LOCUS       NZ_CP014504            23014 bp    DNA     circular CON 03-MAR-2024
DEFINITION  Pedobacter cryoconitis strain PAMC 27485 chromosome, complete
            genome.
ACCESSION   NZ_CP014504
VERSION     NZ_CP014504.1
KEYWORDS    GSC:MIGS:2.1; RefSeq.
SOURCE      Pedobacter cryoconitis
  ORGANISM  Pedobacter cryoconitis
            Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
            Sphingobacteriaceae; Pedobacter.
REFERENCE   1  (bases 1 to 5950539)
  AUTHORS   Lee,J. and Kim,O.-S.
  TITLE     Complete genome sequence of Pedobacter cryoconitis PAMC 27485
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5950539)
  AUTHORS   Lee,J. and Kim,O.-S.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAR-2016) Division of Life Sciences, Korea Polar
            Research Institute, 26, Songdomirae-ro, Yeonsu-gu, Incheon 21990,
            South Korea
COMMENT     ##MIGS-Data-START##
            alt_elev                          :: 1 m
            assembly                          :: SMRT Analysis v2.3.0
            collection_date                   :: 2014.01.03
            country                           :: Antarctica
            depth                             :: 5-10 cm
            environment                       :: soil
            investigation_type                :: bacteria_archaea
            isol_growth_condt :: 0.1x Tryptic soy agar, celsius degree 20
            lat_lon                           :: 62.236389 S 58.71772199999998 W
            project_name :: Genome sequencing of Pedobacter cryoconitis PAMC
            27485
            sequencing_meth                   :: PacBio RS II sequencing
            geo_loc_name                      :: King George Island
            env_biome                         :: ENVO:01000186
            env_feature                       :: ENVO:00000097
            env_material                      :: ENVO:00001998
            ploidy                            :: haploid
            num_replicons                     :: 1
            ref_biomaterial                   :: not applicable
            source_mat_id                     :: PAMC 27485
            biotic_relationship               :: free living
            trophic_level                     :: chemoheterotroph
            rel_to_oxygen                     :: aerobic
            assembly_name                     :: ASM118778v1
            finishing_strategy :: complete; 110x coverage; 1 contig
            annot_source                      :: prodigal v2.6.1
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 110x
            Sequencing Technology :: PacBio RS II with P6-C4 chemistry
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 09:48:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,049
            CDSs (total)                      :: 4,958
            Genes (coding)                    :: 4,943
            CDSs (with protein)               :: 4,943
            Genes (RNA)                       :: 91
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 15
            CDSs (without protein)            :: 15
            Pseudo Genes (ambiguous residues) :: 0 of 15
            Pseudo Genes (frameshifted)       :: 3 of 15
            Pseudo Genes (incomplete)         :: 14 of 15
            Pseudo Genes (internal stop)      :: 2 of 15
            Pseudo Genes (multiple problems)  :: 3 of 15
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:50:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1886939
            Orig. end                         :: 1909953
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP014504.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23014
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="9"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23014
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23014
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13014](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13014
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            889..1974
                     /locus_tag="AY601_RS08035"
                     /old_locus_tag="AY601_1628"
     CDS             889..1974
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013740.4"
                     /locus_tag="AY601_RS08035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1628"
                     /product="AI-2E family transporter"
                     /protein_id="WP_068398953.1"
                     /transl_table=11
                     /translation="MTNQYPKDLYKIITSVILYTFGLVVLLWFLYQIMSIFILFIFAIV
                     LGLIINQPVSKLEKKGMKRWLASLIVLGIIFIVSTLLGFLVVPHISEQIDTLVGDLPGY
                     FNSISAHVTHMLRKYPELNKELQGDGLSISEAVPSLGKTVIGLSSISFSVLGGIFMFIV
                     FLSMIIFFVGNPRPIINMYLSVFEPEKRGKAERALQHTSIMLGGWMKSNLIGGIVQAIL
                     VYIFLTIMNVPGALVWAALAFFSELIPKIGFYIMAIPPTLVALSISPATAFWCLVFFLL
                     LNELISDFVMPKLRSSTMNIHPVSLLFLLLAMTTAFGLMGALLAAPMAAIIKAYYEEFY
                     LRRFPDDPDMDQRIDNILYKQ"
     gene            complement(2095..2490)
                     /gene="tssD"
                     /locus_tag="AY601_RS08040"
                     /old_locus_tag="AY601_1629"
     CDS             complement(2095..2490)
                     /GO_component="GO:0033104 - type VI protein secretion
                     system complex [Evidence IEA]"
                     /GO_process="GO:1901998 - toxin transport [Evidence IEA]"
                     /codon_start=1
                     /gene="tssD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008245098.1"
                     /locus_tag="AY601_RS08040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1629"
                     /product="type VI secretion system tube protein TssD"
                     /protein_id="WP_041878824.1"
                     /transl_table=11
                     /translation="MAFKTRLTLGSKEFDVLQCSYSLNRDVDAKGRPSSGVYGGTIHLE
                     IESTEDTSVIESMVNNQYKPQAGTIVFKKGEEDAKMKELHFEDGYIIQYNEGIAVNDNT
                     PMTLSFVVSARKLKIGNAEHTNDWPKA"
     gene            complement(2530..2925)
                     /gene="tssD"
                     /locus_tag="AY601_RS08045"
                     /old_locus_tag="AY601_1630"
     CDS             complement(2530..2925)
                     /GO_component="GO:0033104 - type VI protein secretion
                     system complex [Evidence IEA]"
                     /GO_process="GO:1901998 - toxin transport [Evidence IEA]"
                     /codon_start=1
                     /gene="tssD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008245096.1"
                     /locus_tag="AY601_RS08045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1630"
                     /product="type VI secretion system tube protein TssD"
                     /protein_id="WP_068398956.1"
                     /transl_table=11
                     /translation="MAFKARLNFSGKEYDVLHCAYSLNRDVDAKGRPSSGVYGGTIDIE
                     LESTEDTSVIEAMVNNQYKPLAGTLLIKKSEEDAKMKEVHFEDGYIVKYTEGINITGDN
                     PMTLKFQISARKLKAGNAEHVNDWPKA"
     misc_feature    3110..3123
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 25.52"
                     /tool="antismash"
     misc_feature    3132..3145
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 22.73"
                     /tool="antismash"
     gene            3408..4769
                     /locus_tag="AY601_RS08050"
                     /old_locus_tag="AY601_1631"
     CDS             3408..4769
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013667239.1"
                     /locus_tag="AY601_RS08050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1631"
                     /product="DUF1080 domain-containing protein"
                     /protein_id="WP_068398960.1"
                     /transl_table=11
                     /translation="MNKKHLLTLAGLLLVSLPATLHAQNQKWQNLFNGKDLTGWKQLNG
                     QAKYEVTNGEIVGTTVSNTPNSFLATAKNYSDFILELELKVDNSMNSGVQVRSESNAEY
                     QNGRVHGYQVEVDPSDRKFSGGIYDEARRGWLYPLDINPKGQQAFKNEQWNKYRIECIG
                     NSIRTWINGVPTANVIDALTPTGFIALQVHAIGKDDQPGKQIHWRNIRIQTEQLKPSKA
                     DDIYVVNLVPNTVSPQEKAEGYSLLWDGKTNTGWKGAYKATFPESGWVIKDGELSVQKS
                     NGAEATNGGDIVTEKQYGAFELKFDFKLTEGANSGVKYFVTLTEGNKGSAIGPEYQILD
                     DERHPDAKLGKNGNRTLGSLYDLITSKKIPNAQRKIGEWNSGLIRVYPNNKIEYWLNGY
                     KILEYVRGSADFLALVADSKYKDWKNFGMAPKGHILLQDHGDQVFFRSIKLKQL"
     gene            4782..6140
                     /locus_tag="AY601_RS08055"
                     /old_locus_tag="AY601_1632"
     CDS             4782..6140
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008238615.1"
                     /locus_tag="AY601_RS08055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1632"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_068398963.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 4.4e-14, bitscore:
                     51.4, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSSRRKFIKQTAIAAAGTYMGTMGLSAKSYGNIIGANDRVRVGV
                     VGFSDRFATSLFPSFLNHYKELNFDIVAVSDLWNYRRGLGENFLKAKLGHDITACRNND
                     ELYQLKDLDAVIVSTADFQHAVHAIEAINAKCDVYCEKPFAETMSDARATLKAVKASQQ
                     ILQIGSQRRSGANYIAAEQFIKSGKFGDITMVELSWNVNQPGRWRRPDLVAKLKQEDTD
                     WKRFLINRPFEEWDPRIYLEYRLFWPYSSGMPGQWMSHQIDTVHWFTGLKHPRSVVANG
                     GIYQWKDGRRNWDTTTAVFDYGQENNPENGFQVVFTSRMHNGDENPAEIYYSNGGELNL
                     NTNLVSSKGGLKADAANAMHMQPNLLPELKLTNVTEKVAASANTGGDKLTSAHMRNWME
                     CIRSRKEPHAPVEVGYYHSIANIMTNAAVRTGKKAVFDEATQEVMVDGKVFKY"
     gene            complement(6192..6428)
                     /locus_tag="AY601_RS08060"
                     /old_locus_tag="AY601_1633"
     CDS             complement(6192..6428)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AY601_RS08060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AY601_1633"
                     /product="hypothetical protein"
                     /protein_id="WP_068398965.1"
                     /transl_table=11
                     /translation="MADWYIKASRANPFNPDSYTLIGSTAPACPGNLGFVCAIFAEDNG
                     RRKPVIDEDLSDEIWSAINTETDQTRVLLRAIS"
     misc_feature    complement(6453..6462)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     misc_feature    complement(6630..6649)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 21.99"
                     /tool="antismash"
     gene            complement(6801..7451)
                     /locus_tag="AY601_RS08065"
                     /old_locus_tag="AY601_1634"
     CDS             complement(6801..7451)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025736.4"
                     /locus_tag="AY601_RS08065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1634"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_198163643.1"
                     /transl_table=11
                     /translation="MIWKAVKHCPLFFAVLVSILMIGLISCALTSKLTSFNFLNFYHRP
                     FLDVFFSYYTFIGDGLMCLLTIIVLLFLKRKKLSLALLLAFLGSGLIVQILKKLLHEPR
                     PSLYFDQIGFKYSYFVIGIQKMQSASFPSGHSASAFAMCIVIALYFKDKRVSILCLFLA
                     LFAGYSRIYLAHHFLPDVMAGALIGSVSGLLTYYFTWHPADIYTKVNIDFKGR"
     gene            7611..8510
                     /locus_tag="AY601_RS08070"
                     /old_locus_tag="AY601_1635"
     CDS             7611..8510
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010601454.1"
                     /locus_tag="AY601_RS08070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1635"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_068398971.1"
                     /transl_table=11
                     /translation="MNYSISDLEQLSGVQVHTIRIWERRYNALEPMRSAGNTRMYNEDH
                     LKRLLNIVSISQTGLKISQVCALSEKEMNDFLKKEIEQTISNDAHFEYYTSQLLKCGLI
                     YNESEFDHLINKCILENGMIITYQQVIYPLLVRLGLMWRKDDICPAQEHFLSNMIRQKL
                     YAAINELPAVTQVKSSWLLFLPEAEGHDIGLLFANYILKQAGQKVIYLGGRVPLDSVKN
                     AMQNKQIKHMLLFMVRIQPLELANSYLNELSTTYPETRIHLAGNGKLINELKMGKNINW
                     FQSINEFQQTIKSVSNAN"
     misc_feature    7634..7650
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 21.98"
                     /tool="antismash"
     gene            8500..10017
                     /gene="crtI"
                     /locus_tag="AY601_RS08075"
                     /old_locus_tag="AY601_1636"
     CDS             8500..10017
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008241583.1"
                     /locus_tag="AY601_RS08075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1636"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_068398974.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 7.1e-07, bitscore:
                     26.9, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 1.1e-11, bitscore: 43.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTKTAQQTPRIAVIGAGFAGISAAAYLAKNGYKVDVYEKNSSVG
                     GRARQLETENGYVFDMGPSWYWMPDVFEKFFNDFGHQAKDFYELELLDPGFSVVYGQND
                     VLDIPADFNALCETFEAIEPGSAIKLQQFLEEAAYKYKTGIEKLVYKPGLSLMEFADMD
                     LIKGVFKLQVFTSFSSHVKKYFKHPKLIALMEFPVLFLGATPEDTPALYSLMNYAGLKL
                     GTWYPKGGFGKVIEAMKTVAEKNGVKFHLNEPVSALEIEGKEIKALSSSKQTKAYDGYI
                     AAADYHHVEEKLLGENYRNYQEKYWDKRVLAPSCLIFYLGVTRKTERLGHHTLFFDEDL
                     KQHAIEIYKEPQWPSKPLFYVCCPSRTDTTVAPDGHENLFVLMPLATNMEDTEAQREKY
                     FELIMNRLETYTGVEIRKHLNYKNSYCVADFKLDYNSYKGNAYGLANTLMQTANLKPSL
                     KNKKVKNLFYAGQLTVPGPGVPPSIISGHVAASQLIKYFNKNYERDI"
     gene            10001..10837
                     /locus_tag="AY601_RS08080"
                     /old_locus_tag="AY601_1637"
     CDS             10001..10837
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008241585.1"
                     /locus_tag="AY601_RS08080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1637"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_068398976.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.7e-36, bitscore:
                     122.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.1e-37,
                     bitscore: 127.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEIFDRLSAECSKITTKRYSTSFSLGIYFLGKKLRNPIYSIYGF
                     VRLADEIVDSFHDFDKHFLLAKFRQDCYEAIEHKISLNPILNSFQQVVNEYAIDKELIE
                     LFLKSMAMDLDKKQYSPEMYNQYILGSAEVVGLMCLNVFTEGDKVQYERLKDSAMKLGS
                     AFQKVNFLRDINADYFNLSRTYFPNIDLTIFSNHEKQIIEKEIEEEFKQALAGIKQLPA
                     SSKNGVYLAYIYYKELFNKIKGTTAEKVMSKRIRISNSHKFGLMCDSIIRYKMNAI"
     gene            10834..11328
                     /locus_tag="AY601_RS08085"
                     /old_locus_tag="AY601_1638"
     CDS             10834..11328
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AY601_RS08085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AY601_1638"
                     /product="hypothetical protein"
                     /protein_id="WP_157287783.1"
                     /transl_table=11
                     /translation="MKTLTLFILFMYGSHSYPEITELRTLYYESANDKAAAGKLLDLLS
                     NVDDQSSQLLICYKGVAEMMQAKYTMSPISKFRRFKKGKEYIESAVAIDPENLEIRFLR
                     FTIQTNLPSFLGYNDHIIADKTILIKNLDQIHDKPFKQLVINYLFASKNMTEKERNSIK
                     K"
     gene            11325..11852
                     /gene="idi"
                     /locus_tag="AY601_RS08090"
                     /old_locus_tag="AY601_1639"
     CDS             11325..11852
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008241588.1"
                     /locus_tag="AY601_RS08090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1639"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_068398979.1"
                     /transl_table=11
                     /translation="MKDHVILVDQIDQETGLMEKMEAHQRGKLHRAFSVFIFNQKGEFL
                     LQQRALEKYHSGGQWSNTCCSHPYPGEDTATGAKRRLQEEMGMDCELEFGFSFIYYAEL
                     KDGLSENEFDHVYFGISNTIPVPNPDEVAAFKYVTLETLETQLKTNPEHYTIWLKICFD
                     RVKSHYNQLFNL"
     gene            11849..12322
                     /locus_tag="AY601_RS08095"
                     /old_locus_tag="AY601_1640"
     CDS             11849..12322
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008241589.1"
                     /locus_tag="AY601_RS08095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1640"
                     /product="sterol desaturase family protein"
                     /protein_id="WP_068398986.1"
                     /transl_table=11
                     /translation="MSNWIINTLIVAATFIGMEGVAWFTHKYVMHGLFWNLHRDHHHKD
                     HEGFLERNDFFFLIFAIPGIICLGLGSFYGNTIALYIGIGITLYGAAYFFIHDIFIHQR
                     FKIFRKSDHWYFKAIRRAHKMHHKHINKEHGECFGMLWVPFKYFFENNKKTEA"
     gene            12319..13014
                     /locus_tag="AY601_RS08100"
                     /old_locus_tag="AY601_1641"
     CDS             12319..13014
                     /GO_function="GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF039186.3"
                     /locus_tag="AY601_RS08100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1641"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_068398988.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 7.7e-20,
                     bitscore: 69.4, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYAYLLIDFFTISVPFIYSFHPKLNFYKTWKAFFPAVFLTGMMF
                     LIWDVYFTSLGVWGFNPDYLIGLKVGNMPIEEILFFFCIPYACVFTFHCLDLFIKKPIP
                     LRIEKILTPLLILICVLMSILYRNHIYPAATFLLLAAVLTLSRYILKIGWLPKFYIIYT
                     VLLFPFLIVNGLLTGTGLDAPIVWYDNNQIIGFRILSIPIEDVFYGMALILVNLLIYKH
                     LLSRRSAAQ"
     misc_feature    complement(13030..13039)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            13328..14074
                     /locus_tag="AY601_RS25905"
                     /old_locus_tag="AY601_1642"
     CDS             13328..14074
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012371.4"
                     /locus_tag="AY601_RS25905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1642"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_198163644.1"
                     /transl_table=11
                     /translation="MSTFKKSAINLFAITILLVSTQKTNAQTTKSAQLDSLVHQANHLG
                     LFNGNILIAENNKVIYKNAVGFADAAGKIKLTEQYRFHIGSIAKEFNAVGIMILKEQGN
                     LSLEDPVSKYLPELPAWASKIHIINLLQYTSGIPDVKWKSVKSNADNMEDLKKTTRLDF
                     EPGTQYAYNNNNVFLQRRIIEKITGLSFTAFTEKYILKPCRMKTAIVDPVATDKFIARA
                     YNNDHAEDELTYPINGWVAVTLVRFL"
     gene            14178..14732
                     /locus_tag="AY601_RS25910"
                     /old_locus_tag="AY601_1643"
     CDS             14178..14732
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019339.4"
                     /locus_tag="AY601_RS25910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1643"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_198163645.1"
                     /transl_table=11
                     /translation="MLEANRVITHKHDGTARNYQALLVSTVSKGRTVILMTNNQQNNLY
                     TFNVSIQAILDEKPYTQIKKSVLGTFGKQIDQLNGTEVITFYEKMKKEHNDEYSFDAEA
                     TLNEIGYNFLRQKKFTDAILIFEHNTKLFPESGNVFDSLGEAYYKQGDKSKALLNYKKS
                     IVLNPENGDAKKIIAELSSKF"
     gene            14933..17362
                     /locus_tag="AY601_RS08110"
                     /old_locus_tag="AY601_1644"
     CDS             14933..17362
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1082:
                     TonB-dependent siderophore receptor family"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012801.4"
                     /locus_tag="AY601_RS08110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1644"
                     /product="TonB-dependent receptor"
                     /protein_id="WP_198163646.1"
                     /transl_table=11
                     /translation="MKPLLLTTLLFLFYFIPNTLHAQQTVKINGTVIDGKQTLPAATVL
                     LYTAKDSALVTTAMTDQDGKFNFTAAPSKYYIVSSSIGYNKVKTAPFQLTGPAALQIPA
                     ITLKENSKNLNEVSITAAKPVLERKADKLIFNVDATPSAAGLTALEVLKKAPGVNVDYN
                     ENISLSGKSNVLVTIDGKQTYLSSTEVVNLLKSMQSNQIESIEIINNPGSRYDANSTGG
                     IINIKTKKSNTEGFNGSVALGAGFNKYLLPNGSINLNYRKKDFNVFGSYGYNRNKSLQT
                     LKIDRITPGTNPLSFSQRNKDTSVYSSQNFKIGTDFFLSPKHTIGFLVKGNISDYNQQS
                     LSMVNIGKSFAATDSVLKTPSYNSSNRKNFSYNINYKGVLDTAGQEITVDADYSTFDGT
                     NNANYTNRFYLPNGTFFKDGQIYRNFAPSNIDIKAIKADYTLPINKMFKLEAGTKIASV
                     KSDNNYIYENDIKGNWVFDNTKSNRFLYDEKVSAAYATLYVTLGKTSLSGGLRAENTNS
                     TGNSITTNQLTNRKYTDLFPSLSLSQNIDADNTLNFSYSRKINRPNYQNLNPFVFFLDQ
                     YTYNQGNPNLKPEYSNNLEASYLFKQKYSLALNYSRTTDVITQVLLQNEVRKSMYQTIL
                     NLASESVVSLTFNFPVTVTKWWNMNNNVLGYFKQIKAPDLNGADLNSKQFSGNFYAQNN
                     FTLSKLFSADAGLMFSTPQIEGAFKVKSMYNADAGLRYNFPNKTGNLKLGVNDIFHSQK
                     ARIFSTLPGNVYNLEQYGNTTSVRLTFTYRFGKMTVKSARNRSTGLDDEQKRLGGK"
     gene            complement(17440..18147)
                     /locus_tag="AY601_RS08115"
                     /old_locus_tag="AY601_1645"
     CDS             complement(17440..18147)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AY601_RS08115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AY601_1645"
                     /product="hypothetical protein"
                     /protein_id="WP_068398999.1"
                     /transl_table=11
                     /translation="MFIIYDIKEKTLNSRTVLIETDSLTRSKSDVQLDVYQQYMSIFGP
                     LGPLGGQQVRAIDLNQNVEIPKKEWSEELKAEAQNLKAETPFAWGLFQNIFIIAGVFIG
                     LAVIGPILNKNRAEKAAVASEARAASLVAVAPGDVLRVFLMPSPEMTEPQVTLMKVVRI
                     EGDTLVVKGHKEVKKGFSAEDAAALDHHDAAFNAEEKKYNFRNFKSNKLISEFPASSHK
                     NIGTVLDAVKSTT"
     gene            complement(18248..18682)
                     /locus_tag="AY601_RS08120"
                     /old_locus_tag="AY601_1646"
     CDS             complement(18248..18682)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AY601_RS08120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AY601_1646"
                     /product="hypothetical protein"
                     /protein_id="WP_068399001.1"
                     /transl_table=11
                     /translation="MNYFIFTKYTTGQHSRKITFIFALLVLLFSCKKETGRQPVYAQKE
                     VTIEYKISPYQNVITGGHIIYTDEAGVVTVADKKTLPFSRKFKTTIKRSAVLSLGIIAE
                     YAGSVKMEILVDGQVVSALISSSIFNKREMIRYTITVPQE"
     gene            complement(18771..19436)
                     /locus_tag="AY601_RS08125"
                     /old_locus_tag="AY601_1647"
     CDS             complement(18771..19436)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014025.4"
                     /locus_tag="AY601_RS08125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1647"
                     /product="MarC family protein"
                     /protein_id="WP_068399003.1"
                     /transl_table=11
                     /translation="MPLLYHSFFHLLFIGIIALFPVVNPIGSSFIISPFFTGLSSAEKR
                     KAVGKITFYAFSICTVSLFAGQWILELFGISIPVVQLAGGIMICKMGWENLSSDKKQTT
                     STMDAETNLSGYSHIENQLFYPITFPVTTGAGTISVLFTLSAHSISSNRSDDLMNTAAI
                     LSAIIVMCILIYIFYLNTKNIIHYLGSNAEAIFNRISAFLIFCVGLQIAITGIKSLMK"
     gene            19732..20472
                     /locus_tag="AY601_RS08130"
                     /old_locus_tag="AY601_1648"
     CDS             19732..20472
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016195171.1"
                     /locus_tag="AY601_RS08130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1648"
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="WP_068399006.1"
                     /transl_table=11
                     /translation="MKSFIETIKSIELETPVDKIIGQLKQLITSGQLQPGDRLPAERIL
                     AEKFGVGRSYVREAILKLEFYGLLKTNPQSGTYVAGLSIKVLDSIITDIIKFNKEDFNA
                     LLEARYYLELDAVKLAAERRTEKDLESLKEALMDYEAKVNANQNAVEEDMIFHIRIAKA
                     SKNSVIESMILILIPDLIKSIVENKICGDNRGKLAIEEHRKILKAIVDQDIDAAENAVA
                     AHLNDMFQLSKAGFAAQKIIQDKV"
     gene            20525..22663
                     /locus_tag="AY601_RS08135"
                     /old_locus_tag="AY601_1649"
     CDS             20525..22663
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016195170.1"
                     /locus_tag="AY601_RS08135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1649"
                     /product="heparinase II/III family protein"
                     /protein_id="WP_232324720.1"
                     /transl_table=11
                     /translation="MMNYLKKLVMGLICLIFGLSAYAQQHPSIMLTKDNIGALRKGIST
                     YPLLGKSYKKIKSEADKAIKEPVNVPVPKDAGGGATHEQHKKNYLNILNCGIAYQMSGD
                     KKYAAYVEALLLKYASEYQKWPLHPKRKEGHQGGRIFWQSLNDFVWQVYTIQGYDLVYE
                     AIAPAQRQQIEKGLFVPAVKFFTEDCAETFNKIHNHATWAVAAVGMTGYVINKPEYVEM
                     ALKGTAKDGKAGYLAQIDQLFSPDGYYTEGPYYQRYALLPFLIFAKTINNYQPALKIFQ
                     YRKQLLAKAIETSLQLTYTDGTFFPFNDAVKGKTYESAELVYGVDIAYADIKSQPELLD
                     IVQKQGQVIISDAGLKIAADVAAGKTKPFVYKTLLITDGATGKDGGIGILRAGTNEDQQ
                     AVLIKATSQGMGHGHFDRLNLLYDDNNVEVFPDYGSARFINIESKKGGDYLPENKSWAK
                     QTIAHNTLTVDETSNFKGNADRAQQTAAEILYFKDDQDLKVISAAENNAYPGVKMTRTT
                     ALLKVEELQKSLMIDVFRVDADKAHQYDLPFWYKGHLTDSSLQLKSFADQLKTLGTQYG
                     YQHIWLNAEQAVPEQTGYLTLLNNKRFYTVNFAAQSPVNLKLLTLGAHDPDQNLLESKA
                     FMLSSTGSKTQTFFTVTETHGSTNTVDETTSGSSSSVSDLKIITAGPEQISVSFKVKGK
                     LYHYQINFKNKENFIKVN"
     gene            22669..23004
                     /locus_tag="AY601_RS08140"
                     /old_locus_tag="AY601_1650"
     CDS             22669..23004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003003146.1"
                     /locus_tag="AY601_RS08140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1650"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_068399014.1"
                     /transl_table=11
                     /translation="MLQSNLFQIEEETPWQDLGNGVKRQVFGYNDQIMLVKAKFEAEAI
                     GQLHQHHHAQVTYVDSGVFEMSIGEEKKILKKGDGFYAPPHEMHGCVCLEEGVLIDVFS
                     PHREDFL"
ORIGIN
        1 tcttaagcca gatttgcgtt ttctagtggt tttaacgcta atcagcttat atctgatttg
       61 ctggttttgt atctcattct ggataatctc gtatggtaag tcttctagtt ttaacgcagt
      121 ctgccttatt gcaatctggg tggccatgaa tataatttct cctgccattt tgaatgtatg
      181 gctaactaaa aaatatcctg tcccggaagc attggaaaat gtagtgaaac agcgggaagg
      241 ctatcatgaa aaatgggatc tggataaaag tgcaacaatg gataagttct accagcacta
      301 tcctcagttc agacaatatc cttttccctc ctcacttact tttagctggt attggtatta
      361 tgcgatgcag caaatgggag atgatgatgc tgctttgagt tccgccagga ttactgagaa
      421 attaaaacaa agacagcatt tcaccaatat cgcttctttg tttttacctg gaatacaaac
      481 gcaagcgggt ttaaatgaac ttgctggttc tgatctgcaa aaccatactg actttttact
      541 aacattaaga gcttaccacg aaaaaatgcg gttgtttttt tatccatcag tttttaaggg
      601 tagtaaagtt gaaaatataa attggaaaca atttaaaatt aaacaataca gtagccatac
      661 ggatggatta gcctggcaaa agctactttc gttaattgtg ttttcaattg tgcctgcgtt
      721 atcgggagtt tataacttca gtaagagaga tagtttatta taaattaaaa tgaggcagct
      781 aaaattaaac tgcctcattt caatgtggat tcacattagt caaaacatta tttttcgtac
      841 tgtgttaaaa ttatagtatt tcttatataa agcaataatc attagcacat gaccaatcaa
      901 tacccaaaag atctttataa aatcatcacc tctgttatct tatatacatt tggtttagtt
      961 gtgctattat ggtttctcta ccagatcatg agcatattca tcctgtttat atttgcaatt
     1021 gttcttggac tgatcattaa tcagcctgtg agcaaactgg aaaagaaagg catgaaacgg
     1081 tggttagcct cactcattgt attaggaatt atttttattg tctctactct gctgggattt
     1141 ctggttgtcc cacatatcag cgagcagata gatacattgg taggagatct gcctggctat
     1201 tttaatagca tatcagctca tgttacgcat atgctgagaa aatatcccga gctgaataag
     1261 gaacttcagg gagatggcct gtcaatttct gaagctgtac cttccctggg aaaaacagtt
     1321 atcgggctca gcagtatttc ttttagtgtg cttggtggga tatttatgtt tattgtgttt
     1381 ttatcaatga ttatcttttt tgtaggaaat ccgaggccga tcattaatat gtacttatca
     1441 gtttttgaac ctgaaaaacg cggaaaagca gaaagagcat tacagcatac ctcaataatg
     1501 ttgggtggat ggatgaaatc aaatcttata ggtggcattg ttcaagccat attagtctat
     1561 atattcctta cgattatgaa cgttccggga gctttagtct gggctgcttt agcctttttc
     1621 tcagaattga ttccaaaaat cggcttttac attatggcca ttcctcctac ccttgttgca
     1681 ttatctataa gccctgctac tgcattttgg tgccttgtgt ttttcttatt attaaatgag
     1741 ttgatttctg actttgtcat gcctaaacta aggtcatcaa ccatgaatat tcacccagta
     1801 tcactgctct ttctattgtt ggcgatgact acagcttttg gtttaatggg agcacttctt
     1861 gcggcaccta tggctgcgat tatcaaagca tattatgaag agttttattt gcggagattt
     1921 cctgatgatc cggatatgga ccagagaatt gataatatcc tttataagca gtaaaataga
     1981 acgcatataa ggtaattaac aatttaatat agagaagaat taagttggaa actattgaaa
     2041 aaactgcagg aaaccgtccc ggctccctgc agttaaagca ttggattggg ctaactaagc
     2101 cttaggccaa tcattggtat gctcagcatt accaatctta agtttacgcg cagatactac
     2161 aaagctcaaa gtcattggag tattgtcgtt tacagcaatc ccttcattgt actggatgat
     2221 gtaaccatct tcaaaatgca attctttcat ttttgcatct tcttcaccct ttttaaatac
     2281 aattgttcct gcttgtggtt tatactggtt attcaccata gattcaatca ctgaagtatc
     2341 ttcagttgat tcaatttcta aatgaatagt accaccataa actcctgatg acggacgtcc
     2401 ctttgcgtct acatctctgt ttaatgaata gctgcattgc agcacatcga attctttaga
     2461 ccctagagtc aatctggttt taaatgccat gataattttt ttttaaatgt taaacttcct
     2521 gaatttgaat tacgcttttg gccaatcatt aacatgttcg gcattccctg cttttagttt
     2581 gcgcgcagag atctggaatt tcaaggtcat tggattatct ccagtgatgt tgattccttc
     2641 ggtatatttc acaatatacc cgtcttcaaa atgaacttcc ttcatcttgg catcttcttc
     2701 tgattttttg atcagcagcg tgccggctaa aggtttgtac tggttgttta ccattgcttc
     2761 gatgacagag gtatcttcgg tagattcgag ttcaatatcg attgttccac catacactcc
     2821 ggaagagggt cttccttttg catctacatc acggtttaga gaataggcac agtgaagcac
     2881 atcgtactcc ttgcccgaaa agtttaatct tgctttgaaa gccataactt tttgttttag
     2941 ggttgtaaaa tattaactat ccggatggca tcaaaaattc tgccactaac aactaataat
     3001 caagtgcata caagataccg gatcagaaaa ctgcattttt aagatagcca gggcttaaac
     3061 ttaaaagcaa aaacattata aatattttca accttaatct ctcaggctgt aaaattatta
     3121 taatgtcacc gcaaacgtct gttttagtgt acgttccatt ttatagacaa gctgtttaaa
     3181 ttcaggtacg gagcaataac tgttcgaata ctattatttc tttttaacgt aactaaattc
     3241 ttacaaagaa aacataaccc ataaaaacgt gtattcaata cactagatgc cttatacgcc
     3301 tttaaatatc aagaagttgc cacaaactga taatttcact cttacctatc attatactat
     3361 attagtttag ctaaaccgac aaagctaaat caacctacta accagatatg aacaaaaaac
     3421 atttattaac cttagcaggc ttattattgg tcagccttcc cgcaacctta cacgcacaaa
     3481 atcagaaatg gcagaacctc tttaacggaa aagacctgac aggttggaaa caacttaacg
     3541 gacaggccaa atacgaagta actaatggcg aaattgtagg cacaactgtc tctaacaccc
     3601 cgaactcctt ccttgcaacc gcaaagaatt atagtgactt tattctcgaa ctggaactga
     3661 aagtagataa ctccatgaat tctggtgttc aagtcagaag tgaaagcaat gccgaatatc
     3721 aaaatggaag agtgcacggt tatcaggttg aagttgatcc ttctgaccgt aaattttccg
     3781 gaggtattta cgatgaggca agaagaggct ggttatatcc gctggacatt aatcccaaag
     3841 gccaacaagc atttaaaaat gagcagtgga ataaataccg tatcgaatgt ataggaaatt
     3901 ctatacgtac ctggattaac ggcgttccta ctgctaatgt gatagacgca ctcactccta
     3961 ctggctttat cgcgctgcaa gtacatgcaa ttggtaaaga tgaccagcct ggcaaacaaa
     4021 tccactggcg taatatccgc atacagactg aacaactcaa gccgtcaaaa gctgatgata
     4081 tttacgttgt gaacctggtt ccgaatacag tatctcccca ggaaaaagca gaaggctata
     4141 gcttgctgtg ggatggaaaa acgaatacag gatggaaagg tgcttacaaa gcaaccttcc
     4201 ctgaaagtgg ctgggtcatt aaagatggag aattaagcgt tcagaaatct aatggtgcag
     4261 aagctaccaa tggcggtgat attgtaactg aaaaacaata tggcgctttt gagctgaagt
     4321 tcgatttcaa gttaaccgaa ggtgcaaata gcggtgttaa atatttcgta acgcttaccg
     4381 aaggaaataa aggctctgca attggccctg aatatcagat attagatgac gaaaggcatc
     4441 ctgatgcgaa actgggaaag aatggtaaca ggacattagg ttctttatat gacttgatta
     4501 ccagtaaaaa gattcccaat gcacaacgaa aaatcggaga atggaacagc ggtttgatca
     4561 gggtctatcc caataataaa atagaatatt ggttaaatgg ctataaaatt ctggaatatg
     4621 taagaggatc tgcagatttc cttgctttgg tagcggatag taaatacaag gactggaaaa
     4681 actttgggat ggcaccaaaa ggtcatatcc ttttacagga tcacggtgac caggtgtttt
     4741 ttagaagtat caaattaaaa caactttaaa tccctccagc tatgttatca tcaagaagaa
     4801 aattcattaa gcaaactgca attgctgccg cgggaaccta tatgggaacg atgggcttat
     4861 ctgctaaaag ttatggaaac atcattggcg cgaatgatcg tgtcagagtt ggtgtagttg
     4921 gtttctcaga ccgctttgcc acttcactct tccccagctt tctcaaccat tacaaagagt
     4981 tgaattttga tattgttgcg gtatcagatc tatggaacta tcgcagagga ttaggtgaaa
     5041 actttttaaa agccaaatta ggacatgaca ttacggcttg tcgcaataac gatgaattat
     5101 atcagctgaa agatctcgac gccgtgattg taagcacggc cgatttccag catgctgttc
     5161 atgcaataga agctatcaat gccaaatgtg atgtttattg tgaaaagcct tttgcagaaa
     5221 ctatgtctga tgcccgtgca actctaaaag cggtgaaagc ttctcagcag attcttcaga
     5281 ttggttccca aagaagaagc ggtgctaatt atatagcagc tgaacagttt atcaaatccg
     5341 gcaagttcgg tgatattact atggttgaat tgagctggaa tgttaatcag ccaggacgtt
     5401 ggcgcagacc agatctggta gctaaattaa aacaagaaga tacagattgg aaacgctttt
     5461 taatcaaccg tccatttgaa gaatgggatc cgcgtatata cctggaatat cgtttattct
     5521 ggccgtattc atcagggatg cccggacaat ggatgtctca ccagattgat acggtacact
     5581 ggtttacagg gttgaaacat ccacgtagtg tcgtggctaa tggcggaatc taccaatgga
     5641 aagatggacg acggaactgg gataccacta cagcggtatt tgattatggc caggaaaata
     5701 atcctgagaa tggttttcag gttgtcttca cctcccgcat gcataacggc gatgaaaacc
     5761 cagcggaaat ttattattca aatggtggtg aattgaacct gaatacaaac ctggtttctt
     5821 ctaaaggagg tcttaaagct gatgctgcga atgcgatgca tatgcagcca aatctgttac
     5881 cagaattgaa actgactaat gtgacggaga aagtagctgc ttctgcaaat accggaggcg
     5941 acaaattaac ttctgcccac atgcgaaact ggatggaatg tatcagatcc cgcaaagaac
     6001 ctcatgcgcc tgtagaagta ggttattatc actctattgc caacattatg actaacgcag
     6061 ctgtcagaac cggtaagaaa gctgtctttg atgaagccac tcaggaggtt atggtggatg
     6121 gtaaagtttt caaatattaa ttcctgctta cgctacttta actaagttct ttatcaaacc
     6181 atcattaaac tttaactaat cgctcttaat aatactcgag tctggtctgt ttccgtatta
     6241 attgcagacc agatttcatc agataaatct tcatcaataa ccggttttct tcgtccatta
     6301 tcctcagcga atattgcaca aacaaaaccc agattaccag gacatgccgg agctgtactt
     6361 ccaatcaaag tatagctatc tggattaaaa ggatttgccc gagaagcttt tatataccaa
     6421 tctgccataa tacattatac ttcttttatg aatcaaaaaa caacaaaaac tttattccca
     6481 gcctactcta aaagttttca gcttctcccc ttacgcatta ctttagcaat ccatcaaaac
     6541 agcttttatc agagtcaaaa gcaacattaa aatttccata gcaattacta ttatatagca
     6601 accaagttcc gaagaaatca gacagcaaaa cagggccaaa agccccaaag agcaatcctg
     6661 caaaaacgaa aaactgtctt tcaccaatat aatccgtact actaaaagac agctctgaaa
     6721 gaaattccca aacctacaaa cgagaaatat tcatcagtaa atataccctc cgaaaaaatc
     6781 agctatttac aatagcgatt tcagcgcccc ttaaaatcaa tattcacctt ggtataaata
     6841 tcagcaggat gccaggtaaa gtaataagtc aacaatccag atacagagcc aatcaatgca
     6901 ccagccatga catcaggtaa aaaatggtgt gcaagataga tcctggaata acccgcaaat
     6961 aaagcgagga acaaacacaa aatactaacc cgtttatctt tgaaatataa ggcaatcact
     7021 atgcacatag caaaagctga agcagaatgg ccggaaggaa aagatgcaga ctgcattttc
     7081 tgtattccta ttacaaaata tgaatacttg aatcctatct gatcaaaata aagggatggc
     7141 cttggctcat ggagcaattt ctttagaatc tgaacgataa gccctgaacc caaaaaagcc
     7201 agtaataaag ccagggacaa cttctttctc tttagaaaaa gtagaacaat aatggtgagg
     7261 agacacatga gcccatctcc tataaaagta taataagaaa aaaacacatc cagaaatggg
     7321 cgatgataga aatttagaaa gttgaaacta gtaagtttag atgttaaagc acaagaaatc
     7381 agcccaatca tcaatataga aaccagaacg gcaaaaaata aagggcagtg ttttacagct
     7441 ttccatatca tataagctat acgcatccat aataccaaac ccctatcaac tcgcttaaca
     7501 ttaaatttat tttagcactt ttagctataa accatcattt attcaaccaa aaccagatga
     7561 aagttcatta tgtttgtcta gatttaacaa aataaattta gacaaacata atgaactact
     7621 ctatttctga tcttgaacaa ttatcgggcg tacaagtcca cacgatcaga atctgggaac
     7681 gaagatataa tgcactggaa cccatgcgtt cagcaggaaa tacacgcatg tacaatgagg
     7741 atcatctgaa aagattactg aatattgtca gcattagtca aaccgggctg aaaatatctc
     7801 aagtctgcgc cctctctgaa aaggaaatga atgatttcct taaaaaagaa atagagcaga
     7861 caatctcaaa cgatgcacat tttgaatact atacttctca gcttttaaaa tgcggattga
     7921 tttataacga gtccgaattt gatcacctca ttaataaatg tattctcgaa aatggaatga
     7981 tcatcactta ccagcaggta atttatcccc tgttagtgag attagggctc atgtggagga
     8041 aagatgatat ctgtcctgca caagaacatt ttttatccaa tatgatcagg caaaagcttt
     8101 atgcagctat taatgagctt ccagctgtta cccaagtaaa atcatcatgg ttactttttt
     8161 tgccagaagc cgaaggccac gatatcggac tcttgtttgc taattatata ctcaaacaag
     8221 caggacaaaa agtaatttat ctcggcggca gagttccatt ggactccgta aaaaacgcga
     8281 tgcaaaacaa gcaaatcaaa catatgttat tgtttatggt acgcattcaa ccattagagt
     8341 tagcaaatag ctatcttaat gaattaagta caacttatcc tgaaaccaga attcatcttg
     8401 ctggtaatgg aaaactaatt aatgaactga aaatgggtaa aaacataaat tggtttcagt
     8461 caataaatga atttcaacaa acgatcaaaa gcgtctcaaa tgcgaactaa aacagctcag
     8521 caaacaccaa gaatagcagt tataggtgcc ggatttgcag gtatcagtgc tgcagcttat
     8581 cttgccaaga acggttataa ggttgatgta tatgaaaaaa acagttccgt tggtggcaga
     8641 gcgcggcaat tagagactga aaacggatac gtttttgata tggggccaag ctggtattgg
     8701 atgccagatg tctttgagaa attctttaat gattttggtc atcaagccaa agacttttat
     8761 gaactggaac ttttagaccc tggtttctcc gttgtttatg gtcaaaatga tgttctcgat
     8821 attccagcag attttaacgc actctgtgaa acttttgaag ctattgaacc tggaagtgcc
     8881 ataaaacttc agcaattttt agaagaagcc gcttataaat ataaaaccgg aattgaaaag
     8941 ctagtttata aaccaggcct ctctttgatg gaattcgcag atatggatct cattaaaggt
     9001 gtctttaaac tacaagtatt tacctctttc agcagccacg taaaaaaata ttttaagcat
     9061 ccgaaactca tcgcactgat ggaatttccg gttttatttt tgggtgcaac ccctgaagat
     9121 actcctgcat tatatagttt aatgaattat gcaggcctga aattgggtac atggtaccct
     9181 aaaggtggat ttggaaaagt aattgaggcg atgaaaaccg tcgcagaaaa gaatggtgta
     9241 aaattccatt taaacgaacc tgtttctgcc ttagaaatcg aagggaaaga aatcaaagca
     9301 ctgagctctt ccaaacaaac aaaggcgtat gacggataca ttgctgccgc tgattatcat
     9361 catgtagaag aaaaactact tggcgaaaat tatagaaatt accaggagaa atattgggat
     9421 aaacgtgttc ttgctccttc ttgccttatt ttttatttag gcgtaaccag aaaaacagaa
     9481 cgcttaggtc atcatacgtt attttttgat gaagatctga aacagcatgc tattgaaatt
     9541 tataaagaac cacaatggcc gtctaaacct ttattttatg tttgctgccc atccagaacc
     9601 gataccactg tagcgccgga tggacatgaa aacttattcg tattgatgcc attggcgacc
     9661 aatatggaag ataccgaggc acaaagggag aaatatttcg agcttattat gaatcgcctg
     9721 gaaacttata ccggcgttga aatccgcaaa catctgaatt acaaaaacag ttactgtgta
     9781 gcagacttta agctggatta caactcttat aagggcaatg cctatggttt agccaataca
     9841 ttaatgcaaa ccgccaacct gaagccttct ttaaaaaaca aaaaggtcaa aaatctgttc
     9901 tatgcaggcc agcttactgt tcctggccca ggcgttcctc catctattat ttcaggccat
     9961 gtagctgcca gtcaactgat aaaatacttt aataaaaact atgaaagaga tatttgatcg
    10021 gttatctgca gagtgcagta agatcacaac caagcgttac agtacgagtt tctccctggg
    10081 tatctatttt ttagggaaga aattacgtaa tccaatttat tcgatttacg gattcgtacg
    10141 ccttgcagac gaaattgtag atagtttcca tgactttgat aagcactttc tgcttgcaaa
    10201 attcagacag gactgctatg aagctattga acataaaatc agtctgaacc cgatattaaa
    10261 ttcttttcag caagtggtta atgagtatgc aattgataaa gagctgattg agctgttttt
    10321 aaagagcatg gccatggatc ttgataaaaa gcaatattcc cctgaaatgt ataatcagta
    10381 cattttaggg tcagcagagg tagttggatt gatgtgcctt aatgttttta cagaagggga
    10441 taaagtacaa tatgaaagac taaaagattc agcgatgaaa ttaggatcag catttcagaa
    10501 agttaacttt ctcagggata tcaatgcaga ttatttcaac ctgagccgca cttattttcc
    10561 aaatattgat cttactatat tctcaaatca tgaaaaacaa attattgaaa aggaaataga
    10621 agaagaattt aagcaagcgc tcgctgggat taaacaatta cctgcttcct ctaaaaatgg
    10681 tgtttatctt gcctatatct attataaaga actatttaat aagataaaag gtacaacagc
    10741 agaaaaagta atgtccaaaa gaatccggat ttccaacagc cataaatttg gcctgatgtg
    10801 tgattcaatc attcgttaca aaatgaatgc gatatgaaaa cgctgaccct ttttatactt
    10861 tttatgtatg ggagtcattc ctatccggaa attacagaat tgcgcacttt atattatgaa
    10921 tcagcaaatg ataaagcagc agcaggtaaa cttcttgatt tactttccaa tgtggatgat
    10981 caatccagtc aacttttgat ttgctataaa ggagttgccg aaatgatgca ggctaaatat
    11041 acgatgagcc ctatttcaaa attcaggaga tttaagaaag gcaaagaata cattgaaagt
    11101 gcagttgcta ttgacccgga aaacttggaa atcaggtttt taagatttac aattcagaca
    11161 aaccttccct cttttcttgg ctacaacgac catatcatag cagataaaac gatattaata
    11221 aaaaatttgg atcagataca tgacaagcca ttcaaacaat tggtaattaa ctatttgttt
    11281 gcctctaaaa acatgactga aaaagaacgt aatagcataa aaaaatgaaa gatcacgtaa
    11341 tacttgtgga tcagattgat caggagacag gattgatgga gaaaatggaa gcacaccagc
    11401 gagggaaact tcatcgtgca ttttcggtat ttattttcaa tcagaagggt gaattcctat
    11461 tgcaacaaag agcactagag aaataccatt caggcggtca atggagcaat acttgctgta
    11521 gccaccccta tcctggcgag gatacagcga ctggagctaa aagaaggttg caagaggaaa
    11581 tgggtatgga ctgtgagttg gaatttggat ttagttttat ctattacgct gagctgaagg
    11641 atggtctttc agaaaatgag tttgatcatg tttattttgg catcagcaac acaattcctg
    11701 tacccaatcc agatgaagta gccgctttca aatacgtaac tttagaaacg ctggaaacgc
    11761 agttaaaaac aaacccggag cattatacaa tatggttaaa gatttgcttt gaccgcgtca
    11821 aaagtcatta taatcaactg ttcaacttat gagtaactgg ataattaaca ccttaattgt
    11881 agcggcaact ttcattggta tggaaggagt cgcatggttc acgcacaaat atgtgatgca
    11941 cggcttattc tggaacttac accgtgacca tcaccataaa gatcatgaag gctttttaga
    12001 aagaaatgac tttttctttc ttattttcgc tattccaggg attatttgcc tgggcctagg
    12061 atctttttac gggaatacaa ttgcgcttta tataggcata ggaattactt tatatggtgc
    12121 tgcatacttt tttatccatg atatttttat ccatcagcgg tttaaaatat tcaggaaatc
    12181 agaccactgg tattttaaag caatcagaag ggcccacaag atgcaccata aacatatcaa
    12241 taaagaacat ggagaatgtt tcggaatgtt atgggtacca tttaaatact tctttgaaaa
    12301 caataaaaaa actgaagcat gaaatacgcg tatctcctga ttgatttttt cacgatcagt
    12361 gtccctttca tttattcttt ccatccaaaa ttaaatttct acaagacctg gaaagccttt
    12421 tttcctgcag tatttttaac cggaatgatg ttcttaatct gggatgtata ttttaccagc
    12481 ctgggtgtgt gggggtttaa tcctgattat ctgattggtt taaaagtagg caacatgcct
    12541 atagaagaaa ttctattctt cttttgcatt ccctatgcct gtgtatttac ttttcattgc
    12601 ctggatcttt tcattaaaaa accgatcccg ctacgcattg aaaaaatcct gacaccctta
    12661 ctcatcctga tttgtgtcct gatgtcaatt ttataccgca atcatattta tcctgcagct
    12721 acatttttat tattagccgc tgtgcttaca ttgagcaggt atattttaaa aattggctgg
    12781 ctgccaaagt tttacatcat ttatacggta ttgctatttc cctttttaat cgtcaacggt
    12841 ttactgacag gaaccggatt ggatgcacca atagtttggt atgataataa ccagattatt
    12901 ggcttcagaa tattaagcat ccccatagaa gatgtgtttt atgggatggc actcatatta
    12961 gtcaacttgt taatttataa gcacctgctt agtcgccgtt ctgccgctca atagcttact
    13021 tgattcttat caaaaaacag gtaaactgcc tatatactag ctgggttgtg gctaggtact
    13081 ggtatacatt gaagtagcat tgaagtaggg ttgaactagc attgaagtag cctgggctac
    13141 ttgcacggtt cttcaatgct agttcaaccc tacttcaatg tgtaccacaa cccctacagt
    13201 acctggccaa atcccctcgc attcttatac tgaaattact tgatgtcatg ttttaactaa
    13261 gctggcaaaa accgaaaaat tactgaaaca atttattgtt ttgtgagtct tatcctaaac
    13321 ccagaacatg agcactttca aaaaatctgc aatcaattta ttcgcgatta ccatcctgct
    13381 cgtatcgacg cagaaaacca atgcacaaac cactaaatct gctcaactgg attccctggt
    13441 tcatcaggca aaccatctcg gcctgtttaa tggtaatatc ctgattgcag aaaataataa
    13501 agtgatttac aaaaacgctg ttggctttgc agatgcagca ggaaaaatca agttaactga
    13561 acagtaccgg tttcatatcg gctctatcgc caaagaattt aatgcagttg gaatcatgat
    13621 cctaaaagaa cagggaaatt taagcctgga agatcctgtt tcgaaatacc tgcctgaact
    13681 gccagcatgg gcttcaaaaa ttcatatcat caatttattg caatacacaa gcggcatccc
    13741 ggatgtaaaa tggaagtccg ttaaaagtaa cgcagataat atggaagacc tgaagaaaac
    13801 aacacggctt gactttgaac ctggtaccca gtatgcgtat aacaacaaca atgtttttct
    13861 gcaaagaagg atcattgaaa aaattaccgg tttatcattt acagccttta ccgaaaaata
    13921 catattaaaa ccttgcagga tgaagacagc gattgtagat ccggtagcta ctgataaatt
    13981 tattgccaga gcctacaaca acgatcatgc agaagatgag ctcacctatc caattaatgg
    14041 ttgggtcgca gttacgctag taagattttt ataaatgggc caatgcaatt acaaatttta
    14101 aactgatcag tccagcttcc accaaacaaa ttctggaacc tgccggtcct aatcagcaag
    14161 ctggtttagg tggtggtatg ctggaagcta accgggtcat cacccacaaa cacgacggta
    14221 ctgcaagaaa ttaccaggcc ctgctggtaa gcactgtttc aaaaggcaga accgtgattc
    14281 tgatgacaaa caatcagcag aacaatttat acaccttcaa cgtctctatt caggcaattc
    14341 tggacgaaaa accctatact caaattaaaa aatcagtatt gggcaccttt ggtaaacaaa
    14401 tagatcagct gaatggtaca gaggttatta cgttctatga aaagatgaag aaagaacata
    14461 atgatgaata tagttttgat gcagaagcga cactgaatga aatcggctat aattttttac
    14521 gccaaaaaaa attcacggat gccattttga tctttgaaca caatacaaag cttttccctg
    14581 agtcaggtaa tgtatttgat agtttaggag aagcttacta taaacaaggg gataaaagca
    14641 aagccttatt gaattataaa aaatcaattg tattaaatcc tgaaaatgga gatgcaaaaa
    14701 agattattgc agaactcagc tccaaatttt aacttgagtt aaaattcatc cttcttttcg
    14761 cactattaca tcatatcact tcttacttag gcatttaaac tctttcgctg aatagaatca
    14821 gaaagataat aatgcttaag taaaattgca aaatcctttt aaactacaaa ttatttgatt
    14881 tcgatgtaac ttattgccct tcatggtatc ttatttacaa ataataacaa ccatgaaacc
    14941 acttttacta accactctcc tattcttatt ttattttatt cccaatacct tacacgcaca
    15001 gcaaactgtt aaaattaacg gtactgtaat agatggtaaa caaacattac ctgctgcaac
    15061 agttttactg tatacagcta aagattctgc cctggtaact actgccatga ctgaccagga
    15121 tggaaaattc aatttcacag cagctccaag caaatattat atcgtatcct catccatagg
    15181 ttataacaaa gttaagactg cccctttcca attgaccggc cccgcagctt tgcagatccc
    15241 tgcaattaca ttaaaagaga attcaaaaaa cctgaacgaa gttagcatta cagcagctaa
    15301 accggtttta gaacgcaaag cagacaaatt gatctttaat gtagacgcga caccatcagc
    15361 agccggctta acagcgctcg aagttttaaa aaaagcgccg ggagtaaatg tagattataa
    15421 tgagaacatt tctctttctg gaaaaagcaa tgttttggtt acgatcgatg gtaaacaaac
    15481 ctacctgagt tcgacggaag tcgttaacct gctgaaatca atgcagagca atcagataga
    15541 aagcattgaa attatcaata atccaggttc cagatacgat gccaacagta ccggaggaat
    15601 tatcaatatc aaaaccaaga aaagcaatac agaaggcttc aacggaagtg tggcattagg
    15661 tgccggattc aacaaatacc tgcttcctaa tggctctata aacctgaatt atcgtaaaaa
    15721 agacttcaat gttttcggtt cttatggcta taacagaaat aagtctcttc aaacgctcaa
    15781 aattgatcgt ataacacctg gtacaaatcc attgtctttt agtcagcgga acaaagacac
    15841 ctctgtttat tcatcccaaa actttaaaat cgggactgac ttctttttat ccccgaaaca
    15901 cacgattgga tttttggtta agggaaatat tagtgattat aatcagcaaa gtttaagtat
    15961 ggtgaatatc ggcaaatcat ttgcggcaac agattcagtt ttaaaaacgc ctagttataa
    16021 ttcatccaac cgcaaaaatt tctcttataa tatcaactat aaaggagtat tggatactgc
    16081 aggacaggaa ataactgtag atgcagatta ttcaactttt gatggaacta acaatgcgaa
    16141 ctacactaac cgcttttatc tgccaaatgg aactttcttt aaagatggtc agatttatag
    16201 aaattttgca ccttctaaca ttgacatcaa agctataaaa gcagattata ctttacccat
    16261 caataaaatg ttcaagttgg aagctggtac taaaattgcc agtgtaaaga gtgacaacaa
    16321 ttatatttat gagaatgaca ttaaaggaaa ctgggttttt gataatacca aaagtaacag
    16381 gttcttatat gacgagaagg taagtgccgc ttatgcgact ttatatgtta cacttggaaa
    16441 aacatcttta tctggaggat tacgtgctga aaacaccaat tctacaggga attctatcac
    16501 tacaaaccag ttaacaaata gaaaatacac agacctgttc ccctctttgt ctttaagtca
    16561 gaatattgat gcagataaca ctttaaattt ctcttactcc agaaaaataa acagaccaaa
    16621 ttatcagaat ttaaatccct ttgtgttttt cctggatcaa tatacttata accaaggtaa
    16681 tcctaattta aaaccagaat attcgaataa cctggaagcc agttacctgt tcaaacaaaa
    16741 atatagcctt gctttgaatt acagtcgtac tacagatgta attacgcagg tattattgca
    16801 aaatgaagtt agaaaatcaa tgtatcagac catcttgaat cttgcttcag aaagcgtagt
    16861 ttcattgaca ttcaatttcc cggtaacagt tactaaatgg tggaatatga acaataatgt
    16921 actggggtat ttcaaacaga ttaaagcacc tgacttaaac ggtgctgatc tgaattcgaa
    16981 acaattcagc ggtaatttct atgcacaaaa taatttcaca ttgagcaaat tgtttagtgc
    17041 tgatgctgga ttaatgttta gcacaccaca aattgaaggt gcctttaaag tgaagagtat
    17101 gtacaatgct gatgctggat tacgctataa ctttcccaat aaaacaggga atctgaaatt
    17161 aggggtaaat gatattttcc attcacaaaa ggccaggata ttcagtaccc tgccaggcaa
    17221 tgtttataac ctggagcaat atggcaatac cacaagtgta agattaacct ttacttaccg
    17281 attcgggaaa atgaccgtaa aatctgcaag aaacagatca actggtcttg atgacgaaca
    17341 aaaaagactt ggtggaaaat aagcagaatt ttcaggaata tagaaatctt ctgttatgga
    17401 atcgcctcac gctaattcca taacagaaga ttgaaattat caggtagtgg atttcacagc
    17461 atctaaaact gttccgatat ttttgtgtga acttgcagga aattccgaaa tcaatttatt
    17521 actcttgaaa tttctaaagt tgtatttctt ttcttccgcg ttaaatgcag catcatgatg
    17581 atccagcgca gctgcatctt ctgcactaaa tcccttttta acttctttat gcccctttac
    17641 gactaaagta tctccttcaa ttctaactac tttcattaaa gtaacctgcg gttctgtcat
    17701 ctctggtgaa ggcattaaaa atactctaag tacatcaccc ggggctacag cgacaagtga
    17761 ggcagctctg gcttcactgg caacagcagc tttttcagct ctgttcttat tcaggattgg
    17821 tccaatcact gccagcccga taaaaacccc tgcaataata aagatattct ggaaaagtcc
    17881 ccaggcaaat ggagtttctg cttttaaatt ctgagcttct gcttttaatt cttctgacca
    17941 ttcctttttc ggaatttcaa cattttgatt aagatcaatt gctctgacct gctgtcctcc
    18001 taatgggcca agcgggccga aaattgacat gtattgctgg tatacatcca gctgaacatc
    18061 gcttttactc cttgttaacg aatcagtttc tattaaaact gtcctggaat tgagcgtttt
    18121 ttccttaata tcgtagatta taaacatatc ttgcgcttaa acaaatatag tgccacttaa
    18181 ttttttaaat aattacgatg atcacgtttg taaagggtca gcatgcagga agcagtaggt
    18241 taatatatta ttcctgcggt actgtaattg tatatcttat catttctctc ttgttaaaaa
    18301 tactgctgga aatcagtgct gaaacaacct gaccatcaac cagaatttcc atcttcacag
    18361 atccggcata ttcagcgata atacctaagg ataaaactgc tgatcttttg atagttgttt
    18421 tgaatttcct ggagaatggt aaggtttttt tatcagcaac agtgaccact ccagcttcat
    18481 cagtataaat aatatgccca cctgtaatga cattctgata agggctgatc ttatattcaa
    18541 ttgttacttc tttctgcgca taaaccggct gtcttccagt ttctttctta caggaaaaca
    18601 gcaaaacaag caatgcaaag atgaaagtta ttttacggct atgttgacca gttgtgtatt
    18661 tagtaaaaat gaaatagttc atgaatcaga tacgtgtgtt taatagtgta ttatttaaac
    18721 gcaatattga tcaatacccc cacgctaacc attatcaatg gtttatgaag ttacttcatt
    18781 aaacttttta ttccggtaat tgcaatctgt aatcctacgc aaaagattag aaatgcagaa
    18841 atacggttaa agattgcctc tgcattggag cccaggtaat gaataatgtt ttttgtattc
    18901 aaatagaaaa tataaatcag gatacacatc acaataatag cagataaaat agctgctgta
    18961 ttcatcaaat catcagagcg gtttgatgaa atgctatggg cacttaaggt gaacaggaca
    19021 gaaatagtac ctgctccagt agtgaccgga aaagtgatcg gataaaaaag ttgattttcg
    19081 atgtgactat atccggataa attagtttcc gcatccattg ttgaagttgt ttgtttttta
    19141 tcagaagaaa gattctccca ccccatttta caaatcataa tccctcccgc taactgcaca
    19201 accggaattg aaataccgaa taattcaagg atccactgcc ctgcaaataa agataccgta
    19261 cagattgaaa aagcatagaa agtaattttt ccaactgcct ttcttttttc agcagaactg
    19321 agcccggtaa aaaaagggct gataatgaaa gaagatccga tcgggtttac aactggaaac
    19381 aaggcgataa taccaataaa aagcaagtgg aaaaatgaat ggtataaaag aggcattata
    19441 aaattaggtt agttatcaat ttataatatg gaatatcagc attttccctg aagatttcag
    19501 taccctgctc ctgcaatatt tattatataa gctgtttatc aaggtaattt tggtcttggc
    19561 ttaggataag cgatagaagt tgctgtgttc atgaaaacaa aaacattatg catatttctt
    19621 ttatcaccac tggatatcaa caagataact cataagttca aataattttt gattactgat
    19681 tatattttat agatttggtg aaccaataat tggtaaacca aatatatcct tatgaaatca
    19741 tttatagaaa cgatcaagtc tattgaactt gaaactcctg tagataaaat aatcggacag
    19801 cttaaacagc taattacctc tggacaacta cagcctggtg accgtttacc tgctgaaaga
    19861 atacttgctg aaaaatttgg cgtaggccgt agttatgtac gtgaagctat tttgaaactg
    19921 gaattctatg gactgttaaa gaccaatcca caaagcggaa cttatgtagc tggcttgagc
    19981 atcaaagtgc tggacagcat catcaccgat atcatcaaat tcaataaaga agattttaat
    20041 gcattgcttg aagccaggta ttacctggaa ctggatgcgg tcaaattggc tgcagaaaga
    20101 agaacagaga aagatctgga aagcttaaaa gaagcattaa tggattatga agcgaaagtt
    20161 aatgcgaatc agaacgcagt agaggaagat atgattttcc atatccggat tgcaaaggct
    20221 tctaaaaact ccgtcattga atctatgatc ctgatcttaa tccccgatct gattaaaagt
    20281 attgtagaga ataaaatctg cggagataac agaggtaaac tggcgattga agaacacaga
    20341 aaaatcttaa aagcgattgt agatcaggat atcgatgccg cagaaaatgc agtggcagcg
    20401 catttaaatg atatgttcca attaagtaag gctgggtttg ctgcacaaaa aatcatacag
    20461 gacaaagttt aaaactacgc tcagaaaaat ggcataagcc ttaaaattta ttattcataa
    20521 tgatatgatg aactacttga aaaagttggt aatgggatta atttgcctga tttttggact
    20581 ctctgcttat gcgcaacagc atccttctat catgctgacc aaagataata taggggcgct
    20641 gaggaaaggg atttcaactt atcccctgct cggtaaatct tataagaaga tcaaatcaga
    20701 ggccgacaaa gccattaaag agccggttaa cgtacctgtt cctaaagatg caggaggtgg
    20761 tgcaactcat gagcaacata aaaagaatta cctcaacatc ttgaattgcg gaattgctta
    20821 tcaaatgtcc ggggacaaaa aatatgcagc ctatgtagaa gcattacttt taaaatatgc
    20881 ttccgagtat caaaaatggc cgcttcaccc taaaaggaaa gaaggtcatc agggtggcag
    20941 gatcttctgg cagagtttga atgattttgt ctggcaagtt tataccatac aagggtatga
    21001 tctggtttat gaggcaattg caccagctca acgtcagcaa atagaaaagg gcttatttgt
    21061 accagcagtt aaattcttca cggaagattg tgcggaaaca tttaataaaa tccataacca
    21121 tgccacctgg gcagttgcag ctgtaggaat gaccggttat gtgatcaaca agcctgaata
    21181 tgtagaaatg gcgctaaaag gaacagctaa ggatggtaag gcgggatacc ttgctcagat
    21241 tgaccaattg ttttcaccag acgggtatta cacagaagga ccttattatc agcgttatgc
    21301 gcttctgcct tttttgatat ttgcaaaaac gattaacaat tatcagcccg cacttaaaat
    21361 ctttcaatac cgtaagcaat tattagctaa agccattgaa acttcccttc agctcaccta
    21421 tacagatggt acattctttc catttaacga cgcggtaaaa ggaaaaacct atgaatctgc
    21481 cgaactggtt tacggcgttg atattgctta tgcggatatt aaatcacaac cagaattact
    21541 ggatatagtc cagaaacaag gccaggttat tatttctgat gccgggttaa aaattgctgc
    21601 tgatgtggct gcaggaaaaa ccaaaccgtt tgtttataag accctattaa ttactgacgg
    21661 tgcaactggt aaagatggtg gtattggaat tttacgggca ggaacaaatg aggaccagca
    21721 agctgtttta attaaagcca cttctcaggg tatgggccat gggcattttg acaggcttaa
    21781 cttattgtac gatgataata atgtggaagt attcccggat tatggttctg cacgtttcat
    21841 taacatagaa tctaaaaaag gtggtgacta cctgccagaa aataagtcat gggctaagca
    21901 aactattgca cacaatacgc tgacagtaga tgaaacttca aattttaaag ggaatgcgga
    21961 tcgtgcacag caaactgctg ctgaaattct ttacttcaaa gacgatcagg acctgaaggt
    22021 aatcagcgcg gcagaaaaca atgcttatcc gggggtaaaa atgacaagaa ctacagcttt
    22081 gctcaaagta gaagagctcc aaaagtcttt aatgatcgat gttttcagag ttgatgcaga
    22141 taaagcccat caatatgacc ttcctttttg gtataaaggg cacttgacag attcttctct
    22201 acagctcaaa tcttttgcgg atcagcttaa aactttgggc acgcaatacg gttaccagca
    22261 tatctggtta aatgccgagc aggccgttcc tgagcagaca ggttacctga cattgctaaa
    22321 taataaacgt ttttatacgg ttaatttcgc ggcacagtca cctgtaaacc tgaaattgct
    22381 aacgcttggt gctcatgatc cagatcagaa tttattggag agcaaggctt ttatgctttc
    22441 ttcaacaggc agtaaaacgc aaacgttttt tacagtgact gagacacatg gcagtacaaa
    22501 cacagtagac gaaaccactt ctggatcttc aagtagtgta agtgatttaa aaatcatcac
    22561 cgcagggccg gaacagattt cagtttcctt taaagtgaaa ggaaaactat atcactacca
    22621 gatcaacttc aaaaacaaag aaaactttat aaaagtaaac taatcaatat gttacagagc
    22681 aatttatttc aaatagaaga agaaacacct tggcaggatc tcggaaatgg agttaaaaga
    22741 caggtttttg gttacaatga tcagattatg cttgttaaag caaaatttga ggcagaagca
    22801 attggtcaat tacatcagca tcaccatgca caggtcactt atgtagacag cggggtcttt
    22861 gaaatgagta ttggtgaaga gaaaaagatt cttaaaaagg gtgacggttt ttatgcgcct
    22921 ccacacgaaa tgcacggttg cgtttgtctg gaagaaggtg tattgataga tgtattctct
    22981 ccacaccgcg aagatttttt ataagcttaa aagg
//
