LOCUS       NZ_LQYL01000021        22734 bp    DNA     linear   CON 26-JAN-2024
DEFINITION  Bacillus licheniformis strain B4090_201601 NODE_34, whole genome
            shotgun sequence.
ACCESSION   NZ_LQYL01000021
VERSION     NZ_LQYL01000021.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus licheniformis
  ORGANISM  Bacillus licheniformis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 681005)
  AUTHORS   Krawczyk,A.O., de Jong,A., Holsappel,S., Eijlander,R.T., van
            Heel,A., Berendsen,E.M., Wells-Bennik,M.H. and Kuipers,O.P.
  TITLE     Genome Sequences of 12 Spore-Forming Bacillus Species, Comprising
            Bacillus coagulans, Bacillus licheniformis, Bacillus
            amyloliquefaciens, Bacillus sporothermodurans, and Bacillus
            vallismortis, Isolated from Foods
  JOURNAL   Genome Announc 4 (3), e00103-16 (2016)
   PUBMED   27174261
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 681005)
  AUTHORS   Berendsen,E.M., Wells-Bennik,M.H., Krawcyk,A.O., De Jong,A.,
            Holsappel,S., Eijlander,R.T. and Kuipers,O.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JAN-2016) Molecular Genetics, University of Groningen,
            Nijenborgh 7, Groningen, Groningen 9747AG, the Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2015
            Assembly Method                   :: Velvet v. 1.2.10
            Assembly Name                     :: B4090
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/26/2024 01:23:23
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,545
            CDSs (total)                      :: 4,463
            Genes (coding)                    :: 4,342
            CDSs (with protein)               :: 4,342
            Genes (RNA)                       :: 82
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 121
            CDSs (without protein)            :: 121
            Pseudo Genes (ambiguous residues) :: 0 of 121
            Pseudo Genes (frameshifted)       :: 68 of 121
            Pseudo Genes (incomplete)         :: 58 of 121
            Pseudo Genes (internal stop)      :: 20 of 121
            Pseudo Genes (multiple problems)  :: 22 of 121
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:24:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 326637
            Orig. end                         :: 349371
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LQYL01000021.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22734
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="2"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22734
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22734
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12734](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12734)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            complement(998..2182)
                     /locus_tag="B4090_RS08360"
                     /old_locus_tag="B4090_4348"
     CDS             complement(998..2182)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186169.1"
                     /locus_tag="B4090_RS08360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_4348"
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="WP_025805366.1"
                     /transl_table=11
                     /translation="MSQKKNITNPFYQGDLIFVYIVFFIISVVAVYAAQQFNQYNEPFA
                     MKQCLYYLLGAFIIIVFLYFDLEQLEKLSFYFYLLGILMLIVLKFSPAYIGSYRFAPVI
                     NGAKSWFMLPGFTLQPSEFMKIGLIMYLASFMSKNGPVGKRTLKEDWIFLLKIAGIIIV
                     PFGLILEQDTGTAGIVAFVILVMVFLSGVNWKLISLIFGTGLAAVALILYVIIKFPDVA
                     GALGVEQYQINRVMTWVNPSEQNADDKMQVERAQMAIGSGKVFGNGVSDLQVYVPEAQT
                     DFIFAVIGESFGFVGCTFVVIMFFFLIYRLVVLIDRIHPFSRFASFFCAGFTALIVIHT
                     FQNIGMNIGIMPVTGVPLLLVSYGGSSVVATLLGFAVVYNSSCQLTKYQSYMFK"
     gene            2461..3816
                     /locus_tag="B4090_RS08365"
                     /old_locus_tag="B4090_4350"
     CDS             2461..3816
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017474081.1"
                     /locus_tag="B4090_RS08365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_4350"
                     /product="YjiH family protein"
                     /protein_id="WP_061576505.1"
                     /transl_table=11
                     /translation="MDKALQKRKRLDIIKFLVPSLIGIILFMIPVKIEGNLTIPIAVFS
                     NALQELLQQQLPLIMTVIVTATFILTFITKTFHPAFIKKSEFFYNLLNVSLFWYIVRLV
                     GMIFTVMAYFKIGPEAVYAKSTGGTLLFSLLPVLFSVFLFAGLFLPFLLNFGLLELCGA
                     LMKNLMRPVFKLPGRSSIDCMASWLGDGTIGVLLTSKQYEEGFYTKREAAVIGTTFSVV
                     SITFCLVIISQVGLPHMFVPFYLTILLAGAAAAVISPRIPPLSRKADTYITDQADQDQE
                     KIPEGYTPFQWGLSQAVAKAKQNTSVKDFLQDGAKNVLDMWMGVAPVVMALGTAALIVA
                     EYTPVFKWLGLPFIPLLELLQVPEAAEASQTLVVGFADMFLPSVLGSGIESEMTRFIIA
                     CVSVTQLIYMSEVGGLLLGSKIPVTFLDLVLIFLVRTLITLPVIVLCAHFIF"
     misc_feature    4088..4102
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.12"
                     /tool="antismash"
     misc_feature    4089..4100
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.15"
                     /tool="antismash"
     misc_feature    4202..4216
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.52"
                     /tool="antismash"
     gene            4239..4499
                     /gene="ywcE"
                     /locus_tag="B4090_RS08375"
                     /old_locus_tag="B4090_4352"
     CDS             4239..4499
                     /codon_start=1
                     /gene="ywcE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186174.1"
                     /locus_tag="B4090_RS08375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_4352"
                     /product="spore morphogenesis/germination protein YwcE"
                     /protein_id="WP_003186174.1"
                     /transl_table=11
                     /translation="MDMFFAYLLIASATPLFLWLDNKKVAISSIPPIILMWVFFFFYMT
                     SSLSPTGHSLMIALFILNVVIAHVAAFIIYGLPLIRKHMSR"
     gene            complement(4547..5746)
                     /locus_tag="B4090_RS08380"
                     /old_locus_tag="B4090_4353"
     CDS             complement(4547..5746)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011198409.1"
                     /locus_tag="B4090_RS08380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_4353"
                     /product="clostripain-related cysteine peptidase"
                     /protein_id="WP_061576507.1"
                     /transl_table=11
                     /translation="MNLIKWILFSVISFAFFQPAPAALLKEKDDYTILVYMIGSEMESD
                     FHMASDDIQEMMDAGSSSNVNVVLQTGGAKKWANPSISHKVNQRWKVEHQKLVPLENVG
                     KKNMDSPGSVTDFITWGVKTYPAKKYVLIFWGHGLGSVDGYGGDENFGNKKMKISELQL
                     GIKTAYEHTKQKFDLIGFDNCKMAGIETAYALRDYGKYMLASVDYTNQNGWDYKRALQS
                     VQDDPSIDPKELGREIAAGYVQQSKENGETEDLQQSLIQLNRVKDAVDALDRLSVNMNL
                     ALKEPDGKRLLHYARLAAEDYADESDMVDLADLSSLIGQQIGAEKEAKEVVKSVKKAVI
                     MNIKSPEHPRGSGMSVYYPARDNHKRFAEKSKIYRLLDFSSRYQTFIKDYSHSTFNFDL
                     "
     gene            complement(5764..6219)
                     /locus_tag="B4090_RS08385"
                     /old_locus_tag="B4090_4354"
     CDS             complement(5764..6219)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186178.1"
                     /locus_tag="B4090_RS08385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_4354"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_003186178.1"
                     /transl_table=11
                     /translation="MSNIEELRLFRKEDIEWLQTWFEDAEVKRRLEGMLPLDEWFNFAG
                     GNENYRVWAALEDGKPVGVVMVEVEEDLTGNIALLVDPFLRGGGYGKALIKRTMALPEM
                     SRINKWFAGIEEDNKRCLACFRSVGYSLEHEQPDEDCYYSLIYFPES"
     gene            complement(6231..8039)
                     /locus_tag="B4090_RS08390"
                     /old_locus_tag="B4090_4355"
     CDS             complement(6231..8039)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186181.1"
                     /locus_tag="B4090_RS08390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_4355"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_061576508.1"
                     /transl_table=11
                     /translation="MLKFYSFFKKLPQTASIIFYGLTLFWRCDPFKSAVLFLITLLNAM
                     LGPLLVWLSAEVIDEIARAPFELSSWNALVWAAFAYIAFTLIVDALQPVAEMQKRLLTA
                     KLEAYLDEMLMKKAISIPDIAAFEDASFHTNTQIIRYNEYFVTMWVSIVSQTFGGMVMI
                     AASSLLIGMAAPWVPLLFLILAVPKLYWEAKLNNATFEGRKEVQELRRRAEYYAGVPLM
                     SETAGEVKIYNLVPFFKSFYKNTSMELLHTLSNDQKKLALYQLFWSVLQSLAAGAVLIY
                     IVHQAFHGGLSIGDVMLFIGAAVQFNEGINEMFAAFAIGARETRHLGNVHSFLNSKNSM
                     ENGETAPAVQKQKGFTCDQVEFSYDGTKTVLDIQQLDIPLNKTTVLVGENGSGKSTLVK
                     LLLRYFDPNQGTISYNGLPLYKYDIEHYRSNAAAVFQDFLRYEMTLKYNIGLGDISSCT
                     DLAKIKSASAFGGVDQFLHKLEDGYETELGRLFGGRNLSGGEWQRIAISRAFMRDECAD
                     ILIFDEPSSALDVFIEEEIFDKLQKLTQGKTVIIVSHRLSTARFADHIIFLEKGRVAEA
                     GTHQELMKNQAQYAELYRLQAEKYAQ"
     gene            complement(8033..9958)
                     /locus_tag="B4090_RS08395"
                     /old_locus_tag="B4090_4356"
     CDS             complement(8033..9958)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009329820.1"
                     /locus_tag="B4090_RS08395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_4356"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_235598169.1"
                     /transl_table=11
                     /translation="MKHIQEPLQTAGLLGKMVWKSGPRLMICMVIFMLIEAGAPLIQLY
                     VSKQMIDGIVDQEAVIYAEIWAVIYAGSLVMVSVVKSLEKWVKAMLSERSMITVNSLLI
                     DAFDRIPGMRFFEDPKYRDRLETLRDRSTWLPSQFINISSNLVTAVMSLAGVVLIIAYL
                     SPVLAFILILSTAPFAFVHNHYNEMEWEYHKDYAPVRRRAAYARHILLGRRSAKEVRLF
                     GLGSFFLDLYQSAFKGLYSVLRNIQVRSARWSVLTGFLSGAGTGLGYFWILSQSHSSSF
                     SVGDISLYLGAVFQLSTALRDIAKEGADTLDIWRMGRDFFLFMNAEKDIRLPSNGESLE
                     GEGPLAVEFKNVTFRYPFREAAAGSRVNEADVDEEDLDMLDELEDEEMRGQDEQPESYD
                     MHTGDVLNRISFSVSPGERIAIVGANGSGKTTLIKLLCRFYEYDEGEIKVNGKDIRNVD
                     LQQLRNKMAVVFQEFGRYELSLRHNIAIGRTEALGDEEKLRAAARAAKLEPIVEELPEG
                     LETIIGPEWGGTDFSGGQWQRIALARSFMKDAGLVILDEPAASLDIRAEYDIFRQFQSF
                     TEGKTVIMISHRFSTVKMADRILVLKNGRIAEEGSHQELMDKNGEYSRMFRMQAKSFQG
                     KDEVYC"
     gene            complement(10001..12001)
                     /locus_tag="B4090_RS08400"
                     /old_locus_tag="B4090_4357"
     CDS             complement(10001..12001)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017474082.1"
                     /locus_tag="B4090_RS08400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_4357"
                     /product="asparagine synthetase B family protein"
                     /protein_id="WP_003186185.1"
                     /sec_met_domain="Asn_synthase (E-value: 8e-24, bitscore:
                     80.3, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIWFGMQGNNTALWQEWVSAVKKWGRAERIHSYSCGIANMAEAH
                     IRYDEAFRPSTQINLLHPVILDGWISGGLNAKSDGTRKIEQYDKLYASLKQDKAAMLSH
                     SHGEYTMVWWDDSLHSLVLATDTYATRPVYYWVSPKGEWYAANDMRILLLVHDIPFAID
                     QDVCRMFPTSGFAVGENGFEDRTFFKGIRKVPAASYAFLGRDQAVHVHSYWGLPQLLNE
                     KDLAGDAVPRFRELFQEVTADRLKDERHIVELSGGLDSAAVTAAAVAGGRKEQLLAVNI
                     SFAEPDMILSHDRDLVKNMMRDMDIPGLIILGDATAKIPNAEIGRDPLWFVDGPDPRAN
                     SLVNETFTVIAEEYGASSVLTGEGGDFIFSGEVSVIDSLLRQRRFSEIYKLLREWSGGS
                     MKEMLKLGFQYGIAPFMPYIGEKLYYDLLWSDTEYELPEYFTEEHRKREWEINKEDHLR
                     YRKSRELSVWGKRFHYDFLWPRARYMDAVGVTLHTYHPFLDRRLIEFSFSVPPEQHFDV
                     LKGLEEHYAGSKMLLRKSFTDILPAYVYNRSTKTTYAHMARKSFMNDRRHVLQLFEPGE
                     RVFVEELGIIKRDIWWKHLLAMAIRSEDPNNDLGMGYQYMRSVIDLEIWLREASKGKEH
                     LLDRSRPVKPRVMADIETVNTPEKAKIYSYQ"
     gene            complement(11998..12462)
                     /locus_tag="B4090_RS08405"
                     /old_locus_tag="B4090_4358"
     CDS             complement(11998..12462)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186187.1"
                     /locus_tag="B4090_RS08405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_4358"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_009329822.1"
                     /sec_met_domain="PF13471 (E-value: 5e-15, bitscore: 50.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKRALVKNHEYFTTVHAFVRMMLLNYDFEEAYEKIAIHLFPLYA
                     SAKQRGAGLLDIDELHRNGEYLYSLDEDDHLVTSCVSIALTIQSILFSNGSDADLMIGV
                     KKIDDKLFSHAWVQMENGKSIDPNHKNKNLKVLQTYKMSAYAERWVLSLV"
     gene            complement(12462..12734)
                     /locus_tag="B4090_RS08410"
                     /old_locus_tag="B4090_4359"
     CDS             complement(12462..12734)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186189.1"
                     /locus_tag="B4090_RS08410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_4359"
                     /product="hypothetical protein"
                     /protein_id="WP_003186189.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.7e-09,
                     bitscore: 32.3, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIIRNQETATTVLENECIVLNLDNGQYFGLEGALKELWIEIENE
                     RKDKKDILIKWQSAFDQTEEELSAILNEAIQELTHHKLIKIEDKS"
     aSDomain        complement(12477..12722)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_B4090_RS08410_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.10E-10"
                     /identifier="RREFam002.1"
                     /label="B4090_RS08410"
                     /locus_tag="B4090_RS08410"
                     /protein_end="86"
                     /protein_start="4"
                     /score="32.3"
                     /tool="antismash"
                     /translation="RNQETATTVLENECIVLNLDNGQYFGLEGALKELWIEIENERKDK
                     KDILIKWQSAFDQTEEELSAILNEAIQELTHHKLIKI"
     misc_feature    12717..12735
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.74"
                     /tool="antismash"
     CDS             12753..12866
                     /gene="allorf_339390_339503"
                     /locus_tag="allorf_339390_339503"
                     /protein_id="allorf_339390_339503"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MHDFRKIKEKRAGKLSFSTLCMMFFPRPRYHFSAGAF"
     CDS_motif       12753..12812
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MHDFRKIKEKRAGKLSFSTL"
                     /locus_tag="allorf_339390_339503_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       12813..12866
                     /prepeptide="core"
                     /locus_tag="allorf_339390_339503_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-7.70"
                     /molecular_weight="2047.4"
                     /monoisotopic_mass="2045.9"
                     /core_sequence="CMMFFPRPRYHFSAGAF"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MHDFRKIKEKRAGKLSFSTL"
                     /leader_location="[12752:12812](+)"
     gene            complement(13084..13716)
                     /locus_tag="B4090_RS08415"
                     /old_locus_tag="B4090_4360"
     CDS             complement(13084..13716)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186191.1"
                     /locus_tag="B4090_RS08415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_4360"
                     /product="response regulator transcription factor"
                     /protein_id="WP_003186191.1"
                     /transl_table=11
                     /translation="MIRVLLVDDYRVLTSGMKEILKKYNMDVIVCHEGNEALDLLKNQE
                     VHIDVFLYDLKMPGMNGLELSLKTLEIEPQSKIIIMFSGDEIHSYFNKLIEAGVKGFID
                     KSYTDSMIASSILLCLKGAVLFPDGLLQKLRLDSDLSVDEHLTDTELDILQKVASGKTN
                     KEIAADLQMSTRNVEYHLSKIYKKLKVTSRYCAVKKGTMLNLIKQKV"
     CDS             13879..14004
                     /gene="allorf_340516_340641"
                     /locus_tag="allorf_340516_340641"
                     /protein_id="allorf_340516_340641"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTQMRKLESAQVKSYGSFLTVTLSKKSKPGDGKFGRGVKRG"
     CDS_motif       13879..13947
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MTQMRKLESAQVKSYGSFLTVTL"
                     /locus_tag="allorf_340516_340641_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       13948..14004
                     /prepeptide="core"
                     /locus_tag="allorf_340516_340641_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-6.40"
                     /molecular_weight="1871.1"
                     /monoisotopic_mass="1870.1"
                     /core_sequence="SKKSKPGDGKFGRGVKRG"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MTQMRKLESAQVKSYGSFLTVTL"
                     /leader_location="[13878:13947](+)"
     gene            complement(14104..14469)
                     /gene="qoxD"
                     /locus_tag="B4090_RS08420"
                     /old_locus_tag="B4090_4362"
     CDS             complement(14104..14469)
                     /GO_function="GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0016682 - oxidoreductase activity, acting
                     on diphenols and related substances as donors, oxygen as
                     acceptor [Evidence IEA]"
                     /GO_process="GO:0015990 - electron transport coupled proton
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="qoxD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006639513.1"
                     /locus_tag="B4090_RS08420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_4362"
                     /product="cytochrome aa3 quinol oxidase subunit IV"
                     /protein_id="WP_003186195.1"
                     /transl_table=11
                     /translation="MAAKQSAEHSHFPWKHIVGFVLSIVLTLLALWVIYTDLSMAAKLW
                     IIFGFAIIQAGLQLLMFMHMTESDSGKIQVGNTLFAAFIAVAIIAGSVWIFAAHNYHGD
                     NPEGGSPGAKHSEHSGH"
     gene            complement(14469..15083)
                     /gene="qoxC"
                     /locus_tag="B4090_RS08425"
                     /old_locus_tag="B4090_4363"
     CDS             complement(14469..15083)
                     /GO_function="GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0016682 - oxidoreductase activity, acting
                     on diphenols and related substances as donors, oxygen as
                     acceptor [Evidence IEA]"
                     /GO_process="GO:0015990 - electron transport coupled proton
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="qoxC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391694.1"
                     /locus_tag="B4090_RS08425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_4363"
                     /product="cytochrome aa3 quinol oxidase subunit III"
                     /protein_id="WP_003186197.1"
                     /transl_table=11
                     /translation="MEHAEHSNSNAPMEYRSEIGRLNILGFWIFLGAEIALFSTLFATY
                     AVLHNRTAGGVLPAELFDAKLVLIMTFLLLTSSFTCGIAVHEMRRGSLKGVMIWMIITL
                     LLGAGFVSYELYEFNHYVHEGATLSTSAYWSAFFVLLGTHGLHVSIGIFWIIGILLQTK
                     KRGLTPQTSAKLFISSLYWHFLDVVWIFIFTGVYLIGLVNV"
     gene            complement(15098..17047)
                     /gene="qoxB"
                     /locus_tag="B4090_RS08430"
                     /old_locus_tag="B4090_4364"
     CDS             complement(15098..17047)
                     /GO_function="GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0015990 - electron transport coupled proton
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="qoxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391695.1"
                     /locus_tag="B4090_RS08430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_4364"
                     /product="cytochrome aa3 quinol oxidase subunit I"
                     /protein_id="WP_003186199.1"
                     /transl_table=11
                     /translation="MNLKWDEFIITGDPLILGAQISILLTSIAIVFVLTYFKKWKWLWR
                     EWITTVDHKRLGIMYIIAAVIMFFRGGVDGLMMRAQLTLPNNGFLDSNHYNEVFTTHGT
                     IMIIFMAMPFLIGLMNVVVPLQIGARDVAYPYLNNLSFWTFMVGAMLFNISFVIGGSPN
                     AGWTAYMPLAGNELSPGPGQNYYLLGLQIAGIGTLLTGINFMVTILKMRTKGMTLWRMP
                     MFTWTTLITCVIIIFAFPVLTVALALMTFDRLFGTAFFTLANGGMPMLWANLFWIWGHP
                     EVYIVILPAFGIFSEIIATFARKQLFGYKAMVYSIVAISVLSFIVWLHHFFTMGNSAAV
                     NSFFSITTMAISVPTGVKIFNWLLTLHRGRIKITTPMLWSLAFIPNFVIGGVTGVMLAM
                     AAADYQYHNTYFLVSHFHYVLIAGTVFACFAGLIFWYPKMFGHKLNERIGKWFFWLFMT
                     GFNICFFPMYFLGLQGMPRRIYTYGAEDGWTALNMIATFGALLMAAGFIVLCYNIFYSF
                     RHSKREESGDAWGMGRTLEWATSSAIPPHYNFAVLPEVTSPDAFAQMKEDNVEIHPESK
                     FKKIHMPSNSGRPFIMSLCFGFAGFGLVFEWFWMGIVGLIGVFLCMILRSFEYDDGYYV
                     SVEEIKETERKNAK"
     gene            complement(17065..18033)
                     /gene="qoxA"
                     /locus_tag="B4090_RS08435"
                     /old_locus_tag="B4090_4365"
     CDS             complement(17065..18033)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0016682 - oxidoreductase activity, acting
                     on diphenols and related substances as donors, oxygen as
                     acceptor [Evidence IEA]"
                     /GO_process="GO:0015990 - electron transport coupled proton
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="qoxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186201.1"
                     /locus_tag="B4090_RS08435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_4365"
                     /product="cytochrome aa3 quinol oxidase subunit II"
                     /protein_id="WP_003186201.1"
                     /transl_table=11
                     /translation="MILLFRAFKPLIMLTLLSSVFLLGGCSQIAVLDPKGPVASQQRDL
                     ILLSIGFMLFIVAVVFVLFTVMIVKYRERKDRKSPYSPEVEGNTFLEIVWTVVPILIVI
                     ALSVPTVQTIYSLEEAPKASKDKEPLVVYATSVDWKWVFSYPEQDIETVNYLNIPTDRP
                     ILFKISSADSMASLWIPQLGGQKYAMSGMEMEQYLQADHEGTYKGRNANFTGEGFAEQK
                     FNVNAVSESKFNDWVKKTQKEAPKLTKTQYDELMLPQHADEMTFSSTHLKYVNHGNDAE
                     YAIKARERLGYKPLSPHSKSDPFENVKTNKDQKQSEDQDSH"
     misc_feature    18161..18176
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: strong, score: 27.5"
                     /tool="antismash"
     misc_feature    complement(18183..18198)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.79"
                     /tool="antismash"
     misc_feature    18373..18388
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.83"
                     /tool="antismash"
     gene            complement(18505..19494)
                     /gene="galE"
                     /locus_tag="B4090_RS08440"
                     /old_locus_tag="B4090_4366"
     CDS             complement(18505..19494)
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (64-191). E-value:
                     1.2e-11. Score: 36.2. Matches aSDomain:
                     nrpspksdomains_B4090_RS08440_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186203.1"
                     /locus_tag="B4090_RS08440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_4366"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_003186203.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.7e-17, bitscore:
                     58.1, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 9.5e-15,
                     bitscore: 49.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAILVCGGAGYIGSHAVAELLSRNEDVVIIDNLQTGHEEAALKGA
                     SFYNGDLRDEAFLRKVFQENDIEAVMHFAADSLVGESVTDPLKYYDNNVYGAVCLLKVM
                     KEFDVKQIVFSSTAATYGEPDRVPIMETDPTDPTNPYGETKLAIEKMLKWSEKAYGIRH
                     VVLRYFNVAGAHVDGLIGEDHQPETHLIPIILQVALGKRDKIMIFGDDYPTPDGTCIRD
                     YIHVMDLVDAHILAVERLRNGGESAVYNLGNGTGFSVKEVVETARKVTGCPIPAEVAER
                     RAGDPAQLIASSEKAVKELGWQPKYAELETIIDSAWKWFKAHPNGYQS"
     aSDomain        complement(18922..19302)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B4090_RS08440_NAD_binding_4.1"
                     /evalue="1.20E-11"
                     /label="B4090_RS08440_NAD_binding_4.1"
                     /locus_tag="B4090_RS08440"
                     /protein_end="191"
                     /protein_start="64"
                     /score="36.2"
                     /tool="antismash"
                     /translation="NDIEAVMHFAADSLVGESVTDPLKYYDNNVYGAVCLLKVMKEFDV
                     KQIVFSSTAATYGEPDRVPIMETDPTDPTNPYGETKLAIEKMLKWSEKAYGIRHVVLRY
                     FNVAGAHVDGLIGEDHQPETHLI"
     misc_feature    complement(19525..19538)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.22"
                     /tool="antismash"
     misc_feature    19553..19567
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.24"
                     /tool="antismash"
     misc_feature    19718..19731
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.28"
                     /tool="antismash"
     gene            20296..20445
                     /locus_tag="B4090_RS08445"
                     /old_locus_tag="B4090_4369"
     CDS             20296..20445
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186207.1"
                     /locus_tag="B4090_RS08445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_4369"
                     /product="anti-repressor SinI family protein"
                     /protein_id="WP_003186207.1"
                     /transl_table=11
                     /translation="MNTQTKHKLDKDWVILMKEAKKLGLQIEDVKEFLRSQPIQSDAEK
                     QIKQ"
     gene            20987..21608
                     /locus_tag="B4090_RS22980"
                     /pseudo=""
     CDS             20987..21608
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009329825.1"
                     /locus_tag="B4090_RS22980"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="flavodoxin family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGIAAICGSSRENGNTEELVNRLGRRT"
     gene            21727..22041
                     /locus_tag="B4090_RS08460"
                     /old_locus_tag="B4090_4372"
     CDS             21727..22041
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003186216.1"
                     /locus_tag="B4090_RS08460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B4090_4372"
                     /product="DUF485 domain-containing protein"
                     /protein_id="WP_003186216.1"
                     /transl_table=11
                     /translation="MGEGKIDYSKAAASPEFQRLLKRKRAFIVPMTIFFLLFYFLLPVM
                     TSYFTFLNQPAVGAITWAWVFAIAQFVMTWTLCIVYTKKAGQFDQIASDFKKKIGGVDS
                     "
ORIGIN
        1 cgacaaatgt acagccgata aagccgaaac tttcgccgat gacggcatag atgaaatcgg
       61 tttggccttc aggaacgtat actttcaaat tgttaatgcc cgttccgaag atttctcctg
      121 agccgatcgc cgtaacagct ttttcggtct gatacgtatc attcgcgtcc tgctggctcg
      181 aatcgaccca tgtcatcacc cggttgatct gatattgctg gatatgcaat gtatcctttg
      241 aaaactccgg aaaattgatc accaaaaaca gaacgagcag tacgagcgtg atgcccgatc
      301 ccgcgactat gaaaatcagc ttccagttca cgcctgataa aaacaccata acggcgacaa
      361 agaacatgca gataccggcc gtaccggcgt cctgcattaa aatcaatccg accggaaccg
      421 ccgacactcc cgcgattttc agcaacaggc gaacatcctc ctgcatcgag cgcgagcctt
      481 tcggacttgc tttggaaatc accgaagcca gcatcataat caggccgatt ttcataaatt
      541 ccgacggctg cagcgtgatc gtaccaaatt gaaaccagct ttttgcgccg tttttaatcg
      601 gagcgatcga ctccggacta acttttaaca cgagcaacga caagatgccg aataaatata
      661 tgtaaatgct taacttttca agctgctcca gatcaaaata gagaaagccg acgatcaccg
      721 aaatgccgag cagataaaag aacaattgct ttgccggata acccttcggt gaaaaagacg
      781 gctccgcagc gtaaacagcg atcacactga ttaaaaagaa catggctaat ataaaaatca
      841 aatcgccctg ataataggga cttgtcgtat ttttcttctg gcccattata ccccgcctta
      901 tttcttcatc aaaagcacta actttcatta tagcatgaac aaccgttcac attgcgaaaa
      961 agggtgaata aaataacagc ccgcatacat caggctgtta tttgaacata tagctttgat
     1021 actttgttaa ctggcagctt gaattgtaga caaccgcgaa gccgagcaag gttgctacga
     1081 ctgagctgcc tccatagctg accaaaagca gcgggacgcc ggtcacgggc ataatgccga
     1141 tattcattcc gatattttga aaggtatgaa tgacaattaa agcggtaaag cccgcacaga
     1201 aaaatgaggc aaacctgctg aacggatgta ttcggtcgat gagcacgaca agccggtaaa
     1261 ttaagaagaa aaacataatg acaacaaaag tgcatccgac aaacccgaag ctctcgccga
     1321 tgacggcaaa aataaagtct gtttgcgcct caggtacata gacttgaaga tcgcttacac
     1381 catttccgaa tacttttcct gaaccgatcg ccatttgcgc cctttcgacc tgcattttat
     1441 cgtcggcatt ctgttcgctc ggattgaccc aggtcataac gcggttgatt tggtattgtt
     1501 caaccccgag cgctcccgca acatcgggaa atttgatgat gacatataaa atcaaagcaa
     1561 cggctgcaag acccgttccg aagataagag aaatcaattt ccagttcacg cccgacagga
     1621 ataccatcac aaggatcaca aacgcgacga tcccggctgt acccgtatcc tgctctaaaa
     1681 tcaagccgaa cggaacaatg atgataccgg cgattttcag cagaaaaatc cagtcttctt
     1741 tcaacgtacg cttgccgaca gggccgtttt tagacatgaa ggaagccaag tacatgatca
     1801 gcccgatttt cataaattcc gacggctgca gcgtaaaccc gggaagcata aaccagcttt
     1861 tggcaccgtt gatgaccggc gcaaacctgt atgatccgat atatgccgga ctgaacttta
     1921 acacgatcag catcaaaatg ccgagcagat agaaataaaa gctgagcttt tcaagctgct
     1981 ccaaatcaaa ataaagaaac acgatgatga tgaaggcccc cagtaaatag taaaggcact
     2041 gtttcatcgc aaagggttca ttatattgat taaactgctg agcagcgtac acagccacaa
     2101 cgcttatgat aaaaaagaca atatagacaa aaatcaaatc cccctggtaa aagggatttg
     2161 taatattctt tttctgactc attcgaaatc ccgcccttat aatatgacac aatgaattaa
     2221 tgcaggaaga cggcatccgc ttcctcacaa atgatatgac gtacaaaaga acaaaatgtt
     2281 tcgattttat tgcgaacaaa ttcctattct attttaaagg atttttccaa ctattgtcga
     2341 atgtgataaa ttcattgatt tttgcttgaa atgtattaaa atgagtaatg ttgcataaaa
     2401 ttaaactttt gcctccggca gaagtggtac agaatcacca attcataagg agtttttcat
     2461 ttggataaag cacttcaaaa gcgtaaacgg cttgatatca taaaattttt ggtcccttcg
     2521 cttatcggaa ttattctgtt tatgattccc gttaaaattg aaggaaattt aacgattcca
     2581 attgctgttt tttcaaatgc attgcaggag ctgcttcagc agcaattgcc gctgatcatg
     2641 acggtcatcg taaccgcaac atttatctta acctttatca ccaaaacctt tcatccggct
     2701 ttcatcaaaa aaagcgagtt tttctataac ctgctgaatg tatctttatt ttggtatatc
     2761 gtccgcctag tcggcatgat tttcaccgtg atggcgtact ttaagatcgg acctgaagcg
     2821 gtgtatgcca agagtaccgg cggaacatta ttattcagcc tgcttcccgt tctcttctcc
     2881 gtctttctat ttgcaggcct ttttctgccg tttctgttga atttcggctt gctcgaactg
     2941 tgcggcgctt tgatgaaaaa cctgatgagg cctgtcttta agctgccggg gcggtcatcg
     3001 atcgattgta tggcttcatg gctcggcgac ggcacgatcg gcgtgctcct gacgagcaaa
     3061 cagtatgaag aaggattcta cacgaagcgt gaggccgccg tcatcggcac gactttctca
     3121 gtcgtctcca tcacgttttg cctcgtgatt atttcacagg ttggccttcc tcatatgttc
     3181 gttccgtttt atttgacgat attgctggcg ggtgccgcag ctgcggtgat cagcccgcgg
     3241 attccgcctt tatcaagaaa ggctgatact tatattacag atcaagcgga tcaggatcaa
     3301 gagaagattc ccgaaggata cactccgttc caatgggggc tcagccaggc tgtcgcaaaa
     3361 gcaaaacaaa atacaagcgt caaagatttc ttgcaggacg gggctaaaaa cgtactcgat
     3421 atgtggatgg gcgtcgctcc cgtcgtcatg gcgctcggca cagccgcgct gattgtcgct
     3481 gaatatacgc cggttttcaa atggcttgga ctgccgttca ttcctcttct cgagctgctg
     3541 caggttcctg aagccgctga ggcctcacaa acgcttgtcg tcgggtttgc cgacatgttc
     3601 ctaccgtccg tgctcggaag cggcattgaa agtgaaatga ccaggttcat catcgcctgt
     3661 gtatcggtta cacaattaat ctacatgtcc gaagtcggcg gccttttgct aggttccaaa
     3721 atcccggtga cgttccttga cctcgtcttg atttttctcg ttcggacgct tattacgctg
     3781 cctgtcattg tactgtgtgc ccactttatt ttttagacaa ataaaaggct cccggcgcca
     3841 aatgccgagg gccttttttg tttagaaaaa aatcgttgat ccaaggggtc tgcggcctta
     3901 tcggacgatc cgcctgtccg cttcttcgct tcccgtaagc ctgccggcct cgtataggaa
     3961 acgcgcggtt cttggctaac tttcgcatga tcaatctcct ccacgcattt tcgctattca
     4021 cttcttctcc ccttcaccct ttatgtccta actgaatcac cgtgaaaatt gagccgatag
     4081 ttggagcgga aaatgctttc cagtatgtat catttttcga aaaacgtggt ataataaatg
     4141 taacagaatg ttcacaaaat attctccaat tagacacaat tgatgtttca ttccgctttt
     4201 ttgacagcgc tatcattatc gaaaggggct gaaaacgcat ggatatgttt ttcgcttact
     4261 tgctgattgc aagcgccact cctttatttt tatggttgga caacaaaaag gtcgcaattt
     4321 cttctattcc gcccatcatt ttaatgtggg tattcttctt tttctatatg accagcagcc
     4381 tttctcctac aggacactct ctcatgatcg cactctttat tctcaacgtt gtcatcgccc
     4441 atgtcgccgc tttcatcatc tacggacttc cattgatccg gaagcacatg agccgataaa
     4501 aaaagtgccg gtttttccgc cggcgctttt ttgctgttaa acgcaactat agatcaaagt
     4561 taaatgttga atgcgagtaa tctttgatga atgtttgata ccggctgctg aagtcaagca
     4621 ggcggtatat tttcgatttt tccgcaaacc gcttatggtt gtctctggcc ggataataaa
     4681 cggacatgcc gcttcctctt gggtgctccg gagatttgat gttcatgatg acagccttct
     4741 tgacggattt tacgacctct tttgcttctt tctcggctcc gatctgctga ccgatcaagc
     4801 ttgacaaatc cgccaaatca accatatccg attcatctgc ataatcttca gcagcgagac
     4861 gcgcgtagtg gagcaggcgc tttccgtcag gctctttcaa tgccaggttc atgtttacgc
     4921 tcaatctgtc gagggcatcg acagcgtctt tgacacggtt caattgaatt aaagactgct
     4981 gcaggtcttc tgtttcaccg ttttcttttg actgctgtac gtagcctgca gcgatttccc
     5041 tgccaagctc tttcggatcg attgaagggt cgtcttgtac agactgcagc gcccttttat
     5101 aatcccagcc gttttgattc gtatagtcga ctgaagccag catgtactta ccataatccc
     5161 tcaaggcata tgccgtttca atcccggcca ttttgcagtt gtcaaaaccg attaaatcaa
     5221 acttttgctt cgtatgttca taggccgttt tgattcccaa ctgcagctcg cttattttca
     5281 ttttcttatt gccgaagttt tcgtctcccc cgtagccgtc aactgagcca agcccatgcc
     5341 cccaaaagat caatacatat tttttagccg gatatgtttt gactccccat gtgataaaat
     5401 ctgtgacgga gccgggactg tccatatttt tcttcccgac attttcgagg ggcaccagct
     5461 tctgatgttc aactttccac ctctgattca ccttgtgact gatcgacggg ttcgcccatt
     5521 tttttgctcc tcctgtctga agaacgacat tgacgtttga agatgaaccc gcatccatca
     5581 tttcctgaat gtcatcgctt gccatatgaa aatcgctttc catttcagaa ccaatcatat
     5641 aaacaagaat agtatagtcg tccttttctt ttaatagagc ggctggtgcc ggctgaaaaa
     5701 aggcgaatga aataacggaa aacaaaatcc atttgatcaa gttcatcttc ttatgctcct
     5761 tatttaagat tccgggaaat aaataagaga gtagtagcag tcttcgtccg gctgttcgtg
     5821 ttccaatgaa tacccgacgg atcggaagca cgctaagcac ctcttgttat cctcttcaat
     5881 tccggcgaac catttgttga tccggctcat ttccggcaat gccatcgtcc ttttgatgag
     5941 cgcttttcca tatccccctc cgcgcaaaaa cggatcgact aaaagggcaa tgttcccggt
     6001 caagtcctcc tcaacttcaa ccatgacaac gccgacaggc ttgccgtcct ctaaagccgc
     6061 ccatacccgg tagttttcat taccgcctgc aaaattgaac cattcgtcaa gagggagcat
     6121 cccttccagc cgccttttca cctctgcatc ctcaaaccag gtctgcagcc attcaatatc
     6181 ttcttttcga aaaagacgaa gttcttctat attgctcatt gctttctcct ttattgcgcg
     6241 tatttttcag cttgcaggcg ataaagctct gcgtactgtg cctgattttt catcaattct
     6301 tgatgggttc cggcctccgc cacccttcct ttttctaaaa agatgatgtg gtcggcaaaa
     6361 cgggccgtgc ttaaccggtg cgagacaata atgactgttt tgccctgcgt cagcttttgc
     6421 agcttatcaa atatctcttc ctcaataaat acatccagcg cagaagaggg ttcatcaaat
     6481 attaaaatgt cggcacactc atcacgcata aatgcgcggg atatggcgat ccgctgccat
     6541 tctccccccg acaaattcct gccgccgaac aatctgccaa gctctgtttc atagccgtct
     6601 tcaagcttat gcaaaaactg atccactccg ccgaaagccg aagcactttt tattttggcc
     6661 aagtcggtgc atgaagaaat gtcgcccaga ccgatattgt atttcaatgt catttcgtac
     6721 cgcaaaaaat cctgaaacac ggccgcggca tttgaccggt aatgctctat atcatactta
     6781 taaagcggta aaccattata cgagatcgtg ccttgattgg gatcaaaata acgcagaagc
     6841 aatttaacga gtgtgctttt gcctgatccg ttttctccca cgagaacggt cgtcttattc
     6901 aatggaatat caagctgttg aatatcaagt accgttttgg ttccatcata agaaaattcc
     6961 acttgatcac atgtaaatcc tttttgcttt tgaacagctg gagcggtttc cccattttcc
     7021 atggaatttt tgctgtttaa aaaagaatgc acatttccga ggtgcctcgt ttctcttgct
     7081 ccgatcgcaa aagcagcgaa catttcattg attccttcat tgaactgaac cgcggctccg
     7141 ataaacagca tcacatcccc gatggataat cccccatgaa aagcctggtg aacgatgtaa
     7201 atcaggacgg cacctgcggc caaagattgt aataccgacc agaacagctg atacagcgcc
     7261 agtttttttt gatcgttgga cagcgtatgg aggagctcca tcgaggtgtt tttataaaag
     7321 gatttaaaaa aaggaacaag attgtatatc ttgacctctc cggctgtttc agacataaga
     7381 gggacacctg cataatattc cgcgcgccgc ctcagttcct gaacctcttt ccgtccttca
     7441 aaggtcgcgt tgtttaactt cgcctcccag tacagtttgg gaacggccaa tatgagaaac
     7501 agcagcggca cccacggtgc agccatgcca atcaataaac tgctggctgc aatcatcacc
     7561 attccgccga aggtttgaga cacgatggaa acccacatcg tgacaaaata ttcattatag
     7621 cggatgattt gtgtattggt atgaaaagat gcgtcttcaa aagccgcgat atcaggaatg
     7681 gaaattgcct ttttcatgag catttcatca agataagctt cgagcttggc ggtaaggagc
     7741 cttttctgca tttcagctac aggctgaagg gcatctacga tcagcgtaaa agcaatgtat
     7801 gcaaaggccg cccaaaccag tgcattccaa gaagacagct caaacggcgc ccgtgcaatc
     7861 tcatcgatca cctctgcact cagccagact aggagaggtc cgagcattgc attcagcagt
     7921 gtaattaaaa acagaaccgc cgacttaaaa ggatcgcagc gccaaaacaa cgttaaaccg
     7981 taaaatatga tggaagcggt ttgaggcagc tttttgaaaa acgaataaaa tttcagcaat
     8041 atacctcatc cttcccctga aacgatttgg cctgcatgcg gaacattctg ctgtattccc
     8101 cgttcttgtc cataagttcc tgatggcttc cctcttctgc gattcttccg tttttcaaaa
     8161 ccagtatgcg gtcagccatc tttaccgtac tgaaccgatg ggaaatcatg atcaccgttt
     8221 ttccctctgt gaagctttga aactgccgga aaatatcata ttcagcccga atatccaaag
     8281 atgcggccgg ctcgtccaat atgacaagtc cggcatcttt cataaacgat ctggctaaag
     8341 cgatccgctg ccattggcct ccagaaaaat cggtgccgcc ccattcaggg ccgattattg
     8401 tttccagccc ttcaggcaac tcttcgacaa tcggttccag cttggcggcc cgagcggcgg
     8461 cgcgaagttt ttcttcatcg cctaaagctt ccgttcggcc tatcgcgata ttgtgccgga
     8521 gtgacaattc gtatctgcca aactcctgaa acacgaccgc cattttgttt ctcagctgtt
     8581 gaagatcgac attgcggatg tctttgccgt tcactttaat ctcaccctca tcatactcat
     8641 aaaaacggca gagcagtttg atgagcgttg ttttcccaga tccattcgcc cctacaatgg
     8701 caattctttc tcccggtgat actgaaaagc taattcgatt cagaacatcg cctgtgtgca
     8761 tgtcatacga ttcaggctgt tcgtcttgtc cccgcatctc ttcatcttca agctcatcga
     8821 gcatatccaa gtcttcctca tccacatcag cttcatttac ccgggagccg gcagccgctt
     8881 ctctgaaagg atagcggaag gtgacatttt tgaattcgac tgccagcggt ccttcgccct
     8941 cgagagattc gccattggaa ggaagcctga tatccttttc ggcgttcata aaaagaaaaa
     9001 agtctcttcc cattctccat atatccaacg tatctgcacc ttctttggcg atatcccgga
     9061 gtgccgttga taattggaac acggccccca agtacagcga tatatccccc acagaaaaac
     9121 tgcttgaatg ggattgggac agaatccaaa agtaccccaa acccgttccc gcccccgata
     9181 agaaacccgt taaaaccgac cagcgcgcgc ttctgacctg aatattccgc agcacagaat
     9241 ataggccttt aaaagcagat tgatataaat caagaaagaa agaccccagg ccaaaaaggc
     9301 gtacttcttt ggccgatcgt ctcccgagca gaatgtggcg cgcatatgcg gccctccttc
     9361 ttacaggggc ataatccttg tgatattccc actccatttc attgtaatga ttatggacaa
     9421 aagcaaatgg agcggtcgac aaaataagga tgaaagcaag gacgggcgac agataggcga
     9481 tgatcaaaac gacgcccgcc aaagacataa cggcggtcac caagttcgaa ctgatattaa
     9541 tgaattggga aggaagccat gtcgaacgat cccgcagtgt ttccagccgg tccctgtact
     9601 ttggatcctc aaaaaaacgc atccccggaa tgcggtcaaa agcgtcgatc aacaaactgt
     9661 tgactgtgat catcgacctc tcagaaagca ttgccttcac ccatttttcc aatgatttaa
     9721 cgacactgac catgaccagg cttcccgcat aaatgacagc ccatatttct gcatagatga
     9781 cggcttcctg atcgacaatg ccgtcgatca tttgctttga aacgtacaat tggattaaag
     9841 gtgctccggc ttcgatcagc atgaagataa ccatgcaaat catcagccgc ggaccggatt
     9901 tccagaccat tttcccaagc aggcccgccg tttgcagcgg ctcttgaata tgcttcatct
     9961 tccacacatg cttcaccttc attttctata cctattgtgg tcattgatac gagtatattt
    10021 tggctttctc cggcgtattg acggtttcga tatcagccat gacccttggc tttaccggac
    10081 ggctccggtc gagaaggtgc tccttcccct tggatgcttc tcttagccat atttccaagt
    10141 caataacaga tctcatgtac tgatagccca tgcccagatc attatttgga tcttcagagc
    10201 ggatagccat agccagcaag tgtttccacc atatatcgcg cttaatgatg ccgagttctt
    10261 caacgaagac gcgctctccc ggctcaaata actgaagaac gtgtctgcgg tcattcataa
    10321 agcttttcct ggccatatgg gcatatgttg ttttcgttga tctgttataa acataggcag
    10381 gcaggatatc ggtgaaagat ttgcgaagaa gcattttaga gcctgcataa tgttcttcaa
    10441 gcccttttaa aacatcaaaa tgctgttcag gcggtacaga aaatgagaac tcgatcagcc
    10501 gccggtccaa aaatggatgg tacgtatgca atgtcacacc aacagcatcc atgtacctcg
    10561 ctctcggcca caaaaagtca tagtgaaacc tcttgcccca cactgagagc tcccggcttt
    10621 ttcgatagcg tagatgatcc tctttattga tctcccattc tctctttcgg tgttcttcag
    10681 tgaaatattc aggcagctca tattccgtat ctgaccacag caggtcgtaa tagagctttt
    10741 ctccaatata aggcatgaaa ggggcgattc cgtattgaaa tccgagcttc agcatctctt
    10801 tcatgctgcc gcctgaccat tcgcgaagca atttgtagat ttcagaaaac cgtctctgcc
    10861 gaagcaagga atcgatcact gacacttctc cgctaaaaat gaaatccccg ccctcacctg
    10921 taaggacaga cgaggcacca tactcctcag cgatcactgt aaaagtctca ttaaccagtg
    10981 aattggctct cggatcagga ccgtctacaa accaaagcgg atcacgccca atttccgcgt
    11041 ttggaatttt ggctgtagcg tctccaagaa tgatcaggcc ggggatatcc atatctcgca
    11101 tcatattctt tacaaggtcc ctgtcgtggc ttaatatcat gtcgggttcg gcaaatgata
    11161 tattgacggc cagcagctgt tccttgcgtc cgcctgcaac tgcggcggcg gttacggcag
    11221 ctgaatccag tccgccgctt aattcgacaa tatgcctttc atcctttaaa cgatctgctg
    11281 tcacttcctg aaaaagctcc cggaacctcg gaacagcgtc tccagcaaga tctttctcgt
    11341 ttaatagctg cggaagcccc caatagctgt gcacgtgaac cgcttgatcc cggccgagaa
    11401 aagcgtagga cgccgcaggc actttgcgta ttcctttaaa aaatgtccga tcttcaaagc
    11461 cgttttctcc tacagcaaag cccgaagtag gaaacattct gcacacatct tgatcgatcg
    11521 caaaaggaat gtcatgaaca agcaaaagga tgcgcatgtc attcgctgca taccattctc
    11581 ctttcggact gacccagtag taaaccggac gggttgcgta tgtatcagtc gccaaaacaa
    11641 ggctatgcag actgtcatcc caccagacca tcgtatattc gccatgcgag tgagacagca
    11701 tggcagcttt gtcctgcttc aatgatgcgt acagcttgtc atattgctcg atctttcggg
    11761 tgccatccga ttttgcgtta agaccgccgc tgatccagcc gtctaagatg acggggtgca
    11821 aaagatttat ttgagttgaa ggtctaaaag cttcatcgta tcggatatgc gcttcagcca
    11881 tgtttgcgat cccgcagctg tagctgtgaa tccgttccgc ccgtccccat ttcttgacgg
    11941 cggaaaccca ctcttgccat aaagcggtgt tgtttccctg cattccaaac catattttca
    12001 tactagagat aacacccacc tttcagcgta agcgctcatc ttatatgtct gtaaaacttt
    12061 taaattctta tttttatgat tcggatcgat cgatttgccg ttttccattt gaacccacgc
    12121 gtgagaaaac agcttgtcat caattttctt gaccccgatc atgagatcag catcagaccc
    12181 attgctgaat aatatagatt gaatcgttaa tgcaatagaa acgcatgaag tgaccaaatg
    12241 gtcgtcttca tcaagggaat acaaatattc gccgttccgg tgcagttcgt ctatatcaag
    12301 aagccctgca cctctttgct ttgcgctcgc atacagcgga aacaggtgga tcgcaatttt
    12361 ttcataagct tcttcaaagt cataatttaa cagcatcata cgtacaaaag catgaacggt
    12421 tgtaaaatat tcgtggtttt tgacaagcgc tctttttttc atcagctttt atcctctatt
    12481 ttaatgagct tatgatgtgt cagttcctgt atcgcctcat ttaatatcgc tgatagttct
    12541 tcttccgtct gatcgaacgc cgattgccac ttgatcagaa tatctttttt atcctttcgc
    12601 tcattttcaa tttcgatcca cagctctttt aaagcccctt ccaatccgaa atactgccca
    12661 ttgtccaggt ttaggacgat gcattcattt tccaacacgg ttgtcgctgt ctcttgattt
    12721 cgaataattt tcaaagatta gacctccccg gtatgcatga tttcagaaaa ataaaggaga
    12781 agagagccgg caagctctct ttcagcactt tatgcatgat gttctttcca cgccctcgtt
    12841 atcatttcag cgctggagcg ttttaaaaag agcctgcaat gcgacgatgc cctgaattta
    12901 ccaactgatc acatgaatca gattatcaca ggacaatatt aaaaaaaccg caaaaaacta
    12961 ccgaaaaccg acatgattag ccaatggcat caatgggcca ttattacggg atttattcgg
    13021 aggaaaaaga aaaagagagc ctatcgactc tcttttgcag ggaaaaacga atatatactt
    13081 tgtctatact ttctgcttga tcaaattaag catcgtccct ttttttactg cgcagtaccg
    13141 cgacgttact ttgagctttt tatagatttt gctcaagtga tactctacgt tccgtgtcga
    13201 catttgcagg tctgctgcga tctctttatt tgttttaccg ctggccacct tctgcaaaat
    13261 atccagttct gtgtctgtta aatgctcgtc caccgagaga tcggagtcga gcctcagttt
    13321 ttgcagcaag ccgtcgggaa ataacacagc cccttttaaa cacaataaaa tactcgaagc
    13381 tatcatgctg tctgtatacg atttatctat aaacccttta actccggcct cgatcaactt
    13441 attaaaatat gagtgaattt catctcccga aaacataatg ataattttgg attgaggttc
    13501 gatttccagc gttttaagag acagttccaa cccgttcatc cccggcattt ttaaatcata
    13561 aagaaaaacg tctatatgta cctcttggtt ttttaagagg tcgagagctt catttccttc
    13621 gtggcaaacg atgacatcca tattatattt ttttaatatt tccttcattc cggatgtcag
    13681 aaccctgtag tcgtctacta acaacacgcg tatcatcagt aacactctcc ttaaatcagt
    13741 ttcctccgaa caaataccgc aataaaaacc ccatgaatag aattgaagga tgatgtcggg
    13801 ttttagtgcc tttttgtggt ttttaccact atattctatg atagcatgat tatgtaatca
    13861 actggaagta ataaggaggt gacacagatg cgcaaattgg aaagtgctca agttaaaagc
    13921 tatggttcat tcctgactgt tactctttct aaaaagagca agccgggcga cggcaaattc
    13981 ggccgcggcg taaaacgcgg ttaagagtgt atgagaaaga gagagcctcg ggctctctct
    14041 ttttccgttc agcaatcaaa aaagagtgcg gatagttgaa atccgcactc ttttgccaat
    14101 caattaatgt ccgctgtgct cagaatgttt tgcacctgga gaaccgccct cagggttgtc
    14161 tccgtgatag ttgtgagcag cgaagatcca gacggaaccg gcaataatcg caaccgcaat
    14221 aaacgcggca aacagcgtat tcccgacttg gattttgccg ctgtcactct cagtcatatg
    14281 cataaacatt aagagctgaa gtccagcttg aatgatcgca aaaccgaaaa taatccacag
    14341 ctttgcagcc atgcttaaat ccgtatagat cacccacaag gccaataagg tcagcacaat
    14401 ggacaacacg aacccgacaa tatgcttcca aggaaagtgg ctgtgttcag ccgattgttt
    14461 tgctgccatt atacattcac caaccctatc aaatagacac cggtaaagat gaagatccat
    14521 accacgtcta agaagtgcca atacaaactt gagataaaca gcttagcaga cgtttgcggg
    14581 gtgaggccgc gctttttcgt ctgaagcaat atgccgataa tccagaagat accaatcgat
    14641 acgtgcagtc cgtgggttcc caatagaaca aagaatgctg accagtaagc acttgtcgat
    14701 aaagtggcac cttcgtgtac ataatgattg aactcataaa gctcatagct gacaaagcca
    14761 gcaccgagca acagggtaat gatcatccag atcatcacgc ctttcaaact gccgcggcgc
    14821 atttcatgca ctgcaatgcc gcatgtgaaa ctgctcgtta acagcaggaa cgtcatgatt
    14881 aaaacgagct tcgcgtcgaa cagttctgcc ggcagtacgc ctcccgctgt tctgttatga
    14941 agaacagcat aggtcgcaaa taacgtagag aataaagcaa tctccgctcc aagaaaaatc
    15001 caaaagccaa ggatattcaa ccttccgatt tcagaacggt attccatagg agcgttagaa
    15061 ttgctgtgtt ctgcatgttc catcaatccc gcctccttta cttggcattc tttcgttcag
    15121 tctcttttat ttcctcaaca cttacatagt agccgtcgtc atattcaaat gaacgaagaa
    15181 tcatacagag gaatacaccg atcagaccga cgattcccat ccagaaccat tcaaagacaa
    15241 gcccgaatcc agcaaatccg aagcataatg acatgataaa cggacggcct gaattgctcg
    15301 gcatatgaat ctttttaaac ttgctttcag gatgaatctc gacattgtct tccttcattt
    15361 gcgcaaatgc gtcaggtgaa gtgacctcag gcagaaccgc aaagttatag tgcggcggga
    15421 tcgcagaaga tgtagcccat tcaagcgtgc gacccattcc ccaagcatct cctgattcct
    15481 cgcgttttga atgacggaag ctgtagaaaa tgttatagca gagaacgatg aatcctgcgg
    15541 ccatcagcaa tgcgccgaat gtcgcaatca tgttcaatgc agtccagccg tcttctgctc
    15601 cgtatgtgta aatacggcga ggcattccct gcaatccaag gaaatacatc gggaagaaac
    15661 agatgttaaa gcccgtcatg aacagccaga agaaccattt tccgatgcgt tcgttcagtt
    15721 tgtgaccgaa cattttcgga taccagaaga tcaatccggc gaaacatgca aacacagtac
    15781 ccgcgatcag cacgtagtgg aagtgcgata cgaggaagta tgtgttgtga tattgataat
    15841 ccgcagctgc catcgcaagc ataacgcccg taacaccgcc gatgacgaag ttcggaataa
    15901 atgcaagcga ccacagcatc ggcgttgtga ttttaattct gcctcgatgc agcgtcaaca
    15961 gccagttaaa gattttaacc ccggtcggca ccgatatcgc cattgtcgta atcgagaaga
    16021 acgagttgac cgccgcgctg ttgcccattg tgaaaaagtg gtgcagccaa acgataaagc
    16081 tgagaaccga aatcgccaca atggaataaa ccatcgcttt atagccgaac agctgctttc
    16141 tcgcaaatgt tgcaatgatt tctgaaaaaa taccgaaagc aggcaaaata acgatgtaaa
    16201 cctcaggatg tccccaaatc cagaacaggt tcgcccatag catcggcata ccgccgtttg
    16261 ccaaagtgaa aaaggctgtt ccgaacaagc ggtcaaatgt catcagcgcc aaagccactg
    16321 tcaagacagg gaaggcgaaa atgataatca cacaagtgat cagcgttgtc caagtgaaca
    16381 tcggcatccg ccatagagtc atgccttttg tacgcatttt caggatggta accataaagt
    16441 tgatcccggt gagaagcgta ccgatacccg cgatctgaag tccgagcaag taatagttct
    16501 gtccaggtcc aggactcagc tcattgcctg caagcggcat gtaagccgtc catcctgcat
    16561 tcggcgatcc gccgatgacg aatgaaatgt taaacagcat cgctccgacc atgaaggtcc
    16621 agaagctcaa gttgttcaag taaggataag caacgtcccg cgcaccgatt tgaagcggta
    16681 cgaccacgtt cattaaccca ataagaaacg gcatcgccat gaagatgatc atgatcgtac
    16741 cgtgagtcgt aaatacttca ttatagtggt tggaatctaa aaagccgtta ttaggaagcg
    16801 tgagctgggc acgcatcatt aacccgtcga caccgccgcg gaagaacata atgactgcgg
    16861 caatgatgta catgattcct aaacgtttat gatcgacggt ggtaatccac tctctccaaa
    16921 gccatttcca ttttttgaag tatgtcagca caaatacgat tgcaattgaa gtaagcaaaa
    16981 tggaaatctg tgctccaaga attaatgggt cacctgtaat tatgaattcg tcccatttca
    17041 aattcatgca agcttcctcc tttcctagtg agaatcttgg tcttcagatt gtttttgatc
    17101 tttgtttgtc tttacgtttt caaacggatc tgatttagag tgcggagaca acggtttata
    17161 gcccagtctt tcgcgcgctt taatggcgta ttccgcatca tttccgtgat taacgtactt
    17221 caggtgtgta gatgagaacg tcatttcgtc cgcatgctga ggaagcatca gttcatcgta
    17281 ctgggttttc gtcagcttgg gagcttcttt ctgcgttttc ttcacccagt cattaaactt
    17341 gctttcagat accgcattga cattaaactt ttgttctgca aaaccttcgc ctgtgaagtt
    17401 tgcatttcgg cctttataag taccctcatg gtctgcctgt aaatattgct ccatttccat
    17461 tccggacatg gcgtattttt gcccgccaag ctgcggaatc cacagagatg ccatagagtc
    17521 ggcagatgag attttaaaca agatcggtct gtctgtcggg atattcaaat agttgaccgt
    17581 ttcgatatcc tgttccggat agctgaatac ccatttccaa tcgacagatg tagcatatac
    17641 gaccaaaggt tccttgtcct ttgatgcttt tggagcctct tctagagaat aaattgtttg
    17701 aactgtcggc actgacagcg caataacaat taaaatcgga accactgtcc agacgatttc
    17761 taaaaatgta ttgccttcta cttccgggct gtaaggagac tttctgtctt tacgctcacg
    17821 gtatttcaca atcatcacag taaaaaggac aaatacgacc gctacgataa acagcataaa
    17881 tccaatcgat aatagaataa gatctctttg ctgcgaagca accggtcctt taggatccaa
    17941 taccgcgatt tgactgcagc cgcccaataa aaaaacggag gaaagcagag tcagcataat
    18001 cagtggttta aatgctctga acaagaggat caccatcctt ccttaatgat gtctaaaatt
    18061 tggtcagaat atctaagata aaaggattct gaaaaacttt tttcttctac cttgctatgc
    18121 tatcaaaatc ttcaccaatt agccttattt ttttcgattg ttcacctttt tttcacccaa
    18181 atgtcacaaa atcgtcaaaa tttgttcatg atattatgaa taacaaagga aaaagactgg
    18241 taatttttta gttcttttta cacacatagc aagcgctgac aaatccctcc ggaacaaaaa
    18301 atctgtcaaa tttaggttta ccacaataaa aaactttggt caatcattaa tttcacattg
    18361 ttaaattttt tcatggtgaa tcattatcct tctcccttcc ttttccctgc tgacaaccgg
    18421 ttttaaacta aagaacatca aaaaagagct ttcttctgtg actgaaagct cttttttatc
    18481 ctatataata ggcgttatcg cattctagct ttgatagccg ttcggatgtg ctttaaacca
    18541 cttccacgcg ctgtcaatga tcgtttccag ttcggcgtac ttcggctgcc atccaagctc
    18601 tttcaccgct ttttccgaag aggcgatcag ctgtgccggg tctcctgcgc ggcgctctgc
    18661 aacctccgcc ggtatcggac agcctgtcac tttccgggca gtttcaacga cttctttgac
    18721 tgagaagccc gttccgtttc cgagattgta tacggcgctt tctccgccgt ttcgaagcct
    18781 ctcgacagcg agaatatgcg cgtcgaccag atccatcaca tggatgtagt ctctgatgca
    18841 cgtgccatcc ggagtcggat agtcgtcgcc gaaaatcata atcttgtccc gtttgcctag
    18901 cgcgacttga agaatgatcg gaatcaggtg cgtttcaggc tggtggtcct cgccgatcaa
    18961 gccgtctaca tgcgccccgg caacattaaa gtagcgaagg acgacatgac ggattccgta
    19021 tgccttttca gaccacttca gcattttttc aatggcaagc ttcgtttccc cgtacgggtt
    19081 tgtcggatcc gtcggatctg tttccataat cggcacccga tccggttctc cgtatgttgc
    19141 agcggttgat gagaaaacaa tttgcttcac atcgaactct ttcatgacct ttaacaggca
    19201 aacagctccg taaacgttgt tgtcataata tttgagagga tctgttacgc tttctccaac
    19261 caatgaatcg gccgcgaaat gcatgacagc ctcaatgtcg ttttcctgaa acacctttct
    19321 tagaaatgct tcatcgcgca gatctccatt atagaaagaa gctcccttta aagccgcctc
    19381 ttcatgtcca gtttgcaggt tatcaataat tacgacatct tcattgcggc ttaacagttc
    19441 cgctacagca tggcttccaa tatagcccgc ccctccgcat actaatattg ccaattcatt
    19501 tctctccttt cagcggcgtt atccttctat tttaaaatct ataaaacgcc tgtgaatctc
    19561 tttttcaaac aaagatgata tatttgcttt tttcatttta ccaccttcag cattttccgg
    19621 cttgtatttt catcatttct tcaaataaaa agttggggga aaaacgaatt gagagacctt
    19681 cattccatta aataccttac aaggaatagt tcgggttttt atccatatca atggttttct
    19741 attggtgaat caacgcgatt ttgaggcaaa agctatactt ttttcactgc atttgaaacc
    19801 aatgttcttt ttttccactt aatgctgatc ggtaatagta ttttcgtatt acccttcttt
    19861 aacccataca gcaactaagc ccaaagaacc ctctccaccc attagatctt taatctaaat
    19921 aaccccttca aaccatcgat tttccaatat ttccacacaa tgacctctca aaaatccctt
    19981 ccttgttttt agaatattca aaggatattc ggctgcaatt gagaaattct taatagggaa
    20041 aaatgatcat ttttatttga atactatcca gtcagtaatt gattgtttat tattataagt
    20101 aagaatctaa gattttttgg tttttttagt cagttattta gggaataggt aggtttatca
    20161 atgatgactt tgtgaatttt ttatgaaatt tgtcattgtt ttcacatggc tgttgtttta
    20221 taacttttat tgcatctcaa ggaagaaccg ttttttcttt gaggtgaaca acgtcttatc
    20281 atattggagg aagctatgaa tactcaaacg aaacacaagt tggacaaaga ttgggtgatt
    20341 ttgatgaagg aggcgaaaaa acttgggctg caaattgaag atgtgaaaga atttcttcgc
    20401 agtcagccca tccaaagcga tgctgaaaaa cagataaagc aataagcgtt taaaagcatc
    20461 agttatccaa aaaaacaggc ggttctgttg aatcttggtc tatcaagatg atccaaccgg
    20521 ctgttttaac gagtgtttta attgataatg acgtatttga gcagcaggct tgctgcctgt
    20581 gtatagattc tgtctgctcc atagaaacga gcattttaag gagcagcctt accttttgcc
    20641 ctgtacatag gttgtttcac tttttccagc ttcactctct taaggggtac cagaccggat
    20701 tgattaaggc gttttagagg cattgctgac caacgctgat gccagcagcc ccatacactt
    20761 tcttctgtat cggtttcgat tgcctttctc ctgaaagggg gcggagcttt tggccttaat
    20821 ccttttgata ccatcctcgg gcttcctttc catactccct tttctgttaa ccatccgcct
    20881 atataatcgg ttttttcgat gttaaatatc taaaatatca attttactga tggttgttgt
    20941 tatcttaaac tgaattcatg acccattcca gaggaggatg atgaatatgg ggatagcagc
    21001 aatctgcgga agctcccgcg aaaacggaaa tacggaagag ttggtgaatc gattaggtag
    21061 acggacttga tgccgataag atctacctgc gaaactatca cattgagccc gtatcggact
    21121 acaggcacgg caatacagcc cctttgtatc ctgatgatga ctacagagac ctgatcagcc
    21181 gggtgctgga gaaggatatc ctgatttttg ccactccgat ctattagtac ggaatgtcgg
    21241 gtttgatgaa aaactttatt gaccgctggt cacagacatt gattgagcac gggagatctg
    21301 catttaaaca gcaaatggcg aaaaaaacgg tctacgtcgc ggctgtcgga gacgatgatc
    21361 cccgcttgaa agggctgccg cttattcaac agtttcaata tatctttgat tttatgaaca
    21421 tgacattcga cggctatttg ctcggcaaag ggaacaagcc cggcggcgtg gtgacagacc
    21481 ggacagcgat tgtgtctgca aatgaactga gaaggaagct ggcagaggcg gaaacggggc
    21541 ggaaagcatg gcaaataaaa aggcgaacaa acggttttat ttatggaaaa agcatttatt
    21601 cgagatgatc aggtctttca tcttatataa ataaaaggct ttgtgaaaat tgaagaataa
    21661 atccggagct tgttacatac ctttgttgta tcttttcaga caaacacaag gagggtcaaa
    21721 gaacaaatgg gagaaggcaa aatagattac agcaaagctg cggcatctcc ggagttccag
    21781 cggttgttaa agcggaaacg ggcttttatt gtaccgatga cgattttctt tttgctcttt
    21841 tatttcctgc tgccggttat gacatcatac ttcacatttt tgaatcagcc ggcagtcggg
    21901 gccatcacgt gggcatgggt tttcgcgatt gctcagtttg ttatgacgtg gacgctgtgc
    21961 attgtgtata cgaaaaaagc cggtcaattc gatcaaattg caagcgattt caaaaagaag
    22021 attggaggcg ttgattcatg agtgccacag cctttatttt gtttcttgcc attgtcgccc
    22081 tcacgcttgt cattacgtat ttcgccgcta aacagacaaa aacggccaat gagttttaca
    22141 cggcgggagg gggacttacc ggcattcaaa acggactggc tattgcggga gattacatgt
    22201 cagcggcttc tttcctcgga attgccggga tgatcgcttt gaacgggttt gacggtttct
    22261 tctacagcat cggcttcctc gtcgcttatt tagttgtcct ttatattgtg gcagaaccgc
    22321 tccgaaacct cggcaaattt acaatggcgg acatgattgc ctctcgtttt aaacaaaaga
    22381 aaattcgcgg tgtcgccgca ttaaacacaa tcacgatctc caccttttat atgattgcac
    22441 agttagtcgg cgccggcgcg ctgatcaagc ttctgctcgg catcgattat acgctggcag
    22501 tgtgcattgt cggggttttg atgaccatct acgtcgtatt cggaggaatg attgcaacca
    22561 gctgggtcca gatcatcaag gccgttcttt tgatggcggg gacgctcatc atttcggtca
    22621 tcgttttttc aaaattcggc ttcagcctga cgaacatgtt cgaacaaatg aaaacagcta
    22681 ctccgctcgg ggcggatttt ctaaaccccg gcaataagta taaagttcct cttg
//
