LOCUS       NZ_BBXD01000027        22154 bp    DNA     linear   CON 08-AUG-2024
DEFINITION  Herbidospora mongoliensis strain NBRC 105882, whole genome shotgun
            sequence.
ACCESSION   NZ_BBXD01000027
VERSION     NZ_BBXD01000027.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Herbidospora mongoliensis
  ORGANISM  Herbidospora mongoliensis
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Herbidospora.
REFERENCE   1
  AUTHORS   Komaki,H., Ichikawa,N., Oguchi,A., Hamada,M., Tamura,T. and
            Fujita,N.
  TITLE     Genome-based analysis of non-ribosomal peptide synthetase and type-I
            polyketide synthase gene clusters in all type strains of the genus
            Herbidospora
  JOURNAL   BMC Res Notes 8, 548 (2015)
   PUBMED   26452464
  REMARK    DOI:10.1186/s13104-015-1526-9 Publication Status: Online-Only
REFERENCE   2  (bases 1 to 123250)
  AUTHORS   Hosoyama,A., Oguchi,A., Ichikawa,N., Kimura,A., Ohshita,R. and
            Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-MAY-2015) Contact:Director-General Department Of
            Biotechnology National Institute of Technology and Evaluation,
            Biological Resource Center (NBRC); 2-49-10 Nishihara, Shibuya-ku,
            Tokyo 151-0066, Japan URL :http://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Noncontiguous Finished
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: newbler v. 2.6
            Genome Coverage                   :: 62x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001570545.1-RS_2024_08_08
            Annotation Date                   :: 08/08/2024 02:40:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,280
            CDSs (total)                      :: 8,202
            Genes (coding)                    :: 8,113
            CDSs (with protein)               :: 8,113
            Genes (RNA)                       :: 78
            rRNAs                             :: 4, 6, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 4, 5 (5S, 16S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 21 of 89
            Pseudo Genes (incomplete)         :: 71 of 89
            Pseudo Genes (internal stop)      :: 4 of 89
            Pseudo Genes (multiple problems)  :: 7 of 89
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:23:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 89386
            Orig. end                         :: 111540
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBXD01000027.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22154
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22154
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22154
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12154](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12154)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(102..116)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 24.85"
                     /tool="antismash"
     gene            198..893
                     /locus_tag="AW272_RS37255"
     CDS             198..893
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW272_RS37255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_083959098.1"
                     /transl_table=11
                     /translation="MEDQIVIGARFNGPPTSANGGYVSGLAAAFVDGPARVLLRTPPPL
                     ETPLDVTRDGDTVRVTHDGVLVVEAGPSSAVFLDPPVRPTFGEASAARDRHPWIGADNL
                     LTGCFVCGHGRADGLRVTPGRLADADVCASPFEPDETVAGDGIVRPEIVWAALDCVSYP
                     PFAQGTDTIALLGTFEAEIARSVAAGERLVAVGWPLESSGRKLFSASALLDGDEVVARA
                     RATWITLPG"
     misc_feature    complement(202..217)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.49"
                     /tool="antismash"
     gene            918..1571
                     /locus_tag="AW272_RS37260"
     CDS             918..1571
                     /NRPS_PKS="Domain: Abhydrolase_1 (17-120). E-value:
                     3.4e-27. Score: 87.5. Matches aSDomain:
                     nrpspksdomains_AW272_RS37260_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="AW272_RS37260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_066375116.1"
                     /sec_met_domain="PF00561 (E-value: 9.4e-24, bitscore: 77.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.3e-20, bitscore:
                     67.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVVPLAWKEGGTPGDIPVVLIHGLTGSSATWDRIAPALGRHWIA
                     PDMRGHGASPRHPDYSLELMAADTLAFLDARGLTRIDLVGHSMGGRVAALVARDRPGLV
                     RRLVLEDSFPAAHEPQVIEPYEVIGDEDFDPAVVDVIRTDVRRVDPTWWARLPELTMPV
                     LVVGGGLSELVPQEALVEFAEALPDGRRVVLKAGHSVHKEEPDGYVKEVAAFLR"
     aSDomain        969..1277
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AW272_RS37260_Abhydrolase_1.1"
                     /evalue="3.40E-27"
                     /label="AW272_RS37260_Abhydrolase_1.1"
                     /locus_tag="AW272_RS37260"
                     /protein_end="120"
                     /protein_start="17"
                     /score="87.5"
                     /tool="antismash"
                     /translation="PVVLIHGLTGSSATWDRIAPALGRHWIAPDMRGHGASPRHPDYSL
                     ELMAADTLAFLDARGLTRIDLVGHSMGGRVAALVARDRPGLVRRLVLEDSFPAAHEPQ"
     CDS_motif       1164..1211
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AW272_RS37260_0001"
                     /evalue="1.90E-05"
                     /label="NRPS-te1"
                     /locus_tag="AW272_RS37260"
                     /protein_end="98"
                     /protein_start="82"
                     /score="17.2"
                     /tool="antismash"
                     /translation="LVGHSMGGRVAALVAR"
     CDS_motif       1401..1496
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AW272_RS37260_0002"
                     /evalue="5.90E+00"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="AW272_RS37260"
                     /protein_end="193"
                     /protein_start="161"
                     /score="0.2"
                     /tool="antismash"
                     /translation="PVLVVGGGLSELVPQEALVEFAEALPDGRRVV"
     gene            1594..2628
                     /locus_tag="AW272_RS37265"
     CDS             1594..2628
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW272_RS37265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="macro domain-containing protein"
                     /protein_id="WP_066375118.1"
                     /transl_table=11
                     /translation="MDVPEHEDLVRDLLTLRERGLIRLRDADLPHLRRAAALCHPATDP
                     VAAVEKTLRDAVGRLGEGTLGSGAAYTFGLVQGTRDWSAAARRKRAADVYRLSVERFRK
                     NQERMLLAQVADQIIALCGAGGEAALPRIAVGARIPVESDGGRAILQIRPIELISGVDV
                     LVNPENVYLEMARVFSPSVSGAIRKAGSRRGPAGELLDDTVQRELHEWMAKHHRPGLTV
                     APGTVAPTGPGSLAFNGVRRVYHAAVAVPRPGTDHQDVTPSTIMLAVHRVFALAEEERV
                     AYRLKTICFPLLGTGHGRLAVRPGLHWLWSAISENLARSRGWEVHLSVPEPEKADIVLR
                     QLSP"
     misc_feature    1663..1665
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(2573..3544)
                     /locus_tag="AW272_RS37270"
     CDS             complement(2573..3544)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW272_RS37270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_066375120.1"
                     /transl_table=11
                     /translation="MVAVTLTRSASGMWAWAAGRALAARDVPASGAEHAAWTVRGWAEI
                     ALGCALLGPAAFDGLDTVILATRIRRGGPAADRLRALRGRAGPVPRGYPSSDDPGPVDG
                     PGEETREACRALAAWCATIPDRDGPVRPVRDHLRWGERHRPAATRDVTILDGSRFTGLA
                     WRTWMRLPGERGLITVLVDHTHRAPELRRRVWRGIHDGAHLDHLAACGEDIEFGRGLLA
                     AETYAMAVELVALAETRDAAVRRILKHGVLERIARIPGNGADNPELQRLPTLAATYVTG
                     ALRLLGGGAEGVPARLREPLRARWVRATAGAARCRPSLVPAR"
     gene            complement(3532..4221)
                     /locus_tag="AW272_RS37275"
     CDS             complement(3532..4221)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (5-224). E-value: 1.2e-22. Score:
                     72.9. Matches aSDomain:
                     nrpspksdomains_AW272_RS37275_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014698.4"
                     /locus_tag="AW272_RS37275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_066375121.1"
                     /sec_met_domain="TauD (E-value: 2.2e-22, bitscore: 72.9,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVTEMTEAEDRLATRGWVVVRGSWDVPTHAQALRFAARFGRPSS
                     RDGGRPVWEVRPRPLGGTFSQRSGPVPLHTDAQYHPDPEDVVCLFAVRPAVDGGHSLLL
                     SADQALTALRRHPEGARAEAALRRPQWSWTTPAVFSENPGRSSPPAPVFAGETLRWRPD
                     NLVPVPESSWRAAASVFTDVLVRVEPVEVRLAPGDVLLVDNHRTLHGRTSFADLQRLMF
                     RIRLWSR"
     aSDomain        complement(3550..4206)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AW272_RS37275_TauD.1"
                     /evalue="1.20E-22"
                     /label="AW272_RS37275_TauD.1"
                     /locus_tag="AW272_RS37275"
                     /protein_end="224"
                     /protein_start="5"
                     /score="72.9"
                     /tool="antismash"
                     /translation="MTEAEDRLATRGWVVVRGSWDVPTHAQALRFAARFGRPSSRDGGR
                     PVWEVRPRPLGGTFSQRSGPVPLHTDAQYHPDPEDVVCLFAVRPAVDGGHSLLLSADQA
                     LTALRRHPEGARAEAALRRPQWSWTTPAVFSENPGRSSPPAPVFAGETLRWRPDNLVPV
                     PESSWRAAASVFTDVLVRVEPVEVRLAPGDVLLVDNHRTLHGRTSFADLQRLMFRI"
     misc_feature    complement(4352..4370)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.44"
                     /tool="antismash"
     misc_feature    4370..4385
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.01"
                     /tool="antismash"
     misc_feature    complement(4370..4388)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.98"
                     /tool="antismash"
     gene            4391..6499
                     /locus_tag="AW272_RS37280"
     CDS             4391..6499
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW272_RS37280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157519216.1"
                     /transl_table=11
                     /translation="MSSYRGNQAVLAQERRLAAIAAASAAAFRHSDYHQVRAEDVAERV
                     RLPRGGEKDTGRSAVWLYNEVRSRRVLVALAAKHAFDEFTTGESPSEPVTSMLGAAESV
                     AAALRRIARFHQVERFLLAQVRLGIGDISTSEKRPSAAQTPPVWLTGTYGSAAAAGWEG
                     RVTAYAEYLAPRLDQAARAVAVPTESWAKESAERLSELAFRAMSDDPDAPADRQAEGLA
                     AYWLARDLIPLTGEWADRLHAAERTAELVEKIGPNGRSRANALVVVFQVLLDSSPLLVR
                     AAEVGADLVPLLTGSPADGLTLCDVTSRRGLALLRLGDTAGARACFEESRRIAEKLPDS
                     ADPASLIARAEHNLAELLVDEGKPERGRAILADVAARRGNGVPQAGAGPEWRRHTLTRQ
                     ALARATTKAGRIVEGVSLAESTLADREDRLGPDNVNTASARVTLAEALLAAAHPAQARH
                     HLTEAMRLRSLYLPSEGFWPQYDLVRLAEIELHAGFPAQTVRLLDEATVTTTWFAERVS
                     PRLHEESVLVRSLGMIHSGEALTALNDLAELTQTRAVLRAQAEARLTVGDPASAARLLD
                     DIEGDGSVTDRAETLLLSARVSSALGREAAAEEACQSVVAMGGDQIDATHPTVLGARLG
                     LALQRVRSDRAAEVGDLLAPLLDRRALPHGKPALGDGHPLLAEAMALAARAGSPPTRAP
                     EDQLWENF"
     misc_feature    6500..6513
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
     gene            6850..7584
                     /locus_tag="AW272_RS37285"
     CDS             6850..7584
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017589623.1"
                     /locus_tag="AW272_RS37285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_174551889.1"
                     /transl_table=11
                     /translation="MESSSLIALTPALPLALVLLVAGGAGVAAAGGLGYGWAVVRACLR
                     GVLQLGVVSLIIAWVVANGLAVAGFILVMYAFATHTAAKRIGTYWAALPVAAGSAPVLG
                     VLTATGAVTLDGMVIIPVTGIVFGGCLIATSLAGRRAADELTTRHGEVEAAMSLGFTPR
                     DARLEICRPAAAQALVPALDQTRTVGLVTLPGAFVGMLIGGATPVEAGIVQLVVLVALL
                     SAEAFAVVLTIELAARGRLIRP"
     gene            7668..7973
                     /locus_tag="AW272_RS37290"
     CDS             7668..7973
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893942.1"
                     /locus_tag="AW272_RS37290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_066375127.1"
                     /transl_table=11
                     /translation="MIKKLHNMGLRSSHMYTAAMASIGLSFCTWVVSRQMESAGIDRAD
                     RWGIFIGQWAPTLMAMGVALRVEETHMTDDEMRKMDSDMEMGTRTSGNSRVHAPAR"
     gene            complement(8060..9022)
                     /locus_tag="AW272_RS37295"
     CDS             complement(8060..9022)
                     /EC_number="2.7.7.-"
                     /GO_process="GO:0009190 - cyclic nucleotide biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0035556 - intracellular signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546873.1"
                     /locus_tag="AW272_RS37295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenylate/guanylate cyclase domain-containing
                     protein"
                     /protein_id="WP_066375130.1"
                     /transl_table=11
                     /translation="MSIDDPRVDGLTEAFLRQPRRYTSHQVAQMAGVPFHRARRFWRAL
                     GFANVADDAIEFTDADVEALRTLMALLADGTYDDEHIMLMARSLGRASARLAESQAELG
                     AETLDLAGVPLARRSVAWQLRADRVVPDLERLLVYAWRRHLAASAGRIVDQETASARMA
                     VGFADLVGFTRLSRQISETELARLVERFESRSADIVASSGGRMIKTLGDSVLWVSDSAA
                     RAADIALSLIQAHARVREMPELRVGLAIGPVIGRMGDVFGTTVNLASRLTSLAPAGGVL
                     ADPAIARELEDHPRFGLHAEDRQVVRGVGQLVPYVVTRA"
     misc_feature    complement(9015..9029)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            complement(9095..9886)
                     /locus_tag="AW272_RS37300"
     CDS             complement(9095..9886)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017605589.1"
                     /locus_tag="AW272_RS37300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_066375220.1"
                     /transl_table=11
                     /translation="MAGTSRRRLDTSVPHPARVWDYWLGGTDNFAPDRAVGDAITAVCP
                     QLPIIARAERQFIGRSVTLLAGDLGVDQFLDIGTGVPTAGNTHLVAQKVNPAARIVYVD
                     NDPMVLVHARDLLDSTPEGATDYLDADLRDPDPVLQAASDILDFARPIGLMLMGVVDFV
                     ADDTLASDAVNTLVDALAPGSYVAIASSTPSAEMDRAAEVWHAHGGTPIVLRDPDHLAR
                     FFEGLELLEPGVVSLPKWRPDAATDYIDREVCQYGGVGRKP"
     misc_feature    complement(9913..9931)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.73"
                     /tool="antismash"
     gene            complement(10001..12154)
                     /locus_tag="AW272_RS37305"
     CDS             complement(10001..12154)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017613248.1"
                     /locus_tag="AW272_RS37305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Geosmin synthase"
                     /protein_id="WP_066375134.1"
                     /sec_met_domain="T1TS (E-value: 4.9e-81, bitscore: 266.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAFTMPDFYVPYPARLNPHLERSHAHTMAWAKEMGMLDAPKPGG
                     GVVWTAEELDRMDYALMCAYTHPDCDGPALDLVTDWYVWVFFFDDHFLELFKHSRDFTG
                     AQKYLDRLELFMTATPPEPENPAEAGLKNLWERTIPQMSDDWRERFVVSTRNLMVESMW
                     ELENIDRGRVANPIEYVQMRRRVGGAPWSANLVEFAAGAEIPAHLAATRPLQVLCDTFS
                     DAVHLRNDLFSYQREVAEEGENSNAVLVLERFLGITTQEAAERVNDLLTSRLQQFETTA
                     LTEVPVLLADQAIPPHEQAAVALYAKGLQDWQSGGHEWHMRSSRYMNEGMVSKPKGLGM
                     STLRIGAEKRVRQHSHVPFERVGPQPVPEFHLPYVLRMSPHLDAARRYSIGWVKEMGIV
                     DGTIWDEPRFKGIDLAHCAAMINADGTLDEVCLTTDWLSWGTYGDDYYPVAFGATRDIP
                     RAKALNARLKLLMGDAPPVPVEPMEKGLADLWRRTAGDLPERARAGFRKSVEDMIDSWV
                     WELENQAANRIPDPIEYIEMRRRTFGSDMTASLARLASAEVVQDEIYQTRVMRELETAA
                     QDYACFTNDLFSYQKEIEFEGELHNIVLVVENFLDVDRVTARAIVLDLMNERMRQFEHI
                     LANGLPALLAMIGDPEVGRVLESHAAMLKDWMAGIMEWHRRCVRYQEPELLRLRGESLS
                     PLPLLRLLPSGLGTSAVRPRAAR"
     gene            12307..12966
                     /locus_tag="AW272_RS37310"
     CDS             12307..12966
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012894010.1"
                     /locus_tag="AW272_RS37310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_083959099.1"
                     /transl_table=11
                     /translation="MTIRVLIADDQAMIRTGLRLMAETEPGVDVVGEASDGRTAVELSR
                     SLRPDVLLLDIAMPVMSGLAAARILLDDDEAPRIVILTTFDTDENLHTALRLGVSGYLL
                     KSSPPEQLVEAIRTAAAGDSLIDPAVTLRVIAAFASTARLTLPPEIGTLSTREHEVLTG
                     LARGRSNREIADSLFVGEATVRSHVAQVLRKLGLRDRVQAVVFAYETGLIRPGGPQ"
     gene            12963..14036
                     /locus_tag="AW272_RS37315"
     CDS             12963..14036
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="AW272_RS37315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sensor histidine kinase"
                     /protein_id="WP_066375138.1"
                     /transl_table=11
                     /translation="MRWLLAAAVVVAGLVEAFGRPLQIAHPAPLALGAVAAGVILFFRS
                     RFPVVGLLALTVLGMVVVQGAYYPAWHFYSTLILAHTIGWAYELRTREGLLGVAAVLLT
                     WAHLNTRQWSDPAEVLISAVFIGGAYLTGVALRRQIDRTRRMAEHAARLELDRERAVAE
                     ERARIARELHDIVAHNVSLMTLHTGGVRRLLGTGHPREVDLLHGVEKAGREAIEELRLM
                     LGMLREPGETTPAGDLGDLVDQVRATGLEVRLSQAGDPRELPPGVDMSVYRIVQEALTN
                     VRKHAPAATRADVTLTYEPDTFTVSITDDGPGGAPGPGTGHGLIGMRERVTMHGGTLTT
                     SGSPAGYRVMATFPAKP"
     gene            complement(14073..14732)
                     /locus_tag="AW272_RS37320"
     CDS             complement(14073..14732)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW272_RS37320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_066375141.1"
                     /transl_table=11
                     /translation="MLRDPVRFFRTVAGTSLLVVPVLYVAGLLIDPAIRAGGGIGYYGA
                     HPGQVSISASVLHWSWVLLVPGILGMIHLARERTPVAAHVTGAIAVLGVINFSSLMLGD
                     FVYSRLERAMEPEAGSALADLALGDPGAEWGFRVPGFLGMLFVMVLALVMAYGKKAPWW
                     AGPAMLVGMLGTPIFPIGTVVGGLAYLAGAGVIGLRMLRMSDAEWAGPAGKLTAAR"
     gene            15003..15128
                     /locus_tag="AW272_RS45820"
     CDS             15003..15128
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW272_RS45820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_275527346.1"
                     /transl_table=11
                     /translation="MEKASPEAIEEPHLMLGMLREPGETTPRDAVTSTVAPQDRA"
     gene            complement(15367..18006)
                     /locus_tag="AW272_RS37325"
     CDS             complement(15367..18006)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040119.3"
                     /locus_tag="AW272_RS37325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6493 family protein"
                     /protein_id="WP_066375143.1"
                     /transl_table=11
                     /translation="MNPVLNLVTQTRLDDIPAAVAALDAAGRKELLAELTARLRQFADW
                     RFASDHRHEITGLRLAGALCHGGAAQVATWLNRRELRDPADAWADARAVVAALGERPLE
                     WRADLARRLVAALRAPRDANWSWRGRENGPPGYALARSMALETGVEPDGDVFVVCWAWH
                     VYLKGDLRNDPMATTMVPRLFDVEAAAAAFRSNFDGTGKFIDRLCAEVERGRFDRAMIL
                     DGTIGRFLIGGDARDTAVFVDLRRRLAPGLDEMPARDLVRCLPAGPANVADHVVEELYA
                     LDQAGRLDAGLFGEAVGALALRAEKKHVTAALKWISETFKVTKADPVRAEGALLAIADV
                     FAAETPATRTRAVRLAVKLGAPDDATRAAVADAAARLPADERAPLAAVFGVTDTAEEEV
                     FTGVPLVSAPPVAPPIRTAPELAIELRDIQYSSDHDALERVMAALAEMGHQGGGILATE
                     FKAEFQRAEWDDWKRFTDIPWDMGWMLTWAALLICDQADLVFRRRARTLLGLDRSLLER
                     FKDMVLPPRNPHERSNTPHTRMFRQRVTEVLCLAAAGETRPCLLATPTLPGHLVDPDTL
                     ISRLEDYGDREPLPADLAQALLRLPRDVDLSVADRAEKTGGPAGRAVAEWIRGGGLPDP
                     VIEWTVKVTTDRGYTDRKPAVTMEPPTRLPDHLDPLLRLSPRDDYVYWIHPRDIWPGVL
                     PNHPEATAAYLLRWVCNWAEQSEPAGEAVIPLALSPGPVGPVVAAAVVGAMGHHRALQR
                     SAAGEAFLALAGRPDYPADGIGDAIRRLVTGDVLKLNRITEVLGQSADAGAHTAVWEAL
                     SIALPGLLPEEGAKPRSGLGDLLGVAVKSARVCGAKGKVPGLAELAARKGSSRVNMEAR
                     SLLKLITE"
     misc_feature    complement(17764..17766)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18003..19343)
                     /locus_tag="AW272_RS37330"
     CDS             complement(18003..19343)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889868.1"
                     /locus_tag="AW272_RS37330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SWIM zinc finger family protein"
                     /protein_id="WP_066375225.1"
                     /transl_table=11
                     /translation="MSDAQIAYSYSRASELDLAAGLLGLSTSGGLTSSGLVARPHFFSG
                     LLTRAAPAAAALIGLADVAKTRYYDARAVTFMRDPVVTCNGDRLRFESFSACGGVYARL
                     DVLQEALDGDVVELGTTNVDVNVPLRKALARVGGNDPLHLAVGDDEVVATTLDGAVVEK
                     KVPLPERWLRGFAEVQVIASRFDLRASLGRAEAVKFVRDLPKKGVLWAVPAGRSLRLTA
                     RPAPGAVCLAGPERLAVLAPLLRFATGLRAYGPVVEGALPMASAWELELPGMRFTLTLS
                     PELRRGFSGEGAVLDDLTGDTVGDDADLVGALLRFEPRLDADLLAEQSGLTRARVGAAL
                     TRLGTGGRVGYDVAEAAHFHRELPYDAGRVLAMNPRLKSALGLVEQGAVHFTGPDVARV
                     GERTVRFVIGSTPTCTCPWWIDYRGSRGPCKHVLAAQKVASLVTVSA"
     misc_feature    complement(18828..18830)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(19278..19280)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    19383..19398
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.08"
                     /tool="antismash"
     gene            19400..20524
                     /locus_tag="AW272_RS37335"
     CDS             19400..20524
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018655603.1"
                     /locus_tag="AW272_RS37335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_066375145.1"
                     /transl_table=11
                     /translation="MSDLQQVVQTAIDELVEKGTERGVQVVVYVGGEPVVDAVAGVADP
                     VTGRAVTPGTPFYNYSVGKGATSAVLHVLAERGLIGYDTPIAEVWPEFAAHGKERATVR
                     MALNHTVGVPGIPLTTTEEDLCDWDRMCAAIAAAEPWWEPGTEIGYHAYSFGYIVGEIV
                     RRVTGKKISQVLLEEVAGPLGVADELYFGMPADQQPRLAVLEDAFSEPSPEPPAGLPTE
                     LPDLPMFRAGPMSLMPTAALGNRPDILAADIPAGGKMTARAMARLYSALMFEVDGVRLI
                     SPERLKEISAISAEGTDAVFGNPVRWSLGFGIGHPGGFAEPNPTTFGVPGAGGGSAYAD
                     TKTGMAFALMKNVLSPDFTTAATISDLVRRELAT"
     misc_feature    complement(20577..20590)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.29"
                     /tool="antismash"
     gene            20579..21406
                     /locus_tag="AW272_RS37340"
     CDS             20579..21406
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890469.1"
                     /locus_tag="AW272_RS37340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="metallophosphoesterase"
                     /protein_id="WP_066375147.1"
                     /transl_table=11
                     /translation="MTFLLAISDVHVGYPENRGIVERIRPRSQTDWLLLPGDVSEKVAD
                     FEWVLGTLARRFAKVVWAPGNHDLWTHPSETVQLRGVERYEHLVKVARDLGVVTPEDPY
                     PTWEGPDGPVTVAPLMVLYDYSYRMPGITTKEAALKVAYDKGVVCTDEMVLHPDPYDSI
                     DEWCAARVEETERRLADRPGGLPTVLVNHYPLVRDPTFVLRHPEFAIWCGTDRTADWHV
                     RFGALAMVYGHLHIPRTTWHDGVRFEEVSLGYPREWRPRAASPGELRQILPAH"
     misc_feature    20584..20598
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.91"
                     /tool="antismash"
     gene            21416..22051
                     /locus_tag="AW272_RS37345"
     CDS             21416..22051
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW272_RS37345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_066375155.1"
                     /transl_table=11
                     /translation="MIDTAQFDTVLFDVGGVLTVDPWQALWLTPGDGIADRLGLDHDQV
                     DRVGEDLWPQYSLRAREEADYWRDFGAALGRDIPADVVTAAEGSTLRTDPAASRVVSLL
                     VSRQISVGFISDNTSFWFPKQMSLLGEVVRTWPTHRYLSYLLGVSKQSTGTGLYEIAAR
                     SLDPSRTLVVDDRAHNIDRAASAGFQTRFYTLGGDSRLLDAIAESTDR"
ORIGIN
        1 cggcgagttc ccggtagggg ccccgcgctt cgcggacggc gaaggtccgg tagacgtcgg
       61 cggtgtccat ggcccgattc tcgtcgcggc gtcggtggtg cggggccggt cggcgccgga
      121 tacggcggga tgccgctcgg cgggcggtgc cgtggtgggc ggagccgtaa cggaaggaag
      181 tgctgttgac tgggggcgtg gaagaccaga tcgtcatcgg cgcccggttc aacgggccgc
      241 ccacgtcggc caacggcggt tacgtcagcg ggctggccgc cgcgttcgtc gacgggccgg
      301 cgcgggtgct gctgcggacg ccgccgccgc tggagacccc tcttgacgtc acccgcgacg
      361 gcgacaccgt ccgtgtcacg cacgacggcg tgctggtggt cgaagccggg ccgtcgagcg
      421 cggtattcct cgatcctccg gtacggccga cgttcggcga ggcctcggcc gcgcgcgacc
      481 ggcatccgtg gatcggcgcc gacaacctgc tgaccggctg tttcgtgtgc gggcacggcc
      541 gggccgacgg gctgcgggtc acccccgggc ggctggccga cgccgacgtg tgcgcgtcgc
      601 cgttcgagcc cgacgagacg gtcgccggcg acgggatcgt gcggccggag atcgtgtggg
      661 ccgcgctcga ctgtgtcagc tatccgccgt tcgcccaggg caccgacacg atcgccctcc
      721 tcggcacctt cgaggccgag atcgcgcgtt ccgttgcggc cggggaacgg ctggtcgccg
      781 tggggtggcc gctggagtcg tccgggcgga agctgttcag cgcctcggcg ctgctcgacg
      841 gtgacgaggt ggtcgcccgg gcccgcgcga cctggatcac gcttccgggt tgagccgtgg
      901 cccgtagtgt ggcgcccatg gatgtcgtac cacttgcgtg gaaagaaggc ggaacgccgg
      961 gagacatccc ggttgtcctg atacatggcc tgacgggcag ttcggccacg tgggaccgga
     1021 tcgccccggc cctcggacgg cactggatcg cgcccgatat gcggggccac ggcgccagcc
     1081 cgcgtcaccc cgactacagc ctcgaactga tggccgccga caccctcgcg ttcctcgacg
     1141 cccggggcct gacccggatc gacctcgtcg gtcactcgat gggcggcagg gtcgccgcgc
     1201 tggtcgcccg cgaccggccg gggctggtcc ggcggctggt gctggaggac tcgttccccg
     1261 ccgcgcacga accgcaggtc atcgagccct atgaggtgat cggcgacgag gacttcgacc
     1321 ccgccgtggt cgacgtgatc cggaccgacg tgcgcagggt cgaccccacg tggtgggccc
     1381 ggctgcccga actgaccatg ccggtgctgg tcgtcggggg cgggctgagc gagctcgtgc
     1441 cgcaggaggc gctggtggag ttcgccgagg cgctgcccga cgggcggcgg gtggtcctca
     1501 aggccgggca cagcgtccac aaggaggagc ccgacggtta cgtgaaggag gtcgcggctt
     1561 tcctccggtg acctcggcgg cgttaatggg ggcatggacg taccggagca cgaggatctg
     1621 gtccgtgatc tgctgaccct ccgcgagcgc gggctgatcc ggttacggga cgccgatctg
     1681 ccccacctgc gccgcgccgc cgccctgtgc caccccgcga ccgaccccgt cgccgccgtg
     1741 gagaagacgc tcagagacgc cgtcgggcgg ctcggcgagg gcacgctcgg ctccggggcc
     1801 gcgtacacgt tcgggctcgt ccagggcacc cgcgactggt cggccgccgc gcggcgcaag
     1861 cgggccgccg acgtctaccg gctgagcgtc gagcggttca ggaagaacca ggagcgcatg
     1921 ctgctggccc aggtcgccga ccagatcatc gcgctctgcg gcgcgggcgg cgaggccgcg
     1981 ctcccccgga tcgccgtcgg cgcccgcatc ccggtcgagt cggacggcgg gcgggcgatc
     2041 ctccagatcc ggccgatcga gctgatctcc ggggtcgacg tgctggtcaa ccccgagaac
     2101 gtctacctgg agatggcgcg ggtcttctcg cccagcgtgt cgggcgcgat caggaaggcc
     2161 gggtcacggc gcggtccggc cggggagctg ctcgacgaca ccgtccagcg cgagctgcac
     2221 gagtggatgg ccaagcacca ccgccccggc ctcaccgtcg cccccggcac ggtcgcgccc
     2281 accgggcccg ggtcgctggc gttcaacggg gtccggcggg tctaccacgc cgcggtcgcg
     2341 gtcccccggc ccgggaccga ccatcaggac gtcacgccgt cgacgatcat gctggccgtc
     2401 caccgggtgt tcgcgctggc ggaggaggag cgggtggcgt accgactgaa aaccatctgt
     2461 ttccccctgt tggggaccgg ccacggccgc ctggcggtgc ggcccggact gcactggctg
     2521 tggtcggcga tcagcgagaa cctggcccgc agccggggct gggaggtgca tctcagcgtg
     2581 ccggaaccag agaaggccga catcgtgctg cgccagctgt cgccctgacc cagcgcgccc
     2641 ggaggggttc ccgcagtcgc gccggtacgc cctccgcacc gccccccagc agtctgagcg
     2701 cccccgtgac gtaggtcgcg gccagcgtgg ggaggcgctg gagctcgggg ttgtccgcgc
     2761 cgttgccggg gatgcgggcg atgcgttcga ggacgccgtg cttgagtatg cggcgcaccg
     2821 ccgcgtcccg ggtctccgcc agagccacca gctcgacggc catggcgtag gtttcggccg
     2881 cgagcaatcc ccggccgaat tcgatgtcct cgccgcaggc cgccaggtgg tcgagatggg
     2941 cgccgtcgtg gatgccgcgc cagacccggc ggcggagctc cggcgcccgg tgggtgtggt
     3001 cgaccagcac cgtgatcagg ccccgctcgc cgggcaggcg catccaggtg cgccaggcga
     3061 gcccggtgaa ccgggagccg tcgaggatcg tgacgtcgcg ggtggcggcc gggcggtgcc
     3121 gttcgcccca gcggaggtgg tcgcgcaccg gcctgaccgg gccgtcgcgg tcggggatcg
     3181 tcgcgcacca ggcggccagc gcccggcagg cctcgcgggt ctcctctccc gggccgtcca
     3241 ccggaccggg gtcgtcggac gacgggtagc cgcgcgggac cgggcccgca cgacctcgca
     3301 gggcgcgcag ccggtcggcg gccggaccgc cgcgccggat gcgcgtggcc aggatgaccg
     3361 tgtcgagccc gtcgaaggcc gcggggccca gcagggcgca acccagggcg atctcggccc
     3421 acccgcgcac cgtccaggcg gcgtgctcgg cccccgacgc cgggacgtcc ctggcggcca
     3481 gggcccggcc cgccgcccag gcccacatgc ccgacgcgct ccgggtcagc gtcaccgcga
     3541 ccacagccgg atccggaaca tcagccgttg gagatcggcg aacgatgtcc ggccatggag
     3601 ggtccggtga ttgtcgacca gaaggacgtc cccgggcgcg agccgcacct ccaccggctc
     3661 gacccgaacc agcacatcgg tgaacaccga ggcggctgcc cgccacgaag attcaggaac
     3721 cggcaccagg ttgtcaggcc gccagcgcag cgtctccccg gcgaacaccg gcgcgggcgg
     3781 cgaactcctc cccgggttct cggagaagac ggccggggtg gtccaggacc actgggggcg
     3841 gcgtagggcg gcctcggcgc gggcgccctc ggggtggcgg cgcagggcgg tgagggcctg
     3901 gtctgcggac agcaggagcg agtggccgcc gtcgacggcc gggcggacgg cgaacaggca
     3961 gacgacgtct tccgggtcgg ggtggtactg ggcgtcggtg tgcagcggca cggggccact
     4021 ccgctgcgag aacgtgccgc cgagtgggcg ggggcggacc tcccagacgg gccggccgcc
     4081 gtcgcgggac gacgggcggc cgaaccgagc ggcgaaacgg agcgcctggg cgtgggtggg
     4141 cacgtcccag gagccccgta cgaccaccca tccccgcgtg gccagcctgt cctccgcctc
     4201 ggtcatttcg gtcacccgca ttggaagcct cctggtccgc cggtgagtgg tgcctccagg
     4261 gaagcggcat ccttggtgcg gtagccggtc gcgcagcggg caagacccgg gcgtttacgg
     4321 gttgaccctt gcgagagtca gctcatctca ctaaggttcg cccaacctta gtgagatata
     4381 ttcgcaagta atgagctcat atagggggaa ccaagcggtg ctagcccagg agcgaaggct
     4441 tgccgcgatc gccgcggcct ccgccgccgc cttccggcac agcgattacc accaggtccg
     4501 cgcggaggac gtcgccgaac gggtccgtct gccccggggt ggcgagaagg acaccggccg
     4561 ctccgccgtg tggctctaca acgaggtgcg cagccgccgc gtcctggtcg cgctcgccgc
     4621 caagcacgcc ttcgacgagt tcaccaccgg cgagagcccc tcagaaccgg tcacctcgat
     4681 gctcggcgcg gccgagtcgg tggccgccgc gctgcgccgc atcgcccgct tccaccaggt
     4741 cgaacgcttc ctgctggccc aggtcagact gggcatcggc gacatctcga cctcggagaa
     4801 gcgcccctcg gcggcccaga ctccccctgt ctggctcacc ggcacctacg gctcggccgc
     4861 cgcggcgggc tgggagggcc gggtgacggc gtacgccgaa tatctcgccc cccgcctcga
     4921 ccaggccgcc cgcgcggtcg cggtcccgac cgagagctgg gcgaaggaga gcgcggagcg
     4981 cctctccgaa ctggccttcc gcgcgatgtc cgatgacccc gacgcccccg ccgaccgcca
     5041 ggccgagggc ctggcggcct actggctggc ccgcgacctg atcccgctga ccggcgagtg
     5101 ggccgaccgc ctccacgccg ccgaacgcac ggccgagctg gtcgagaaga tcggccccaa
     5161 cggccgttcc cgcgcgaacg ccctggtcgt ggtgttccag gtgctgctcg acagcagccc
     5221 gctgctggtc cgcgcggccg aggtcggcgc cgacctggtg cccctgctga ccggctcccc
     5281 cgccgacggc ctgacgctgt gcgacgtgac gtcgcggcgc ggcctggccc tcctgcggct
     5341 gggcgacacc gccggcgcgc gggcctgttt cgaggagtcc cggcggatcg ccgagaagct
     5401 gcccgactcg gccgacccgg cgtccctgat cgcccgcgcc gaacacaacc tggccgaact
     5461 cctcgtcgac gagggcaagc cggagcgtgg ccgcgcgatc ctcgccgacg tggccgcccg
     5521 ccgcggcaac ggagtcccgc aggccggcgc gggccccgaa tggcgccggc acaccctcac
     5581 ccgccaggcg ctggcccgcg cgaccacgaa ggcgggccgg atcgtcgagg gcgtgagcct
     5641 ggccgagtcc acgctggccg accgcgaaga ccgcctcggc cccgacaacg tgaacaccgc
     5701 ctcggcccgg gtgaccctgg ccgaggccct gctcgccgcc gcccacccgg cccaggcccg
     5761 ccaccacctg accgaggcga tgcgcctgcg gtcgctctac ctcccgagcg agggtttctg
     5821 gcctcagtac gacctggtgc gcctcgccga gatagaactg cacgccgggt tcccggcgca
     5881 gacggtccgc ctcctcgacg aggcgacggt gacgacgacg tggttcgccg agcgcgtctc
     5941 cccccgcctc cacgaggagt ccgtcctggt gcggtcactg ggcatgatcc actccggcga
     6001 ggccctgacc gcactcaacg acctggccga gctcacccag acccgcgcgg tcctccgcgc
     6061 ccaggccgaa gcccgcctga ccgtcggcga cccggcgtcg gccgcccgcc tcctcgacga
     6121 catcgagggc gacggctccg tcaccgaccg ggccgagacg ctgctgctct ccgcccgcgt
     6181 ctccagcgcg ctcggccggg aggccgccgc cgaggaagcg tgccagtcgg tcgtggcgat
     6241 gggcggcgac cagatcgacg ccacccaccc aacggtgctt ggcgcccggc tgggcctcgc
     6301 cctgcagcgg gtgcgctcgg atcgggcggc cgaggtgggc gatctgctcg ctccgctgct
     6361 tgaccgccgg gccctcccgc acgggaagcc cgccctgggt gacgggcatc cgctgctggc
     6421 agaggccatg gcgctggcgg cccgcgcggg gtccccgccg acgcgtgcgc cggaagacca
     6481 gctgtgggag aacttctagt tgagccagct aaaggcaatg ttgttgagct gaccaaagag
     6541 aagtagccgc ggagcgccct tcgggtaagc cggaattcct gacgtcggcc cgggaatgag
     6601 ccgacaagag acgatcaaat caaacaaccg acccttacgc acaccacggc ctccagggct
     6661 cggcggcgtc gaagggcacc ggttgagcgt gacgacgcaa gcgatgttcg ccaatgcccg
     6721 aaacctgcgc gcgggccggg cgatgcggac cggcggcgcg aactcgcccc attccgaccc
     6781 cgccgcgcgt gcaccgcgcc gcaccaaacc ggttcataac acgcataggt gtccgaaata
     6841 ctgctgagcg tggaatcctc ctccttgatc gcgctgaccc cggcgctccc cctggccctg
     6901 gttctgctgg tcgcgggcgg tgccggcgtg gcagcggcgg gtgggctggg atatggctgg
     6961 gcggtggtgc gggcctgtct gcggggggtg ctgcagctcg gcgtcgtctc gctgatcatc
     7021 gcgtgggtgg tcgcgaacgg tctcgccgtc gccgggttca tcctggtcat gtacgccttc
     7081 gccacccata cggccgcgaa gcgcatcggc acctactggg cggcccttcc cgtcgccgcg
     7141 ggcagcgccc ccgtgctcgg tgtcctcacc gccaccggcg cggtcaccct cgacggcatg
     7201 gtgatcatcc ccgtcaccgg gatcgtcttc ggcggctgcc tgatcgccac cagcctggcc
     7261 ggtcgccgtg ccgccgacga gctcacgacc cggcacgggg aggtggaggc cgccatgtcg
     7321 ctgggcttca ccccgagaga cgcccggctg gagatctgcc gccccgccgc cgcccaggcc
     7381 ctggtgcccg ccctcgacca gaccagaacg gtcggcctgg tcaccctccc cggcgccttc
     7441 gtcggcatgc tcatcggggg cgcgaccccg gtggaggcgg gcatcgtcca gctcgtcgtc
     7501 ctggtcgcgc tgctctccgc ggaggccttc gccgtcgtgc tgacgatcga gctggccgcc
     7561 cgaggtcggc tgatcaggcc gtaaatttct cccccatatc gtgatatgtc ccgaatttgg
     7621 ggtcgccgga acgggcacgc ccatcccgaa ccgaaggggg tacaccagtg atcaagaagc
     7681 ttcacaacat gggcctcagg tcctcgcaca tgtacaccgc cgccatggcg tcgatcgggc
     7741 tgtccttctg tacgtgggtc gtctccaggc agatggagag tgccggcatc gaccgggccg
     7801 accgatgggg gatcttcatc ggccagtggg cgcccacgct catggccatg ggcgtggcac
     7861 tccgcgtcga agagacccac atgacggacg acgaaatgcg gaagatggac tccgacatgg
     7921 agatgggcac ccgcacgtcg ggcaactccc gggtccacgc tcccgcgagg tagaccccag
     7981 gagacccctg gggccgcccc ggaacgcatc cggccggggc ggcttcaggc accgaggctt
     8041 cgaggccttc gaggcacgtt caggctcggg tgaccacgta gggcaccagc tggcccacgc
     8101 cccgcacgac ctgacggtcc tccgcgtgca acccgaaccg cggatgatcc tccagttccc
     8161 gcgcgatcgc cggatcagcc agcacacctc cggcgggcgc cagcgaggtc agccgggagg
     8221 ccaggttcac ggtcgtcccg aagacgtcgc ccatccgccc gatcaccggc ccgatcgcca
     8281 ggccgaccct cagctccggc atctcccgca cccgcgcgtg cgcctggatc agggagagcg
     8341 cgatgtcggc ggcccgggcc gccgagtcgc tgacccacag gacggagtcg cccagggtct
     8401 tgatcatgcg tccgcccgac gaggccacga tgtcggccga gcggctctcg aagcgctcca
     8461 ccaggcgggc cagctccgtc tcggagatct ggcggctgag ccgggtgaac cccaccaggt
     8521 cggcgaatcc gacggccatc cgggccgacg cggtctcctg gtcgacgatg cgaccggccg
     8581 aggcggccag gtggcggcgc caggcgtaca cgagaaggcg ttccaggtcc gggacgaccc
     8641 ggtcggcgcg gagctgccag gcgacgctgc gccgggctag aggcacgccg gccaggtcga
     8701 gggtctcggc gccgagttcg gcctgcgact cggccaggcg ggcggaggcg cggcccaggg
     8761 agcgggccat cagcatgatg tgctcgtcgt cgtaggtgcc gtcggcgagc agggccatga
     8821 gggtgcgcag cgcctcgacg tcggcgtcgg tgaactcgat cgcgtcgtcg gcgacgttgg
     8881 cgaagcccag cgcgcgccag aaccggcggg cccggtggaa cggcacgccc gccatttgcg
     8941 cgacctgatg gctggtgtag cgacggggct ggcgaaggaa ggcctccgtc aggccgtcga
     9001 cccgcgggtc gtcaatcgac atacaagaag tgggcccgtc agtgggggaa aagtcttgcc
     9061 accagccact ttatccggct atcgcgtcaa atgttcaggg tttgcggccc acgcccccgt
     9121 actgacagac ctcccggtcg atgtagtcgg tcgccgcgtc aggacgccac ttcggcagcg
     9181 acaccacgcc gggctccagc agttccagcc cctcgaagaa gcgggccagg tggtctgggt
     9241 cgcgcagcac gatcggggtg ccgccatggg cgtgccagac ctcggccgcc ctgtccatct
     9301 ccgcgctcgg cgtactgctg gcgatggcca cgtagctgcc cggcgcgagg gcgtcgacca
     9361 gggtgttcac cgcgtcggac gcgagggtgt cgtcggcgac gaaatcgacc acccccatca
     9421 gcatcagccc gatcggccgg gcgaagtcca gaatgtcgga ggcggcctgg aggaccgggt
     9481 cggggtcgcg caggtcggcg tcgaggtagt cggtggcgcc ctcgggcgtg ctgtcgagca
     9541 ggtcccgggc gtgcaccagc accatcgggt cgttgtcgac gtacacgatc ctggcggccg
     9601 gattgacctt ctgggccacc agatgggtgt ttcccgcggt ggggacgccg gtgccgatgt
     9661 cgaggaactg gtcgacgccg agatcgccgg ccagcagggt gaccgaccgg ccgatgaact
     9721 ggcgctcggc gcgggcgatg atcggcagct gggggcagac ggcggtgatg gcgtcaccga
     9781 ccgcgcggtc gggggcgaag ttgtcggtgc cgccgagcca gtagtcccag acccgggcgg
     9841 ggtggggtac ggaggtgtcg aggcgccgcc gtgatgtgcc ggccatctcc actcccccat
     9901 ccgaacaccc tcttaggcca acctaacctc cgcgtccttc gggcatggcg aagcggagcc
     9961 cgtgatccgg tcacgaactc cgctcgcggc gggaaaaggc ctaacgggcg gcccgggggc
    10021 gtaccgccga cgtgcccagg cccgagggca gcagccgcag cagaggaagc ggcgacagcg
    10081 actccccgcg cagccggagc agttcgggct cctggtagcg aacgcagcgg cggtgccact
    10141 ccatgatccc ggccatccag tccttgagca tggcggcgtg gctctccagc acccggccga
    10201 cctcgggatc gccgatcatg gcgagcaggg cggggagacc gttggcgagg atgtgctcga
    10261 actgacgcat ccgctcgttc atcaggtcga gcacgatggc ccgcgcggta acccggtcga
    10321 cgtcgaggaa gttctccacg accaggacga tgttgtgcag ctcaccctcg aactcgatct
    10381 ccttctggta ggagaacagg tcgttggtga agcacgcgta gtcctgcgcc gcggtctcca
    10441 gttcccgcat gacgcgggtc tggtagatct cgtcctggac gacttcagcc gacgccagcc
    10501 gggccaggct ggccgtcatg tcggagccga aggtccggcg gcgcatctcg atgtattcga
    10561 tggggtcggg gatccggttg gccgcctggt tctccagctc ccacacccag ctgtcgatca
    10621 tgtcctcgac cgacttcctg aacccggccc gcgcccgttc gggcagatct ccggcggtac
    10681 gccgccacag atccgccagc cccttctcca tcggctcgac gggcaccggc ggcgcgtcac
    10741 ccatgagcag tttgagccgc gcgttcagcg ccttggccct cggaatgtcg cgggtggcgc
    10801 cgaaggcgac cgggtagtag tcgtcgccgt aggtgcccca gctcagccag tcggtggtca
    10861 ggcagacctc gtccagcgtc ccgtcggcgt tgatcatcgc ggcgcagtgg gccaggtcga
    10921 tgcccttgaa gcggggttcg tcccagatcg tcccatcgac gatccccatc tccttgaccc
    10981 agccgatcga atagcgccgg gccgcgtcga ggtgggggct catccgcagc acgtagggca
    11041 ggtggaactc cggcaccggc tgcggcccga cccgctcgaa cggcacgtgg gagtgctgcc
    11101 ggacgcgctt ctccgccccg atcctcaacg tggacatccc caggcccttg ggcttggaga
    11161 ccatgccctc gttcatgtag cggctggacc gcatgtgcca ctcgtggccg cccgactgcc
    11221 aatcttgcag gcccttggcg tagagggcga cggcggcctg ctcgtggggc gggatggcct
    11281 ggtcggccag cagcaccggg acctcggtca gcgcggtcgt ctcgaactgc tgcaaccggg
    11341 aggtcagcag gtcgttgacg cgttcggcgg cctcctgcgt ggtgatgccg aggaacctct
    11401 ccagcaccag cacggcgttg gagttctcgc cttcctcggc cacttcgcgc tggtaggaga
    11461 acaggtcgtt gcgcaggtgg acggcgtcgg agaaggtgtc gcagagcacc tggagcggcc
    11521 gggtggcggc caggtgggcg gggatctcgg ccccggcggc gaactcgacg aggttggccg
    11581 accagggggc cccgccgacg cggcggcgca tctggacgta ttcgatcggg ttggcgaccc
    11641 gcccccggtc gatgttctcc agctcccaca tcgactcgac catcaggttg cgggtggaga
    11701 cgacgaaccg ctcgcgccag tcgtcggaca tctggggaat cgtgcgttcc cacaggttct
    11761 tgagcccggc ctcggccggg ttctccggct cgggcggggt ggcggtcatg aagagttcga
    11821 gccggtcgag atacttctgc gcgccggtga agtcgcggga gtgcttgaac agctccagga
    11881 agtggtcgtc gaagaagaac acccacacat accagtcggt gaccaggtcg agggccgggc
    11941 cgtcacagtc gggatgggtg tacgcgcaca tcagcgcgta gtccatgcgg tcgagctctt
    12001 ctgcggtcca gacgacgccg ccccccggtt tgggggcgtc gagcatgccc atctccttcg
    12061 cccacgccat cgtgtgggcg tgggaacgtt ccaggtgcgg gttgagccgg gcgggatacg
    12121 ggacgtagaa gtcgggcatg gtgaaggcct tcaagagcgt cctctcctcg ggggcggggc
    12181 gggtactcgc cgtgacgaca ctggcacttt ccgtgggatc accgcaagcc cctcacccgt
    12241 cacgatgaac cggtctccgc ctcgcggcgg aggagtcggc tttgttctgt tctgtacgct
    12301 ccccaggtga caatcagggt gctcatcgcc gatgaccagg cgatgatccg cacaggcctg
    12361 cgcctgatgg ccgagaccga accaggcgtc gacgtggtcg gcgaggcgtc cgacggccgg
    12421 acggcggtcg agctgagccg ctccctgcgg cccgacgtcc tcctcctcga catcgcgatg
    12481 cccgtcatgt ccggcctggc ggccgcccgg atcctcctgg acgacgacga ggcaccgcgc
    12541 atcgtgatcc tcacgacgtt cgacaccgac gagaacctgc acaccgcgct gcgcctgggc
    12601 gtcagcggct atctgctgaa gtcgtccccg cccgaacagc tcgtcgaggc gatcaggacg
    12661 gccgccgccg gagacagcct gatcgacccc gccgtcaccc tccgggtgat cgccgccttc
    12721 gcctccaccg cccggctgac cctcccaccc gagatcggca ccctgtccac ccgcgaacac
    12781 gaggtgctca ccggcctggc caggggccgc tcgaaccgcg agatcgccga ctcgctcttc
    12841 gtcggggagg cgacggtacg cagccacgtc gcccaggtgc tgcgcaagct gggcctgcgc
    12901 gaccgcgtgc aggcggtcgt gttcgcctac gagacgggcc tgatccggcc gggaggcccc
    12961 cagtgagatg gctgctggcg gcggccgtgg tcgtggcagg cttggtcgag gcattcggac
    13021 gtccgctgca gatcgcccac ccggcaccgc tggccctggg cgcggtggcg gccggggtga
    13081 tcctgttctt ccggtcgcgc ttccccgtcg tcgggctgct ggcgctgacc gtgctcggga
    13141 tggtggtggt ccagggcgcc tactatccgg cctggcactt ctactcgacg ctgatcctgg
    13201 cccacacgat cgggtgggcc tacgaactgc gcacccgcga gggcctgctc ggcgtggcgg
    13261 cggtcctgct gacctgggcc catctgaaca cgcgccagtg gagcgacccc gccgaggtgc
    13321 tgatctcggc cgtcttcatc ggcggcgcct acctgaccgg cgtggccctg cggcggcaga
    13381 tcgaccggac ccgccggatg gccgagcacg ccgcccgcct ggaactcgac cgcgaacgcg
    13441 ccgtggcgga ggaacgcgcc cggatcgcca gggaactgca cgacatcgtg gcccacaacg
    13501 tgagcctgat gacgctccac acgggcggcg tccgccggct gctcggcacc ggccacccgc
    13561 gcgaggtcga cctgctgcac ggcgtggaga aggccggccg ggaggcgatc gaggaactgc
    13621 gcctgatgct cggcatgctc cgcgaacccg gcgagaccac accggccgga gacctcgggg
    13681 acctggtcga ccaggtccgc gcgaccggcc tggaggtgcg gctctcacag gccggcgacc
    13741 cgcgcgagct gcctcccggg gtggacatgt cggtctaccg gatcgtccag gaggccctga
    13801 cgaacgtccg caaacacgcg ccggccgcca cccgcgccga cgtgaccctg acctacgaac
    13861 cggacacctt caccgtctcg atcaccgacg acggccccgg cggcgccccg ggccccggca
    13921 ccggccacgg cctgatcggc atgcgcgaac gcgtcaccat gcacggcggg acactgacga
    13981 ccagcggctc ccctgcgggc taccgggtga tggcgacatt cccggcgaag ccttaggccg
    14041 accgcgagtc caccgcaacc ggccccgtgc ggctatcggg ccgccgtgag cttcccggcc
    14101 gggcctgccc attcggcgtc gctcatccgg agcatccgga gcccgatgac ccccgctccg
    14161 gcgaggtagg cgagcccgcc gacgacggtc ccgatgggga agatcggcgt cccgagcatg
    14221 ccgaccagca tggccggccc cgcccaccag ggcgctttct tcccgtacgc catcaccagc
    14281 gccagcacca tcacgaagag cattccgagg aagccgggga cgcggaaccc ccactcggcg
    14341 cccggatcgc ccagggccag atcggcgagc gccgaccccg cctcgggctc catcgcccgc
    14401 tccagccgcg agtagacgaa gtcacccagc atcagcgacg agaagttgat gaccccgagc
    14461 accgcgatcg ccccggtgac gtgcgccgcg accggcgtcc gctccctggc caggtggatc
    14521 atgccgagga tccccgggac gagcagcacc cacgaccagt gcagcaccga ggcgctgatc
    14581 gagacctgac cgggatgggc gccgtagtag ccgatgcccc cacccgcccg gatcgcggga
    14641 tcgatgagga gaccggcgac atacaggacc ggaacgacca ggagactggt tccggcgacg
    14701 gtccggaaga accggacggg atcacggagc attgcggcac taccttccaa cgaatctgca
    14761 cttgacgtgc gggaaggcta gggaccggac acacgtgcgg gcgtcccccg cgacgaggag
    14821 gcgatgtccc ccacgacgct gaacgcgagg gctttccacc cggcatccgc gcgaggccgt
    14881 cctgctgcac ggacgcgagg ccgacccgcg agaccgacct gccgcacgga cgcgagaccg
    14941 acctgctcca cggacgcaag accgacctgc cacacagacg cgaggccgac cgactgcacg
    15001 gagtggagaa ggccagcccg gaggcgatcg aggaaccgca cctgatgctc ggcatgctcc
    15061 gcgaacccgg cgagacgaca ccccgcgacg cggtcacatc gaccgtcgct cctcaggacc
    15121 gcgcctgaac cttggggggc gccgcagccc ctcccacagt tcctcaaggc gctggagaag
    15181 gtccaggcga ccgggaaggt cccgctggcc tcgggtcgca atgggcaccg ctggatgcct
    15241 caggaggtct gcccgacttt gaccgcttcg tggatggtct gggggacgcg gtagccgtaa
    15301 ccgaaaatgg cggttcgggg ggcggacctg acccgggtac cgatcttgcg atccgcccac
    15361 agccgcctat tcggtgatca gtttcagcag tgacctggcc tccatgttca cccggctgga
    15421 ccccttccgg gccgccagct cggccagccc cggcaccttc cccttcgcgc cgcagactcg
    15481 ggccgacttc accgccaccc ccagcaggtc gcccagcccc gagcgcggct tggcgccctc
    15541 ctcgggcagc aggccgggca gcgcgatcga cagcgcctcc cacaccgcgg tgtgggcgcc
    15601 cgcgtcggcc gactggccga ggacctcggt gatgcggttg agcttgagga cgtcgcccgt
    15661 caccagccgg cggatcgcgt caccgatgcc gtcggcgggg tagtcggggc ggcccgccag
    15721 ggcgaggaag gcctcgccgg ccgccgagcg ctggagcgcg cgatggtggc ccatcgcgcc
    15781 gacgaccgcg gccgccacca ccgggccgac cgggccgggg ctcagcgcga gcgggatgac
    15841 cgcctcgccc gccggttcgc tctgttcggc ccagttgcag acccagcgga gcaggtaggc
    15901 ggccgtggcc tcggggtggt tggggagcac gccgggccag atgtcgcgcg ggtggatcca
    15961 gtagacgtag tcgtcgcgcg gggacaggcg gagcagcggg tcgaggtggt cggggagccg
    16021 ggtgggcggc tccatcgtga cggccggctt gcggtcggtg taaccgcggt cggtcgtgac
    16081 cttgaccgtc cattcgatga cggggtcggg caggccgccg ccgcggatcc actcggccac
    16141 ggcgcggccg gccgggccgc cggtcttctc cgcgcggtcg gcgaccgaga ggtcgacgtc
    16201 gcggggcagc ctgaggagcg cctgggcgag gtcggcgggc agcggttcgc ggtcgccgta
    16261 gtcctccagc cggctgatca gggtgtcggg gtcgacgagg tggccgggca gagtgggagt
    16321 ggccagcagg cagggccggg tctcgccggc ggcggccagg cagaggacct cggtgacccg
    16381 ctgccggaac atccgggtgt ggggcgtgtt cgaccgctcg tgggggttgc ggggcgggag
    16441 caccatgtcc ttgaaccgtt cgaggagcga ccggtcgagg ccgagtagcg tccgggcccg
    16501 gcggcggaac accaggtcgg cctggtcgca gatgagcagg gccgcccagg tcagcatcca
    16561 gcccatgtcc caggggatgt cggtgaaccg cttccagtcg tcccactcgg cccgctggaa
    16621 ctcggccttg aactcggtgg ccaggatgcc cccgccctgg tggcccatct cggccagcgc
    16681 ggccatgacg cgttcgaggg cgtcgtggtc ggaggagtat tggatgtctc gcagctcgat
    16741 cgcgagttcc ggcgcggtgc ggatcggggg cgcgaccggt ggggcgctga ccagggggac
    16801 gccggtgaac acctcttctt cggccgtgtc ggtcacgccg aagacggcgg ccagcggcgc
    16861 gcgttcgtcg gcgggcagcc tggcggccgc gtcggcgacg gccgcccggg tggcgtcgtc
    16921 gggggcgccg agcttgaccg cgagccggac cgcgcgggtg cgggtcgcgg gggtctcggc
    16981 ggcgaacacg tcggcgatgg cgagcagggc gccctcggcc cggacggggt cggccttggt
    17041 gaccttgaag gtctcggaga tccacttgag cgcggcggtg acgtgtttct tctccgcccg
    17101 cagcgccagc gcgccgacgg cctcgccgaa cagcccggcg tcgagccgcc cggcctggtc
    17161 gagcgcgtag agctcctcga cgacgtggtc ggcgacgttg gcgggcccgg cgggcaggca
    17221 gcggacgagg tcgcgggcgg gcatctcgtc gaggcccggg gcgaggcggc ggcggaggtc
    17281 gacgaagacg gcggtgtcgc gggcgtcgcc gccgatcagg aaccggccga tcgtgccgtc
    17341 gaggatcatg gcccggtcga accggccccg ctccacctcg gcgcacagcc ggtcgatgaa
    17401 cttcccggtg ccgtcgaaat tgctgcggaa ggcggccgcc gccgcttcga cgtcgaacag
    17461 gcgcggcacc atcgtcgtgg ccatcgggtc gttccgcaga tcgcccttca ggtagacgtg
    17521 ccacgcccag cagacgacga acacgtcgcc gtcgggctcg acgccggtct ccagcgccat
    17581 ggacctggcc agcgcgtatc cgggcgggcc gttctcccgc ccgcgccacg accagttggc
    17641 gtcgcgcggc gcccggaggg cggccaccag acgccgcgcc aggtcggccc gccattcgag
    17701 cggacgctcg ccgagcgcgg cgacgacggc ccgcgcgtcg gcccacgcgt cggcggggtc
    17761 gcgtaactcg cgccggttga gccaggtggc gacctgggcg gcgccgccgt ggcagagcgc
    17821 gcccgcgagc cgcagcccgg tgatctcgtg tctgtggtcg ctcgcgaacc gccagtcggc
    17881 gaactggcgc agccgcgcgg tcagctcggc caggagttcc ttccgcccgg ccgcgtcgag
    17941 ggcggcgacg gcggcgggga tgtcgtcgag acgagtctgc gtgacgaggt tgagcacggg
    18001 gttcatgccg acaccgtcac cagggacgcg accttctggg cggccagtac gtgtttgcac
    18061 ggcccccgcg accctcggta gtcgatccac cagggacagg tgcaggtggg cgtcgagccg
    18121 atgacgaatc ggacggtccg ttcgccgacc cgggccacgt cgggcccggt gaagtggacg
    18181 gcgccctgtt cgaccaggcc gagggccgac ttgaggcggg ggttcatggc cagcacgcgg
    18241 ccggcgtcgt agggcagttc gcggtggaag tgggcggcct cggcgacgtc gtagccgacc
    18301 cggccgccgg tgccgagccg ggtgagggcg gcgccgacgc gggcgcgggt caggcccgac
    18361 tgctcggcga gcaggtcggc gtcgaggcgg ggctcgaagc gcagcagcgc gcccaccagg
    18421 tcggcgtcgt cgcccacggt gtcgccggtc aggtcgtcga ggactgcccc ctcgccggag
    18481 aatcctcgcc tcagctcggg tgacagggtg agcgtgaacc gcatgccggg cagctccagc
    18541 tcccacgccg acgccatcgg cagggcgccc tcgacgaccg ggccgtaggc gcgcaggccg
    18601 gtcgcgaagc gcagcagcgg cgcgagcacg gccagccgct cgggcccggc caggcagacc
    18661 gcgccgggcg ccggacgcgc cgtcagccgc agcgaccgcc cggcgggcac cgcccacagc
    18721 acgcccttct tgggcaggtc gcgcacgaac ttcacggcct cggcccggcc cagcgaggcg
    18781 cgcaggtcga accgggaggc gatcacctgg acctcggcga agccgcgtaa ccagcgctcg
    18841 ggcagcggca ccttcttctc gaccacggcg ccgtcgagcg tggtggcgac cacctcgtcg
    18901 tcgcccacgg ccaggtggag ggggtcgttg ccgccgacgc gggccagcgc cttgcgcagc
    18961 ggcacgttca cgtcgacgtt ggtggtgccg agttcgacca cgtcaccgtc gagcgcctcc
    19021 tgcagcacgt cgagccgcgc gtagacgccg ccgcaggccg agaacgactc gaaccgcagc
    19081 cggtcgccgt tgcaggtcac caccgggtcg cgcatgaacg tcacggcgcg cgcgtcgtag
    19141 tagcgcgtct tggccacgtc ggcgagcccg atcagggcgg ccgcggcggg cgcggcacgg
    19201 gtcagcagcc cgctgaagaa atggggccgg gcgaccaggc cggacgaggt gagcccgccg
    19261 gaggtggaca ggcccagtaa gccggcggcc aggtcgagtt cggaagctcg cgaataggag
    19321 tacgcgatct gcgcgtcaga catggccagg accctagcgg cggcgaccga cattccaaga
    19381 acacgctaga atcgaacaca tgagcgatct tcagcaggtc gtacagaccg cgatcgacga
    19441 actcgtcgag aagggcaccg aacgtggtgt ccaggtggtg gtctacgtcg gcggtgagcc
    19501 cgtggtcgac gcggtggcgg gggtggccga tccggtgacc gggcgcgcgg tgactcccgg
    19561 cacgccgttc tacaactact ccgtgggcaa gggcgccacc tcggccgtgc tccacgtcct
    19621 ggccgaacgg ggtctgatcg gctacgacac gccgatcgcc gaggtgtggc ccgagttcgc
    19681 cgcccacggc aaggagcgcg cgacggtccg catggcgctc aaccacacgg tgggcgtgcc
    19741 cggcatcccg ctcaccacga cagaagagga tctctgcgac tgggaccgca tgtgcgcggc
    19801 gatcgcggcg gccgagccgt ggtgggagcc gggcaccgag atcggctacc acgcctacag
    19861 cttcggctac atcgtgggtg agatcgtccg gcgggtcacc ggcaagaaga tctcccaggt
    19921 cctgctcgaa gaggtcgcgg ggccgctcgg cgtcgccgac gagctctact tcggcatgcc
    19981 ggccgatcag cagccccggc tggccgtcct cgaagacgcg ttctccgagc cgtcccccga
    20041 gccgcctgcg gggctgccca ccgagctgcc cgacctgccg atgttcaggg ccggcccgat
    20101 gtcgctgatg ccgaccgccg cgctcggcaa ccggcccgac atcctggccg ccgacatccc
    20161 cgccgggggc aagatgacgg cccgcgcgat ggcccggctc tactcggcgc tgatgttcga
    20221 ggtcgacggc gtccggctga tctcgccgga gcggctgaaa gagatctccg cgatctccgc
    20281 ggagggcacc gacgcggtct tcgggaaccc cgtcaggtgg agcctcggct tcggcatcgg
    20341 tcacccgggc ggtttcgccg agccgaaccc gaccacgttc ggcgtccccg gcgcgggcgg
    20401 cggcagcgcc tacgccgaca cgaagacggg catggccttc gccctgatga agaacgtcct
    20461 cagccccgac ttcaccacgg cggccacgat cagcgacctg gtgcggcggg aactcgccac
    20521 ctgacgggga gcggctcgca ggtggatttg ggcgaccagg ttggagagac tgccccttat
    20581 gacatttctt ctggcgatca gcgatgtgca cgtcggttac ccggagaacc gcggcatcgt
    20641 cgaacgcatc cggccccggt cgcagaccga ctggctgctg ctgcccggag acgtgtccga
    20701 gaaggtcgcc gacttcgaat gggtgctggg caccctcgcg cgccgcttcg ccaaggtcgt
    20761 ctgggcgccg ggcaaccacg acctgtggac ccacccgagc gagacggtcc agctccgcgg
    20821 cgtcgagcgc tacgaacacc tcgtgaaggt ggcccgtgac ctgggcgtcg tcacccccga
    20881 agacccctac ccgacgtggg agggccccga cggcccggtg acggtcgcgc cactgatggt
    20941 cctctacgac tactcctacc gcatgcccgg catcaccacg aaagaggcgg ccctgaaggt
    21001 cgcctacgac aagggcgtgg tgtgcaccga cgagatggtc ctgcaccccg acccctacga
    21061 cagcatcgac gagtggtgcg ccgccagggt cgaggagacc gaacgccgcc tggccgaccg
    21121 cccgggcggc ctcccgacgg tgctggtcaa ccactatccg ctggtccgcg accccacgtt
    21181 cgtgctgcgc cacccggagt tcgcgatctg gtgcggcacc gaccgcaccg ccgactggca
    21241 cgtcaggttc ggcgcgctcg ccatggtcta cggccatctc cacatcccgc gcacgacctg
    21301 gcacgacggc gtccgcttcg aagaggtctc cctgggctac ccgcgagagt ggcgccccag
    21361 ggcggcgtct ccgggcgagc tccggcagat cctcccggcc cactgatcgc cgcgcatgat
    21421 cgacaccgca cagttcgaca ccgtgctgtt cgacgtcggc ggggtcctga cggtcgaccc
    21481 gtggcaggcg ctgtggctga ccccgggaga cggcatcgcc gaccggctcg gcctcgacca
    21541 tgaccaggtc gacagggtcg gcgaggacct gtggccgcaa tactccctgc gggcgcggga
    21601 ggaggcggac tactggcgcg acttcggcgc cgctctcggc cgcgacatcc cggccgacgt
    21661 cgtcaccgcg gcggagggct cgacgctgag aaccgatccg gcggcgtcgc gggtggtcag
    21721 cctgctcgtc agccggcaga tctcggtcgg cttcatcagt gacaacacct cgttctggtt
    21781 tcccaaacag atgagtcttc tcggtgaagt ggtgcgcacc tggccgactc accgatactt
    21841 gtcctatctt ctcggtgtgt ccaaacagag caccggaacg ggcctctacg aaatcgccgc
    21901 ccgatcactc gacccgtcgc gcaccctggt cgtcgacgac cgggcgcaca atatcgacag
    21961 ggccgcgagc gcgggtttcc agacgcggtt ctacacgttg ggcggcgatt cccggctgct
    22021 cgacgcgatc gcggagagca cggaccggta gcgtgcgatt cttacgccgc gatcctccac
    22081 ctcccccgct ggagattcag gagctcggcc gcgggaccca ggccttccag gccatgctgg
    22141 tcgaatacaa ctgg
//
