LOCUS       NZ_LQYL01000026        25539 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Bacillus licheniformis strain B4090_201601 NODE_53, whole genome
            shotgun sequence.
ACCESSION   NZ_LQYL01000026
VERSION     NZ_LQYL01000026.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus licheniformis
  ORGANISM  Bacillus licheniformis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 209935)
  AUTHORS   Krawczyk,A.O., de Jong,A., Holsappel,S., Eijlander,R.T., van
            Heel,A., Berendsen,E.M., Wells-Bennik,M.H. and Kuipers,O.P.
  TITLE     Genome Sequences of 12 Spore-Forming Bacillus Species, Comprising
            Bacillus coagulans, Bacillus licheniformis, Bacillus
            amyloliquefaciens, Bacillus sporothermodurans, and Bacillus
            vallismortis, Isolated from Foods
  JOURNAL   Genome Announc 4 (3), e00103-16 (2016)
   PUBMED   27174261
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 209935)
  AUTHORS   Berendsen,E.M., Wells-Bennik,M.H., Krawcyk,A.O., De Jong,A.,
            Holsappel,S., Eijlander,R.T. and Kuipers,O.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JAN-2016) Molecular Genetics, University of Groningen,
            Nijenborgh 7, Groningen, Groningen 9747AG, the Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2015
            Assembly Method                   :: Velvet v. 1.2.10
            Assembly Name                     :: B4090
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/26/2024 01:23:23
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,545
            CDSs (total)                      :: 4,463
            Genes (coding)                    :: 4,342
            CDSs (with protein)               :: 4,342
            Genes (RNA)                       :: 82
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 121
            CDSs (without protein)            :: 121
            Pseudo Genes (ambiguous residues) :: 0 of 121
            Pseudo Genes (frameshifted)       :: 68 of 121
            Pseudo Genes (incomplete)         :: 58 of 121
            Pseudo Genes (internal stop)      :: 20 of 121
            Pseudo Genes (multiple problems)  :: 22 of 121
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:24:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 25539
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LQYL01000026.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25539
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..25539
                     /SMILES="NC(C(C)CC)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25539
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1690:5539](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1691..5539
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            <1..1633
                     /locus_tag="B4090_RS10115"
                     /old_locus_tag="B4090_0460"
     CDS             <3..1633
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: PCP (0-64). E-value: 4.9e-26. Score:
                     82.7. Matches aSDomain: nrpspksdomains_B4090_RS10115_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (75-375). E-value:
                     1.2e-171. Score: 564.3. Matches aSDomain:
                     nrpspksdomains_B4090_RS10115_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (383-533). E-value: 4.5e-52.
                     Score: 167.9. Matches aSDomain:
                     nrpspksdomains_B4090_RS10115_TIGR01720.1"
                     /codon_start=2
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020450106.1"
                     /locus_tag="B4090_RS10115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0460"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_235598185.1"
                     /sec_met_domain="PP-binding (E-value: 3.9e-18, bitscore:
                     59.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.1e-81, bitscore:
                     267.8, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LADIWQDVLGIDRIGVTDNFFALGGDSIKGIQMASRLQQHGWKLE
                     MKDLFQHPTIGELSSYVQAADAKPIDQGPVEGEVTLTPIQRWFFERKFTNEHHWNQSVM
                     LHAPSGFDPELVEQTLAALTEHHDALRMVYQKNNGRLIQYNRGPDDRSFAFRVVDLRYV
                     TDIETEIAAQANRLQASLDLENGPLVKAEQYQTAEGDHLLIVIHHLVIDGVSWRILLED
                     FASGYSQAAQQHDVVFPDKTNSFKDWAEALEAYAQTERFLKTADYWRRLEQERICELPK
                     DRAAAERKAENTSAVKFELSEAETRLLLTKVHEPYGTDINDILLSALSLTIREWTNGSN
                     ICINMEGHGREEIIPGMNISRTTGWFTAQYPVVLKSQAAAGLPETIKNVKETLRRIPDK
                     GIGYGILRYLTDRKKAGAIFSIKPDISFNYLGQIDREVQTGFFGPSPYDMGRQVSERSE
                     ALYALSFSGIISKEKFILSCSFNTEEYDRQTIQELMDRFKAFLTALIDHCTAKEEREFT
                     PSDFSAGDLEMEEMGDLFDVLEENLK"
     aSDomain        5..196
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B4090_RS10115_PCP.1"
                     /evalue="4.90E-26"
                     /label="B4090_RS10115_PCP.1"
                     /locus_tag="B4090_RS10115"
                     /protein_end="64"
                     /protein_start="0"
                     /score="82.7"
                     /tool="antismash"
                     /translation="LADIWQDVLGIDRIGVTDNFFALGGDSIKGIQMASRLQQHGWKLE
                     MKDLFQHPTIGELSSYVQA"
     aSModule        5..1603
                     /domains="nrpspksdomains_B4090_RS10115_PCP.1"
                     /domains="nrpspksdomains_B4090_RS10115_Epimerization.1"
                     /domains="nrpspksdomains_B4090_RS10115_TIGR01720.1"
                     /incomplete
                     /locus_tags="B4090_RS10115"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        230..1129
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B4090_RS10115_Epimerization.1"
                     /evalue="1.20E-171"
                     /label="B4090_RS10115_Epimerization.1"
                     /locus_tag="B4090_RS10115"
                     /protein_end="375"
                     /protein_start="75"
                     /score="564.3"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVIDG"
                     /tool="antismash"
                     /translation="EGEVTLTPIQRWFFERKFTNEHHWNQSVMLHAPSGFDPELVEQTL
                     AALTEHHDALRMVYQKNNGRLIQYNRGPDDRSFAFRVVDLRYVTDIETEIAAQANRLQA
                     SLDLENGPLVKAEQYQTAEGDHLLIVIHHLVIDGVSWRILLEDFASGYSQAAQQHDVVF
                     PDKTNSFKDWAEALEAYAQTERFLKTADYWRRLEQERICELPKDRAAAERKAENTSAVK
                     FELSEAETRLLLTKVHEPYGTDINDILLSALSLTIREWTNGSNICINMEGHGREEIIPG
                     MNISRTTGWFTAQYPVVLK"
     CDS_motif       245..274
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS10115_0001"
                     /evalue="3.30E-05"
                     /label="NRPS-E1"
                     /locus_tag="B4090_RS10115"
                     /protein_end="90"
                     /protein_start="80"
                     /score="16.5"
                     /tool="antismash"
                     /translation="LTPIQRWFFE"
     CDS_motif       335..406
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS10115_0002"
                     /evalue="1.20E-04"
                     /label="C2_LCL_024-062"
                     /locus_tag="B4090_RS10115"
                     /protein_end="134"
                     /protein_start="110"
                     /score="14.5"
                     /tool="antismash"
                     /translation="FDPELVEQTLAALTEHHDALRMVY"
     CDS_motif       608..673
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS10115_0003"
                     /evalue="3.30E-12"
                     /label="NRPS-E2"
                     /locus_tag="B4090_RS10115"
                     /protein_end="223"
                     /protein_start="201"
                     /score="38.4"
                     /tool="antismash"
                     /translation="LLIVIHHLVIDGVSWRILLEDF"
     CDS_motif       1076..1126
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS10115_0004"
                     /evalue="2.20E-07"
                     /label="NRPS-E5"
                     /locus_tag="B4090_RS10115"
                     /protein_end="374"
                     /protein_start="357"
                     /score="23.1"
                     /tool="antismash"
                     /translation="NISRTTGWFTAQYPVVL"
     aSDomain        1154..1603
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B4090_RS10115_TIGR01720.1"
                     /evalue="4.50E-52"
                     /label="B4090_RS10115_TIGR01720.1"
                     /locus_tag="B4090_RS10115"
                     /protein_end="533"
                     /protein_start="383"
                     /score="167.9"
                     /tool="antismash"
                     /translation="ETIKNVKETLRRIPDKGIGYGILRYLTDRKKAGAIFSIKPDISFN
                     YLGQIDREVQTGFFGPSPYDMGRQVSERSEALYALSFSGIISKEKFILSCSFNTEEYDR
                     QTIQELMDRFKAFLTALIDHCTAKEEREFTPSDFSAGDLEMEEMGD"
     CDS_motif       1169..1231
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS10115_0005"
                     /evalue="4.70E-13"
                     /label="NRPS-E6"
                     /locus_tag="B4090_RS10115"
                     /protein_end="409"
                     /protein_start="388"
                     /score="41.0"
                     /tool="antismash"
                     /translation="VKETLRRIPDKGIGYGILRYL"
     aSDomain        1691..1786
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B4090_RS10120_NRPS-COM_Nterm.1"
                     /evalue="1.20E-18"
                     /label="B4090_RS10120_NRPS-COM_Nterm.1"
                     /locus_tag="B4090_RS10120"
                     /protein_end="32"
                     /protein_start="0"
                     /score="58.0"
                     /tool="antismash"
                     /translation="MSQFKKEHVQDIYYLSPMQEGMLFHTLLHPGQ"
     gene            1691..5539
                     /gene="licC"
                     /locus_tag="B4090_RS10120"
                     /old_locus_tag="B4090_0461"
     CDS             1691..5539
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-32). E-value: 1.2e-18.
                     Score: 58.0. Matches aSDomain:
                     nrpspksdomains_B4090_RS10120_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (9-308). E-value:
                     5.7e-119. Score: 388.6. Matches aSDomain:
                     nrpspksdomains_B4090_RS10120_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (472-870). E-value: 3e-114.
                     Score: 373.7. Matches aSDomain:
                     nrpspksdomains_B4090_RS10120_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (978-1047). E-value: 3.5e-24. Score:
                     76.8. Matches aSDomain: nrpspksdomains_B4090_RS10120_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1063-1231). E-value:
                     4.5e-28. Score: 91.2. Matches aSDomain:
                     nrpspksdomains_B4090_RS10120_Thioesterase.1"
                     /codon_start=1
                     /gene="licC"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020450107.1"
                     /locus_tag="B4090_RS10120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0461"
                     /product="lichenysin non-ribosomal peptide synthetase LicC"
                     /protein_id="WP_003178834.1"
                     /sec_met_domain="Condensation (E-value: 2.4e-87, bitscore:
                     286.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.3e-127, bitscore:
                     417.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9e-16, bitscore:
                     51.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 6e-26, bitscore:
                     85.6, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQFKKEHVQDIYYLSPMQEGMLFHTLLHPGQGFYIEQISMQVKG
                     SFQKDVLEKSMNVIIGRYDIFRTVFVHEKMKRPVQVVLKERSFQAEEIDLSGLSEAEQN
                     ERIEDYKRKDKEKGFNLSKDIPMRTAVFKKGQDRYEWVWSYHHILLDGWCFGIVVQELF
                     EVYNALRENRPYSLGPVRPYKEYIKWLESQDKQKSLVYWEHHLAGFEGQTTFSEQRKNP
                     EQAGNQPEELLFTLPKEDTEAFTQLAKAHHTTLSTALQAVWSVLLSRYQRSRDLIFGTV
                     VSGRPADIQGVEHMVGLFINVVPKRATFGPQTTFTELVADLQKQALEAEPHQYVPLYEI
                     QSHIAAPNLIDHIIVFENYPLQEANKQQKEKNLGFTMDEISVFEKSNYDLNLLASPGEE
                     MMLKLAYNRNIFEPSFILRLKEQLLTAIREVIRDPEQPLDDICVVSKKEKERLLHEFNG
                     QVQRKQIGLTIPQWFEQYAEALPEKPAVSAAGRTLTYRELNEKANKVAHLLRKKNVGRG
                     EPVALLFRRSPEMVIAILAVLKAGGAYLPIDPEYPEARIQYMLEDSGAVCMLTQEELAG
                     RAASLSFHKHTILIDDPAVSAESGRNLEIAAEPDDLAYIMYTSGTTGKPKGNLTTHANI
                     TRVVKETNYISLSEKDTLLSLSNYAFDGFTFDLYGALLNGAKLVVADQATILHIGKLTE
                     AIQKENITVMFVTTALFNLLVDAGTGWMKGIRKVLFGGERSSVSHVKKAFAAMGPDRII
                     HVYGPTETTVFATFYPVNRMEDSAVSIPIGKPINETNAYILTENNRLQPIGAVGELCLS
                     GTGVSRGYLNRPELTAEKFAPHPFNSGETMYRTGDLARWLPDGNIDFIGRIDDQVKIRG
                     HRIELGEIEEQLMRCQGVKEAVVTARKSGNGDAALTAYVVPVQGTEVANEEVRRQLARR
                     LPAYMVPAAYIMLEELPLTANGKVNRRLLPEADGRPNSTERRAPRNATEEKLAVIWSEV
                     LGRQQIGIDENFFEIGGHSLKAMAVASRMLKDLAIDVPVNVLFEMPTIEGLAAYIDQGG
                     HVDEVKKTVFNQASTRHLFAFPPVLGYGIMYGKLAEQMPEYRIHAFDFIESDDRAVRYA
                     EAISDLQPEGPLTLIGYSAGCGLAFEVAQALEKNGRKVEKLLMIDSYMKNDVSDLEGRS
                     IEADTAALMEANKDNEYMKIKTVADGIAKKMTAYYSYFVNLVHQGTVSSEIHLIKSEHA
                     KPLPAWLSLWKEGTESSYDEYQGAGRHDEMLADGFVKSNADLIRQILGERAAVIGGA"
     aSDomain        1718..2614
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B4090_RS10120_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="5.70E-119"
                     /label="B4090_RS10120_Condensation_DCL.1"
                     /locus_tag="B4090_RS10120"
                     /protein_end="308"
                     /protein_start="9"
                     /score="388.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILLDG"
                     /tool="antismash"
                     /translation="QDIYYLSPMQEGMLFHTLLHPGQGFYIEQISMQVKGSFQKDVLEK
                     SMNVIIGRYDIFRTVFVHEKMKRPVQVVLKERSFQAEEIDLSGLSEAEQNERIEDYKRK
                     DKEKGFNLSKDIPMRTAVFKKGQDRYEWVWSYHHILLDGWCFGIVVQELFEVYNALREN
                     RPYSLGPVRPYKEYIKWLESQDKQKSLVYWEHHLAGFEGQTTFSEQRKNPEQAGNQPEE
                     LLFTLPKEDTEAFTQLAKAHHTTLSTALQAVWSVLLSRYQRSRDLIFGTVVSGRPADIQ
                     GVEHMVGLFINVVPKRAT"
     aSModule        1718..5383
                     /complete
                     /domains="nrpspksdomains_B4090_RS10120_Condensation_DCL.1"
                     /domains="nrpspksdomains_B4090_RS10120_AMP-binding.1"
                     /domains="nrpspksdomains_B4090_RS10120_PCP.1"
                     /domains="nrpspksdomains_B4090_RS10120_Thioesterase.1"
                     /final_module
                     /locus_tags="B4090_RS10120"
                     /monomer_pairings="Ile -> Ile"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       1727..1768
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS10120_0001"
                     /evalue="3.00E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="B4090_RS10120"
                     /protein_end="26"
                     /protein_start="12"
                     /score="15.8"
                     /tool="antismash"
                     /translation="YYLSPMQEGMLFHT"
     CDS_motif       1787..1906
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS10120_0002"
                     /evalue="1.10E-11"
                     /label="C2_DCL_024-062"
                     /locus_tag="B4090_RS10120"
                     /protein_end="72"
                     /protein_start="32"
                     /score="37.0"
                     /tool="antismash"
                     /translation="GFYIEQISMQVKGSFQKDVLEKSMNVIIGRYDIFRTVFVH"
     CDS_motif       2123..2188
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS10120_0003"
                     /evalue="3.40E-12"
                     /label="C3_DCL_135-156"
                     /locus_tag="B4090_RS10120"
                     /protein_end="166"
                     /protein_start="144"
                     /score="38.7"
                     /tool="antismash"
                     /translation="YHHILLDGWCFGIVVQELFEVY"
     CDS_motif       2234..2272
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS10120_0004"
                     /evalue="2.00E-03"
                     /label="C4_DCL_171-183"
                     /locus_tag="B4090_RS10120"
                     /protein_end="194"
                     /protein_start="181"
                     /score="10.8"
                     /tool="antismash"
                     /translation="PYKEYIKWLESQD"
     CDS_motif       2513..2608
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS10120_0005"
                     /evalue="2.00E-18"
                     /label="C5_DCL_263-294"
                     /locus_tag="B4090_RS10120"
                     /protein_end="306"
                     /protein_start="274"
                     /score="58.8"
                     /tool="antismash"
                     /translation="DLIFGTVVSGRPADIQGVEHMVGLFINVVPKR"
     CDS_motif       2657..2770
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS10120_0006"
                     /evalue="5.60E-18"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="B4090_RS10120"
                     /protein_end="360"
                     /protein_start="322"
                     /score="57.4"
                     /tool="antismash"
                     /translation="QKQALEAEPHQYVPLYEIQSHIAAPNLIDHIIVFENYP"
     aSDomain        3107..4300
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B4090_RS10120_AMP-binding.1"
                     /evalue="3.00E-114"
                     /label="B4090_RS10120_AMP-binding.1"
                     /locus_tag="B4090_RS10120"
                     /protein_end="870"
                     /protein_start="472"
                     /score="373.7"
                     /specificity="substrate consensus: Ile"
                     /tool="antismash"
                     /translation="FEQYAEALPEKPAVSAAGRTLTYRELNEKANKVAHLLRKKNVGRG
                     EPVALLFRRSPEMVIAILAVLKAGGAYLPIDPEYPEARIQYMLEDSGAVCMLTQEELAG
                     RAASLSFHKHTILIDDPAVSAESGRNLEIAAEPDDLAYIMYTSGTTGKPKGNLTTHANI
                     TRVVKETNYISLSEKDTLLSLSNYAFDGFTFDLYGALLNGAKLVVADQATILHIGKLTE
                     AIQKENITVMFVTTALFNLLVDAGTGWMKGIRKVLFGGERSSVSHVKKAFAAMGPDRII
                     HVYGPTETTVFATFYPVNRMEDSAVSIPIGKPINETNAYILTENNRLQPIGAVGELCLS
                     GTGVSRGYLNRPELTAEKFAPHPFNSGETMYRTGDLARWLPDGNIDFIGRIDDQVKIR"
     CDS_motif       3293..3334
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS10120_0007"
                     /evalue="1.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="B4090_RS10120"
                     /protein_end="548"
                     /protein_start="534"
                     /score="18.6"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPID"
     CDS_motif       3527..3586
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS10120_0008"
                     /evalue="5.50E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="B4090_RS10120"
                     /protein_end="632"
                     /protein_start="612"
                     /score="25.1"
                     /tool="antismash"
                     /translation="AYIMYTSGTTGKPKGNLTTH"
     CDS_motif       4094..4183
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS10120_0009"
                     /evalue="1.40E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="B4090_RS10120"
                     /protein_end="831"
                     /protein_start="801"
                     /score="55.7"
                     /tool="antismash"
                     /translation="PIGAVGELCLSGTGVSRGYLNRPELTAEKF"
     CDS_motif       4265..4330
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS10120_0010"
                     /evalue="9.70E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="B4090_RS10120"
                     /protein_end="880"
                     /protein_start="858"
                     /score="39.9"
                     /tool="antismash"
                     /translation="FIGRIDDQVKIRGHRIELGEIE"
     aSDomain        4625..4831
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B4090_RS10120_PCP.1"
                     /evalue="3.50E-24"
                     /label="B4090_RS10120_PCP.1"
                     /locus_tag="B4090_RS10120"
                     /protein_end="1047"
                     /protein_start="978"
                     /score="76.8"
                     /tool="antismash"
                     /translation="EEKLAVIWSEVLGRQQIGIDENFFEIGGHSLKAMAVASRMLKDLA
                     IDVPVNVLFEMPTIEGLAAYIDQG"
     aSDomain        4880..5383
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B4090_RS10120_Thioesterase.1"
                     /evalue="4.50E-28"
                     /label="B4090_RS10120_Thioesterase.1"
                     /locus_tag="B4090_RS10120"
                     /protein_end="1231"
                     /protein_start="1063"
                     /score="91.2"
                     /tool="antismash"
                     /translation="RHLFAFPPVLGYGIMYGKLAEQMPEYRIHAFDFIESDDRAVRYAE
                     AISDLQPEGPLTLIGYSAGCGLAFEVAQALEKNGRKVEKLLMIDSYMKNDVSDLEGRSI
                     EADTAALMEANKDNEYMKIKTVADGIAKKMTAYYSYFVNLVHQGTVSSEIHLIKSEHAK
                     PLPAW"
     CDS_motif       5030..5104
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS10120_0011"
                     /evalue="2.60E-10"
                     /label="NRPS-te1"
                     /locus_tag="B4090_RS10120"
                     /protein_end="1138"
                     /protein_start="1113"
                     /score="32.7"
                     /tool="antismash"
                     /translation="QPEGPLTLIGYSAGCGLAFEVAQAL"
     gene            5543..6283
                     /gene="licTE"
                     /locus_tag="B4090_RS10125"
                     /old_locus_tag="B4090_0462"
     CDS             5543..6283
                     /NRPS_PKS="Domain: Thioesterase (15-230). E-value: 1.8e-48.
                     Score: 157.9. Matches aSDomain:
                     nrpspksdomains_B4090_RS10125_Thioesterase.1"
                     /codon_start=1
                     /gene="licTE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_043926232.1"
                     /locus_tag="B4090_RS10125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0462"
                     /product="lichenysin biosynthesis thioesterase LicTE"
                     /protein_id="WP_061576563.1"
                     /sec_met_domain="Thioesterase (E-value: 7.6e-59, bitscore:
                     193.2, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 9e-08, bitscore: 25.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.6e-13, bitscore:
                     43.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEIIKQFGAPASGMQLICFPFAGGYSASFRPLHEHLKTDFDMLA
                     IEPPGHGTNRMALVDNLEKLADLYIAALKPRLSSQFVLFGHSMGGMVVYRLAQKLEQEG
                     IFAAAAVISAIQPPHIQRQKVSHQKDSAFLDHLIQLGGIPKELAEHREMMNFFLPSFRA
                     DYRALETFCHTDHTPLRSPVHILNGDRDEKCMRDALGWKKWANTIDFHYFKGGHMYLLS
                     ETEQVAAKLKTIAAASRSTAVPTM"
     aSDomain        5588..6232
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B4090_RS10125_Thioesterase.1"
                     /evalue="1.80E-48"
                     /label="B4090_RS10125_Thioesterase.1"
                     /locus_tag="B4090_RS10125"
                     /protein_end="230"
                     /protein_start="15"
                     /score="157.9"
                     /tool="antismash"
                     /translation="QLICFPFAGGYSASFRPLHEHLKTDFDMLAIEPPGHGTNRMALVD
                     NLEKLADLYIAALKPRLSSQFVLFGHSMGGMVVYRLAQKLEQEGIFAAAAVISAIQPPH
                     IQRQKVSHQKDSAFLDHLIQLGGIPKELAEHREMMNFFLPSFRADYRALETFCHTDHTP
                     LRSPVHILNGDRDEKCMRDALGWKKWANTIDFHYFKGGHMYLLSETEQVAAK"
     CDS_motif       5783..5842
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B4090_RS10125_0001"
                     /evalue="5.70E-06"
                     /label="NRPS-te1"
                     /locus_tag="B4090_RS10125"
                     /protein_end="100"
                     /protein_start="80"
                     /score="18.9"
                     /tool="antismash"
                     /translation="FVLFGHSMGGMVVYRLAQKL"
     gene            complement(6330..7241)
                     /locus_tag="B4090_RS10130"
                     /old_locus_tag="B4090_0463"
     CDS             complement(6330..7241)
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178840.1"
                     /locus_tag="B4090_RS10130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0463"
                     /product="DMT family transporter"
                     /protein_id="WP_003178840.1"
                     /transl_table=11
                     /translation="MNKSAYAAALLYAFIIGFSFFFVKLALTAASPVDILAHRFTVAFL
                     AALIPLLLGWVKIAISIKDALKVLPLALFYPVMFFAFQVFGLVYTSSSEAGIIQAAIPI
                     FTMIFAAYFLNERFTKRQFFFTVLSAAGVACIFMMKSAGTGSSDLRGAALILLSALSSA
                     GYSVLARKMTRTFSSLELTYVTTGAGFLFFNGIAGISHMSDGTLSGFFAPFTDPVFVLS
                     VLYLGVLSSFATSFLSNYALSKIEAAKISMFNHLATLVTILAGIIWLGESLEWFHFAGT
                     GMIIAGIIGATMVRRENRLKKS"
     gene            7377..8705
                     /locus_tag="B4090_RS10135"
                     /old_locus_tag="B4090_0464"
     CDS             7377..8705
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (96-433). E-value:
                     2.7e-24. Score: 77.9. Matches aSDomain:
                     nrpspksdomains_B4090_RS10135_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178841.1"
                     /locus_tag="B4090_RS10135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0464"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_061576564.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8.4e-24, bitscore:
                     78.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHKYVALMNELEDMIEDKSFQEGDRLPSIRALAIRFKVSKSTVIR
                     ALNELERRHLIYSVPKSGYYVVKKTNQRPNSGKAVIDFAASAPDPDVFPYIDFQHCINK
                     AIDTYKNDLFIYGTPTGLPSLIQAVQKELANSQVFAKEEHIFITSGVQQALALLASMPF
                     PNRKRKVLIEQPSYHLLIKYLEVHGIPTVGIDMDELERIFQTEDIKFFYTMPRFHNPLG
                     TSYTEREKTAIVKLAEKYDVYIAEDDFLGDLENDKKADPLHYYDVSSHVIYLKSFSKII
                     FPGLRVGAAVLPDSLTIVFNRYKQLLDIDSSMLSQAALEIYLKSGMFEKHKQKIRSSYQ
                     KRSCLLHDLLKECSASLGDVFEFHPPAQPAIHTHIELDRTIPASRLIKSLQKRDVLLEP
                     VNAHYMPAFPKRNLLKINTSNVKEEDIRSGIERLRQAVETAYF"
     aSDomain        7665..8675
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B4090_RS10135_Aminotran_1_2.1"
                     /evalue="2.70E-24"
                     /label="B4090_RS10135_Aminotran_1_2.1"
                     /locus_tag="B4090_RS10135"
                     /protein_end="433"
                     /protein_start="96"
                     /score="77.9"
                     /tool="antismash"
                     /translation="DFQHCINKAIDTYKNDLFIYGTPTGLPSLIQAVQKELANSQVFAK
                     EEHIFITSGVQQALALLASMPFPNRKRKVLIEQPSYHLLIKYLEVHGIPTVGIDMDELE
                     RIFQTEDIKFFYTMPRFHNPLGTSYTEREKTAIVKLAEKYDVYIAEDDFLGDLENDKKA
                     DPLHYYDVSSHVIYLKSFSKIIFPGLRVGAAVLPDSLTIVFNRYKQLLDIDSSMLSQAA
                     LEIYLKSGMFEKHKQKIRSSYQKRSCLLHDLLKECSASLGDVFEFHPPAQPAIHTHIEL
                     DRTIPASRLIKSLQKRDVLLEPVNAHYMPAFPKRNLLKINTSNVKEEDIRSGIERL"
     gene            complement(8717..9397)
                     /locus_tag="B4090_RS10140"
                     /old_locus_tag="B4090_0465"
     CDS             complement(8717..9397)
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: ACPS (103-166). E-value: 2.1e-20. Score:
                     65.0. Matches aSDomain:
                     nrpspksdomains_B4090_RS10140_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178843.1"
                     /locus_tag="B4090_RS10140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0465"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_003178843.1"
                     /transl_table=11
                     /translation="MKIYAVYMDQLPEAGQFNRMMAMVSEEKRKKVGRYRYPEDASRTL
                     IGEVLARHIISETFHLPNEQIRFTEGRYGKPAAEGLNDFHFNISHSGKWIVCGAGAQPI
                     GVDVEKIKPINFDIAKRFFSPSEHDDLMEKDESERLSYFYHLWTMKESFIKQAGKGLSL
                     PLDSFSVKLNEQGRASVETPPGYPPCYIQAYEIDPGYKMAVCSAAPEFPGRIVMKSCAE
                     LSML"
     aSDomain        complement(8900..9088)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B4090_RS10140_ACPS.1"
                     /evalue="2.10E-20"
                     /label="B4090_RS10140_ACPS.1"
                     /locus_tag="B4090_RS10140"
                     /protein_end="166"
                     /protein_start="103"
                     /score="65.0"
                     /tool="antismash"
                     /translation="IGVDVEKIKPINFDIAKRFFSPSEHDDLMEKDESERLSYFYHLWT
                     MKESFIKQAGKGLSLPLD"
     gene            9497..10282
                     /locus_tag="B4090_RS10145"
                     /old_locus_tag="B4090_0466"
     CDS             9497..10282
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1098: enterobactin/ferric enterobactin esterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009330220.1"
                     /locus_tag="B4090_RS10145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0466"
                     /product="alpha/beta hydrolase-fold protein"
                     /protein_id="WP_009330220.1"
                     /transl_table=11
                     /translation="MIDGTLIKDTCFGRELLIYLPPSYGSGENRYPVLYVHDLGDLFDP
                     AYSNSLRSIEKLFSSQEVPELLLVGVAPKDRESEYTPFPKRHLLPNKREYGGKGNEYAA
                     FLANRLKPHIDRHYRTNPSREQTGIIGKSFGGLISVYTAFLASETFGKIGSLSGSFWFE
                     GITEFMKNNRFENKHLRIYMDVGSTEGTDRDNLQKEMIPRTKEAFSLLTESAASEKELK
                     FVIDEGGSHRLERFAKRFPEAVKWLFGSCHNSARNGRSF"
     gene            10528..10911
                     /locus_tag="B4090_RS10150"
                     /old_locus_tag="B4090_0467"
     CDS             10528..10911
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178845.1"
                     /locus_tag="B4090_RS10150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0467"
                     /product="GyrI-like domain-containing protein"
                     /protein_id="WP_003178845.1"
                     /transl_table=11
                     /translation="MVDAAFKYGYSTPESLSGGLQPPSRHQPFTGPRKRRTLRAFPRLS
                     FHIQIKGVEDMDYKIVEKEPFQVIGKALEVTVKDGQNKKDIPAFWNELNHNGFTDSLKP
                     HIGPLGFLGVCMDFNDQPDTFNF"
     assembly_gap    10963..11035
                     /estimated_length=73
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            11041..11322
                     /locus_tag="B4090_RS22430"
     CDS             11041..11322
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018184.4"
                     /locus_tag="B4090_RS22430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GyrI-like domain-containing protein"
                     /protein_id="WP_081106704.1"
                     /transl_table=11
                     /translation="MGPVNPAGQATWERIFSECFPATGYELANEPQFEAYPEDGDIMAQ
                     DHITEIWIPVVSRNNPEREKRMKRSSVFFQRHMYRLGSSDAPSCHCCF"
     gene            complement(11248..11910)
                     /locus_tag="B4090_RS10155"
                     /old_locus_tag="B4090_0468"
     CDS             complement(11248..11910)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178846.1"
                     /locus_tag="B4090_RS10155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0468"
                     /product="YitT family protein"
                     /protein_id="WP_003178846.1"
                     /transl_table=11
                     /translation="MKRELVLRWLFYFVGLIVLSFGVSLTIEGKVLGIGPWDAFHYGLY
                     MLLGLTVGQWAIIVGAVIVGLTSLFTKAWPKIGAVLNMLLIGIFIDFFTYILPDPETYI
                     SSTVVFVIGVIFIGYGVGIYVSADLGAGPRDSLMLLISEKTGWNVQWVRNGMELTILLI
                     GWLLGGPIGIGTVLTAILTGLILRFSLPQSKQLLKAAMAGRRIRAAKPVHMSLKKNG"
     misc_feature    11921..11934
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.31"
                     /tool="antismash"
     gene            12166..12696
                     /locus_tag="B4090_RS10160"
     CDS             12166..12696
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178848.1"
                     /locus_tag="B4090_RS10160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_003178848.1"
                     /transl_table=11
                     /translation="MKKLYISAVLGLLFVFVGGTKIHAQEPQNNNGVLDENKFIDETVY
                     SYTQPISIQDGEVTTQAKKYIKTVSVNRSYKSLLNIVVARHYSDTTFTYGSGKLYKSPR
                     ALSNDWWTLPPNFKSGSSKSWDWYNTGKGATGRSNLQVRYTWGVPTPWGPVGSNYSSRI
                     KVSFKSNGSWYTN"
     gene            12723..13652
                     /locus_tag="B4090_RS10165"
                     /old_locus_tag="B4090_0469"
     CDS             12723..13652
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016886450.1"
                     /locus_tag="B4090_RS10165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0469"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_061576565.1"
                     /transl_table=11
                     /translation="MGTIGINFKNIQHQYRTKDVLRGVSFHADPSSITFLAGENGAGKT
                     TLIKVALGLISPKAGNALFDGQSVGEIREKISCVFDEPPVYPNESGLDNLKFLSGIHSL
                     DRKWSQEVCAMLKLDEGLLKQKAKALSLGQRHRLAVAAALLRKPKYLFLDEPSIGLDPP
                     SWQLVQIALKQMTARGCAILITGQNYDAIENLADNIAILQSGKIIFSGPIVKLVQAFPV
                     YVRIVTDDHREIAVQFPEAEPDSSGIYRIVCESGEQARAVINQVRRSTLNFQELSTEKA
                     SMGKMVTDIYKDGFQSEKRGLTYESVQN"
     gene            13633..14532
                     /locus_tag="B4090_RS10170"
                     /old_locus_tag="B4090_0470"
     CDS             13633..14532
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /function="Molecular Function: transcription factor
                     activity, Cellular Component: intracellular, Biological
                     Process: regulation of transcription, DNA-dependent"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011197538.1"
                     /locus_tag="B4090_RS10170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0470"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_011197538.1"
                     /transl_table=11
                     /translation="MNPFKIETNQLKNSMLVRVCIALLFCCFIWGLLTLYQSAEGEERR
                     QEKIHQSVIDEVKKNGAEEELENGGLEIEKNDDIARSMYIGLHPSVTPNLFLLILANIG
                     PIVFIIIGSHLVGSEYHQGTVKMKAAHIGWRKAVSGKLCALLSLVIVMVIAALLLGLAG
                     GWLAWTFATAHSDLAASLEVNAAVSYPILILFLMIGLTFYSVLGMTVTLLTKSRLAGVL
                     ISLAIPYAEQMMSLPFLPLTAYQSLMVHHFIYVDGSIIGQPYLTEPMGEPGAWAVLVCW
                     LFVVIAVQQFAAKKQQIL"
     gene            14545..14724
                     /locus_tag="B4090_RS23010"
                     /old_locus_tag="B4090_0471"
     CDS             14545..14724
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178855.1"
                     /locus_tag="B4090_RS23010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0471"
                     /product="hypothetical protein"
                     /protein_id="WP_009330211.1"
                     /transl_table=11
                     /translation="MALIFLVRLICLAFLACLALLFYAPFLAMPVWIALIIALIVCLYL
                     AFIEEMKEWRRRKH"
     gene            complement(14765..14947)
                     /locus_tag="B4090_RS10175"
                     /old_locus_tag="B4090_0472"
     CDS             complement(14765..14947)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178857.1"
                     /locus_tag="B4090_RS10175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0472"
                     /product="hypothetical protein"
                     /protein_id="WP_003178857.1"
                     /transl_table=11
                     /translation="MRMVLNVVGLFAFIGMTVGAYTQAYYLDEHLELLRFAYMTALEWK
                     EFFCLCPGRPSSISF"
     misc_feature    complement(14930..14948)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.87"
                     /tool="antismash"
     misc_feature    14950..14964
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.26"
                     /tool="antismash"
     misc_feature    15061..15078
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.15"
                     /tool="antismash"
     misc_feature    complement(15181..15192)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.67"
                     /tool="antismash"
     gene            15226..16887
                     /locus_tag="B4090_RS10180"
                     /old_locus_tag="B4090_0473"
     CDS             15226..16887
                     /GO_function="GO:0016830 - carbon-carbon lyase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178859.1"
                     /locus_tag="B4090_RS10180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0473"
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="WP_003178859.1"
                     /transl_table=11
                     /translation="MQQRNTPDVQRWFPSEDGNEAKRNEFLSLIEQLIEGVDNLKNPDQ
                     VNLGGEKNREGFFYEKLVAESRIPHEGAPMKEVNEELLKLLHGHPYHTKYFFTNILPMA
                     SIPGILGMLTAFMVNGNNLWDVYGPAGAEAEVKVTAMMSKLAGYDAETSGGYTTWGGQG
                     AVYSGLRIAIAKMAPSSLKEGVPGNFYAFCSEAAHYSLYKSMEAAGLGSDHLIKVKTNL
                     DHSMDTEDLREKLRQVCEAGGIPVYIVATTGTTDAIGIDDVSAVRRAAEETAKSFGLPV
                     PHIHADSALGGFFAFFNEYDLNENALSFSPGVLSMIKPIQEKMRHLHAADSLCFDFQKL
                     GQTPYVTSLFLVKDRNDLKRIDLDPDETPYVGHRGYGDYHTGYTLECSRMASSISMYSA
                     LMAFGYEGYQKLLAQFLEVNLHFREQLSRQIPEADIVNPDNCGMSTLFRIYPEGAPRFE
                     DEISGACTIEELERNNALTEKLFEKLGTKRDKMFFGDTKKHLLVKSCEGVELPLCVSKF
                     FVISPYTMPEHVPGIIDYLKETIEEVFREHGSLMTN"
     gene            16902..18626
                     /locus_tag="B4090_RS10185"
                     /old_locus_tag="B4090_0474"
     CDS             16902..18626
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178861.1"
                     /locus_tag="B4090_RS10185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0474"
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_061576566.1"
                     /transl_table=11
                     /translation="MKTFKKKLTEHISVKIMIGVALVLLITIASFSAVFTFISKDLSEQ
                     LKQQFQNRLYTDIHLAENQIKRLDGNPLEIDSADGPLYKQTKMAVDSLKKKNKLENIYI
                     LSNEGGKERILVLSDTPDDFGTDYSFSPEMKEALTTNKETVSDVYEDEYGIHQSIFLPL
                     ENGSGEKVGILGIDLDASVIPETAAKAKWYTIAISAFVLLLGMVMAYFLGSYIAKPIRQ
                     LMKASEKIADGDLSADISVKSRDEAGKLAESFKRMSENLQQLIGHISASSEEVSKTSLQ
                     LKNVSAESSESAAQVAESMNSMSEGINEVVSSVSDCHTSAAEIDQQLTHVTEKVNEMKN
                     VAEGVSKDSKTGQELVEETLRQTQTIKNVMEESKQAASEMQNHTEEIEKVIGMISSIAE
                     QTNLLALNASIEAARVGEEGQGFAVVAGEVRKLSERSADAALSVSQLVAGTQESSRLVM
                     ERIQEGNEAVDKGQILINGTYENFSGIFKGISQFAERTDQLLQSLLKVEKSYQTISSAM
                     EQISAVTEEQAAGSEEVAAAAEQQSAGMQEIASAIQQLSALSEELNQAASKFKLAAE"
     misc_feature    16904..16915
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.4"
                     /tool="antismash"
     gene            complement(18665..19408)
                     /locus_tag="B4090_RS10190"
                     /old_locus_tag="B4090_0475"
     CDS             complement(18665..19408)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388241.2"
                     /locus_tag="B4090_RS10190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0475"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_061576567.1"
                     /transl_table=11
                     /translation="MLAIKGLNKSFGENEILKKIDLNIEKGKVIAILGPSGSGKTTLLR
                     CLNALEIPNRGILSFDDFTIDFSKKNKPADLLRLRRKSGMVFQAYHLFPHRTVLENVME
                     GPVKVQKRNKEEVKKEAVQLLQKVGLEDKMDLYPFQLSGGQQQRVGIARALAIKPELML
                     FDEPTSALDPELVGEVLKVMKDLANEGWTMVVVTHEIKFAQDVADEVVFIDGGVIVEQG
                     PPEQIFSAPKEERTKKFLNRILNPV"
     gene            complement(19424..20128)
                     /locus_tag="B4090_RS10195"
                     /old_locus_tag="B4090_0476"
     CDS             complement(19424..20128)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388242.1"
                     /locus_tag="B4090_RS10195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0476"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_061576610.1"
                     /transl_table=11
                     /translation="MFLSNIQAAAISQAIPWDLVRESFWPIFLRGIYYSIPLAILSFIF
                     GMIIALITALARMSKSRILRAVFGIYVSAIRGTPLLVQLFIIFYLFPAFQVTIDPFPSA
                     IIAFSLNVGAYASEIIRASILSVPKGQWEAAYSIGMTQKTALTRVILPQAVRVSIPPLS
                     NTFISLVKDTSLASQILVAELFRKAQEIGAGNLDQILIIYMEAAFIYWIICFVLALVQQ
                     QIERRLDRYVAK"
     gene            complement(20115..20921)
                     /gene="tcyA"
                     /locus_tag="B4090_RS10200"
                     /old_locus_tag="B4090_0477"
     CDS             complement(20115..20921)
                     /codon_start=1
                     /gene="tcyA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388243.2"
                     /locus_tag="B4090_RS10200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0477"
                     /product="cystine ABC transporter substrate-binding
                     lipoprotein TcyA"
                     /protein_id="WP_009330207.1"
                     /transl_table=11
                     /translation="MKKAIFAVLLTLLITVMAACGASGDNSKDKNAAGDSLWSSIKDKG
                     VLTVGTEGTYEPFTFHDKKTDKLTGYDVEVMQEVAKRLNLKAEFKETQWDSMFAGLNSK
                     RFDVVANQVGKKDREDQYDFSDSYTTSQAVVVTKADNNDVKSEGDVKGKKAAQSLTSNY
                     NDLAKNAGAEIEGVEGMAQAFQLIQQGRVDLTYNDKLAVLNYLKTSGNKNLKIAFETGE
                     PQTTHFAFRKGSGELVDKVNSALKDMKEDGTLAKIAKKWFGEDVSK"
     gene            complement(21050..22462)
                     /locus_tag="B4090_RS10205"
                     /old_locus_tag="B4090_0478"
     CDS             complement(21050..22462)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1112: sigma-54
                     dependent trancsriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017473992.1"
                     /locus_tag="B4090_RS10205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0478"
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="WP_003178873.1"
                     /transl_table=11
                     /translation="MLKDYDFLKLIFQGIIDEIDIGLHVVDENGTSVVYNKKMSQIEGM
                     DVGDVLGKNVLDVFTFASQHDSTLLQALHHGKTNKNVKQTYFNNKGQEITTVNHTFPIM
                     ENGNTKGAVEIAKDVTKLERLIRENMNKTESTKYTFDSLIGVSPAFKEVIEHAKRATRT
                     SSSILIVGDTGTGKELFAQSIHNGSQRSTGPFISQNCAALPESLVEGLLFGTVKGAFTG
                     AVDRPGLFEQADGGTLLLDEINSLDFRLQAKLLRAIQEKTIRRIGASKDTPIDVRIIAT
                     MNEDPVDAVSGQRLRKDLYYRLSVVTLFIPPLKDRKEDIMPLTQHFIDKYNALFQMEVK
                     GFEEEVRRFLLSYDWPGNVRELEHLIEGAMNLMSYEDKIELTHLPLQYRTKPAAKEQLP
                     QQGYDLFAPLPSASAAPLKEQIENAEKYYIQKTVKKCNYNVSQAARVLGISRQSLQYRL
                     KKWKIRFDQESE"
     misc_feature    22433..22447
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.67"
                     /tool="antismash"
     misc_feature    22550..22566
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.47"
                     /tool="antismash"
     misc_feature    complement(22590..22604)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 24.36"
                     /tool="antismash"
     misc_feature    22621..22634
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.31"
                     /tool="antismash"
     gene            22704..23906
                     /locus_tag="B4090_RS10210"
                     /old_locus_tag="B4090_0479"
     CDS             22704..23906
                     /GO_function="GO:0004587 - ornithine aminotransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (28-349). E-value: 5.1e-119.
                     Score: 389.2. Matches aSDomain:
                     nrpspksdomains_B4090_RS10210_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178876.1"
                     /locus_tag="B4090_RS10210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0479"
                     /product="ornithine--oxo-acid transaminase"
                     /protein_id="WP_061576568.1"
                     /sec_met_domain="Aminotran_3 (E-value: 6.4e-139, bitscore:
                     456.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVLSKSEKIMKQTAHFGANNYHPLPIVISEAEGAWVKDPEGNRY
                     MDMLSAYSAVNQGHRHPKIIQALKDQADKITLTSRAFHNDQLGPFYEKVASLTGKDMVL
                     PMNTGAEAVESAVKAARRWAYDVKGVPDNQAEIIACEGNFHGRTMLAVSLSSEEEYKRG
                     FGPMLPGIKLIPYGDLEALKQAITPNTAAFLIEPIQGEAGIVIPPEGFLKQAAEVCKER
                     NVLFIADEIQSGLARTGKMFASDWEDVTPDMYILGKALGGGVFPISCIAANRDVLGVFN
                     PGSHGSTFGGNPLACAVSIAALEVLEDERLAERSLELGEYFKEKLSQIDNPKIKEVRGR
                     GLFIGVELTEAARPYCERLKEEGMLCKETHETVIRFAPPLVISHEDLDWAIEKITRVLS
                     K"
     aSDomain        22788..23750
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B4090_RS10210_Aminotran_3.1"
                     /evalue="5.10E-119"
                     /label="B4090_RS10210_Aminotran_3.1"
                     /locus_tag="B4090_RS10210"
                     /protein_end="349"
                     /protein_start="28"
                     /score="389.2"
                     /tool="antismash"
                     /translation="ISEAEGAWVKDPEGNRYMDMLSAYSAVNQGHRHPKIIQALKDQAD
                     KITLTSRAFHNDQLGPFYEKVASLTGKDMVLPMNTGAEAVESAVKAARRWAYDVKGVPD
                     NQAEIIACEGNFHGRTMLAVSLSSEEEYKRGFGPMLPGIKLIPYGDLEALKQAITPNTA
                     AFLIEPIQGEAGIVIPPEGFLKQAAEVCKERNVLFIADEIQSGLARTGKMFASDWEDVT
                     PDMYILGKALGGGVFPISCIAANRDVLGVFNPGSHGSTFGGNPLACAVSIAALEVLEDE
                     RLAERSLELGEYFKEKLSQIDNPKIKEVRGRGLFIGVELT"
     misc_feature    23992..24006
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.7"
                     /tool="antismash"
     gene            24120..25523
                     /locus_tag="B4090_RS10215"
                     /old_locus_tag="B4090_0480"
     CDS             24120..25523
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0003333 - amino acid transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178877.1"
                     /locus_tag="B4090_RS10215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_0480"
                     /product="amino acid permease"
                     /protein_id="WP_009330205.1"
                     /transl_table=11
                     /translation="MKSRHLFMISLGGVIGTGFFLGTGYTINEAGPIGAILSYLAGGMI
                     MYFTMLCLGELAVAMPVSGSFQTYATKFIGPATGFAVGWIYWLGWSVTVALEFLSAGQL
                     MKRWFPDVGVWIWCLIFGLLLFSLNALSAKAFGESEFWLSGIKIIVILLFIILGGGAMF
                     GLIDLKDGQAAPFFSNLIGDGIFPNGFGAIFITMITVNFAFQGTELIGIAAGESENPEK
                     TVPRSIKQTVWRTLVFFGLSVFVLAGLIPWEKAGVVESPFVVVFEQIGIPYAADLMNFV
                     ILIALLSVANSGLYASTRMLYSLAKEGMAAQALSRVNKRGIPMNALWITLGFAGLSLIS
                     SVVAAETLYIWLLSLAGLSAQVGWITITVSQLLFRRRYVKEGGKVEDLKFKTPLYPYLP
                     LTGFILNSAVLVSLAFDSEQRMALYCGILFMSACYFVYHVFVKKRQALDRQEAMIYQNK
                     TNDEVVIDE"
ORIGIN
        1 gttggcggac atttggcagg atgttctcgg catagaccga atcggagtca cggacaattt
       61 cttcgcgctc ggcggggact cgatcaaagg aattcaaatg gcaagccggc ttcagcagca
      121 cgggtggaag ctggagatga aggacttgtt tcagcacccg acgatcgggg agctcagttc
      181 ttatgttcaa gccgctgacg ctaaaccgat cgatcaaggc cctgtcgaag gcgaagtcac
      241 actgacgccg atccagcgct ggttcttcga acggaaattt acgaacgagc atcactggaa
      301 tcagtcggtc atgcttcacg ccccttcagg gtttgacccg gagctcgtcg aacagacatt
      361 ggcggcattg acagagcatc atgatgcact tcgcatggtt tatcaaaaga ataacggccg
      421 cctcattcaa tataaccgcg ggccggatga ccgttcgttc gcctttcgag tggttgacct
      481 gcgatatgtc accgacattg aaacggaaat agccgctcaa gcaaaccgcc ttcaggcaag
      541 ccttgatctt gaaaacgggc cgcttgtaaa ggctgaacag tatcagactg cggaaggcga
      601 ccatttgctg atcgtcattc accatttggt gatcgacggc gtgtcatggc ggattctgct
      661 ggaagacttt gcatcaggct attcgcaggc cgcacagcag catgatgttg ttttccctga
      721 taaaaccaat tcgtttaaag actgggccga agcgcttgag gcttatgcgc aaaccgaacg
      781 cttccttaaa acggccgatt attggcgcag acttgaacaa gagcgtattt gtgagctgcc
      841 gaaagatcgt gctgccgcag aaagaaaagc ggaaaacacc tctgctgtta agtttgaatt
      901 aagcgaagcg gagactcgtc tgctgctgac gaaagtgcat gagccgtatg gaacggatat
      961 caacgatatc ctgctttccg ctctcagcct gacgatcagg gaatggacga acggctccaa
     1021 tatttgcatc aatatggaag gccacggcag ggaggaaatc attccaggga tgaacatttc
     1081 gagaacgacg gggtggttta ccgcacaata tccagttgtt ttaaaaagcc aagcagcggc
     1141 agggttgcct gagaccatta aaaacgtcaa agaaaccctc cggcgcattc ctgacaaagg
     1201 aatcggctac ggcatccttc gctacttaac agaccggaaa aaagccggtg caattttctc
     1261 gatcaagcct gacatcagct ttaactacct gggacagatc gacagggagg tgcagaccgg
     1321 cttctttggg ccttctcctt atgatatggg aagacaggtc tctgaaaggt ctgaagcact
     1381 ctatgcactg agcttcagcg gcatcatcag caaggaaaaa ttcatcttgt catgttcatt
     1441 caatacagag gaatatgaca ggcagaccat acaggagctc atggacagat tcaaagcttt
     1501 cctgacagca ttgatcgacc attgtacagc taaagaagaa cgcgaattta caccgagtga
     1561 tttttctgcc ggcgatcttg agatggaaga aatgggcgac ctgtttgacg ttcttgaaga
     1621 aaacttgaaa taaccaccga ggacttgccc gcttgtcaag cgggcgagcc tatgaaaggg
     1681 ggatacgatc ttgagccagt ttaaaaaaga acatgtccaa gacatatact atttgtcacc
     1741 gatgcaggaa gggatgctgt ttcatacgct gctgcatccg gggcaaggct tttatattga
     1801 acaaatcagc atgcaggtga aaggttcttt tcaaaaggat gtattggaaa aaagcatgaa
     1861 tgtcatcatc ggcaggtatg atatattccg aaccgttttc gttcatgaaa aaatgaaacg
     1921 tccggttcaa gtcgttttaa aggaaaggtc atttcaggca gaagaaattg atctatcagg
     1981 actttctgaa gcagaacaaa atgagagaat tgaagattat aaacgaaaag ataaagaaaa
     2041 aggatttaac ctctcaaaag acattccgat gagaacggcg gtttttaaga aggggcagga
     2101 tcgttacgaa tgggtgtgga gctatcatca tattctgctt gacggatggt gcttcggcat
     2161 tgtcgtacag gagctgttcg aagtatacaa cgcgctccgt gaaaacaggc catacagcct
     2221 cgggcctgtc agaccttaca aagaatatat taaatggctc gaaagccagg acaaacaaaa
     2281 atcgctggtc tactgggaac atcatttagc cggattcgaa gggcagacga cattcagcga
     2341 acagcggaaa aacccggagc aagccggcaa tcagccggaa gaactgctgt ttacacttcc
     2401 aaaagaagat acagaagcgt tcacacagct agcaaaagcg catcatacca cgttgagcac
     2461 ggcgcttcag gcggtgtggt cggtgctgct cagccgctat cagcgatccc gcgatctgat
     2521 cttcggtaca gttgtttcag gccgccccgc tgacattcaa ggtgtcgagc acatggtcgg
     2581 tttgtttatc aatgtcgtcc cgaaacgggc gacctttggc ccgcaaacga cctttacgga
     2641 gctggtcgct gatttgcaga agcaggcgct cgaagctgaa ccgcatcaat atgtgccgct
     2701 ctatgaaatt caaagtcata tagcagcgcc gaacttaatc gaccatatta tcgtttttga
     2761 aaattacccg ctgcaagaag ccaataaaca gcagaaagaa aaaaatctcg gcttcacaat
     2821 ggacgagatc agcgtttttg aaaaatcgaa ttatgatctg aatttgcttg cttcaccggg
     2881 tgaagaaatg atgctgaaac ttgcatacaa ccggaatata ttcgaaccat ctttcatctt
     2941 gcggttaaaa gaacagcttt tgacagccat tcgcgaggtc atcagagatc cggagcagcc
     3001 gcttgacgac atttgtgtcg tttccaaaaa ggaaaaagag cgacttctcc atgaatttaa
     3061 cggtcaagtc caacggaagc aaatcggcct gacgattccc caatggtttg agcaatacgc
     3121 tgaagcgctc ccggaaaagc ccgcggtatc agcggccggg cggacgctga catatcggga
     3181 attgaacgaa aaggcgaaca aggtcgcgca ccttttgcgc aaaaagaacg tcggccgcgg
     3241 cgagcccgtc gcccttttgt tccgccgttc gccggaaatg gtcatcgcga tactcgccgt
     3301 cttaaaagca gggggcgcct atctgccgat tgacccggaa tatcctgaag cacggattca
     3361 gtatatgctg gaagacagcg gggctgtttg catgctgaca caggaagagc ttgccggccg
     3421 ggcggcgtcg ctttcttttc ataagcatac gatcctgatc gacgatcctg ctgtgtctgc
     3481 agaaagcggg agaaacctcg aaatcgccgc cgagccggac gaccttgctt atatcatgta
     3541 tacgtctggc acaacgggaa aaccgaaagg caatctgacg acacatgcca atattacaag
     3601 ggttgtaaaa gagacaaact acatcagcct ttccgagaaa gacaccttgc tgtccctttc
     3661 aaactatgcg tttgacggct tcacatttga tctgtacggc gcgctgttaa acggagcaaa
     3721 gctggtggtg gccgatcagg cgacgattct ccatatcggc aagctgacag aagcgattca
     3781 gaaggaaaac atcacagtca tgtttgtgac aacggcgctg ttcaacttgc tggttgatgc
     3841 gggaacaggg tggatgaaag ggattcgcaa agtcctgttc ggcggagagc gctcatctgt
     3901 cagccatgtc aagaaagcat ttgctgccat gggaccggac aggatcatcc atgtatacgg
     3961 gccgacggaa acgaccgtct tcgcgacgtt ctatccggtc aaccgtatgg aagacagcgc
     4021 ggtttccatt ccgatcggca agccgataaa cgaaacgaat gcatacatcc tgacggaaaa
     4081 taaccggctt cagccgattg gagcggtggg tgaattgtgt ctgagcggta caggagtatc
     4141 gcgcggctat ttgaacaggc cggaactgac tgcggaaaaa ttcgcgccgc atccgtttaa
     4201 cagcggtgaa acgatgtaca ggacgggaga tctggcccgc tggctgccgg acggcaatat
     4261 cgacttcatc gggcggatcg atgatcaagt gaaaatccgc ggacaccgga ttgagctcgg
     4321 tgaaatcgaa gagcagctga tgcgctgcca aggcgtaaag gaagccgttg taaccgccag
     4381 gaaaagcggg aacggggatg cggcgctcac cgcttatgtc gtcccggtgc agggaactga
     4441 ggttgcaaac gaggaggttc gccgccaatt ggcgcggagg ctaccggctt acatggtgcc
     4501 ggctgcgtat atcatgcttg aagagctgcc gcttaccgct aacggaaaag tcaaccgacg
     4561 ccttctccct gaagccgatg gccggccgaa ttcaacagag cgccgtgcac cccgcaatgc
     4621 tacggaagaa aagcttgcag tgatttggtc tgaggttctc ggcagacagc agatcggaat
     4681 agacgagaac ttttttgaaa tcgggggaca ttcattgaaa gccatggccg tcgcctcccg
     4741 gatgctgaaa gatctcgcaa tcgatgttcc ggtgaatgtg ttgtttgaaa tgcccacaat
     4801 cgagggcctc gcggcttata tcgaccaagg cggccatgtg gatgaagtga aaaaaaccgt
     4861 cttcaatcag gcaagcaccc gccatttgtt cgctttcccg cctgtcctcg gatacggcat
     4921 catgtacggc aagctggccg aacaaatgcc ggaatacagg attcacgcgt tcgactttat
     4981 agaaagcgat gaccgcgctg tgcgctatgc agaagccatc tccgaccttc agcctgaagg
     5041 gccgctgaca ttgatcggct attcagccgg ctgcggactt gcctttgaag tggcgcaagc
     5101 gctcgaaaag aacggacgga aggtcgaaaa gctgctgatg atcgactcat atatgaagaa
     5161 cgatgtcagc gatttagaag ggcggtcaat tgaagccgat acggccgcct tgatggaagc
     5221 caacaaggac aatgaatata tgaaaatcaa gacggttgcc gatggcatcg ccaaaaagat
     5281 gacagcctat tattcttact ttgtcaatct tgtccatcaa ggaacggtca gctcggagat
     5341 tcatttgatc aaatcagagc acgcaaaacc gctcccggca tggctttcgt tgtggaaaga
     5401 aggaacggag tcttcatatg atgaatatca aggcgctgga agacatgatg aaatgcttgc
     5461 ggacggcttt gttaaaagca acgcagatct catcagacag attttgggcg aacgtgccgc
     5521 tgtaatcgga ggtgcatgat gcatgaacga gatcattaag cagtttggag cgccggcaag
     5581 cggtatgcag ttgatctgtt tcccgtttgc cgggggatat tcggcatcat tcagaccgct
     5641 tcacgaacat ttaaaaacag attttgatat gctggcgatc gaaccgcctg gacacggcac
     5701 aaatcgaatg gcgcttgtcg acaatttgga aaagctcgcc gatttgtata tagcggcgct
     5761 taagccgcgg ctttcctctc aattcgtgct gttcggccac agtatgggcg gcatggttgt
     5821 ttacaggctg gcgcaaaagc ttgaacaaga agggatcttt gcggcagccg ctgtgatatc
     5881 agcgatacag ccgccccata ttcagcggca aaaggtgtct caccaaaagg atagcgcatt
     5941 tctcgaccat ctcattcagc ttggcggaat acccaaagaa ctggcagagc acagggaaat
     6001 gatgaacttt ttcctgcctt cgttcagagc ggactacaga gcgcttgaga cgttctgcca
     6061 taccgatcat acgccgctta gatcgcctgt gcatattctg aacggagacc gcgatgagaa
     6121 atgcatgagg gatgcgcttg gctggaaaaa gtgggcgaat acgatcgatt tccactattt
     6181 caaaggcgga catatgtatc ttttatcaga aacggaacaa gtagccgcca agttgaaaac
     6241 gattgccgcg gccagccgca gtacggctgt tccgacaatg taaagaaagc ggaaaatcgg
     6301 tgtgctgcag ctgccgattt tccgtttttt cagctttttt tcagccgatt ttcccgccga
     6361 accatcgtcg ccccaataat tccggcaatg atcatccccg ttccggcgaa gtgaaaccat
     6421 tcgagtgatt ctcccagcca tataatcccc gccaaaatcg tcaccagtgt cgccaagtga
     6481 ttaaacatgc tgattttcgc agcttctatt tttgacagtg cataatttga taaaaatgat
     6541 gtcgcaaacg atgacaacac gcctaaatac aataccgaaa gaacaaacac cggatcagtg
     6601 aagggggcaa aaaatccgct cagcgtgccg tctgacatat ggctgattcc ggcgatgccg
     6661 ttgaaaaaaa gaaatcccgc tcccgttgtg acatatgtta attcaagcga gctgaaggtt
     6721 cgcgtcatct ttctggcgag cacgctgtag cccgccgatg aaagcgccga aagcaaaatc
     6781 agcgccgccc ctcttaaatc ggaacttccg gtgcctgcac ttttcatcat aaagatgcag
     6841 gccacccccg ccgctgacaa gacggtaaaa aagaattgcc gtttcgtaaa ccgctcattt
     6901 aaaaaataag cggcgaatat catggtgaaa atcgggatcg ccgcttgaat gattccggct
     6961 tcagacgaag acgtgtagac gagcccgaaa acttgaaaag caaaaaacat gacagggtaa
     7021 aataatgcta aaggcagcac tttcagtgcg tcttttatgc tgatggcgat cttcacccat
     7081 ccgagcagaa ggggaataag cgcagccaaa aaagcgaccg taaagcgatg ggccagaatg
     7141 tcgaccggac tcgctgcagt gagagccaat ttgacaaaga aaaaggaaaa tccaatgata
     7201 aaagcataga gcaaagctgc cgcataagca gatttgttca aagtcgatca tctccgttaa
     7261 agtatgcatg caatacagat attttaccgg cttctgtcat cttatacgga agcgaaatct
     7321 gatacaatac aaaaaaacgg aatctgtacc gttacagatt ggcgaaggag acgaacatgc
     7381 acaaatatgt cgcactgatg aacgaattgg aggatatgat cgaagacaaa tcctttcagg
     7441 aaggggacag gctgccttcc atccgcgcgc tggccatacg tttcaaggta agcaaaagca
     7501 cggtcatcag ggcgttgaac gagctggaaa gacggcacct catctattca gtgccgaaaa
     7561 gcggctatta cgtcgtgaaa aaaacgaatc agcggcccaa ctccggaaag gctgtaatcg
     7621 atttcgcagc atccgctcct gatccggatg tttttccata catcgatttt cagcattgca
     7681 tcaataaagc catcgataca tacaaaaacg atctgtttat ttatgggacg ccgacaggtc
     7741 tcccgtcgtt aatccaagcc gttcagaaag agctcgcaaa cagccaggtg tttgcaaaag
     7801 aggaacacat atttattaca tcaggcgtcc agcaggccct cgccttgctc gcttcaatgc
     7861 cttttccaaa ccggaagcgg aaagttctga tcgaacagcc gagctatcat ttattgatta
     7921 aataccttga agttcacggc atccccacgg tcggcatcga tatggacgag ctggagcgca
     7981 tctttcaaac cgaagatatc aaattttttt atacgatgcc gagattccac aatccgctcg
     8041 ggacatccta cacggaacgg gaaaaaacgg ccatcgtcaa gctggcggag aaatatgacg
     8101 tctatattgc cgaggatgat tttttaggag atttggagaa tgataaaaag gcggatccgt
     8161 tacattacta tgacgtttct tcccacgtta tttatttgaa aagtttctca aagattattt
     8221 ttccgggtct gcgggtcgga gccgccgtgc tgcccgattc tctgacaatt gtgttcaacc
     8281 ggtacaaaca gctgctcgac attgacagtt ccatgctgtc tcaggccgct ttggagatct
     8341 atttgaagag cgggatgttt gaaaagcata agcaaaagat ccgttcttcc tatcaaaaaa
     8401 gatcatgcct tctgcatgat ctgctaaaag aatgttccgc gtctctaggg gatgtgtttg
     8461 aatttcatcc tcccgcacag ccggctatcc acacccatat tgaattggac cggacgatcc
     8521 cggcatcccg tctgattaaa agcctacaaa aacgggacgt cctgctcgaa ccggtcaacg
     8581 ctcattatat gccggctttt ccaaaaagaa atctattgaa aatcaatacg tccaatgtga
     8641 aggaagagga catccgcagc ggcatcgagc ggttgcggca agcggtggaa accgcttatt
     8701 tttagggcgg gactttttaa agcattgaca gttcagcgca gcttttcatc acaatccggc
     8761 cgggaaattc aggtgcggcg gaacacaccg ccattttata gccggggtca atttcatagg
     8821 cttgtatata gcaaggcgga tagccggggg gagtttccac cgaagctcgc ccctgttcgt
     8881 tcagtttgac ggagaaggaa tcaagcggca gagacaggcc ttttcccgcc tgtttaataa
     8941 agctttcttt catcgtccac aaatgataga aatacgacag gcgttctgat tcgtcctttt
     9001 ccatgagatc atcgtgctcg gaaggtgaaa aaaaccgttt ggcaatgtcg aaattgatcg
     9061 gcttgatctt ttcgacatcc actccgatcg gctgcgcgcc ggctccgcac acgatccatt
     9121 ttccggagtg ggaaatgttg aaatgaaagt cgttcagacc ttcagcagcc ggtttgccgt
     9181 accttccttc tgtaaaacgg atctgctcat tcggcaaatg aaacgtttcg ctgatgatgt
     9241 gcctcgccag cacttctccg atcagcgtcc ggctggcatc ttcgggatat ctgtatctgc
     9301 ccactttttt tcgcttttct tcagacacca tggccatcat tcggttaaat tgaccggctt
     9361 ccggcagctg atccatataa acggcgtaaa tcttcatcaa acgcaacctc ttcacatgat
     9421 atttttctgc tttcatttta gcaaacagac agcaggaaag ataggcatga tacttgtgca
     9481 gaatggagta atgaacatga tagacggaac attgataaaa gatacatgct tcgggaggga
     9541 gcttttgatc tatcttcctc cttcatacgg gagcggtgaa aaccgctatc ccgttctata
     9601 cgtccatgac ctgggagatt tattcgatcc ggcatacagc aacagtctgc gctcaatcga
     9661 aaagctgttt tcgagtcagg aagtgccgga attgctgctg gtcggagtgg ctccaaaaga
     9721 tagggaaagc gaatacacgc cttttcccaa gcggcatttg ctgcccaata aacgggagta
     9781 cggcgggaag ggcaacgaat atgccgcttt tttggccaat cggctcaagc ctcatatcga
     9841 ccggcactac cgaacaaatc cgagccgtga acaaacagga atcatcggaa agtcgttcgg
     9901 agggttgatc tcggtttaca cagcttttct agcatcggag acctttggaa aaatcggatc
     9961 tttgtcaggt tctttctggt ttgaaggaat aaccgagttt atgaagaata accgctttga
    10021 gaataagcat ctgcgcattt atatggatgt cggaagcacg gaagggacag acagggataa
    10081 tctgcagaaa gagatgatac cgaggacaaa ggaagccttc agcctgttaa cagaaagcgc
    10141 cgcctccgaa aaagaactga aatttgtcat tgatgaaggt ggctcacatc ggcttgagcg
    10201 gtttgcgaag cgttttccgg aagccgttaa atggctgttt ggctcctgtc acaacagcgc
    10261 acggaatggc aggagtttct gattggcatg aagtatcgtt gtaaacgaga ggcgcggaag
    10321 caatggacat tctgaatcgt ttggctgaaa aacatcgatt atattgaaaa gcactggatc
    10381 agccgctgaa acacgaagac atcgccaaaa tcgcatattg ttcgaaattt cattatcagc
    10441 ggatgatcta catgctgacg ggtgtcacct ttgccgatta cattcggaaa agaaggctga
    10501 cagccgccgc gcaggagctg actgcaagtg gttgatgctg cttttaaata cggctacagc
    10561 acaccggaat cattatcggg aggccttcag ccgccttcac ggcatcagcc cttcacaggc
    10621 ccgagaaaaa ggcggacgct cagggcattt ccacgtctat cctttcatat tcaaataaag
    10681 ggagtggagg atatggatta caagattgtt gaaaaagaac cgtttcaggt gatcggcaaa
    10741 gcgttggagg ttacggtcaa ggatggtcaa aacaaaaagg atattccggc tttttggaac
    10801 gaattaaatc acaacggctt taccgattct ttaaaaccgc acatcggccc gcttggcttc
    10861 cttggcgtct gcatggattt taacgatcaa cccgatacgt tcaatttttg aaaaaaatac
    10921 cgcttacacg cctgccggct gtgtcgaaaa aacgattccc gcnnnnnnnn nnnnnnnnnn
    10981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnaggcc
    11041 atcggccccg tcaatccggc tggtcaagcc acatgggaaa ggatcttctc agaatgtttt
    11101 ccggcgactg gctatgaact ggcgaacgag ccgcaatttg aagcctatcc tgaggacggg
    11161 gatattatgg cgcaagatca tatcaccgaa atttggatac cggtggtaag cagaaataat
    11221 cctgaacgag aaaaacggat gaaacgctca tccgtttttt ttcagcgaca tatgtacagg
    11281 cttggcagct ctgatgcgcc ttcctgccat tgctgctttt aaaagctgtt tggactgcgg
    11341 caaagaaaac cgcaaaatca ggccggttaa aatggcggtt aaaacagtac cgatgccgat
    11401 cggcccgccg agcagccagc cgatcaataa aatcgtcagc tccattccgt ttcggaccca
    11461 ctgaacgttc cagcccgttt tctcggaaat caaaagcatc agggagtcac gcggacccgc
    11521 accgagatcg gccgatacat aaatgccgac tccgtaaccg ataaaaataa cgccgatcac
    11581 gaatacgaca gtgcttgaaa tatacgtttc cgggtctgga agaatataag taaagaaatc
    11641 tataaaaata ccgattaaca gcatattgag cacggcgccg attttcggcc atgcttttgt
    11701 aaataaggac gttaaaccta cgatgaccgc cccgacaata atcgcccatt ggccgaccgt
    11761 aaggcccaaa agcatataca gcccgtagtg aaacgcatcc caaggaccga tgccgagcac
    11821 tttcccttca atcgtaagag aaaccccgaa agacaaaaca atcaatccga caaaataaaa
    11881 aagccagcgc aaaacaagtt cccgcttcaa tggattcccc tcttttcaaa aaaacaatca
    11941 attgtcattg tatcatattc ttcagtgggg tgatatccaa aaaatgtttt attttgtgta
    12001 atacttgtac caaactttat taaaataaca attgactaaa agatatttcc attttataaa
    12061 attaatgtat aatatttact agtaggtgat ctttataggg atagttgctt aaaaggtata
    12121 tagactttaa tggatttggg atcattctaa aaaaggagag taaacatgaa gaaactttat
    12181 attagtgctg tcctgggttt attgtttgtt tttgttggtg gaacaaaaat acatgctcaa
    12241 gaaccacaga acaataacgg ggttttggat gagaataaat tcattgatga aacagtgtat
    12301 tcatatacgc agccaattag catacaggat ggtgaagtga caacacaagc gaaaaaatat
    12361 atcaaaaccg tgtcagttaa taggagctat aaaagtcttt taaacattgt agttgccaga
    12421 cattactctg atactacttt cacttacgga agcggtaagt tatataagag tcccagagct
    12481 ttaagtaatg attggtggac acttcctccg aattttaaat caggaagctc taaaagctgg
    12541 gactggtaca atacagggaa aggtgcaaca ggacgttcta atttacaagt aagatacact
    12601 tggggagttc caacaccatg ggggccagtt ggatctaatt atagctcaag aataaaggtt
    12661 tcatttaaat caaatggcag ttggtataca aattaaagct atatatgaaa ggtgacatac
    12721 cgatgggtac aatagggata aactttaaaa acattcaaca tcaatatcgt acgaaggatg
    12781 tgctaagggg ggtgagtttc catgccgatc cctcctccat cacgttcttg gcaggcgaga
    12841 atggagccgg aaagacaact ttgataaagg ttgctctcgg cttaatcagt ccgaaggcag
    12901 gaaatgcgct gttcgacggg caaagcgtcg gggaaatccg ggagaagatc agctgcgtgt
    12961 ttgatgagcc tcctgtttat cctaatgaaa gtggtcttga caatctaaag tttttatcag
    13021 gtatacacag ccttgatcga aagtggagtc aggaggtttg tgccatgctc aaattggatg
    13081 agggactttt aaaacaaaaa gcaaaagcgc tatcactggg tcaaagacac cgtttagctg
    13141 tagcggccgc gttattgcgc aaacctaaat atttgtttct tgatgagccg tcaatcggcc
    13201 tcgacccacc gtcatggcag ctggtccaaa tcgctttaaa acagatgact gccaggggat
    13261 gtgcaatttt gattacgggg caaaattatg acgcgattga aaatctcgct gacaatatag
    13321 cgattttgca aagtggaaaa attatcttct ccggtcctat tgtaaaactt gttcaagcat
    13381 ttcccgtata tgttcgaatt gtaactgatg accatcggga aatagctgtg cagtttccag
    13441 aagctgaacc tgattcttcc ggaatatacc gcatcgtttg cgaatcaggt gaacaggccc
    13501 gcgccgtgat taatcaggtg aggagaagca ccctgaattt tcaagagcta tcgactgaaa
    13561 aagcgtcaat ggggaaaatg gtgacagata tttacaagga tggatttcag tcggaaaaga
    13621 gagggttaac gtatgaatcc gttcaaaatt gaaacgaatc aattgaagaa tagcatgctt
    13681 gtgagggttt gtatcgcgtt attattttgt tgctttatct gggggcttct cactttatat
    13741 caaagcgctg aaggcgagga acgcagacag gaaaagattc accaatccgt cattgatgaa
    13801 gtgaaaaaga atggggcgga ggaagagctt gaaaacggcg gattggagat tgaaaaaaat
    13861 gatgatatag cgcgtagtat gtacatagga cttcatccaa gtgttactcc taatctgttt
    13921 ttattaatcc tcgcgaacat tgggccaatt gtttttatta taatcggatc tcaccttgtc
    13981 ggaagcgaat accatcaggg gactgtgaaa atgaaagccg ctcacatcgg atggagaaaa
    14041 gcggtttctg gaaaactatg cgcactgtta agtctggtta ttgttatggt tattgcagct
    14101 ttattgcttg gactggcagg cggttggctg gcttggacgt tcgccacggc acattcagac
    14161 ttagccgctt ctcttgaagt gaatgcagct gtctcctatc cgatattaat tttgttttta
    14221 atgatcggat tgacatttta cagtgttcta ggaatgactg tcacgctgtt gacgaaaagc
    14281 cggctggcgg gtgtgctgat cagcttggcg atcccgtatg ctgagcaaat gatgagtctg
    14341 ccttttttgc cattgactgc ttatcaatcc ctcatggttc accattttat ttatgtcgac
    14401 ggaagcatca tcggccagcc ctatttgaca gagccgatgg gcgaaccggg cgcttgggct
    14461 gttcttgtat gctggctctt tgttgtcatt gcggttcagc agtttgcagc gaaaaaacag
    14521 cagattttat gaaaaaaggg gggaatggcg ttgatttttt tagttaggct gatctgtctt
    14581 gcctttttag cctgtctggc gctgttgttt tatgcacctt ttctggcgat gcccgtttgg
    14641 atcgctttga tcattgcctt aatcgtctgt ctgtatcttg cctttataga ggaaatgaag
    14701 gaatggagaa gacgaaagca ctaatccttt cttcagcgtt ttttcttgta taaaagaacg
    14761 tttgctaaaa cgaaatagat gacggccgtc ccggacacaa acaaaaaaat tctttccact
    14821 ctaatgccgt catgtatgcg aagcggagga gttcgagatg ttcatccaag taataagcct
    14881 gggtatatgc gccgactgtc atgccgataa aggcgaatag accgaccaca ttgagcacca
    14941 ttctcatact gaatgtcttt ttctcttttt ctctttttcg tggttcattt taaagaaatc
    15001 ctttccaata tgaatttatc attctattgt acgaatacaa cgcttggatg attcaaaaac
    15061 ttcttaatct attgttaaga agttttttta ttttggagaa aatgtaaaag ataaaacaat
    15121 ttcatgaact ttttgagcga aggcctaaaa atataggaat attataccga tatggcaagt
    15181 gaaatctttt tctgaaatat aaaagacaag gcaggagaga aaatcatgca gcaacgcaat
    15241 acaccggatg tacagagatg gtttccgagc gaggacggaa atgaagcaaa acgaaacgag
    15301 ttcctatcat tgatcgagca gctgatcgag ggagtggaca acctgaaaaa tccggatcag
    15361 gtcaaccttg gcggcgagaa gaaccgagag ggcttctttt atgaaaagct ggttgcagag
    15421 agtcggattc cgcatgaagg tgcgccgatg aaagaggtta acgaagagct gttgaagctg
    15481 ttgcacggcc atccgtatca caccaaatac tttttcacga acattctgcc gatggccagc
    15541 atcccgggga tattaggcat gcttacggcg tttatggtca atggcaacaa cctgtgggat
    15601 gtgtacggtc cagccggagc ggaggcggaa gtgaaggtta cagcgatgat gtcaaagctt
    15661 gctgggtatg atgccgaaac aagcggagga tatacaacgt ggggaggaca aggggcggta
    15721 tacagcggcc tcagaatcgc gattgccaaa atggctccgt catccctaaa agaaggggtt
    15781 cccggcaatt tctatgcgtt ttgttctgaa gcggctcatt acagcttgta taagtcgatg
    15841 gaagccgcag gactcggcag cgatcattta attaaagtca aaacaaatct cgaccattcc
    15901 atggatacgg aagatttgcg agagaagctt agacaagtat gcgaagccgg gggcattccc
    15961 gtctatatcg tagccacgac gggaacgaca gatgcgatcg gcatcgatga tgtgagcgct
    16021 gtccgccgtg cggctgaaga aaccgcgaag agcttcgggc tgccggttcc gcatatccac
    16081 gccgattccg ccctgggagg attttttgcc ttttttaatg agtacgatct gaatgagaac
    16141 gctttatcct tcagtcccgg tgtcctcagc atgatcaaac cgattcagga aaaaatgagg
    16201 catctgcatg ctgccgattc gctttgcttt gattttcaga agctcgggca gacgccttat
    16261 gtgacgagcc tgtttcttgt gaaggatcgc aatgacttaa aacggatcga tctggatccc
    16321 gatgagacgc cgtatgtcgg ccaccgcggc tatggggact accatacggg ctacacgctg
    16381 gaatgttcgc gcatggccag ttcgatcagt atgtacagcg cattgatggc atttggctat
    16441 gaaggctatc aaaagctgct tgcccagttc cttgaagtca acctgcattt tagggaacag
    16501 ctgtctcggc agattccgga ggccgatatt gtgaacccgg acaactgcgg catgtctacg
    16561 ctgtttcgca tttatcctga aggggcgcct agatttgaag acgaaatttc gggagcatgc
    16621 accattgaag agctggaaag aaacaatgcg cttactgaaa aattatttga aaagctcgga
    16681 acaaaaaggg acaagatgtt ttttggcgat acgaaaaaac acttgcttgt gaagtcctgt
    16741 gaaggggttg aattaccgct ttgcgtcagc aaatttttcg tcatttctcc gtataccatg
    16801 cctgaacatg tcccgggaat tatcgattat ttaaaagaaa ctattgagga agtcttccgg
    16861 gagcatgggt ctctcatgac aaattaaagg ggatatagac gatgaaaacg tttaagaaaa
    16921 agctaacaga acacatttca gtcaaaatta tgattggcgt cgccttagtg cttttaatca
    16981 cgatcgcatc attttcagcc gtgtttactt ttatcagcaa agacttgtca gagcagctga
    17041 aacagcagtt ccaaaaccgc ctttataccg atattcatct tgctgaaaat caaatcaaac
    17101 gtctggacgg gaatccgctt gagatcgatt ccgcagacgg tccgctttac aagcagacaa
    17161 aaatggctgt ggacagcctg aaaaagaaaa acaaacttga gaatatttat atcctttcca
    17221 atgaaggcgg gaaggagcgg attctcgtgc tgtcggatac gcccgatgat ttcggcacgg
    17281 attacagctt ttctcctgaa atgaaagaag ccttgacgac aaacaaagag acggtaagcg
    17341 acgtgtatga ggacgaatac ggcatccacc agtcgatttt tctgccgctt gagaacggct
    17401 caggagaaaa ggtgggaatt ttggggatcg accttgatgc ttccgtgatt ccggagacag
    17461 cggcaaaagc gaaatggtat acaattgcga tctcagcatt tgtcttgctg ctcggaatgg
    17521 tcatggccta ttttctcggt tcttacatcg cgaagccgat caggcagctg atgaaggctt
    17581 cagaaaaaat tgccgacggc gatctatcgg ccgacatttc tgtcaagagc cgggacgaag
    17641 caggaaagct tgccgaatcg ttcaagcgga tgagcgaaaa tttacaacaa ttgattggac
    17701 atatttcagc ttcctctgaa gaggtatcca agacgagcct gcagctgaaa aatgtatcgg
    17761 ctgaatcgag cgaaagcgca gctcaagtgg ctgaatcgat gaacagcatg agcgagggaa
    17821 tcaacgaggt tgtctcttca gtttcggatt gtcatacatc ggctgccgaa atcgatcagc
    17881 agcttacaca tgtcacagaa aaagtgaacg agatgaagaa cgttgccgag ggcgtcagca
    17941 aggattccaa gacggggcag gagcttgtcg aagaaacatt gcggcagacc cagacgatta
    18001 aaaacgtgat ggaagagtcc aaacaagcgg catcagagat gcaaaaccat acagaagaaa
    18061 ttgaaaaagt catcggaatg atttcctcta ttgctgaaca gacgaatttg ctggcgctca
    18121 atgcttccat tgaagccgcc cgggtcggtg aggaaggcca gggctttgcg gttgttgccg
    18181 gagaagtcag aaagctttct gaacgttcgg cagatgccgc tttatccgtt tcccagcttg
    18241 tggcgggcac gcaggagagc agccggcttg tcatggaacg cattcaggaa ggaaacgaag
    18301 cggttgacaa agggcagatt ttaatcaatg gcacatacga gaatttttca ggaattttta
    18361 aaggaatttc tcaattcgcc gaacgcacag atcaattgct tcagtccttg ttaaaagtcg
    18421 aaaaatcgta tcaaaccatt tcgtctgcga tggagcagat ttccgccgtt accgaagagc
    18481 aggcggcagg ctctgaagaa gtcgctgcgg cagcggagca gcaaagcgcc ggcatgcagg
    18541 aaatcgcatc ggccattcag cagctctccg ctttgtcgga agaattgaat caggcggcat
    18601 ccaagtttaa actggccgct gaataaaaag aacagcctga tctctcttga tcaggctgtt
    18661 ttgtttatac aggattcaaa atccggttta aaaacttttt tgttcgttct tccttagggg
    18721 ctgagaaaat ttgttcaggc gggccctgtt cgacgatgac gccgccgtcg ataaagacga
    18781 cttcgtctgc gacatcctgc gcgaatttga tttcgtgggt gacgacaacc atcgtccagc
    18841 cctcatttgc aaggtctttc atgactttca gcacttcgcc gaccagctcg gggtccagag
    18901 ccgatgtggg ctcgtcaaaa agcatcagct caggcttgat ggccagggcg cgggcgatcc
    18961 cgacgcgctg ctgctgtccc ccggaaagct ggaatggata gagatccatt ttgtcttcaa
    19021 ggccgacctt ttgcagaagc tgaacggctt cctttttgac ctcttcttta ttgcgctttt
    19081 gcacttttac aggcccttcc atcacatttt cgagcacggt gcggtgcggg aacaggtgat
    19141 aggcctggaa taccattccc gactttctcc gcaggcggag gaggtcagca ggtttatttt
    19201 tcttggaaaa atcgatggtg aaatcgtcaa aagaaagaat gccgcggttt ggaatttcca
    19261 aagcgttcag gcagcgaagc agcgtcgttt tgccggaacc ggaaggccct aaaatggcga
    19321 tcacttttcc tttttcgatg ttcagatcga ttttttttaa gatttcattt tcgccgaagg
    19381 atttattcag ccctttgatc gcaagcatgg tctatttccc tccttacttg gccacatacc
    19441 ggtccaaacg ccgttcaatc tgctgctgaa caagcgcgag aacaaagcag atgatccaat
    19501 agatgaatgc ggcttccata taaatgatta aaatttggtc aagattgccg gccccgattt
    19561 cctgggcctt ccggaataat tcagcaacaa gaatctgtga cgcaagcgat gtatctttaa
    19621 ccaagctgat gaatgtattg gataatggcg gaattgacac gcgcacagcc tgcggcagga
    19681 tgaccctggt aagcgccgtt ttttgagtca ttccaatcga ataagccgcc tcccactgtc
    19741 ctttcggaac ggaaaggatg gaagccctga tgatttccga cgcataagcg ccgacattta
    19801 atgaaaaggc aatgattgcg ctcggaaacg ggtcgatcgt gacttgaaac gctggaaaca
    19861 agtaaaaaat aatgaacagc tgaacgagca gcggcgttcc gcggatcgct gagacataaa
    19921 tgccgaaaac cgctcttaaa atgcgggatt tggacattct cgccagcgcc gtgatcaatg
    19981 cgatgatcat accgaatata aaagagagaa tggcaagggg aatcgagtaa tagattcccc
    20041 ttaaaaagat cggccaaaat gactcacgca caagatccca cgggatcgcc tggctgatgg
    20101 ccgccgcttg tatattactt agaaacatct tcgccaaacc atttcttcgc tattttcgcg
    20161 agtgtgccat cctctttcat gtccttcagc gcggagttga ccttgtcaac cagttcgccg
    20221 cttcctttgc ggaaagcaaa atgcgtagtt tgcggctcgc ctgtttcaaa agcgattttc
    20281 aggtttttgt ttcctgacgt cttcaaatag ttcagcaccg ccagtttatc gttataggtg
    20341 aggtcgacac ggccctgctg aatcagctga aacgcttgag ccattccttc tacgccttcg
    20401 atttcagcgc cggcgttttt cgcaaggtca ttatagttgc ttgtcaaaga ctgcgcggct
    20461 tttttccctt tgacatctcc ttcagacttt acatcgttgt tgtccgcttt tgtgacaacg
    20521 acggcttggg aagttgtata tgaatcagaa aaatcgtact gatcttcacg gtcttttttc
    20581 ccgacttggt tggcaacgac gtcaaaacgc tttgagttga gtccggcaaa catgctgtcc
    20641 cactgcgttt ctttaaattc agctttcagg ttgaggcgct tggcgacttc ctgcatcact
    20701 tcgacatcat aacctgttaa tttatctgtt tttttatcgt ggaatgtaaa aggttcgtac
    20761 gttccttcag taccgactgt caatacgcct ttatctttaa ttgaagacca gaggctgtcg
    20821 ccggctgcgt ttttatcctt ggaattgtcc cctgacgcgc cgcatgcggc catcacggtg
    20881 atcaacagcg tcaataatac agcgaatatt gctttcttca ttttattccc cactttactg
    20941 attggattta gttgatatga ttttacttaa ggctcttaca aaagtaaagc ataaaccttt
    21001 tttagtatga gtcaagaaat acgtttttag tgatgaaagg gagagaagat cattctgatt
    21061 cctgatcgaa gcggatcttc cattttttaa gcctgtattg caggctttgc ctgctgatcc
    21121 ccagcacccg agccgcttgt gacacattgt aattgcattt tttaacggtt ttttgaatat
    21181 aatacttttc ggcattctcg atttgttcct ttaaaggagc ggccgaggcg gaaggaagcg
    21241 gggcgaacag atcatagccc tgctgcggca gctgctcttt tgccgctggt ttcgtcctgt
    21301 attgcaatgg aaggtgcgtc agctcgattt tgtcttcgta ggacatcaaa ttcatggcgc
    21361 cttcaattaa atgttcaagc tccctgacgt ttcccggcca atcgtatgaa agcaggaacc
    21421 gccgcacctc ttcttcaaaa cccttgacct ccatttggaa caatgcgttg tatttgtcga
    21481 taaaatgctg cgtgagcggc ataatatctt ccttccggtc ttttaatgga ggaataaaca
    21541 aggtgacgac gctcagcctg taatacaaat cttttcgcag cctctggccg ctgacagcgt
    21601 cgactggatc ttcgttcatc gtcgcgatga tcctgacgtc gatcggagta tcctttgaag
    21661 cgccgatccg cctgatcgtt ttttcttgaa tcgcgcgcaa aagctttgcc tgcaatctga
    21721 agtccaaaga attgatttcg tcaaggagca gtgttccgcc gtcagcttgt tcgaaaagac
    21781 ccggacgatc cacggctccc gtgaatgcgc ctttgaccgt gccgaataat aggccttcga
    21841 caaggctttc cgggagggct gcacagtttt gcgagatgaa tgggcccgtt gagcgctggc
    21901 ttccgttatg tatactttgg gcgaacagtt cttttccggt tccggtgtcg ccaacgatca
    21961 gaatggagga agaggtccgg gtcgcccgct ttgcatgttc aatgacttcc ttgaacgccg
    22021 gactgacgcc gatcaggctg tcaaacgtat actttgtgct ttctgttttg ttcatatttt
    22081 ctctgatcag gcgttcaagc tttgtgacat ctttggcaat ctcgaccgct cctttcgtat
    22141 tcccgttttc cataatgggg aatgtatgat tgacggtcgt aatttcctgt cctttgttat
    22201 taaagtaagt ctgtttgacg tttttgttcg ttttcccgtg atgcagcgcc tgcaggaggg
    22261 tgctgtcatg ctggctggca aacgtaaaca cgtccagcac gtttttgccg agcacatcgc
    22321 cgacatccat cccttcaatc tggctcatct ttttgttata gacaacagat gtgccgtttt
    22381 catcgacgac atgcaagccg atatcgattt catctataat tccttgaaaa ataagtttca
    22441 gaaaatcata atccttcagc aattgatatc cccctttgtt cgtatctgtc tccattttaa
    22501 gtgaagactt gataagggtg caaaaaaata tgcatttatt tttgcacctt tgcataaaaa
    22561 ccgcaaaatt ttttgcgagt tacacatgca atgttctgaa aatttgcggt attaagagtt
    22621 ggcacgatac ttgcatataa gatagtgtga aacaaaatac gacatctggc atgtatgtcc
    22681 aaaaataaga aggaggaatc agaatgacgg ttctatcaaa gtccgagaaa attatgaagc
    22741 aaaccgcaca ttttggcgcg aataactatc atcctctgcc gatcgtgatt tctgaagcgg
    22801 aaggcgcgtg ggtgaaagat ccggaaggca accgatacat ggatatgctg agcgcttatt
    22861 ccgcagtgaa tcaagggcac aggcacccga aaatcatcca ggcgttaaaa gatcaggcag
    22921 acaaaatcac cctgacttcg agagcttttc acaatgacca gcttggtcct ttttatgaaa
    22981 aggtcgcttc attaacgggg aaggacatgg ttctgccgat gaacaccggc gcggaagcgg
    23041 ttgagtccgc ggttaaagca gcgcggcgct gggcttatga tgtaaaaggc gttccggaca
    23101 atcaggcgga aattatcgca tgtgaaggca attttcacgg ccggacgatg ctggctgtgt
    23161 cgctatcttc agaagaagag tataaacgcg gtttcggacc gatgcttccc ggcatcaagc
    23221 tgattccata cggggatctg gaagcgctga aacaggcgat cacaccgaat acagccgctt
    23281 ttttaattga gccgattcaa ggtgaagcgg gaattgtcat tccgccggaa ggctttttga
    23341 agcaggctgc tgaagtctgc aaagagcgca atgtcttgtt tatcgccgat gaaatacagt
    23401 cagggcttgc acgtacaggg aaaatgttcg cctctgattg ggaggacgtc acaccggata
    23461 tgtacatttt aggtaaagcg ctcggaggcg gcgtgttccc gatatcgtgc attgcagcaa
    23521 accgggatgt gcttggcgtg tttaatccgg gctcacacgg atcgaccttt ggagggaacc
    23581 cgcttgcatg cgccgtatcg atcgcagctc ttgaagtgct ggaagacgag cggctcgctg
    23641 aacggtcgct ggagcttggg gaatacttta aagaaaagct ctcgcaaatt gataatccta
    23701 aaatcaaaga agtgcgcggc agggggctgt tcatcggggt agagctgacc gaggcggcgc
    23761 gtccgtattg cgagcgcctg aaagaagaag ggatgctctg caaagaaacg catgagacgg
    23821 taattcgctt tgcacctcct cttgtcattt ctcatgagga tctggattgg gcgattgaaa
    23881 agattacccg tgttttgtcg aagtaaagcg aacggctgaa caataagggg attgttcagc
    23941 ccgttttttc gctgtctgtg cgaagtttgt caaaaattga aatatcaaga aaatgttcag
    24001 aagatttaaa aaatagtcta tatgtcatag ggggagctga cattagggag aattggatcg
    24061 gaaggggtga aggcggtttg aatcatgaaa accgtgaaca atatacactg aaacgaacga
    24121 tgaaatcccg ccatttgttt atgatctcgc ttggcggcgt catcggaacc ggcttttttc
    24181 tcggaacagg ttatacgatt aatgaagccg gaccgatcgg cgcgattctt tcctatttag
    24241 cgggcggaat gatcatgtat tttacgatgc tctgccttgg ggagctcgct gtggcaatgc
    24301 cggtttcagg ctcttttcag acgtacgcga caaaatttat cgggcctgct acagggtttg
    24361 ccgtcggctg gatctattgg ctcggctggt cggttactgt tgctttggaa tttttgtcag
    24421 cggggcagct gatgaaaaga tggtttcccg atgtcggcgt ctggatatgg tgcttgattt
    24481 tcgggctgct gcttttttca ctcaatgctt tatcggcaaa ggctttcggg gaatcggaat
    24541 tttggctgtc cggcatcaaa attatcgtca ttcttctgtt tattattctc ggcggaggcg
    24601 cgatgttcgg actcatcgac ttgaaagacg gacaggctgc accgttcttt tccaatctga
    24661 ttggagacgg aatttttcca aacggattcg gcgcgatctt tatcacgatg atcaccgtca
    24721 actttgcctt tcaggggacg gagctgatcg ggatcgcggc gggggaaagc gaaaatccgg
    24781 aaaaaacggt gccccgctcc atcaaacaga cggtctggcg gacactggtg tttttcggcc
    24841 tgtccgtatt tgtactggcg ggattgattc catgggaaaa agcgggggtt gttgaaagtc
    24901 cgttcgttgt ggtatttgaa caaatcggca ttccgtatgc cgccgatctg atgaactttg
    24961 ttattttaat tgctttgtta tcggtggcga attcgggctt gtacgcatcg acgaggatgc
    25021 tttattccct ggcgaaagag ggaatggccg ctcaggcttt aagccgggtc aataaaagag
    25081 gtattccgat gaatgcgctt tggatcacgc tcggttttgc gggtttgtcc ctcatctcaa
    25141 gcgtagtcgc agcagaaacg ctctacattt ggcttttgtc tctagccggt ttaagcgcgc
    25201 aagtcggctg gatcacgatt acggtatcac agctgctatt tcgcagacga tatgtcaaag
    25261 aaggcggaaa ggttgaagac ttaaaattta aaacgcctct ttatccttat ttgccgctga
    25321 cgggatttat tttaaacagc gccgtccttg tgagcctcgc ttttgattca gagcagagga
    25381 tggcattgta ctgcgggatt ttattcatgt cggcctgcta ctttgtttat cacgtgtttg
    25441 tgaaaaaacg ccaggctctt gatcgacaag aagcaatgat ctatcaaaac aaaacaaacg
    25501 atgaggtggt tattgatgaa taaacaagtt tctttgatt
//
