LOCUS       NZ_LQYL01000030        28515 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Bacillus licheniformis strain B4090_201601 NODE_80, whole genome
            shotgun sequence.
ACCESSION   NZ_LQYL01000030
VERSION     NZ_LQYL01000030.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus licheniformis
  ORGANISM  Bacillus licheniformis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 1653177)
  AUTHORS   Krawczyk,A.O., de Jong,A., Holsappel,S., Eijlander,R.T., van
            Heel,A., Berendsen,E.M., Wells-Bennik,M.H. and Kuipers,O.P.
  TITLE     Genome Sequences of 12 Spore-Forming Bacillus Species, Comprising
            Bacillus coagulans, Bacillus licheniformis, Bacillus
            amyloliquefaciens, Bacillus sporothermodurans, and Bacillus
            vallismortis, Isolated from Foods
  JOURNAL   Genome Announc 4 (3), e00103-16 (2016)
   PUBMED   27174261
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1653177)
  AUTHORS   Berendsen,E.M., Wells-Bennik,M.H., Krawcyk,A.O., De Jong,A.,
            Holsappel,S., Eijlander,R.T. and Kuipers,O.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JAN-2016) Molecular Genetics, University of Groningen,
            Nijenborgh 7, Groningen, Groningen 9747AG, the Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2015
            Assembly Method                   :: Velvet v. 1.2.10
            Assembly Name                     :: B4090
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/26/2024 01:23:23
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,545
            CDSs (total)                      :: 4,463
            Genes (coding)                    :: 4,342
            CDSs (with protein)               :: 4,342
            Genes (RNA)                       :: 82
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 121
            CDSs (without protein)            :: 121
            Pseudo Genes (ambiguous residues) :: 0 of 121
            Pseudo Genes (frameshifted)       :: 68 of 121
            Pseudo Genes (incomplete)         :: 58 of 121
            Pseudo Genes (internal stop)      :: 20 of 121
            Pseudo Genes (multiple problems)  :: 22 of 121
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:24:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 576136
            Orig. end                         :: 604651
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LQYL01000030.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..28515
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..28515
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28515
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:18515](-)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..18515)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     misc_feature    381..401
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 24.85"
                     /tool="antismash"
     misc_feature    complement(411..426)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.23"
                     /tool="antismash"
     gene            complement(554..1006)
                     /locus_tag="B4090_RS14735"
                     /old_locus_tag="B4090_2281"
     CDS             complement(554..1006)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226102.1"
                     /locus_tag="B4090_RS14735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2281"
                     /product="hypothetical protein"
                     /protein_id="WP_060965122.1"
                     /transl_table=11
                     /translation="MVALFLLLTLTGCWSRYEVQNMNYATAVGIDYVDGQYTMYLQLLD
                     FSTVAKLEGQQKAEQPPVWVGKGEGSSFTEAANDLYSTSQQRLNLGQISAILFSERLMK
                     ENKVGEVLELINRYREIRYLAWLFSTREPPEEILLATPFFRFSPNA"
     gene            complement(1021..2055)
                     /locus_tag="B4090_RS14740"
                     /old_locus_tag="B4090_2282"
     CDS             complement(1021..2055)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0009847 - spore germination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002037536.1"
                     /locus_tag="B4090_RS14740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2282"
                     /product="spore germination protein"
                     /protein_id="WP_231120556.1"
                     /transl_table=11
                     /translation="MEEVGVNVALIRKRIKSTSMVYETKKVGVRTKTTVAILYMRDIVD
                     PKIVQDVKNKLDDLHIDGAFSATQLEELMEPTKALFPLMGYTGRADFTVNCMLNGRVAL
                     IVDGTPAALIAPANLFLLVKAPEDIHFTALAATFGQTLRLLGLSVSLLLPAFFVAILSY
                     HQDQLPYYLLATLGINRLGIPFDVAVEMFIALLFLEILREAGIRLPSAVGSTVTVVGGL
                     ILGDAAIRAGFLSPGIVVIGAITQIFGSTLSSLSLAGTISTLRFFLFILSATLGIYGFF
                     LGLFIVLSHLASLRSCGLPYLAPISPPFKDLANALFRLPWPWRNTRPDMLKTRDSTRQG
                     DRHK"
     gene            complement(1988..2290)
                     /locus_tag="B4090_RS14745"
     CDS             complement(1988..2290)
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017697717.1"
                     /locus_tag="B4090_RS14745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_061576743.1"
                     /transl_table=11
                     /translation="MFKLYLDPGHGRMDPVAIGNGMQEKEITLNISHSIRNLLENHYEG
                     LQIKMSRTADITRSLKERTDDANAFGTGAKGWICGRSGSQCGVNSETNQINQHGL"
     gene            2652..3104
                     /locus_tag="B4090_RS14750"
     CDS             2652..3104
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701229.1"
                     /locus_tag="B4090_RS14750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_045514182.1"
                     /transl_table=11
                     /translation="MKIPNTAKVSIPFPSVWGIDASIAGRSIIRGILTIDSIVDNKVVG
                     TVNFRGIPIPINGYWDESAKQISFDSPYASFFGNLTIIDETAISIRHFILSGRFIMKPP
                     SLLAGEYGNWIATTFTTRLGPPIYTNVLPPVGAFSVSSMLLGQQLF"
     gene            complement(3354..>3563)
                     /locus_tag="B4090_RS14755"
                     /old_locus_tag="B4090_2283"
                     /pseudo=""
     CDS             complement(3354..>3563)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001169292.1"
                     /locus_tag="B4090_RS14755"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2283"
                     /product="helix-turn-helix domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="LQMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKLYKEGNMT
                     VNQICEITNVSRASLYRKLSEGKK"
     gene            3527..6460
                     /locus_tag="B4090_RS14760"
                     /old_locus_tag="B4090_2284"
     CDS             3527..6460
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844996.1"
                     /locus_tag="B4090_RS14760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2284"
                     /product="Tn3 family transposase"
                     /protein_id="WP_061576744.1"
                     /transl_table=11
                     /translation="MRAQFLHADASEDEWILGTYFTFSKRDLEIVNKRRREENRLGFAV
                     QLAVLRYPGWPYTHIKSIPESVIHYISKQIGATPSSISLYPQRENTLWDHLKELRSEYD
                     FVTFTLREYRIAFKHLHQLAFENGDAIHLLHECIDFLRKNKIILPAITTLERMVWEARA
                     MAEKKLFNTVSQSLTNEQKGKLEEIITSQHPSESNKTILGWLKEPPGHPSPETFLKVIE
                     RLEYIRGMELETVQISHLHRNRLFQLSRLGSRYEPYAFRDFQENKRYSILTVYLLHLTQ
                     ELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIHFTNIGQALIKAKKEKLD
                     VFEVLESVIEWNSFVSSVEEAQELARPDDYDYLDLLQKRFYSLRKYTPTLLRVLEFHST
                     KANEPLLQAVEIIRGMNESGKRKVPDNSPVDFISKRWKKHLYEDDGTTINRHYYEMAVL
                     TELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQTKENTRLSVSLSFEDYMTERTSSL
                     NKRLKWLATNSNKLDGVSLEKGKLSIERLEKDVPEEAKKFSASLYQMLPRIKLTDLLMD
                     IAYITGFHEQFIHASNNRKPDKEETIIIMAALLGMGMNIGLSKMAEATPGLTYKQLANV
                     SQWRMYEDAMNKAQAVLVNFHHKLQLSSYWGDGTTSSSDGMRMQIGVSSLHADANPHYG
                     TGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLDGLLHHETDLNIVEHYTDTAGYTDQ
                     IFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYPKLEVILRGQINTKVIKENYEDVLRL
                     AHSIREGTVSASLIMGKLGSYSRQNSLATALREMGRIEKTIFILNYISDESLRRKIQKG
                     LNKGEAMNGLARAIFFGKQGELRERTIQHQLQRASALNIIINAISIWNTLHLTKAVEYQ
                     KRSGSFNEELLHHMSPLGWEHINLLGEYHFNSEKMVSLDSLRPLKLS"
     gene            complement(6437..7222)
                     /locus_tag="B4090_RS14765"
                     /old_locus_tag="B4090_2285"
     CDS             complement(6437..7222)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B4090_RS14765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B4090_2285"
                     /product="ABC transporter permease"
                     /protein_id="WP_235598197.1"
                     /transl_table=11
                     /translation="MNQNILTRTESQLAFYGLAPFLLIIVTAAGVPLSAELTEFNITPY
                     RHLIMSLAMLFIPLILGVMSGFILLDERDENMIQYFAVTPLSKRGYVMIRLILPMAMTL
                     CYSILLFASGGLMAPGAVNLLFVLIMVTLEAPIYTLLLAAYVANKVEGLALMKGFSLLT
                     LMPAAVYFIPVPWQLFGVFTLLDSENVLGGNIPRRAFSRFRDHRNCAAHYDTAVFIPEV
                     FGENRPIGGTVRKMRIYNAKPISPTIPPVLTTLRKFQGS"
     gene            complement(7313..8491)
                     /locus_tag="B4090_RS14770"
                     /old_locus_tag="B4090_2286"
     CDS             complement(7313..8491)
                     /EC_number="1.6.5.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389111.1"
                     /locus_tag="B4090_RS14770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2286"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_003182436.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 5.4e-45, bitscore:
                     150.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKHIVILGAGYGGLLSALTVRKHYTKEEAKVTVVNQYPTHQIIT
                     ELHRLAAGNVSEQAVAMPLAKLFKGKDIDLKIAKVNSFSVDKKEVALSDGSTLTYDALV
                     VGLGSVTAYFGIPGLEENSMVLKSANDANKIFKHVEERVREYAKTKNEADATILIGGGG
                     LTGVELVGELADIMPSLARSYGVDPTEIKLKLVEAGPKILPVLPDELIERATKSLEKRG
                     VEFLTGLPVTNVEGNVVDLKDGQKIVTNTFVWTGGVQGNPLIGESGLEVNRGRATVNDF
                     LQSTSHEDVFVAGDSAVVFGPDGRPYPPTAQIAWQMGELIGYNLYAYLENKSMATFSPV
                     NSGTLASLGRKDAVAVIGANSTSLKGLPASLMKEASNVRYLSHIKGLFSLAY"
     gene            complement(8528..8962)
                     /locus_tag="B4090_RS14775"
                     /old_locus_tag="B4090_2287"
     CDS             complement(8528..8962)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389110.1"
                     /locus_tag="B4090_RS14775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2287"
                     /product="DUF1641 domain-containing protein"
                     /protein_id="WP_003182438.1"
                     /transl_table=11
                     /translation="MPETIDQTADQTNESVSQSQRDLIDQLLKPEVQESLTVLVDQLPK
                     LTELVNILTKSYDFAQSVATDEVLKNDTVGAITEILEPVKDTAKEIAATAIEAKDRADE
                     SNEVIGLFGLLKMLKDPQAQKLFRFVQSYLQIMSEREKQK"
     misc_feature    8994..9003
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            complement(9372..9602)
                     /locus_tag="B4090_RS14785"
                     /old_locus_tag="B4090_2289"
     CDS             complement(9372..9602)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276022.1"
                     /locus_tag="B4090_RS14785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2289"
                     /product="excisionase family DNA-binding protein"
                     /protein_id="WP_003182442.1"
                     /transl_table=11
                     /translation="MYLTIKETAEYLTLSEAYVEQLVREKKIRTVFDGQQHLINKEQFN
                     THMEQMEKYKEWAESVLNEPIPEDPDVKDED"
     gene            9695..9919
                     /locus_tag="B4090_RS14790"
                     /old_locus_tag="B4090_2290"
     CDS             9695..9919
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B4090_RS14790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B4090_2290"
                     /product="hypothetical protein"
                     /protein_id="WP_003182444.1"
                     /transl_table=11
                     /translation="MYSKWNSETSYPPSAPQMHTGQSSQQMNQRLKNLEDQMELLIKLM
                     ESNNQLLRSIEEQQNRVCTAGGGSVIVRM"
     gene            complement(10001..11953)
                     /locus_tag="B4090_RS14795"
                     /old_locus_tag="B4090_2291"
     CDS             complement(10001..11953)
                     /NRPS_PKS="Domain: AMP-binding (97-523). E-value: 3.1e-88.
                     Score: 288.0. Matches aSDomain:
                     nrpspksdomains_B4090_RS14795_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003182446.1"
                     /locus_tag="B4090_RS14795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2291"
                     /product="AMP-binding protein"
                     /protein_id="WP_061576746.1"
                     /sec_met_domain="AMP-binding (E-value: 2.2e-97, bitscore:
                     322.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEKAVWQPDPEFVKTTRLFQWMTALGFSDYDDFLKASTNDIAWF
                     WEEAEKALGITWYKRYSQTLNLDKGIKWPQWFTGGRLNAVYNAVEKWARRPDTAGRTAL
                     IWESEDGKTEQITYSSLHQQVARAAAGFKKQGISKGDVIAIYMPMIPETVIAMLAAAKI
                     GAVFSPVFSGYGAHAAAARLTAAGAKILVTADAFLRRGKKVCMKKEADKAADRSPTVQK
                     VVVCKLHGGDQDWNYKRDIDWNELMKNEPMQNTEEMDSSDPLMLLYTSGTTGQPKGAVH
                     THAGFPLKAAFDAGFGMDVKQGDTFFWFTDMGWMMGPFLIFGGLINGAAVLLFDGAPDY
                     PAPDRLWELVSRHRVTHLGVSPTLIRSLMQHGEDFLYQYNLNSLKAIGSTGEPWNYEPW
                     MWLFRHVGKERIPIFNYSGGTEISGGILGNVLLRPITPMTFNSPLPGMAANVFNEKGEE
                     VVNEVGELVLTKPWVGMTNGFWKEPSRYEEAYWSRWTDVWVHGDWAKRDENGYWTISGR
                     SDDVINAAGKRIGPAEIESVLVGHPAVAEAGVIGVPDKLKGQAAVCFVVLRQSEKPSEE
                     LKDDLLNLASDAIGKAVKPKAVYFVSGLPKTRNAKVMRRLIRAAYMNEPAGDLSTLENR
                     ETYDEIAGLSVRKNL"
     CDS_motif       complement(10349..10408)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS14795_0002"
                     /evalue="4.50E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="B4090_RS14795"
                     /protein_end="535"
                     /protein_start="515"
                     /score="13.0"
                     /tool="antismash"
                     /translation="GRSDDVINAAGKRIGPAEIE"
     aSDomain        complement(10385..11662)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B4090_RS14795_AMP-binding.1"
                     /evalue="3.10E-88"
                     /label="B4090_RS14795_AMP-binding.1"
                     /locus_tag="B4090_RS14795"
                     /protein_end="523"
                     /protein_start="97"
                     /score="288.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="TAGRTALIWESEDGKTEQITYSSLHQQVARAAAGFKKQGISKGDV
                     IAIYMPMIPETVIAMLAAAKIGAVFSPVFSGYGAHAAAARLTAAGAKILVTADAFLRRG
                     KKVCMKKEADKAADRSPTVQKVVVCKLHGGDQDWNYKRDIDWNELMKNEPMQNTEEMDS
                     SDPLMLLYTSGTTGQPKGAVHTHAGFPLKAAFDAGFGMDVKQGDTFFWFTDMGWMMGPF
                     LIFGGLINGAAVLLFDGAPDYPAPDRLWELVSRHRVTHLGVSPTLIRSLMQHGEDFLYQ
                     YNLNSLKAIGSTGEPWNYEPWMWLFRHVGKERIPIFNYSGGTEISGGILGNVLLRPITP
                     MTFNSPLPGMAANVFNEKGEEVVNEVGELVLTKPWVGMTNGFWKEPSRYEEAYWSRWTD
                     VWVHGDWAKRDENGYWTISGRSDDVIN"
     CDS_motif       complement(11105..11161)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS14795_0001"
                     /evalue="3.20E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="B4090_RS14795"
                     /protein_end="283"
                     /protein_start="264"
                     /score="22.8"
                     /tool="antismash"
                     /translation="MLLYTSGTTGQPKGAVHTH"
     gene            complement(11984..13513)
                     /locus_tag="B4090_RS14800"
                     /old_locus_tag="B4090_2292"
     CDS             complement(11984..13513)
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003220176.1"
                     /locus_tag="B4090_RS14800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2292"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_003182447.1"
                     /transl_table=11
                     /translation="MPAEKELYERIRRIQEGGAEKYHEANKKKGKLFVRDRLKLLLDEG
                     LDLEDAFFANCMADGLPADGVVTGIGKIGGRTVCVMANDSTVKAGSWGARTVEKIIRIQ
                     ETAEKLNCPLLYLVDSAGARITDQVDMFPGRRGAGRIFYQQVKLSGRIPQICLLFGPSA
                     AGGAYIPAFCDIVIMVEGNASMYLGSPRMAEMVIGEKVSLEEMGGARMHCSVSGCGDIL
                     ADTEEDAIKSARRYLSYFPSNYTEKAPVIEAKSARPFDRSLEDIIPKNQNAPFQMMDLI
                     DRIIDEASFYEIKKLFAPELITGLARIHGQPVGIIANQPRVKGGVLFHDSADKAAKFIN
                     LCDAYHIPLLFLADIPGFMIGTKVERAGIIRHGAKMISAMAEATVPKISVIVRKAYGAG
                     LYAMAGPAFEPDCCLALPTAQIAVMGPEAAVNAVYAKKIAELPEEERSAFIAEKRKEYQ
                     KDIDIYRLASEMIVDGIIPADSLRTELIKRLNAYMTKYMTFTERKHPVYPV"
     gene            complement(13534..14316)
                     /locus_tag="B4090_RS14805"
                     /old_locus_tag="B4090_2293"
     CDS             complement(13534..14316)
                     /EC_number="4.2.1.17"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (10-252). E-value: 2.9e-72. Score:
                     234.8. Matches aSDomain:
                     nrpspksdomains_B4090_RS14805_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003182449.1"
                     /locus_tag="B4090_RS14805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2293"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_003182449.1"
                     /transl_table=11
                     /translation="MEPNVLYSINEQSVAVLTLNRPQAANALSLGLLDDFQRILRDIRS
                     NPAVRCVIITGKGDRTFCAGADLKERARMSQTEAKQAVSLIQRVVSETEKLPQPVIASL
                     NGSALGGGLELALACDIRIAAEHIELGLPETTLAIIPGAGGTQRLPRLIGRGKAKEMIF
                     TGCRISAEEAQKISLVEHVVPLSKLKEASESIAANIAANGPVAVRQAKFAINQGLETAI
                     ETGLAIEQKAYELTIPTKDRTEGLKAFAEKRKPDYTGE"
     aSDomain        complement(13561..14286)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B4090_RS14805_ECH.1"
                     /evalue="2.90E-72"
                     /label="B4090_RS14805_ECH.1"
                     /locus_tag="B4090_RS14805"
                     /protein_end="252"
                     /protein_start="10"
                     /score="234.8"
                     /tool="antismash"
                     /translation="EQSVAVLTLNRPQAANALSLGLLDDFQRILRDIRSNPAVRCVIIT
                     GKGDRTFCAGADLKERARMSQTEAKQAVSLIQRVVSETEKLPQPVIASLNGSALGGGLE
                     LALACDIRIAAEHIELGLPETTLAIIPGAGGTQRLPRLIGRGKAKEMIFTGCRISAEEA
                     QKISLVEHVVPLSKLKEASESIAANIAANGPVAVRQAKFAINQGLETAIETGLAIEQKA
                     YELTIPTKDRTEGLKAFAEK"
     gene            complement(14336..15247)
                     /locus_tag="B4090_RS14810"
                     /old_locus_tag="B4090_2294"
     CDS             complement(14336..15247)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003182451.1"
                     /locus_tag="B4090_RS14810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2294"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_009328129.1"
                     /sec_met_domain="HMGL-like (E-value: 1.4e-53, bitscore:
                     178.9, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVPKNIFIKEVGPRDGLQNEQTALSTADKITWIDMLSATGLSYI
                     EITSFVHPKWIPALSDALDVAKGINRKPGVTYAALIPNRKGLERALEGGIDEASVFMSA
                     SETHNRKNINKSIGETLPVLKEVIGAAKQASLTARAYLSTVFGCPYEHHVPLEQIIRTS
                     ETLFDMGINELSLGDTIGAANPVQVQRVLEVLLKRFPKENIALHFHDTRGMALANMIAA
                     MDMGITVFDSSCGGLGGCPYAPGATGNAATDDLIYMCAQMGIETGVDLSKLLSAAKWIE
                     DKTGRELPSRNLQAAKSKNCFH"
     gene            complement(15265..15477)
                     /locus_tag="B4090_RS14815"
                     /old_locus_tag="B4090_2295"
     CDS             complement(15265..15477)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006637155.1"
                     /locus_tag="B4090_RS14815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2295"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="WP_003182452.1"
                     /transl_table=11
                     /translation="MNTVVTNMAGNVWKILVKAGDKIEKGQEVAILESMKMEIPIVAET
                     AGTVKTVRKNEGDFADEGDVLLELQ"
     gene            complement(15495..16835)
                     /locus_tag="B4090_RS14820"
                     /old_locus_tag="B4090_2296"
     CDS             complement(15495..16835)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003182454.1"
                     /locus_tag="B4090_RS14820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2296"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_003182454.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 8.2e-14,
                     bitscore: 48.3, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 1.7e-09, bitscore:
                     34.2, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKKVLIANRGEIALRIIRTCQRLGIQTAAVYSEADAESLHVKAA
                     DEAWLIGKPRVSESYLNIEKIIETAKKAGVCAIHPGYGLLSENSRFAERCLKENITFIG
                     PPPDVIAKMGSKIEARQAMEQAGVPVVPGVTKSLSGLNEARALAESIGYPVMLKASFGG
                     GGIGMQLIRNESELEKAYEGNQKRAADFFGDGAMYIEKYIEQARHIEIQILTDKYENAV
                     YLWERDCSIQRRQQKIIEEAPAPLFDETMRTKLGEAAVKAALSIGYVNAGTIEFLVDKE
                     NHFYFLEMNTRLQVEHPVTEEITGLDLVEEQLNIAAGKPLSHKQKDIRRDGHAIEVRIC
                     AEDPKTFFPSPGRITDLKLPEQPNVRHECAAAPGMTITPYYDPMIAKMIVKGSSREEAI
                     CTLAEALSQYQVKGIKTNIPLLEDIVSSDEFRKGGVQTDFISRYQSK"
     gene            complement(16878..18515)
                     /locus_tag="B4090_RS14825"
                     /old_locus_tag="B4090_2297"
     CDS             complement(16878..18515)
                     /NRPS_PKS="Domain: AMP-binding (13-445). E-value: 3.5e-108.
                     Score: 353.7. Matches aSDomain:
                     nrpspksdomains_B4090_RS14825_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003182456.1"
                     /locus_tag="B4090_RS14825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2297"
                     /product="AMP-binding protein"
                     /protein_id="WP_003182456.1"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-115, bitscore:
                     382.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELLHLTIGKLLEKTAADAPDHEAVVYPDRGLRYTYREFDQLCR
                     KVAKGLMALGIDKGEHVAIWASNTPEWLTAQFASAKAGAVLVTANTNYQLSELEYVLKQ
                     SDATTLILMESYRGTSYIDILCKLIPELKEGEPGRLASERLPFLKNIILLGDQRHPGMY
                     LWDDLLKLSGSVSEKALDRRMERLKEHDVINMQYTSGTTGFPKGVMLTHSNLANNAANI
                     AECMNLSKKDRMCIPVPFFHCFGCVLGTLACVTAGATMVPVQEFSPKEVLSAVETEKCT
                     ALHGVPTMFIAELNDPDFASYDLSSLRTGIMAGSNCPIEVMKKVIDNMGMSEITIAYGQ
                     TEASPVITQTRVNDSLKRRVETVGRALPNVEVKITEPGTNREVERGVQGELCTRGYHVM
                     KGYYKNPEATAAVIDEDGFLHTGDLAVMDEEGYCRITGRLKDMIIRGGENIYPREIEEF
                     LYKHPDILDVQIVGVPDETFGEEVSAWIKLKSGASMTADELKEYCKGKIARYKIPRYIA
                     FVEEFPMTASGKVQKFKLREQALEHFQL"
     CDS_motif       complement(17148..17210)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS14825_0003"
                     /evalue="3.40E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="B4090_RS14825"
                     /protein_end="456"
                     /protein_start="435"
                     /score="10.3"
                     /tool="antismash"
                     /translation="TGRLKDMIIRGGENIYPREIE"
     aSDomain        complement(17181..18476)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B4090_RS14825_AMP-binding.1"
                     /evalue="3.50E-108"
                     /label="B4090_RS14825_AMP-binding.1"
                     /locus_tag="B4090_RS14825"
                     /protein_end="445"
                     /protein_start="13"
                     /score="353.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="EKTAADAPDHEAVVYPDRGLRYTYREFDQLCRKVAKGLMALGIDK
                     GEHVAIWASNTPEWLTAQFASAKAGAVLVTANTNYQLSELEYVLKQSDATTLILMESYR
                     GTSYIDILCKLIPELKEGEPGRLASERLPFLKNIILLGDQRHPGMYLWDDLLKLSGSVS
                     EKALDRRMERLKEHDVINMQYTSGTTGFPKGVMLTHSNLANNAANIAECMNLSKKDRMC
                     IPVPFFHCFGCVLGTLACVTAGATMVPVQEFSPKEVLSAVETEKCTALHGVPTMFIAEL
                     NDPDFASYDLSSLRTGIMAGSNCPIEVMKKVIDNMGMSEITIAYGQTEASPVITQTRVN
                     DSLKRRVETVGRALPNVEVKITEPGTNREVERGVQGELCTRGYHVMKGYYKNPEATAAV
                     IDEDGFLHTGDLAVMDEEGYCRITGRLKDMIIR"
     CDS_motif       complement(17283..17360)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS14825_0002"
                     /evalue="3.20E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="B4090_RS14825"
                     /protein_end="411"
                     /protein_start="385"
                     /score="22.7"
                     /tool="antismash"
                     /translation="GVQGELCTRGYHVMKGYYKNPEATAA"
     CDS_motif       complement(17880..17930)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS14825_0001"
                     /evalue="2.10E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="B4090_RS14825"
                     /protein_end="212"
                     /protein_start="195"
                     /score="23.3"
                     /tool="antismash"
                     /translation="QYTSGTTGFPKGVMLTH"
     misc_feature    complement(18537..18548)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 19.78"
                     /tool="antismash"
     gene            complement(18547..19707)
                     /locus_tag="B4090_RS14830"
                     /old_locus_tag="B4090_2298"
     CDS             complement(18547..19707)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009328128.1"
                     /locus_tag="B4090_RS14830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2298"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_009328128.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.5e-38, bitscore:
                     128.7, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 7.5e-25, bitscore:
                     83.7, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4e-54, bitscore:
                     179.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFELTREQQMIRELARDFAKQEIAPHAEHVDRTGEFPIETFKKM
                     GELGLLGIPFPESYGGSGGDTISYALSVEEIGKACGSTGLSYAAAVSLGAAPIYYFGTE
                     EQKQEYLVPLATGRALGAFGLTEPNAGSDAGGTRTKARSEGDSYVISGEKCWITNAGFA
                     RTVIVTAVTGIDDNGKNIISAIIVPTDSEGFTIKSEYDKMGVRGSNTSQLILDNVRVPK
                     QNLLGSPEKGFKQFLNTLDGGRISIAALAVGIAQGAFEAALTYARERKQFGRPISYFQA
                     IQFKLADMAMEIELARNMVLKAAWLKDQGRPFTKEAAFAKLYASEMAFRTCNQSIQIHG
                     GYGYMKEYGVERMLRDAKLMEIGEGTSEIQRLVIARQLGIGKQALK"
     misc_feature    19901..19915
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 21.72"
                     /tool="antismash"
     gene            19938..20498
                     /locus_tag="B4090_RS14835"
                     /old_locus_tag="B4090_2299"
     CDS             19938..20498
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0050136 - NADH dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003182460.1"
                     /locus_tag="B4090_RS14835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2299"
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_003182460.1"
                     /transl_table=11
                     /translation="MKTLVIVAHPNLETSVVHKRWVEELKKYPEKYTVHELSDVYPDGN
                     IDAEKEQKLVESHGNLVLQFPIYWFNCPPLLKKWLDDVLAYGWAYGSNGGDRLNNRKVA
                     LGVSAGIKEEDYRENGRYRYTLEQILVPFETTFRYCRADYRSFFAFYGKEKEPGGNEEE
                     ENEPGAGELEKSARDYLHFIDHM"
     gene            complement(20540..20890)
                     /locus_tag="B4090_RS14840"
                     /old_locus_tag="B4090_2300"
     CDS             complement(20540..20890)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003182462.1"
                     /locus_tag="B4090_RS14840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2300"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_061576747.1"
                     /transl_table=11
                     /translation="MQIPSGKTCVPTGVELKDTGFGYTLSLISGKYKIVILYWLSEREV
                     MRHNELKRSIGTISFKTLCIMLKELEADGLIIRREFPQIPPKVEYSLSERGRSIVPLLN
                     MMCEWGEKNRLG"
     gene            complement(21102..22373)
                     /locus_tag="B4090_RS14845"
                     /old_locus_tag="B4090_2301"
     CDS             complement(21102..22373)
                     /EC_number="1.2.1.41"
                     /GO_function="GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA]"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003182464.1"
                     /locus_tag="B4090_RS14845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2301"
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="WP_003182464.1"
                     /sec_met_domain="Aldedh (E-value: 1.1e-17, bitscore: 60.4,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATSESISAQIEEKAIKAKTAAKSLRLATEKEKNEALAALADHL
                     KQNMSYILTENAKDIEAGRKKGYDAAYIDRLSLNEDRVLDFADGLLEVAELDDPVGETL
                     SSWTLDNGLKAEKVSVPLGVIGMIYEARPNVTVDATGLALKSGNAIVLKGGSSAIHSNT
                     AIVSVMHQALDSTNIPRDAVQFIESTDRSATKQLFKMKEHIDVLIPRGGGALIQEVVEN
                     ATVPVLETGVGNCHIYIDREADPEKAIDVMINAKTDRPAVCNALETLIVHEKWLEENSA
                     ALINALNEHGIQVHGDEKAVQMIPGARPAGEADWQNEYLSLDLAVKVAGSLEEACDHIE
                     TYGTKHSEAIITENPETAKAFLNTVDAAALYHNASTRFTDGGALGFGAEIGISTQKLHA
                     RGPMGLKELTTCKYIMRGDGHIRR"
     gene            complement(22399..23520)
                     /gene="proB"
                     /locus_tag="B4090_RS14850"
                     /old_locus_tag="B4090_2302"
     CDS             complement(22399..23520)
                     /EC_number="2.7.2.11"
                     /GO_function="GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="proB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003182466.1"
                     /locus_tag="B4090_RS14850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2302"
                     /product="glutamate 5-kinase"
                     /protein_id="WP_003182466.1"
                     /transl_table=11
                     /translation="MTSNQQRVVVKVGSSSLTSLHGEISSKKLEKLVEQIVRLKDEGHE
                     VLLVSSGAVAAGYRKLGFINRPDTLPEKQASASVGQGLLIEAYSKLFLSHGYIASQILI
                     TKSDFSDEKRYNNVRNTMNVLLKRGIIPIINENDTVTVNRLKFGDNDTLSAKVAGLIDA
                     DLLTILSDIDGLYDANPRKTPDAALVQEVTEITPEIEASAGDAGSEVGTGGMKSKLDAF
                     KITMASGIKGFLGRADTPGILHEAICGTARGTYFIPNADSHALNHKKQWIAFNSGPEGD
                     IVVHNESKEFIIDRKKSLYPSSIYDINGRFSNGSVVRILDQEGEEIGLGVVNFSSSQLR
                     KWKKDTNQETAASSQAVVDREAFVCHLELSVPL"
     misc_feature    23554..23567
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     18.15"
                     /tool="antismash"
     gene            complement(23559..24410)
                     /gene="proC"
                     /locus_tag="B4090_RS14855"
                     /old_locus_tag="B4090_2303"
     CDS             complement(23559..24410)
                     /EC_number="1.5.1.2"
                     /GO_function="GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="proC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011201664.1"
                     /locus_tag="B4090_RS14855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2303"
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="WP_185955453.1"
                     /transl_table=11
                     /translation="MLKIFNQKNVAFIGAGSMAEGMISGIVQSKKLPASQIYVTNHTNH
                     RRLEELQQKYGIQGVKKEQLDYQNIDCFILAMKPKDAEGALNSMKPHIKPHQLIVSVLA
                     GISISFIENALNDMQPVIRIMPNTSSAIGASATAMAEGSHVTADLSKTAKQLLQCMGEV
                     YSIEESKMDIFTGIAGSGPAYFYYLMEHIEKAGAEAGLSQKLTREIGAQTLLGAAKMLL
                     ESPEDTAVLKDNITSPNGTTAAGLKALEESGGGEAIEQAVKQAAKRSKTISLELEQLVA
                     AK"
     misc_feature    24421..24436
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.84"
                     /tool="antismash"
     misc_feature    24531..24544
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.5"
                     /tool="antismash"
     gene            complement(24761..25438)
                     /locus_tag="B4090_RS14860"
                     /old_locus_tag="B4090_2306"
     CDS             complement(24761..25438)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003182471.1"
                     /locus_tag="B4090_RS14860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2306"
                     /product="DUF421 domain-containing protein"
                     /protein_id="WP_061576749.1"
                     /transl_table=11
                     /translation="MEYVHLVVELTIGFAALFLMTKILGKTQFAQITPFDYISALILGE
                     MVGNAIFDEDVTIWKVLFAILIWAVLIYSIEVLSQKVQNIRGFLEGRPSIVINKGKIDY
                     NALKKNKLDLNQLQTLAREKGCFSLHEIQYAILETDGSISVLPKHKYGMPTKDDLNIPY
                     KPVQLPVPVILDGQLEKNNLHEAGFDELWLQNQLSSQGITQYQEVLYAEWRGDEGQLYI
                     TTY"
     misc_feature    25402..25422
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.73"
                     /tool="antismash"
     gene            complement(25586..25780)
                     /locus_tag="B4090_RS14865"
                     /old_locus_tag="B4090_2307"
     CDS             complement(25586..25780)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016885415.1"
                     /locus_tag="B4090_RS14865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2307"
                     /product="hypothetical protein"
                     /protein_id="WP_235598198.1"
                     /transl_table=11
                     /translation="MELKRCRTARNKIQVCQCSAPFQQCITSGKGARAAVSVSLPEVIV
                     QKPRAVTALNSRLTEEELG"
     gene            complement(25808..26944)
                     /locus_tag="B4090_RS14870"
                     /old_locus_tag="B4090_2308"
     CDS             complement(25808..26944)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003182473.1"
                     /locus_tag="B4090_RS14870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2308"
                     /product="inorganic phosphate transporter"
                     /protein_id="WP_061576751.1"
                     /transl_table=11
                     /translation="MTITILAFIIALFFAMNIGASGAAASMGIAYGAGAVRKRQAALWI
                     SGIGVFLGAMIGGGEVVKTIGSGIIPASILNVHIVVIILGSSAISLFIANIAGIPLSTS
                     EVTVGSIVGVGVAFQAVFTDKLLVIVMYWLIIPIAAFFLAFLIGQLLKKTEAKLRWLKQ
                     QKWARLLTALVILTGFLEAFSAGMNNVANSVGPLVGAGLLSVGSGTFLGGLFVAIGAIC
                     LGSRVIETNGKKITEFSLLQGSCVSGLGASLVIGASLFGIPVPQTQITTCSIIGIGLSE
                     KGRAIFRKSVILKLMKVWVVSPVFSLVISYSLVKIFLDFDLYSVAVVLCVFLATLGSIS
                     LMKHARQKQSDVRRNRDHLKSIVGGRGRKREPAVWRDF"
     gene            complement(26959..27669)
                     /locus_tag="B4090_RS14875"
                     /old_locus_tag="B4090_2309"
     CDS             complement(26959..27669)
                     /EC_number="1.8.4.8"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0004604 - phosphoadenylyl-sulfate
                     reductase (thioredoxin) activity [Evidence IEA]"
                     /GO_process="GO:0019379 - sulfate assimilation,
                     phosphoadenylyl sulfate reduction by
                     phosphoadenylyl-sulfate reductase (thioredoxin) [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016886689.1"
                     /locus_tag="B4090_RS14875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_2309"
                     /product="phosphoadenylyl-sulfate reductase"
                     /protein_id="WP_061576752.1"
                     /transl_table=11
                     /translation="MNDVLTYSTWDEKASEEVMDTFSGEMDVLKWAYSTYQKIVYACSF
                     GAEGIVLIDLISKVVKEADIVFLDTGLHFPETYELINEVKDRYPGLSIHFLKPGLSLEE
                     QEKRYGSELWKRQPDQCCRLRKIEPLREDLSGMEAWITGLRREQSETRKHVRYINKDDN
                     FKLIKICPLIHWTWEDVWTYIKLNQLTYHKLHDQDYPSIGCEVCTLPVTDSGNLRAGRW
                     AHQEKTECGLHQFR"
     misc_feature    complement(28284..28299)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.03"
                     /tool="antismash"
ORIGIN
        1 atcatgatga cgatatgatc aggcatgacc tctcgtaata cacctcgtac agagccgtgg
       61 gtcgtttgaa cagcaaggga ttgattgtga agtcccatta aagcttgata aacatacgga
      121 tcactaagtt tccatttttc actcattttc aacacactcc tttcatgaag cccatagcag
      181 tatatgcaag gaagtaaaaa tgtgcatttg tccaattgga atgttggttt tcggatttat
      241 tcagacatcc attctttcat tagaaaaata aacccagatt ctgaatccaa aataaaaaca
      301 cctatgaaat agtgtcaggg cgtctcaatc ttaatccttg tttaactttt aaacacgggg
      361 tcctaccaac aaaaagcgca aaacatacgc taggcaaaat ttaacatgac gaaactgttg
      421 agtgacaata aagttctttc cttaccaata aagttgttta ctaatcggtt tgttttatta
      481 caataaagtc gtttgctttt accataaggt tgataaatca actgtttgaa cgcataaaag
      541 taaacaacta tttttatgca tttggcgaaa atctaaaaaa tggggttgcc agcaagattt
      601 cttcaggagg ctctcttgtg ctaaacagcc aggccaagta ccttatttca cgataacggt
      661 tgatcaattc cagcacttct ccgactttgt tttccttcat caatctctcg ctgaacaaaa
      721 tggcagagat ttgtcccaag tttaagcgtt gttgtgatgt actgtacaaa tcatttgccg
      781 cctccgtaaa cgaggaacct tcgcctttgc ccacccaaac cgggggctgc tccgcttttt
      841 gctgtccctc cagcttggcc actgtcgaga aatcaagcaa ttgcaaatac atggtgtatt
      901 ggccatcgac atagtctatt ccaacagccg tagcatagtt catgttttgc acttcatatc
      961 tgctccagca accggtaagg gtgagaagaa ggaaaagtgc aaccatactt ttatatctcc
     1021 tcatttatgc ctgtcccctt gccttgtaga atctcgtgtc ttcaacatgt ccggtcgagt
     1081 gtttcgccat ggccaaggta atcgaaacaa agcgttggcc aagtctttaa atggaggtga
     1141 tattggggcc aagtaaggca agccgcatga acgcaatgag gctaaatggc tgagcacaat
     1201 aaataatcca agaaagaagc cataaatgcc aagcgtggca gacagaatga aaagaaaaaa
     1261 gcgtaaggta ctaatcgttc cagccaatga taggctcgat aaagttgaac caaagatttg
     1321 tgtaattgct ccgatgacaa cgatacctgg ggataagaat ccagcacgaa tggccgcatc
     1381 ccccaggata agtcctccta caaccgttac cgtggagccg accgcagaag gcaatcggat
     1441 accagcttcc cgcaggattt ctaagaagag aagtgcaata aacatttcaa ctgccacatc
     1501 aaaagggatt cccaaccggt taatccccaa agtggcaagt agataatagg gcagctgatc
     1561 ttgatgatag gaaagaatgg caacaaaaaa tgcaggaagc agtagcgata cggacaagcc
     1621 aagtaaacga agcgtttgac caaatgtagc tgccaaagca gtaaagtgga tatcttcggg
     1681 tgctttcaca agcaaaaata aattggcagg cgcaatcaac gcagccggtg taccatccac
     1741 aatcaacgct acacgcccat tgagcataca gttcacggta aagtctgctc tgcctgtata
     1801 ccccatcaaa ggaaacaatg cttttgtcgg ttccattaat tcttctagct gagtggcgct
     1861 aaacgctccg tcaatgtgaa gatcatctaa tttattcttt acatcttgaa caatcttagg
     1921 atcaacaatg tcacgcatgt aaagaattgc aacggttgtt ttcgtgcgaa cgcctacttt
     1981 tttcgtttca taaaccatgc tggttgattt gattcgtttc cgaattaacg ccacattgac
     2041 tcccacttct tccacaaatc catcctttgg cccccgtacc gaaagcattc gcatcatctg
     2101 tacgttcttt caagctgcgc gtaatatctg ctgttctact cattttaatt tgcaggcctt
     2161 cataatggtt ttccaagaga tttcggatgc tatgggaaat atttaaggta atttcttttt
     2221 cctgcatccc attgccaata gctactgggt ccattctccc gtgaccagga tctaaatata
     2281 atttaaacat tttacaccac ctcgtacaaa taaaatatga tcgaagagta acggaggtat
     2341 aggaattcgt ctgagataca tataaaaata ggtgatgata ggcattacat ttcattgaat
     2401 cagatgattt attttaaagc taagaaattt tccaaatgcg agaccatatg tatgagcagc
     2461 aattaatgtt ccatattttt cgtgggtcag gcaaactctt gttcatctag acagtaggct
     2521 gattgattat tgatgcttct ttcttaacaa aacacctaag tgattctctg tgcatatact
     2581 gtatcattac tacaggatta tgattaaata caactcaatc catacataaa ataatcaagg
     2641 agaggttaat tttgaaaatt ccaaatacag ccaaagttag tatccccttt ccatccgtat
     2701 gggggattga tgcttctatt gcggggagat ccattattag aggtatactt accattgatt
     2761 ccattgtaga caacaaagta gtaggtacag ttaattttcg tggtatacct attccgatta
     2821 atgggtattg ggacgaaagc gctaaacaaa taagtttcga ttcaccatat gcctcctttt
     2881 ttggcaactt gacaataatt gatgagaccg ctataagcat tcggcatttc attttaagtg
     2941 gacggtttat aatgaaacct ccctctttgc tggctggtga atacggaaat tggattgcta
     3001 caacctttac aacccgtttg ggacctccca tatatactaa tgttttacca cctgttggtg
     3061 ccttttcagt ctcaagtatg ctcttgggac agcaattgtt ttaattagac catgacttta
     3121 taaaaacaac cttcctttgt gactaaggtt gttttttaaa agtgttctcg aaaaatacag
     3181 ccttgcttta aatctgagtt tagcgtatat ctccgttaaa atgtactcgg aaccctttga
     3241 tgatcgtgcc tagttagata aacaaatatt gatacttcct tatagaaata gcctgcttgg
     3301 ttaggtacgt tgtttcacaa tccccggaaa tttttaatat aagtaatgaa tgcttatttt
     3361 tttccttccg atagctttct atataaagaa gctctagata catttgtaat ttcacaaatt
     3421 tgatttacag tcatatttcc ttctttatat agctttactg cataattcat tcctgcgtga
     3481 tttttatgat atttctttaa ccgtccttta aacttccctt ctttctttgc gagctcaatt
     3541 ccttcacgct gacgcatctg aagatgaatg gatattgggg acctacttca ctttttccaa
     3601 acgggattta gaaatagtta ataagcgaag gagagaagaa aaccgtttag ggtttgctgt
     3661 tcaattagct gttcttcggt atcccggttg gccatacact catatcaaaa gcatcccgga
     3721 atcagtcata cattatatat cgaaacaaat cggtgccact ccatcttcga ttagtcttta
     3781 tcctcaaaga gaaaatacac tttgggatca tttgaaagaa cttcgaagtg aatacgactt
     3841 tgtaactttt actctaagag aatatcgaat agcatttaag catcttcatc aattagcttt
     3901 tgaaaatggc gatgccatac atctactaca tgaatgtata gattttctaa gaaaaaacaa
     3961 aatcatactg cctgctatta ctacacttga aagaatggtg tgggaggcaa gggcaatggc
     4021 tgaaaagaaa ctgtttaata ctgttagtca atctcttaca aatgaacaaa aaggaaagct
     4081 tgaagagatc attacttcgc agcatccatc cgaatccaat aaaacgatat tgggttggtt
     4141 aaaggaaccg ccgggtcatc cttcacccga aacatttcta aaagtaatag aacgactcga
     4201 atacatacga ggaatggaat tagaaacggt acaaattagt catttgcatc gcaatcgcct
     4261 gtttcaacta tctcgcttag gctcaagata tgagccatat gcattccgtg actttcaaga
     4321 aaataagcga tattcgatat taaccgtcta tttattacat cttactcaag agttaacgga
     4381 taaagctttt gaaattcatg atagacaaat acttagtctg ttatcaaaag gccgtaaagc
     4441 tcaagaggaa attcagaaac aaaacggtaa aaagctgaat gagaaagtta tacactttac
     4501 gaacatcgga caagctttaa tcaaagcaaa aaaggaaaaa ttagacgttt ttgaggtttt
     4561 agaatccgtt atcgaatgga attcttttgt ctcttcggtc gaagaagctc aggagcttgc
     4621 acgccctgac gactatgatt atttagactt actgcaaaaa cgattttatt cacttagaaa
     4681 atatacgcca acgctattaa gggtattgga atttcattct acaaaagcaa atgagccact
     4741 tttacaagct gttgagatta tccgtggaat gaacgaatcc ggaaagcgaa aagtgcctga
     4801 taactcacct gtggatttta tttcaaaacg ttggaaaaag catttatacg aggatgatgg
     4861 tacaacaatc aatcgtcatt actatgaaat ggctgtttta acagaacttc gggagcatgt
     4921 tagggcagga gatgtttcca ttgttggcag cagacaatat agagactttg aagaatattt
     4981 gttttcagaa gatacatgga atcaaacgaa ggagaataca agattatcag ttagtttatc
     5041 attcgaggat tatatgacgg agagaaccag cagccttaac aaaaggttaa agtggttagc
     5101 taccaattcc aacaagttag acggggtttc tcttgaaaaa ggaaagctgt caattgaacg
     5161 cttagaaaaa gatgttccag aagaagcaaa aaaatttagt gcaagcctgt atcagatgct
     5221 accaagaata aaattaaccg atttactgat ggatattgct tatataacag gatttcatga
     5281 gcaatttatt catgcttcca ataatcgaaa accggataaa gaagaaacaa ttattattat
     5341 ggctgctctt ttaggaatgg gaatgaatat tggtttaagc aaaatggctg aagcaacacc
     5401 cggacttaca tataagcaat tggccaatgt atcacaatgg cgcatgtatg aagatgcaat
     5461 gaataaagcc caagccgtat tagtaaattt tcatcacaaa ttgcaattgt cctcctattg
     5521 gggagacggt acaacatcct cgtccgatgg tatgagaatg cagataggcg tttcatcgct
     5581 acatgcagat gcaaacccac attatggaac tggaaaagga gccaccatct atcgttttac
     5641 aagtgatcaa ttttcttctt attacacaaa gattattcat actaattcaa gggatgcgat
     5701 tcacgttttg gatggtttgt tacaccatga gacggatcta aatatagtag agcattatac
     5761 agacacggct ggttacacag accaaatatt cggactgacc catttattag gatttaaatt
     5821 tgctccaaga atacgagatt tatcagactc gaaattattt acaatagata aggcaagtga
     5881 gtatccaaaa ttagaagtca ttttacgtgg acaaataaat acaaaggtca ttaaagagaa
     5941 ttatgaggat gttttgcgat tagctcattc tataagggaa ggaacagttt cagcatccct
     6001 tattatgggg aaattaggtt cttattcaag acaaaacagc ttggctacag ccttacgtga
     6061 gatgggccga atagaaaaaa cgatctttat tttgaattat atttcggatg aatcattaag
     6121 aagaaaaata caaaaaggat tgaataaagg agaagccatg aatggactgg caagagctat
     6181 tttcttcgga aaacaaggag agcttaggga acgaaccata cagcatcaat tgcaaagagc
     6241 cagtgcctta aacatcatta tcaatgccat cagtatctgg aatactttac atctaacaaa
     6301 ggcagttgaa tatcaaaaac ggtcaggtag ttttaatgaa gaattattgc accatatgtc
     6361 acctctaggt tgggaacata ttaatttact tggagaatac cattttaatt cggagaaaat
     6421 ggtctcgtta gattctttaa gacccttgaa actttcttaa cgttgttaaa actgggggaa
     6481 tagtcgggga aatgggctta gcgttgtaaa tccgcatttt cctgactgta ccccctattg
     6541 gtcggttttc accaaaaacc tccggtataa aaacagcagt atcataatgt gcagcgcaat
     6601 tccggtgatc ccgaaaacga gaaaaagccc ttcgtgggat attcccgcca agtacgtttt
     6661 cgctgtccaa taaggtgaaa acaccgaaaa gctgccacgg cacaggaata aaataaaccg
     6721 cggccggcat gagagtgagc aggctgaatc ctttcattaa agcgagtcct tccactttgt
     6781 ttgcgacata ggcggctaaa agcagcgtgt aaatcggggc ttcaagcgtg accatgatca
     6841 ggacgaacaa taggttcaca gcgccaggcg ccattagacc gccggaggca aacagcaaaa
     6901 tgctgtagca taatgtcatc gccatcggca ggatgagccg gatcatgaca tatccgcgct
     6961 tcgacaaggg cgtcacggca aaatactgaa tcatattttc gtcgcgctca tcaagcagga
     7021 taaaccccga catgacaccg agaatcaggg ggatgaaaag catggcaagg ctcatgatca
     7081 aatgacggta tggggtgata ttgaattccg tcaattccgc tgacaaagga acgcctgctg
     7141 cagtcacgat gatgagcaga aaaggcgcca gtccgtaaaa agcgagctgc gattccgttc
     7201 ttgtcagtat attttggttc aaatttacca caatattttc atttgcccgt caaatttaaa
     7261 gcaaaaaaaa gcaccactta tagtttaaac tataagtagc gcttcatttc cattaataag
     7321 ccaggctgaa cagacctttt atgtggctca ggtagcggac gttgctcgct tctttcatca
     7381 atgaagcagg caggccttta agagatgtgc tgttcgcgcc gataacggca actgcgtctt
     7441 tgcggcccag gcttgcaagc gtacctgagt tgacagggct gaacgtcgcc attgatttgt
     7501 tttctaagta tgcatacagg ttgtagccga tcagctcgcc catttgccat gcgatttgag
     7561 ctgtcggagg gtacggacgg ccatccggac cgaagacaac ggcgctgtcc cctgcaacaa
     7621 acacgtcttc atgtgatgta gattgaagga agtcgtttac agttgcgcgt ccgcggttga
     7681 cttcaagacc tgattcgccg atcagcggat tgccttgaac accgccggtc cagacaaatg
     7741 tatttgtaac aattttttgt ccgtctttca aatcaacaac gtttccttct acatttgtga
     7801 caggcagtcc tgtcaagaat tcaacgccgc gtttttcaag gctctttgtc gcacgttcga
     7861 tcagctcatc cggaagaacc ggcaggattt tcggaccggc ttcaacaagc ttcagcttga
     7921 tttctgtcgg atcgacaccg tagcttctcg caaggctcgg catgatatcg gcgagttcac
     7981 cgacaagctc gacgcctgtt agtccgccgc cgccgattaa gatcgtagca tcagcttcgt
     8041 ttttcgtttt cgcgtattcg cgcacgcgct cttcaacatg cttgaagatt ttgtttgcat
     8101 cgtttgcaga tttgagcacc atgctgtttt cttcaagtcc cggaatgccg aagtaagcag
     8161 tgacagaacc aagaccgacg acaagtgcgt catatgtcag ggtagagccg tcagaaagag
     8221 cgacttcttt tttgtcaact gagaaagagt tgactttggc gattttaaga tcgatgtctt
     8281 ttcctttgaa aagctttgca agcggcatcg caactgcctg ttctgacacg ttgcccgcag
     8341 caaggcggtg caattccgtg atgatttgat gtgtcggata ttggttaacc actgtgactt
     8401 ttgcttcttc ttttgtgtag tgtttgcgaa ctgttagagc agacagtaat ccgccgtaac
     8461 cagcgcctaa aatgacgata tgttttgaca tcgtgaatcc tccgtcctta ttctgaatgt
     8521 atagtgatta tttttgtttt tcgcgttctg acatgatttg caggtagctt tgaacaaagc
     8581 ggaacagctt ttgggcctgc ggatctttaa gcattttcag caaaccgaaa agtccgatga
     8641 cttcattgct ttcgtcagcg cggtcttttg cttcaatggc ggtagccgcg atttcttttg
     8701 ccgtatcttt gacaggctca agaatttctg taatggcacc gaccgtatca ttttttaata
     8761 cttcatcagt tgcaacggat tgtgcgaagt cgtaagactt tgtcaaaatg ttgacaagtt
     8821 ctgtcagctt tggaagctgg tcgactaaaa cagtcaaaga ctcctgtact tcaggtttta
     8881 gcagttgatc gataagatcg cgttggcttt ggcttacaga ttcgtttgtt tgatcagctg
     8941 tttgatcgat tgtttccggc ataaccaatt ctccttttca ataagcgatg tgctgttttt
     9001 tgaaggaagc ccctttttat agtttgtgaa tttatgcaca aacaagtccg caaaaaggct
     9061 ctcccctttt gtgtttgttt tgctgttttc ggtctggaac tcccgaaaac ccgcaatctc
     9121 aaaacacgct gtatttttta ctactaaatg ataacacttt ttgaacaaaa aatgaacgtg
     9181 attgtttcgg aaatgaaata aaatcataga aaactttata tatagggctt ctttcatccc
     9241 tttcatttcc tatattgtgt ctttttttac gaaacgcccc attcacacgg gataatagag
     9301 acggaaaacg tgcgaaactt tcatagaatc gtatctgtca gtttacataa taaagttatt
     9361 gttatcccgg gttaatcttc atctttgacg tccggatctt cggggatggg ctcgttcaga
     9421 acggattccg cccactcttt atacttttcc atctgttcca tgtgcgtatt gaattgctct
     9481 ttgttgatta aatgctgctg tccgtcaaag acggtgcgga ttttcttttc tctgacaagc
     9541 tgttcaacat atgcttctga aagcgttaaa tattctgcgg tttcctttat cgtcaagtac
     9601 atgttttgtt tcctctcgtt ttgatttagg cgaacattgc gattgtagga tcatacgata
     9661 aggtatatca gtttagatga tggaggccta ttctatgtat tcaaaatgga attctgaaac
     9721 gtcttatccg ccttcagccc cgcaaatgca taccggtcaa tcttcgcagc agatgaacca
     9781 aaggctgaaa aatctcgaag atcaaatgga attgctcatc aagctcatgg aaagcaacaa
     9841 tcagctgctg cgttcgattg aagagcagca gaatcgcgtc tgcacggccg gcggcggttc
     9901 ggttatcgtc aggatgtgag tgttggtcga tcgagcttca tcaaaataaa aagaggaagg
     9961 acgtgtcctt cttctttgtt tgtaagcctt atccagtata ctacagattt tttcgcactg
    10021 aaagaccggc aatttcatca tatgtttcgc ggttttccaa agttgacaaa tcgcctgcgg
    10081 gctcgttcat ataggcagct ctgatcagcc gtctcatcac ttttgcattt ctcgtcttcg
    10141 gcaaaccgct gacaaaataa accgctttgg gcttgaccgc tttaccgatc gcatcagatg
    10201 caaggttcag caaatcatct tttaattctt ccgacggctt ttccgactgt ctgaggacga
    10261 cgaagcagac ggcagcctgg cctttgagct tatccggaac gccgatgacg cctgcttccg
    10321 ccaccgctgg atggccgacc agaacggact ctatttcggc ggggccgatc cttttcccgg
    10381 cagcattgat cacatcatca gagcgtccgc tgatcgtcca gtagccgttt tcatcccgtt
    10441 ttgcccaatc gccgtgcacc catacgtcgg tccagcggct ccaatatgct tcttcgtatc
    10501 ttgacggctc cttccaaaaa ccgttcgtca tgccgaccca gggctttgtc aggacaagct
    10561 ctccgacttc attgacgact tcctctcctt tttcattgaa gacattggcc gccatgccgg
    10621 gaagaggcga attaaacgtc atcggcgtga tcggccgcag gagcacattg cctaaaattc
    10681 cgcctgagat ctctgttcct cctgaataat taaatatagg aatccgttct tttccaacat
    10741 ggcggaacag ccacatccac ggctcataat tccatggttc gcccgttgag ccgattgcct
    10801 tcagactgtt cagattgtat tgatagagaa aatcttcgcc gtgctgcatc agcgagcgaa
    10861 tgagcgtcgg agagacgccg agatgcgtca cccggtgtct gctgacaagc tcccacagcc
    10921 gatccggggc cgggtagtcc ggtgctccgt caaacagcaa aacagccgct ccgtttatga
    10981 ggcccccgaa tattaaaaac ggccccatca tccagcccat gtctgtaaac cagaaaaatg
    11041 tgtccccttg tttgacatcc atcccgaatc ccgcatcaaa tgcagctttc agcggaaaac
    11101 cggcatgggt atgaaccgct cccttcggct gtcctgtcgt ccctgatgtg tatagcagca
    11161 tgagcggatc tgaactgtcc atttcttcgg tgttttgcat gggctcgttt ttcatcaatt
    11221 cattccagtc gatatctctc ttataattcc aatcttgatc gccgccgtga agcttgcaga
    11281 cgacgacttt ttgaacagtg ggggaacggt ccgcggcttt gtcagcttct ttcttcatgc
    11341 agaccttctt tccccttcgc aaaaaggcat ctgctgtgac aaggattttc gctccggcag
    11401 cggtaagtct cgccgctgct gcatgggcgc cgtagcctga aaaaaccggt gagaataccg
    11461 ctccgatttt agcggcggcc agcatggcga tgaccgtttc ggggatcatc ggcatgtaaa
    11521 tcgcaatgac atcccctttt gagatgcctt gctttttaaa gcctgccgcc gcacgggcga
    11581 cttgttggtg taaagaagaa taggtgatct gttctgtttt tccgtcttca ctttcccaga
    11641 tgagtgccgt cctgccggcc gtatcaggcc ggcgggccca tttttccacg gcgttgtaaa
    11701 cggcatttaa gcggccgccg gtaaaccatt gcggccattt tatgcctttg tcgagattca
    11761 atgtttggct gtaccgcttg taccaggtga tcccgagcgc tttttcggcc tcttcccaga
    11821 accaggcgat atcgtttgta cttgctttca aaaaatcatc atagtcggaa aaaccgaggg
    11881 ctgtcatcca ttgaaacagc cgggttgttt ttacaaattc cggatcaggc tgccaaaccg
    11941 ctttttcgcc catgccgttt cctccttttc gtttcattgg cctttagacg ggataaacag
    12001 gatgcttccg ttccgtaaat gtcatgtatt tggtcatata tgcattcagc cgtttgatga
    12061 gttccgttcg cagcgagtcg gccggaatga tcccgtcgac aatcatttct gaagcaagcc
    12121 ggtaaatgtc tatgtctttt tggtactctt tccgtttttc ggcgatgaat gcggaccgtt
    12181 cttcttcagg caattctgcg atttttttag cgtaaacggc atttaccgct gcttccgggc
    12241 ccatgacggc aatttgcgcc gtcggcagcg ccagacagca gtcaggttca aaggccggac
    12301 cggccatcgc atacaagcct gcaccataag ctttcctgac gatgacggat attttcggta
    12361 cggttgcttc ggccatcgct gaaatcattt tcgcaccgtg tctgatgata cccgccctct
    12421 cgactttcgt tccgatcata aaaccgggga tgtcagccag aaacagcagc gggatatgat
    12481 aggcatcaca caaattgata aactttgcgg ccttgtctgc cgaatcgtgg aacaaaacac
    12541 cgcctttgac ccgcggctga ttggcaatga tgccgacagg ctgcccgtga atccttgcca
    12601 aaccggtaat cagctctggc gcgaacaatt ttttgatctc ataaaaagac gcttcatcaa
    12661 tgatccgatc gattaaatcc atcatctgaa acggagcgtt ttggtttttc ggaatgatgt
    12721 cctccaatga ccggtcaaac ggacgggcgg attttgcttc aatgacaggc gctttttcgg
    12781 tgtagttcga cggaaagtag gaaagatacc ggcgcgccga cttgatcgca tcttcttccg
    12841 tgtcggcaag aatgtctccg cagcctgaaa cagaacagtg cattctcgcg ccgcccattt
    12901 cttcaagcga tactttttcg ccgatcacca tttccgccat gcgcggcgag cctaaataca
    12961 tcgaggcgtt accttcgacc atgatgacga tgtcgcaaaa agccggtatg taggcgcctc
    13021 ctgccgctga aggcccgaac aagagacaga tttgcgggat gcgcccggat aatttgactt
    13081 gctgataaaa aatccgcccc gctcctcttc gccccggaaa catgtcaact tgatccgtaa
    13141 tccttgcgcc tgccgaatcg accaaataaa gaagcgggca attcagtttt tcggctgttt
    13201 cctggatgcg gatgattttt tcaacggttc tcgctcccca tgatcctgct ttgacagttg
    13261 aatcattggc catgacgcaa acggttcgcc cgccgatttt tccgattcca gtgacgactc
    13321 catctgccgg tagcccgtca gccatgcaat tggcaaaaaa cgcgtcctct aggtcgagtc
    13381 cttcgtcaag cagcagcttt aatcggtctc tgacaaataa tttccctttt ttcttattag
    13441 cttcatggta tttctccgcg ccgccctcct gaatccggcg gatgcgttca tacaattcct
    13501 tttcggccgg catcggctgt ccctccgttc gttttattct cccgtataat ccggcttccg
    13561 cttttctgca aaagctttca gcccttctgt cctgtctttc gtcggaatcg tcagttcata
    13621 ggctttttgt tcaatggcaa gccctgtttc gatagctgtc tcaaggcctt gattgatggc
    13681 aaacttcgct tgtctgacgg ctaccggtcc gttcgccgcg atgttcgccg cgatgctttc
    13741 actcgcttcc tttaacttcg aaagcggaac gacatgttca accaggctga tcttttgcgc
    13801 ttcttcggcg ctgatgcggc agccggtaaa gatcatttct ttcgcctttc ccctgccgat
    13861 caagcggggc agccgctgtg tccctcctgc ccctggaatg attgcgagcg ttgtttcggg
    13921 gaggccgagt tcaatatgtt cggctgcgat cctgatgtcg cacgccaatg caagctccag
    13981 cccccctcct aaagcgcttc cgtttaatga agcgatgacg ggctgcggca gtttttccgt
    14041 ttcgctgacc acgcgttgaa tcagggaaac agcctgcttc gcttctgttt ggctcatgcg
    14101 ggctctttcc tttaaatcgg cgcctgcaca aaacgtcctg tccccttttc ccgttatgat
    14161 gacacagcgg acggccgggt ttgaacgaat atctcgaagg atgcgctgaa agtcgtcgag
    14221 aagcccaagc gagagggcat ttgcagcctg cggcctgttc agcgtcaaca cggcgaccga
    14281 ctgctcgttt atggaataaa gaacattggg ctccattcgg tcttcctcct cttcatcaat
    14341 gaaaacagtt ctttgattta gccgcctgca aatttcggct tggcagctct cttccggttt
    14401 tgtcttcgat ccatttagca gctgaaagca gcttgctgag atcaactccg gtttcgatgc
    14461 ccatctgggc gcacatgtag atcaaatcat cagttgccgc attccccgtg gctcccggtg
    14521 cgtaaggaca gccgcccagc ccgccgcatg atgagtcaaa tacggtgatt cccatgtcca
    14581 tcgctgcgat catgttggcg agcgccatcc ctctcgtatc atgaaaatga agggcgatat
    14641 tctcttttgg aaagcgcttt aagaggactt caagcaccct ttgaacctgt acgggatttg
    14701 ctgcgccgat cgtatctccg agggaaagtt cgttgatccc catgtcgaac agcgtttcag
    14761 atgtccgtat aatttgttcc aatggcacgt gatgttcata aggacagcca aatactgtgg
    14821 acaggtatgc tctggcggtg aggctcgctt gttttgccgc tccgatgact tccttcagga
    14881 cgggaagcgt ttccccgatc gatttgttaa tatttttccg gttgtgtgtc tcgcttgccg
    14941 acatgaaaac agaagcttca tcgatccctc cttcgagagc ccgttccagc ccttttcggt
    15001 tcggaatcag ggctgcgtag gtgacgcccg gcttccggtt gatccctttg gcgacatcaa
    15061 gggcatcaga cagtgcagga atccacttag gatggacgaa tgaagtgatt tcgatatacg
    15121 aaagccctgt ggcagaaagc atgtcgatcc aggtaatttt atcagctgtc gaaagtgcgg
    15181 tttgttcatt ttgcagaccg tcgcgcggcc cgacttcttt aatgaaaatg ttcttcggta
    15241 cgtccatttg ccatcctcca gatcttattg aagctccaat aagacatccc cttcatcggc
    15301 aaaatcacct tcgttctttc tgacggtttt gactgttccg gccgtttcgg cgacaatcgg
    15361 aatctccatc ttcatcgatt ctaaaatggc gacttcctgc cccttttcga ttttgtcccc
    15421 cgctttcact aatattttcc acacgtttcc cgccatattg gtgacaacag tattcatagt
    15481 acgcctcctt gatttcattt tgactgatag cgactgataa aatcggtttg gaccccgcct
    15541 tttcggaatt cgtcagaact tacaatgtct tcaaggagcg gaatgttcgt tttaatgcct
    15601 ttcacttgat attgtgaaag cgcttcggcc aatgtgcaga tggcttcttc tctgctgctt
    15661 cctttgacga tcatcttggc aatcatcggg tcgtaatacg gggtgatagt catacccggg
    15721 gctgctgcgc attcatgacg gacattcggt tgctcaggca gcttaaggtc ggtaatccgc
    15781 cccggcgaag ggaaaaatgt tttcggatct tcggcacaga ttctgacttc gatcgcatgt
    15841 ccgtcccgcc gaatgtcttt ctgcttatgg gaaagcggtt ttcccgctgc gatattgagc
    15901 tgttcttcga caaggtcaag ccctgtaatt tcctctgtca ccgggtgttc gacttgcagg
    15961 cgggtattca tctcaagaaa ataaaaatga ttctccttgt ctactaaaaa ctcgattgtc
    16021 ccggcgttga catagccgat cgacagcgca gctttcacgg ccgcttcacc gagctttgtg
    16081 cgcatggttt catcgaataa cggagcaggt gcttcttcga tgattttttg ctggcgtctc
    16141 tgaatcgaac agtcccgctc ccaaagatag acggcatttt cgtatttgtc tgttaaaatc
    16201 tgaatctcga tatgtcttgc ctgttcgata tatttctcga tgtacatagc cccgtctccg
    16261 aaaaaatcgg cggctcgttt ttggttgcct tcatatgctt tttctaattc gctttcattg
    16321 cggatcagct gcattccgat gccgccgccc ccaaaagaag ccttgagcat cacgggatag
    16381 ccgatggatt cggcaagagc ccgggcttca ttcagaccgg acaagctttt tgtcacgccg
    16441 ggaacgacgg gaaccccggc ttgttccatc gcttgtcttg cttcaatttt gcttcccatt
    16501 ttggcgataa cgtcaggcgg cggaccgata aacgtaatat tctccttgag gcacctttcg
    16561 gcaaaacggc tgttctcgga aagcaggccg tatcccggat gaatggcaca gacccccgct
    16621 tttttagcgg tttcgatgat tttttcaata tttaaatagc tttcactgac ccgcggtttg
    16681 ccgatcagcc aggcttcatc cgcagctttg acatgcaggg actccgcatc cgcttcagag
    16741 tagacagcag ccgtctgaat accgagccgt tgacaagttc ggatgatccg gagggcgatt
    16801 tctccccggt tggcaatcag tactttctta aacaaaaagg tccctccttt tatgttagtc
    16861 gcgcttgaaa gagaaaatta caattgaaaa tgctcaagcg cctgctccct taacttgaat
    16921 ttttgcactt tccctgatgc cgtcatcggg aactcttcta caaatgcgat atagcgcgga
    16981 atcttatagc gggcgatttt gcctttgcag tattctttta attcgtcagc cgtcatcgat
    17041 gctccgcttt tcagtttgat ccaggccgat acctcttcgc cgaatgtttc gtcaggcact
    17101 ccgacaattt ggacgtcgag aatgtcggga tgcttgtata aaaactcttc tatttcccgc
    17161 ggatatatgt tttcaccgcc tctgatgatc atgtctttta atctcccggt aatccggcag
    17221 tagccttctt catccattac ggctaaatct cccgtatgca aaaatccatc ctcatcgatg
    17281 accgctgccg tggcctcagg atttttgtag tagcctttca taacatggta gccgcgtgtg
    17341 cacagctcgc cttgaacgcc tctttcaacc tcccggttcg tacccggttc agttattttg
    17401 acttctacat tcggcaaagc gcgccctacg gtttcgaccc ttcttttgag cgaatcgttg
    17461 accctagtct gggtaatgac cggtgaggct tccgtctgtc cgtatgcaat cgttatttca
    17521 gacatcccca tgttatcgat cacttttttc atgacttcga tcggacagtt tgaaccggcc
    17581 atgatgcccg ttcttaaaga agacaggtca tatgatgcga aatctggatc attcagttcg
    17641 gcgatgaaca tggtcggtac accgtgaagc gccgtgcatt tttccgtttc gacggctgaa
    17701 agcacttctt tcggactgaa ttcttgtacc ggcaccatcg tcgcgccggc ggtgacgcaa
    17761 gcgagagtcc ccagtacaca gccgaagcag tggaaaaacg gaacggggat gcacattctg
    17821 tcttttttcg ataaattcat gcattccgca atatttgccg cattgtttgc caaattggaa
    17881 tgggtgagca tcacgccttt cggaaagcct gtcgtacctg atgtatattg catattaatg
    17941 acatcatgct ctttgagccg ttccatcctg cgatcaagcg ctttttcgct tactgaccct
    18001 gagagcttta ataaatcatc ccataggtac atgccgggat gcctttgatc ccccagcaaa
    18061 ataatatttt ttaagaaagg cagtctttca gatgcaagcc tgcccggttc gccctccttt
    18121 aattcaggaa tcagtttgca aaggatatca atgtaggaag tgccccggta tgattccatt
    18181 aaaatgagtg ttgtggcatc tgactgtttc agcacatatt caagctctga taattgatag
    18241 ttcgtgttgg ctgtgactag tacagcaccc gcttttgccg aagcaaactg ggcggtgagc
    18301 cattccggag tattggaagc ccaaattgcg acatgttcac ctttatcaat accgagcgcc
    18361 atcagtcctt ttgcgacttt tctgcacaac tggtcaaatt cccggtacgt ataacgcagg
    18421 ccgcggtccg gatagacgac agcctcgtga tcaggggcgt ctgccgcggt tttctccaat
    18481 aactttccaa ttgtcaaatg gagcagctct gccaacgttg tccctccctt ccgatagaaa
    18541 gcgttttcat ttcagcgctt gtttgccgat gccgagctgc cttgcgatga cgagccgttg
    18601 aatttctgaa gtgccttcac cgatttccat taattttgcg tcccgcagca tgcgctccac
    18661 tccatactct ttcatatacc cgtatcctcc gtgtatttga atggactgat tgcatgtcct
    18721 gaacgccatt tctgaggcat aaagcttggc aaaagccgct tcttttgtaa acggacgtcc
    18781 ttgatctttc agccaggcgg ccttcagcac catattgcgg gcgagctcaa tttccatggc
    18841 catgtcggca agcttgaact gaatcgcctg gaaataagag atcggtcggc cgaattgttt
    18901 tcgttcgcgc gcgtatgtga gcgccgcctc aaatgcgcct tgggcaatac cgacagccag
    18961 cgctgcgatc gaaattctgc cgccgtcaag tgtattgaga aattgtttaa accctttttc
    19021 cgggcttccc aatagatttt gttttggtac gcggacattg tccaatatga gctgtgatgt
    19081 attggagccg cggacaccca ttttgtcata ttcgctttta atggtgaagc cctccgaatc
    19141 tgtcggaacg atgatggcgg aaatgatgtt ttttccgttg tcatctattc cggtgacggc
    19201 ggtgacgatg acggtcctgg caaatcctgc atttgtgatc cagcatttct caccgctgat
    19261 cacatagctg tccccttccg agcgggcttt tgtccgggtg ccgcccgcat cggaacctgc
    19321 attcggttcg gtcagcccaa atgctccgag cgcccggccc gtcgcaagcg ggacgagata
    19381 ttcttgtttt tgttcttcag tgccgaaata ataaatcggt gcagccccga gcgatacagc
    19441 cgcagcatag ctaagaccgg tgcttccgca cgctttgccg atttcttcga cgctaagtgc
    19501 ataggaaatc gtatctccgc ctgaaccgcc gtagctttca ggaaacggaa tccccaagag
    19561 gccgagctcc cccatttttt taaatgtctc aatcggaaat tctcccgtcc tgtcaacatg
    19621 ttcggcgtgc ggtgcaattt cctgtttcgc aaaatctctt gcgagttcac gaatcatttg
    19681 ctgttctctg gttagttcaa aattcataaa gtgcccccct ttttggatcg tcaaattcct
    19741 taggcagcag agctttgtaa cattatatta aaaaagtgca tttttcatgc cagaggattt
    19801 tggacaggta aattgcatgt ttgatcgcca acaggtactt acctttatgt aagtacctga
    19861 actaaaagtg catacttaca aattggcagt gtgaacttta tactcaagat gaaaacatgc
    19921 tgaaggaggg caaatctttg aaaacgctag ttatcgttgc acatccaaat ttagaaacat
    19981 cagtggttca taagcgctgg gtagaggaac tcaaaaaata tccggaaaag tatacggttc
    20041 acgaattgtc cgacgtttac ccggatggaa acatagacgc ggaaaaagaa caaaaattgg
    20101 tggaatcgca cggcaatctt gttttgcaat tccctatcta ttggtttaac tgtccgcctc
    20161 ttcttaaaaa atggcttgat gatgtattag cttacggctg ggcttatggt tcaaatggag
    20221 gagatcgatt aaacaatcgt aaagtggcat taggtgtatc cgccggaatt aaagaggaag
    20281 attatcgtga aaacggaagg taccggtata cgcttgaaca aatattagtt ccatttgaaa
    20341 cgacattccg gtattgccgc gcagattatc gttcattttt tgcattttac ggcaaggaaa
    20401 aagagcctgg cggaaacgag gaagaagaaa atgagccggg agcaggagaa ttggagaaaa
    20461 gcgcacgaga ttatttgcat tttattgatc atatgtagca aggggttttg ctgaaaatca
    20521 ttcgggctga aacaggctgt cagcccagcc tgtttttctc cccccactca cacatcatat
    20581 ttaacaaagg cacgatggag cgtccgcgtt cagataatga atactcaacc tttgggggga
    20641 tttggggaaa ttctctgcga atgataaggc cgtctgcttc cagctctttt aacatgatgc
    20701 atagcgtttt gaaggaaatg gtgccgatgc ttcgcttcaa ttcattatgc cgcatcactt
    20761 cgcgttcaga cagccaatat agaatgacta ttttatattt gccgcttatc aatgacaacg
    20821 tatagccaaa gccggtgtct ttaagttcca caccggtcgg aacgcaggtt tttccggatg
    20881 ggatttgcat aacgcacact ctccttctga ctcttatatc atagatcatt atgtaatgtg
    20941 attgaaagga tgtaaaggga ggagtttgaa aggtgcctgg taaataaatt ctgcgcctgc
    21001 atgttttatg aggatgtaaa ttcagccgaa aaaaactgca cctccggatt gtcagatggt
    21061 gtctgacaaa ccaggtgcag tttcagtaca ggtctcttta tttatcttct gatatggccg
    21121 tcgcctctca tgatatattt gcatgtggtc aattctttca gacccatagg tccgcgggcg
    21181 tgaagcttct gtgtagaaat cccgatttca gcgccgaatc cgagtgcgcc gccgtcggtg
    21241 aacctggttg aggcattgtg gtacaatgct gcagcatcaa cggtattcag aaaagctttg
    21301 gctgtttccg gattttcggt gataatcgct tctgaatgct ttgttccgta tgtttcgata
    21361 tgatcgcagg cttcttcaag acttcctgcg actttaaccg cgagatcaag gcttaaatat
    21421 tcgttttgcc aatcggcttc ccctgctggt cttgcgcctg gaatcatttg aacagccttt
    21481 tcgtccccgt gaacttgaat cccgtgttcg tttaaagcat tgataagcgc ggcgctgttt
    21541 tcctcaagcc atttttcgtg gacgatcagc gtttcaagtg cattgcagac ggcggggcgg
    21601 tctgttttcg cattgatcat gacatcgatc gctttttcag ggtccgcttc ccggtcaata
    21661 tagatgtggc agttgccgac tcccgtttca aggaccggaa cggttgcgtt ctcgacgact
    21721 tcctgaatga gggccccgcc tccccggggg atgagtacat cgatatgttc tttcatctta
    21781 aagagctgct tcgttgcgct tcggtctgtg ctttcgatga attgaacggc atcgcggggg
    21841 atgtttgtcg aatcaagcgc ttgatgcatg accgatacga tcgctgtatt cgaatgaatg
    21901 gcggaagagc cgcctttcaa aacgatcgca ttgcctgatt ttagagcaag cccggtcgca
    21961 tcgacagtta cgttcggacg cgcttcatag atcatgccga tgacgccgag aggaacgctg
    22021 actttttccg cttttaaccc gttgtcgagc gtccagcttg atagcgtttc tccgaccgga
    22081 tcatcaagtt ccgcgacttc cagcagccca tcggcaaaat ccagaaccct gtcttcattg
    22141 agcgacaggc ggtcgatgta ggctgcatca tagccttttt ttcgtcccgc ttcgatatct
    22201 ttggcatttt cagtgagaat atagctcatg ttttgtttca ggtggtcggc caatgcagca
    22261 agcgcctcgt tcttttcttt ttcagttgcc agccgcaaag attttgcggc cgtttttgcc
    22321 tttatcgctt tttcttcgat ttgtgcactg atgctctcgc tcgtcgcagt catgtcaatt
    22381 cctcctttga tttgtttttt aaagcggaac ggatagctct aaatgacaga caaacgcttc
    22441 tctgtcaacg acagcctgtg aggaagcggc tgtttcctga ttcgtatcct tcttccattt
    22501 acgaagctgg gatgaggaaa agttgacgac gccgaggccg atttcctctc cttcctgatc
    22561 aaggattcga acgacggatc cgttgctgaa acggccgttg atgtcgtaaa tactagaagg
    22621 atacaggctt tttttacggt cgataataaa ctctttgctt tcgttgtgga cgacgatgtc
    22681 tccttcaggt ccagagttaa atgctatcca ttgcttttta tggttgaggg cgtgtgaatc
    22741 cgcattcggt ataaaatacg ttcccctcgc agtcccgcag atcgcttcgt gcaaaatgcc
    22801 gggggtgtcc gcgcgcccta aaaacccttt gatgcctgaa gccattgtaa ttttaaaagc
    22861 gtccagtttg gacttcatgc cgccggttcc gacttcgctt cctgcatccc ctgctgaagc
    22921 ttctatttcc ggcgtgattt cagttacttc ctggacgagt gcggcgtccg gcgtttttcg
    22981 cggattcgcg tcataaaggc cgtctatatc agagaggatg gtcagcaggt cggcgtcgat
    23041 cagacccgcc actttagcag aaagcgtgtc attgtctccg aatttgagcc gattgacggt
    23101 aaccgtatca ttttcgttga tgatcggaat aatgccgcgt ttcagcagca cgttcatcgt
    23161 atttctcaca ttgttgtacc gtttttcatc tgaaaaatcg ctttttgtga ttaaaatttg
    23221 tgaagcgata tagccgtggg ataaaaaaag cttggaatac gcttcgatta ataagccttg
    23281 gccgacagaa gcggatgctt gtttttcagg caatgtatcc ggcctgttga taaagccgag
    23341 cttccggtaa ccggctgcta cagcgccaga tgaaacaagg aggacttcgt gtccttcatc
    23401 tttgaggcgg acaatctgct caacgagctt ttcgagcttt ttgctgctga tttcgccgtg
    23461 aagacttgtt aaagaactgc ttcccacttt gacaactacc ctctgttgat tagaggtcat
    23521 tttatcactc ctgtagtatt tttcttcgtt acgggcattt actttgctgc gactaattgt
    23581 tccagttcga gactgatcgt tttggatcgt tttgcggctt gtttgaccgc ctgttcgatc
    23641 gcttcgcctc cgccgctttc ttccaaggcc tttaaaccgg cggcagtcgt accgttaggg
    23701 gaagtgatgt tgtctttgag aacagctgta tcctcagggc tttccaacag cattttggcg
    23761 gcgcctaaca atgtctgcgc gccgatttcc cttgttaatt tttggcttaa tccagcctcg
    23821 gctcccgctt tttcgatgtg ctccattaaa taataaaagt aagcaggccc gctgccggca
    23881 atgccagtga aaatgtccat tttgctttct tcgatggaat agacttctcc catgcattga
    23941 agcagttgtt tcgcggtttt tgacagatcg gccgttacat ggcttccttc ggccatggcg
    24001 gttgcagatg cgccgattgc acttgaggta ttaggcatga ttctgatgac cggctgcatg
    24061 tcgttcagcg cgttttcaat aaatgatatt gatatgccag ctaaaactga cacgataagc
    24121 tgatggggtt tgatatgcgg tttcatggaa ttaagagcgc cctctgcatc tttcggcttc
    24181 atcgccagga tgaagcaatc gatgttctga tagtcaagtt gttctttttt gacgccttgt
    24241 attccatatt tctgctggag ttcttctaaa cgccggtggt tcgtgtggtt tgtaacatag
    24301 atttgcgaag caggcagttt tttggattga acgatgcctg agatcattcc ctctgccatt
    24361 gatcccgccc ctataaaagc tacgtttttt tgattaaaga tctttaacat ctccctttgt
    24421 tcgcatttct gttcgtattt ttcgaacacg gttagtatat taacacttta gatcattatg
    24481 tcaagtttgc gtgttttgct tggacggcgc agagcatgtg aaaaatggag atttttgaag
    24541 aaaaaaggaa aagaaaagga ggctgaaggc agattcttca tcttcatgtg caccttttgt
    24601 cgtttgtcat ccggccattt gaaggccgtt tgaatgattt aacggaattt tttggagatc
    24661 aacagccttt cggaccggta aaaaagtatg ttcctcgagc cttgtgaatg caattgaaaa
    24721 agcgcgggtt cgaagcttgt cgaacccgcg cctgccaaca tcaatatgtt gtgatgtaaa
    24781 gctgcccctc atcaccgcgc cattccgcat acagcacctc ttgatactga gtgataccct
    24841 gacttgataa ttgattttgc agccaaagct catcaaatcc ggcttcgtgc agattgttct
    24901 tttcgagctg gccgtcgagg attaccggca ccgggagctg aaccggtttg taaggaatgt
    24961 ttaagtcatc ttttgtcggc atcccgtatt tgtgttttgg gaggacgctg atcgaaccgt
    25021 ctgtttccaa gatggcgtat tggatctcgt gtaaggaaaa acagcctttt tcacgtgcca
    25081 atgtctgcag ctggttcagg tccaatttgt tctttttaag ggcgttgtaa tcgatttttc
    25141 ctttattgat gacaatgctc ggcctgcctt cgagaaaacc tctgatgttt tgcacttttt
    25201 gcgataaaac ttctattgaa tagattagaa cggcccaaat gaggatggcg aaaaggactt
    25261 tccagatggt gacatcctca tcgaaaatcg cgtttccaac catctcgccc aatattaaag
    25321 ccgaaatata atcaaacggc gtaatttggg caaattgggt ttttcccaga attttcgtca
    25381 tcagaaacaa tgctgcaaac cctatcgtca gttcgactac caagtgtaca tattccatca
    25441 aggttccctc ccgaatctct ctcctcattg ttaacaatcg ggatgcagtt taaaccagag
    25501 gaatactttt cctgagaaat ggaccgactg atgatcctct gaaacgtcgg ggatcagcca
    25561 aaacaatcgt caaaaaagag cggcgtcagc cgagctcttc ttcggtcaaa cggctgttaa
    25621 gtgccgtaac cgctctcggc ttctgcacga tcacttccgg caatgaaaca gatacagctg
    25681 cacgggcgcc ttttcccgat gtgatgcact gttgaaaagg tgcactgcat tgacagactt
    25741 gtattttatt ccgggcagtt cggcagcgct ttagctccat atcatccaaa acaggcggcc
    25801 aggttaacta aaagtccctc catacggcag gttctctttt acgtcccctc cctccaacga
    25861 ttgatttcaa atgatcccta tttcttcgga catctgattg tttctgcctg gcatgtttca
    25921 taaggcttat agatcctaaa gtggcaagaa aaacacataa aacaactgcc actgaatata
    25981 aatcaaaatc gagaaagatt ttcacgagac tgtaggaaat gacaagtgaa aaaaccggtg
    26041 acacaaccca tactttcatt aacttcaaaa tgacgctttt acgaaaaatt gcccttccct
    26101 tttcagaaag gccgatcccg atgatgctgc aagtcgtaat ctgagtttgc ggcacgggaa
    26161 tgccgaatag cgaagcgccg atgaccaggg acgcaccgag ccctgaaaca caggaccctt
    26221 gcaaaagcga aaactcggtg attttttttc cgttcgtctc aatgactcgg cttccaaggc
    26281 aaatggcccc gatagccacg aacagccctc caagaaacgt tccgctgccg actgacaaga
    26341 ggcctgctcc aacgagaggt ccaacggaat tggcgacatt gttcattccc gccgaaaaag
    26401 cttctaaaaa cccggttaaa atcaccagcg cagtaagcag ccgcgcccat ttttgctgtt
    26461 tgagccaccg cagcttcgcc tcagtctttt tcagcaattg tccaattaaa aaagcgagaa
    26521 aaaatgcggc aatcggaatg atcagccaat acatgacgat caccaaaagc ttatcggtaa
    26581 ataccgcctg aaacgcgacg ccgaccccga caatcgagcc gaccgtcacc tcgctggttg
    26641 aaagaggaat cccggcgatg ttcgcgataa acagcgaaat cgcggatgat ccaaggataa
    26701 tcacgacaat atgcacattg agaatagacg cgggaatgat gcctgaaccg attgttttca
    26761 caacctctcc tccgcctatc atggcgccca gaaatacgcc aattccgctg atccacaagg
    26821 ccgcctgcct tttcctgacg gcgcctgcgc catatgctat tcccatcgac gctgctgctc
    26881 cgctcgctcc tatgttcatg gcaaaaaaca aagcgataat gaatgccaaa attgtaatcg
    26941 tcatttttta cccagctcct accggaattg atgcagcccg cattctgttt tttcctggtg
    27001 ggcccacctt cccgctctta aattgccgct gtctgtcacg ggaagcgtac acacctcaca
    27061 gccgatgctc ggataatctt gatcatgaag cttgtgatac gtcagctgat tcagcttaat
    27121 gtaagtccag acatcctccc atgtccagtg aataaggggg cagattttaa tcagtttaaa
    27181 attgtcgtcc ttgttgatat atcggacatg tttccgtgtt tccgactgct cccgcctcag
    27241 cccggtaatc caggcttcca tgcctgacag atcctccctg agcggctcga ttttgcgaag
    27301 gcggcagcac tggtccggct ggcgcttcca aagttcgctg ccatagcgtt tttcctgctc
    27361 ttcaagtgag aggccgggtt ttaaaaagtg gatcgacaga ccgggatagc gatctttcac
    27421 ttcattgatc agctcatatg tttccggaaa atgcagtcct gtatctaaaa acacgatgtc
    27481 cgcttctttc acaacctttg aaatcaagtc gatcaaaacg attccttccg cgccgaagct
    27541 gcaggcgtaa acgatttttt gatacgtgct gtacgcccat ttcaaaacgt ccatctcgcc
    27601 gctgaaagta tccatcacct cttcagaagc tttttcatcc catgtgctat acgttaaaac
    27661 atcgttcatc gattttcccc caatacgtcc taaaggtttg ttttcttatc ctctgatacg
    27721 aaacatgaac taaaagaaca tataggcaga ttattcactt tttagactaa atgtgatctg
    27781 gaaaatgtta ttatttcagc aattttgtga atatccgaaa gaccagatgc gcaagatcga
    27841 aatcaatcat attctctgct tgtggaccta aattaataga gcccaatttg atataccgaa
    27901 atattatcag atgttaagca agtatttcgc aatctgtcat ggagaacaag tgaggaacca
    27961 tatgaaagga cggcgaatat acttactttg acttcacaaa atggatagat acctagtgat
    28021 aagcaagtca ggcgataagg ggctaacatg ctgcctaatg gggaggtggg cgaagatcac
    28081 tccttgccga acggcaacac atgaatgaga aaaacgataa acggggaaag tgaattctta
    28141 tcgtgacagc tgaataatgg ccaacagaca tttacctgaa agcaagaaag atacagtaga
    28201 ttgtgagggg taatcaatga tttcttctga actgatactg cccgacaggc agcttaaacc
    28261 aagaaagaaa gggatcacca tcctgatcga taacggggtt cccttgagct tttttaaaga
    28321 tacgattcac ggagcggcag attatataga ttttgtgaaa tttggatggg gaacgtcttt
    28381 gattacgaaa tatttggagg aaaaaatcga tagtcttagg cagaatgacg ttcaattctt
    28441 ttttggggga acgttgtttg agaagttttt aagccaggat aaaattgaag attactaccg
    28501 ctactgcaaa ttata
//
