg ttctttaaat
    21601 ctgatcgatc aggcagtagc acaaggtgta ccttttgcga gggaatatgg cggatacctg
    21661 agtaaccgtt cttttggcgg agtgcaggtg agccgtactt tttatgcgcg gggacaaacc
    21721 ggacagcaat tgctgctggg tgcttatcag gcattgatgc ggcaggtttc tcttgggaaa
    21781 gttaatttat acagcaggca tgaaatgctg gatctggtgg tcatagaagg gaaagctaaa
    21841 ggaattattg caagaaatct ggacactgga ttaatagaac gttttgctgc cgaagctgta
    21901 gtgatagcta caggcgggtt tggtaagatt tattatttat ccacgctggc tatgggctgt
    21961 aatggctcgg ccatttggcg ggcacataaa agaggagcgc tgatggcttg tccaagctgg
    22021 acacaaattc acccgacgag tttacctcaa tcgggagatt atcagtcgaa attaacgctg
    22081 atgtcagaat cattgcggaa tgacggaaga atctgggttc ctcaattacc agatgaacaa
    22141 agggctgcaa atgatattcc tgaacaggaa agagattatt atctggaaag acgttatcct
    22201 tcgtttggta atctggcacc aagagacatt tcttccagag cagctaaaga aagaattgat
    22261 gctggtttcg gggtcggcgc acagcggaat gcagtgtatc tcgatttttc aaaagcaatc
    22321 aaagagcagg gcaaggagaa gatcaaagag aagtatggaa acctgttttc tatgtataaa
    22381 aagataactg ccgatgatgc gtatgctgca ccaatgaaga tttctcctgc tgcacatttt
    22441 tcaatgggtg gtttatgggt ggactatgaa ctgatgacta ctattccagg tttatttgcc
    22501 attggagagg ctaattttgc agaccatggt gcaaacaggc taggggcaaa ttctttgttg
    22561 caagcctgtg tagatggtta tttcatcctt ccatataccc tggctaatta tttatcaggg
    22621 gagttgaaga aagaaaagat aacgactgat catcctgaat ttgaccggac tgaaaaagaa
    22681 gttgtcacgc agctgaccgg actttgtgag ctcaaaggca caaaaacagc agattacttc
    22741 cataaaaaat tagggaaatt attatatgat aaatgtggtt tgtcacgctc tgctgaaggg
    22801 ttgacagcag ctattgaagg gattaaaata ttaagaacag cgttttataa agacctgatt
    22861 gttcctggaa cagctggtga aattaacagc gaactggaaa aagcaggcag ggtggctgat
    22921 tacctggaga tcgcagagct gatgtgtcat gatgcattaa gcagagaaga atcatgcggt
    22981 gcacatttca gggaagaata tcaaactgcg gatggcgaag cgttaaggga cgatgaaaat
    23041 tattgttacg tgtctgcatg ggaatggagg ggaaaaaata gtcttcctgt attacaccct
    23101 gagcacttaa aattcgaatt tattaaatta tcagtaagaa gttatagtta ggaatcatga
    23161 agatacatct taaaatatgg cgtcagaaag atgcaaaagc taaagggaaa ctggtagatt
    23221 atatgctgga tcaggtggat caccacatgt cttttctgga aatgatggat actttaaatg
    23281 agcagctgat ccttaaggga gaaatgccag tggagttcga tcatgattgc agggagggaa
    23341 tttgcggaac ttgcgggatg atgatcaatg ggcaggctca tgggccggtt ccgggtttaa
    23401 cagcatgcca gctgcatatg cgggaatttg aagatggtgc tacaatttat gtggaacctt
    23461 tcagggctac tgcttttcct gtaaagcgcg atcttaaggt tgaccgttca gcttttgacc
    23521 gtattataca ggcgggtgga tttattacgg ctaatactgg acagcctgtg gaggccaata
    23581 ctttattgat tacgcacgaa actgcggaat ctgcttttga ttcggctgct tgtattggct
    23641 gtggtgcttg tgtggctact tgtaaaaatt caagtgctgc cctttttact tctgccaagg
    23701 tttctcatct ggccaaaatt ccgcagggag aaaaagaagc ggcgaaaagg gtactgaaaa
    23761 tggtttcccg tatggatgaa gagggttttg ggcattgcag taatacggaa gcttgtgagg
    23821 tggagtgtcc gcagggaatc tctgtgctga atatcgcaag gatgaactgg gagtatacga
    23881 aagcgaattt gctgaaagat taaaataaat tttcaattgc tgtagcgttt gctgatttgc
    23941 ttacgtttta cagtcaatag gttagattcg aactccggaa tcgggtaatg gtagttgcct
    24001 aagggatctt catcggtgtg ttttgttgct tgccaatgta gataataaaa ggaatttgaa
    24061 cttttgggta gatgaaattc cgtacacaca cacacacaca aatggataca atagcccctc
    24121 tttttatgga ggggctttgt tttttttggg atattttatc aatgggatat tttaccagaa
    24181 aaggctgtat aaggcaacga taattccccc tacgatcaat gatcctatag cgaaactctg
    24241 attggtttta aacatagatc tgtcaacctc aagtccttta gggttgatgc cgttcctgtt
    24301 ttccagttta ctgatgatga acatggcaat tacacaaatt gcaaatacaa agcccatccg
    24361 gtcaatgaat gggatctcat acaacatcgc accatttttc tgttccacca attttgaaaa
    24421 accataaggg cttaaccatt ccaggttagc aaataatggc agggctttaa acacaacgga
    24481 caggataaaa ccaccgatag ttgcaaataa tgctgcattg gaagttgttc ttttccagaa
    24541 gaaccccaat aagaacatgg caaaaatacc cggagaaaca aaaccagtat attcctggat
    24601 aaactggaaa cctccttttt tatcaattcc gagttgtggt gcaataatga tcgcaaggac
    24661 catggctaca ataactgtaa tccggccaac gataacttgt ttattctcgt ccgcatcttt
    24721 attgattact tttttgtaaa catcaagtgt aaatatggtc gcgatgctgt ttgcttttcc
    24781 tgcaagagaa gctacgatag cggctgttaa agctgcaaaa gataaccctt ttagtccttg
    24841 cggtaaaagg ttaagcaata caggataagc tgaatctgca tttaacgagc catctttcaa
    24901 catggctttt tggaaatccc catagccttc tttgtacaat acataagcag caatacctgg
    24961 taaaacaacg atgactggca tcagtaattt caggaatgca gcaaataata atccactgcg
    25021 ggccgttttt aaatcagcac ctaatgctct ttgtgtaata tattggttac agccccagta
    25081 gttgaggtta acgatccaca ttccacctat caatactgat aaacctggca aatccatata
    25141 gtttgcatct tctttgtgga aaatcatctg gaagtgatca acagcttttt ctttgatgag
    25201 tgacaacccg ttaaatacac cggtggtccc aaaatgtgta gagactaatt ccagcgcaag
    25261 gtaggttgtg gccagaccac caaggatcag gaaaaatacc tggataacat ctgtataacc
    25321 gattactttc atcccgccga gggtaataat tacggcaaaa acagagagta cgtacataca
    25381 ggcggtaata ttaatccctg agatactgtt aatagctaaa gcgccgaggt aaaggataga
    25441 ggtcaggttg acgaccacat acagtaagag ccagaaaata gccatgatca ttgctacagt
    25501 actgttgtac cgctgtccca gaaattgggg catcgtatag attttattct tgatatagac
    25561 aggaataaaa aatatagcga caataatcaa ggtggcagcg gctaaccatt cgta
//
