LOCUS       NZ_BBXG01000029        20828 bp    DNA     linear   CON 08-AUG-2024
DEFINITION  Herbidospora cretacea strain NBRC 15474, whole genome shotgun
            sequence.
ACCESSION   NZ_BBXG01000029
VERSION     NZ_BBXG01000029.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Herbidospora cretacea
  ORGANISM  Herbidospora cretacea
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Herbidospora.
REFERENCE   1
  AUTHORS   Komaki,H., Ichikawa,N., Oguchi,A., Hamada,M., Tamura,T. and
            Fujita,N.
  TITLE     Genome-based analysis of non-ribosomal peptide synthetase and type-I
            polyketide synthase gene clusters in all type strains of the genus
            Herbidospora
  JOURNAL   BMC Res Notes 8, 548 (2015)
   PUBMED   26452464
  REMARK    DOI:10.1186/s13104-015-1526-9 Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92859)
  AUTHORS   Hosoyama,A., Oguchi,A., Ichikawa,N., Kimura,A., Ohshita,R. and
            Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-MAY-2015) Contact:Director-General Department Of
            Biotechnology National Institute of Technology and Evaluation,
            Biological Resource Center (NBRC); 2-49-10 Nishihara, Shibuya-ku,
            Tokyo 151-0066, Japan URL :http://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Noncontiguous Finished
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: newbler v. 2.6
            Genome Coverage                   :: 71x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001570605.1-RS_2024_08_08
            Annotation Date                   :: 08/08/2024 02:39:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,566
            CDSs (total)                      :: 7,487
            Genes (coding)                    :: 7,430
            CDSs (with protein)               :: 7,430
            Genes (RNA)                       :: 79
            rRNAs                             :: 4, 5 (5S, 16S)
            partial rRNAs                     :: 4, 5 (5S, 16S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 10 of 57
            Pseudo Genes (incomplete)         :: 49 of 57
            Pseudo Genes (internal stop)      :: 3 of 57
            Pseudo Genes (multiple problems)  :: 4 of 57
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:10:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 20828
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBXG01000029.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20828
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..20828
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20828
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[7400:10828](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(7401..10828)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            complement(<1..1224)
                     /locus_tag="AW270_RS41965"
     CDS             complement(<1..1224)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012762.4"
                     /locus_tag="AW270_RS41965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cellulose binding domain-containing protein"
                     /protein_id="WP_174549918.1"
                     /transl_table=11
                     /translation="MGPRLSSWRRALMVAAAMLLAVTGLAVMQAPAGAAVACQVTYAKQ
                     WDNGSGFGANITINNLGDAVNPWRLTYTWPGSQTVQQGWNGTWTQSGQNVTVVAPSWAG
                     SLGTGQSVQIGFNGQVSGTNTNPTSFSLNGTVCNGGPSPSPSPSPSQQALVVSPTSVSV
                     PEGGTATYSVRLQSQPSSNVTVTTTAGSGDTNLTATSGTSLTFTSSNWNTPQNVTLAAA
                     QDSDTTNGSRTFTVASSGLTSVNVTATEADDDVTQTQALVVSSTAVTVPEGGTATYTVR
                     LQAAPSGNVTVTNTAGSGDTNITVSSGASLTFTTSNWQTPQTVTLAAAQDSDQTNGTRP
                     ITVASSGLTSVTVTATEGDDDIVNPGRVDNPYAGATGYVNPDWSASAASEPGGSAVANT
                     STAIWLDRI"
     misc_feature    complement(1253..1267)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.15"
                     /tool="antismash"
     misc_feature    1254..1268
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.15"
                     /tool="antismash"
     misc_feature    1265..1278
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.16"
                     /tool="antismash"
     misc_feature    complement(1300..1311)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.92"
                     /tool="antismash"
     gene            complement(1332..1931)
                     /locus_tag="AW270_RS35435"
     CDS             complement(1332..1931)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653115.1"
                     /locus_tag="AW270_RS35435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_061300519.1"
                     /transl_table=11
                     /translation="MESLLQGATRLFAALGYDATTLKQIADSTGIDPAEEGFGGSKRDL
                     YLAVIERAARIETEELEGVINEMMTADQISVADAVHEIVDRYIDFCVAHPEFPALWIHR
                     WLYDAADLTGLERQYSQPLITMTTSVLEQAADAGYIDDTADMEYCVWTLIWCVHGFVQG
                     GVLDEAGDRMGPENPEVLARFRQHLHRLAARTLNLS"
     misc_feature    2076..2086
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    2145..2160
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.03"
                     /tool="antismash"
     gene            2285..2872
                     /locus_tag="AW270_RS37145"
     CDS             2285..2872
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634649.1"
                     /locus_tag="AW270_RS37145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_245675017.1"
                     /transl_table=11
                     /translation="MTTVLATAGIAVAGLGATGAASTLAAPPHANPVRIHTKPAAIVKP
                     LEKPLVKEPSFVKPAVFTGTTTASYFWDDASGRAGDTGLPASGKPMQKGMAASPSWPLG
                     TEGYVVYKGQKKPFFVGDRGPGVPSSKGVMLDLDGQTFAELTGGSFDMTTLAVKGNGGA
                     GHIPIEYHITKWGDGTGLKAAPVPFSLGAWRH"
     tRNA            2925..3001
                     /anticodon=(pos:2959..2961,aa:Lys,seq:ctt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="AW270_RS35445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Lys"
     gene            2925..3001
                     /locus_tag="AW270_RS35445"
     gene            3105..4013
                     /locus_tag="AW270_RS35450"
     CDS             3105..4013
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024783.4"
                     /locus_tag="AW270_RS35450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HNH endonuclease"
                     /protein_id="WP_061300596.1"
                     /transl_table=11
                     /translation="MSLGDDLDSRVRGAAMAWLRRRSTPENPVVSRAELLGFQFEGRTF
                     PLVDNQLGIRKPQGFSAALSILTTYRSDGRSAPYEDAVGDDGLLRYKFQGNPSHYTNEG
                     LRQAHLQGVPLMWFVGVQAGLYLPFFPVWITAVEEAAKQVAVALEEAQRMMPVEGPVSP
                     LERRYAERVTQQRLHQPVFRQRVIQAYETSCAMCRLRHRSLLDAAHILPDRHSLGIAAV
                     SNGLALCKIHHAAFDQNILGIRPDFVIEVRSDILEEIDGPMLKHGLQDMHDQPISLPRH
                     RADRPHRNLIEERYEMFRSAG"
     misc_feature    3366..3368
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3962..4210)
                     /locus_tag="AW270_RS35455"
     CDS             complement(3962..4210)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW270_RS35455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_061300521.1"
                     /transl_table=11
                     /translation="MIWPKLFRRLAPYFAAGFPDLDQFDSWLGDDGDTITLVDPEDAVV
                     ETVTYKAGKVRNGRTIAFGRGQPALRNISYRSSIRFR"
     misc_feature    4197..4210
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.96"
                     /tool="antismash"
     misc_feature    4307..4321
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 21.8"
                     /tool="antismash"
     misc_feature    4347..4359
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.37"
                     /tool="antismash"
     misc_feature    4413..4426
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.03"
                     /tool="antismash"
     gene            complement(4459..5070)
                     /locus_tag="AW270_RS35460"
     CDS             complement(4459..5070)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012886893.1"
                     /locus_tag="AW270_RS35460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA-binding response regulator"
                     /protein_id="WP_061300522.1"
                     /transl_table=11
                     /translation="MLTLRILLAEDVRIVRGALAALLEIEPDLTVVAQVGSGADIVPAA
                     LEHRPDVAVIDVDLPVIDGLSAAEELHAKLPSCRTLILTGLGRPGTLRRALSVSVSGFL
                     LKDTPSERLAQAVREVAAGRRIIDPQLALTAWDVGEIPLSGREIQVLRLAAGGAEPPEI
                     AAQMHVSVGTVRNYLTKIVTKLNARNRVDAIRIATEAGWI"
     misc_feature    complement(5059..5061)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(5161..7341)
                     /locus_tag="AW270_RS35465"
     CDS             complement(5161..7341)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.4"
                     /locus_tag="AW270_RS35465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sensor histidine kinase"
                     /protein_id="WP_061300523.1"
                     /transl_table=11
                     /translation="MARAVIAAVLSAYTFNALIFVWDEGLRGWPLGAFVVCLLTAFGLQ
                     LVHSTRDVLLWSSRPKALTLSAQAVVTFAPFLWAGPQAGSSAGFLAGSMLLAVAGPLRW
                     ALYAAVPATVLIALTWKGMAPLDVVYGTYFTALTGLMVYGLSSLASLALTVHAARGELA
                     ALAVAQERLRVARDVHDLLGYNVSALTLKSELAYRLLPGSAERARRELRDVLTLSSQAL
                     GDVRVVAGGSRPMSLAAEVRSAESMLIAADMAVEISLSPCPLPEEVDTVLAIVLREAIT
                     NVLRHSKARHCRVETDLAGEHIVLRVVNDGADAPAPVPDAGVGLDNLSARVEAAGGTST
                     TVLDGDRFTFTAEVPLAPPAPPPVDDPVTRTVAQITGQPWHLRVARTIAIVVLLGYGLL
                     MVVNVLAQSVDSLGLLEFALCVAVLVGVQIALILGFLRGAALPVQVVATYLPLLWIGAP
                     WGSMGGFLAGTTLIVLSGAWRWSCYAAVGVSVAALSVFHGDPGEWTAYLTLSTLLTGLV
                     VYGISSLCGLVAQVDQARDELARGAVTRERLRVARELQDLLGQDLAAMTVKSERAYRLL
                     PGSADRARAELAEVLDVARRAVGEVRSVASGYRHMSFAAELDTARATLAAAGVRVHASA
                     GEVPEEVDAVLAVVLREAVTNVLRHSAATCCEIVVTADVTLTVRNDGVPALPPPGEPGT
                     ALDDLAERLNSIGGSLKCVRDSGTFLLKVDIP"
     misc_feature    complement(5179..5181)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7401..8849)
                     /locus_tag="AW270_RS35470"
     CDS             complement(7401..8849)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013077.4"
                     /locus_tag="AW270_RS35470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_061300524.1"
                     /sec_met_domain="PF00881 (E-value: 1.8e-14, bitscore: 46.6,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDTLPPFPLWSFREDVFVEPDPDEGVVVVHSRWEDTVFPMPAPP
                     VVEALRRMSLGPISLGNVIRSSADRQALKALLDRLAHLVVRSFGVDREQPLVSVVPLTP
                     QAGFHLPEGPLVHPVRLSRFAVLTTDGTNYLLESPLSQHRVILHRADAIGHLGTLMRPT
                     VPASVGHETRSVIAFLMAAGMVVQAATGDPFQRIEFDEDNDPALTTWTPIDLMFHTRST
                     LGRHDQDFGVTYPLGEHGSVEPVVKETGPGIPLPRPSWPDLAGDPPFSAVVEAHRPAQT
                     FAARPITVEDLGTLLYRTARVRSLRGSPSTEATTTTSDRPSPTSGDCHELELYAVVDRC
                     AGLERGVYHYDPYGHRLTPLDGDPDELLVSANLASRPPVLLMITARFRRLSWKYNGLGY
                     SLVLTDAGALVQTLSLAGTAMGLSGSRIDGPDIDAAAHVFGLDWRTESSVCGYAVGHAG
                     SGFAEDEYPVNDADWPMLAAALLA"
     gene            complement(8873..10828)
                     /locus_tag="AW270_RS35475"
     CDS             complement(8873..10828)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cyanobactin_D_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Goadsporin_CD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NHLP_CD_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014661.4"
                     /locus_tag="AW270_RS35475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_061300525.1"
                     /sec_met_domain="Cyanobactin_D_RRE (E-value: 5.1e-10,
                     bitscore: 31.8, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="Goadsporin_CD_RRE (E-value: 1.1e-21,
                     bitscore: 69.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="NHLP_CD_RRE (E-value: 3.9e-13, bitscore:
                     41.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 3.6e-74, bitscore: 242.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGFKRHWRAVTVPGDGVYLTSARATVALRGDHIETVAPLLDGS
                     HDLADLHEQTGLGAADLGRLLGRLSEADLVAPQPDVDVAPEVRAYWDLAGLGLPDGEVE
                     VVSLGDSALVERALKELGLRTGGDGPVVVVCDDYLDPALASVNAARLADGRPWLPVAVD
                     GPDLWIGPGFRPGESACWECLATRLRLRRQAPLTLAPPASLPQTRSVGAQIAATRIAGW
                     LAGRPLDTLWTFDPLTLEAAHHPVTRRPQCPECGTPDVRGGPVRITSRPKVQAHRSAGL
                     QETWDRYVHLTDPVTGVTDEIRRDPRAPAFLNAYLSGRNLALPVSGLRANSGGKGGTPL
                     EARVGALCEAVERYCGSRLGEEPVVHDSYRGLGAQAVHPDAVLLFDPRQRAPFDETRAT
                     EWTPLYTLDGEKRYLPTDLLYFSEGGQADSNGNAAGSSVEDALLQGFFELVERDAVGIW
                     WYNRTRQPEVVLDDPWTDRLRDDYATLGRDLWVLDLTTDLGIPAMAAVSTKDGHEVMLG
                     FGAHLDPETAARRALTELGQLLPAATDIDMRPWWGRVSTLSHPCLLPDGVAAPGSYTGD
                     NDLKADVDLIRKHDPLILDQTRPDIGVPVVKVVVPGLRHFWPRFAPGRLFDVPVKLGRL
                     DRPTAYDDLNPVALFM"
     aSDomain        complement(10541..10822)
                     /aSDomain="Goadsporin_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     goadsporin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AW270_RS35475_Goadsporin_CD_RRE.1"
                     /evalue="3.70E-22"
                     /identifier="RREFam013.1"
                     /label="AW270_RS35475"
                     /locus_tag="AW270_RS35475"
                     /protein_end="96"
                     /protein_start="2"
                     /score="69.3"
                     /tool="antismash"
                     /translation="VGFKRHWRAVTVPGDGVYLTSARATVALRGDHIETVAPLLDGSHD
                     LADLHEQTGLGAADLGRLLGRLSEADLVAPQPDVDVAPEVRAYWDLAGL"
     aSDomain        complement(10553..10822)
                     /aSDomain="NHLP_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     NHLP/Nif11 LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AW270_RS35475_NHLP_CD_RRE.1"
                     /evalue="1.30E-13"
                     /identifier="RREFam015.1"
                     /label="AW270_RS35475"
                     /locus_tag="AW270_RS35475"
                     /protein_end="92"
                     /protein_start="2"
                     /score="41.8"
                     /tool="antismash"
                     /translation="VGFKRHWRAVTVPGDGVYLTSARATVALRGDHIETVAPLLDGSHD
                     LADLHEQTGLGAADLGRLLGRLSEADLVAPQPDVDVAPEVRAYWD"
     aSDomain        complement(10661..10822)
                     /aSDomain="Cyanobactin_D_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing D protein in a cyanobactin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AW270_RS35475_Cyanobactin_D_RRE.1"
                     /evalue="1.60E-10"
                     /identifier="RREFam007.1"
                     /label="AW270_RS35475"
                     /locus_tag="AW270_RS35475"
                     /protein_end="56"
                     /protein_start="2"
                     /score="31.8"
                     /tool="antismash"
                     /translation="VGFKRHWRAVTVPGDGVYLTSARATVALRGDHIETVAPLLDGSHD
                     LADLHEQTG"
     misc_feature    complement(10813..10827)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 20.55"
                     /tool="antismash"
     gene            10900..>11952
                     /locus_tag="AW270_RS35480"
                     /pseudo=""
     CDS             10900..>11952
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1192: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017576595.1"
                     /locus_tag="AW270_RS35480"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="RNA-guided endonuclease InsQ/TnpB family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAQTVKRAYKYRFYPTSEQAEELSRTFGCVRLVYNKALEERTRAY
                     AEGRKIGYEQSLRHLQTAYANFFAGRARHPVAKSRKRSRRSAEYTRSAFTWLNGELKLA
                     KMRKPLAIVWSRPLPEGAQPSTVHVSQDTAGRWFVSILVEERIRSLDPAGTAVGVDVGI
                     TDLVTLSTGEKIANPRHAQAMRRKLTRAHRTLTRKKIGSRNRAKARLTLAKTYARMTDR
                     RRDFLHKLSTRLVRENQTVVIEDLSVRSMLRNRTLSRAISDASWRELRAMLEYKTHWYG
                     RELLVVSQWFPSSKMCSNCGALRETLPLKVRTWVCDCGVTHDRDVNAARNILAAGLAER
                     SNARGADVRPQ"
     gene            complement(12017..12253)
                     /locus_tag="AW270_RS35485"
     CDS             complement(12017..12253)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) triceptide_precursor"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW270_RS35485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_061300527.1"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATITHTEDWRFAELVMRAWTEPALAARYEDDPAGTLAQFGIDLD
                     AGDAPPLSAGGDPLRIADLTQPSLLSAKWTYCG"
     gene            12493..13359
                     /locus_tag="AW270_RS35490"
     CDS             12493..13359
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.4"
                     /locus_tag="AW270_RS35490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_061300528.1"
                     /transl_table=11
                     /translation="MYHDLQINRLRALVTVVELGGFRKAAEALHVTQPAVSQQIRQLGG
                     LVKGPIFTSTGRVLELSTEGEELLGYARRIVALNDEAVGRFVPPSGTARLTIGVVNQLA
                     EALPEILRLLNRGLPHVQVGVQTGLSESLENQVASGQLDLALLLQSEPVTAPAHQLGEM
                     RMDWFGRPAHGEGAALPLTLFTEPCTLRRRIVDALDESEVPWRVAYEGPELVGLRAAAK
                     AGLGVACLVANGDELWGLPRAARLALPTAPGPLPVTVALSANATNSEYVPIAERAFQQA
                     LRDYPFA"
     gene            complement(13400..14107)
                     /locus_tag="AW270_RS35495"
     CDS             complement(13400..14107)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW270_RS35495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="CAP domain-containing protein"
                     /protein_id="WP_061300529.1"
                     /transl_table=11
                     /translation="MRHLALLGAAALVAAAVTVPASPALAAAPLAGAATCADIDFVFQP
                     ASAFPDTARGRYDNHMQGSRIEKSVLCLVNAERTSRGLQPVKRYIALRGTTVALSSAAS
                     KEVAAAVRIRWWGTVAQVGNCTPDKYNPSRCDVHINPETGTDPADRAKAAGYCRRGSSW
                     AVGENAYQGWGRASVTPRAAVTWWMGSQRHRDTILTPGYTEMYAKAALGSADPSVSATP
                     AATYVQMFGRCTS"
     misc_feature    14155..14169
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 21.65"
                     /tool="antismash"
     misc_feature    14290..14304
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
     gene            14318..14806
                     /locus_tag="AW270_RS35500"
     CDS             14318..14806
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW270_RS35500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_061300530.1"
                     /transl_table=11
                     /translation="MSPFKKAALMAAVTTSALALAAPAHADEPGELTARLTITGSGSEC
                     RVLTVGKVGMTNAQAQYLVDNGATARVEVWADDPIYDNRVYKGPAAALSAVSDKNGGGL
                     FIVSDLRLSCVNYLDEDDKPPFDYGDEIYTKIVFQGPGYPRMTKKSNVIHRNFGFAEP"
     gene            complement(14984..16048)
                     /locus_tag="AW270_RS35505"
     CDS             complement(14984..16048)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893269.1"
                     /locus_tag="AW270_RS35505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_061300531.1"
                     /transl_table=11
                     /translation="MTPTEESPTGAASPAPLTLSQLAEMAGVSMATVSKVVNGQTDVGP
                     KTRAMVEGLIHEHGFRRQRRRIKPAGLIELVFHELAGDYPIEVIRGVQQVTREARQGLV
                     ISELGGRHVPGQGWLESVLSRRSAGVITVFSGPTEEQRARLAAREIPLVVLDPAGDPGR
                     AVPSVGATNWSGGLEATRHLLELGHRRIAMITGPDWALAGRARLDGYRAALDAAGVPVD
                     PDLICPGDFQIEDGLTHTHRLMDLPEPPTAIFASNDGQAVGVYHAAYARGLRIPDDLSV
                     IGFDDMPAWRWATPPLTTVRQPLTEMGVMAATMLISMAEGETLPQRRVELGTELMIRSS
                     TAAPARRRTPPISA"
     misc_feature    16146..16160
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.16"
                     /tool="antismash"
     misc_feature    complement(16171..16185)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.53"
                     /tool="antismash"
     gene            16425..17834
                     /locus_tag="AW270_RS35510"
     CDS             16425..17834
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013132383.1"
                     /locus_tag="AW270_RS35510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="endo-1,4-beta-xylanase"
                     /protein_id="WP_061300532.1"
                     /transl_table=11
                     /translation="MTPHAILTIARRTLVAGAALVLAVPLTASAAAATLGAAAAQTNRY
                     FGAAIAAGRMNDSTYMTILNREFNQVTAENEMKWDATEPSRGSFNYNNANRIVNHAISR
                     GMIIRGHALLWHQQMPGWAQGLSGSTLRSAMINHVTQVATYFRGKIHSWDVVNEAFADG
                     NGGGRRQSSLQATGNDWIEAAFRAARAADPGAKLCYNDYNTDGINAKSTGIYNMVRDFK
                     QRGVPIDCVGFQSHLTNSAPSDYQANLQRFADLGVDVQITELDISGSNQANAYATVTRA
                     CLAVARCNGITVWGIRDSDSWRTGANPLLFDSSGNKKAAYTSVLNALNAATPSPTPTPT
                     PTPTPTPTPTPTPTPTPTPTPNPGGPCRVAYSVNPWNTGYTAAIIVTNTGSSALNGWAL
                     AFTLPSGQTITGGWNAAYTGSSGQITARNLSYNNAIPAGGSVEFGFQATHTGNTAAPTS
                     FTLNGSTCTTA"
     gene            complement(18792..19832)
                     /locus_tag="AW270_RS35515"
     CDS             complement(18792..19832)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024799.4"
                     /locus_tag="AW270_RS35515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_218009430.1"
                     /transl_table=11
                     /translation="MSRRRVTLADLAQAAGVSRTTASLVMTGRGRELRISHDVEQRVLR
                     AADELGYRPNAVSVGLRTGTSRTIGFVSDTVATSRLAGDMIKGALEAARERGVMLFIGE
                     TEGDPELERGLLHAMQDRQVDGLILASMYTRTIKVPKDVGPAVLLNALPKTASDLPSIV
                     PDEVEAGRAAARVLLDAGHRDGIYLIGVGPELGDVPPRSVAARERLVGIREILGEAGVK
                     IAGGRMFVDWLPEEGSAATADLLEQHRPKALICLNDRLALGAYHALSDAGLDVPGDVSV
                     VSFDDHPIASWMRPKLTTVALPHYELGRKAVEVLFAQMGEETGQGEIHRVPMPVRHRES
                     VAAPRV"
     misc_feature    complement(19920..19934)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.96"
                     /tool="antismash"
ORIGIN
        1 gatccggtcc agccagatgg ccgtggaggt gttggccacc gcggaaccac caggctcgga
       61 ggccgcgctg gccgaccagt cggggttcac atagccggtg gcacccgcgt aggggttgtc
      121 gactcggccc gggttgacga tgtcgtcgtc gccctcggtg gcggtgacgg tgacgctggt
      181 caggccggag gaggcgacgg tgatcggccg ggtgccgttg gtctggtcgc tgtcctgcgc
      241 ggcggccagg gtgacggtct gcggggtctg ccagttcgac gtggtgaagg tcaggctggc
      301 gcccgaggag acggtgatgt tggtgtcacc ggagccggcc gtgttggtca cggtcacgtt
      361 gccgctgggc gcggcctgga ggcgcaccgt gtaggtggcg gtgccgccct cggggacggt
      421 cacggcggtc gaggagacga ccagcgcctg ggtctgcgtc acgtcgtcgt cggcctcggt
      481 cgcggtgacg ttgacgctgg tcagaccgct ggaggcgacc gtgaaggtgc gcgagccgtt
      541 ggtcgtgtcg ctgtcctgcg cggcggcgag ggtgacgttc tgcggagtgt tccagttgct
      601 gctggtgaag gtgaggctgg tgccggacgt cgcggtcagg ttggtgtcac ccgaaccggc
      661 ggtcgtggtc acggtcacgt tggagctggg ctgcgactgg agccgcaccg agtaggtggc
      721 ggtgccgccc tcggggacgc tcacgctggt cggcgagacc acgagggcct gctgcgacgg
      781 gctgggcgaa ggcgacgggc tcgggccgcc gttgcagacg gtcccgttca gcgagaacga
      841 ggtcgggttg gtgttggtgc cgctgacctg gccgttgaag ccgatctgca ccgactggcc
      901 ggtgcccagg ctgcccgccc aggagggcgc gaccacggtc acgttctggc ccgactgcgt
      961 ccaggtgccg ttccagccct gctgaaccgt ctggctcccc ggccacgtgt acgtgagccg
     1021 ccacgggttc accgcgtcgc cgaggttgtt gatcgtgatg ttggcgccga aaccgctgcc
     1081 gttgtcccac tgtttggcgt aagtgacctg gcaggccacg gcggcgccgg caggcgcctg
     1141 catgacggcg agcccggtga cggcgagcag catcgcggcc gccaccatca gcgctctgcg
     1201 ccaggaactc aatcggggtc ccatagcttt ctcttctcct cggcgtactc gattgggagc
     1261 gctcccaaca tgagttcgtt tcgccgaggt gtacaggatg tttccgtttt caacgagatg
     1321 tcgcaggacg cctatgaaag attcagagtg cgtgcggcca gccggtggag gtgctgccgg
     1381 aaccgggcca gcacctcggg gttctccggt cccatccggt cgccggcctc gtcgagcacg
     1441 ccgccctgca cgaacccgtg cacacaccag atcagcgtcc agacgcagta ctccatgtcg
     1501 gccgtgtcgt cgatgtaccc ggcgtccgcg gcctgttcca ggacggacgt cgtcatggtg
     1561 atcaagggct gggagtactg ccgctccagg ccggtgaggt cggccgcgtc gtacagccac
     1621 cggtggatcc acagcgccgg gaactccggg tgggcgacgc agaagtcgat atagcggtcg
     1681 acgatctcgt gcacggcgtc cgccaccgag atctggtcgg ccgtcatcat ctcgttgatg
     1741 acgccttcga gctcctcggt ctcgatgcgg gcggcccgct cgatgacggc gagatagagg
     1801 tcccgcttgg accccccgaa accctcctcg gccgggtcga tcccggtcga gtcggcgatc
     1861 tgcttcaagg tcgtggcgtc gtatccgagt gcggcgaaca gccgtgtggc cccctgcagc
     1921 aggctttcca tccagggctc ccgatcccta gttccttacc ttttccaagt ccagcaccca
     1981 gccggtcacg ggagagcaaa cggcgcgctt gaccacggaa tccccttatt tatgggcgtt
     2041 tcatgccttt ctgagatgtt ttactgtctt aggtttgcca tgtcatggtt tggtggctag
     2101 tgtcggtttc gttgccaagt gctgaccatc ccacaacaga gcgcttgacc atcacgtccg
     2161 gtcgccggcc cccagggccc gccggacacc gccacccctg ctgacacgcg tggccgtcct
     2221 gtcgtcgtac ggaagatctc cctttttcat gttcgccatc accggcatcc tgaagaaaac
     2281 gaccgtgacc accgtcctcg ccaccgccgg catcgccgtc gccggcctgg gcgcgaccgg
     2341 cgccgccagc accctggccg cccccccgca cgcgaacccc gtccgcatcc acaccaagcc
     2401 ggccgccatc gtgaagccgc tggagaagcc gctcgtgaag gagccctcct tcgtcaagcc
     2461 ggccgtgttc accggcacga ccaccgcctc ctacttctgg gacgacgcct ccggccgggc
     2521 cggcgacacc ggactgcccg ccagcggcaa gccgatgcag aagggcatgg ccgcctcccc
     2581 cagctggccc ctcgggaccg agggctacgt ggtctacaag ggccagaaga agccgttctt
     2641 cgtcggcgac cgcggaccgg gcgtaccgtc gtcgaagggc gtcatgctcg acctcgacgg
     2701 gcagaccttc gccgagctga ccggcggctc cttcgacatg accaccctgg ccgtgaaggg
     2761 caacggcggc gccggccaca tcccgatcga ataccacatc accaagtggg gcgacggcac
     2821 gggcctcaag gccgcgccgg ttccgttctc cctcggcgcg tggcggcact gagaggtaac
     2881 gatgtgcgtt tcgggcgggg gagctgctaa agttttcctc gcgggcgccg ctagctcagt
     2941 tggttagagc agctgactct taatcagcgg gtccggggtt cgagtccctg gcggcgcacc
     3001 aagcgaaacc cagatcactt agtggtctgg gtttttcgtt tttcctaaag gcgttcaaac
     3061 accagacaga ccgcggtccg acggtgcaga atccgcctgt gatcatgtca ttgggcgacg
     3121 atctagacag ccgggtcaga ggcgccgcca tggcatggct ccgccgacgc tccacgccgg
     3181 agaatcctgt cgtcagtcga gcggaactcc tcggtttcca gttcgaggga cgcaccttcc
     3241 cgctggtcga caaccaactg ggcatccgca agccccaggg gttcagcgcc gcactctcga
     3301 tcctgacgac ctaccggtcg gacggtcgta gcgcacccta cgaagacgcc gtcggagacg
     3361 acggcttact gcgctacaag ttccagggga acccgagcca ctacaccaac gaggggctgc
     3421 ggcaggcgca tcttcagggc gtgccactca tgtggttcgt cggtgtgcag gccggcctct
     3481 atctgccgtt ctttccggta tggatcaccg cggtcgaaga agcggcgaag caggtagcgg
     3541 tggcgctgga ggaagcccag cggatgatgc cggtggaggg ccccgtcagc ccgctcgaac
     3601 gccgctatgc ggaacgcgtc acccagcaga ggctgcacca gccggttttc cggcagcgtg
     3661 tcattcaggc ctatgagacg agctgtgcga tgtgccgtct ccggcaccga tcgcttctgg
     3721 acgcggccca tattctcccc gatcgccaca gccttggcat cgcggcggtc tcaaacgggc
     3781 tcgctctctg caagatccat cacgcggcgt tcgatcagaa catcctgggg atccggcctg
     3841 acttcgtgat cgaggtccgc tcggacatcc ttgaagagat cgatgggccg atgctcaagc
     3901 acggcctcca ggacatgcat gatcagccca tttcgctgcc gcggcaccga gcggatcggc
     3961 ctcatcgaaa tctgatcgaa gagcggtacg agatgttccg cagcgctggt tgaccgcggc
     4021 cgaaggcgat ggttctgccg ttgcggacct tgccggcctt ataggtcacc gtttcgacga
     4081 ccgcgtcctc cgggtcgacg agcgtgatcg tgtcgccgtc gtcgccgagc cacgagtcga
     4141 actggtcgag gtccgggaag cctgccgcga agtagggcgc cagccgccgg aacagcttgg
     4201 gccagatcac cgtcgtgtcg agggcgccgg ccgtgatcgt ggcggggcgg cccgggcggg
     4261 cggagatgcc tcggcggttc agggcggggg aggtccccga gggcctgggg agcgcttcga
     4321 tcagggcggg ggtgtcgggc aggaacttga cggtgtcacc gtcgggctcg gggacctggc
     4381 gcgggagatc ggataatcac caaattgccg tgcaaaagtt tgtatgtcat cgcctgtcac
     4441 cccgtggcga gaatggattc agatccagcc tgcttccgtg gctatgcgta tcgcgtccac
     4501 gcgattcctc gcgttgagtt tggtgacgat tttggtcagg tagtttcgta ccgtcccgac
     4561 cgaaacgtgc atttgcgcgg cgatctcggg gggctccgct cccccggcgg ccaggcgcag
     4621 cacctggatc tcccggccgg acagggggat ctcgccgacg tcccacgcgg tcagcgccag
     4681 ctgcgggtcg atgatcctgc ggccggccgc cacttcccgt acggcctggg ccagccgctc
     4741 cgacggggtg tccttcagca ggaagcccga caccgacacc gacagggccc gccgcaacgt
     4801 gccggggcgg cccaggcccg tcaggatcag ggtccggcac gacgggagtt tggcgtggag
     4861 ctcctcggcg gccgacagtc cgtcgatgac ggggaggtcg acgtcgatca cggcgacgtc
     4921 ggggcggtgc tccagggccg ccggcacgat gtccgcgccg ctgccgacct gggccaccac
     4981 ggtgaggtcg ggttcgatct ccaggagggc ggccagagcg ccccggacga tgcgaacgtc
     5041 ctcggcgagg aggatccgta acgtgagcac gccattcccc cggccggttt caaggtcaaa
     5101 atgaatcttg taccgacgtg gcggaattag gcaatgccgg acattcttga cagagcgtca
     5161 ttatgggatg tcgaccttta acaggaacgt gccggaatct cgtacgcatt tcaacgaacc
     5221 gccgatggag ttgaggcgtt cggccaggtc atccagggcg gtgccgggct ctccgggggg
     5281 cggcagcgcg gggacgccgt cgttccggac cgtcaaagtc acgtcggcgg tcaccacgat
     5341 ctcgcagcac gtcgcggcgc tgtgccgcag gacgttcgtg acggcctcgc ggagcacgac
     5401 cgccagcacg gcgtcgacct cctcggggac ctccccggcg ctcgcgtgga cgcggacccc
     5461 ggccgccgcc agggtcgcgc gggcggtgtc gagttcggcg gcgaacgaca tgtggcggta
     5521 gccgctggcc accgacctga cctcgccgac ggcgcggcgg gcgacgtcca ggacctcggc
     5581 gagttcggcc cgggcgcggt cggccgagcc gggcagcagg cggtaggcgc gttcgctctt
     5641 gaccgtcatg gcggccaggt cctggccgag caggtcctgg agttcgcggg ccacccgcag
     5701 gcgttcccgg gtgaccgcgc cccgggccag ttcgtcgcgg gcctggtcga cctgggcgac
     5761 gaggccgcac agtgagctga tgccgtacac gaccaggccg gtcagcaggg tcgagagggt
     5821 gaggtaggcg gtccactccc ccgggtcgcc gtggaacacc gacagggcgg ccacgctgac
     5881 gccgacggcg gcgtagcagc tccagcgcca cgctccggac aggacgatca acgtggtgcc
     5941 ggccaggaac ccgcccatcg agccccacgg agcgccgatc cacagcagcg gcagatacgt
     6001 cgccaccacc tggaccggca gcgccgcgcc ccggaggaag cccaggatca gcgcgatctg
     6061 cacgcccacc agaacggcca cgcagagcgc gaactccagc aggccgagcg agtcgacgct
     6121 ctgggccagc acgttcacca ccatcagcag gccgtagccg agcagcacga cgatcgcgat
     6181 cgtgcgggcc acccgcaggt gccacggctg gccggtgatc tgggcgaccg tccgcgtcac
     6241 cgggtcgtcg accggcggcg gcgcgggagg ggcgaggggg acctcggcgg tgaaggtgaa
     6301 gcggtcgccg tccaggacgg tggtgcttgt gccgccggcc gcctcgacgc gggccgacag
     6361 gttgtccagg cccacccccg cgtcggggac cggcgccggc gcgtcggcgc cgtcgttgac
     6421 cacccgcagc acgatgtgct cgcccgccag gtcggtctcg acccggcagt gccgcgcctt
     6481 gctgtgccgc agcacgttgg tgatcgcctc gcgcagcacg atggccagga ccgtgtcgac
     6541 ctcctcgggc agcgggcagg gcgacaggct gatctcgacg gccatgtccg cggcgatcag
     6601 catcgactcg gccgaccgca cctcggccgc cagcgacatc ggcctgctgc cgcccgcgac
     6661 gacccggacg tcgccgagcg cctggctcga cagcgtgagc acgtcgcgca gctcccgccg
     6721 ggcgcgctcg gccgagccgg gcagcagccg gtaggccagc tcgctcttca gcgtgagcgc
     6781 cgagacgttg tagccgagca ggtcgtggac gtcccgggcc acccgcagcc gttcctgcgc
     6841 gaccgcgagg gcggccagtt cgccccgggc ggcgtgcacg gtcagcgcga gcgaggccag
     6901 ggagctgagg ccgtagacca tcaggccggt cagggcggtg aagtaggtgc cgtagacgac
     6961 gtcgagcggg gccatcccct tccacgtcag ggcgatcagg acggtggcgg ggacggcggc
     7021 gtacagggcc cagcgcagcg gacccgcgac ggccagcagc atcgaaccgg ccaggaaccc
     7081 ggcggacgac ccggcctgcg gcccggccca caggaacggc gcgaacgtga cgacggcctg
     7141 ggccgacagg gtgagcgcct tcggccgcga ggaccacagc aggacgtccc gggtcgagtg
     7201 gacgagctgg agcccgaacg cggtcagcag acagacgacg aacgcgccga gcggccagcc
     7261 gcgcagcccc tcgtcccaga cgaagatcag ggcgttgaag gtgtacgcgg acagcacggc
     7321 ggcgatgacg gcacgcgcca tcagcccggg tcgcattcct aacgacacca cagggtctcc
     7381 acttaccggg aaatttcggc ttatgcgaga agggcggcgg cgagcatcgg ccagtccgcg
     7441 tcgttgacgg gatactcgtc ctcggcgaag ccgctcccgg cgtggccgac ggcgtagccg
     7501 cagacgctcg actcggtccg ccagtcgagc ccgaacacgt gcgccgcggc gtcgatgtcg
     7561 gggccgtcga tccggctgcc ggacaggccc atggccgtac cggccagcga cagcgtctgc
     7621 accagcgcgc ccgcgtcggt gagcacgagg gagtagccga ggccgttgta cttccacgac
     7681 agccgccgga accgcgcggt gatcatcagc agcaccggcg ggcgggaggc gaggttggcc
     7741 gagacgagca gttcgtccgg gtcgccgtcg agcggggtca gccggtggcc gtaggggtcg
     7801 tagtggtaga ccccccgctc caggccggcg caccggtcga cgacggcgta gagctccagt
     7861 tcgtggcagt cgccgctggt cggcgagggg cggtcgctcg tggtggtggt cgcctccgtc
     7921 gacggcgagc ccctcagcga gcggacccgc gcggtccggt agagcagcgt gcccaggtcc
     7981 tcgaccgtga tcggccgcgc ggcgaaggtc tgggccggcc ggtgggcctc gacgacggcc
     8041 gagaagggcg ggtcgccggc caggtcgggc cacgacggcc ggggcagcgg gatgccgggg
     8101 ccggtctcct tcaccaccgg ctcgacgctg ccgtgctcgc cgagcggata ggtcaccccg
     8161 aagtcctggt cgtggcggcc cagcgtggag cgggtgtgga acatcaggtc gatcggcgtc
     8221 cacgtcgtca gcgcggggtc gttgtcctcg tcgaactcga tccgctggaa cgggtcgccg
     8281 gtcgcggcct gcacgaccat cccggccgcc atcaggaagg cgatcaccga ccgggtctcg
     8341 tgaccgaccg aggccgggac ggtcgggcgc atcagcgtgc cgagatggcc gatcgcgtcg
     8401 gcgcggtgca ggatcacccg atgctgcgac agcggggact ccagcaggta gttggtgccg
     8461 tcggtggtga ggacggcgaa gcgcgacagc cgcaccggat ggaccagggg cccctccggc
     8521 aggtggaagc cggcctgcgg ggtgagcggc acgacggaga ccagcggctg ctcccggtcc
     8581 acgccgaacg accgcacgac cagatgggcc agccggtcga gcagcgcctt cagcgcctgg
     8641 cggtcggcgg acgacctgat gacgttgccg agcgagatcg gccccaggct catccggcgc
     8701 agcgcctcga cgacgggcgg cgcgggcatc gggaagacgg tgtcctccca gcgggagtgc
     8761 acgacgacca cgccctcgtc cgggtcgggc tcgacgaaga cgtcctcacg gaacgaccac
     8821 aacgggaacg gggggagcgt gtcgtgcatg tcggctcctc tcacgtgaac tctcacatga
     8881 acagggcgac cggattcagg tcgtcgtaag cggtcggccg gtcgagccgc cccagcttca
     8941 ccgggacgtc gaacagccgg cccggcgcga accgcggcca gaagtgccgc agccccggga
     9001 cgacgacctt gaccacgggc accccgatgt cgggacgggt ctggtcgagg atgagcggat
     9061 cgtgtttccg gatgaggtcg acgtcggctt tcaggtcgtt gtcgcccgtg tacgaaccgg
     9121 gcgcggccac cccgtcggga agcaggcagg gatgactcag ggtggagacg cggccccacc
     9181 atgggcgcat gtcgatgtcg gtggcggcgg gcaggagctg gccgagctcg gtgagcgcgc
     9241 ggcgggcggc ggtctccgga tcgaggtggg cgccgaagcc gagcatgacc tcgtggccgt
     9301 ccttggtcga cacggcggcc atggccggga tgcccaggtc ggtcgtcagg tcgaggaccc
     9361 acaggtcacg gccgagcgtc gcgtagtcgt cgcgcagccg gtcggtccac gggtcgtcga
     9421 ggacgacctc gggctgacgc gtccggttgt accaccagat cccgaccgcg tcccgttcga
     9481 ccagctcgaa gaagccctgg aggagggcgt cctcgacgga gctcccggcg gcgttgccgt
     9541 tggagtcggc ctgcccgccc tcggagaagt agagcaggtc ggtgggcaga tagcgcttct
     9601 cgccgtcgag ggtgtagagc ggggtccatt cggtggcgcg ggtctcgtcg aagggcgcgc
     9661 gctggcgcgg gtcgaagagc agcaccgcgt cggggtgcac ggcctgcgcg ccgagccccc
     9721 ggtaggagtc gtggacgacg ggttcctcgc cgaggcgcga gccgcagtag cgctcgacgg
     9781 cctcgcacag cgcgcccacc cgggcttcga gcggggtgcc gcccttgccg ccgctgttgg
     9841 cccgcaggcc gctgaccggc agggccaggt tgcggccgga cagataggcg ttgaggaagg
     9901 cgggcgcgcg cgggtcgcgg cggatctcgt cggtgacgcc ggtgaccggg tcggtcaggt
     9961 ggacgtaccg atcccacgtc tcctggagtc ccgccgaccg gtgggcctgc actttgggcc
    10021 tggacgtgat ccgcaccggc ccgccccgga cgtccggtgt cccgcactcc gggcactgcg
    10081 gccgtcgcgt cacggggtgg tgcgccgctt cgagggtgag cgggtcgaac gtccacagcg
    10141 tgtcgagcgg ccgtccggcc agccagcccg cgatcctcgt ggccgcgatc tgggccccga
    10201 ccgaccgcgt ctgcggcagc gaggcgggcg gcgcgagcgt cagcggagcc tgccgccgga
    10261 gcctcagccg ggtggcgaga cactcccagc aggccgactc ccccggccgg aaccccggcc
    10321 cgatccacag atcgggcccg tcgacggcca ccgggagcca gggccgcccg tcggcgagac
    10381 gggcggcgtt caccgaggcc agcgcggggt cgagatagtc gtcgcagacg accaccacgg
    10441 gcccgtcacc gccggtgcgc agccccagtt ccttcaacgc ccgttcgacc agggcggagt
    10501 cgccgagcga gaccacctcg acctcgccgt cgggcagacc gagcccggcc aggtcccagt
    10561 aggcccgcac ctcgggagcc acgtcgacgt cgggctgcgg cgccaccagg tcggcctcgg
    10621 acagtctccc gagcagccgg ccgaggtcgg ccgcgccgag cccggtctgt tcgtgcaggt
    10681 cggccaggtc gtggctgccg tcgaggagag gggcgaccgt ctcgatgtgg tcgccgcgca
    10741 gcgcgaccgt ggcccgcgcc gaggtcaggt agaccccgtc accgggcacg gtcaccgccc
    10801 gccagtgtcg cttgaacccg actttcatcc ggactccctg caagccgata ttcccgataa
    10861 ccctgcgcgt tcgaacgact tcgcgataaa acgaagaaca tggcacagac ggtgaagcgc
    10921 gcttacaagt accgcttcta tccgacttcc gagcaggcgg aggaactctc ccgtacgttc
    10981 ggttgtgtgc gcctggtcta caacaaagca cttgaggaac gcacccgcgc ctacgccgaa
    11041 gggcgcaaga tcggttacga gcagtcgctg cggcatctcc agacggccta tgcgaatttc
    11101 ttcgccggac gtgcaaggca tcccgtggcc aaatccagga agcggtcccg ccgctctgcg
    11161 gaatacacac gctcggcgtt cacgtggctg aacggtgaac tgaaactcgc caagatgcgc
    11221 aagccactcg ccattgtctg gtcgcgacca ctgccggaag gcgctcagcc ctccaccgtt
    11281 catgtgtcgc aggacacggc gggccgctgg ttcgtgtcga tcctcgtcga agagcgtatt
    11341 cgctcgctcg atccggccgg aaccgccgtc ggcgtcgatg tgggaatcac cgacctggtc
    11401 acgctctcga cgggcgagaa gatcgcgaac cctcgacacg cacaggccat gcggcgaaag
    11461 ctgacgaggg ctcatcggac gctgacccgg aagaaaattg gatcgcgtaa tcgggcaaaa
    11521 gcccggctta cgctcgccaa gacgtatgcc cggatgactg accgtcgccg ggatttcctg
    11581 cacaagctct ccacgcgtct cgtccgtgag aaccaaacgg tcgtgatcga agacttgagt
    11641 gttcggtcca tgctcagaaa tcgcacactg tctcgagcca tctcggatgc ctcttggcgc
    11701 gaactccggg ccatgttgga gtacaagacc cactggtacg ggcgcgaact tctcgtcgtg
    11761 agccaatggt ttccctcctc caagatgtgt tcgaactgtg gagcactccg agagaccttg
    11821 ccgttgaagg tccgtacctg ggtgtgcgac tgcggtgtca cccacgaccg ggacgtcaac
    11881 gcggcccgga acatcctcgc cgccgggctg gcggagaggt caaacgcccg tggagccgac
    11941 gtaagacctc agggcgcaag cctctcgggc agccggtgat gaagcaggaa tctcgtggtt
    12001 tcagccgtga gaaaggtcaa ccgcaatacg tccatttcgc cgacaggagc gacggctggg
    12061 tcaggtcggc gatgcgcagc gggtcaccgc ccgccgacag cgggggcgcg tcgccggcgt
    12121 cgaggtcgat gccgaactgg gccagggtgc cggccgggtc gtcttcgtag cgggccgcca
    12181 gggcgggttc ggtccacgcc cgcatcacca gttcggcgaa ccgccagtct tcggtgtgag
    12241 tgatagtggc catggctcga ttctccgcgc gacctccccc acgccgacac tcatcgattc
    12301 acgagacggg tgtgagattt tcacgtcggg aacgtgaaac ggcgtacaga cggccggatg
    12361 taagcgcttc taggctgggc cgcgtgaaaa gcattcgaat ccgccgcccc gtgaggccgc
    12421 ggcccggaac gaaccgggag atcgacacgc gcacgccgtc cggcgtccat ctgccttatt
    12481 aagggaaatg gcatgtatca cgatctgcaa atcaatcggc tgagggcttt ggtgaccgtg
    12541 gtcgagctcg gcgggttccg caaggcggcc gaggcgctgc atgtgaccca gccggcggtg
    12601 agccagcaga tccgtcagct cggcggtctc gtcaaggggc ccattttcac ctcgaccggc
    12661 cgcgtcctgg agctcagcac cgagggtgag gaacttctcg ggtacgcccg ccgcatcgtc
    12721 gccctcaacg acgaggccgt gggccggttc gtcccgccgt cgggcaccgc ccgcctgacg
    12781 atcggggtgg tcaaccagct cgccgaggcg ctcccggaga tcctccgcct gctcaaccgg
    12841 ggcctgcccc acgtgcaggt cggcgtgcag acgggactga gcgagtcgct ggagaaccag
    12901 gtggcctcgg gccagctcga cctggccctg ctcctccagt cggagccggt caccgcgccc
    12961 gcccaccagc tgggcgagat gcgcatggac tggttcggcc gccccgccca cggcgagggc
    13021 gccgcgctgc cgctgaccct cttcaccgag ccgtgcacgc tgcgccgccg catcgtcgac
    13081 gcgctcgacg agtcagaggt gccgtggcgg gtggcctacg agggccccga actcgtcggg
    13141 ctgcgcgccg ccgcgaaggc cggtctgggg gtcgcctgcc tggtggccaa cggcgacgag
    13201 ctgtgggggc tgccccgagc ggcccgcctc gcgctgccca ccgcccccgg cccgctcccg
    13261 gtgacggtcg cgctgtcggc caacgcgacg aactcggagt acgtgccgat cgcggagagg
    13321 gccttccagc aggcgctgcg cgattatccc ttcgcctgac tctcactgat gtggacggcg
    13381 tgacccccag cgcgttcgcc tagctcgtgc accggccgaa catctgcacg tacgtcgcgg
    13441 ccggggtggc cgacaccgac gggtcggcgc tgccgagggc cgccttcgcg tacatctcgg
    13501 tgtagccggg cgtgaggatc gtgtcgcggt ggcgctggct gcccatccac cacgtgacag
    13561 cggcccgggg cgtgaccgac gcccggcccc agccctggta ggcgttctcg ccgacggccc
    13621 aggaggagcc gcgccggcag tacccggccg ccttggccct gtcagccggg tcggtcccgg
    13681 tctccgggtt gatgtggacg tcacagcgcg acgggttgta cttgtccggc gtacagttcc
    13741 cgacctgcgc gaccgtcccc caccagcgga tccggacggc ggcggcgacc tccttcgagg
    13801 cggcgctgga gagcgcgacg gtcgtgccgc gcagggcgat gtagcgcttg accggctgca
    13861 gtccccggct ggtccgctcg gcgttgacca ggcacaggac cgacttctcg atccggctcc
    13921 cctgcatgtg gttgtcgtag cgcccccggg ccgtgtcagg gaaggcggac gcgggctgga
    13981 aaacgaaatc gatgtcggcg caggtcgcgg cgcccgccag gggcgcggcc gccagcgcgg
    14041 gagaggcggg gacggtgacg gcggcggcca cgagagcggc cgccccgagg agcgcgaggt
    14101 gtctcatgcg ctcatggtgc ggcggggcgc ttgccggggg cttgagtacg cctttactca
    14161 tttcgcgaag tggcccgccg gcgagtggcc cgccgcgttt ccgcagttca cagccttggc
    14221 gacggcactg cgggagacct ggtcgccgcg cttcaagcct ggtgcaagga ggcgggccaa
    14281 tcgtgcccat gactcccatt ttcccaggag gaacccggtg tccccgttca agaaggccgc
    14341 cctcatggcc gccgtgacca cctcggcact cgccctcgcc gcccccgcgc acgccgacga
    14401 acccggcgaa ctgaccgccc gcctgaccat caccggaagc ggcagcgagt gccgcgtcct
    14461 gacggtcggc aaggtcggga tgaccaacgc ccaggcgcag tacctcgtcg acaacggcgc
    14521 gaccgcccgc gtcgaggtct gggccgacga cccgatctac gacaaccgcg tctacaaggg
    14581 accggcggcg gccctcagcg cggtgtcgga caagaacggc ggcggcctgt tcatcgtctc
    14641 cgacctgcgc ctgtcctgcg tcaactacct cgacgaggac gacaagccgc ccttcgacta
    14701 cggcgacgag atctacacga agatcgtctt ccagggcccg ggctaccccc gcatgacgaa
    14761 gaagtccaac gtcatccacc gcaacttcgg cttcgccgaa ccgtgacggc cgcctggtga
    14821 cctcggcgtc agccgacggc tgagcgccag gtctggcccg aaggcgagcg catcccgcga
    14881 ccgggcgggg tctttggtgt ggcctggcgg tcggacactg tcgatggccg acctcatctg
    14941 acctgcgcag ccgcccgtgc tccggtgagg ggcgatcgtg ctgtcaggcg gagatcggcg
    15001 gggttctccg cctggccggg gcggccgtgc tgctgcggat catcagttcg gtgcccagtt
    15061 cgacgcggcg ctgcgggagc gtctcgccct cggccatgga gatcagcatg gtggccgcca
    15121 tgacgcccat ctccgtcagc ggctgccgga ccgtggtcag cggcggcgtg gcccagcgcc
    15181 aggcgggcat gtcgtcgaag ccgatgacgc tgaggtcgtc ggggatgcgc aggcccctcg
    15241 cgtaggccgc gtggtagacg ccgaccgcct ggccgtcgtt ggaggcgaag atcgcggtgg
    15301 gcggctcggg caggtccatc aggcggtggg tgtgggtgag gccgtcttcg atctggaagt
    15361 cgccggggca gatcaggtcg gggtcgaccg ggacgcccgc ggcgtcgagg gcggcgcggt
    15421 agccgtccag gcgggcgcgg ccggccagcg cccagtcggg gccggtgatc atcgcgatgc
    15481 ggcggtggcc gagttccagc aggtggcggg tggcttcgag gccgccgctc cagttggtgg
    15541 cgccgaccga cggtacggcc cggccggggt cgcccgccgg gtcgaggacg accagcggga
    15601 tctcccgggc ggcgagccgg gcgcgctgct cctccgtggg gcccgagaag accgtgatga
    15661 ctccggccga acggcggctg agcacgcttt cgagccagcc ctggccgggg acgtgccgcc
    15721 cgccgagctc ggagatcacc aggccctggc gggcctcgcg ggtgacctgc tgaacgcccc
    15781 ggatgacctc tatcgggtag tcaccggcga gttcgtggaa gacgagctcg atgaggcccg
    15841 ccggtttgat ccgccgtcgc tggcggcgga agccgtgttc gtggatgaga ccctcgacca
    15901 tggcgcgggt cttcgggccg acgtccgtct ggccgttgac gaccttggag acggtggcca
    15961 tggagacccc ggccatctcg gcgagctgag agagggtcag cggggccgga gaggccgcgc
    16021 cggtggggga ttcctctgtc ggggtcatat gcggagttta gctacgtggc tttcggtcgt
    16081 attcgcagca gatcacaccg cgcgcttgcc ggagcggccc gaacccgctt ctcgtaaatt
    16141 agtgctcttt tccgcgaatt ctacgtggtg acttctctga aactttcact taacgtcacg
    16201 agcgctccgc gatcttcttc tgtgcgaacg tccaggcagg gaaacgttca gcggacaccg
    16261 gccggaggcg ggcgggatcc cgccgcgttg acggtggatc gcgccgtcgg atgtactccc
    16321 cggcagcaac ccacaggagc caacacgacc gtacgggatc ttgaatgtta gcgataacag
    16381 accccggccc ggccgtctca acctggtcga ggagcaccac cgcaatgact ccccacgcga
    16441 tcctgaccat cgcgcgacgc actctcgtcg ccggcgcggc gctcgtgctc gccgtccccc
    16501 tcaccgcgtc cgccgcggcc gccacgctcg gcgccgccgc ggcccagacg aaccgctact
    16561 tcggcgcggc catcgctgcc ggccggatga acgactcgac gtacatgacc attctgaacc
    16621 gcgagttcaa ccaggtcacc gccgagaacg agatgaagtg ggacgccacc gagccctccc
    16681 ggggctcctt caactacaac aacgccaacc gcatcgtgaa ccacgcgatc agccgaggca
    16741 tgatcatccg tggccacgcc ctgctctggc accagcagat gcccggctgg gcccagggcc
    16801 tgtcgggctc gacgctgcgc agcgcgatga tcaaccacgt cacccaggtc gcgacctact
    16861 tccgcggcaa gatccactct tgggacgtcg tcaacgaggc cttcgccgac ggcaacggcg
    16921 gcgggcggcg gcagtcgagc ctccaggcca ccggcaacga ctggatcgag gccgccttcc
    16981 gcgcggccag ggccgccgac cccggggcca agctctgcta caacgactac aacaccgacg
    17041 gaatcaacgc caagagcacc ggcatctaca acatggtccg cgacttcaag cagcgcggcg
    17101 tgccgatcga ctgcgtcggt ttccagtccc acctgaccaa ctcggcgccg agcgactacc
    17161 aggccaacct gcagcgcttc gccgacctcg gggtggacgt ccagatcacc gaactggaca
    17221 tctccggctc caaccaggcc aacgcctatg ccaccgtcac ccgcgcctgc ctggccgtgg
    17281 cccgctgcaa cggcatcacg gtctggggca tccgcgacag cgactcctgg cgcaccggcg
    17341 cgaacccgct gctcttcgac tcgtcgggca acaagaaggc cgcgtacacc tcggtcctga
    17401 acgccctcaa cgcggccacc cccagcccga ccccgacgcc cacgccgacc ccgaccccca
    17461 cgccgactcc cacgccgacc ccgaccccga ctccgacgcc gaccccgaac cctggcggtc
    17521 cgtgccgggt ggcgtactcg gtcaacccgt ggaacaccgg ctacacggcg gcgatcatcg
    17581 tcaccaacac cgggtcgtcg gcgctcaacg gatgggcact cgccttcacc ctgccctccg
    17641 gccagacgat caccggcggc tggaacgccg cctacaccgg gtcgagcggc cagatcaccg
    17701 cccgcaacct gagctacaac aacgccatcc cggccggcgg ctcggtggag ttcggcttcc
    17761 aggccaccca caccggcaac accgccgccc ccacgagctt caccctcaac ggcagcacct
    17821 gcaccacggc ctgaccggcc cccagaccgg cccgccgccc gtgatcgggg cgggcggcgg
    17881 gccttccaga cagcacgcgc ccccaggagc tccctcccgg gggcgcgtgc tcccacttca
    17941 cctcgtagtc acccgttcgg aacgaccacc gactcccacc ggcggaccag aagcgctgtg
    18001 cgccactccc ggcggctgga ccagctgacg aaggccgcag cgcccacaag ttcggggcac
    18061 cggaaatctc caagtgacgg accggcagat ggagaccggg aagctcagat gtccagcgcg
    18121 ccaccgcttc tcagtgaaag accggcagac cagagaagca aagcctccat gtaggggacc
    18181 ggcgcccact cccggaatga accggctgac aaaggccagg gacggccacc cgatccgggt
    18241 gacgggccag cgagcaaatc caccggctca cacatgtcag gagcggctac cgactccagc
    18301 agcgaaccgg cagccggaaa ccacgaagcc accatgtgcg gagcgccacc cactcctggc
    18361 tgcggtccgg ccgacaaagg ccacaagctc acaccatcag gggcaccggc ccccagcaac
    18421 agaccgccat ccaaagccca cacggtcagg acgcacccgc tcttagtgac gccccccgag
    18481 caaaggccgc agaagtcaca tgttcggagc ggccacccac tcccatcgga aagcaggcaa
    18541 aggccgcaag ctcacacgtt cgggagcacc gactgactcc cagcaacaga ccgccaggca
    18601 gaagccgcga agcccacatc ttcagcacag ccacccacta ccggtgacta accaccaggc
    18661 aaaggccgca gagttcacac gcgcagagcg gcgcccgact ttcggtggct gatcccgggc
    18721 gaggccgaag cgctcacacg cggagaggcg cccgactctc ggtggctgat ccccgggcga
    18781 gacggcagag ctcacacgcg cggagcggcg accgactctc ggtggcggac cggcatcggg
    18841 acgcggtgga tttctccctg tcctgtttcc tcgcccatct gggcgaacag gacctccacc
    18901 gccttgcggc ccagttcgta gtggggcagg gccaccgtcg tcagcttagg gcgcatccac
    18961 gacgctatcg ggtggtcgtc gaaggagacc acggacacgt cgcccggcac gtcgagcccc
    19021 gcgtcgctga gtgcgtggta ggcgcccagg gccagccggt cgttcaggca gatcagggcc
    19081 ttggggcggt gctgttcgag caggtcggcg gtggcggctg agccctcttc ggggagccag
    19141 tcgacgaaca tccggccgcc ggcgatcttc acgcccgcct cgcccaggat ctcgcggatg
    19201 cccaccaggc gttcccgtgc cgcgacgctg cgcgggggga cgtcgcccag ttcggggccc
    19261 acgccgatca ggtagatgcc gtcgcggtgg ccggcgtcga ggagcacccg ggcggccgcg
    19321 cggccggcct cgacctcgtc ggggacgatc gagggcaggt cggaagcggt cttggggagg
    19381 gcgttcagca ggacggcggg gcccacatcc ttggggacct tgatcgtgcg ggtgtacatg
    19441 gaggccaaga tcaggccgtc gacctggcgg tcctgcatgg cgtggagcag gccgcgctcc
    19501 agttcggggt cgccctcggt ctcaccgatg aagagcatca cgccgcgttc gcgggcggct
    19561 tccagggcgc ctttgatcat gtcgccggcg aggcgggagg tcgcgacggt gtcggagacg
    19621 aagccgatcg tgcggctcgt gccggtgcgc aggccgacgg agaccgcgtt cgggcggtag
    19681 cccaactcgt ccgcggcacg cagtaccctc tgctcgacgt cgtgggatat gcgcagctca
    19741 cggcctctgc ccgtcatgac gagcgaggcg gtggtgcggg aaactccggc cgcctgggcc
    19801 aggtcggcca aggtgacccg acgtcgactc acggggggag acctccacat tccaaccgca
    19861 ttacgggccc ttgacaccgt cggatacgca cggtgagact atcgcatcgc taatccgatt
    19921 tagcaaaggg agacgcacat gtctcatcga gttcactccc gccggagccg cgtggcgatg
    19981 gtggtcatcc tggggggaag cctggccgcc gcctgcgcgg cgccgggcag tggcaacgcc
    20041 cagccgacgg ccgccgcgtc gtcggcgccg gcgctggcgt ccgcgccgac ctgcggcacc
    20101 gagcccgtca cgatgaaggg ctacttcgaa acgggtttcc cgatcgcgaa ggcgctgacc
    20161 gacgagttca ccaagcagca cccgaacgtc accttcgaca tccgcgaaga ccagttcgcg
    20221 gtgatcaccc agaacgcgcc gcgcgtgctg gccgacgacc cgccggacct catgcgcctc
    20281 ccgcaggtct ccgagctggt caagaacaac ctgctgaaga acctcgacga gtacgccaag
    20341 gtcttcggct gggacaagtg gccgccctct cagctccagc agatgcggat ggcccccggc
    20401 ggcgcggtgc gcggcgaggg ctccctctac gccatgggcc tcaacttctc catgaccggc
    20461 gtcttctaca acaagaagct cgccgcccag atcggcatga ccactccccc ggcgaccctc
    20521 gccgacctcg acgccgccat ggccaaggcg aaggaggcgg gcctggcccc gatcgcgcag
    20581 ttcaacggcg gcgcgaccgg cgggctggcc ttcccgctcc aggacctgat ggcctcctac
    20641 ggcccggccg cccccatcaa cgactggatc ttccagaagc ccggcgcgac catcgacacg
    20701 ccgtccaacc tccaggccac ccagcacctg gagaagtgga tcaaggcggg ctacttctgg
    20761 aaggacgtca acgccgtcga ctacgccacc atgatgagcc gcttcatgaa gggcgacggc
    20821 cttttcat
//
