GCF_001587285.1 - 14 region(s)

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Location: 1 - 9,329 nt. (total: 9,329 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Ligases: ligase

B4090_RS05170: condensation domain-containing protein

smcogs: SMCOG1127: condensation domain-containing protein

B4090_RS05175: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002135.2	0.71	NRPS	bovienimide A	Xenorhabdus bovienii SS-2004
BGC0000342.4	0.68	NRPS	enniatin	Fusarium equiseti
BGC0001166.5	0.68	NRPS	HC-toxin	Alternaria jesenskae
BGC0001135.5	0.68	NRPS	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001833.4	0.68	NRPS	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825.4	0.68	NRPS	xenematide	Xenorhabdus nematophila AN6/1
BGC0001132.4	0.67	NRPS	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0002286.3	0.66	NRPS	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001128.4	0.66	NRPS	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001240.4	0.66	NRPS	serinocyclin A, serinocyclin B	Metarhizium robertsii

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002135.2	0.71	NRPS	bovienimide A	Xenorhabdus bovienii SS-2004
BGC0000342.4	0.68	NRPS	enniatin	Fusarium equiseti
BGC0001166.5	0.68	NRPS	HC-toxin	Alternaria jesenskae
BGC0001135.5	0.68	NRPS	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001833.4	0.68	NRPS	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825.4	0.68	NRPS	xenematide	Xenorhabdus nematophila AN6/1
BGC0001132.4	0.67	NRPS	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0002286.3	0.66	NRPS	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001128.4	0.66	NRPS	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001240.4	0.66	NRPS	serinocyclin A, serinocyclin B	Metarhizium robertsii

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Module view

Legend

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 9329:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Val - Asp)

Direct lookup in NORINE database: strict or relaxed

NRPS/PKS substrate predictions

B4090_RS05175: Val - Asp

Search NORINE for peptide: strict or relaxed

AMP-binding (470..862): Val

nrpys: Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: val (Val)

Stachelhaus prediction details:

Stachelhaus sequence:: LNAGFDASTFEGWLIIGGDWNGYGPTENTTFSTC
Nearest Stachelhaus code(s):: Val DAFWIGGTFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1502..1905): Asp

nrpys: Asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: asp,asn (Asp, Asn)
Single AA prediction:: asp (Asp)

Stachelhaus prediction details:

Stachelhaus sequence:: YWFSFDLGYTSPKLVLGGEINHYGPTETTIGAIA
Nearest Stachelhaus code(s):: Asp DLTKVGHIGK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

NZ_LQYL01000002.1 - Region 1 - azole-containing-RiPP

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Location: 1 - 12,328 nt. (total: 12,328 nt) Show pHMM detection rules used

Region on contig edge.

azole-containing-RiPP: ((YcaO or TIGR03604) and (((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or thiostrepton or TIGR03602)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

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Gene overview

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MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Azole RiPPs

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

No tailoring functions detected.

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002115.3	0.45	ribosomal	streptamidine	Streptomyces albidoflavus J1074
BGC0002151.2	0.42	ribosomal	alboverticillin	Streptomyces griseocarneus
BGC0002150.2	0.42	ribosomal	triculamin	Streptomyces triculaminicus
BGC0000558.5	0.42	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0002306.2	0.42	ribosomal	freyrasin	Paenibacillus polymyxa ATCC 842
BGC0000551.5	0.42	ribosomal	SapB	Streptomyces coelicolor A3(2)
BGC0000513.3	0.42	ribosomal	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0001555.4	0.41	ribosomal	colicin V	Escherichia coli chi7122
BGC0000607.5	0.41	ribosomal	micrococcin P1	Macrococcus caseolyticus
BGC0001639.3	0.41	ribosomal	klebsidin	Klebsiella pneumoniae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002115.3	0.45	ribosomal	streptamidine	Streptomyces albidoflavus J1074
BGC0002151.2	0.42	ribosomal	alboverticillin	Streptomyces griseocarneus
BGC0002150.2	0.42	ribosomal	triculamin	Streptomyces triculaminicus
BGC0000558.5	0.42	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0002306.2	0.42	ribosomal	freyrasin	Paenibacillus polymyxa ATCC 842
BGC0000551.5	0.42	ribosomal	SapB	Streptomyces coelicolor A3(2)
BGC0000513.3	0.42	ribosomal	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0001555.4	0.41	ribosomal	colicin V	Escherichia coli chi7122
BGC0000607.5	0.41	ribosomal	micrococcin P1	Macrococcus caseolyticus
BGC0001639.3	0.41	ribosomal	klebsidin	Klebsiella pneumoniae

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 24.21 out of 26.06

Confidence: strong

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.02 out of 26.06

Confidence: medium

HipB

Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 25.99 out of 33.73

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.30 out of 28.19

Confidence: medium

Additional weak hits (8):

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 20.97 out of 26.06

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 20.23 out of 26.06

Confidence: weak

ArcA

Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 18.69 out of 21.55

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 21.56 out of 29.38

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 20.86 out of 26.06

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.60 out of 26.06

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 20.79 out of 26.06

Confidence: weak

CopR

Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 21.62 out of 30.97

Confidence: weak

(Thi)azol(in)e containing peptide predictions

No core peptides found.

RREFinder

TFBS Finder

Azole RiPPs

RRE predictions

: RRE type: Heterocycloanthracin_C_RRE; Location: 0 - 100; Score: 168.3; RRE type: Thiopeptide_F_RRE; Location: 7 - 89; Score: 49.0

TFBS definitions

Regulator	Description
HipB	Bacterial antitoxin HipB
MogR	Repressor of flagellar motility genes
ZuR variant 1	Zinc-responsive repressor

Core peptide predictions

No core peptides found.

NZ_LQYL01000002.1 - Region 2 - NI-siderophore

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Location: 143,615 - 177,081 nt. (total: 33,467 nt) Show pHMM detection rules used

NI-siderophore: IucA_IucC

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase oxidoreductase oxygenase

B4090_RS01305: oxidoreductase

smcogs: SMCOG1079: oxidoreductase

B4090_RS01355: lysine/ornithine N-monooxygenase

smcogs: SMCOG1080: lysine/ornithine N-monooxygenase

B4090_RS01370: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Transferases: acetyltransferase aminotransferase

B4090_RS01295: GCN5-related N-acetyltransferase

smcogs: SMCOG1111: GCN5-related N-acetyltransferase

B4090_RS01330: aminotransferase

smcogs: SMCOG1019: aminotransferase

B4090_RS01335: aminotransferase class-III

smcogs: SMCOG1013: aminotransferase class-III

Lyases: decarboxylase

B4090_RS01340: Decarboxylase, pyridoxal-dependent

smcogs: SMCOG1180: Decarboxylase, pyridoxal-dependent

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002633.2	0.65	other (other)	schizokinen	Leptolyngbya sp. PCC 7376
BGC0001499.5	0.63	other (other)	aerobactin	Pantoea ananatis
BGC0002683.2	0.63	NRPS	schizokinen	Nostoc sp. PCC 7120 = FACHB-418
BGC0001478.5	0.61	other (other)	desferrioxamine E	Streptomyces sp. ID38640
BGC0000941.3	0.60	other (other)	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001572.3	0.59	other (other)	desferrioxamine E	Pantoea agglomerans
BGC0002469.2	0.59	other (other)	woodybactin A, woodybactin B, woodybactin C, woodybactin D	Shewanella woodyi ATCC 51908
BGC0002470.2	0.57	other (other)	synechobactin C9, synechobactin C11, synechobactin 13, synechobactin 14, synechobactin 16, synechobactin A, synechobactin B, synechobactin C	Synechococcus sp. PCC 7002
BGC0002305.2	0.57	other (other)	legonoxamine A, desferrioxamine B, legonoxamine B	Streptomyces sp.
BGC0002692.2	0.57	other (other)	speibonoxamine, desoxy-desferrioxamine D1, desferrioxamine D1, desferrioxamine B, didesoxy-desferrioxamine D1, desoxy-desferrioxamine B, didesoxy-desferrioxamine B	Kribbella speibonae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002633.2	0.65	other (other)	schizokinen	Leptolyngbya sp. PCC 7376
BGC0001499.5	0.63	other (other)	aerobactin	Pantoea ananatis
BGC0002683.2	0.63	NRPS	schizokinen	Nostoc sp. PCC 7120 = FACHB-418
BGC0001478.5	0.61	other (other)	desferrioxamine E	Streptomyces sp. ID38640
BGC0000941.3	0.60	other (other)	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001572.3	0.59	other (other)	desferrioxamine E	Pantoea agglomerans
BGC0002469.2	0.59	other (other)	woodybactin A, woodybactin B, woodybactin C, woodybactin D	Shewanella woodyi ATCC 51908
BGC0002470.2	0.57	other (other)	synechobactin C9, synechobactin C11, synechobactin 13, synechobactin 14, synechobactin 16, synechobactin A, synechobactin B, synechobactin C	Synechococcus sp. PCC 7002
BGC0002305.2	0.57	other (other)	legonoxamine A, desferrioxamine B, legonoxamine B	Streptomyces sp.
BGC0002692.2	0.57	other (other)	speibonoxamine, desoxy-desferrioxamine D1, desferrioxamine D1, desferrioxamine B, didesoxy-desferrioxamine D1, desoxy-desferrioxamine B, didesoxy-desferrioxamine B	Kribbella speibonae

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 23.61 out of 25.88

Confidence: strong

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.51 out of 23.79

Confidence: medium

CelR

Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 23.29 out of 30.11

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 20.57 out of 27.78

Confidence: medium

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 26.42 out of 29.38

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 21.26 out of 28.19

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.18 out of 28.19

Confidence: medium

Additional weak hits (5):

CelR

Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 21.23 out of 30.11

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 22.17 out of 29.38

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 21.93 out of 29.38

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 23.46 out of 29.38

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 20.17 out of 26.06

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
CelR	Cellobiose uptake repressor
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
FuR variant 1	Ferric Uptake Regulator
IolR	Regulator of the inositol catabolism
PsrA	Oleic acid responsive regulator
ZuR variant 1	Zinc-responsive repressor

NZ_LQYL01000003.1 - Region 1 - CDPS

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Location: 76,059 - 96,808 nt. (total: 20,750 nt) Show pHMM detection rules used

CDPS: CDPS

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

NRPS/PKS domains

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase oxidoreductase oxygenase

B4090_RS03205: oxidoreductase

smcogs: SMCOG1079: oxidoreductase

B4090_RS03225: cytochrome P450

smcogs: SMCOG1007: cytochrome P450

B4090_RS03245: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Transferases: kinase

B4090_RS03260: glycerol kinase

smcogs: SMCOG1210: glycerol kinase

Hydrolases: amidase

B4090_RS03210: amidase

smcogs: SMCOG1105: amidase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002103.2	0.66	other (other)	pulcherriminic acid	Bacillus subtilis subsp. subtilis str. 168
BGC0002631.2	0.53	ribosomal	Myxarylin	Pyxidicoccus fallax
BGC0000866.5	0.45	other (other)	polyhydroxyalkanoate	Burkholderia sp. DSM 9242
BGC0002482.2	0.40	other (other)	tjipanazole D, tjipanazole I, tjipanazole L, tjipanazole K, tjipanazole M	Symphyonema bifilamentata 97.28
BGC0000622.5	0.40	ribosomal	megacin	Bacillus megaterium
BGC0000719.5	0.37	saccharide	tobramycin	Streptoalloteichus hindustanus
BGC0000720.3	0.37	saccharide	tobramycin	Streptoalloteichus tenebrarius
BGC0002621.2	0.37	other (other)	angustmycin A, angustmycin B, angustmycin C, aristeromycin, arabinofuranosyladenine	Streptomyces angustmyceticus
BGC0002825.2	0.37	ribosomal	nocapeptin A	Nocardia terpenica IFM 0406
BGC0002594.2	0.36	PKS	orcinol, orsellinic acid	Fusarium graminearum PH-1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002103.2	0.66	other (other)	pulcherriminic acid	Bacillus subtilis subsp. subtilis str. 168
BGC0002631.2	0.53	ribosomal	Myxarylin	Pyxidicoccus fallax
BGC0000866.5	0.45	other (other)	polyhydroxyalkanoate	Burkholderia sp. DSM 9242
BGC0002482.2	0.40	other (other)	tjipanazole D, tjipanazole I, tjipanazole L, tjipanazole K, tjipanazole M	Symphyonema bifilamentata 97.28
BGC0000622.5	0.40	ribosomal	megacin	Bacillus megaterium
BGC0000719.5	0.37	saccharide	tobramycin	Streptoalloteichus hindustanus
BGC0000720.3	0.37	saccharide	tobramycin	Streptoalloteichus tenebrarius
BGC0002621.2	0.37	other (other)	angustmycin A, angustmycin B, angustmycin C, aristeromycin, arabinofuranosyladenine	Streptomyces angustmyceticus
BGC0002825.2	0.37	ribosomal	nocapeptin A	Nocardia terpenica IFM 0406
BGC0002594.2	0.36	PKS	orcinol, orsellinic acid	Fusarium graminearum PH-1

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 21.31 out of 25.88

Confidence: medium

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 21.79 out of 24.78

Confidence: medium

Additional weak hits (4):

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.57 out of 30.25

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 21.21 out of 28.14

Confidence: weak

CsoR

Description: Copper-responsive repressor
Species: Streptomyces lividans
Score: 22.48 out of 32.38

Confidence: weak

ZuR variant 2

Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 23.06 out of 33.14

Confidence: weak

Detailed domain annotation

Selected features only

Show module domains

TFBS Finder

TFBS definitions

Regulator	Description
LexA variant 2	Repressor of DNA damage response
PsrA	Oleic acid responsive regulator

NZ_LQYL01000003.1 - Region 2 - terpene-precursor

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Location: 278,223 - 299,104 nt. (total: 20,882 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Hydrolases: esterase hydrolase

B4090_RS04165: alpha/beta hydrolase domain-containing protein

smcogs: SMCOG1066: alpha/beta hydrolase domain-containing protein

B4090_RS04195: isochorismatase

smcogs: SMCOG1027: isochorismatase

B4090_RS04245: thioesterase superfamily protein

smcogs: SMCOG1144: thioesterase superfamily protein

Ligases: synthetase

B4090_RS04225: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000516.4	0.43	ribosomal	geobacillin II	Geobacillus thermodenitrificans
BGC0000205.3	0.35	PKS	bryostatin	Candidatus Endobugula sertula
BGC0000502.5	0.35	ribosomal	cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7	Bacillus cereus
BGC0002476.2	0.27	NRPS	enterobactin	Escherichia coli str. K-12 substr. MG1655
BGC0002432.2	0.27	NRPS	laterocidine	Brevibacillus laterosporus LMG 15441
BGC0002364.2	0.25	PKS	trichostatin RK	Streptomyces sp.
BGC0001200.4	0.25	PKS	lorneic acid A	Streptomyces sp. NBRC 109706
BGC0002672.2	0.25	PKS	saccharothrixin D, saccharothrixin E, saccharothrixin F, saccharothrixin G, saccharothrixin H, saccharothrixin I, saccharothrixin J, saccharothrixin K, saccharothrixin L, saccharothrixin M	Saccharothrix sp.
BGC0000806.5	0.25	saccharide	phosphonoglycans	Glycomyces sp. NRRL B-16210
BGC0001088.5	0.25	NRPS, PKS	albicidin	Xanthomonas albilineans

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000516.4	0.43	ribosomal	geobacillin II	Geobacillus thermodenitrificans
BGC0000205.3	0.35	PKS	bryostatin	Candidatus Endobugula sertula
BGC0000502.5	0.35	ribosomal	cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7	Bacillus cereus
BGC0002476.2	0.27	NRPS	enterobactin	Escherichia coli str. K-12 substr. MG1655
BGC0002432.2	0.27	NRPS	laterocidine	Brevibacillus laterosporus LMG 15441
BGC0002364.2	0.25	PKS	trichostatin RK	Streptomyces sp.
BGC0001200.4	0.25	PKS	lorneic acid A	Streptomyces sp. NBRC 109706
BGC0002672.2	0.25	PKS	saccharothrixin D, saccharothrixin E, saccharothrixin F, saccharothrixin G, saccharothrixin H, saccharothrixin I, saccharothrixin J, saccharothrixin K, saccharothrixin L, saccharothrixin M	Saccharothrix sp.
BGC0000806.5	0.25	saccharide	phosphonoglycans	Glycomyces sp. NRRL B-16210
BGC0001088.5	0.25	NRPS, PKS	albicidin	Xanthomonas albilineans

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor	FPP	C15	acyclic	PP
diterpene precursor	GGPP	C20	acyclic	PP
sesterterpene precursor	GFPP	C25	acyclic	PP
triterpene precursor	HPP	C30	acyclic	PP

Genes with terpene domains:

B4090_RS04225: PT_FPPS_like

Domain 1 (41 - 285): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: unknown

Reactions:: IPP, DMAPP → FPP; IPP, DMAPP → GGPP; IPP, DMAPP → GFPP; IPP, DMAPP → HPP

Transcription Factor Binding Sites

Binding sites found:

CcpA

Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 19.12 out of 20.97

Confidence: strong

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.31 out of 18.57

Confidence: strong

LexA variant 3

Description: Repressor of DNA damage response
Species: Escherichia coli str. K-12 substr. MG1655
Score: 24.84 out of 32.93

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.35 out of 26.06

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.58 out of 26.06

Confidence: medium

Additional weak hits (8):

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.22 out of 30.25

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 21.91 out of 28.14

Confidence: weak

ClgR

Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 20.80 out of 30.22

Confidence: weak

HgtR

Description: Hydrogen-dependent regulator
Species: Geobacter sulfurreducens PCA
Score: 24.21 out of 36.54

Confidence: weak

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 25.38 out of 32.74

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.72 out of 26.06

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.33 out of 26.06

Confidence: weak

ClgR

Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 21.37 out of 30.22

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
GFPP	Geranylfarnesyl diphosphate
GGPP	Geranylgeranyl diphosphate
HPP	Hexaprenyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

TFBS definitions

Regulator	Description
CcpA	Catabolite control protein A
LexA variant 3	Repressor of DNA damage response
MogR	Repressor of flagellar motility genes
ToxT	Regulator of MSHA biosynthesis

NZ_LQYL01000020.1 - Region 1 - NRPS

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Location: 192,811 - 220,520 nt. (total: 27,710 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Ligases: ligase

B4090_RS06670: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

Translocases: transporter

B4090_RS06650: sugar-binding lipoprotein

smcogs: SMCOG1143: sugar-binding lipoprotein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002135.2	0.71	NRPS	bovienimide A	Xenorhabdus bovienii SS-2004
BGC0001135.5	0.68	NRPS	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0000342.4	0.68	NRPS	enniatin	Fusarium equiseti
BGC0001833.4	0.68	NRPS	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825.4	0.68	NRPS	xenematide	Xenorhabdus nematophila AN6/1
BGC0001132.4	0.68	NRPS	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001166.5	0.68	NRPS	HC-toxin	Alternaria jesenskae
BGC0002286.3	0.66	NRPS	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001128.4	0.66	NRPS	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000307.4	0.66	NRPS	AbT1	Aureobasidium pullulans

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002135.2	0.71	NRPS	bovienimide A	Xenorhabdus bovienii SS-2004
BGC0001135.5	0.68	NRPS	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0000342.4	0.68	NRPS	enniatin	Fusarium equiseti
BGC0001833.4	0.68	NRPS	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825.4	0.68	NRPS	xenematide	Xenorhabdus nematophila AN6/1
BGC0001132.4	0.68	NRPS	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001166.5	0.68	NRPS	HC-toxin	Alternaria jesenskae
BGC0002286.3	0.66	NRPS	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001128.4	0.66	NRPS	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000307.4	0.66	NRPS	AbT1	Aureobasidium pullulans

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.31 out of 18.57

Confidence: strong

GnfM

Description: Regulator of nitrogen-fixation genes
Species: Geobacter sulfurreducens PCA
Score: 22.10 out of 27.55

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.60 out of 26.06

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 20.75 out of 27.78

Confidence: medium

Additional weak hits (2):

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.22 out of 30.25

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.08 out of 26.06

Confidence: weak

Module view

Legend

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS substrates

TFBS Finder

Predicted core structure(s)

For candidate cluster 1, location 192810 - 220520:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Gln - Leu)

Direct lookup in NORINE database: strict or relaxed

NRPS/PKS substrate predictions

B4090_RS06670: Gln - Leu

Search NORINE for peptide: strict or relaxed

AMP-binding (465..868): Gln

nrpys: Gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: gln (Gln)

Stachelhaus prediction details:

Stachelhaus sequence:: LGLAFDASVQQTDGLVGGETNVYGPTETCVDASS
Nearest Stachelhaus code(s):: Gln DAQDLGVVDK (100% 8Å match); Ile DAQDLGVVDK (76% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1513..1911): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: leu (Leu)

Stachelhaus prediction details:

Stachelhaus sequence:: TNASFDAFMFDGMILFGGELHMYGPSESTVFTTY
Nearest Stachelhaus code(s):: Leu DAFMLGMVFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

TFBS definitions

Regulator	Description
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
GnfM	Regulator of nitrogen-fixation genes
MogR	Repressor of flagellar motility genes
ToxT	Regulator of MSHA biosynthesis

NZ_LQYL01000021.1 - Region 1 - NRP-metallophore,NRPS

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Location: 180,216 - 231,969 nt. (total: 51,754 nt) Show pHMM detection rules used

NRP-metallophore: (VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))
NRPS: cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase electron transfer

B4090_RS07765: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

B4090_RS07835: flavodoxin

smcogs: SMCOG1134: flavodoxin

Hydrolases: hydrolase

B4090_RS07750: isochorismatase

smcogs: SMCOG1027: isochorismatase

Isomerases: isomerase

B4090_RS07760: isochorismate synthase

smcogs: SMCOG1018: isochorismate synthase

Ligases: ligase

B4090_RS07745: condensation domain-containing protein

smcogs: SMCOG1127: condensation domain-containing protein

B4090_RS07755: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002695.2	1.11	NRPS	bacillibactin, bacillibactin E, bacillibactin F	Bacillus sp. WMMC1349
BGC0001185.5	1.06	NRPS	bacillibactin	Bacillus velezensis FZB42
BGC0000401.5	1.06	NRPS	paenibactin	Paenibacillus elgii B69
BGC0000309.5	1.05	NRPS	bacillibactin	Bacillus subtilis subsp. subtilis str. 168
BGC0000343.5	0.86	NRPS	enterobactin	Pseudomonas sp. J465
BGC0002075.3	0.85	NRPS	pyreudione A, pyreudione B, pyreudione C, pyreudione D, pyreudione E	Pseudomonas fluorescens
BGC0001132.4	0.76	NRPS	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.4	0.76	NRPS	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825.4	0.75	NRPS	xenematide	Xenorhabdus nematophila AN6/1
BGC0001128.4	0.73	NRPS	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002695.2	0.82	NRPS	bacillibactin, bacillibactin E, bacillibactin F	Bacillus sp. WMMC1349
BGC0001185.5	0.80	NRPS	bacillibactin	Bacillus velezensis FZB42
BGC0000401.5	0.80	NRPS	paenibactin	Paenibacillus elgii B69
BGC0000309.5	0.80	NRPS	bacillibactin	Bacillus subtilis subsp. subtilis str. 168
BGC0000343.5	0.74	NRPS	enterobactin	Pseudomonas sp. J465
BGC0002075.3	0.74	NRPS	pyreudione A, pyreudione B, pyreudione C, pyreudione D, pyreudione E	Pseudomonas fluorescens
BGC0001132.4	0.70	NRPS	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.4	0.70	NRPS	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825.4	0.70	NRPS	xenematide	Xenorhabdus nematophila AN6/1
BGC0001128.4	0.69	NRPS	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.42 out of 26.06

Confidence: medium

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 26.61 out of 29.38

Confidence: strong

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 29.38 out of 29.38

Confidence: strong

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 17.48 out of 18.57

Confidence: strong

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.31 out of 18.57

Confidence: strong

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 23.80 out of 27.78

Confidence: medium

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 25.17 out of 29.38

Confidence: medium

CcpA

Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 17.67 out of 20.97

Confidence: medium

ANR

Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 20.54 out of 26.33

Confidence: medium

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 24.91 out of 29.38

Confidence: medium

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 23.66 out of 29.38

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 23.33 out of 27.78

Confidence: medium

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 24.43 out of 24.78

Confidence: strong

VqsM

Description: Regulator of quorum-sensing signalling systems
Species: Pseudomonas aeruginosa PAO1
Score: 18.42 out of 20.47

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.18 out of 28.19

Confidence: medium

Additional weak hits (19):

ClgR

Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 21.15 out of 30.22

Confidence: weak

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 22.49 out of 32.74

Confidence: weak

HexR

Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 22.41 out of 31.73

Confidence: weak

LuxO

Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 22.66 out of 26.12

Confidence: weak

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 21.10 out of 29.25

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 23.12 out of 29.38

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 21.80 out of 28.14

Confidence: weak

ANR

Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 20.06 out of 26.33

Confidence: weak

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 23.36 out of 32.74

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 21.73 out of 28.14

Confidence: weak

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 21.34 out of 29.25

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 21.28 out of 28.14

Confidence: weak

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 21.58 out of 30.25

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 20.96 out of 26.06

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 20.65 out of 26.06

Confidence: weak

HipB

Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 23.57 out of 33.73

Confidence: weak

NuR

Description: Nickel-responsive regulator
Species: Streptomyces coelicolor
Score: 23.25 out of 30.98

Confidence: weak

OsdR

Description: Development and stress management regulator
Species: Streptomyces coelicolor
Score: 20.57 out of 30.12

Confidence: weak

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 22.18 out of 29.25

Confidence: weak

Module view

Legend

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS substrates

TFBS Finder

Predicted core structure(s)

For candidate cluster 1, location 180215 - 231969:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Gly - Thr)

Direct lookup in NORINE database: strict or relaxed

NRPS/PKS substrate predictions

B4090_RS07745: Gly - Thr

Search NORINE for peptide: strict or relaxed

AMP-binding (465..861): Gly

nrpys: Gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: gly (Gly)

Stachelhaus prediction details:

Stachelhaus sequence:: FSMTFDISALELQALVGGETNLYGPTETTIWSTA
Nearest Stachelhaus code(s):: Gly DILQLGLIWK (97% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1521..1937): Thr

nrpys: Thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
Small clusters prediction:: thr (Thr)
Single AA prediction:: thr (Thr)

Stachelhaus prediction details:

Stachelhaus sequence:: LATHFDFSVWEGNQIFGGEINMYGITETTVHVSY
Nearest Stachelhaus code(s):: Thr DFWNIGMVHK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

B4090_RS07755: diOH-Bz

Search NORINE for peptide: strict or relaxed

AMP-binding (31..435): diOH-Bz

nrpys: diOH-Bz

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Small clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Single AA prediction:: dhb (diOH-Bz)

Stachelhaus prediction details:

Stachelhaus sequence:: SVSLYPLSSPGGGLQVGGAQQVYGMAEGLVNYTR
Nearest Stachelhaus code(s):: diOH-Bz PLPAQGVVNK (91% 8Å match)
Stachelhaus code match:: 90% (moderate)

TFBS definitions

Regulator	Description
ANR	Anaerobic transcriptional regulator
CcpA	Catabolite control protein A
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
FuR variant 1	Ferric Uptake Regulator
LexA variant 2	Repressor of DNA damage response
MogR	Repressor of flagellar motility genes
ToxT	Regulator of MSHA biosynthesis
VqsM	Regulator of quorum-sensing signalling systems
ZuR variant 1	Zinc-responsive repressor

NZ_LQYL01000021.1 - Region 2 - lassopeptide

BGC0002150.2 (MBO0654592.1):

Download region SVG

Location: 326,638 - 349,371 nt. (total: 22,734 nt) Show pHMM detection rules used

lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lasso peptides

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Hydrolases: hydrolase

B4090_RS08400: asparagine synthase (glutamine-hydrolyzing)

smcogs: SMCOG1177: asparagine synthase (glutamine-hydrolyzing)

Lyases: dehydratase

B4090_RS08440: NAD-dependent epimerase/dehydratase

smcogs: SMCOG1010: NAD-dependent epimerase/dehydratase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001552.3	0.50	ribosomal	citrulassin F	Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0001634.3	0.50	ribosomal	keywimysin	Streptomyces sp. NRRL F-5702
BGC0001549.3	0.49	ribosomal	citrulassin B	Streptomyces aurantiacus JA 4570
BGC0002289.2	0.48	ribosomal	Leepeptin	Streptomyces leeuwenhoekii
BGC0001551.4	0.48	ribosomal	citrulassin E	Streptomyces glaucescens
BGC0001639.3	0.46	ribosomal	klebsidin	Klebsiella pneumoniae
BGC0002064.2	0.45	ribosomal	felipeptin A2, felipeptin A1	Amycolatopsis sp. YIM 10
BGC0000623.3	0.42	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0002425.3	0.41	ribosomal	stlassin	Streptomyces sp.
BGC0000551.5	0.41	ribosomal	SapB	Streptomyces coelicolor A3(2)

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001552.3	0.50	ribosomal	citrulassin F	Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0001634.3	0.50	ribosomal	keywimysin	Streptomyces sp. NRRL F-5702
BGC0001549.3	0.49	ribosomal	citrulassin B	Streptomyces aurantiacus JA 4570
BGC0002289.2	0.48	ribosomal	Leepeptin	Streptomyces leeuwenhoekii
BGC0001551.4	0.48	ribosomal	citrulassin E	Streptomyces glaucescens
BGC0001639.3	0.46	ribosomal	klebsidin	Klebsiella pneumoniae
BGC0002064.2	0.45	ribosomal	felipeptin A2, felipeptin A1	Amycolatopsis sp. YIM 10
BGC0000623.3	0.42	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0002425.3	0.41	ribosomal	stlassin	Streptomyces sp.
BGC0000551.5	0.41	ribosomal	SapB	Streptomyces coelicolor A3(2)

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Lasso peptide predictions

Lassopeptide(s) for allorf_339390_339503

allorf_339390_339503

Leader:

MHDFRKIKEKRAGKLSFSTL

Full core:

CMMFFPRPRYHFSAGAF

Putative macrolactam:

antiSMASH-DB 4.0 matches for allorf_339390_339503

100.0%

NC_006322.1and 3 others:

NZ_CP033218.1 Lassopeptides: allorf_1614724_1614837_lassopeptideNZ_LQYL01000021.1 Lassopeptides: allorf_339390_339503_lassopeptideNZ_NIMP01000016.1 Lassopeptides: allorf_054045_054158_lassopeptide

Lassopeptides: allorf_3862232_3862345_lassopeptide

1

CMMFFPRPRYHFSAGAF

17

CMMFFPRPRYHFSAGAF

1

CMMFFPRPRYHFSAGAF

17

Lassopeptide(s) for allorf_340516_340641

allorf_340516_340641

Leader:

MTQMRKLESAQVKSYGSFLTVTL

Full core:

SKKSKPGDGKFGRGVKRG

Putative macrolactam:

SKKSKPGD

antiSMASH-DB 4.0 matches for allorf_340516_340641

100.0%

NC_006322.1and 72 others:

NC_021362.1 Lassopeptides: allorf_4042225_4042350_lassopeptideNZ_AP023088.1 Lassopeptides: allorf_0594187_0594312_lassopeptideNZ_AP025342.1 Lassopeptides: allorf_0961070_0961195_lassopeptideNZ_CABJBE010000002.1 Lassopeptides: allorf_334120_334245_lassopeptideNZ_CP010524.1 Lassopeptides: allorf_4061825_4061950_lassopeptideNZ_CP020352.1 Lassopeptides: allorf_4018279_4018404_lassopeptideNZ_CP023168.1 Lassopeptides: allorf_4201459_4201584_lassopeptideNZ_CP023665.1 Lassopeptides: allorf_4068832_4068957_lassopeptideNZ_CP033218.1 Lassopeptides: allorf_1613585_1613710_lassopeptideNZ_CP043761.1 Lassopeptides: allorf_6525412_6525540_lassopeptideNZ_CP049698.1 Lassopeptides: allorf_4058516_4058641_lassopeptideNZ_CP059494.1 Lassopeptides: allorf_3371934_3372059_lassopeptideNZ_CP068988.1 Lassopeptides: allorf_4020830_4020955_lassopeptideNZ_CP081825.1 Lassopeptides: allorf_1252758_1252886_lassopeptideNZ_CP083398.1 Lassopeptides: allorf_3088741_3088866_lassopeptideNZ_CP084682.1 Lassopeptides: allorf_4045630_4045755_lassopeptideNZ_CP090312.1 Lassopeptides: allorf_3988101_3988226_lassopeptideNZ_CP104093.1 Lassopeptides: allorf_0574703_0574828_lassopeptideNZ_CP110812.1 Lassopeptides: allorf_3160612_3160737_lassopeptideNZ_CP118744.1 Lassopeptides: allorf_4016420_4016545_lassopeptideNZ_JADNAZ010000003.1 Lassopeptides: allorf_147947_148072_lassopeptideNZ_JADNPI010000003.1 Lassopeptides: allorf_0346926_0347051_lassopeptideNZ_JAGTPZ010000028.1 Lassopeptides: allorf_0719212_0719337_lassopeptideNZ_JAHHXA010000001.1 Lassopeptides: allorf_234114_234239_lassopeptideNZ_JAJBZU010000003.1 Lassopeptides: allorf_0292203_0292328_lassopeptideNZ_JALAJD010000002.1 Lassopeptides: allorf_0333462_0333587_lassopeptideNZ_JALAJH010000002.1 Lassopeptides: allorf_205621_205746_lassopeptideNZ_JALAJI010000002.1 Lassopeptides: allorf_0713530_0713655_lassopeptideNZ_JALAJZ010000001.1 Lassopeptides: allorf_0700787_0700912_lassopeptideNZ_JALAKS010000001.1 Lassopeptides: allorf_053591_053716_lassopeptideNZ_JALALK010000001.1 Lassopeptides: allorf_0710239_0710364_lassopeptideNZ_JALALL010000012.1 Lassopeptides: allorf_159124_159249_lassopeptideNZ_JALALM010000005.1 Lassopeptides: allorf_0698852_0698977_lassopeptideNZ_JALALQ010000004.1 Lassopeptides: allorf_333021_333146_lassopeptideNZ_JALALU010000006.1 Lassopeptides: allorf_0339208_0339333_lassopeptideNZ_JALALZ010000002.1 Lassopeptides: allorf_0332050_0332175_lassopeptideNZ_JALAMC010000001.1 Lassopeptides: allorf_332573_332698_lassopeptideNZ_JALANK010000004.1 Lassopeptides: allorf_410616_410741_lassopeptideNZ_JALANL010000002.1 Lassopeptides: allorf_093009_093134_lassopeptideNZ_JALANM010000001.1 Lassopeptides: allorf_0332993_0333118_lassopeptideNZ_JALANO010000004.1 Lassopeptides: allorf_0347095_0347220_lassopeptideNZ_JALAON010000001.1 Lassopeptides: allorf_379211_379336_lassopeptideNZ_JALAOO010000003.1 Lassopeptides: allorf_069214_069339_lassopeptideNZ_JALAOQ010000004.1 Lassopeptides: allorf_0338021_0338146_lassopeptideNZ_JALAQL010000007.1 Lassopeptides: allorf_229865_229990_lassopeptideNZ_JALARN010000003.1 Lassopeptides: allorf_0700523_0700648_lassopeptideNZ_JALARO010000006.1 Lassopeptides: allorf_233062_233187_lassopeptideNZ_JALASJ010000005.1 Lassopeptides: allorf_0313268_0313393_lassopeptideNZ_JALAXE010000001.1 Lassopeptides: allorf_336072_336197_lassopeptideNZ_JALAXI010000010.1 Lassopeptides: allorf_327187_327312_lassopeptideNZ_JALAXO010000001.1 Lassopeptides: allorf_345480_345605_lassopeptideNZ_JALAXW010000003.1 Lassopeptides: allorf_0337796_0337921_lassopeptideNZ_JALAYB010000003.1 Lassopeptides: allorf_0339260_0339385_lassopeptideNZ_JALAYQ010000005.1 Lassopeptides: allorf_0332651_0332776_lassopeptideNZ_JALAYR010000003.1 Lassopeptides: allorf_0325317_0325442_lassopeptideNZ_JALHKQ010000002.1 Lassopeptides: allorf_0338015_0338140_lassopeptideNZ_KE819960.1 Lassopeptides: allorf_0718627_0718752_lassopeptideNZ_KN125579.1 Lassopeptides: allorf_1553823_1553948_lassopeptideNZ_LQYL01000021.1 Lassopeptides: allorf_340516_340641_lassopeptideNZ_MRBL01000001.1 Lassopeptides: allorf_147911_148036_lassopeptideNZ_MUEI01000002.1 Lassopeptides: allorf_0340674_0340799_lassopeptideNZ_NIJN01000012.1 Lassopeptides: allorf_433741_433866_lassopeptideNZ_NIKH01000013.1 Lassopeptides: allorf_0336426_0336551_lassopeptideNZ_NIKK01000036.1 Lassopeptides: allorf_265538_265663_lassopeptideNZ_NIKT01000037.1 Lassopeptides: allorf_071185_071310_lassopeptideNZ_NIKU01000018.1 Lassopeptides: allorf_0720911_0721036_lassopeptideNZ_NILF01000062.1 Lassopeptides: allorf_345658_345783_lassopeptideNZ_NIMP01000016.1 Lassopeptides: allorf_052906_053031_lassopeptideNZ_NKBC01000013.1 Lassopeptides: allorf_192723_192848_lassopeptideNZ_QXII01000003.1 Lassopeptides: allorf_0338451_0338576_lassopeptideNZ_RSBH01000002.1 Lassopeptides: allorf_192912_193037_lassopeptideNZ_RZIR01000001.1 Lassopeptides: allorf_4050643_4050768_lassopeptide

Lassopeptides: allorf_3863359_3863484_lassopeptide

1

SKKSKPGDGKFGRGVKRG

18

SKKSKPGDGKFGRGVKRG

1

SKKSKPGDGKFGRGVKRG

18

83.3%

NZ_CP023481.1and 1 other:

NZ_JAQCPU010000002.1 Lassopeptides: allorf_328794_328907_lassopeptide

Lassopeptides: allorf_2680773_2680886_lassopeptide

1

SKKSKPGDGKFGRGVK

16

SKKSKPGDGKFGRG K

1

SKKSKPGDGKFGRGKK

16

57.1%

NZ_NBBB01000032.1and 3 others:

NZ_NBBB01000032.1 Lassopeptides: allorf_05793_05924_lassopeptideNZ_NUOG01000005.1 Lassopeptides: COE07_RS28160_lassopeptideNZ_NUOG01000005.1 Lassopeptides: COE07_RS28155_lassopeptide

Lassopeptides: allorf_06132_06263_lassopeptide

1

SKKSKPGDGKFGRGVKRG

18

+K KPGDGK G+G KRG

1

AKSGKPGDGKHGKG-KRG

17

with 4 more sequence matches

50.0%

NZ_CP036072.1and 6 others:

NZ_FMBE01000014.1 Lassopeptides: allorf_125136_125252_lassopeptideNZ_FMBH01000039.1 Lassopeptides: allorf_20814_20930_lassopeptideNZ_KB976981.1 Lassopeptides: allorf_264278_264394_lassopeptideNZ_LDJQ01000026.1 Lassopeptides: allorf_16163_16279_lassopeptideNZ_NVLX01000026.1 Lassopeptides: allorf_29444_29560_lassopeptideNZ_VEJP01000004.1 Lassopeptides: allorf_148224_148340_lassopeptide

Lassopeptides: allorf_073459_073575_lassopeptide

1

SKKSKPGDGKFGRGVKR

17

+K KPGDG +GV+R

1

AKTKKPGDGTRAKGVRR

17

47.4%

NZ_CP036072.1and 20 others:

NZ_CP036072.1 Lassopeptides: allorf_073148_073267_lassopeptideNZ_CP036072.1 Lassopeptides: allorf_072992_073111_lassopeptideNZ_CP036072.1 Lassopeptides: allorf_072788_072955_lassopeptideNZ_FMBE01000014.1 Lassopeptides: allorf_124981_125100_lassopeptideNZ_FMBE01000014.1 Lassopeptides: allorf_124825_124944_lassopeptideNZ_FMBE01000014.1 Lassopeptides: allorf_124621_124788_lassopeptideNZ_FMBH01000039.1 Lassopeptides: allorf_21278_21445_lassopeptideNZ_FMBH01000039.1 Lassopeptides: allorf_21122_21241_lassopeptideNZ_FMBH01000039.1 Lassopeptides: allorf_20966_21085_lassopeptideNZ_KB976981.1 Lassopeptides: allorf_264123_264242_lassopeptideNZ_LDJQ01000026.1 Lassopeptides: allorf_16627_16794_lassopeptideNZ_LDJQ01000026.1 Lassopeptides: allorf_16471_16590_lassopeptideNZ_LDJQ01000026.1 Lassopeptides: allorf_16315_16434_lassopeptideNZ_NVLX01000026.1 Lassopeptides: allorf_29907_30074_lassopeptideNZ_NVLX01000026.1 Lassopeptides: allorf_29752_29871_lassopeptideNZ_NVLX01000026.1 Lassopeptides: allorf_29596_29715_lassopeptideNZ_VEFJ01000007.1 Lassopeptides: allorf_022530_022649_lassopeptideNZ_VEFJ01000007.1 Lassopeptides: allorf_022374_022493_lassopeptideNZ_VEFJ01000007.1 Lassopeptides: allorf_022171_022338_lassopeptideNZ_VEJP01000004.1 Lassopeptides: allorf_148376_148543_lassopeptide

Lassopeptides: allorf_073304_073423_lassopeptide

1

SKKSKPGDGKFGRGVKRG

18

+KK+KPGDG +G+++G

1

AKKNKPGDGTRTKGIRKG

18

42.9%

NZ_CP085880.1:

Lassopeptides: FH508_RS23935_lassopeptide

1

SKKSKPGDG

9

SKKSKPGDG

1

SKKSKPGDG

9

21.9%

NZ_CP084203.1:

Lanthipeptides: allorf_0587605_0587784_lanthipeptide

1

SKKSKPGDGKFGRGVKRG

18

++++ PGD GR V G

15

AERAVPGDDGPGRAVSAG

32

MIBiG 4.0 matches for allorf_340516_340641

66.7%

Lasso peptide: triculamin

1

SKKSKPGDGKFGRGVK

16

SKKSKPGDG G+GV+

1

SKKSKPGDGIRGKGVR

16

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Transcription Factor Binding Sites

Binding sites found:

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.12 out of 23.79

Confidence: medium

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 27.50 out of 30.25

Confidence: strong

CcpA

Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 18.15 out of 20.97

Confidence: medium

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 23.79 out of 30.25

Confidence: medium

ANR

Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 21.28 out of 26.33

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 23.24 out of 28.19

Confidence: medium

Additional weak hits (4):

CelR

Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 20.52 out of 30.11

Confidence: weak

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 23.74 out of 32.74

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 21.83 out of 29.38

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.22 out of 26.06

Confidence: weak

Lasso peptides

RREFinder

TFBS Finder

Core peptide predictions

allorf_339390_339503 - Class II: Cleavage pHMM score: -7.70; RODEO score: 19; Monoisotopic mass: 2045.9 Da; Molecular weight: 2047.4 Da; Number of bridges: 0
allorf_340516_340641 - Class II: Cleavage pHMM score: -6.40; RODEO score: 16; Monoisotopic mass: 1870.1 Da; Molecular weight: 1871.1 Da; Number of bridges: 0

RRE predictions

: RRE type: Stand_Alone_Lasso_RRE; Location: 4 - 86; Score: 32.3

TFBS definitions

Regulator	Description
ANR	Anaerobic transcriptional regulator
CcpA	Catabolite control protein A
ColR	Phenol-responsive regulator
IolR	Regulator of the inositol catabolism
ZuR variant 1	Zinc-responsive repressor

NZ_LQYL01000021.1 - Region 3 - lanthipeptide-class-ii

BGC0001229.4 (SBI_06989):

Download region SVG

Location: 408,005 - 434,966 nt. (total: 26,962 nt) Show pHMM detection rules used

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Hydrolases: protease

B4090_RS08815: alkaline serine protease, subtilase family

smcogs: SMCOG1075: alkaline serine protease, subtilase family

Lyases: cyclase

B4090_RS08825: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

B4090_RS08840: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000525.5	1.00	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0000517.4	0.67	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0000504.5	0.57	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0002698.2	0.55	ribosomal	phaeornamide	Pseudophaeobacter arcticus DSM 23566
BGC0000554.4	0.55	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000500.5	0.54	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000623.3	0.54	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0000516.4	0.54	ribosomal	geobacillin II	Geobacillus thermodenitrificans
BGC0000519.4	0.53	ribosomal	labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3	Actinomadura namibiensis
BGC0001229.4	0.53	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000525.5	1.00	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0000517.4	0.67	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0000504.5	0.57	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0002698.2	0.55	ribosomal	phaeornamide	Pseudophaeobacter arcticus DSM 23566
BGC0000554.4	0.55	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000500.5	0.54	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000623.3	0.54	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0000516.4	0.54	ribosomal	geobacillin II	Geobacillus thermodenitrificans
BGC0000519.4	0.53	ribosomal	labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3	Actinomadura namibiensis
BGC0001229.4	0.53	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for B4090_RS08825

B4090_RS08830

Leader:

MKTMKNSAAREAFKGANHPAGMVSEEELKALVGG

Core:

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

Core with dehydrations:

NDVNPEDhbDhbPADhbDhbDhaDhaWDhbCysIDhbAGVDhbVDhaADhaLCysPDhbDhbKCysDhbDhaRCys

antiSMASH-DB 4.0 matches for B4090_RS08830

100.0%

NC_006322.1and 7 others:

NC_006322.1 Lanthipeptides: BLI_RS20290_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide

Lanthipeptides: BLI_RS20290_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

87.2%

NZ_CP009288.1and 3 others:

NZ_CP009288.1 Lanthipeptides: PDUR_RS29295_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptide

Lanthipeptides: PDUR_RS29295_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DVNPETT TTSSWTCITAGVTVSASLCPTTKCTS+C

2

GDVNPETTILTTSSWTCITAGVTVSASLCPTTKCTSQC

39

71.1%

NZ_CM000721.1and 9 others:

NZ_CP015591.1 Lanthipeptides: A7A70_RS27555_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29360_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_NUBO01000052.1 Lanthipeptides: CN575_RS29785_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide

Lanthipeptides: BCERE0010_RS29355_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DVNPETTPAT T I A + V+ASLCPTTKCTSRC

1

GDVNPETTPAT---PTIIGATIAVTASLCPTTKCTSRC

35

with 133 more sequence matches

Only the first 10 are displayed here.

69.2%

NZ_CP009280.1and 1 other:

NZ_CP009280.1 Lanthipeptides: P40081_RS37160_lanthipeptide

Lanthipeptides: P40081_RS37160_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DVNPETTP TTSSW C+ V +SA+LCPTTKCTS+C

2

GDVNPETTPLTTSSWPCVIGAVDISANLCPTTKCTSKC

39

60.5%

NZ_CP015591.1and 15 others:

NZ_CP078085.1 Lanthipeptides: KU891_RS29355_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29350_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29345_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29340_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29335_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptide

Lanthipeptides: A7A70_RS27550_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DVNPETTPAT T + A + + S+CPTTKCTSRC

1

GDVNPETTPAT---PTIVEATIAATVSICPTTKCTSRC

35

60.5%

NZ_CP085411.1and 1 other:

NZ_CP085411.1 Lanthipeptides: LIT28_RS29915_lanthipeptide

Lanthipeptides: LIT28_RS29915_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DVNPETTP T + T + G T+S +CPTTKCTSRC

1

GDVNPETTPTTATVTT-VLVGATIS--VCPTTKCTSRC

35

60.5%

NZ_QNUC01000031.1and 1 other:

NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23045_lanthipeptide

Lanthipeptides: DN396_RS23045_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DVNPETTP T + T + G T+S +CPTTKCTSRC

1

GDVNPETTPTTATVTT-VLVGATIS--ICPTTKCTSRC

35

57.9%

NC_018499.1and 5 others:

NC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27845_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptide

Lanthipeptides: BCK_RS27845_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DVNPETTPAT + V VS +CPTTKCTS+C

1

GDVNPETTPATPTI-------VAVSLGICPTTKCTSKC

31

57.9%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide

Lanthipeptides: EXW52_RS27205_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DV+PETTPAT T V +S LCPTTKCTS+C

1

GDVSPETTPATP------TIVVAISVGLCPTTKCTSKC

32

57.9%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20140_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DV+PETTPAT T V +S LCPTTKCTS+C

1

GDVSPETTPATP------TIVVGISVGLCPTTKCTSKC

32

55.3%

NZ_CP006058.1and 25 others:

NZ_CP006058.1 Lanthipeptides: BAMY6639_RS19790_lanthipeptideNZ_CP021892.1 Lanthipeptides: S100333_RS03330_lanthipeptideNZ_CP021892.1 Lanthipeptides: S100333_RS03330_lanthipeptideNZ_CP026533.1 Lanthipeptides: C3438_RS12920_lanthipeptideNZ_CP026533.1 Lanthipeptides: C3438_RS12920_lanthipeptideNZ_CP028961.1 Lanthipeptides: DBK22_RS18410_lanthipeptideNZ_CP028961.1 Lanthipeptides: DBK22_RS18410_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS14705_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS14705_lanthipeptideNZ_CP044132.1 Lanthipeptides: F5K02_RS03575_lanthipeptideNZ_CP044132.1 Lanthipeptides: F5K02_RS03575_lanthipeptideNZ_CP061087.1 Lanthipeptides: IAR44_RS03180_lanthipeptideNZ_CP061087.1 Lanthipeptides: IAR44_RS03180_lanthipeptideNZ_CP063276.1 Lanthipeptides: IM743_RS02810_lanthipeptideNZ_CP063276.1 Lanthipeptides: IM743_RS02810_lanthipeptideNZ_CP065791.1 Lanthipeptides: I8N73_RS03410_lanthipeptideNZ_CP065791.1 Lanthipeptides: I8N73_RS03410_lanthipeptideNZ_CP074348.1 Lanthipeptides: KHA74_RS03215_lanthipeptideNZ_CP074348.1 Lanthipeptides: KHA74_RS03215_lanthipeptideNZ_CP083943.1 Lanthipeptides: LCH16_RS03235_lanthipeptideNZ_CP083943.1 Lanthipeptides: LCH16_RS03235_lanthipeptideNZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10980_lanthipeptideNZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10980_lanthipeptideNZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15460_lanthipeptideNZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15460_lanthipeptide

Lanthipeptides: BAMY6639_RS19790_lanthipeptide

2

DVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DV P TTP SS C GV V+A+ CP+TKCTS C

2

DVTPHTTP---SSLPC---GVFVTAAFCPSTKCTSSC

32

55.3%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27165_lanthipeptide

Lanthipeptides: EXW52_RS27165_lanthipeptide

2

DVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DVNPET PAT T I A +T LCP+ CTSRC

2

DVNPETIPATA---TPILANLT--KELCPSIPCTSRC

33

52.6%

NZ_CP036019.1and 7 others:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27190_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptide

Lanthipeptides: EXW52_RS27190_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DV+PETTPAT T V +S LCPT +CTS+C

1

GDVSPETTPATP------TIVVAISVGLCPTNRCTSKC

32

MIBiG 4.0 matches for B4090_RS08830

55.3%

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

7

TTPATTS---SWTCITAGVTV--SASLCPTTKCTSRC

38

T PA T I AGV V SA+ CPTTKCTSRC

1

TDPAVTGLILGIVAIQAGVAVGVSAAFCPTTKCTSRC

37

23.7%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

28

LCPTTKCTSRC

38

CPTTKCTS+C

16

FCPTTKCTSKC

26

B4090_RS08835

Leader:

MSKKEMILSWKNPMYRTESSYHPAGNILKELQEEEQHSIAGG

Core:

TITLSTCAILSKPLGNNGYLCTVTKECMPSCN

Core with dehydrations:

DhbIDhbLDhaDhbCysAILDhaKPLGNNGYLCysDhbVDhbKECysMPDhaCysN

antiSMASH-DB 4.0 matches for B4090_RS08835

100.0%

NC_006322.1and 7 others:

NC_006322.1 Lanthipeptides: BLI_RS20295_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07805_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07805_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08835_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08835_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11865_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11865_lanthipeptide

Lanthipeptides: BLI_RS20295_lanthipeptide

1

TITLSTCAILSKPLGNNGYLCTVTKECMPSCN

32

TITLSTCAILSKPLGNNGYLCTVTKECMPSCN

1

TITLSTCAILSKPLGNNGYLCTVTKECMPSCN

32

58.3%

NZ_CP009288.1and 3 others:

NZ_CP009288.1 Lanthipeptides: PDUR_RS25150_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01580_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01580_lanthipeptide

Lanthipeptides: PDUR_RS25150_lanthipeptide

1

TITLSTCAILSKPLGNNGYLCTVTKECMPSCN

32

T+T ST ++S LGNNG++CT TKECMPSCN

5

TLTTSTSILISMTLGNNGWVCTATKECMPSCN

36

56.2%

NZ_CP015591.1and 19 others:

NZ_CP015591.1 Lanthipeptides: A7A70_RS27560_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29375_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29370_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29365_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29955_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29950_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29945_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29955_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29950_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29945_lanthipeptideNZ_JACYOF010000027.1 Lanthipeptides: IGI01_RS29005_lanthipeptideNZ_NUBO01000052.1 Lanthipeptides: CN575_RS29780_lanthipeptideNZ_NVJC01000007.1 Lanthipeptides: COM38_RS07400_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23035_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23030_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23025_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23035_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23030_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23025_lanthipeptide

Lanthipeptides: A7A70_RS27565_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS LGNNG CT+TKECMPSCN

10

LSSWLGNNGGYCTLTKECMPSCN

32

with 103 more sequence matches

Only the first 10 are displayed here.

56.2%

NZ_CP050134.2and 3 others:

NZ_EQ973330.1 Lanthipeptides: CORMATOL_RS10565_lanthipeptideNZ_LR134504.1 Lanthipeptides: EL293_RS07240_lanthipeptideNZ_LR134504.1 Lanthipeptides: EL293_RS07240_lanthipeptide

Lanthipeptides: HBA49_RS00770_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS+ LGNNG CT+TKECMPSCN

1

LSRLLGNNGRWCTITKECMPSCN

23

53.1%

NC_018499.1and 10 others:

NC_018499.1 Lanthipeptides: BCK_RS27855_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27850_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27860_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27855_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27850_lanthipeptideNZ_JAOPQW010000026.1 Lanthipeptides: OCD10_RS25275_lanthipeptideNZ_JAOPQW010000026.1 Lanthipeptides: OCD10_RS25270_lanthipeptideNZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27570_lanthipeptideNZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27565_lanthipeptideNZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27560_lanthipeptide

Lanthipeptides: BCK_RS27860_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS LGN G CT+TKECMPSCN

10

LSSWLGNKGGYCTLTKECMPSCN

32

52.8%

NZ_CP009280.1and 1 other:

NZ_CP009280.1 Lanthipeptides: P40081_RS01820_lanthipeptide

Lanthipeptides: P40081_RS01820_lanthipeptide

1

TITLSTCAILSKPLGNNGYLCTVTKECMPSCN

32

T+T ST +S+ LGN+G++CT +KECMPSCN

5

TLTTSTSIFISRGLGNDGWVCTWSKECMPSCN

36

50.0%

NZ_CP036019.1and 9 others:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27210_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27215_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27210_lanthipeptideNZ_JANIOB010000033.1 Lanthipeptides: NQ113_RS28005_lanthipeptideNZ_JH791925.1 Lanthipeptides: IE3_RS28545_lanthipeptideNZ_NUML01000015.1 Lanthipeptides: COD66_RS20150_lanthipeptideNZ_NUML01000015.1 Lanthipeptides: COD66_RS20145_lanthipeptideNZ_NUVR01000040.1 Lanthipeptides: COI88_RS26655_lanthipeptideNZ_NUVR01000040.1 Lanthipeptides: COI88_RS26650_lanthipeptide

Lanthipeptides: EXW52_RS27215_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS LGN G CT+TKECM SCN

10

LSSWLGNKGGYCTLTKECMSSCN

32

50.0%

NZ_CP042598.1and 2 others:

NZ_RKNR01000012.1 Lanthipeptides: EGW35_RS11615_lanthipeptideNZ_RKNR01000012.1 Lanthipeptides: EGW35_RS11615_lanthipeptide

Lanthipeptides: FUT28_RS13825_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS LGN G CT TKECMPSCN

12

LSDYLGNTGGWCTATKECMPSCN

34

50.0%

NZ_CP084530.1and 1 other:

NZ_CP084530.1 Lanthipeptides: LDO05_RS02075_lanthipeptide

Lanthipeptides: LDO05_RS02075_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS LGNNG CT+TKEC SCN

8

LSNYLGNNGGWCTLTKECQRSCN

30

50.0%

NZ_JADPDT010000005.1and 1 other:

NZ_JADPDT010000005.1 Lanthipeptides: I4V19_RS09885_lanthipeptide

Lanthipeptides: I4V19_RS09885_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS LGN G CT TKECMPSCN

12

LSDFLGNTGGWCTATKECMPSCN

34

50.0%

NZ_LT630004.1:

Lanthipeptides: BQ5796_RS17475_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS LGN+G CT+T ECMPSCN

2

LSSLLGNDGKFCTLTVECMPSCN

24

46.9%

NC_002570.2and 3 others:

NC_002570.2 Lanthipeptides: AYT26_RS02480_lanthipeptideNZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptideNZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptide

Lanthipeptides: AYT26_RS02480_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

+S LGN G CT+T ECMPSCN

10

ISCRLGNKGAYCTLTVECMPSCN

32

46.9%

NZ_AKXV01000031.1and 4 others:

NZ_AKXV01000031.1 Lanthipeptides: Y19_RS0109895_lanthipeptideNZ_JABBGE010000004.1 Lanthipeptides: HHL19_RS13545_lanthipeptideNZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptideNZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptide

Lanthipeptides: Y19_RS0109895_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS LGN G CT+TKEC P+CN

8

LSDFLGNQGGWCTLTKECQPNCN

30

MIBiG 4.0 matches for B4090_RS08835

50.0%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS LGNNG CT+TKEC P+CN

8

LSNALGNNGGWCTLTKECQPNCN

30

46.9%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

10

LSKPLGNNGYLCTVTKECMPSCN

32

+S LGN G CT+T ECMPSCN

6

ISCRLGNKGAYCTLTVECMPSCN

28

20.5%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

21

CTVTKECMPSCN

32

CT++KEC P+CN

28

CTLSKECQPNCN

39

Lanthipeptide(s) for B4090_RS08840

B4090_RS08830

Leader:

MKTMKNSAAREAFKGANHPAGMVSEEELKALVGG

Core:

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

Core with dehydrations:

NDVNPEDhbDhbPADhbDhbDhaDhaWDhbCysIDhbAGVDhbVDhaADhaLCysPDhbDhbKCysDhbDhaRCys

antiSMASH-DB 4.0 matches for B4090_RS08830

100.0%

NC_006322.1and 7 others:

NC_006322.1 Lanthipeptides: BLI_RS20290_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide

Lanthipeptides: BLI_RS20290_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

87.2%

NZ_CP009288.1and 3 others:

NZ_CP009288.1 Lanthipeptides: PDUR_RS29295_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptide

Lanthipeptides: PDUR_RS29295_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DVNPETT TTSSWTCITAGVTVSASLCPTTKCTS+C

2

GDVNPETTILTTSSWTCITAGVTVSASLCPTTKCTSQC

39

71.1%

NZ_CM000721.1and 9 others:

NZ_CP015591.1 Lanthipeptides: A7A70_RS27555_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29360_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_NUBO01000052.1 Lanthipeptides: CN575_RS29785_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide

Lanthipeptides: BCERE0010_RS29355_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DVNPETTPAT T I A + V+ASLCPTTKCTSRC

1

GDVNPETTPAT---PTIIGATIAVTASLCPTTKCTSRC

35

with 133 more sequence matches

Only the first 10 are displayed here.

69.2%

NZ_CP009280.1and 1 other:

NZ_CP009280.1 Lanthipeptides: P40081_RS37160_lanthipeptide

Lanthipeptides: P40081_RS37160_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DVNPETTP TTSSW C+ V +SA+LCPTTKCTS+C

2

GDVNPETTPLTTSSWPCVIGAVDISANLCPTTKCTSKC

39

60.5%

NZ_CP015591.1and 15 others:

NZ_CP078085.1 Lanthipeptides: KU891_RS29355_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29350_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29345_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29340_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29335_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptide

Lanthipeptides: A7A70_RS27550_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DVNPETTPAT T + A + + S+CPTTKCTSRC

1

GDVNPETTPAT---PTIVEATIAATVSICPTTKCTSRC

35

60.5%

NZ_CP085411.1and 1 other:

NZ_CP085411.1 Lanthipeptides: LIT28_RS29915_lanthipeptide

Lanthipeptides: LIT28_RS29915_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DVNPETTP T + T + G T+S +CPTTKCTSRC

1

GDVNPETTPTTATVTT-VLVGATIS--VCPTTKCTSRC

35

60.5%

NZ_QNUC01000031.1and 1 other:

NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23045_lanthipeptide

Lanthipeptides: DN396_RS23045_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DVNPETTP T + T + G T+S +CPTTKCTSRC

1

GDVNPETTPTTATVTT-VLVGATIS--ICPTTKCTSRC

35

57.9%

NC_018499.1and 5 others:

NC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27845_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptide

Lanthipeptides: BCK_RS27845_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DVNPETTPAT + V VS +CPTTKCTS+C

1

GDVNPETTPATPTI-------VAVSLGICPTTKCTSKC

31

57.9%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide

Lanthipeptides: EXW52_RS27205_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DV+PETTPAT T V +S LCPTTKCTS+C

1

GDVSPETTPATP------TIVVAISVGLCPTTKCTSKC

32

57.9%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20140_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DV+PETTPAT T V +S LCPTTKCTS+C

1

GDVSPETTPATP------TIVVGISVGLCPTTKCTSKC

32

55.3%

NZ_CP006058.1and 25 others:

NZ_CP006058.1 Lanthipeptides: BAMY6639_RS19790_lanthipeptideNZ_CP021892.1 Lanthipeptides: S100333_RS03330_lanthipeptideNZ_CP021892.1 Lanthipeptides: S100333_RS03330_lanthipeptideNZ_CP026533.1 Lanthipeptides: C3438_RS12920_lanthipeptideNZ_CP026533.1 Lanthipeptides: C3438_RS12920_lanthipeptideNZ_CP028961.1 Lanthipeptides: DBK22_RS18410_lanthipeptideNZ_CP028961.1 Lanthipeptides: DBK22_RS18410_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS14705_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS14705_lanthipeptideNZ_CP044132.1 Lanthipeptides: F5K02_RS03575_lanthipeptideNZ_CP044132.1 Lanthipeptides: F5K02_RS03575_lanthipeptideNZ_CP061087.1 Lanthipeptides: IAR44_RS03180_lanthipeptideNZ_CP061087.1 Lanthipeptides: IAR44_RS03180_lanthipeptideNZ_CP063276.1 Lanthipeptides: IM743_RS02810_lanthipeptideNZ_CP063276.1 Lanthipeptides: IM743_RS02810_lanthipeptideNZ_CP065791.1 Lanthipeptides: I8N73_RS03410_lanthipeptideNZ_CP065791.1 Lanthipeptides: I8N73_RS03410_lanthipeptideNZ_CP074348.1 Lanthipeptides: KHA74_RS03215_lanthipeptideNZ_CP074348.1 Lanthipeptides: KHA74_RS03215_lanthipeptideNZ_CP083943.1 Lanthipeptides: LCH16_RS03235_lanthipeptideNZ_CP083943.1 Lanthipeptides: LCH16_RS03235_lanthipeptideNZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10980_lanthipeptideNZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10980_lanthipeptideNZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15460_lanthipeptideNZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15460_lanthipeptide

Lanthipeptides: BAMY6639_RS19790_lanthipeptide

2

DVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DV P TTP SS C GV V+A+ CP+TKCTS C

2

DVTPHTTP---SSLPC---GVFVTAAFCPSTKCTSSC

32

55.3%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27165_lanthipeptide

Lanthipeptides: EXW52_RS27165_lanthipeptide

2

DVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DVNPET PAT T I A +T LCP+ CTSRC

2

DVNPETIPATA---TPILANLT--KELCPSIPCTSRC

33

52.6%

NZ_CP036019.1and 7 others:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27190_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptide

Lanthipeptides: EXW52_RS27190_lanthipeptide

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

DV+PETTPAT T V +S LCPT +CTS+C

1

GDVSPETTPATP------TIVVAISVGLCPTNRCTSKC

32

MIBiG 4.0 matches for B4090_RS08830

55.3%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

7

TTPATTS---SWTCITAGVTV--SASLCPTTKCTSRC

38

T PA T I AGV V SA+ CPTTKCTSRC

1

TDPAVTGLILGIVAIQAGVAVGVSAAFCPTTKCTSRC

37

23.7%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

28

LCPTTKCTSRC

38

CPTTKCTS+C

16

FCPTTKCTSKC

26

B4090_RS08835

Leader:

MSKKEMILSWKNPMYRTESSYHPAGNILKELQEEEQHSIAGG

Core:

TITLSTCAILSKPLGNNGYLCTVTKECMPSCN

Core with dehydrations:

DhbIDhbLDhaDhbCysAILDhaKPLGNNGYLCysDhbVDhbKECysMPDhaCysN

antiSMASH-DB 4.0 matches for B4090_RS08835

100.0%

NC_006322.1and 7 others:

NC_006322.1 Lanthipeptides: BLI_RS20295_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07805_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07805_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08835_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08835_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11865_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11865_lanthipeptide

Lanthipeptides: BLI_RS20295_lanthipeptide

1

TITLSTCAILSKPLGNNGYLCTVTKECMPSCN

32

TITLSTCAILSKPLGNNGYLCTVTKECMPSCN

1

TITLSTCAILSKPLGNNGYLCTVTKECMPSCN

32

58.3%

NZ_CP009288.1and 3 others:

NZ_CP009288.1 Lanthipeptides: PDUR_RS25150_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01580_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01580_lanthipeptide

Lanthipeptides: PDUR_RS25150_lanthipeptide

1

TITLSTCAILSKPLGNNGYLCTVTKECMPSCN

32

T+T ST ++S LGNNG++CT TKECMPSCN

5

TLTTSTSILISMTLGNNGWVCTATKECMPSCN

36

56.2%

NZ_CP015591.1and 19 others:

NZ_CP015591.1 Lanthipeptides: A7A70_RS27560_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29375_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29370_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29365_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29955_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29950_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29945_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29955_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29950_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29945_lanthipeptideNZ_JACYOF010000027.1 Lanthipeptides: IGI01_RS29005_lanthipeptideNZ_NUBO01000052.1 Lanthipeptides: CN575_RS29780_lanthipeptideNZ_NVJC01000007.1 Lanthipeptides: COM38_RS07400_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23035_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23030_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23025_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23035_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23030_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23025_lanthipeptide

Lanthipeptides: A7A70_RS27565_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS LGNNG CT+TKECMPSCN

10

LSSWLGNNGGYCTLTKECMPSCN

32

with 103 more sequence matches

Only the first 10 are displayed here.

56.2%

NZ_CP050134.2and 3 others:

NZ_EQ973330.1 Lanthipeptides: CORMATOL_RS10565_lanthipeptideNZ_LR134504.1 Lanthipeptides: EL293_RS07240_lanthipeptideNZ_LR134504.1 Lanthipeptides: EL293_RS07240_lanthipeptide

Lanthipeptides: HBA49_RS00770_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS+ LGNNG CT+TKECMPSCN

1

LSRLLGNNGRWCTITKECMPSCN

23

53.1%

NC_018499.1and 10 others:

NC_018499.1 Lanthipeptides: BCK_RS27855_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27850_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27860_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27855_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27850_lanthipeptideNZ_JAOPQW010000026.1 Lanthipeptides: OCD10_RS25275_lanthipeptideNZ_JAOPQW010000026.1 Lanthipeptides: OCD10_RS25270_lanthipeptideNZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27570_lanthipeptideNZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27565_lanthipeptideNZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27560_lanthipeptide

Lanthipeptides: BCK_RS27860_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS LGN G CT+TKECMPSCN

10

LSSWLGNKGGYCTLTKECMPSCN

32

52.8%

NZ_CP009280.1and 1 other:

NZ_CP009280.1 Lanthipeptides: P40081_RS01820_lanthipeptide

Lanthipeptides: P40081_RS01820_lanthipeptide

1

TITLSTCAILSKPLGNNGYLCTVTKECMPSCN

32

T+T ST +S+ LGN+G++CT +KECMPSCN

5

TLTTSTSIFISRGLGNDGWVCTWSKECMPSCN

36

50.0%

NZ_CP036019.1and 9 others:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27210_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27215_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27210_lanthipeptideNZ_JANIOB010000033.1 Lanthipeptides: NQ113_RS28005_lanthipeptideNZ_JH791925.1 Lanthipeptides: IE3_RS28545_lanthipeptideNZ_NUML01000015.1 Lanthipeptides: COD66_RS20150_lanthipeptideNZ_NUML01000015.1 Lanthipeptides: COD66_RS20145_lanthipeptideNZ_NUVR01000040.1 Lanthipeptides: COI88_RS26655_lanthipeptideNZ_NUVR01000040.1 Lanthipeptides: COI88_RS26650_lanthipeptide

Lanthipeptides: EXW52_RS27215_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS LGN G CT+TKECM SCN

10

LSSWLGNKGGYCTLTKECMSSCN

32

50.0%

NZ_CP042598.1and 2 others:

NZ_RKNR01000012.1 Lanthipeptides: EGW35_RS11615_lanthipeptideNZ_RKNR01000012.1 Lanthipeptides: EGW35_RS11615_lanthipeptide

Lanthipeptides: FUT28_RS13825_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS LGN G CT TKECMPSCN

12

LSDYLGNTGGWCTATKECMPSCN

34

50.0%

NZ_CP084530.1and 1 other:

NZ_CP084530.1 Lanthipeptides: LDO05_RS02075_lanthipeptide

Lanthipeptides: LDO05_RS02075_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS LGNNG CT+TKEC SCN

8

LSNYLGNNGGWCTLTKECQRSCN

30

50.0%

NZ_JADPDT010000005.1and 1 other:

NZ_JADPDT010000005.1 Lanthipeptides: I4V19_RS09885_lanthipeptide

Lanthipeptides: I4V19_RS09885_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS LGN G CT TKECMPSCN

12

LSDFLGNTGGWCTATKECMPSCN

34

50.0%

NZ_LT630004.1:

Lanthipeptides: BQ5796_RS17475_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS LGN+G CT+T ECMPSCN

2

LSSLLGNDGKFCTLTVECMPSCN

24

46.9%

NC_002570.2and 3 others:

NC_002570.2 Lanthipeptides: AYT26_RS02480_lanthipeptideNZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptideNZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptide

Lanthipeptides: AYT26_RS02480_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

+S LGN G CT+T ECMPSCN

10

ISCRLGNKGAYCTLTVECMPSCN

32

46.9%

NZ_AKXV01000031.1and 4 others:

NZ_AKXV01000031.1 Lanthipeptides: Y19_RS0109895_lanthipeptideNZ_JABBGE010000004.1 Lanthipeptides: HHL19_RS13545_lanthipeptideNZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptideNZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptide

Lanthipeptides: Y19_RS0109895_lanthipeptide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS LGN G CT+TKEC P+CN

8

LSDFLGNQGGWCTLTKECQPNCN

30

MIBiG 4.0 matches for B4090_RS08835

50.0%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

10

LSKPLGNNGYLCTVTKECMPSCN

32

LS LGNNG CT+TKEC P+CN

8

LSNALGNNGGWCTLTKECQPNCN

30

46.9%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

10

LSKPLGNNGYLCTVTKECMPSCN

32

+S LGN G CT+T ECMPSCN

6

ISCRLGNKGAYCTLTVECMPSCN

28

20.5%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

21

CTVTKECMPSCN

32

CT++KEC P+CN

28

CTLSKECQPNCN

39

allorf_433491_433559

Leader:

MLNDEMFHVNFG

Core:

AFFSCCFSAC

Core with dehydrations:

AFFDhaCysCysFDhaACys

antiSMASH-DB 4.0 matches for allorf_433491_433559

100.0%

NC_006322.1and 3 others:

NZ_CP033218.1 Lanthipeptides: allorf_1520544_1520612_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: allorf_433491_433559_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: allorf_17545_17613_lanthipeptide

Lanthipeptides: allorf_3961621_3961689_lanthipeptide

1

AFFSCCFSAC

10

AFFSCCFSAC

1

AFFSCCFSAC

10

37.5%

NZ_KB913037.1:

Lanthipeptides: A3CE_RS53890_lanthipeptide

1

AFFSCCFSAC

10

A SCC+S+C

3

ALDSCCWSSC

12

allorf_434823_434933

Leader:

MDSKYAGS

Core:

LHKIVVTLKMEVQRCKVFIRFAGNLDIF

Core with dehydrations:

LHKIVVDhbLKMEVQRCysKVFIRFAGNLDIF

antiSMASH-DB 4.0 matches for allorf_434823_434933

25.0%

NZ_AP018268.1:

Lanthipeptides: allorf_2158327_2158434_lanthipeptide

9

KMEVQRCKVF-IRFA

22

K+ V+RC V+ +RF

3

KLRVERCSVYAVRFT

17

17.9%

NZ_CP096907.1and 1 other:

NZ_KZ679047.1 Lassopeptides: C6Y14_RS25935_lassopeptide

Lassopeptides: MUK60_RS37400_lassopeptide

19

IRFAGNLDIF

28

+ F GN D+F

2

LPFGGNTDLF

11

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Transcription Factor Binding Sites

Binding sites found:

RpoN

Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 16.82 out of 18.46

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 24.91 out of 27.78

Confidence: strong

RpoN

Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 17.22 out of 18.46

Confidence: strong

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 20.99 out of 27.78

Confidence: medium

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 20.55 out of 25.88

Confidence: medium

CRP

Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 18.06 out of 19.26

Confidence: strong

CRP

Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.26 out of 19.26

Confidence: strong

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 21.90 out of 28.19

Confidence: medium

Additional weak hits (3):

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.03 out of 26.06

Confidence: weak

MntR

Description: Manganese transport regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 25.95 out of 39.62

Confidence: weak

NuR

Description: Nickel-responsive regulator
Species: Streptomyces coelicolor
Score: 22.12 out of 30.98

Confidence: weak

Lanthipeptides

TFBS Finder

Core peptide predictions

B4090_RS08830 - Class II

Cleavage pHMM score: 1.50

RODEO score: 0

Monoisotopic mass: 3632.8 Da

Molecular weight: 3635.0 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 3653.0 Da N = 1; 3671.1 Da N = 2; 3689.1 Da N = 3; 3707.1 Da N = 4; 3725.1 Da N = 5; 3743.1 Da N = 6; 3761.2 Da N = 7; 3779.2 Da N = 8; 3797.2 Da N = 9; 3815.2 Da N = 10; 3833.2 Da N = 11

B4090_RS08835 - Class II

Cleavage pHMM score: 3.30

RODEO score: 0

Monoisotopic mass: 3230.6 Da

Molecular weight: 3232.8 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 3250.8 Da N = 1; 3268.8 Da N = 2; 3286.9 Da N = 3; 3304.9 Da N = 4

B4090_RS08830 - Class II

Cleavage pHMM score: 1.50

RODEO score: 0

Monoisotopic mass: 3632.8 Da

Molecular weight: 3635.0 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 3653.0 Da N = 1; 3671.1 Da N = 2; 3689.1 Da N = 3; 3707.1 Da N = 4; 3725.1 Da N = 5; 3743.1 Da N = 6; 3761.2 Da N = 7; 3779.2 Da N = 8; 3797.2 Da N = 9; 3815.2 Da N = 10; 3833.2 Da N = 11

B4090_RS08835 - Class II

Cleavage pHMM score: 3.30

RODEO score: 0

Monoisotopic mass: 3230.6 Da

Molecular weight: 3232.8 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 3250.8 Da N = 1; 3268.8 Da N = 2; 3286.9 Da N = 3; 3304.9 Da N = 4

allorf_433491_433559 - Class II

Cleavage pHMM score: -4.30

RODEO score: 0

Monoisotopic mass: 1048.4 Da

Molecular weight: 1049.2 Da

Number of bridges: 2

allorf_434823_434933 - Class II

Cleavage pHMM score: -7.20

RODEO score: 0

Monoisotopic mass: 3298.9 Da

Molecular weight: 3301.0 Da

Number of bridges: 1

TFBS definitions

Regulator	Description
CRP	Cyclic AMP receptor protein
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
PsrA	Oleic acid responsive regulator
RpoN	Regulator of nitrogen assimilation and virulence
ZuR variant 1	Zinc-responsive repressor

NZ_LQYL01000026.1 - Region 1 - NRPS

Download region SVG

Location: 1 - 25,539 nt. (total: 25,539 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: PPTase aminotransferase

B4090_RS10135: aminotransferase

smcogs: SMCOG1019: aminotransferase

B4090_RS10140: 4'-phosphopantetheinyl transferase

smcogs: SMCOG1012: 4'-phosphopantetheinyl transferase

B4090_RS10210: aminotransferase class-III

smcogs: SMCOG1013: aminotransferase class-III

Hydrolases: esterase

B4090_RS10125: thioesterase

smcogs: SMCOG1004: thioesterase

B4090_RS10145: enterobactin/ferric enterobactin esterase

smcogs: SMCOG1098: enterobactin/ferric enterobactin esterase

Lyases: decarboxylase

B4090_RS10180: Decarboxylase, pyridoxal-dependent

smcogs: SMCOG1180: Decarboxylase, pyridoxal-dependent

Ligases: ligase

B4090_RS10115: condensation domain-containing protein

smcogs: SMCOG1127: condensation domain-containing protein

B4090_RS10120: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

Translocases: permease

B4090_RS10215: phenylalanine-specific permease

smcogs: SMCOG1038: phenylalanine-specific permease

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002075.3	0.73	NRPS	pyreudione A, pyreudione B, pyreudione C, pyreudione D, pyreudione E	Pseudomonas fluorescens
BGC0001825.4	0.68	NRPS	xenematide	Xenorhabdus nematophila AN6/1
BGC0001833.4	0.67	NRPS	icosalide A, icosalide B	Burkholderia gladioli
BGC0001132.4	0.67	NRPS	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0002286.3	0.66	NRPS	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001128.4	0.66	NRPS	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000381.5	0.66	NRPS	lichenysin	Bacillus licheniformis DSM 13 = ATCC 14580
BGC0001758.4	0.66	NRPS	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001641.4	0.65	NRPS	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001135.5	0.64	NRPS	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002075.3	0.73	NRPS	pyreudione A, pyreudione B, pyreudione C, pyreudione D, pyreudione E	Pseudomonas fluorescens
BGC0001825.4	0.68	NRPS	xenematide	Xenorhabdus nematophila AN6/1
BGC0001833.4	0.67	NRPS	icosalide A, icosalide B	Burkholderia gladioli
BGC0001132.4	0.67	NRPS	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0002286.3	0.66	NRPS	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001128.4	0.66	NRPS	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000381.5	0.66	NRPS	lichenysin	Bacillus licheniformis DSM 13 = ATCC 14580
BGC0001758.4	0.66	NRPS	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001641.4	0.65	NRPS	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001135.5	0.64	NRPS	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 24.36 out of 27.78

Confidence: strong

RpoN

Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 17.31 out of 18.46

Confidence: strong

CcpA

Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 18.67 out of 20.97

Confidence: medium

CcpA

Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 18.40 out of 20.97

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.67 out of 27.78

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 21.70 out of 27.78

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 21.26 out of 28.19

Confidence: medium

Additional weak hits (4):

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 20.31 out of 26.06

Confidence: weak

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 23.87 out of 32.74

Confidence: weak

ArcA

Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 18.15 out of 21.55

Confidence: weak

NuR

Description: Nickel-responsive regulator
Species: Streptomyces coelicolor
Score: 22.47 out of 30.98

Confidence: weak

Module view

Legend

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS substrates

TFBS Finder

Predicted core structure(s)

For candidate cluster 1, location 0 - 25539:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Ile)

Direct lookup in NORINE database: strict or relaxed

NRPS/PKS substrate predictions

B4090_RS10120: Ile

Search NORINE for peptide: strict or relaxed

AMP-binding (472..870): Ile

nrpys: Ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: ile (Ile)

Stachelhaus prediction details:

Stachelhaus sequence:: VETSFDGFTFDGFVLFGGEIHVYGPTETTVFATF
Nearest Stachelhaus code(s):: Ile DGFFLGVVFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

TFBS definitions

Regulator	Description
CcpA	Catabolite control protein A
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
RpoN	Regulator of nitrogen assimilation and virulence
ZuR variant 1	Zinc-responsive repressor

NZ_LQYL01000030.1 - Region 1 - betalactone

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Location: 576,137 - 604,651 nt. (total: 28,515 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

B4090_RS14830: acyl-CoA dehydrogenase

smcogs: SMCOG1006: acyl-CoA dehydrogenase

Transferases: carboxylase transferase

B4090_RS14800: acetyl-CoA carboxylase, carboxyl transferase,

smcogs: SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,

B4090_RS14820: acetyl-CoA carboxylase biotin carboxylase

smcogs: SMCOG1090: acetyl-CoA carboxylase biotin carboxylase

Lyases: hydratase

B4090_RS14805: enoyl-CoA hydratase

smcogs: SMCOG1023: enoyl-CoA hydratase

Ligases: ligase synthase

B4090_RS14795: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

B4090_RS14810: 2-isopropylmalate synthase

smcogs: SMCOG1271: 2-isopropylmalate synthase

B4090_RS14825: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001249.5	0.56	NRPS	dimethylcoprogen	Alternaria alternata
BGC0001268.4	0.54	NRPS, PKS	fusarin C	Fusarium fujikuroi
BGC0002284.3	0.53	other (other)	corynecin III, corynecin I, corynecin II	Rhodococcus sp. H-CA8f
BGC0001160.5	0.52	PKS	1-nonadecene, (14Z)-1,14-nonadecadiene	Synechococcus sp. PCC 7002
BGC0001164.3	0.51	PKS	1-heptadecene	Cyanothece sp. PCC 7822
BGC0001103.5	0.49	NRPS, PKS	mycosubtilin	Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001095.5	0.46	NRPS	fengycin	Bacillus velezensis FZB42
BGC0002405.2	0.45	saccharide	mid-chain acyl sugars	Solanum lycopersicum
BGC0000706.3	0.45	saccharide	kanamycin	Streptomyces kanamyceticus
BGC0001077.4	0.45	PKS	6-anteisoheptadecyl-4-O-dihydrogeranyl-2-methoxyhydroquinone, 6-isoheptadecyl-4-O-dihydrogeranyl-2-methoxyhydroquinone, 6-isopalmityl-4-O-geranyl-2-methoxyhydroquinone, 6-palmityl-4-O-geranyl-2-methoxyhydroquinone, 6-anteisoheptadecyl-4-O-geranyl-2-methoxyhydroquinone, 6-isoheptadecyl-4-O-geranyl-2-methoxyhydroquinone, 6-isopalmityl-4-O-dihydrofarnesyl-2-methoxyhydroquinone, 6-palmityl-4-O-dihydrofarnesyl-2-methoxyhydroquinone, 6-anteisoheptadecyl-4-O-dihydrofarnesyl-2-methoxyhydroquinone, 6-isoheptadecyl-4-O-dihydrofarnesyl-2-methoxyhydroquinone	Actinoplanes missouriensis 431

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001249.5	0.56	NRPS	dimethylcoprogen	Alternaria alternata
BGC0001268.4	0.54	NRPS, PKS	fusarin C	Fusarium fujikuroi
BGC0002284.3	0.53	other (other)	corynecin III, corynecin I, corynecin II	Rhodococcus sp. H-CA8f
BGC0001160.5	0.52	PKS	1-nonadecene, (14Z)-1,14-nonadecadiene	Synechococcus sp. PCC 7002
BGC0001164.3	0.51	PKS	1-heptadecene	Cyanothece sp. PCC 7822
BGC0001103.5	0.49	NRPS, PKS	mycosubtilin	Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001095.5	0.46	NRPS	fengycin	Bacillus velezensis FZB42
BGC0002405.2	0.45	saccharide	mid-chain acyl sugars	Solanum lycopersicum
BGC0000706.3	0.45	saccharide	kanamycin	Streptomyces kanamyceticus
BGC0001077.4	0.45	PKS	6-anteisoheptadecyl-4-O-dihydrogeranyl-2-methoxyhydroquinone, 6-isoheptadecyl-4-O-dihydrogeranyl-2-methoxyhydroquinone, 6-isopalmityl-4-O-geranyl-2-methoxyhydroquinone, 6-palmityl-4-O-geranyl-2-methoxyhydroquinone, 6-anteisoheptadecyl-4-O-geranyl-2-methoxyhydroquinone, 6-isoheptadecyl-4-O-geranyl-2-methoxyhydroquinone, 6-isopalmityl-4-O-dihydrofarnesyl-2-methoxyhydroquinone, 6-palmityl-4-O-dihydrofarnesyl-2-methoxyhydroquinone, 6-anteisoheptadecyl-4-O-dihydrofarnesyl-2-methoxyhydroquinone, 6-isoheptadecyl-4-O-dihydrofarnesyl-2-methoxyhydroquinone	Actinoplanes missouriensis 431

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57

Confidence: strong

CcpA

Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 19.78 out of 20.97

Confidence: strong

RpoN

Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 18.15 out of 18.46

Confidence: strong

AfsQ1

Description: Two-component system AfsQ1-Q2, activator of antibiotic production
Species: Streptomyces coelicolor
Score: 17.23 out of 19.52

Confidence: medium

Additional weak hits (6):

MntR

Description: Manganese transport regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 24.85 out of 39.62

Confidence: weak

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 21.72 out of 29.25

Confidence: weak

ClgR

Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 21.03 out of 30.22

Confidence: weak

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 22.84 out of 29.65

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.50 out of 26.06

Confidence: weak

NrtR

Description: NAD synthesis repressor
Species: Streptomyces coelicolor
Score: 22.73 out of 35.63

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
AfsQ1	Two-component system AfsQ1-Q2, activator of antibiotic production
CcpA	Catabolite control protein A
RpoN	Regulator of nitrogen assimilation and virulence
ToxT	Regulator of MSHA biosynthesis

NZ_LQYL01000030.1 - Region 2 - terpene

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Location: 701,049 - 722,938 nt. (total: 21,890 nt) Show pHMM detection rules used

terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

B4090_RS15375: aldehyde dehydrogenase

smcogs: SMCOG1017: aldehyde dehydrogenase

Transferases: acetyltransferase

B4090_RS15385: GCN5-related N-acetyltransferase

smcogs: SMCOG1111: GCN5-related N-acetyltransferase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001535.3	0.42	other (other)	branched-chain fatty acids	Streptomyces filamentosus
BGC0002449.2	0.38	other (other)	sarasinoside	uncultured bacterium
BGC0002006.2	0.36	ribosomal	albusnodin	Streptomyces albus
BGC0000313.4	0.36	NRPS	beauvericin	Beauveria bassiana
BGC0002255.3	0.33	PKS	lijiquinone	Ascomycota sp. F53
BGC0001575.4	0.32	NRPS	PZN5, PZN6, PZN7, PZN9, PZN10, PZN11	Ruminococcus sp. 5_1_39BFAA
BGC0001338.4	0.31	PKS	citrinin	Monascus ruber
BGC0000154.4	0.31	PKS	stipitatic acid	Talaromyces stipitatus ATCC 10500
BGC0001739.3	0.30	other (other)	phosphonoacetic Acid	Streptomyces sp. NRRL F-525
BGC0000663.5	0.30	terpene	hopene	Streptomyces coelicolor A3(2)

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001535.3	0.42	other (other)	branched-chain fatty acids	Streptomyces filamentosus
BGC0002449.2	0.38	other (other)	sarasinoside	uncultured bacterium
BGC0002006.2	0.36	ribosomal	albusnodin	Streptomyces albus
BGC0000313.4	0.36	NRPS	beauvericin	Beauveria bassiana
BGC0002255.3	0.33	PKS	lijiquinone	Ascomycota sp. F53
BGC0001575.4	0.32	NRPS	PZN5, PZN6, PZN7, PZN9, PZN10, PZN11	Ruminococcus sp. 5_1_39BFAA
BGC0001338.4	0.31	PKS	citrinin	Monascus ruber
BGC0000154.4	0.31	PKS	stipitatic acid	Talaromyces stipitatus ATCC 10500
BGC0001739.3	0.30	other (other)	phosphonoacetic Acid	Streptomyces sp. NRRL F-525
BGC0000663.5	0.30	terpene	hopene	Streptomyces coelicolor A3(2)

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
triterpene	hopanoid		C30	hopanoid skeleton	unknown
triterpene	polypodane		C30	polypodane skeleton	unknown

Genes with terpene domains:

B4090_RS15395: T2TS

Domain 1 (5 - 625): Type 2 terpene synthase

Subtype: Squalene substrate

Reactions:: squalene → hopanoid; squalene → polypodane

Transcription Factor Binding Sites

Binding sites found:

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.31 out of 18.57

Confidence: strong

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 22.17 out of 25.88

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.10 out of 27.78

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 23.26 out of 27.78

Confidence: medium

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 24.20 out of 30.25

Confidence: medium

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 24.33 out of 29.65

Confidence: medium

Additional weak hits (2):

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.52 out of 26.06

Confidence: weak

HexR

Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 23.21 out of 31.73

Confidence: weak

Terpene

TFBS Finder

Glossary

No acronyms to display

TFBS definitions

Regulator	Description
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
ColR	Phenol-responsive regulator
LexA variant 1	Repressor of DNA damage response
PsrA	Oleic acid responsive regulator
ToxT	Regulator of MSHA biosynthesis

NZ_LQYL01000030.1 - Region 3 - T3PKS

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Location: 772,305 - 813,402 nt. (total: 41,098 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: acetyltransferase methyltransferase

B4090_RS15835: isoprenylcysteine carboxyl methyltransferase

smcogs: SMCOG1150: isoprenylcysteine carboxyl methyltransferase

B4090_RS15845: GCN5-related N-acetyltransferase

smcogs: SMCOG1111: GCN5-related N-acetyltransferase

Ligases: synthase

B4090_RS15840: chalcone and stilbene synthase domain protein

smcogs: SMCOG1024: chalcone and stilbene synthase domain protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000282.3	0.69	PKS	2-methoxy-5-methyl-6-(13-methyltetradecyl)-1,4-benzoquinone, 2-methoxy-5-methyl-6-(13-methyltetradecyl)phenol	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001831.3	0.51	PKS	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001475.4	0.42	terpene	aspterric acid	Aspergillus terreus NIH2624
BGC0001647.3	0.39	PKS	lagunapyrone A, lagunapyrone B, lagunapyrone C	Streptomyces sp. MP131-18
BGC0001289.5	0.35	ribosomal	penisin	Paenibacillus ehimensis
BGC0001928.2	0.32	other (other)	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0001964.2	0.32	PKS	alkylpyrone-407, alkylpyrone-393	Cystobacterineae bacterium
BGC0002254.3	0.31	PKS	notoamide F, (+)-semivioxanthin, waikikiamide B, waikikiamide C, notoamide A, waikikiamide A	Aspergillus sp. FM242
BGC0001663.3	0.30	PKS	merocyclophane C, merocyclophane D	Nostoc sp. UIC 10110
BGC0002432.2	0.28	NRPS	laterocidine	Brevibacillus laterosporus LMG 15441

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000282.3	0.69	PKS	2-methoxy-5-methyl-6-(13-methyltetradecyl)-1,4-benzoquinone, 2-methoxy-5-methyl-6-(13-methyltetradecyl)phenol	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001831.3	0.51	PKS	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001475.4	0.42	terpene	aspterric acid	Aspergillus terreus NIH2624
BGC0001647.3	0.39	PKS	lagunapyrone A, lagunapyrone B, lagunapyrone C	Streptomyces sp. MP131-18
BGC0001289.5	0.35	ribosomal	penisin	Paenibacillus ehimensis
BGC0001928.2	0.32	other (other)	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0001964.2	0.32	PKS	alkylpyrone-407, alkylpyrone-393	Cystobacterineae bacterium
BGC0002254.3	0.31	PKS	notoamide F, (+)-semivioxanthin, waikikiamide B, waikikiamide C, notoamide A, waikikiamide A	Aspergillus sp. FM242
BGC0001663.3	0.30	PKS	merocyclophane C, merocyclophane D	Nostoc sp. UIC 10110
BGC0002432.2	0.28	NRPS	laterocidine	Brevibacillus laterosporus LMG 15441

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 21.53 out of 27.78

Confidence: medium

CRP

Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 18.06 out of 19.26

Confidence: strong

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.31 out of 18.57

Confidence: strong

CcpA

Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 19.87 out of 20.97

Confidence: strong

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 27.81 out of 29.38

Confidence: strong

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 24.26 out of 29.38

Confidence: medium

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 25.54 out of 29.38

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 20.91 out of 27.78

Confidence: medium

MexT

Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 18.58 out of 21.84

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 21.55 out of 27.78

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.99 out of 26.06

Confidence: medium

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 20.32 out of 23.79

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 26.44 out of 28.19

Confidence: strong

LexA variant 3

Description: Repressor of DNA damage response
Species: Escherichia coli str. K-12 substr. MG1655
Score: 25.03 out of 32.93

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.57 out of 28.19

Confidence: medium

Additional weak hits (25):

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.19 out of 26.06

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.15 out of 26.06

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 21.28 out of 28.14

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 20.59 out of 26.06

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.49 out of 26.06

Confidence: weak

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 24.10 out of 32.74

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 22.19 out of 29.38

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 21.98 out of 28.14

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 21.98 out of 28.14

Confidence: weak

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 23.61 out of 32.74

Confidence: weak

NtrC

Description: Nitrogen regulatory protein C
Species: Pseudomonas putida KT2440
Score: 21.38 out of 29.72

Confidence: weak

CopR

Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 21.66 out of 30.97

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.48 out of 26.06

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.47 out of 26.06

Confidence: weak

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 20.57 out of 26.06

Confidence: weak

CopR

Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 23.13 out of 30.97

Confidence: weak

ZuR variant 2

Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 24.16 out of 33.14

Confidence: weak

NrtR

Description: NAD synthesis repressor
Species: Streptomyces coelicolor
Score: 23.94 out of 35.63

Confidence: weak

LexA variant 3

Description: Repressor of DNA damage response
Species: Escherichia coli str. K-12 substr. MG1655
Score: 23.21 out of 32.93

Confidence: weak

NrtR

Description: NAD synthesis repressor
Species: Streptomyces coelicolor
Score: 24.02 out of 35.63

Confidence: weak

ZuR variant 2

Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 22.25 out of 33.14

Confidence: weak

HypR

Description: L-hydroxyproline utilization repressor
Species: Streptomyces coelicolor
Score: 18.94 out of 22.40

Confidence: weak

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 20.98 out of 29.65

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 21.28 out of 28.14

Confidence: weak

ZuR variant 2

Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 22.63 out of 33.14

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
CRP	Cyclic AMP receptor protein
CcpA	Catabolite control protein A
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
FuR variant 1	Ferric Uptake Regulator
IolR	Regulator of the inositol catabolism
LexA variant 3	Repressor of DNA damage response
MexT	Global virulence regulator
MogR	Repressor of flagellar motility genes
ToxT	Regulator of MSHA biosynthesis
ZuR variant 1	Zinc-responsive repressor

NZ_LQYL01000030.1 - Region 4 - terpene-precursor