LOCUS       NZ_CP014504            24207 bp    DNA     circular CON 03-MAR-2024
DEFINITION  Pedobacter cryoconitis strain PAMC 27485 chromosome, complete
            genome.
ACCESSION   NZ_CP014504
VERSION     NZ_CP014504.1
KEYWORDS    GSC:MIGS:2.1; RefSeq.
SOURCE      Pedobacter cryoconitis
  ORGANISM  Pedobacter cryoconitis
            Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
            Sphingobacteriaceae; Pedobacter.
REFERENCE   1  (bases 1 to 5950539)
  AUTHORS   Lee,J. and Kim,O.-S.
  TITLE     Complete genome sequence of Pedobacter cryoconitis PAMC 27485
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5950539)
  AUTHORS   Lee,J. and Kim,O.-S.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAR-2016) Division of Life Sciences, Korea Polar
            Research Institute, 26, Songdomirae-ro, Yeonsu-gu, Incheon 21990,
            South Korea
COMMENT     ##MIGS-Data-START##
            alt_elev                          :: 1 m
            assembly                          :: SMRT Analysis v2.3.0
            collection_date                   :: 2014.01.03
            country                           :: Antarctica
            depth                             :: 5-10 cm
            environment                       :: soil
            investigation_type                :: bacteria_archaea
            isol_growth_condt :: 0.1x Tryptic soy agar, celsius degree 20
            lat_lon                           :: 62.236389 S 58.71772199999998 W
            project_name :: Genome sequencing of Pedobacter cryoconitis PAMC
            27485
            sequencing_meth                   :: PacBio RS II sequencing
            geo_loc_name                      :: King George Island
            env_biome                         :: ENVO:01000186
            env_feature                       :: ENVO:00000097
            env_material                      :: ENVO:00001998
            ploidy                            :: haploid
            num_replicons                     :: 1
            ref_biomaterial                   :: not applicable
            source_mat_id                     :: PAMC 27485
            biotic_relationship               :: free living
            trophic_level                     :: chemoheterotroph
            rel_to_oxygen                     :: aerobic
            assembly_name                     :: ASM118778v1
            finishing_strategy :: complete; 110x coverage; 1 contig
            annot_source                      :: prodigal v2.6.1
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 110x
            Sequencing Technology :: PacBio RS II with P6-C4 chemistry
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 09:48:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,049
            CDSs (total)                      :: 4,958
            Genes (coding)                    :: 4,943
            CDSs (with protein)               :: 4,943
            Genes (RNA)                       :: 91
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 15
            CDSs (without protein)            :: 15
            Pseudo Genes (ambiguous residues) :: 0 of 15
            Pseudo Genes (frameshifted)       :: 3 of 15
            Pseudo Genes (incomplete)         :: 14 of 15
            Pseudo Genes (internal stop)      :: 2 of 15
            Pseudo Genes (multiple problems)  :: 3 of 15
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:50:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1670092
            Orig. end                         :: 1694299
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP014504.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24207
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="7"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24207
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24207
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14207](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14207)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            409..699
                     /locus_tag="AY601_RS07130"
                     /old_locus_tag="AY601_1447"
     CDS             409..699
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AY601_RS07130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AY601_1447"
                     /product="hypothetical protein"
                     /protein_id="WP_068398505.1"
                     /transl_table=11
                     /translation="MKKVLLIVMLAFAGTTFANAFTKSDFVNMITPIANNSYSLNELIS
                     TNAAIEYTSLENIQSNANRKLPHGDVTDEDGNVVGWWVYDGNSGVLLIYLY"
     misc_feature    448..461
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: weak, score: 15.87"
                     /tool="antismash"
     misc_feature    complement(733..746)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.48"
                     /tool="antismash"
     gene            769..3492
                     /locus_tag="AY601_RS07135"
                     /old_locus_tag="AY601_1448"
     CDS             769..3492
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AY601_RS07135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AY601_1448"
                     /product="hypothetical protein"
                     /protein_id="WP_157287763.1"
                     /transl_table=11
                     /translation="MKFLLFVILFLFFTPAKLFPQANKIISIKITNNGAAEKEPFDLYI
                     YADSTLKFKFLNSNTDTIFKISGKPGIVYHAVISRLGETVPIYNWKFDTLKVNFTKQLP
                     LDPVALHLKTVVINGQRQTYKRGDTLVIPVEDIRTRPHSSATELIDKIPGFSAGTNGNI
                     TALGKKVQKIRLDGAEIFGGNPRATLENIKADMLKDVEIINMDGDSGGGIELNLRLKKD
                     RKEGWYGEVYGQQGTSERNNAGVKLNKIKPGTNFSSFFNYNNQNQQVLSPNDYLKMISS
                     GNEIRNTLGTQKLYYDFKLEDPFDNINRVLEKLSFLEKGEHKTLSAGLNFSKTYKKISW
                     NSYLLGNYDKANIDDISNTTRSLGEFRAEDFKRYTNRNKAFDATQETSLKWTPNDKNTI
                     SAKLILERKYLKSAQSGQLNSSLYNQSDSLINKALIFTNQLPVNSNNLLLLTGNWEHRY
                     QKPAQKTTASAGMLLNKTIADNNYQNQLTTNADLLNNADNQVHQSNSNYNYFGTVQHST
                     SLSRKLLFDIRTNAMLSRSLTDRVGVNILEDKKVQPSLSLSTKNFIVQNNRITLQSFLF
                     YKSGPLSIVAGAGALSSHWKVAANDSLFNQINKTTFLPGFYANYVFNKSKVSFRYTKEQ
                     FTPALNNLLPAVDSSMIQQVSIGNSMLSPYLSNKYEINSDVFIQGLGSVNLQVNYALTN
                     LPITDNFNIINGGSFPERSFTQFGKAKEITGTLSYFRFNTSKSINPYVFLFYLWRKQYQ
                     LNQQVVTPLEFSAISPQAGLKINFSKEHNLNLSIQAIINNAHGTTGSSTVRYNMELKDD
                     NKLMEGLYYKVSTKWILINTDHTLSSINPIINFNIYKYFSKLKSWQVNIGASNLLNVNM
                     IKLLNAGITERTTASYNYLSRYVNIGVTFYPERWKK"
     gene            complement(3495..4640)
                     /locus_tag="AY601_RS07140"
                     /old_locus_tag="AY601_1449"
     CDS             complement(3495..4640)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008238539.1"
                     /locus_tag="AY601_RS07140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1449"
                     /product="hypothetical protein"
                     /protein_id="WP_068407278.1"
                     /transl_table=11
                     /translation="MMKKRYLFAVTILMVSSTSAFSQKTQLYIARNSVGKLQAAIANKQ
                     DQKAQLSILSEGIKAAEAAEKDRETKKWPETWAIKSYLSSYIAIVDPSQDNSDKYFDLA
                     INAIDSAKRFDKFEDNSGLIKASSYNINIKKQQKGKSAYQAKDFSAAFKYLKEVSDFFP
                     KDTILAVNAALSAEGVKNEDEALAYFKRAKENGIMNAVVFQRMADIYKRKLDNELALKT
                     LQEGLIYNPYNDLLNNDYINLLLDTEKYTEARQVIESTLKVETRSKLLYYLYGYLHQKN
                     TNMGTAELAYNKALDIDRNYFDALYQLGLVYLNLSNDALATPKKDLLAFTSNLNRAEII
                     LSQAHKVNRKDKPTITLLIDIYTRKNRFDRAQELKAQLEEF"
     gene            complement(4730..5830)
                     /locus_tag="AY601_RS07145"
                     /old_locus_tag="AY601_1450"
     CDS             complement(4730..5830)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1272: TPR
                     repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015807981.1"
                     /locus_tag="AY601_RS07145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1450"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_068398512.1"
                     /transl_table=11
                     /translation="MKKVVLSMLLIGAATYANAQKSEVSKAKNTWALASLPGAKTLDET
                     LKSLEDGLKTTDNAIANEKSKIMPEAWSYRALFASRISFVDSLNIANAVAKDKIAEEAI
                     AKAKELDTKGSEKDNIKEAEQTLSNALRNRAIFAYNKKDFKSALQFFNELTVKNPQDTS
                     TFVNAGVTAKQINDYPEMVKNFKKAIDLGSKDSESLYSEIISTEFSQVKDTVAGTALLE
                     AALAKYPENSYFSGMQTDLYIKQGNVAKAQESLAKLIAKDGKNASYQYAMGDTYYKQAL
                     DLQGKRNKIDPKKKKEFDEVTLKMKGFIDQALPYYKKAYELDPKMVSALENLKVIYAFK
                     DDKVNYEATKKLLDAQNGTPAAAPKK"
     gene            complement(5936..8566)
                     /gene="gyrA"
                     /locus_tag="AY601_RS07150"
                     /old_locus_tag="AY601_1451"
     CDS             complement(5936..8566)
                     /EC_number="5.6.2.2"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA]"
                     /GO_function="GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006259 - DNA metabolic process [Evidence
                     IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="gyrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016193680.1"
                     /locus_tag="AY601_RS07150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1451"
                     /product="DNA gyrase subunit A"
                     /protein_id="WP_068398518.1"
                     /transl_table=11
                     /translation="MAEDLENQENDKIIKIDIDEQMKSAYIDYSMSVIVSRALPDVRDG
                     LKPVHRRVLYGMLDLGLANNRPYKKSARIVGEVLGKYHPHGDSSVYMTMVRMAQPWSLR
                     YLLVEGQGNYGSIDGDSPAAMRYTEARFQKIAEDMLADINKDTVDFQLNFDDSLKEPTV
                     LPAKVPNLLINGSSGIAVGMATNMPPHNITEVINATIAYIENTEITIPELMKFVKGPDF
                     PTGAIIYGYNGVSDAFETGRGRIVMRAKAEIETVKDRETIIVTEIPYQVNKAMMIERTA
                     ELVGEKKLEGISNIKDESNKDGIRIVYEIKRDANASIVLNNLFKQTALQTSFSVNNIAL
                     VNGRPQMLNLKDLIRHFVDHRHDVIVRRTKFELDEAQKRAHILEGLLIALDHLDEVIKL
                     IRASNTPEEARTGLMEQFGLSDIQARAILDMTLRRLTGLERDKIKEEFNELMKTIEYLQ
                     SILADEGLRMQIIKDELAEMMDKYGDERRTTIVHSAEDMSMEDFIEDEEVVITISHEGY
                     IKRTPATEYRTQARGGKGSKGSDSRNEDFIEHLLIASNHNYMLFFTETGRCFWLRVYEI
                     PEGSRLSKGRAIQNIINIPKEEKIKAYIKVKNLKDQEYLENNYIIMCTKKGTIKKTSLE
                     AYSRPRVNGINAININEGDQLLEASLTSGSSEIIMALRSGRAIRFNEATVRPMGRTATG
                     VRGVTLGHAADEVVGMIAVDDPSATVMVVSEKGYGKRTNVEDYRVTNRGGKGVKTITIT
                     DKTGDLIAIKAVTDADDLMIINKSGIVIRIVLSQLRVIGRATQGVRLINLKGNDSIASV
                     AKIEHEDDPEEEVNGELLLVDPADVLPEEGGAEEAETEEGAEEPEEEGSDEEGEAEDTD
                     ETEED"
     gene            complement(8665..9558)
                     /gene="hemF"
                     /locus_tag="AY601_RS07155"
                     /old_locus_tag="AY601_1452"
     CDS             complement(8665..9558)
                     /EC_number="1.3.3.3"
                     /GO_function="GO:0004109 - coproporphyrinogen oxidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="hemF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013631288.1"
                     /locus_tag="AY601_RS07155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1452"
                     /product="oxygen-dependent coproporphyrinogen oxidase"
                     /protein_id="WP_068398519.1"
                     /transl_table=11
                     /translation="MLKDKVVEAYQKIQDEICQALASADGGGQFEEEIWTREGGGGGRT
                     RIFQNGNVIEKGGVNFSAVYGKLPEAVKKAFKVENDEFFATGVSIVIHPSNPFVPIIHM
                     NIRYFEMDEQTRWFGGGIDLTPHYVIDEDVRFFHQLLKQTCDEFDASFYPKFKKQADDY
                     FFIKHRNEMRGVGGIFYDRLKPENTGLDWDQLFNFSLGVGNSFIPAYTELIERNRNTEF
                     TAAQQEWQYVRRSRYAEFNLVYDSGTKFGLETNGRIESILMSLPPMAKWIYNHQTTENS
                     AEAATLTKLIKGIDWA"
     gene            9821..10000
                     /locus_tag="AY601_RS07160"
                     /old_locus_tag="AY601_1453"
     CDS             9821..10000
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AY601_RS07160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AY601_1453"
                     /product="hypothetical protein"
                     /protein_id="WP_068398521.1"
                     /transl_table=11
                     /translation="MKEEKKQFKFSLNKKVISSMANSQPTNLGQGANQLVDSSTCQVQS
                     CHQCITVPIPTISF"
     CDS_motif       9821..9892
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKEEKKQFKFSLNKKVISSMANSQ"
                     /locus_tag="AY601_RS07160_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9893..10000
                     /prepeptide="core"
                     /locus_tag="AY601_RS07160_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-3.60"
                     /molecular_weight="3544.0"
                     /monoisotopic_mass="3541.8"
                     /core_sequence="PTNLGQGANQLVDSSTCQVQSCHQCITVPIPTISF"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKEEKKQFKFSLNKKVISSMANSQ"
                     /leader_location="[9820:9892](+)"
                     /alternative_weights="3562.0"
                     /alternative_weights="3580.0"
                     /alternative_weights="3598.0"
                     /alternative_weights="3616.0"
                     /alternative_weights="3634.1"
     gene            complement(10001..13054)
                     /locus_tag="AY601_RS07165"
                     /old_locus_tag="AY601_1454"
     CDS             complement(10001..13054)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="AY601_RS07165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1454"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_068398523.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.6e-112,
                     bitscore: 374.9, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.8e-38, bitscore:
                     130.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKYNFYNKLVLRTSLLPYTDIQAALLNSSYLENNIFLEALFISA
                     PELFELYLADPENEQIKLTISKYFLRASFRTTPFGLYAGMNVIDWSAGEKKTIGLHGFK
                     RVTKLDISCLDAICRSIMGNEMMKSVVKLYPNSSIYKVNNSYRYIEPHSLSQFQLSSFD
                     YSSISKTILNFCRDGKTFPQIVDYLTASYPGEENAIKDFLQEMISAGILVYALIPQLIG
                     TDPLEQIIVALEQTGTLHHSEEINSYVNDLKAITGLLSEIDIQRVQNRSNYLKLKQHIE
                     SVFGIKVPLHKLVNVSMFPAYTGGLDKSFQHPLIEGLEVLKILNHRPNKNPMLQEFIAK
                     FADRYETQQKPLLEILDQENGIGYSDISISGEIMNGLMKSIKPLAKDKTEQAWDAMSSY
                     LLNKVIESQRNREEEIRLEKSELLKLVNVEGDGFIQENLFVLFRVADERIFLESAGLHG
                     AINTITRFATIDDNIKEVAMAFSPPFDEQDQPIYAEISHYPDPIMGNVLIRPRLTRYQI
                     SIVYNSAIPAEDQIPVNDLLISLRGEVLVLHSKRLKREIIPILSSAHNFHHSRNLPVYK
                     FLCDLQLQQDKNSLLFQWPAALKGLVFFPRVVCRSSVLSLASWNFKDQDLALFIQDIKE
                     FQHTPFMKKWGVPRKFIVSDGDNELFADLNEESSRKVILQLLSKKSAVLIKELFLPVRD
                     TVVSGENGNTNQFTAFLKGKGNSIYTGEKTIANIPKVREFYPLSEWIYFKIYCGGTISD
                     EILVGTIDKLTNRLLKDKLIDKWFFIRYTDPGYHIRVRLAVKNKNDIPRITAQLNRCLE
                     ILISRKKAWKIQFDTYKPEIERYHTYGMDISETAFFLSSRYTLKLLAYLNRSIGSEQQV
                     LFLSMVSVDHILSAFNFETKEKLRLVGQFKKSMESGYKIDTDFWKKIDVQFKANKSGIA
                     ELMVLQPANGSEINKLLSNWKVELAELYKTAKATGPDLESYIFSLAHMQVNRLFKEHQK
                     INELITYQLLSKYYSLVLYSKNQAVISP"
     misc_feature    complement(13032..13045)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 24.68"
                     /tool="antismash"
     gene            complement(13059..14207)
                     /locus_tag="AY601_RS07170"
                     /old_locus_tag="AY601_1455"
     CDS             complement(13059..14207)
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="AY601_RS07170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1455"
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_068398526.1"
                     /sec_met_domain="LANC_like (E-value: 2e-39, bitscore:
                     133.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNKINEIAKILSENYSSLPRISVKDGRLGAALFLSSYSDFSGEG
                     QYNDLTEEIVSEILEDINSGYVSDTLGKEMADLGIFLSYMKDQDLLDISSDELLNDLDV
                     IADDFVDKNIEAQDFDPFTGFLAQGYYLLNRDTQVSRDAILKIVKAISFISIQDKDGHL
                     FWKSPKFSNGGIYTGITHGSCAIIQFLLKADLKFKFDDTIKKLIVNSIDFLLKHKLNFE
                     EYNFYFPTKIGEEVVKTPVEWCYGDLSIGYTLLNAGLHLKNELLEKTGIEILENTVKRT
                     DPQNYIDDASLSYGSAGIAIVLKKALLLCDSPVLQTAYHDFIDKTLKHAKSVNGFAGYQ
                     AFFYKDSTEINLGFMTGLSGIGLAFLAHMDEKYLPFTCFLYL"
     gene            complement(14371..14988)
                     /locus_tag="AY601_RS07175"
                     /old_locus_tag="AY601_1456"
     CDS             complement(14371..14988)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258647.1"
                     /locus_tag="AY601_RS07175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1456"
                     /product="fasciclin domain-containing protein"
                     /protein_id="WP_068398529.1"
                     /transl_table=11
                     /translation="MKKQIFTVAMALAFLSLASACNSSKPGSTTDTSTTTMTDTSSKMS
                     SMADTSKMSTQEGVMVGGALMVPSKNIVENAVESKDHTTLVAAVKAAGLAETLSGKGPF
                     TVFAPTNEAFDKLPAGTVAKLLKPEMKKDLAGVLTYHVVAGNYKAADLKDGLELTTVQG
                     QKIKFSKKDGQWYVNDAKITITDAVSSNGVTHVIDAVLMPKK"
     gene            15149..15634
                     /locus_tag="AY601_RS07180"
                     /old_locus_tag="AY601_1457"
     CDS             15149..15634
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008238530.1"
                     /locus_tag="AY601_RS07180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1457"
                     /product="DUF4442 domain-containing protein"
                     /protein_id="WP_068398533.1"
                     /transl_table=11
                     /translation="MIVSERTLKWGLCFYPPLLFQRIWVKKFHPGFRGADIKIYKSLFN
                     KNYNGSIFGGTIYAATDPFYALLFDQLLQRQGFKVRVWLKSASIQYLKPGRSALFFTII
                     ITDEMLNDAIEALNTSGKFVKAYPMEIKNSAGEVCATVMNEVYVRNLHSGENGPVAY"
     misc_feature    complement(15658..15672)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 24.01"
                     /tool="antismash"
     gene            15663..16295
                     /locus_tag="AY601_RS07185"
                     /old_locus_tag="AY601_1458"
     CDS             15663..16295
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014679743.1"
                     /locus_tag="AY601_RS07185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1458"
                     /product="ATP-binding protein"
                     /protein_id="WP_068398536.1"
                     /transl_table=11
                     /translation="MNIRKLILQGEGTTLDFKKTINNYEKIAKSLVAFANNKGGQLLIG
                     VADDGTIKGVKSEEEEKYMITRSAHQFCKPAIEPEFEEIYIDSKLVLVAKIPQSDTKPH
                     YALDENKKWWVYFRVNDKSILASKIIVDVLKKENTHSGQLITYTEQEQKLLKYLDQEGR
                     ITLKQFSKLTKISNQKAQRILVSFILADLIQPHSSEKEEYFTMTTPK"
     gene            16326..17690
                     /locus_tag="AY601_RS07190"
                     /old_locus_tag="AY601_1459"
     CDS             16326..17690
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013631292.1"
                     /locus_tag="AY601_RS07190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1459"
                     /product="MATE family efflux transporter"
                     /protein_id="WP_068398539.1"
                     /transl_table=11
                     /translation="MFSSFYAKYKPYYSDNLRLAMPIVVSQLGHTVVHLADSVIVGHFA
                     GTIQLAAVSLVNSLFMLILVLGMGISYGLTPLIAQENGRKNYKECGRLLSNSLLINIMI
                     GIFLYLLVHFGTLLVIDNLGQSPEVVAYAKPYLGYLSFSIIPLMIFQTFKQFAEGLGFT
                     KQAMFISIWGNIINVILGIILVKGMFGIAPMGVKGVGISTLVDRILMATVMCIYVFNSK
                     NFKIYLQNFKLTLIDKIRSLKILKIGAPVALQYSFEISAFSGAAILIGTIGAVEQAAHQ
                     VAINLASVTYMLASGIASAATIKTGNNLGKNNFLDLRRSAIASYHTVAVFMSITAVAFV
                     CANHLLPYIYTEDTAVINIAAQLLIIAGFFQLFDGTQVVGLGVLRGLGDVNIPTVITFV
                     AYWVIGIPLGYLLGITLEMGVNGIWYGLTFGLLTASVMLFFRFQKRTRMLVAVPA"
     gene            17789..18706
                     /locus_tag="AY601_RS07195"
                     /old_locus_tag="AY601_1460"
     CDS             17789..18706
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012781496.1"
                     /locus_tag="AY601_RS07195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1460"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_068398542.1"
                     /transl_table=11
                     /translation="MANQKASIYSALAANLLIAITKFIAGAFSNSASMISEGIHSVVDT
                     VNQLLLLFGLQRSKKPADALRPFGYGKELYFYSFIVSILIFGLGGGISIYQGIIHISNP
                     EPLGDPTWNYVVLALSVVFEGTSLIIAAKAFNKVRGHETWWNAIVKSKDPSSFLVLFED
                     GAAVLGLSIVMICMVIGHQFHIPQLDGVASLLVGLLLVGVSLILARESRSLLMGEGISA
                     ISRQKIVEKTEAVPGVVKVLTVVSTYQSPEEVLLMLIATFKEDLNTHQINEAIDAIQAG
                     IRREFPLIRYIIVQPEEFTKQFKF"
     misc_feature    17819..17834
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.62"
                     /tool="antismash"
     gene            complement(18868..21132)
                     /locus_tag="AY601_RS07200"
                     /old_locus_tag="AY601_1461"
     CDS             complement(18868..21132)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1272: TPR
                     repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF019339.4"
                     /locus_tag="AY601_RS07200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1461"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_068398544.1"
                     /transl_table=11
                     /translation="MTTIQDLQSLYNQGEFSKCLESLNPFLLVNPDSIEGLLLKARCEY
                     QSASQTFDPDTNDISLYITAYHSFEYVLKLQPTHEEAMLYAAYINIFVTQDNLPEAQVY
                     CDILVFSENEDTRLKAIGYRRQVNFILGNMELVLEDIDLMIAHYKALYPNNRSILDQEL
                     GLLYLEKTNIYLWHKEDALQVFQTFREGKAYPHQNYLTHNAVALLALDYQRLELAGEAA
                     FMAFTYSDEQPNQELIDLYHRINDLSAKSKLNKLLVYSLILALRRFSEHLKADPIEILS
                     LSLSYMKVYPDWDIPYHFAGTFLFDEKKYEEALPYLKKSLEIGGLARGLRRYIDANCRI
                     MGQLPDIESLPADSPEAYYAAGCDFYYESIPNIWTEGLSEELQEIKVKFYEISYQGFYE
                     YFYNNTGESLANEVHTFAMCCNNYGIALSEIGAFEKAAEVHAIGYSLSPFWEQLNSWGT
                     ALKGLEKYEQAIEIYEVAATYSSDYLSFSAYLRIKAEILDMTYKLGRNEQTYEILDSIT
                     EEYDSFLEINKKELTEAQLFELSEQYIIIQNVRHDLLSKGSPEDAIKAWQNELVKNPDD
                     NSAWFMLMQEYYIIKDYSQCIACADNYQSVKKEAIQDTSRCKIHYMRGLSYMNLGNYEK
                     AIEDLKALIAPLKIVYPDNEYELSRAYLHLADCYFILNKWDNCKESAYQGILCYIRNEW
                     AWDDELLKVKLQYADALYKTGSKGEALENIKNILEAYPANEEALKRRKEWKKGLFSFFK
                     S"
     misc_feature    complement(21238..21251)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.7"
                     /tool="antismash"
     gene            complement(21328..21852)
                     /locus_tag="AY601_RS07205"
                     /old_locus_tag="AY601_1462"
     CDS             complement(21328..21852)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.4"
                     /locus_tag="AY601_RS07205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1462"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_198163637.1"
                     /transl_table=11
                     /translation="MMSISKASISDLSALLNLVNTTYRGETSTKGWTSEILLLAGEIRI
                     DEEILTDYLTNPSISVLKFTNPANQLIGCVYLEQKEEHLYLGMLAVNPEFQDGGIGRLL
                     LHGAEEHARQLNCNKINITVIEDRTELIAWYQRRGYVTTGRKFPFPVEYHKYGKPLKEI
                     ILIEMEKKINF"
     gene            21984..22355
                     /locus_tag="AY601_RS07210"
                     /old_locus_tag="AY601_1463"
     CDS             21984..22355
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AY601_RS07210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AY601_1463"
                     /product="hypothetical protein"
                     /protein_id="WP_068398551.1"
                     /transl_table=11
                     /translation="MKKLIILLSMIMLFLQFTPFSQAVAKEKPAVKKDFRILKAILCNY
                     RLTPGGPGIAAPFATLINVTTGETTTTDATGHGGLRLKLMDTIVAKVNIPGQGWFSTTR
                     LYRLEQLGLTLLPDPNITD"
     gene            22514..23719
                     /locus_tag="AY601_RS07215"
                     /old_locus_tag="AY601_1464"
     CDS             22514..23719
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021523.4"
                     /locus_tag="AY601_RS07215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1464"
                     /product="DUF2252 family protein"
                     /protein_id="WP_084359141.1"
                     /transl_table=11
                     /translation="MSLSERIIASNKGMLAEMVQLKYQAMTESAFRFFRGTCEIFYQDL
                     SLWKAMPKSPLSWICGDLHVENFGSYKADDGQVYFDLNDFDEALLAPVAFELVRMLTSI
                     FLCFDFLELEDLKAMNMANVFLKNYSAVLARGKALAIEPRIAKGIICTFLMAVSKRKQS
                     RLLDKRTEVRKRKLVLSLEDERHFELDKDLRKDLVEHLTDWINNHSRSPYNYKVRDVVF
                     RLAGTGSVGTKRYMFLLENLLKKGKYLIVDMKQSQPSALTPYVKVSQPQWETEAERVVF
                     AQELSQHMPCSLLSHTVFKGDAFVVKEMQPAEDKIKFRLIQDQYRDIFQVIDDMAALTA
                     SAHIRSSGRKGSAIADELIEFGRSTAWQEKLIDYAFKYAQKVKKDFKVFKTGVDSGIYA
                     NS"
     gene            23779..23946
                     /locus_tag="AY601_RS26020"
     CDS             23779..23946
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AY601_RS26020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_232324712.1"
                     /transl_table=11
                     /translation="MIEDTFGMNIIPDNDSERLQALKRYRIMDSPSEASFDNIARLCTQ
                     IFNVPNSGPG"
     gene            23921..24130
                     /locus_tag="AY601_RS07220"
                     /old_locus_tag="AY601_1465"
     CDS             23921..24130
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="AY601_RS07220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AY601_1465"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_068398557.1"
                     /transl_table=11
                     /translation="MFLIQGQDKDKLFDRFYRVLNDDIVSGFGIGLYLCAEIIDRHQGK
                     IGVESEFGEGSTFWFSLPVAVVSV"
ORIGIN
        1 tatcaaattt ggtttcccac gttaatattt cagttttact ggatgaattg ccaatggctt
       61 gattatgatc aggtttttga ctgccatcaa ccgatatctg gctcccatta tcagtcttat
      121 tctcgatgac cgaaattagc ctatgccctt tataaccctc aaaatcaggt tttttgacct
      181 gcgactttgc agaggagaca aaaaataaaa aaactattaa attagtagcg tatattaatt
      241 ttcttttcat tctggtgata tttaattatg aatgcaatta tagtaaactt tatatttaat
      301 taacgcttgt aatgagaatt aaaatttctt atattaacct tcagttgatg atattagaat
      361 aaggcttata tcaaaaagaa ttaatttaac catttaaagc ttaaaatcat gaaaaaagtt
      421 ctcttaatcg ttatgttagc atttgcagga accacctttg ctaacgcgtt tacaaaatca
      481 gattttgtaa atatgattac ccctattgca aataatagct attcacttaa tgaattgata
      541 tcaacaaatg ctgctatcga atatacatct ttagaaaata ttcagtctaa tgctaaccga
      601 aaactgccac atggtgatgt aaccgatgaa gatggaaacg tagttggctg gtgggtttat
      661 gacggaaact ccggcgtact gcttatctat ctttattaaa aaataaatat cattaactgg
      721 atctaagcct tattttagtt aaaaatatca actcaaaccg gataaccttt gaaatttcta
      781 ttgttcgtta tattattcct gttttttact cctgcgaaac tattcccaca ggcaaataag
      841 ataatatcta ttaaaattac gaataacggc gctgctgaaa aagaaccatt tgatctctat
      901 atttacgccg actctacgct taagttcaaa tttctgaatt caaatacaga tacaatcttt
      961 aaaatatccg gaaaacccgg aatagtttac catgctgtaa tatccagatt aggagaaacc
     1021 gttcctattt ataactggaa atttgacacc ttaaaagtga attttactaa acagctgcca
     1081 ttggatcccg ttgctttaca tttaaaaaca gttgtgatca atggccagcg acaaacctat
     1141 aaacgcggtg acaccctggt catacctgta gaggatatca gaacaagacc gcattccagt
     1201 gccactgaat taatcgataa aattccggga ttttctgccg gcacaaacgg aaatattacc
     1261 gctctcggta aaaaggtgca gaaaatcagg ttagacgggg ccgaaatatt tggtggaaat
     1321 ccaagagcaa cactcgaaaa cattaaagca gacatgctta aggatgttga aatcattaat
     1381 atggatggag attccggagg aggcatcgag ctgaatctcc ggttgaaaaa agacaggaaa
     1441 gaaggatggt acggagaagt ttacggccag caaggaacca gtgaaagaaa taatgccgga
     1501 gttaagttga ataaaattaa acccggaacg aatttcagtt cttttttcaa ctataacaat
     1561 cagaatcagc aagtgctgtc cccaaatgat tatctcaaaa tgattagttc tggtaatgaa
     1621 atacggaata cccttggtac acagaaacta tactacgatt tcaaattaga agaccctttt
     1681 gacaatataa acagagtatt agaaaaacta tcttttttag agaaaggcga gcataaaaca
     1741 ttatcagcag gactcaattt tagtaaaaca tataaaaaaa taagctggaa ttcttatttg
     1801 cttggtaatt acgataaagc caatatcgat gacatttcaa acacaaccag gagcttagga
     1861 gaatttcgcg cagaagactt taagaggtat accaatagaa ataaggcttt tgatgctact
     1921 caggaaacca gtttgaaatg gactccaaac gacaaaaata caattagtgc caagttaatc
     1981 ctcgaaagaa aatatttgaa gtccgcgcag tccggccagc tcaatagttc tttatataac
     2041 caatcagaca gcctgatcaa taaagcgctg attttcacca atcagttgcc agtaaatagc
     2101 aataatttat tactgctcac cgggaattgg gaacacaggt accagaaacc agctcagaag
     2161 accacagctt cagctggtat gctgctcaat aaaacaatcg ctgataataa ttatcagaat
     2221 cagctgacaa ccaatgcaga ccttttaaat aatgctgata accaggttca ccagtccaac
     2281 agcaattata actattttgg tactgttcaa catagtacat cactcagtag aaaactctta
     2341 tttgatatca gaacgaatgc aatgctttcc cggagtttga cagatagagt tggcgtgaac
     2401 attttagaag ataaaaaagt gcaaccaagt ctatccttga gtacaaagaa ttttatagtt
     2461 caaaataacc ggattacact tcaaagtttc ctgttctata aatcaggtcc tttaagtatc
     2521 gttgccgggg ccggggcatt atcatcccat tggaaagtag cagcaaatga ctcgctattt
     2581 aaccaaatca acaaaactac attcttgcct ggtttttacg ctaattatgt ttttaacaaa
     2641 tccaaggtct ctttcaggta tacaaaagaa caatttacgc cagctttaaa taacctttta
     2701 ccagcagttg atagtagtat gatacaacag gtttcaattg ggaattcaat gttgagcccc
     2761 tatctctcca acaaatatga aatcaattca gatgttttta ttcaagggct cggctcagta
     2821 aatcttcagg taaattatgc tttaacaaat ctgccaataa ctgataactt caatataatt
     2881 aacgggggct cttttcctga acgaagtttt acccaatttg gaaaagcaaa agaaatcacc
     2941 ggaaccctat cctactttag attcaataca tcaaaatcaa tcaatcctta tgtattccta
     3001 ttttatttat ggagaaaaca atatcaattg aatcagcaag ttgtaacacc attagagttt
     3061 agtgcaatca gtccgcaagc aggattaaaa atcaattttt ctaaagaaca taacttaaat
     3121 ttaagcatac aagcaattat taataacgct catggaacta ccggaagttc aactgtaagg
     3181 tataatatgg aacttaagga tgataataaa ttgatggaag ggctttatta taaagtttca
     3241 actaaatgga ttttgattaa taccgatcat acgctaagtt caattaatcc aattattaat
     3301 tttaatattt acaaatactt cagtaaacta aaaagctggc aggtaaatat cggggcaagt
     3361 aacctgctta atgtaaatat gatcaaactt ttgaatgcag ggattactga aagaaccact
     3421 gcatcctata attatttatc gagatacgtc aacattggag ttacctttta tcctgaaaga
     3481 tggaaaaagt aatattaaaa ctcctctaac tgagctttca attcctgggc cctgtcaaat
     3541 ctgtttttgc gcgtataaat gtcaattaat aaagtgatcg taggtttatc ttttctattg
     3601 actttatgtg cctgtgataa aatgatctca gcccggttaa gattagaagt aaatgccagg
     3661 agatcctttt taggagtagc caatgcatca ttgctcaggt taagataaac taaacctaac
     3721 tgatacagcg catcgaaata attacggtct atatccaaag ccttattata agctaactcg
     3781 gcggttccca tatttgtatt tttctgatgc aaatacccat acagataata caacaactta
     3841 cttctggtct ctacctttaa tgtactttca ataacctgtc tcgcttcagt atacttctct
     3901 gtatccagca acaagttgat ataatcattg ttcaataaat cattataagg attgtaaatc
     3961 agtccctcct gcagcgtttt taaagcaagc tcattatcca gcttacgttt ataaatgtca
     4021 gccatacgct ggaataccac tgcattcata atcccgttct ccttagcacg tttgaaatac
     4081 gctaacgctt catcctcatt tttaacacct tcagcactta gcgcagcatt aacagccaga
     4141 atagtgtctt taggaaagaa atcactcact tctttcaaat atttaaacgc agcgctgaaa
     4201 tctttagcct ggtaagcaga ttttcctttc tgctgttttt taatgtttat attatagctt
     4261 gatgctttga tcagaccgga gttatcttca aacttatcaa accttttagc tgaatctatc
     4321 gcattaatag ccagatcaaa atatttatca gaattatcct gactcgggtc aacaatagca
     4381 atataagaac tcaggtaaga tttgatagcc caggtttcag gccacttctt tgtttctcta
     4441 tccttttcag cagcttctgc cgctttaatc ccttctgaca gtattgacaa ttgtgctttt
     4501 tgatcctgtt tgtttgcaat tgctgcctga agctttccta cactatttct cgcaatatag
     4561 agctgtgtct tttgggaaaa cgctgaagtg gaactcacca tcaaaatagt aactgcaaat
     4621 aaatatcgtt tcttcatcat atgcttcatt aggcttagct acaaatttat acaaaaaaaa
     4681 agagggataa aatttatccc tcttttaata tcacatttgt gattaataat tatttttttg
     4741 gtgcagcagc tggtgtacca ttttgcgcat ctaataattt tttagtagcc tcataattta
     4801 ctttgtcatc tttaaaagca taaataactt ttaagttttc taaagcagaa accattttag
     4861 gatctaattc gtaagctttt ttgtagtaag gtaatgcctg atcgataaaa cctttcattt
     4921 taagcgttac ctcatcaaat tcctttttct ttttaggatc gattttattt ctttttcctt
     4981 gtaaatctaa agcttgtttg tagtaagtat cacccatagc atattggtat gaagcgtttt
     5041 taccatcttt agcaattagt ttagccaatg attcctgagc tttagcaaca ttaccctgtt
     5101 tgatataaag gtcagtctgc ataccagaga aataagaatt ctcaggatat ttagctaaag
     5161 cagcttctaa taaagcagta ccagcaaccg tatctttcac ctggctgaat tcagtagaaa
     5221 tgatttcact gtacaaagat tcagaatctt tagatcctaa atcaattgct tttttgaagt
     5281 ttttaaccat ttcaggataa tcattgattt gcttggcagt aacacctgca tttacaaaag
     5341 ttgaagtatc ctgaggattt ttaaccgtta actcattgaa aaactgaagt gcagatttaa
     5401 aatctttttt attgtaagca aaaatagctc tgtttcttaa agcattagat aaagtttgtt
     5461 cagcttcttt gatgttatcc ttttcgctcc cttttgtatc taactcttta gcttttgcaa
     5521 ttgcttcttc agcaatttta tccttagcaa ctgcatttgc aatatttaaa gaatctacaa
     5581 atgaaattct tgacgcaaat aatgctctgt aagaccatgc ctcaggcata attttagact
     5641 tctcgtttgc aatagcatta tcagtagtct ttaaaccatc ttcaagagat tttaaggttt
     5701 catctaaagt ttttgcacca ggtaaactcg ctaatgccca ggtattttta gctttggaaa
     5761 cttcactctt ctgagcgttc gcataggtgg cagcacctat taaaagcata cttaaaacta
     5821 cttttttcat attgtaaatt ggttttaatg aatataaacc ctggagctta aaaggataaa
     5881 taatatccgt tactactaca gggtttattg ggtctgtttt taatttaatt tattcttagt
     5941 cttcttctgt ttcgtccgta tcctctgctt caccttcctc atcagaacct tcttcttccg
     6001 gctcctctgc cccttcttca gtttcagctt cttcagcacc accttcttcc ggtaatacat
     6061 ctgcaggatc taccaacaac agctctccgt taacttcttc ttcaggatca tcctcatgtt
     6121 cgattttcgc aacagatgca attgaatcat ttccttttaa gttaatcaaa cgaacacctt
     6181 gtgttgctct tccgataacc ctgagctgac tcaaaacaat tctgataacg atacccgatt
     6241 tattgataat cattaaatca tcagcatcag taaccgcttt aatagcgatc aaatcaccag
     6301 ttttatccgt aatggtaatt gtttttacac ctttaccacc acgattagta acgcggtaat
     6361 cctctacatt agtacgttta ccgtaacctt tttcagaaac taccattact gttgctgatg
     6421 gatcatcaac agcaatcatg ccaacaactt catcagcagc atgacccaga gtaacacctc
     6481 ttaccccggt agctgttctg cccataggcc ttacggtcgc ttcattgaac ctgattgcac
     6541 gtccggaacg caatgccatg atgatttcgc ttgatccgct cgttaaacta gcttccagta
     6601 actggtcacc ttcattgata ttaattgcat tgataccatt tacccttggt cttgaataag
     6661 cttccagaga agttttctta atcgttcctt ttttggtaca catgataata tagttgttct
     6721 ccagatactc ctgatctttc agattcttaa ccttaatata ggccttgatt ttctcttctt
     6781 taggaatatt gataatgttc tggatcgctc ttcctttact taaccttgaa ccttcaggga
     6841 tttcgtatac ccttaaccag aaacaacgtc ccgtttccgt aaagaacaac atatagttgt
     6901 ggttagaagc aatcagtaaa tgctcaatga aatcttcatt tcttgaatca cttccttttg
     6961 aacctttacc acctcttgcc tgtgtacggt attcagttgc aggtgtacgt ttgatataac
     7021 cttcatgaga gatagtgatc acgacttctt catcttcgat aaagtcttcc atgctcatat
     7081 cttcagcaga gtgaacgata gtagttctac gctcatcgcc gtatttatcc atcatttcag
     7141 ccagctcatc cttgataatc tgcattctaa ggccttcatc agctaagata gattgcaagt
     7201 actcaatcgt tttcatcaac tcattaaact cttctttgat cttgtctctt tccagtcctg
     7261 ttaaacggcg taaagtcata tccagaattg ctctcgcctg aatatcactt aaaccaaact
     7321 gctccattaa gcctgttctt gcttcttcag gagtatttga cgctctgatt aacttaatta
     7381 cttcatctaa gtgatctaaa gcaattaata aaccttccag aatgtgtgca cgtttctgtg
     7441 cctcgtccag ttcaaactta gtacggcgta caattacatc atgtctgtgg tccacaaagt
     7501 gtctgatcag atctttcaga tttaacatct gaggtctgcc attcaccaaa gcaatattat
     7561 ttacactgaa tgaagtttgt aaagcagttt gtttgaaaag gttattcaat acaattgaag
     7621 cattcgcatc acgtttaatt tcataaacga tacggatacc atccttgttt gattcatctt
     7681 taatattaga aataccttcc agttttttct ctccgactaa ttcagcagta cgctcaatca
     7741 tcattgcttt gttaacctgg taaggaattt cagtaacgat aatagtttcg cggtccttta
     7801 ccgtttcgat ctcagcttta gcgcgcatta caatacggcc tctaccagtt tcaaaagcgt
     7861 ctgaaacgcc attatatccg taaattattg ctccggtagg aaaatccggg ccttttacga
     7921 atttcattaa ctcaggaata gtaatttctg tattttcaat gtaagcaata gtcgcattga
     7981 ttacttctgt aatattgtga ggcggcatat ttgttgccat acctactgca atacccgaag
     8041 aaccattaat taaaaggttt ggtacttttg ccggaagcac tgttggctct tttaaagagt
     8101 catcaaagtt caactgaaaa tctacagtat ctttattgat atccgcaagc atatcttcag
     8161 cgattttctg gaaccttgct tccgtataac gcattgctgc cggagagtca ccatcaatcg
     8221 aaccatagtt accctgacct tctaccagta aataacgtaa gctccagggc tgtgccatac
     8281 gaaccatggt catatatact gaagagtcac catgcgggtg atacttaccc agtacttctc
     8341 ctacaatacg ggctgatttc ttgtaaggcc tgttattggc caaaccaaga tcaagcatcc
     8401 cgtaaagtac acgacggtgt acaggtttta acccatcgcg tacatcaggt aacgcccttg
     8461 atacaataac agacatcgaa taatcgatgt aggcagactt catctgctcg tcaatatcaa
     8521 tttttattat tttgtcgttt tcctgatttt ctaaatcttc tgccataaaa tagtgatgtt
     8581 cgttaaaaac gatttaaata aggtaatgtt ataaccttgc gaatttaaga aaatattgcc
     8641 gtttaagcgc attgtggaaa aaaattaagc ccagtctata ccttttatta acttggtcag
     8701 agttgcagcc tctgcgctgt tttctgtagt ctggtgatta tatatccact ttgccattgg
     8761 tggtaagctc attaagatag attcgatcct tccgtttgtc tccaaaccga actttgtgcc
     8821 cgaatcataa actaaattaa attctgcata acggcttctt cttacatatt gccattcctg
     8881 ctgcgctgct gtaaattcag tatttctgtt ccgttcaatc agttcagtat aagccggaat
     8941 gaacgaatta ccaaccccca gggagaaatt aaacaattga tcccaatcca gcccggtatt
     9001 ttcaggtttc agcctgtcat aaaaaatccc acctacacca cgcatctcat tgcggtgttt
     9061 gatgaagaaa taatcatctg cctgtttttt gaatttcgga taaaacgaag catcaaactc
     9121 atcgcaggtt tgtttcagca gctgatgaaa aaagcgcaca tcctcatcaa ttacataatg
     9181 tggcgttaaa tcaatgccgc caccaaacca tcttgtttgc tcatccattt cgaaataacg
     9241 gatattcata tgtataatag gtacaaatgg atttgaagga tgaatcacaa tggaaactcc
     9301 ggtagcgaaa aattcatcat tttctacctt gaaagctttt ttgaccgctt ctggcaattt
     9361 accatataca gcagagaaat taaccccacc tttttcaatt acatttccat tctgaaaaat
     9421 acgcgtgcgg ccaccgcctc caccctctct ggtccagatt tcttcttcga actgccctcc
     9481 gccatcggct gaagccaaag cctggcaaat ttcatcctgg atcttttggt acgcttctac
     9541 aactttatct tttaacatcg ttccgtgaat atataaggtg gtaaagttat attttaatat
     9601 atactagtac aaacgtacta tgtaatacaa ttgtattata caaaaaaagg ctttgctcag
     9661 aaaaaaacac ccccggtcag gccgaatgga taatctcaag aatttttcct ggcaacatac
     9721 ctttctctaa ctaactatat atactgttat attcaataaa taattttata gatattataa
     9781 atattaattt atatttttaa gaaactaaaa ccaaaatctg atgaaagaag aaaaaaagca
     9841 atttaaattc tccttaaaca aaaaggtaat ttcaagcatg gccaacagtc agccaacaaa
     9901 tttaggtcaa ggtgcaaatc aacttgttga tagctcaact tgccaggtac agtcctgtca
     9961 tcaatgcatt actgtaccta tacctacaat ctcattttaa ttaaggagat attacagcct
    10021 gattttttga ataaagaacc aggctgtaat atttagacaa taattgataa gtgatcaatt
    10081 catttatctt ctggtgctct ttaaacagcc tgttcacctg catatgggca aggctgaaaa
    10141 tatatgattc caaatcaggt cccgttgctt tcgccgtttt atacaattcc gctaattcaa
    10201 ccttccaatt cgacaacaac ttatttattt cggatccatt ggctggttgc aaaaccatca
    10261 gttctgcaat ccccgattta tttgctttaa attggacatc tatttttttc caaaaatctg
    10321 tatctatctt atatccgctt tccatggatt ttttaaactg gcccactaac cgaagttttt
    10381 ctttagtctc aaaattgaaa gccgacagga tgtgatctac tgacaccata gataaaaata
    10441 gtacctgttg ctcactgcca atcgatctat tcaaataagc taacagtttt agcgtatacc
    10501 ggctgctgag aaaaaatgca gtctctgata tatccattcc ataagtatga taacgctcaa
    10561 tctccggttt gtaagtgtca aactgtattt tccatgcttt cttcctgcta atgagtattt
    10621 ccagacacct gttgagctgc gctgttatcc tgggtatatc atttttgttc tttacagcta
    10681 acctgactct tatatggtac cctggatcag tataacggat aaaaaaccac ttatctatca
    10741 gtttatcttt taataatcta ttggttagct tgtctatggt ccctaccagg atttcatcag
    10801 aaatagttcc gccacaatag attttaaaat agatccattc acttaaagga taaaattccc
    10861 tgactttcgg gatattggca atagtttttt ctccggtata tattgagtta cctttgcctt
    10921 tcaaaaaggc cgtaaattga ttcgtatttc cattctcacc agaaacaaca gtatcccgca
    10981 caggaagaaa aagttcctta attagtacag cactcttttt ggataacaac tgaagtataa
    11041 cttttctgct tgactcttca ttaaggtctg caaaaagttc attatctcca tctgacacta
    11101 taaactttcg aggtacaccc cattttttca tgaacggggt atgttggaat tctttaatat
    11161 cctgaatgaa caaagcaagg tcctggtctt tgaaattcca gcttgcgagg cttaaaacgc
    11221 tggatctgca gacaaccctt ggaaaaaaga caagtccctt taaggctgca ggccactgaa
    11281 acaaaagcga atttttatcc tgctgcaact gaagatcaca taaaaactta taaacaggaa
    11341 ggtttctgct atgatgaaaa ttatgtgcac ttgaaagaat gggaataatc tcccgtttca
    11401 accgctttga atgcagaacc agtacctctc ccctcagaga tattaacaaa tcatttaccg
    11461 gaatctggtc ttctgccgga atagccgagt tgtaaacaat tgaaatctga tatcttgtta
    11521 accggggtct gattagaaca ttacccatta tcgggtctgg ataatggctg atttctgcgt
    11581 atatgggttg atcctgttca tcaaacggtg gtgaaaacgc catggccacc tctttaatat
    11641 tatcgtctat tgtagcaaac cttgtaatcg tattgattgc tccatgtaaa ccagcacttt
    11701 ccagaaatat acgttcatca gctacacgga ataatacaaa tagattctcc tggataaatc
    11761 catcaccctc tacattgacc agcttcaaca gctcagattt ttccagcctg atttcttctt
    11821 cccgattgcg ttgactttct ataaccttgt ttaacaggta actactcatt gcatcccagg
    11881 cctgctctgt tttatcctta gctaatggtt taatgctctt catcagccca ttcataattt
    11941 ctcctgaaat ggaaatatcc gagtatccaa ttccattttc ctggtccaga atttcgagca
    12001 atggtttctg ctgtgtttca taacgatcag caaattttgc aataaactcc tgaagcatgg
    12061 gatttttatt tggcctgtga tttaaaatct tcaaaacttc cagaccttct atcaggggat
    12121 gctgaaaact tttatcaagt cctccggtat atgcaggaaa catagaaaca ttaacgagtt
    12181 tatggagagg gaccttaatc ccgaatacac tctctatatg ttgttttagt ttcagatagt
    12241 ttgaacggtt ctgtactctt tgtatatcaa tttcactaag cagacctgta atagctttga
    12301 ggtcattgac atagctattg atttcctcac tatggtgtaa agttcccgtc tgctcaagag
    12361 caacaatgat ttgctccagc gggtcagtac ctatgagctg aggaatgagt gcatatacta
    12421 atattccagc ggatatcatt tcctgcaaaa agtcctttat tgcattttcc tcaccggggt
    12481 aagatgctgt taaataatcc actatttgcg gaaatgtctt tccgtctctg caaaagttta
    12541 gtatcgtctt actaattgaa gaatagtcaa aagaactcaa ctggaactga gataagctat
    12601 gaggttcaat ataacgataa gaattattga ctttatatat cgaagaattg ggataaagtt
    12661 tcactacact tttcatcatc tcattcccca ttatacttct gcagatagca tccaggcaag
    12721 aaatatcaag ttttgtcacc cgtttaaacc catgtaatcc gatggtcttt ttttctccgg
    12781 cagaccagtc aatcacgttc atccctgcat ataaaccaaa gggagtagtt ctgaaagaag
    12841 cacggagaaa atattttgaa atggtcagct ttatttgctc attctctggg tctgccaggt
    12901 acaactcaaa tagctccggt gcacttataa aaagcgcttc caggaaaata ttattttcaa
    12961 gataactact gttcaataaa gctgcctgga tatcagtata aggtaaaaga gaagtacgca
    13021 gtaccagctt gttataaaaa ttatatttgg gcatagcttt ataaatataa aaaacaggta
    13081 aaaggcagat acttctcgtc catatgagcg agaaaagcca gacctattcc actcaggccc
    13141 gtcataaaac ccagattgat ctccgtactg tccttgtaaa aaaatgcctg ataacccgca
    13201 aatccattca ctgattttgc atgttttagc gttttatcaa taaagtcatg ataagcagtt
    13261 tgcaaaacag gtgaatcaca aagtaacagt gcttttttaa gtactatggc gataccagca
    13321 ctaccatagg ataaactagc atcatctatg taattttgag gatcagttct tttaactgta
    13381 ttttccaata tttcaattcc tgttttttca agcagttcat ttttcaaatg aagccctgca
    13441 ttcagtagtg tatatccaat agaaaggtca ccataacacc attctacggg agtttttacg
    13501 acttcctcac caatttttgt aggaaagtaa aagttgtatt cttcaaaatt aagtttatgc
    13561 ttcagtaaaa aatcaatgct attcacgatt aactttttaa tggtatcatc gaacttaaat
    13621 ttgagatctg cttttaatag aaactgtata atagcacagc ttccatgtgt aattccagta
    13681 taaataccac cattactaaa ttttggtgat ttccaaaata aatgaccgtc tttatcctga
    13741 attgaaataa aggatattgc cttaactatc tttaagatcg catctcgtga aacctgcgta
    13801 tccctattga gcagataata tccctgtgcc agaaaaccgg taaaagggtc aaaatcctgg
    13861 gcttcaatat ttttgtcaac aaaatcatca gctattacat ccagatcatt cagtagctca
    13921 tctgagctga tgtccaatag atcctgatct ttcatataac ttaaaaagat acccaaatca
    13981 gccatttcct tccctaatgt atcagaaaca tatccgctat tgatgtcttc cagtatctct
    14041 gaaacaattt cttcagttaa gtcattgtat tgcccctctc cagaaaagtc gctataagaa
    14101 cttaggaaca aggctgctcc cagtctcccg tctttcacag aaatccgagg tagcgagctg
    14161 tagttttcag ataaaatctt agcaatttca ttaatcttat tcttcataac ttaatttgca
    14221 tgaatagtat tatgatggta agatataaat ttttaaaaac ataaactata atgttgacta
    14281 agataaaatc atgctaatta aaaattaata aaaaaggctt tgccgatcaa ccagcaaagc
    14341 ccctaaaaaa atcaactacc tattattaaa ctattttttc ggcattaata ccgcatcgat
    14401 tacatgcgtt accccattgc ttgaaactgc atctgtgatg gtaatttttg catcattcac
    14461 ataccactga ccatcttttt tagagaattt aattttctgt ccctgaacag tagtcagttc
    14521 caggccatct tttaaatcag cagctttata atttcctgcg acaacatgat aagttaaaac
    14581 accagcaaga tcttttttca tttctggttt aagcaattta gctacagtac cagcaggcaa
    14641 tttatcaaaa gcctcgtttg taggtgcaaa tactgtaaaa gggccttttc cacttaaagt
    14701 ttctgctaaa ccagcagctt taacagcagc aaccaatgta gtatgatctt tagattcaac
    14761 cgcattttct acaatatttt ttgaaggaac cattaaagca ccacctacca taacaccttc
    14821 ctgagtactc atttttgaag tatcagccat gcttgacatt ttactgctgg tatctgtcat
    14881 tgtagtcgtt gaagtatcag tagtactacc aggttttgat gagttacaag ctgaagccaa
    14941 agaaagaaat gcaagagcca ttgcaaccgt aaaaatttgc tttttcataa agtttaattt
    15001 tgttttgtcc gttttgtaga ctgatatacg ggatcaatag cctcccggtt ttttataagc
    15061 agattattct ctgagaactg taaaatttag catattaatt tctacaggtt ctacaagatc
    15121 ccaataatct ttctgatatt taaagctcat gatagtatca gaaagaacac taaaatgggg
    15181 actgtgcttt tatcccccgc ttctcttcca gcgtatttgg gttaagaaat tccatccagg
    15241 gttcagggga gctgatatta aaatctataa aagccttttc aataaaaact ataacggttc
    15301 catatttggc ggaactattt atgccgctac agacccattt tatgcattat tatttgatca
    15361 gcttttacag cgccagggat ttaaagtcag agtatggctc aaaagtgcaa gcatacaata
    15421 cctgaaacct ggtagatcag cccttttttt tactattatt attactgatg agatgctgaa
    15481 tgatgctatt gaagcgttaa ataccagtgg caaatttgtt aaagcttacc ccatggaaat
    15541 taaaaacagc gctggtgaag tttgtgccac agtgatgaac gaggtatatg tcagaaacct
    15601 gcacagtggc gaaaatggcc cggtagctta ttaaatagaa atgtccgtta aaacctctaa
    15661 aaatgaatat caggaaactt attttgcaag gagaaggaac tacactggat tttaaaaaga
    15721 caattaataa ctatgaaaag attgcaaaaa gcctggtagc ctttgccaat aacaaaggag
    15781 gacaattatt gatcggtgta gccgatgacg gcacgatcaa aggcgttaaa tctgaagaag
    15841 aagagaaata catgattacc agatctgcgc atcaattctg caagccagcg attgaaccgg
    15901 aatttgaaga aatatacatt gatagtaaac tcgtactggt cgcgaaaatt ccgcaaagtg
    15961 acaccaaacc gcactatgca ctggacgaaa acaaaaaatg gtgggtttat ttccgggtca
    16021 atgacaagag tattctggcc agtaagatca tcgttgatgt actgaaaaaa gaaaataccc
    16081 acagcggaca attgatcacc tacaccgaac aggaacaaaa gttattaaag tatcttgacc
    16141 aggaagggcg tattacctta aaacaattta gtaaacttac taaaatctct aatcagaaag
    16201 cgcagaggat attggtcagc ttcattcttg ctgacctgat tcagccccat tcttccgaaa
    16261 aagaggaata ttttaccatg acaacgccga aatagccgta cctttgacgg ttcaattcaa
    16321 tcgttatgtt cagttccttt tacgcaaaat acaagcctta ttattcagat aacctcagac
    16381 tggccatgcc tattgtggta tcccagctgg gccacaccgt tgtgcacctt gccgacagtg
    16441 tgattgtagg acattttgca ggaacaattc aattggctgc ggtttctctg gtgaatagtt
    16501 tattcatgct gatcctggtt ttaggaatgg gtatctccta tggactaact ccgcttattg
    16561 cgcaggagaa cggacgtaaa aactataaag aatgcggaag gttattatca aatagcctgt
    16621 tgattaatat catgataggg attttcctgt atctcttggt acactttgga accttattgg
    16681 ttattgataa tctcggacaa tctccagaag ttgttgccta tgcaaaacct taccttggat
    16741 acctgagttt ttctatcatt ccactaatga tttttcaaac tttcaagcaa tttgccgaag
    16801 gattgggttt taccaaacaa gcgatgttta tttctatctg gggaaatatt atcaatgtta
    16861 tcctgggaat aatcctggtt aaagggatgt ttggcatcgc tcctatgggc gttaaaggtg
    16921 ttggtatcag tacgctggta gacaggatat taatggctac ggtgatgtgc atttacgttt
    16981 ttaactccaa aaacttcaaa atatatctgc aaaactttaa actcaccctg atcgacaaaa
    17041 taagaagtct caaaatctta aaaataggtg ctccggttgc tttacaatat tcttttgaga
    17101 tcagtgcatt cagtggagct gcaatcctga ttggtaccat tggtgctgtg gaacaagcag
    17161 cacaccaggt agctattaac ctggcttctg taacttatat gctggcaagt ggaattgcat
    17221 cagcagcgac cattaaaact ggtaataacc tgggtaaaaa caacttcctt gatttgagaa
    17281 ggtcggccat agcaagttac catactgtgg ctgtttttat gagtattacc gctgttgcat
    17341 ttgtttgtgc gaatcatctg ttaccttata tctatacaga ggacactgca gtaattaata
    17401 ttgcagccca attgttgatt attgctggtt tcttccagtt atttgatggt acacaagtcg
    17461 taggattagg tgttttaaga ggtttgggtg atgtaaatat ccctacagtg atcacttttg
    17521 tagcttactg ggtgattggt atcccactag gttatctttt aggtatcaca ttagagatgg
    17581 gggtcaacgg aatctggtac ggtcttactt ttggattact taccgcctct gtgatgctgt
    17641 ttttcagatt tcagaaaagg acaagaatgc tggttgctgt tcctgcataa aaaatacaaa
    17701 agcccgtttt aaaacatttt ggcctttact tttgtacagt aagggaaagt ctttttaaga
    17761 ttcttatttt cttgcgtatt tcacacttat ggctaatcaa aaagcatcca tttacagcgc
    17821 gctggcagcg aacctgctta ttgccattac caaatttata gcaggtgcat tcagcaacag
    17881 tgcttctatg atttccgaag ggatacattc tgtagtcgat actgttaacc agcttttact
    17941 gcttttcgga ttacaaagaa gcaagaaacc tgcggatgca ctccgtccct tcggttatgg
    18001 aaaagagctt tacttctatt cctttatcgt ttccatcctg atttttggtc tgggtggagg
    18061 aatttctatt taccagggga tcattcatat ctcaaaccca gagcctcttg gagatccaac
    18121 ctggaattat gtggtacttg cgttatctgt tgtctttgaa ggcacttccc tgattatagc
    18181 tgctaaagct ttcaataaag tcagaggtca tgaaacctgg tggaacgcga ttgtaaaaag
    18241 taaggatcct tccagcttct tagtgctttt tgaagatggt gcagctgttt taggattatc
    18301 aattgtaatg atctgtatgg tcatcggtca ccagtttcat attccacaac tggacggtgt
    18361 agcctcctta ttagtcgggc tgttgttagt cggggtttct ttgatcctgg ccagagaaag
    18421 ccggagctta ttgatgggcg aaggaatctc tgcaatatca agacaaaaaa tcgtggagaa
    18481 aactgaagca gttccgggag ttgtcaaagt tttaaccgtt gtatccactt accagtcacc
    18541 agaggaagtg ttgttaatgc tgatcgcaac tttcaaagaa gacctgaata cccaccaaat
    18601 caatgaagct attgacgcta ttcaggctgg gatcagaaga gaattcccat taatccgtta
    18661 cattattgta cagccagaag agtttacaaa gcagtttaag ttttaaaaac tggttgctta
    18721 ttcctgaaac atgcctataa actgatagtg ttctgtaggt attatccatg ttatcagtta
    18781 gtgataacat ttaatttata gtcgattatt gttttaatga agcattatta tgcattatta
    18841 aaacaataat tgatttaaac tggctactta ggatttaaaa aaagaaaaca atcctttttt
    18901 ccactccttc ctccttttca gtgcttcttc gttagccgga taagcttcca ggatattctt
    18961 tatattttcc aaagcttcac ctttagaacc cgttttatat aaagcatctg catattgtaa
    19021 ttttaccttt aaaagttcgt catcccaggc ccattcattc ctgatataac ataatatgcc
    19081 ctgataagca ctctccttac aattatccca cttattcaag atgaaataac aatcagcaag
    19141 atgcagataa gctctgctca attcgtactc attatctggg taaactattt ttaaaggtgc
    19201 aattaaagct ttcagatctt caattgcttt ttcgtaattg ccaaggttca tataagataa
    19261 tccgcgcata taatgaattt tgcaacgtga agtatcttgt attgcctctt tcttgacaga
    19321 ttgatagtta tctgcacaag caatacactg gctataatct ttgatgatat aatattcctg
    19381 catcagcata aaccaggcag aattatcatc ggggttttta accagctcat tttgccacgc
    19441 tttaatcgca tcttcagggc ttcctttact cagcaaatca tggcggacat tttgaatgat
    19501 aatatattgt tcgcttagct caaacaattg agcttctgtg agctctttct tattaatttc
    19561 caaaaaagag tcatattcct cggttatgga gtccaggatc tcataagttt gctcattacg
    19621 gcccagttta taagtcatat ccagaatctc agctttgatt ctcagataag ctgaaaaaga
    19681 caggtaatca ctactataag ttgcggccac ctcgtatatc tctatcgcct gctcatattt
    19741 ttccaacccc ttaagcgctg ttccccagct attcaactgc tcccaaaaag gagaaagaga
    19801 ataaccaata gcgtgaactt cagcagcttt ttcgaaagcg ccgatttcag aaagagctat
    19861 tccgtaatta ttacagcaca ttgcaaaagt atgaacctcg tttgctaaac tttcgccagt
    19921 gttattatag aaatattcat aaaagccttg ataagaaatc tcataaaact tgactttgat
    19981 ttcctgtaat tcctctgaaa gtccttcagt ccagatattt gggatagact cataataaaa
    20041 atcgcagcct gcagcataat aagcttcagg agaatctgct ggcaaagatt cgatgtctgg
    20101 tagttgcccc ataatgcggc aattggcatc aatataacga cgaaggcctc gcgccaggcc
    20161 tccaatctct aaactctttt tcaaataagg aagcgcttct tcatacttct tttcatcaaa
    20221 taaaaatgta cctgcaaaat gatatggaat atcccaatca ggataaactt tcatataact
    20281 aagagaaaga cttaatattt caatcgggtc tgcctttaaa tgttcagaaa atcttcttaa
    20341 agccaatatt aaactatata ccaatagctt attcagtttg ctttttgcgc tcaagtcgtt
    20401 aatcctgtgg taaaggtcaa tcagctcttg gttaggctgc tcatcgctat aagtaaaggc
    20461 cataaaagct gcttctccag ccagttctaa tcgctggtaa tctaaggcaa gtaaagcaac
    20521 tgcattatgt gtcagataat tttgatgagg atacgcctta ccttctctga aggtctgaaa
    20581 cacttgtagc gcatcttctt tatgccacag ataaatattc gtcttttcca gataaagcag
    20641 gcctaattcc tgatcaagga tacttctatt gttaggatac agtgctttat aatgtgcaat
    20701 cattaaatct atatcttcca atacaagctc catatttccc aggataaaat taacctgacg
    20761 gcgataaccg atcgctttta acctggtatc ttcgttctct gaaaaaacaa ggatatcaca
    20821 ataaacctgt gcttctggta agttatcctg tgttacaaag atattgatat aagcagcata
    20881 taacattgct tcctcatgcg taggctgaag ttttaaaacg tattcaaaac tatgatatgc
    20941 agttatatat aaggatatat cgtttgtatc tggatcaaaa gtctgactag ctgattgata
    21001 ttcgcatctg gctttgagca gcagcccttc aatgctatca ggattcacca ggagaaaagg
    21061 attcaaagat tcaaggcatt ttgaaaattc accttgatta taaagggatt gtaagtcttg
    21121 tatggttgtc atatgtaatt tatcctatgc actgcgctat gttgaatggc taacataata
    21181 gctcaattta gcggcaaata taagattaca cgaaataaag agacttgttt agcttaattt
    21241 tttttaaaaa cacaaaagca cgggcaccac tttacgctga aaaaatatat cagacaagac
    21301 tttagcgtat ccggataaga ccaaaaacta aaaattgatt ttcttttcca tttcaatcag
    21361 gatgatttct tttaatggtt tgccgtattt atgatattct acaggaaatg ggaattttct
    21421 gccagtagtg acatatcccc tcctttgata ccacgcaata agttctgttc tgtcttcaat
    21481 cacggttata ttgattttat tgcaattgag ttgtctggca tgttcttcag caccatgtaa
    21541 aagcaatctt cctatacccc catcctgaaa ttcgggatta actgcaagca tgcctaaata
    21601 gagatgctct tctttttgct ccaggtaaac gcaaccaatt agctgattgg cagggttggt
    21661 aaactttaaa acagaaatgg atggatttgt aaggtagtcc gttagtattt cttcatctat
    21721 acggatctcc cctgctaata aaagaatttc ggatgtccat cctttagtag aggtttcacc
    21781 acgataagta gtattgacta agtttaataa cgctgataaa tcagaaattg aagcttttga
    21841 aattgacatc atgtaaaaaa acgaagatag cagaaatatg ataagttttt attgaacaaa
    21901 taaatgtgtc aatcttctta atggggttgt taatttatag ttatattgat tatatcattt
    21961 tattaaccta aactaattta ccaatgaaaa aattaatcat cttattgagc atgatcatgc
    22021 tatttctaca gtttactccc ttttcgcaag ctgtagctaa agaaaaaccc gctgttaaaa
    22081 aagacttccg gattctgaaa gccattcttt gtaattatcg tcttactccg ggtggcccgg
    22141 gaatcgctgc tccatttgct accttaatca atgtaactac tggagaaacg acgactactg
    22201 atgccacggg acatggaggt ttaaggctaa aactcatgga taccattgtt gcaaaagtca
    22261 atattcctgg ccaggggtgg ttttctacaa ccagattata ccggcttgaa caattaggat
    22321 tgactttgct ccctgatcca aatatcactg attaaaaata tattatttaa taaagccgtc
    22381 ttcaggcggc tttattgact ttaataataa aatacaataa atcggcttga aattaaaacc
    22441 atttgtttgg ttatgggtta tagcgccaat ctagttggct ccatatgaaa tttaacaaca
    22501 ctacttacca gatatgagtt tatcagaacg aatcatcgcc tctaataagg gcatgcttgc
    22561 tgagatggta cagctcaaat accaggcaat gactgaaagt gcttttcgtt ttttcagagg
    22621 aacctgcgag attttttatc aggacctgtc actttggaaa gcaatgccga aatctccttt
    22681 aagctggata tgtggtgact tgcatgtaga aaactttggg agctataagg ctgacgatgg
    22741 tcaggtatat tttgacctga atgactttga tgaagcgttg ctggctcctg tagcatttga
    22801 attggtcaga atgctgacga gtattttcct ttgttttgat ttcttagaac tggaagacct
    22861 gaaagcgatg aatatggcaa atgtctttct gaaaaattac agtgcagttt tagcccgggg
    22921 gaaagcgctt gctattgaac ccagaattgc aaaaggtatc atttgtacat ttttgatggc
    22981 cgtctctaaa cggaagcaaa gccgcttact ggacaaacgt actgaagtca gaaaacggaa
    23041 actggtactt tccctggaag atgaaagaca ttttgagctg gataaagacc tgagaaaaga
    23101 tttagtggaa catttgacag actggatcaa taaccatagc agaagtccct ataattataa
    23161 agtacgtgat gtcgtttttc gtctggccgg caccggtagt gtgggtacaa aacgctacat
    23221 gttcttactg gaaaacttgc taaagaaagg gaaatatttg attgtggata tgaagcaatc
    23281 gcagccgagt gcacttaccc cctatgttaa agtttcacag cctcaatggg aaactgaagc
    23341 tgaacgtgta gtttttgcac aggaactctc ccagcatatg ccttgctcac tgctgagcca
    23401 tactgttttt aagggggacg cttttgttgt taaagaaatg caacctgctg aagataagat
    23461 caagttcaga ttaattcagg atcaatacag agatatcttt caggttattg atgatatggc
    23521 agcgttgaca gcttcggcac atatcagaag ttcaggcaga aagggttcag ccattgctga
    23581 tgaacttatt gaatttggta gaagtacagc atggcaggaa aaactcatcg actatgcgtt
    23641 taaatatgca caaaaggtga agaaggattt caaggtattt aaaaccggag ttgattcggg
    23701 tatctatgcc aatagttaat tattattctg caaataactt atatttgcaa actttcttaa
    23761 cgtctttatc agtatcaaat gattgaagat accttcggaa tgaatatcat tccggataat
    23821 gattccgaaa gacttcaggc acttaaacga tacaggatta tggatagccc ttctgaggct
    23881 tctttcgata atattgcccg tttatgcaca cagatattta atgttcctaa ttcagggcca
    23941 ggataaggat aaactgtttg atcgttttta tagggttctg aacgatgata ttgtttcagg
    24001 ctttggtatc ggcctttatt tatgtgctga aattatagac cggcaccagg gaaaaatcgg
    24061 ggtggaaagc gaattcggag aaggcagtac tttttggttt agcttaccgg tcgctgtagt
    24121 ttcagtttag tataaaatcc gtttttacta atctttcttt tgaacagctg gaaattataa
    24181 tcgctgttac acaaagaatt gttgcag
//
