LOCUS       NZ_BBXG01000007        22511 bp    DNA     linear   CON 08-AUG-2024
DEFINITION  Herbidospora cretacea strain NBRC 15474, whole genome shotgun
            sequence.
ACCESSION   NZ_BBXG01000007
VERSION     NZ_BBXG01000007.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Herbidospora cretacea
  ORGANISM  Herbidospora cretacea
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Herbidospora.
REFERENCE   1
  AUTHORS   Komaki,H., Ichikawa,N., Oguchi,A., Hamada,M., Tamura,T. and
            Fujita,N.
  TITLE     Genome-based analysis of non-ribosomal peptide synthetase and type-I
            polyketide synthase gene clusters in all type strains of the genus
            Herbidospora
  JOURNAL   BMC Res Notes 8, 548 (2015)
   PUBMED   26452464
  REMARK    DOI:10.1186/s13104-015-1526-9 Publication Status: Online-Only
REFERENCE   2  (bases 1 to 488345)
  AUTHORS   Hosoyama,A., Oguchi,A., Ichikawa,N., Kimura,A., Ohshita,R. and
            Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-MAY-2015) Contact:Director-General Department Of
            Biotechnology National Institute of Technology and Evaluation,
            Biological Resource Center (NBRC); 2-49-10 Nishihara, Shibuya-ku,
            Tokyo 151-0066, Japan URL :http://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Noncontiguous Finished
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: newbler v. 2.6
            Genome Coverage                   :: 71x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001570605.1-RS_2024_08_08
            Annotation Date                   :: 08/08/2024 02:39:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,566
            CDSs (total)                      :: 7,487
            Genes (coding)                    :: 7,430
            CDSs (with protein)               :: 7,430
            Genes (RNA)                       :: 79
            rRNAs                             :: 4, 5 (5S, 16S)
            partial rRNAs                     :: 4, 5 (5S, 16S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 10 of 57
            Pseudo Genes (incomplete)         :: 49 of 57
            Pseudo Genes (internal stop)      :: 3 of 57
            Pseudo Genes (multiple problems)  :: 4 of 57
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:10:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 162835
            Orig. end                         :: 185346
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBXG01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22511
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22511
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22511
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12511](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12511
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(1021..1896)
                     /locus_tag="AW270_RS15270"
     CDS             complement(1021..1896)
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546783.1"
                     /locus_tag="AW270_RS15270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar kinase"
                     /protein_id="WP_061294993.1"
                     /transl_table=11
                     /translation="MTELFTLGEVLGVVTADRIRHDMSARLDLEGPELTVAVGLARLGH
                     SVAYVGRVSDDEIGVRTSTVLRGEGVDVSHMRVDETAASGLALRQRRIGRVAHAVFYRE
                     GSAGSRLSTGDVPTALQDARILHVSGITPALSGFAWSAVHHAVKLARDAGVLVSVDVNH
                     RANLWDSVEEAREGLRELSASADILFANQDELSLVEPALARVPELVVMRGSKGASATVE
                     GFRYDTQAAPVTVVDATEVGGAFVAGYLSAHLDGVHPSDRLKRGIAVAAFAVASHSTWQ
                     GLPNRSELPP"
     misc_feature    1871..1886
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     misc_feature    1932..1946
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     gene            complement(2009..2437)
                     /locus_tag="AW270_RS15275"
     CDS             complement(2009..2437)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW270_RS15275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_061294994.1"
                     /transl_table=11
                     /translation="MVLLGLLLIVVAGAVLIEISIQDTTATASTPISVFDWNFTLTAFE
                     MFLLGAATAAGVLIGLAMVSGGMRRSVTKRRRLREERLAERDRVSRLESEKRNLERKLV
                     DQNHNGVDDRDETRPVDRAEDNDQLVAGGRHSRRDDAF"
     gene            complement(2490..2714)
                     /locus_tag="AW270_RS15280"
     CDS             complement(2490..2714)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW270_RS15280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_061294995.1"
                     /transl_table=11
                     /translation="MRPGRLDRPLTLPGLSRFAEEYTTIERMGRLAAEAYRLRTELGGA
                     ERRDLFTALAGPAEVAPRRKERAWADMNG"
     gene            3007..3210
                     /locus_tag="AW270_RS15285"
     CDS             3007..3210
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW270_RS15285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_061294996.1"
                     /transl_table=11
                     /translation="MSELQQVEEEIARIRAEARSLREQIGDRAGDGPADSAELSSLIAN
                     ADQLDTLAEELEGRREALKSQG"
     misc_feature    3666..3686
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.25"
                     /tool="antismash"
     misc_feature    complement(3880..3893)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.74"
                     /tool="antismash"
     misc_feature    complement(3886..3895)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.59"
                     /tool="antismash"
     gene            3911..5218
                     /locus_tag="AW270_RS15290"
     CDS             3911..5218
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546769.1"
                     /locus_tag="AW270_RS15290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_061294997.1"
                     /transl_table=11
                     /translation="MSHPPRRRAARLLVLLIAASLLAACGGGENTPAPGAASGSAAPAN
                     TEPVKLTVALFSDFHYGPLYEEFKKTHPNVEITERRAQFNDHHNNLVTQVATGAGAADI
                     VAVEGGFIATFREVADKFHNLNDYGLNSRQSEYLDWKWQLGLSKDGSQLIGLGTDVGGL
                     AMCYRPDLFKEAGLPTNRDEVSALWPTWEQYVETGKKFVAAGGKAAFTDGPGEHFRAMV
                     EQAPVGFYDTSDKVVVGSNPDVRKAWDVAVSMIQNKLSGKLTAFTPEWTTGIAKGTFAT
                     MVCPAWKTGVIKDQKPGEGTWDIAAVPGGGGNQGGTHLLAPKQGKHPKEAAELINFLTS
                     KESQLSLWKDASALPSLPALYTDPAVADFVNPYFGDAPIGKIFTDAAKALKPQYTGPKS
                     GDVNVAMGNGLGRIELQGQDPEEAWKQAVADSEKIK"
     gene            5277..6242
                     /locus_tag="AW270_RS15295"
     CDS             5277..6242
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893596.1"
                     /locus_tag="AW270_RS15295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_061294998.1"
                     /transl_table=11
                     /translation="MATRAPERPAPPRRPGGKRRLTARHWRHTVDVKASPYAYVAPFFL
                     LFCAFGLFPIGYTLWVSLHEWTLLDDEHTFVGLENFRVLLADSYFWNATFNTLSIGLLS
                     MLPQLLLALWLAHLLNRPLRAQNFFRITLLLPNVTSVVAVVVIFSQIFGRDFGLINWVI
                     TSFGLDGIAWRDGTLSSHVAISTMIMWRWTGYNALILLAAMQAVPRELYEAATIDGASS
                     FTQLRKVTVPMIRPTIAFVVITSTIGSMQIFAEPLLFGAYTLTGGQDRQYQTLSLFFYE
                     NYMRLDFGFSSAISWMIFVFILIIAGINYLLTNRMKGSIR"
     gene            6239..7063
                     /locus_tag="AW270_RS15300"
     CDS             6239..7063
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131097.1"
                     /locus_tag="AW270_RS15300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_061294999.1"
                     /transl_table=11
                     /translation="MTGRRVNNRLTYLTLTAVAFFFTIPLYYSVVVASRDNASLASVPP
                     PLFPGGNFFENVSRVFDTVPFGLAMLNSVLVAGSISISVMFFSTLAGFAFAKLRFRGRN
                     ILLLMTVGTMMVPTLAGIIPLYILMVKLEWVGSLYAVVVPALVNAFGVFFMTQFLSRAL
                     PTELLEAGRVDGCTTWGLVWHVVFPAARPAAAVLGMLTFMTAWNDYMWPLMVLTPENPT
                     VQVALSTLAAGYVNDYVMGLAGTALGTLPLVIVFALLGKHIIGGIMQGAVKG"
     gene            7060..8433
                     /locus_tag="AW270_RS15305"
     CDS             7060..8433
                     /EC_number="3.2.1.21"
                     /GO_function="GO:0008422 - beta-glucosidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030245 - cellulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889988.1"
                     /locus_tag="AW270_RS15305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GH1 family beta-glucosidase"
                     /protein_id="WP_061295000.1"
                     /transl_table=11
                     /translation="MTPDIEFPEGFIWGAATASYQVEGAAREDGRGVSIWDTFARTPGK
                     VADGHTGDVACDHYHRYPEDVRLMADLGLDVYRFSTAWPRVVPDGSGPANPRGLDFYDR
                     LVDELLAAGITPYVTLYHWDLPQNLEDRGGWTSRDTAYYFADYAAAVHARLSDRVSTWT
                     TLNEPWVSAFLGYGSGVHAPGVTDPAAAFKAAHHLLLAHGLAAQNLTGTLALTLNMAPV
                     VTPAQILDAGIALSGEDSAAVHLVDALLNRQFLDPALKGTYPAEVLEIAERHGGLDHIR
                     DGDLDIICQPIDLLGINYYNPCVVQAAAGAVAPTAWPGTDGVEFAVIEGPQTSMGWPII
                     PSGLSRLLVRLSRDYPDVGLLVTENGAAFHDKVVGDRVPDSDRVSYLDGHLRACHEAIA
                     AGADLRGYLVWSLFDNFEWAEGYHQRFGIVRVDYATQRRLPKDSALWYRDVIQRNGIE"
     gene            8430..9425
                     /locus_tag="AW270_RS15310"
     CDS             8430..9425
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131095.1"
                     /locus_tag="AW270_RS15310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_061295001.1"
                     /transl_table=11
                     /translation="MKRPTLEAVAARAGVSKSTVSRVVNGDTTVTPNFRELVLRAVNEL
                     GYVPNSVARSLVTQRTNSIALVVSDPPAGLFSDDPMFSAVVRSASRALEAASKQVVLML
                     AGSDESRVRVQEYVAAGHVDGVMLVSFYGADPLPAALMRMGLPMASFGKPVSAPSVPYV
                     DNDNLGGARQAVEHLLARGRRRIATISGPLDMIASQDRLTGYRETLRDTGRRSIIAVGD
                     FTRVSGDQAMCQLLEDDPGLDAVFAANDLMAIGALHALRRAGRRVPDDVAVVGFDDIEA
                     ALYTDPPLTTVRSPMADQALAVVSLLLGLFEDGPADPVILPTELVVRESG"
     gene            complement(9426..9839)
                     /locus_tag="AW270_RS15315"
     CDS             complement(9426..9839)
                     /GO_function="GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653514.1"
                     /locus_tag="AW270_RS15315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CoA-binding protein"
                     /protein_id="WP_061295002.1"
                     /transl_table=11
                     /translation="MGDRFADLTVIRRLLNETTTWAFVGLSGDPGRTVYNQAQLMKQRG
                     KKIIPVHPDGRPVLGETTYRTLAEIPVPVEVVAIYRRTAFAGGMIDEAVEIGAGAVWLP
                     LDVYDEEAGDRALAAGLDVVMNRCPAVEWALRR"
     misc_feature    9808..9823
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.51"
                     /tool="antismash"
     misc_feature    complement(9809..9829)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
     misc_feature    complement(9838..9854)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.35"
                     /tool="antismash"
     misc_feature    9940..9953
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.0"
                     /tool="antismash"
     gene            10001..12511
                     /gene="lanKC"
                     /locus_tag="AW270_RS15320"
     CDS             10001..12511
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012892882.1"
                     /locus_tag="AW270_RS15320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_082801571.1"
                     /sec_met_domain="micKC (E-value: 5.5e-221, bitscore: 730.8,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 5.1e-16, bitscore: 53.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 1e-07, bitscore: 27.1,
                     seeds: 156, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.9e-06, bitscore:
                     21.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVNDQYELYCLADRLFYDTPDRRGTEIPDFAVAGRDVPRGWSHQ
                     PSDTWFHYAPTGHDVPPQGWKIHVSAGLADAARVLEIVWDYCVERDIPFKFLRSRSVVT
                     MLNSKGASRGASGKLVTIYPRQDCLELTLKELDGLLAGVRGPYILSDLRYGDGPLFVRY
                     GGFVARRCAAPNGELVPAMENDRGELVPDERGPSFTIPPWVTLPDFLHAHLEARNAVTT
                     TELPYAVDSVMHFSNGGGVYLATDRRTGERVVLKEARPMAGLDASERDAVARLQHERDV
                     LRRLDGLDCAPGYRDYFVLGDHHFLVMEFVDATPLQRTLVRTFPLTRADASAGSIAEYT
                     VWALDTLPKVQAAVAALHERGVVFCDLHPNNILITPDGRLVLIDFEVATFAEDLGRSVL
                     AHPAFQAPADRRGTDVDHYALACLTLGLFAPQLTITVPLARAKAAQLGQMIVDTFPVPA
                     ELIKRAVHTITGALGGGPTVSVTSGDPMTAMARAILASATPHRADRLFPGDVAQFRPGG
                     GINMAHGAAGVLFALDASGAGRFPDHEEWLLRQQGEAPPGFYDGLHGVAYVLDRFGHVD
                     RALDLVDRAMAGPWRDLDLSLWSGLPGIGLNLLHLGLDAQPLVELCADRLPADVPEISG
                     GANPRAGLLHGLSGPALLFLRAYDHTRDPALLDLAEHALRLDLKRCTTTADGSLQVDQG
                     WRTLPYLDEGSVGIAIALADLLRHRPGSPLAAALPDLVKVGRCRFFVQPGLFSGRAGMI
                     LADRTLIPGLDWHILPYRDGIAFPGDQLLRLSMDFATGTAGVLYALSGNPLPFTHPLGA
                     EPHAVPGGAPPHPPAKEVIGAPNS"
     gene            12571..12717
                     /locus_tag="AW270_RS38750"
     CDS             12571..12717
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012892884.1"
                     /locus_tag="AW270_RS38750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_157522003.1"
                     /transl_table=11
                     /translation="MVLLDLQAMELPGGGHPGGGGHGGGGSTLTLLGCASQTPSNLSLL
                     LCH"
     CDS_motif       12571..12618
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVLLDLQAMELPGGGH"
                     /locus_tag="AW270_RS38750_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12619..12717
                     /prepeptide="core"
                     /locus_tag="AW270_RS38750_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="6.10"
                     /molecular_weight="2837.2"
                     /monoisotopic_mass="2835.4"
                     /core_sequence="PGGGGHGGGGSTLTLLGCASQTPSNLSLLLCH"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVLLDLQAMELPGGGH"
                     /leader_location="[12570:12618](+)"
                     /alternative_weights="2855.2"
                     /alternative_weights="2873.2"
                     /alternative_weights="2891.2"
                     /alternative_weights="2909.2"
                     /alternative_weights="2927.3"
     gene            12820..14415
                     /locus_tag="AW270_RS15325"
     CDS             12820..14415
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012892885.1"
                     /locus_tag="AW270_RS15325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_061295004.1"
                     /transl_table=11
                     /translation="MRTADRLTAEAIRRSGPAAGVLAAVALAGAGLELALPFVLGRAVD
                     TFSPSWVALAGAVVVLLVACDGLGVYASGTGGARAAAWLRHRTLTHLLGVGPGVTRRIP
                     EGDLVTRLGVNAEEAGRAGDAMVASVALVVPSAGALVLLVLIDPWLALTLAGGLVVIAF
                     VLKRFLKTSTVIAGGYQEAQADIASRLVEAVAGARTIAAAGTAERETSRVLTALPVVRG
                     HAMALWRANADAGARAAIVVPLLEVLVLAVGGWRLSAGELSVGELYAAARYVVIGAGLG
                     PAIGSLGRLARARAAGARLAEILDECPRTHGVRTLPAGPGRLTFHDVPGLALEIPGGAS
                     VAVVGAGAARFARLAARLDDPESGEVLLDGVPLRSLTRASLRAAVGYAVARPHLVGDTV
                     ADAIGGSRPAAVAAGADDFVRRLPHGYQTALAEAPLSGGERQRLGLARAFAKGNRLLVL
                     DDATSSLDTITERQVSNALSADARTRVTVTHRAAVAARADRVVWLHDGRLRGFDRHLAL
                     WHDPAYRAVFQGGA"
     gene            14412..16061
                     /locus_tag="AW270_RS15330"
     CDS             14412..16061
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653862.1"
                     /locus_tag="AW270_RS15330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_061295005.1"
                     /transl_table=11
                     /translation="MTSFGRRTRVGPFLWRSFHAQPGQARRFVLWSLVEAAPAFVIGLA
                     IARAVDAFTAQRAVAGLSWTLLLGVSWVFAAVGARQVVVTLATIVEPVREGLLTATVRG
                     ALESGKDDPAAVTRANLQVEVARDAFTGVIGSVKAFVFALLGVVAGVAALMPELLLLVL
                     PPLLLGLGAFLFSLPELARRQHGYLLADEATAESLVRVTAALGDVAASGEEEHAARYAG
                     ARFDGQRRAARRLAGVTTLRTVVLGAGAWAPILLVLAYGPRLGATPGVVLGTLAYVMQS
                     LTPALFNLASGLGESGVRLWVTLTRLRAALPPPAQETRRAEGVHTELKGVTFAYGPQAL
                     PVVDHLDLVIAEGEHLAVVGPSGIGKSTLAALIAGMVAPGQGRVIVGGVPAARVDRGQR
                     ALIPQEAYVFRGTVAENLGDHEPRRMREALDALGAGHIRLQSAATELGPSDRQLVALAR
                     AYLADAPLVILDEATSCLDPAAEALVEQAFAARGGTLIVVAHRVSSALRARNVLVMDGT
                     RVVTGTHQELLAASPLYADLAGHWDPRLRQVS"
     gene            16058..17950
                     /locus_tag="AW270_RS15335"
     CDS             16058..17950
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009076002.1"
                     /locus_tag="AW270_RS15335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prolyl oligopeptidase family protein"
                     /protein_id="WP_061295006.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 4.6e-50, bitscore:
                     165.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDIIHGHVVADPYRWLEDPGSDETRAWQAQQEAVWQSQLLPERD
                     RFRARIDELSDTGVVGAPIWRAGTAFRVRRDPGRRLPVLYADDRPILDPEAIDPGATTL
                     LEAWHPSPDGTLVACQLSRGGDERSELYVIDARTGGLVGGPVGGLRRSPVAWLPGGDGF
                     YYVRDRRARLHRLGGDDLDVADADGLALSADGRWLTLSVNRGPGNDVWLCDLVSPARRV
                     VQQDVAARSAVAVGGDGRAYMITTLDAPRGRLRVADPAAPHDFRDLVPEDAEAVIADFA
                     LLDGVLLVAWVRHAIGEISVHDPETGERQGAVPLPGLGSIGRMSARDHEVWFTYSDYVT
                     PESVYRYDARTGETTLWEAAPGRAELPEIESHQVVYQSADGTPVRMVVLSRGLPGPSPC
                     VLYGYGGFGVPLTPSYSSYVLPWLEAGGVFAFAQVRGGGEEGEGWHRAGMRGRKQNSFD
                     DFAAAAETLIAAGWTRPDLLGVTGESGGGLLVGALVTQRPELVAAAVCSAPVLDMIRFE
                     RSGLGASWVPEYGSADDPEQFAWLLAYSPYHHVKEGVDYPATLFTVFDGDSRVDPLHAR
                     KMCAALQGATSGVRPILFRHEAGVGHAGRSADRAAGLAADMLAFLARELGLDQG"
     gene            complement(17958..18446)
                     /locus_tag="AW270_RS15340"
     CDS             complement(17958..18446)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889839.1"
                     /locus_tag="AW270_RS15340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_082801572.1"
                     /transl_table=11
                     /translation="MNGSGNVTTLDSIDTTITTDLRAARVARLAGGRDQIVLARRLVSA
                     TIGRDHPLHDDCVLLTSEIATNAVVHSRSGDGGVFTVTVWFSSDEVRVCVQDDGSAEPP
                     CAGHSTATATNGRGLPLLDALADRWGIVREGGRNKVWFEMSLTTAPPAAMALLLQRSA"
     gene            18561..19364
                     /locus_tag="AW270_RS15345"
     CDS             18561..19364
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630442.1"
                     /locus_tag="AW270_RS15345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PIG-L family deacetylase"
                     /protein_id="WP_061295007.1"
                     /sec_met_domain="PIG-L (E-value: 1.6e-29, bitscore: 98.2,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTLMAVHAHPDDEVMGTGGIFAKYAAEGVRTVLVTCTNGDQGDG
                     PGGVKPGQPGHSEADVVKQRLAELAESVGHLNIGHVELLGYRDSGMDGWDGNASPDAFA
                     NVDFDQAVAKVAALMAEYRPEVVVTYDENGNYGHPDHIQAHRVAVAASDATGIPVKFYY
                     TAVPRGVIQASVAAMKEQGMDPGWEVPDDFGTPDELITTVVDTHEQAEAKVAALRAHAS
                     QGDSIALLSMPPEMQRMAMSTEHFVRVFTKVPAPDREDDLFAGLR"
     gene            complement(19498..20682)
                     /locus_tag="AW270_RS41795"
     CDS             complement(19498..20682)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541059.1"
                     /locus_tag="AW270_RS41795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_061295008.1"
                     /transl_table=11
                     /translation="MGPADPIRTIEAVWRIESAKVIATVARMTGDIGLAEESAQDAFVL
                     ALEAWPRDGVPDNPGGWLTTTAKRKAIDQLRRQGVYEEKLRELALLPEPSPEPELLTLI
                     FTACHPDVAVEGRLALTLRLLGGLTTAEIARAFLVPEPTVGQRIYRAKTALRKVPIELP
                     PAEELPARLASVLEVIYLIFNEGYAATAGDSWTRNDLCFEALRLSRVLAALMPSSSEAL
                     GLQALLEIQSSRLAARVGPGGEPVLLPDQDRTTWDRLLIRRGLSALARAESTGTLGPYG
                     LQAAIAAVHARALTFADTDWARMAALYQLLAHVAPSPIVELNRAVAVGLAEGPEAGLKI
                     VDNLKLEGNPHLAAVRGDLLERSGRAEEARAAFRQAADLTRNAQEKALYERRAR"
     gene            complement(20687..21034)
                     /locus_tag="AW270_RS15355"
     CDS             complement(20687..21034)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540948.1"
                     /locus_tag="AW270_RS15355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YciI family protein"
                     /protein_id="WP_061295009.1"
                     /transl_table=11
                     /translation="MRYLITLTRTAQPETPPPAELMAAIMQLGREATESGVLVDQSGLS
                     AMAGQVEVVGGKLTVTDGPFAEAKELISYAIYEVRDAAEAVEWANRFMKLHRDMWPGWE
                     GVSHVYPLMTF"
     misc_feature    complement(22469..22484)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.19"
                     /tool="antismash"
ORIGIN
        1 tgggagcggg tcaactggta cggtgcggcc accactgacg cgccgcggcc gaagggctgg
       61 gccgggcgga tctggtcgcc ggcggtccgg gaggagtgcc tggccactgc caacgcggcc
      121 gggctgttcg accagacctc gttcgccaag ttcgacctgc gcggcttcga gccgctccag
      181 gcgctggccg ggaacgacct cgaccgcccg gtcggcacgg tcgtctacac ccagctgctc
      241 aacgcgcgcg gcggcatcga cgccgacgtc acgatcaccc gcctcggcga cgactggttc
      301 cggctggtga cgggcaccgc cttcggcggc cacgacgcgg cgctgctgcg ccggaacggc
      361 gtcgacgtca ccgacgtgac ctcggcccac gcctgctact gcctgtgggg accggcctcc
      421 cacgacatcc tgagcagcct gaccggcgac gacctgggct tcggctacat gcagtcgcgg
      481 gagatcagcg tcggctatgt gccggtccgc gcccagcggg tgaccttcgt cggggagtac
      541 ggctgggagc tctacacgcc ggtcgagttc gggctgaccc tgtgggacac gctgatggag
      601 gccggggccc cgctcgggct gcggcccggc ggctacaagg cgatcgagtc gatgagactg
      661 gagaagggct accgggtctg gggctccgac atcacgccgg agacgacccc gttcgaggcc
      721 gggctgggct tcgccgtcag gaagacgctt ccccgcaccg aatcggcggt cgaactcgcc
      781 tgcctcgtcg tcgacgaccc gtcggaggtc tgcctcggcg gcgagccggt gcgggtcgac
      841 ggggcgccgg cctcgcgggt cacctcgggc ggctacggcc accggaccga cacctcgatc
      901 gcctacgcct acctgcccaa gggcgtgacc agggtggagg tcggcgtgaa cggcggctgg
      961 acgggggcct ccgtccatcg cggcggcccc gtctacgatc cggcgaacct cagggtgaga
     1021 tcacgggggc agttctgagc ggttgggcag gccctgccag gtcgagtggc tggccacggc
     1081 gaacgccgcg accgcgatgc cgcgcttgag gcggtcggag gggtggaccc cgtcgaggtg
     1141 ggcgctcagg taaccggcca cgaacgcgcc gccgacctcg gtggcgtcga cgaccgtcac
     1201 gggggcggcc tgggtgtcgt accggaaacc ctcgaccgtg gcgctcgcgc ccttgctccc
     1261 gcgcatcacc acgagttcgg gcacccgcgc gagggcgggc tcgaccaggc tgagctcgtc
     1321 ctggttggcg aagaggatgt cggccgaggc ggagagctcg cgcaggccct cgcgggcctc
     1381 ctccacgctg tcccacaggt tcgcccggtg gttcacgtcg accgagacga gcactccggc
     1441 gtccctggcc agcttcaccg cgtggtggac ggcgctccac gcgaacccgc tcagcgccgg
     1501 ggtgatgccg gagacgtgga ggatgcgggc gtcctggagg gccgtcggca cgtcacccgt
     1561 cgacaaccgc gacccggccg agccctcgcg gtagaagacg gcgtgcgcga cccggccgat
     1621 ccggcgctgg cgcagggcca ggccgctggc ggcggtctcg tcgacgcgca tgtgggagac
     1681 gtccacgccc tcgccacgca acaccgtcga ggtgcggacc ccgatctcgt cgtcgctgac
     1741 ccggccgacg taggccaccg agtgcccgag ccgggccagg ccgaccgcca cggtcagctc
     1801 cgggccctcc aggtcgagcc gggcggacat gtcgtgccgg atccggtcgg cggtcacgac
     1861 gcccagcacc tcgccgagcg tgaacagttc ggtcatacgc actcttctcc gctattgatc
     1921 ggaagaagca tggcagaacc gttccaatgc cgggaatggt gtcggccccc gcccatggag
     1981 gaggcggggg ccgaagatcg gtgagtgctc agaaggcgtc gtcgcgccgg gagtgccggc
     2041 cgcctgccac gagctggtcg ttgtcctcgg cgcggtcgac cggccgggtc tcgtcgcggt
     2101 cgtcgacgcc gttgtggttc tggtcgacga gcttgcgctc caggttccgc ttctcgctct
     2161 ccagccggga gacgcggtca cgctcggcca gccgctcctc gcgcaggcgg cggcgcttgg
     2221 tcacgctgcg gcgcatgccg ccgctgacca tcgccaggcc gatgaggacg cccgccgcgg
     2281 tggccgcgcc gagcaggaac atctcgaagg cggtgagcgt gaagttccag tcgaagacgg
     2341 agatgggggt ggaggccgtc gcggtggtgt cctgaatgga gatctcgatc aagactgcac
     2401 ccgcgaccac gatcaggaga aggcccagaa gaaccatgtg ttctcacctc gaatgcagat
     2461 gtggcgtggc ccactcgtct gcccgcgaat cagccgttca tgtctgccca ggcccgttct
     2521 ttccggcgcg gcgccacctc cgccggcccg gccagggcgg tgaacaggtc gcggcgttcc
     2581 gccccgccca gttcggttct cagcctgtac gcctccgcgg ccagcctccc catccgctcg
     2641 atcgttgtgt actcctcggc gaaccggctc aggccgggga gcgtgagagg gcggtccagg
     2701 cgccccggcc tcacggtggg ccgccgccgc ttcgggctgg ccccagcgcc gccgggatga
     2761 aggattccgg ctggaaccgg ggcgtcgggg aaggtcggag atcgcgtacc ggaaaccgat
     2821 gccgccgctc agaccggctc atatcgcctc cgagagcgga atgcccgact gctggagcat
     2881 ccggctcacc aggccgccgc gtggtgggtg ccgcctccgg tcggcgggga ccacggatga
     2941 gggcgtcatc tcccggtttt acatcgggcg atccatgaac tccatttgac cgggtagggg
     3001 gctttcatga gtgagctgca gcaggttgaa gaggagatcg cccgcattcg cgccgaggcc
     3061 cgttccctgc gggagcagat cggcgaccgg gcgggtgacg gcccggccga ctcggccgag
     3121 ctttcctccc tcatcgccaa cgccgaccag ctcgacaccc tcgcggagga gctggaaggc
     3181 cgacgagaag ccctgaaatc ccagggctga caccccgtga tccgcgctgc cccggtcggc
     3241 gcggacagtg tcaccatgac ccgcttacgc cgacgtcgaa ggccgtgacc agcggcgttc
     3301 ggtcgcgttg agagcggtga ccgacggcgt tcggtggcgt tgagagcggt gaccgccggt
     3361 tggcggaagt gtgatcggtg gcgttcggtg ccggttgggt ccggcgcgac ccttccggca
     3421 ccgacggtcc ggtactgctc gcaccttctt gccacgcatc ccgcagtgcc tcctgcggtg
     3481 attctgcggt gtcctccgca gtgcctcctg cggtggaccg tcgagcgcgc cctgtctccg
     3541 gccccgcgtg cctgaccacc tgggctgatc tccccatggg acctcctcgg cggaaagacg
     3601 gcgctgagcc gtgcctgaga gaacagaaag cgctctcgcg gcaggatcgt cctgccgaat
     3661 ctggactttt gtcaagacta ggattaactt gcgggaaatc cagtgacaat cgagaaagcg
     3721 ctctacctga ttcaggagat ccctgatgca cgcctgtgaa ctgctgaaac acgtgaaaac
     3781 gccagggaac gttccctgga ggtcacgacg atcgttatct cgcagcccat tgacaacccc
     3841 ctgggcccag ctcgaccctc actccaggga acgttctctt catgatcaaa aataggaagg
     3901 ttccatcggc atgtctcacc cccctcgccg ccgtgccgcg cggctgctgg tgctcctgat
     3961 cgccgcttcc ctcctggccg cctgtggtgg tggcgagaac acgccggccc cgggcgccgc
     4021 cagtggttcg gccgctcccg ccaacaccga gccggtcaag ctgacagtcg ccctcttcag
     4081 tgacttccac tacgggccgc tgtacgagga gttcaagaag acccacccga acgtcgagat
     4141 caccgaacgc cgggcgcagt tcaacgacca ccacaacaac ctggtcaccc aggtcgccac
     4201 cggcgcgggc gccgccgaca tcgtcgccgt cgagggcggc ttcatcgcca ccttccgcga
     4261 ggtcgccgac aagttccaca acctgaacga ctacggcctg aactcccgcc agtcggagta
     4321 cctcgactgg aagtggcagc tcggcctgtc gaaggacggc tcccagctca tcggcctcgg
     4381 caccgacgtc ggcggcctgg ccatgtgcta ccggcccgac ctcttcaagg aggccggcct
     4441 gccgaccaac cgcgacgagg tcagcgccct gtggccgacc tgggagcagt acgtcgagac
     4501 cggcaagaag ttcgtcgccg cgggcggcaa ggccgccttc accgacggcc ccggtgagca
     4561 cttccgtgcg atggtcgagc aggcccccgt cggcttctac gacaccagcg acaaggtcgt
     4621 cgtcggcagc aaccccgacg tgcgcaaggc ctgggacgtc gccgtctcga tgatccagaa
     4681 caagctgtcg ggcaagctca ccgcgttcac ccccgagtgg accaccggca tcgccaaggg
     4741 caccttcgcg accatggtct gccccgcctg gaagaccggc gtgatcaagg accagaagcc
     4801 cggcgagggc acctgggaca tcgcggccgt gcccggcggc ggcggcaacc agggcggcac
     4861 ccacctgctc gcccccaagc agggcaagca ccccaaggag gccgccgagc tgatcaactt
     4921 cctgaccagc aaggagagcc agctctccct gtggaaggac gcctcggccc tgccgtcgtt
     4981 gcccgccctg tacaccgacc cggccgtcgc cgacttcgtg aacccctact tcggcgacgc
     5041 ccccatcggc aagatcttca ccgacgccgc caaggcgctg aagccgcagt acaccggccc
     5101 caagtcgggt gacgtcaacg tggccatggg caacggcctc ggccgcatcg agctccaggg
     5161 ccaggacccc gaggaagcct ggaagcaggc cgtcgcggac tccgagaaga tcaagtagcc
     5221 gtacgccgcg gggtggcccc accggggtca ccccgccttc cctcgaaagg agcgccatgg
     5281 ccacgcgtgc cccggaacgt cccgcgccgc cacggcgacc gggaggcaag cgccggctga
     5341 ccgcccgcca ctggcggcac accgtcgacg tcaaggcctc cccgtacgcg tacgtcgccc
     5401 cgttcttcct gctgttctgc gccttcgggc tcttccccat cggctacacg ctctgggtga
     5461 gcctgcacga gtggacgctg ctggacgacg agcacacctt cgtgggcctg gagaacttcc
     5521 gggtcctgct ggcggactcc tacttctgga acgccacgtt caacacgctg tcgatcggcc
     5581 tgctgtcgat gctgccgcag ctgctgctgg ccctgtggct ggcccatctg ctgaaccggc
     5641 cgctgcgggc gcagaacttc ttccggatca ccctgctgct gcccaacgtc accagcgtcg
     5701 tggcggtcgt ggtgatcttc tcgcagatct tcggccgcga cttcggcctg atcaactggg
     5761 tcatcaccag cttcggcctc gacgggatcg cctggcgtga cggcaccctg agctcccacg
     5821 tggccatctc gaccatgatc atgtggcggt ggacgggcta caacgcgctc atcctgctgg
     5881 ccgcgatgca ggccgtaccg agagagctgt atgaggccgc caccatcgac ggcgcgtcga
     5941 gcttcaccca gctccgcaag gtcacggtgc cgatgatccg gcccacgatc gcgttcgtgg
     6001 tgatcacctc gaccatcggg tcgatgcaga tcttcgccga gccgctgctg ttcggcgcct
     6061 acaccctcac cggcggacag gaccggcagt accagacgct ctcgctgttc ttctacgaga
     6121 actacatgcg cctcgacttc ggcttctcct ctgccatctc ctggatgatc ttcgtcttca
     6181 tcctgatcat cgcagggatc aactacctgc tcaccaacag gatgaaggga agcatccgat
     6241 gaccggccgt cgggtcaaca accggctgac ctacctcacc ctgaccgcgg tcgcgttctt
     6301 cttcacgatc ccgctctact actcggtcgt ggtggcctcg cgcgacaacg cgtcgctggc
     6361 gtcggtgccg ccgccgctct tccccggcgg caacttcttc gagaacgtct cgcgggtctt
     6421 cgacaccgtg ccgttcggcc tggcgatgct caactcggtc ctggtggcgg gctcgatctc
     6481 gatctcggtc atgttcttct cgaccctggc cggcttcgcc ttcgccaaac tgcgcttccg
     6541 cggccgcaac atcctgctgc tcatgacggt cggcacgatg atggtgccga ccctggccgg
     6601 aatcatcccg ctctacatcc tcatggtgaa gctggagtgg gtcggttccc tgtacgccgt
     6661 cgtcgtgccc gccctggtca acgcgttcgg cgtgttcttc atgacgcagt tcctgtcccg
     6721 cgcgctgccg accgagctgc tggaggcggg ccgggtcgac ggctgcacga cctggggcct
     6781 ggtgtggcac gtcgtcttcc cggcggcccg cccggccgcc gccgtgctcg gcatgctcac
     6841 cttcatgacg gcctggaacg actacatgtg gccgctcatg gtgctcaccc cggagaaccc
     6901 gacggtccag gtggcgctct ccaccctcgc cgccggttac gtcaacgact acgtgatggg
     6961 cctcgcgggg accgccctcg gcaccctgcc gctggtcatc gtgttcgccc tgctcggcaa
     7021 gcacatcatc ggaggaatca tgcagggggc ggtcaaggga tgacgccgga catcgagttt
     7081 cccgaggggt tcatctgggg cgccgccacg gcgtcgtacc aggtggaggg ggccgcccgg
     7141 gaagacggcc gcggcgtgtc catctgggac accttcgcgc gcacccccgg caaggtcgcc
     7201 gacggccaca ccggagacgt ggcctgcgac cactaccacc gctatccgga ggacgtgcgt
     7261 ctcatggccg atctcggcct ggacgtctac cgcttctcca ccgcctggcc ccgggtcgtc
     7321 cccgacggct cgggcccggc caacccccgc ggcctcgact tctacgaccg cctggtcgac
     7381 gagctcctcg cggcggggat caccccgtac gtgaccctct accactggga cctgccccag
     7441 aacctggagg accgcggcgg ctggacctcc cgcgacaccg cctactactt cgccgactac
     7501 gcggcggccg tgcacgcccg gctctccgac cgggtctcca cctggacgac cctgaacgag
     7561 ccctgggtct cggcgttcct cggctacggc agcggcgtgc acgcccccgg cgtcaccgac
     7621 cccgccgcgg cgttcaaggc ggcccaccac ctgctgctcg cccacggcct ggccgcccag
     7681 aacctgaccg gcaccctggc cctgacgctg aacatggccc cggtcgtgac tccggcgcag
     7741 atcctggacg cggggatcgc gctgtcgggg gaggactccg ccgccgtgca cctggtggac
     7801 gccctgctca accggcagtt cctcgacccg gcgctgaagg ggacctaccc ggcggaggtc
     7861 ctggagatcg ccgaacgcca cggcggcctc gaccacatcc gcgacggcga cctggacatc
     7921 atctgccagc cgatcgacct gctcgggatc aactactaca acccgtgcgt cgtccaggcc
     7981 gccgccggag ccgtggcccc gacggcctgg ccgggcaccg acggcgtcga gttcgccgtc
     8041 atcgagggcc cgcagacctc catgggctgg cccatcatcc cgtcgggcct gtcccggctg
     8101 ctggtgcgcc tgtcgcgcga ctacccggac gtcggcctcc tcgtcaccga gaacggcgcc
     8161 gccttccacg acaaggtcgt cggcgaccgg gtgcccgaca gcgaccgggt ctcctacctc
     8221 gacggtcacc tgcgcgcctg ccacgaggcc atcgcggcgg gagccgatct gcgcggctac
     8281 ctcgtgtggt cccttttcga caatttcgag tgggcggagg ggtaccacca gcgattcggt
     8341 atcgttcgag tcgattacgc cactcagcgc cgcctgccca aggacagcgc cctgtggtat
     8401 cgcgacgtca tccagcggaa cggcatcgag tgaaacgtcc taccttggag gcggtcgccg
     8461 cccgcgccgg cgtgtccaag tcgaccgtct caagggtggt caacggcgac acgaccgtga
     8521 cgccgaactt ccgcgagctg gtgctgcggg cggtgaacga actgggctac gtgcccaact
     8581 cggtcgcccg cagcctggtg acccagcgga cgaactcgat cgccctggtg gtgtccgacc
     8641 cgcccgccgg cctgttctcc gacgacccca tgttctcggc cgtggtgcgt tcggcgtcgc
     8701 gggcgctgga ggcggcgtcc aagcaggtcg ttctgatgct ggccgggtcg gacgagagcc
     8761 gggtgcgcgt ccaggagtac gtcgccgccg gtcacgtcga cggcgtcatg ctcgtgtcct
     8821 tctacggcgc cgatccgctt ccagcggcgc tgatgcggat gggcctgccg atggcgtcct
     8881 tcggcaagcc cgtctcggcg ccctcggtcc cctacgtcga caacgacaac ctgggcgggg
     8941 cgcggcaggc cgtcgagcac ctgctggccc ggggacggcg gcggatcgcc accatctcgg
     9001 ggccgctcga catgatcgcg tcccaggacc ggctgaccgg gtatcgcgag acgctgcgcg
     9061 acacgggccg ccggtcgatc atcgcggtcg gcgacttcac cagggtgtcc ggggaccagg
     9121 cgatgtgcca gctcctggag gacgaccccg ggctcgacgc ggtcttcgcg gcgaacgacc
     9181 tgatggccat aggagcactg cacgccctga gacgggccgg ccggcgggtg ccggacgacg
     9241 tggccgtggt cgggttcgac gacatagagg ccgcgctcta caccgacccc ccgctgacca
     9301 cggtccgcag cccgatggcc gaccaggcgc tcgccgtggt cagcctgctg ctggggctgt
     9361 tcgaggacgg gcccgccgac ccggtgatac tgccgacgga actggtggtc cgggagtcgg
     9421 gctgatcagc ggcgcagcgc ccactccacg gccgggcagc ggttcatgac cacgtcgagc
     9481 ccggccgcca gcgcccggtc gccggcctcc tcgtcgtaga cgtcgagcgg cagccagacc
     9541 gcccccgccc cgatctcgac ggcctcgtcg atcatgccgc ccgcgaaggc ggtgcgccgg
     9601 tagatcgcga ccacctcgac ggggaccggt atctcggcga gggtccggta ggtcgtctcg
     9661 ccgaggacgg ggcgtccgtc cggatggacc ggaatgatct ttttgccgcg ttgcttcatg
     9721 agttgtgcct ggttgtagac ggtcctgccc ggatcgccgg acaaaccgac gaaagcccac
     9781 gtcgtcgtct cgttcagcag gcgccggatg accgtcaggt cggcgaaacg atctcccatg
     9841 tcttggtgca acaacgtgat cgtcggctct cttccggcac aggtcaggcc gggtattcac
     9901 gacggcaccc gtgacgtttg cccacagagg attgattgaa cttgtaacta gaagctcttg
     9961 gggttatccg caattcttcc tgttagcaga aagcagggag atggcagtga atgaccaata
    10021 tgagctttat tgcctcgcgg accggctttt ctatgacacc cccgaccggc gcggaaccga
    10081 aattcccgat ttcgccgtgg ccgggcgtga cgttccgcgt ggctggtccc accagccgtc
    10141 cgacacctgg ttccactacg ccccgaccgg ccacgatgtt ccgccgcagg gctggaagat
    10201 ccatgtgtcg gccgggctgg ccgacgcggc gcgggtgctg gaaatcgtct gggactattg
    10261 cgtcgagcgt gatattccct tcaaattcct gcgcagccgg tccgttgtca ccatgctcaa
    10321 ctcaaaaggt gcctcgcggg gcgcgagcgg caaactggtc accatctacc cgcgccagga
    10381 ctgtctcgaa ctgacgctca aggagctcga cggcctgctg gcgggggtac gggggccgta
    10441 catcctgagt gatctccgct acggcgacgg gccccttttc gtgcgctacg gaggattcgt
    10501 ggcccggcgc tgcgccgccc ccaacgggga gctcgtgccg gcgatggaga acgaccgggg
    10561 cgagctggtg cccgacgagc gggggccctc gttcacgatc ccgccgtggg tgacgctgcc
    10621 cgacttcctc cacgcccatc tcgaggccag gaacgcggtc accacgaccg agctgcccta
    10681 cgcggtcgac tccgtcatgc acttctccaa cgggggcggg gtctacctgg ccaccgaccg
    10741 gcggaccggc gagcgggtcg tcctcaagga ggcccggccg atggcggggc tcgacgcgtc
    10801 cgagcgtgac gcggtggcac ggctccaaca cgagcgcgac gtgctgcgac ggctcgacgg
    10861 gctcgactgc gcgcccggct accgcgacta cttcgtgctc ggcgaccacc acttcctggt
    10921 gatggagttc gtcgacgcca cgccgctgca gcgcacgctg gtccgcacgt tcccgctgac
    10981 cagggccgac gcctcggccg ggtcgatcgc cgaatacacc gtctgggcgc tcgacacgct
    11041 gccaaaggtc caggccgccg tcgcggcgct ccacgaacgg ggcgtcgtct tctgcgacct
    11101 ccatccgaac aacatcctga tcacgcccga cgggcggctc gtcctcatcg acttcgaggt
    11161 ggcgacgttc gccgaggacc tcggccggtc ggtgctggcc catccggcct tccaggcgcc
    11221 cgccgaccgg cggggcaccg acgtcgacca ctacgccctg gcctgtctca cgctgggcct
    11281 gttcgcgccg cagctcacga tcaccgtgcc gctggcgcgg gccaaggcgg cccagctcgg
    11341 gcagatgatc gtcgacacct tcccggtgcc ggccgagctg atcaaacggg ccgtccacac
    11401 gatcaccggg gccctcgggg gcgggcccac ggtgagcgtg accagcggcg atccgatgac
    11461 ggcgatggcg cgggcgatcc tggccagcgc caccccccac cgcgccgacc ggctgttccc
    11521 cggcgacgtc gcccagttcc ggcccggcgg cgggatcaac atggcccacg gcgcggccgg
    11581 ggtgctgttc gcgctcgacg cgtcgggggc cggacggttc cccgaccacg aagagtggct
    11641 cctgcgccag cagggcgagg ccccgcccgg cttctacgac gggctccacg gcgtcgccta
    11701 cgtcctcgac cggttcgggc acgtcgacag ggcgctcgac ctcgtcgacc gggccatggc
    11761 cggcccgtgg cgcgatctcg acctcagcct ctggtcgggg ctgcccggca tcgggctcaa
    11821 cctgctccac ctggggctcg acgcccagcc gctggtcgaa ctctgcgccg accggctgcc
    11881 cgccgacgtg ccggagatct ccggcggcgc caaccccaga gccggtcttc tccacggcct
    11941 gagcggcccc gccctcctct tcctgcgcgc ctacgaccac acccgcgacc ccgccctgct
    12001 cgacctggcc gaacacgcgc tgcgcctcga cctgaaacgg tgcacgacca ccgccgacgg
    12061 atcgctgcag gtcgaccagg gctggcggac gctgccctac ctcgacgagg ggtcggtcgg
    12121 catcgcgatc gcgctggccg acctgctccg ccaccggccc gggtcacccc tggccgccgc
    12181 gctgcccgac ctggtgaaag tgggccgctg ccgcttcttc gtgcagcccg gcctgttctc
    12241 cgggcgggcc ggcatgatcc tggccgaccg gacgctgatc cccggcctcg actggcacat
    12301 ccttccctac cgcgacggga tcgccttccc cggcgaccag ctgctccggc tgtcgatgga
    12361 cttcgcgacc ggcaccgccg gcgtcctcta cgccctcagc ggcaacccgt tgcccttcac
    12421 acatccactc ggcgcggagc cccacgccgt gcccggtggc gcccccccgc acccaccggc
    12481 caaggaggtg atcggggccc cgaacagcta gctccacctt tctaagatct cgaattcctc
    12541 ccgatagaca tctcacaaag gagcatgacc atggttcttc tcgaccttca ggcgatggag
    12601 cttcccggcg gcggtcaccc cggtggcggc ggtcacggcg gcggcggcag cacgctgacc
    12661 ctgctcggct gcgcgtccca gacgcccagc aacctgagcc tgctgctctg ccactaggca
    12721 cccgatcggg gccctgggct cgcgggagct cagggccctc ccttgttcat gcgcagttgt
    12781 tcgttcagtt ctcgcccacg tgaagagagg gacccggcgt tgcggacggc cgatcggctg
    12841 acagccgagg cgatcaggcg gagcgggccc gcggcgggcg tgctcgccgc tgtcgcgctg
    12901 gccggcgccg gccttgagct ggcgctgccg ttcgtgctcg gccgcgccgt cgacaccttc
    12961 tctccctcct gggtggcgtt ggccggggcc gtcgtggtgc tcctcgtcgc ctgcgacggt
    13021 ctcggcgtct acgcgagcgg gaccggtggc gcgcgggcgg cggcctggct gcgtcaccgg
    13081 acgctcaccc atctgctggg cgtcggcccc ggggtgaccc ggcggatccc cgagggcgac
    13141 ctggtcaccc ggctcggcgt caacgccgag gaggcggggc gggccggtga cgcgatggtc
    13201 gcgtcggtgg cgctcgtggt gccgtcggcc ggggcgctcg tgctgctggt gctgatcgat
    13261 ccgtggctgg cgctgacgct ggcgggcggg ctggtcgtga tcgccttcgt gctgaagcgg
    13321 tttctgaaga cgtccacggt gatcgccggg ggctaccagg aggcgcaggc cgacatcgcg
    13381 tcccggctgg tcgaggcggt cgccggggcc cgcaccatcg ccgccgccgg gaccgccgag
    13441 cgggagacct cgcgggtgct gaccgcgctg ccggtggtcc ggggccacgc gatggcgctg
    13501 tggcgggcca acgccgacgc gggggcgcgg gccgcgatcg tggtgccgct gcttgaggtg
    13561 ctggtgctgg ccgtaggcgg ctggcggctg tcggccgggg aactctcggt cggcgagctc
    13621 tacgccgccg cccgctatgt ggtcatcggc gcgggcctgg ggcccgcgat cggatcactc
    13681 gggcggctgg cccgcgcccg cgcggccggc gcgcggctgg cggagatcct cgacgagtgc
    13741 ccccggaccc acggggtgcg gacgctgccc gccggacccg gaagactgac cttccacgac
    13801 gtccccggcc tcgcactgga gatcccgggc ggcgcctcgg tggccgtggt cggcgccggg
    13861 gccgcccggt tcgcgcgtct cgcggcgcgc ctcgacgacc cggagagcgg tgaggtcctg
    13921 ctcgacggcg tgcccctgcg gtcgctgacc cgcgcgtcgc tccgcgccgc cgtcggctat
    13981 gccgtcgccc ggccccatct ggtcggcgac accgtcgccg acgcgatcgg cggctcccgt
    14041 cccgcggccg tggccgccgg ggccgacgac ttcgtccgcc gcctgcccca cggctaccag
    14101 accgccctcg ccgaggcccc cctgtcgggc ggcgaacgcc agcggctcgg cctggccagg
    14161 gcgttcgcga agggcaaccg gctgctggtg ctcgacgacg ccacatccag cctcgacacc
    14221 atcaccgagc ggcaggtctc caacgccctg tccgccgacg cccgcacccg cgtcacggtg
    14281 acccaccggg ccgccgtcgc cgcgcgggcc gaccgggtgg tctggctcca cgacgggcgg
    14341 ctgcgcggct tcgaccgcca tctcgcgctg tggcacgacc cggcctaccg ggccgtcttc
    14401 caggggggcg cgtgacctcc ttcggacgcc ggacccgggt cgggccgttc ctctggcggt
    14461 cgttccacgc ccagccgggg caggcgcggc ggttcgtcct ctggtcgctg gtcgaggccg
    14521 ccccggcgtt cgtcatcggg ctggccatcg cgcgggcggt cgacgcgttc accgcgcagc
    14581 gggccgtcgc cgggctctcc tggacgctgc tgctcggggt ctcctgggtc ttcgccgccg
    14641 tcggggcgcg gcaggtggtc gtcacgctgg cgaccatcgt cgagcccgtg cgggaggggc
    14701 tgctgacggc gaccgtgcgc ggggcgctgg agtcgggcaa ggacgacccc gccgccgtga
    14761 ccagggccaa cctccaggtc gaggtggccc gcgacgcctt caccggggtc atcgggtcgg
    14821 tcaaggcgtt cgtgttcgcc cttctcgggg tcgtcgccgg ggtggcggcg ctgatgccgg
    14881 agctgctcct gctggtgctg ccgccgctgc tgctcgggct cggcgcgttc ctcttctcgc
    14941 tgccggagct ggccaggcgg cagcacggct atctgctcgc cgacgaggcc accgccgaga
    15001 gcctggtcag ggtcaccgcc gcgctcggcg acgtcgccgc gtccggtgag gaggagcacg
    15061 ccgcccgcta cgccggcgcc cgcttcgacg gccagcgacg ggcggcgcgc aggctggccg
    15121 gggtgaccac gctccgcacc gtcgtgctgg gggcgggggc gtgggcgccg atcctgctcg
    15181 tgctggccta cgggccgcgc ctgggcgcga cccccggtgt cgtgctcggg acgctggcct
    15241 acgtgatgca gtcactcacg cccgcgctgt tcaacctggc cagcgggctg ggggagagcg
    15301 gggtgcggct ctgggtcacg ctgacccggc tgcgggccgc cctgccacca ccggcgcagg
    15361 agacccgccg ggccgagggg gtgcacaccg agctgaaggg ggtcacgttc gcctacgggc
    15421 cccaggcgct gccggtcgtc gaccacctcg acctggtcat cgccgaaggg gagcacctcg
    15481 cggtcgtcgg gccgagcggg atcggcaagt ccaccctcgc cgccctgatc gccgggatgg
    15541 tcgcgcccgg tcagggcagg gtgatcgtcg gcggggtccc ggccgcgcgg gtcgacaggg
    15601 gacagcgggc gctgatcccg caggaggcct acgtcttccg ggggaccgtc gccgagaacc
    15661 tgggcgacca cgagccgcga cggatgcggg aggccctcga cgccctcggc gcggggcaca
    15721 tcaggcttca gtcggcggcc accgagctcg gaccgtccga ccggcagctc gtcgcgctgg
    15781 ccagggccta cctcgccgac gccccgctgg tcatcctcga cgaggccacg tcgtgcctcg
    15841 acccggcggc cgaggcgctc gtcgagcagg cgttcgcggc gcgcggcggc accctgatcg
    15901 tcgtcgccca ccgcgtcagc tcggccctcc gggcccggaa tgtgctggtc atggacggca
    15961 cccgcgtcgt caccggcacc catcaggaac ttctcgccgc ctcgccgctc tacgcggatc
    16021 tggccgggca ctgggacccc cgactcaggc aggtttcatg atcgacatca ttcacggaca
    16081 cgtcgtcgcg gacccctacc gctggctcga agaccccggc tccgacgaga cccgggcctg
    16141 gcaggcgcag caggaggccg tctggcagag ccagctcctg cccgagcggg acaggttccg
    16201 ggccaggatc gacgagctga gcgacaccgg cgtcgtgggg gccccgatct ggcgcgccgg
    16261 caccgccttc cgggtccgcc gcgacccggg ccgccgcctg cccgtcctct acgccgatga
    16321 ccggccgatc ctcgaccccg aggcgatcga ccccggcgcg accaccctgc tggaggcctg
    16381 gcacccctca cccgacggca cgctcgtcgc ctgccagctc tcccggggcg gcgacgaacg
    16441 ctccgagctc tacgtcatcg acgcccggac cgggggcctc gtcggcggcc cggtcggggg
    16501 gctgcgccgc tcgccggtgg cctggctgcc gggtggcgac ggcttctact acgtccgcga
    16561 ccgccgggcc cgcctccacc gcctcggcgg cgacgacctc gacgtggccg acgccgacgg
    16621 cctggccctc agcgccgacg gccgctggct caccctgtcg gtcaaccggg ggccgggcaa
    16681 cgacgtgtgg ctgtgcgacc tggtcagccc ggccaggcgg gtcgtccagc aggacgtcgc
    16741 ggccaggtcg gcggtcgcgg tggggggcga cgggagggcg tacatgatca cgaccctcga
    16801 cgccccccgg ggacgcctgc gcgtggccga ccccgccgcg ccccacgact tccgcgacct
    16861 ggtcccggag gacgccgaag cggtgatcgc cgacttcgcc ctgctcgacg gggttctcct
    16921 ggtggcgtgg gtgcgccacg cgatcggaga gatctccgtc cacgatcccg agaccgggga
    16981 gcgtcaagga gcggtcccgc tccccggtct cggctccatc gggcggatgt ccgcccgcga
    17041 ccacgaggtg tggttcacct actccgacta cgtcaccccc gagagcgtct accgctacga
    17101 cgcccgaacc ggcgagacca ccctgtggga ggccgccccg ggccgggccg agctgcccga
    17161 gatcgagtcc caccaggtcg tctaccagtc ggccgacggc accccggtcc ggatggtcgt
    17221 gctcagccgg gggctgccgg ggccgagccc gtgcgtcctc tacggctacg gcgggttcgg
    17281 ggtgccgctc accccctcct actcctccta cgtcctgccc tggctggagg cgggtggcgt
    17341 cttcgcgttc gcccaggtca gagggggcgg agaagagggt gaggggtggc accgggccgg
    17401 gatgcggggg cgcaagcaga actcgttcga cgacttcgcc gccgccgccg agaccctgat
    17461 cgcggcgggc tggacccggc ccgacctgct cggggtcacc ggcgagtcgg gcggcgggct
    17521 gctcgtcggg gcgctcgtca cccagcggcc ggaactggtg gccgccgccg tctgctccgc
    17581 gccggtgctc gacatgatca ggttcgaacg gtcggggctc ggggcctcgt gggtgccgga
    17641 atacggctcc gccgacgacc ccgagcagtt cgcctggctg ctggcctact cgccctacca
    17701 ccacgtcaag gagggggtcg actacccggc caccctgttc accgtcttcg acggcgacag
    17761 ccgggtcgac ccgctccacg cccgcaagat gtgcgccgcc ctccaggggg cgacctccgg
    17821 cgtgcggccg atcctgttcc gccacgaggc cggcgtcggc cacgcgggcc gatcggccga
    17881 ccgcgcggcc gggctggccg ccgacatgct ggcgttcctg gcccgtgagc tgggcctcga
    17941 ccagggttag ggagccgtca ggccgaccgc tgcaggagca gggccatcgc ggcgggcggg
    18001 gcggtggtca gggacatctc gaaccagacc ttgttgcggc cgccctcgcg gacgatgccc
    18061 caccggtcgg ccagggcgtc gagcagcggc aggccccggc cgttggtggc ggtcgcggtc
    18121 gagtggccgg cacacggcgg ttcggccgag ccgtcgtcct ggacgcagac ccgcacctcg
    18181 tcggaggaga accagaccgt cacggtgaac acgccgccgt cgccggatct ggagtggacg
    18241 accgcgttcg tggcgatctc actcgtgagc agcacgcagt cgtcgtggag cgggtggtcc
    18301 ctgccgatcg tggccgagac gagccgccgg gccaggacga tctggtcgcg gccccccgcg
    18361 agccgggcga ccctggcggc ccggagatcg gtggtgatag tcgtgtcgat ggagtcgagt
    18421 gtggtgacgt tccccgaacc gttcatgcgt cctcctcgat gactgcgcaa tgaagacgcg
    18481 ccaccacggc gtccgagatg tcacgcgaag gtgcgactgt gcttccctga gggaaccggc
    18541 gctgccgtag tgtcgggacc atgctgacgc tgatggcggt gcacgcccac cccgacgacg
    18601 aggtcatggg caccgggggc atcttcgcga aatacgccgc cgaaggggtg cgtaccgtcc
    18661 tggtgacctg caccaacggc gaccagggcg acgggccggg cggggtgaag ccggggcagc
    18721 cgggccactc cgaggccgac gtggtcaaac agcggctggc cgagctggcc gagtcggtgg
    18781 gccacctgaa catcggccac gtcgagctgc tcggataccg cgactcgggc atggacggct
    18841 gggacggcaa cgccagcccc gacgcgttcg ccaacgtcga cttcgaccag gcggtggcca
    18901 aggtggcggc gctgatggcc gaatatcggc cggaggtcgt cgtgacgtat gacgagaacg
    18961 gcaactacgg ccatccggat cacatccagg cccaccgggt ggcggtggcg gcgagcgacg
    19021 cgaccgggat tccggtgaag ttctactaca cggcggtgcc ccggggggtc atccaggcgt
    19081 cggtcgcggc gatgaaggag cagggcatgg acccggggtg ggaggtgccc gacgacttcg
    19141 gcacccccga cgaactgatc accacggtgg tcgacaccca cgagcaggcc gaggcgaagg
    19201 tcgccgccct gcgggcccac gccagccagg gcgacagcat cgccctgctg tcgatgccgc
    19261 cggagatgca gcggatggcc atgtcgaccg aacacttcgt ccgggtcttc accaaggtcc
    19321 ccgcccccga ccgcgaggac gacctcttcg ccggcctgcg ctgacgccgt cacggcgctc
    19381 ggacgagcgg ccggtgagcg ccgggccgac cggccgtcgc cggggcggcg ggcggggtgg
    19441 gggtaggcgg agccgtaacg gaagcgagcg gttctccagc agcgggcccg gcgcttctca
    19501 gcgggcccgg cgttcgtaga gggccttctc ctgggcgttg cgggtgaggt cggccgcctg
    19561 ccggaaggcc gctctggcct cctcggcgcg gccgctgcgt tcgaggaggt cgccgcgcac
    19621 tgcggccagg tgggggttgc cttcgagttt caggttgtcg acgatcttga ggcctgcctc
    19681 cggaccctcg gccaggccga ccgccacggc gcggttgagt tcgacgatcg gcgacggcgc
    19741 gacgtgggcg agcagctggt agagggcggc catccgggcc cagtcggtgt cggcgaaggt
    19801 cagggccctg gcgtggacgg ccgcgatggc ggcctggagg ccgtaggggc cgagggtgcc
    19861 ggtcgactcg gcgcgggcca gcgccgaaag gccccggcgg atcagcaggc ggtcccaggt
    19921 ggtgcggtcc tggtcgggga gcaggaccgg ctcaccgccg gggccgacgc gggcggccag
    19981 ccgggacgac tggatctcca gcagcgcctg aagacccagc gcctcggagg aggagggcat
    20041 cagcgcggcc agcacgcggg acagccgcag cgcctcgaag cacaggtcgt tgcgggtcca
    20101 cgagtcgccg gccgtcgccg cgtagccctc gttgaagatc aggtagatga cctccaggac
    20161 cgaggccagc cgcgcgggca gctcctcggc gggcgggagc tcgatcggga ccttccgcag
    20221 cgccgtcttg gcccggtaga tccgctggcc gacggtcggc tccggcacca ggaacgcccg
    20281 cgcgatctcc gccgtcgtca ggccgcccag cagccgcagc gtcagcgcca gccgcccttc
    20341 gacggccacg tcgggatggc aggccgtgaa gatcagcgtg agcagctcgg gttccgggga
    20401 cggctcgggc agcagggcga gttcgcggag tttctcctcg tagacgccct gccgccggag
    20461 ctggtcgatc gctttgcgct tggccgtggt ggtcagccag ccgcccgggt tgtccgggac
    20521 gccgtcacgg ggccaggcct ccagggccag cacgaacgcg tcctgggccg actcctcggc
    20581 caggccgatg tccccggtca tcctggccac ggtcgcgatg accttggccg attcgatgcg
    20641 ccagacggct tctatcgtgc ggatcggatc ggcaggcccc atgtcctcag aatgtcatca
    20701 gcgggtagac gtgggacacg ccctcccagc ccggccacat gtcgcggtgg agcttcatga
    20761 agcggttggc ccactcgacc gcctcggccg cgtcgcggac ctcgtagatc gcgtagctga
    20821 tcagttcctt ggcctcggcg aacgggccgt cggtcacggt cagtttgccg ccgacgacct
    20881 cgacctgacc ggccatggcc gaaaggccgc tctggtcgac gaggacgccc gactcggtgg
    20941 cctcccggcc gagctgcatg atcgccgcca tcagttcggc gggcggcggg gtctcgggct
    21001 gggcggtgcg ggtcagcgtg atcaggtagc gcatgggtgt tctccgttcg ttctcctgtg
    21061 aacctacgac ccctccacga acggccggcc ggagtttcga cggccaccgg ttactttttt
    21121 tggatttccg gccatgctgg tgaggtgagc agcaggcctc cctatccggg gctggcagcg
    21181 ttcggggccc aggacgccgc cgtgttcttc ggccgtgacg acctcctgtc ccacctgcgg
    21241 cggcgtgccg ggagcgagcg gctgctcgtg gtcacgggag cctccggggc ggggaagacc
    21301 tcgctcgtcg acgtcggcct cgcgggcggg ctgaggctgc ggccgggcgc cgatccggtc
    21361 ggcgcgctgc tggccgcgtt cggggccggg atggaccacg aacggctggc cgccgcgccc
    21421 caccacctcg acgagctcgg cgatccgggg ctgatcgtgg tcgaccggtt cgaggaggtc
    21481 ttcgcggcct gccgcgatct caccgcccgg cagaccttcg tcggcgcgct caccgccacc
    21541 cgcacccccg tggtgctggt gctgcgggcc gacttcaccg gcgacgccgc cgcgttcccc
    21601 gagctggtcg cggccctttc ccggccgctg ctcgtctcgc ccctgtctcc ggacgacctg
    21661 cgcgccgccg tcgagcagcc cgccctggcc catggggtga ccttcgccga cggcctggtg
    21721 gaggagatcc tcgccgacca caacggcgac ctgccgctgc tggcccacac gctgcgggtg
    21781 atgtgggacc ggcgcgaggg cgacgtcctg acgttggaca cctaccgggc caccggccgg
    21841 gtgaccggcg cgatcccccg cagcgccgaa cgcgcgctgg tccggggcga cgccagggct
    21901 gcgctgtcgg cgctcgccgg gccccacggc accctccggc ccggcccgat ggtcccggag
    21961 ctcgaacctt tcgtggccgc cgggctggtc agccgcgacg gggagacggc cgaactggcg
    22021 cacgaggcgg tgatccgggc ctggccccgg ttcaccgcgt ggaccgaggc cgatcgggcg
    22081 gccggtcagg tgcgcaggga gttccaggcc gacgcgaacc gctgggtgct gagcgggttc
    22141 gccgcgcccc acctctacca gggctcccgg ctcgcggcgg cccgcgccgc ggtgcggcgg
    22201 atcaggcggg agctgtcccc ggccgaggtg gcgttcctcg aggcgagcgc ggcccaggcg
    22261 atggaggggc ggcgggcggc ggagagacgt accttcctgc ggggtctgtc gctggtcgcc
    22321 ctgatcgcgc tgctcgtcgt gagcttcggc gcgaccggcg cgctggcgct gctgatcacc
    22381 ggggccaccc gcgaccggga cgccgcggtc gaccggagca ccaccgccgt ggcccgccac
    22441 ctgctcgccc agggcgacgc gctcgccgcc gaccagccgg tcctcgcccg gctgctgcgg
    22501 ctcgcggggg c
//
