LOCUS       NZ_BBXD01000026        26373 bp    DNA     linear   CON 08-AUG-2024
DEFINITION  Herbidospora mongoliensis strain NBRC 105882, whole genome shotgun
            sequence.
ACCESSION   NZ_BBXD01000026
VERSION     NZ_BBXD01000026.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Herbidospora mongoliensis
  ORGANISM  Herbidospora mongoliensis
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Herbidospora.
REFERENCE   1
  AUTHORS   Komaki,H., Ichikawa,N., Oguchi,A., Hamada,M., Tamura,T. and
            Fujita,N.
  TITLE     Genome-based analysis of non-ribosomal peptide synthetase and type-I
            polyketide synthase gene clusters in all type strains of the genus
            Herbidospora
  JOURNAL   BMC Res Notes 8, 548 (2015)
   PUBMED   26452464
  REMARK    DOI:10.1186/s13104-015-1526-9 Publication Status: Online-Only
REFERENCE   2  (bases 1 to 171251)
  AUTHORS   Hosoyama,A., Oguchi,A., Ichikawa,N., Kimura,A., Ohshita,R. and
            Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-MAY-2015) Contact:Director-General Department Of
            Biotechnology National Institute of Technology and Evaluation,
            Biological Resource Center (NBRC); 2-49-10 Nishihara, Shibuya-ku,
            Tokyo 151-0066, Japan URL :http://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Noncontiguous Finished
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: newbler v. 2.6
            Genome Coverage                   :: 62x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001570545.1-RS_2024_08_08
            Annotation Date                   :: 08/08/2024 02:40:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,280
            CDSs (total)                      :: 8,202
            Genes (coding)                    :: 8,113
            CDSs (with protein)               :: 8,113
            Genes (RNA)                       :: 78
            rRNAs                             :: 4, 6, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 4, 5 (5S, 16S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 21 of 89
            Pseudo Genes (incomplete)         :: 71 of 89
            Pseudo Genes (internal stop)      :: 4 of 89
            Pseudo Genes (multiple problems)  :: 7 of 89
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:23:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 81778
            Orig. end                         :: 108151
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBXD01000026.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26373
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26373
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26373
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16373](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16373
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    complement(471..491)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 22.41"
                     /tool="antismash"
     misc_feature    complement(1277..1295)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.89"
                     /tool="antismash"
     misc_feature    complement(1407..1419)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.6"
                     /tool="antismash"
     misc_feature    complement(1425..1439)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.06"
                     /tool="antismash"
     gene            complement(1567..1980)
                     /locus_tag="AW272_RS46180"
     CDS             complement(1567..1980)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024420.4"
                     /locus_tag="AW272_RS46180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3883 domain-containing protein"
                     /protein_id="WP_369408824.1"
                     /transl_table=11
                     /translation="MIELQGEFETLHRPDLATECTRVSLISDYFGYDITAPTLDGSSIR
                     RLEVKTQTAEELLSSFRFYLTRNEYDVGRSNPTEWSMVACSRVTLGDEIRILGWCRAAT
                     LSPYLPVDQGGRWTEALALIPTSLLTPGLPPPL"
     misc_feature    complement(1582..1584)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(1840..1842)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            1945..2100
                     /locus_tag="AW272_RS45410"
     CDS             1945..2100
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW272_RS45410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_245657899.1"
                     /transl_table=11
                     /translation="MQRLELALQFYQNKFFSSSADIAAINFPVALGNQALDSRRNGIFI
                     AGGSET"
     gene            complement(2323..3795)
                     /locus_tag="AW272_RS41405"
     CDS             complement(2323..3795)
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012403.4"
                     /locus_tag="AW272_RS41405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_169807704.1"
                     /transl_table=11
                     /translation="MRHGANFSVPGAGKTTVTYTLHLGERGAGRVDKLLVVAPLSAFEA
                     WEEEALQVVDPPLTTARWTGPLEHNPDVVIVNYQKLRNALPDLASWMGDHSVHLVIDEA
                     HRAKRGSMGEWGRGLLALAPLAARRDILTGTPAPNHPRDLVALIDILWPGGMASKSAPR
                     AALVAEPTTDSMNALNNFIEPLYVRTTKADLRLPPVTFVPVAPIQMGPVQKDIYDAMVQ
                     RYAGLVDLGRRDAEMFARLGEVTMYLIQAASSPQLLASSANPSRAYRFPPLTIPPGSPL
                     GRMIETYSEYEIPPKIAEACKIVFRNAQQNRKTLVWSNFPGNLLALERQLAGLKPAIVY
                     GGIPSADDADPGVRTRERELTRFRRDSDCKVLLANPAAMAEGVSLHHECHDAIYIDRTF
                     NAGQYLQSLDRIHRLGLAEDTETRIYLLTTEGTIDERIHNRVRAKMVRLGQMLADPGLV
                     PLALPDDEYFGLELDDELDLQEVLTHLASGAS"
     misc_feature    complement(2350..2352)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(3829..3843)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    4025..4040
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 23.05"
                     /tool="antismash"
     gene            complement(4200..5612)
                     /locus_tag="AW272_RS36440"
     CDS             complement(4200..5612)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW272_RS36440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_066374725.1"
                     /transl_table=11
                     /translation="MTEAARRQHILKALEAHGQLENGERRPFPLSRGSTNLPVVTLPLS
                     VPILNAKSFRIAPALADHSSSEAVAADPESPAAQKLIAELVSESHKFAEELKRSLREEG
                     QDEPGIITRSGVLINANTRCVLMRELLAEGELRNDAIRVAVLPSDTGPGELYDLEAVVQ
                     KQRDHKDDYDLVSELMMLRTLHEEGQMTEQQIAKRQRLNPKDVVLRFRLLALMDRARVL
                     VDPPIPIKSFGSGRKKGALQNWRELDTRVQAIDEREGPEAGDDHIREWLHLHLLDMGSV
                     HNLRVATQGWVNKHLMNALTHGGEIGTKIAAAATDTKPALEPKTDPGGDGLDLLDFGRS
                     SEDKPAGNAVRSLLNLTIAATNAGPRGVVELPDGSRHSGNEILKVLRDTTDAGLKDSSM
                     RIDAGEKLEAPSRLIEKAHAALVAANKAIYDVQDQVEFAKAAEGVTSLLDDLVVQIDEA
                     REALEQITARHS"
     misc_feature    complement(4788..4790)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6291..6857)
                     /locus_tag="AW272_RS42835"
     CDS             complement(6291..6857)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.4"
                     /locus_tag="AW272_RS42835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="N-acetyltransferase"
                     /protein_id="WP_169807705.1"
                     /transl_table=11
                     /translation="MTAGIATQTLSGSLALPFGPTVSALYQQVFRLPPFHTDDAGFAGQ
                     RANFPKLLNRPGFLLTLAHVSGEHVGFGYGHLLPPETRWWKGLQEPLEEEFAIETGART
                     FAIIDFGVLPDWRGRSIGRLVHDELLSRSGAERATLAVRPTATETRAVYRHWGWRKVGH
                     EVMDPPIPSPSFDIMISDSMPKIDG"
     gene            complement(6919..7536)
                     /locus_tag="AW272_RS36450"
     CDS             complement(6919..7536)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888410.1"
                     /locus_tag="AW272_RS36450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavoprotein"
                     /protein_id="WP_245657900.1"
                     /sec_met_domain="Flavoprotein (E-value: 8.9e-12, bitscore:
                     38.3, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDSNRARTGREIDTMPEGKQPVLYVIGCGGRPAGGLPDLVTSLQ
                     SDGWTVCVISTPSGARFVDRALLAELTGYPVRVEYERPEEPPVLPLADAIAVVPATFNT
                     INKWALGISDTLALGLLNEAIGLGLPLVAAPWPNTALARHPAFMPSVERLTTCGVSFVW
                     DVERLPLPNSGEPGAASFPWSELHSEIGRIRTICTNRIGGGR"
     gene            7769..8032
                     /locus_tag="AW272_RS36455"
     CDS             7769..8032
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017620665.1"
                     /locus_tag="AW272_RS36455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_066374727.1"
                     /transl_table=11
                     /translation="MKLKFLGIYPNTPDDGSPTIWLDEDTGDLVIQSYKADEATLRTCQ
                     EVGSVPGHTTDVPEHETVIRLPANMLQFLPRPDSEVHGDSNS"
     gene            8016..8531
                     /locus_tag="AW272_RS36460"
     CDS             8016..8531
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017620666.1"
                     /locus_tag="AW272_RS36460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6879 family protein"
                     /protein_id="WP_245657901.1"
                     /transl_table=11
                     /translation="MTAIREALASARRSAVHLEMRDSYMLDDPAFLAWQRGERSDPNDR
                     ASWWRPWLDVVAEATQRGVVMRRARIISEPIHPYIRYEYDGTFTNIAAGEQVRWLPRRR
                     TTDLLLPGVDFWAFDDELVIFNHFTGAGQWADPGMELCNDFHVAKGCAAAFEAIWDRAI
                     PHDQYQPD"
     gene            8542..9390
                     /locus_tag="AW272_RS36465"
     CDS             8542..9390
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013153405.1"
                     /locus_tag="AW272_RS36465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_066374730.1"
                     /transl_table=11
                     /translation="MRAAASSSVQRARQVLADRLAELRRDANLTGRELAARCGWHASKV
                     SRIENAVTPPSAEDIQLWTAHCGADQQAPDLIASLRVVEGMWVEWRRMERAGLRQAQEA
                     RLPLYERTRNFRSYSSWLIPGMIQTPAYTEAVLRAVQQRRGLVDDVDEAVAARVERQRI
                     LREGDHRFAILVEESVLRAGIGGTAVMASQLEHLHAVSALPNVSLGVVPMRSDRSRWPV
                     EGFWIYDAAQVNVELVSGYLTITQPSEIELYVQAFSELAALAQYGAAARSLIVAARNAL
                     A"
     gene            9610..9780
                     /locus_tag="AW272_RS36470"
     CDS             9610..9780
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017573280.1"
                     /locus_tag="AW272_RS36470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_218011185.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 6.1e-15, bitscore:
                     48.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAAAPTVLDAPKQQGRLDSAAFELDITVIEQADLGGLVRLTDDG
                     CGSTCTACTTG"
     CDS_motif       9610..9723
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MAAAAPTVLDAPKQQGRLDSAAFELDITVIEQADLGGL"
                     /locus_tag="AW272_RS36470_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9724..9780
                     /prepeptide="core"
                     /locus_tag="AW272_RS36470_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-4.30"
                     /molecular_weight="1606.8"
                     /monoisotopic_mass="1605.7"
                     /core_sequence="VRLTDDGCGSTCTACTTG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAAAAPTVLDAPKQQGRLDSAAFELDITVIEQADLGGL"
                     /leader_location="[9609:9723](+)"
                     /alternative_weights="1624.8"
                     /alternative_weights="1642.8"
                     /alternative_weights="1660.9"
     gene            10001..12991
                     /locus_tag="AW272_RS36475"
     CDS             10001..12991
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="AW272_RS36475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_218011186.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 4.3e-193,
                     bitscore: 636.2, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2.2e-18,
                     bitscore: 60.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 7.4e-19, bitscore:
                     61.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWEIGPVAEAISHASPDLARAVQEQYAADPAELDARRVRRSLLSV
                     SRYLLRMTGRPTPFGLVAGVAPAEFGPATVAGATWGDAHRAVAQPAAGWLAEVIDRLEA
                     TPDVLIRLDVTTNSTLTKRGDDVVVPHQPRFDGERAVVPTEVTIRLTSAVQLVVESAQR
                     PIPVAELVAKLQAEAATVSIERITAMVSTLITRRVLITNLHAPSTETNPLDHLVRVLDT
                     AGITDLDEIAELTRCLRDSLHLLGEHNTAPPAGQAEVRQQLVERMRSQSPSTRHPLALD
                     LRLDAEVVLPQQVAADVQQAALVLARLSEYPYGTPSWRDYHRAFYERYGIGALVPLLDL
                     VDPDCGIGLPAGYPGTLIDPPPPHVKERDELLLSLAQTAAIEGQREVQLDEALIAALDV
                     GPTEPRLPSHLEIAVRVNATGRQALQQGKYTLEMVQVSRNVGGLTGRFLPVLDPGTVEE
                     HTAAMTALPAPDEDTLLVQASFPPLDPATAHVTRAPHVLPMVLSLAEHRPAGDGSLTVR
                     DIAVGCDGRRLYLAVPALGHRIEVSALHSLNLRTHTPPVARFMIEVTRAQCALVTGLRW
                     GAASKLPFRPRIRYGRVILAPATWRLLATDLPGPDISAAQWDEELADWRERRRMPAHIR
                     LVVDDHRLTLDLSQPGHRVLLRRHLRVAAHALLTEVVDPLGAGWCADRAHEVIVPLQAT
                     APPPWPRLPVPSPGRVIHRCHGDAPGASTVLYAQLYGDMRRQDTLLADHLPELLASFDV
                     EPHWWFLRYRDADRLDPHLRLRLRLTDPHAFGPAARIVSEWAERLHRAGLLREVRYPTS
                     YTETGRWGSGAALGAAERVFAADSRTVLIQLQQAIRPHRQALIAAHTVAITVAYLGDVA
                     AGMRWLIEHLPAAAPRTAVPRPVFAEAVRIANPHAGWAALRAAPGGAAIVDAWRPREAA
                     LADWHSLLAEPGPDVAGISGDDALRHILHGHYIRAYGIDFDDEPICLYLARAAALAWRA
                     RTGKAAT"
     aSDomain        10340..10618
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AW272_RS36475_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="3.90E-19"
                     /identifier="RREFam001.1"
                     /label="AW272_RS36475"
                     /locus_tag="AW272_RS36475"
                     /protein_end="206"
                     /protein_start="113"
                     /score="60.1"
                     /tool="antismash"
                     /translation="VTTNSTLTKRGDDVVVPHQPRFDGERAVVPTEVTIRLTSAVQLVV
                     ESAQRPIPVAELVAKLQAEAATVSIERITAMVSTLITRRVLITNLHAP"
     gene            12988..14268
                     /locus_tag="AW272_RS36480"
     CDS             12988..14268
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="AW272_RS36480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_066374733.1"
                     /sec_met_domain="LANC_like (E-value: 6.7e-46, bitscore:
                     149.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRDHPVLVVAEAVADHLADPAIADSLAAGRTWWPHHLAHGAAGI
                     VLLHSERAAAGLAPWQRAHDWLAYIARTAATSGTNSHLNYGVPALAFALATVAEQLPGA
                     YQSTLRQLDATVAEDAHNRAADHDRQLAAGHRPLLADFDVVRGVTGLGAYLLYRTPDSP
                     ALAAVLSYLVRLTEPATHAGRTVPGWWTPVGPHGDLDQQFPDGHANVGVAHGIGGPLAL
                     LALAVRAGITVPGHTEAITAICTWLDHWRADTATGPAWPYWVTRDQHDGGAPASHEHPQ
                     RPSWCYGTAGLARAQQLAAIVLGDVDRQRAAERALVLALNDPAQRAATVDASLCHGFGG
                     MAHLATQMAADADLETAAQLRAAAEAMLDAVHPPDTDPEITTAALLHPEGRGPGLLEGA
                     AGVALAVQAPAAAMLPQTGWDACLLIR"
     gene            14298..16373
                     /gene="fxlM"
                     /locus_tag="AW272_RS36485"
     CDS             14298..16373
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR04364.1"
                     /locus_tag="AW272_RS36485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_066374735.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 4.9e-31, bitscore:
                     101.7, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 5e-44, bitscore: 143.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNHLWQQADIATNSETGRQILARLLAPELDRAVQSGLLTGWWYI
                     RKQVWRLRVCTDAAGFATVADQLDKLVVDGQILHWHPNIYEPEIIAFGGSDGIDCAHRL
                     FHVDSHHLLARERTPSPLGQREITAMLCAVLLRAAGLDRYEQGDVWAKVAEERPIDLVD
                     PAVFDEQRRAPLVTAMTRLLSVNPVGLTESDGPLAGYRPWIDAFEETGQALLTLAQRGL
                     LTRGLRAVLAHHIIFHANRAGISVSDLSTMAALAMTGTFGFDAVVLLRPGSPPTFKVSQ
                     MTTVSDQEATPEALRVAMTERLAGDQVIQSPGVRAAFAAVPRHLFVPHVPARDAYADEP
                     VYTKTAGDGAKISAASQPRIVGMMLEQLDLRPGDRVLEAGAGTGYNAALMGHLVGEAGH
                     VTTIDVDADLVDGARQHLAAAEVGNVDVLLADGALGHPDGAPYNRIIATVGAYEVPTAW
                     LDQLAADGRLVVPLRLRGAASRSIAFVRTGEGWRSVDSQLAVFMPLRGLGDDARRIVAL
                     NSERDVTLQVNKDQDVDAGQLADLLDTLAVTVWTGVVFPPMVPYEWLDLWLALRLPNSI
                     MRMNAAEAAIDRKQVDPMFPWGAMATVEGPNLAYLALRPATPVDGQKRYEIGVTGHGPA
                     AVSLADRIAAEATTWDARFRHRAVRFELSDTAPTANPDEGQFVIDRPRHPISVIWE"
     gene            16447..17505
                     /locus_tag="AW272_RS36490"
     CDS             16447..17505
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW272_RS36490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_218011188.1"
                     /transl_table=11
                     /translation="MSARITALAELADRAAQDGDRTTASRVHNQAALIASDCGQPDLAR
                     AWCHRHALAYLAGPVDDSQTARNALEPLVNLARLHTRAGSGDAAVALLDDLYQSVLSRI
                     DTVIDGLTVPAAALTNTADGHRELSRWLWSVQLADGTRALTVAGRWYEAETWLRCHNGI
                     GTRMLDGRQVAIIARATCGEHSDALQLLADTEPGEPWEAAVNACLTTLIRADIQQLRPS
                     DLAGVVSRCRNVQPDATLVVFRTRLALSLIDAIGDLNHPTAQAVAHDIFRAVLDARDGY
                     AARDLLAHHDCISAGTAEQAQDLETVLDQSGLGRPLPTSTIDLLETALSVSEAVITQFA
                     SHRASEPQQPGR"
     gene            complement(17777..18328)
                     /locus_tag="AW272_RS36495"
     CDS             complement(17777..18328)
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012905.4"
                     /locus_tag="AW272_RS36495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAD family hydrolase"
                     /protein_id="WP_066374741.1"
                     /sec_met_domain="HAD_2 (E-value: 5.8e-07, bitscore: 23.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQKTEESRTEPVGAASWLNGIACLVLDYAALTDKDAAINPALGM
                     PPVKAEHAEVVHGLYAAGFRLVLATDSNPGLDRRWGLREAGIDELFAVFLQSGQLGLSK
                     PDGIFYELVTTAAVCRPDRIVTIGHSMIKDCQQPIRYGMYAALIRPLGLEAGEVLPHGA
                     RLIRGLEDLIERTPVSQSAS"
     gene            complement(19025..19657)
                     /locus_tag="AW272_RS36505"
     CDS             complement(19025..19657)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.4"
                     /locus_tag="AW272_RS36505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_066374743.1"
                     /transl_table=11
                     /translation="MPQERRTEAGTGERRRYEAEGSVEGIRRPYEKLSAHPISVRVARA
                     LVRDLLHQWQRPDLVESVELITAELISNALKATADALAAESRNAGESGEPPTVVGLGLY
                     QIRTGIVVEVWDRSRMPPKAVNPTEEEEGGRGLLLVGALSRAWGYRRPLPGGKVVYATV
                     EAGAGADTLRLVTVPKSEQTAATITAYEGSPPAIGTARPCAERAISS"
     misc_feature    complement(19142..19144)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            20126..20677
                     /locus_tag="AW272_RS36510"
     CDS             20126..20677
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019322.4"
                     /locus_tag="AW272_RS36510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="UTRA domain-containing protein"
                     /protein_id="WP_066374745.1"
                     /transl_table=11
                     /translation="MLSAFLIRLGSDRYSPKYRESGLSPFLLECAKQGKTGRFEVLSIE
                     RAVPPAEVSSRLRISATEHSVLVRENIFFADADPVHRVTTYIPWVIAEGTGLLNPDVGH
                     PYGIHGILEERGHIMKRQQEDVGARMPKVDEVGYLQLPPGVPVLDTVHISIDQDGTPYE
                     MTRFVSRSDLAGLSYEMPIE"
     gene            20686..>21096
                     /locus_tag="AW272_RS46185"
                     /pseudo=""
     CDS             20686..>21096
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013088.4"
                     /locus_tag="AW272_RS46185"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="EamA family transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDRVGGANVGRLALLAILWGSNFLWISIALRGLSPAQVAFARLAL
                     GALVLLIVVRVRNLVFPANGTLWFHLTVAALFANAIPYTLFAVAEQSVSSSIAGVINAT
                     TPIWTILFGLFTGYDRAISRLKLAGFGIGFAGT"
     misc_feature    20860..20862
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            21236..21796
                     /locus_tag="AW272_RS45415"
     CDS             21236..21796
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW272_RS45415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_066374747.1"
                     /transl_table=11
                     /translation="MVGDARAISALLSDAVGQAALVLTSPPYGAATHGHVRSSRDSGQP
                     GVRKWNHLYSRDRANLAHQGLPGLLEGFGRILSGCVRLLRPGGVVAVTVRPYRERGELI
                     DLPGQVQQAAGQVGLVLTDRIVCLLCGLGQDRLVNRASFFQLHEARKGWARGLPIHATA
                     HEDLLIFRKAPAGPIQAAPEQNP"
     gene            22096..22356
                     /locus_tag="AW272_RS36520"
     CDS             22096..22356
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017623582.1"
                     /locus_tag="AW272_RS36520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_369408820.1"
                     /transl_table=11
                     /translation="MRTNTRSLPNLPGNLGEAGAEVVDVVTAGRLLGMGRTKAYRLAQD
                     GEFPCRVLRIGGRYVVPVRGVRALLGYADDEPRRGDEHEKG"
     gene            22362..23942
                     /gene="xerC"
                     /locus_tag="AW272_RS36525"
     CDS             22362..23942
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0009037 - tyrosine-based site-specific
                     recombinase activity [Evidence IEA]"
                     /GO_process="GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xerC"
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017622932.1"
                     /locus_tag="AW272_RS36525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tyrosine recombinase XerC"
                     /protein_id="WP_245657902.1"
                     /transl_table=11
                     /translation="MANGTTYKTCTCRDEKGKRLGANCPKLRRPSRGGDRWSSTHGKWA
                     YQLELPPHADGTRRNPLRRTGFDTQEEAEAELDHARGLLALDEDAHVKRRITDLILAVL
                     KNTKKLPDTEEVRRKARTHQDLNRQITVAEWLEEFLARKRRIEATTRNGYAAHVRIYLT
                     PYLGDIRLDRLRVSDVAGMFDAIEEFNDVIAIERASGDPERIKKVRYRRPVGASSMHRI
                     RATLRHALNIAIKQDRLRDFNPAAVVELPAVTRPKPVIWTDERVTRWRADYNARTDLAR
                     RARARVDVIGCYISTPRPSPVMVWTPAQTSTFLTRAERHRLHLLYRLITLRGLRRGEAV
                     GLRWQDVNFAGNTIGVHWQITQLGWQPVQGKPKTDASDRVIAVDAETMRLLKKHRANQA
                     KERLAAGDAWADSGFAFTDELGRPLHPQIATDQFYWIAFEAGLPPVRLHDLRHGAASLM
                     LAAGVEMKIVQETLGHVSSTFTRDTYTSVYPEVAAAAAESTAALLATPSPSVLSHGRRK
                     PSSARRFRH"
     gene            complement(24218..24787)
                     /locus_tag="AW272_RS36530"
     CDS             complement(24218..24787)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017885.4"
                     /locus_tag="AW272_RS36530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="WP_218011189.1"
                     /transl_table=11
                     /translation="MREVVLEERAELGLSPTDPLDPYALADAHGIPVYGIGDLLDHGVS
                     PEAFGHFTLGDAAAWSAALVPLGTARLIVENESHSLARRRSNIAHELGHFLLEHPFDRV
                     ILGEDHKRQFDEKQENEAKFMAGELLIPLAAAARMAFDGWDNTRVAEAYGVSKQFAQMQ
                     MKGQRVRAQRAELKYGFGKSATATSN"
     gene            complement(24818..25195)
                     /locus_tag="AW272_RS36535"
     CDS             complement(24818..25195)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /locus_tag="AW272_RS36535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_066374751.1"
                     /transl_table=11
                     /translation="MSDSPGVNVKALHAALDAARTERDLSWRQLAKEIGVSASTISRMA
                     SGLKPDVTAFAAMTTWLRMPAESFYVDPMRTDDEEPELVASIAPLLRARRDLSENDVAY
                     LEEVIAAAARRFRVEREGREG"
     misc_feature    complement(25274..25289)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.17"
                     /tool="antismash"
     gene            25333..25593
                     /locus_tag="AW272_RS36540"
     CDS             25333..25593
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025808.4"
                     /locus_tag="AW272_RS36540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="multiubiquitin domain-containing protein"
                     /protein_id="WP_066374754.1"
                     /transl_table=11
                     /translation="MSHDDHGRPPVSIIVNTRSHPWREKAITFEQLVELAYPGQPPTDQ
                     DTFTVRYSRGHDGHGAGSLTAGRSVNVKNGMVFDVVRTSRS"
     misc_feature    complement(25962..25977)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.93"
                     /tool="antismash"
     misc_feature    complement(26136..26151)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.19"
                     /tool="antismash"
ORIGIN
        1 gaatcgccgg aagctaggta cttttttcac gccgcgggac atcatgaatt acatcgctaa
       61 tctcatgata gagaataatg ttagggctaa tgcgattgcg gatcccggtg ccggggtcgg
      121 cgccttcagc gaggctgcac ttgatctatg gcctgaagcg gtggttcacg ctgttgatgt
      181 taatctagtt actcttggct tgctggctgc ctcgcctgat tcgtcgcggc agaatagatc
      241 cagcaatctc cgtatctgga ggcaagaatt cctcggatgg ctgcttggag agtgggataa
      301 ggagcctggt cctcggctta tctttggaaa tccaccctat actcgccatc agttgttgaa
      361 tatggaagaa aagcaggctg ctgcggtagc gtcaggaagc ctttctccgt cgggaaggtc
      421 ggggctatct acctactttc ttgcggcatc tctcaattca cttcgccccg atgatagcct
      481 ttgccttctc ttgcccgtta actggctaga ggcagactat gcccgctctg tccgccgtca
      541 cttgtggtac gagaccaaga gatcggtcga cgtgcatttg tttccggaga aaaaggatgt
      601 tttccccggt gcccaggtat cggcaatggt cttgtttgtc ggcccaagaa tgagtagtga
      661 gtccgaccag ccgattagaa tatatgaggt agaagagtcg aatggcgcct tcatggcagg
      721 tgtacccatg gaggagaagc ggattgggga tccgcctaac acgcttatgc cagcagcatt
      781 taggcgtgcc gccggcaact atgcgccgag cgaggaaatg gtcactctgg gcgatgttgc
      841 gaccgttcgg cgaggagtgg ctacggggaa taacaaattt ttcctgctaa caaataagca
      901 agtcgctata ttgcctgaag ggtcatatac tcctgcaatc gcgagactgc gagagatgga
      961 agaggattgt tttacgaagg agctccacga taagcttcaa gaggaaggtg agcgttgttg
     1021 gatgttgcag gtcaagaagg aggatagatc aaacgcggca gtagatgcgc ttctttcgtc
     1081 gggtgaagca gagcttgtgc atacggcgta tctctgcaag acccgacctg tatggtatga
     1141 gctagagaga tttccaaccc ctcatcttgt ccttagcccg atgagtaaaa aagtcttccg
     1201 cgtaatggtt aacgctatcg gagcgatacc tacgaatacg ctttatggca ttcggctctt
     1261 cgatgctgtt gactctgttg agagtcgtcg acaattggcc gagtggcttc ggggccctga
     1321 cggccaggat gcgctaacag cgattgctcg caggcatggc gatgggctcc tcaagctgga
     1381 acctcgggca cttctaggcg ttaagattcc aaaacgcatt cttcgatatt ctgaacagag
     1441 tcatactgat acccgaccca aacctcttcg agtcactttg tggtgagagg agggctggtg
     1501 taattgacac tcctgggatg ctttgggttt gcaggcattc gctcgagcat gaacaggaga
     1561 gaccgatcag agcggcgggg gtaatcctgg cgtcaacaga gacgtaggga tcagggctag
     1621 ggcctccgtc caccgtccac cttgatctac gggaagatag gggctgagag tagctgctcg
     1681 acaccatccc agaattctta tctcatcgcc caacgtaact ctggagcagg cgaccataga
     1741 ccattccgta gggttgctgc gacctacgtc gtattcgttg cgcgtcaggt agaacctgaa
     1801 cgaagacagg agttcttccg ccgtttgggt cttaacctct aatcggcgta tgctcgatcc
     1861 gtccagagtc ggagccgtga tgtcgtagcc aaaatagtca gatataagac taactcgcgt
     1921 gcattccgtc gcgaggtccg gcctgtgcag cgtctcgaac tcgccttgca gttctatcag
     1981 aacaaattct tctccagcag cgccgacatt gctgcgatca actttcctgt tgcgctcggc
     2041 aatcaagcgc tcgatagtcg ccgcaatggt atcttcatcg cgggtggcag tgagacttga
     2101 tagcgctggc atcggcagaa gcttgccgtt ctctaaccga agaaggcctg cggcgatgag
     2161 aaggccttcc cccattgtca gggtggaagg cggaaatgtc ttttgtgtag cggtcgttcg
     2221 atagctgctt cgagcatctt cgtgtgcgtt gccggcgctg tcgatgaact tagcgacctg
     2281 gatggccgca gcaatttgat aacgcgttgg actagctgtc atctaggacg caccgctcgc
     2341 caaatgagtt aatacttctt gcaggtccaa ctcgtcgtcg agctccagcc cgaagtactc
     2401 atcgtctggt agcgccagcg gtacaagtcc gggatcagcc agcatttgtc caagccgaac
     2461 catttttgcc ctgacgcgat tgtggatacg ctcgtcgatg gtgccctctg tggtcagtag
     2521 gtagatccga gtctccgtgt cctcggcaag gccgagacga tggatacggt ctagcgactg
     2581 gagatactga ccagcattga atgttcggtc gatataaata gcatcatggc attcatgatg
     2641 caggctgacg ccctcagcca ttgctgccgg gttggctagc agaaccttgc aatcagagtc
     2701 ccgacggaac cgcgtgagtt ctcgttctcg agtacgtacg ccagggtccg catcgtcggc
     2761 actggggatg cccccgtaga caattgctgg ctttagtccc gcgagttgac gttccaatgc
     2821 aagtaggttc cccggaaagt tcgaccagac aagtgtctta cggttctgtt gggcattgcg
     2881 aaagacgatc ttgcaggctt ctgcaatctt tgggggtatc tcgtactctg agtatgtttc
     2941 gatcatgcga cccagagggc taccaggcgg gattgtcagt ggcgggaaac ggtatgcccg
     3001 ggacgggttt gcgctacttg ccagcaattg cgggctggac gctgcttgaa tgagatacat
     3061 tgtcacctca cccagccgag cgaacatctc ggcgtccctt cggccgaggt cgaccagtcc
     3121 ggcatacctc tggaccatcg cgtcgtaaat gtctttctgg accggcccca tttgtatagg
     3181 ggcgaccggt acaaacgtga cgggcggcaa cctcaagtca gccttcgtgg ttcgcacgta
     3241 gagcggttca atgaaattgt tcaaggcgtt catcgagtcg gttgttggct ctgctacaag
     3301 ggctgcccga ggtgctgact tcgacgccat accgccaggc cagaggatgt caattagagc
     3361 gacgagatcg cggggatggt tgggcgcggg ggtgccagta agaatgtcgc ggcgagcggc
     3421 gagcggagcc aatgcgagta gtccgcggcc ccactcgccc atacttccgc gcttggcccg
     3481 gtgcgcttcg tcgatgacaa gatgaacgct gtggtcaccc atccatgaag ccagatccgg
     3541 aagggcattg cgtagcttct ggtagttcac aatcacaaca tctgggttgt gttcaagggg
     3601 gccagtccag cgtgcggtgg tcaggggtgg gtcgaccact tgaagcgcct cctcttccca
     3661 tgcctcgaag gcagataggg gcgccacaac cagaagtttg tccacgcgtc ccgcgccgcg
     3721 ttcgcccagg tgaagggtgt aggttacggt cgtcttcccc gcaccaggta cagagaagtt
     3781 cgcgccgtgg cgcatgtgcc agagcctgtt tgcatcccgg acttggaatg gccgaagctc
     3841 tcgtgtgagc cggtggccgc ttgcttccca atcgggttca gggcgggggc ggttcttgga
     3901 gtcgagcaga ttggtaacgg cttcttggtc gctcctgagc cgtagaagta gagctctcac
     3961 gtcatcgtct gggacgaggc gtgctcctag tcggcgtaga tgcgcttgga gagtgccagc
     4021 tctactgacc aactggtccg cgccaactag cagtggtcgg ccctggcgag gtagcgaccc
     4081 cgcaatgagg atcgcgatct gggaccaagc tgagtccgag aggttcgttc gtgtgaccgc
     4141 aatggcgcgt ccatcgtcgg ccatacgcat cgtcagcacg ggtgtggcgg tgttcgcagt
     4201 catgagtgcc tggccgtaat ctgctccagc gcttcacgtg cttcatctat ctgaactacg
     4261 aggtcgtcaa ggagtgaggt gaccccttca gcggctttgg cgaattcgac ttggtcttgt
     4321 acgtcgtaaa tcgccttgtt tgcagcgacc agggctgcgt gggccttctc tattagtctc
     4381 gatggtgctt ccaatttttc gccggcgtca atgcgcatgc tgctgtcttt tagaccggca
     4441 tcggtggtgt ccctgagaac cttgaggatt tcgttgccgc tgtgcctact accatccggc
     4501 aactccacta ctcctcgcgg gccggcattt gtggctgcga tcgtgagatt aagcaaggaa
     4561 cgaaccgcgt tcccggcagg cttgtcttct gaggaccgtc cgaagtccag caggtccagg
     4621 ccgtcgcctc cagggtcggt cttcggctcg agtgcaggct tcgtatcggt agccgctgca
     4681 gcgatcttgg tgcctatctc tccgccgtgc gtcagcgcat tcatcagatg cttgttcacc
     4741 catccctggg tggccacgcg cagattatgg actgatccca tatcgagtaa atggagatgg
     4801 agccactcgc ggatgtggtc atctcctgcc tctggtccct cacgctcatc gatcgcctga
     4861 acgcgagtgt ccagttctct ccagttctga agtgctccct tcttgcggcc actgccgaac
     4921 gacttgatcg gtatcggcgg gtcaaccaac actcgtgcac gatccatgag tgcaagcagg
     4981 cggaagcgta gtacgacatc tttcggattc agccgttgac gctttgcgat ttgctgctcg
     5041 gtcatttgac cttcctcatg gagggttcgc agcatcatga gttcgcttac gaggtcgtaa
     5101 tcatccttgt gatcacgctg tttctgaacg actgcctcaa ggtcgtacag ttcgccgggt
     5161 ccggtgtcgg acggcagtac agcgacgcgg atggcgtcgt tacgaagttc accttccgcc
     5221 aacagttccc tcatgagaac gcagcgggtg ttcgcgttga tcaacacccc ggaccgggtg
     5281 atgatgccgg gctcgtcctg accttcctcc ctcagagagc gcttaagctc ttcggcgaat
     5341 ttgtgtgact cgctcacaag ctccgcgatg agcttttggg ctgccgggct ctctgggtcg
     5401 gcggccaccg cttcgcttga agagtggtcg gccagcgcgg gcgcgatccg gaagcttttc
     5461 gcgttgagga tcgggaccga gagcggaagg gttaccaccg gcaggttcgt actcccgcgg
     5521 ctcagcggga aggggcgccg ctcgccgttt tctagctgac catgcgcctc gagagccttc
     5581 aggatgtgct gcctgcgtgc ggcctcagtc atcggccatc ctccacttgt tgtgcatgcc
     5641 acgacacatc cagaaggtta gaggggccca ccgacagaat ccctgtcttt tgtggccatc
     5701 cctggcatca catggcgttt gggtagctca tcggttcttg ccacgcggct tacctgggct
     5761 tctgtgaggc tggcaggtgg aaaagattgc gccctggtgc aggtaggcag gggtaagaat
     5821 gttctacggg tggccctggc tctggtgagt caggcagccg cgccgcatgg gcttgctgtc
     5881 gctacaagtg ccgaatcgca tcatgtattg gatttggaga ggccttaatg ggggttattt
     5941 gttaagcccg aaattattgg atctcccgcc gggtgcttgg gcgccagcga gttccgtcag
     6001 atgctcatcg acgattgccg gaccctgggt agggggtgct aacgcgccgt cgttggttcc
     6061 tgatcttgcg ccgcttgtag cgctcctggt cgacaccgca gcggcgctat ccgcgccggg
     6121 ctcgtgtcgg ctggctggtt agcgcgttcg cggccggtat gagaagtccg gcgtcttcgc
     6181 aggggaggag tgcgtgatcg ggttggagta tcccgtgtcg gcagccagtc cggttgcgct
     6241 tggtcgaccc ggtgaccgag aagggcggac aagcctgggg gtggtggccc ttatccgtcg
     6301 atcttgggca tcgaatccga gatcatgatg tcgaatgacg gtgatgggat cggtgggtcc
     6361 atgacttcat gtccgacctt tcgccagccc cagtgccgat agacagcacg ggtctcggtc
     6421 gctgtcggcc ggacggccag ggtcgcacgc tccgcgcctg acctgctcag aagctcgtcg
     6481 tgcaccaggc ggccgatgct gcgtccgcgc cagtcaggaa gaaccccgaa gtcgatgatc
     6541 gcgaaggttc tcgccccggt ctcaatggcg aactcctctt cgagaggctc ctgtagaccc
     6601 ttccaccacc gggtctcggg cggcagcaga tggccgtagc cgaaccccac gtgctctccg
     6661 ctaacgtgcg cgagcgtcag cagaaagccg ggccgattga gcagctttgg aaagttcgct
     6721 cgttggccgg cgaaccccgc atcgtccgta tggaaaggcg gaagccgaaa aacttgctgg
     6781 taaagcgcac ttaccgtagg gccgaaagga agcgcgaggc ttcctgaaag cgtttgggtt
     6841 gcgatcccgg ctgtcacgtc gctgagcgta ggcggaagct gagtgggtgg cgatagggcc
     6901 tggatcacgc cactcggctc atcggccgcc gccgatccga ttcgtacaga tagtgcggat
     6961 cctgcctatt tcggagtgca gttccgacca ggggaacgaa gctgcgcccg gctcgccaga
     7021 gttgggcagg ggcagtcgct cgacatccca cacgaaggaa actccgcagg tggtcaggcg
     7081 ctccacgctc ggcatgaacg cagggtggcg ggccaacgcg gtgttgggcc agggggccgc
     7141 gaccaaaggc agtccgaggc cgatcgcctc gttcagcagc cccagagcta gggtgtcact
     7201 gattcccagc gcccacttat tgatcgtgtt gaaggtcgcg ggtactacgg ctatggcatc
     7261 ggccagcggc aagaccggag gctcttcggg tcgctcgtat tccacccgta ccggatagcc
     7321 cgtcagttca gcgagaagag cgcgatcgac gaacctcgcg cctgacggcg tgctgatcac
     7381 gcagaccgtc cagccatcgg actgcaacga cgtgaccaga tctgggagcc ctccggccgg
     7441 gcgccctcca cagccgatca catacagaac gggctgtttt ccctcgggca tggtgtcaat
     7501 ctcccggcct gttcgagccc tgttgctgtc gtccatcagt gcggattgtt cgatcgggct
     7561 gcacctcatg gccaagaccg gcttcttacg tctggcagat gatcgacatc gctcgcatga
     7621 gggcgatccg aactccacca gtatcaccgc gcagaaagcg tcctgaccgt catggacata
     7681 tgcctattcc gcgcagtgat tgacgagcca agacgggctc gtcaatcgtc gtgcacatcc
     7741 gtgcaacgca tggcacctgg aggcagccgt gaagctaaag tttctaggga tctaccccaa
     7801 caccccggac gacggctcac cgaccatctg gctggacgaa gacaccgggg acctggtgat
     7861 ccagtcgtac aaggccgacg aggcgacctt gcggacctgc caggaggtcg gatcggtgcc
     7921 tgggcacacg accgacgtcc ccgagcacga gaccgtgatc cgtctcccgg ccaacatgct
     7981 ccagttcctt cctcggcccg acagcgaggt acacggtgac agcaattcgt gaagcgctcg
     8041 cgtcggccag acgttcagcg gtgcacctgg agatgcgcga cagctacatg ctcgacgacc
     8101 ccgcgttcct cgcgtggcag cgtggagaac ggtccgaccc gaacgaccgg gcctcatggt
     8161 ggcggccttg gctggacgtt gtagccgaag ccacccagcg cggcgtggtg atgagacgag
     8221 cgcggatcat ctccgagccg atccacccgt acatccgcta cgagtacgac gggaccttca
     8281 ccaacatcgc cgccggcgag caggtccggt ggctgccgcg tcgacgcacc accgacctgc
     8341 tgctgcccgg cgtggatttc tgggccttcg acgacgaatt ggtgatcttc aaccacttca
     8401 ccggcgccgg gcaatgggca gaccccggaa tggagctgtg caacgacttt cacgtggcga
     8461 agggctgcgc cgcggcgttc gaggccatct gggatcgagc catcccgcac gaccagtacc
     8521 agcccgactg aacctccgtc catgcgcgca gcggcgtcat cgagcgtcca acgggcgcga
     8581 caagttctcg cagaccggct cgccgaacta cgccgcgacg ccaatctcac cgggcgcgaa
     8641 ctggccgccc ggtgcggttg gcacgcctcg aaagtctcgc gcatcgagaa cgcggtaacc
     8701 ccgccatcgg cggaggacat ccagctgtgg actgcccatt gcggcgctga ccagcaggcc
     8761 ccggatctca tcgcgtcgct gcgcgtggtg gagggtatgt gggtcgagtg gcgccggatg
     8821 gagagggccg ggctgcgcca ggcccaggaa gccaggctgc cgctgtacga acgaacgcgt
     8881 aacttccggt catactcctc atggctgata cccggcatga tccagacgcc ggcctatacg
     8941 gaagccgtcc tgcgggccgt ccagcagcgc cgtggccttg tcgacgacgt cgacgaggcg
     9001 gtggccgcac gcgtcgaacg tcagcggata ctccgcgaag gcgatcaccg gttcgccatc
     9061 ttggtggagg agtccgttct ccgcgcaggc atcggcggca ctgcggtgat ggccagccag
     9121 cttgagcacc tccacgcggt cagcgcgctg cccaacgtca gcctcggtgt ggtgcccatg
     9181 cggtcagatc gcagccgctg gccggtcgaa ggtttctgga tctacgacgc tgctcaggtg
     9241 aacgtcgagc tggtgtccgg ctacctgacc atcacccagc cgagcgaaat cgagctctac
     9301 gtccaggcat tcagcgagct ggcagctctg gcgcagtatg gtgccgccgc ccggtctctg
     9361 atcgtcgccg cccgcaacgc gctcgcgtaa atcgccgtgc aacttcatag aagatcgttg
     9421 agcgcgaggt gtcgtcgtcc ctagcgtctg aacaggtggc cgtcatgtgg aggccggcgg
     9481 ggagccgata gccgtcagcg catcggccgg tgacgttggt cgaatctcac gtcgtcggcg
     9541 gcgcggttga tggcccgccg ttctgcacat tccctggcaa ccgtcgcccc taccgaagga
     9601 gtgatcggca tggcagcagc agcaccgacc gtgttggacg caccgaagca gcagggtcgc
     9661 ctcgactcgg cggccttcga gctggacatc accgtgatcg agcaggcgga cctcggcggt
     9721 ctggtccggc tgaccgacga cgggtgcggc agcacttgca cggcctgtac caccggctga
     9781 gctgaacgac ctcgcgtccg ggtgctggtc ggcggcagat gctggccagc accgaatctc
     9841 gcttccggag gtgactgtgc cctcggcatc gttcaaggtc gtaggggccg ctctgttgcg
     9901 agcctgcgcg cacgcgccct tcgctctgcc cgcatggcca gacattgagg aaccgtggac
     9961 aacagcgagc gtccaggccg cgcagacttg gttgcggcag gtgtgggaga tcggcccggt
    10021 tgccgaggcc atcagccatg ccagccccga tctggcccgt gcggtgcaag agcagtatgc
    10081 cgccgacccg gccgaactgg atgcccgccg ggtccgccgc agcctgctct cggtgagtcg
    10141 atacctgctt cgcatgaccg ggcgccccac tccgttcggg cttgtcgctg gcgtcgcccc
    10201 agcagagttc ggcccggcca cagttgcggg agcgacatgg ggcgatgccc accgggcggt
    10261 agctcaaccg gcggccggat ggctggccga ggtcatcgac cggctcgaag ccacccccga
    10321 tgtgctgatc cggctcgatg tgaccacgaa ctccactctg accaaacgcg gtgacgacgt
    10381 ggtcgttccg caccagccac gtttcgacgg tgagcgtgcc gtagttccca ccgaagtgac
    10441 gatcaggctg acctcggcgg tacagctggt ggtcgagtcg gcccaacgcc cgatccctgt
    10501 tgcggaactc gtggcgaagc tccaggccga agccgccacc gtttccatcg agcgaatcac
    10561 cgcgatggtg tccacgctca tcacccgccg ggtgctgatc accaacctgc atgctcccag
    10621 caccgagacg aacccgctcg accatctcgt gcgggtactc gacactgccg gtatcaccga
    10681 tctcgatgag atcgccgaac tcacgcggtg cctgcgtgat tcccttcacc tgctcggcga
    10741 gcacaacacc gcaccgcccg ccggtcaggc cgaggtacgg cagcagctcg tcgaacggat
    10801 gcggtcgcag tccccttcca cacggcaccc cctggctctg gatcttcgcc tggatgccga
    10861 agtcgtcctg ccgcagcagg tcgccgccga tgtgcaacag gctgcgctcg tgctggcccg
    10921 gctcagtgaa tacccctacg gcaccccgtc ctggcgggac taccaccgag ccttctacga
    10981 gcgctacggg atcggggcct tggtcccgct gctggatctc gtcgatcccg actgtggcat
    11041 cgggcttccg gccggatatc ccggaacgct catcgaccct ccaccgccgc acgtgaagga
    11101 acgcgacgag ttgctgctgt cgctcgcgca gaccgccgcg atcgaaggcc aacgagaggt
    11161 ccaactcgac gaggccctga tcgccgcgtt ggacgtcggc cccaccgaac cacgtttgcc
    11221 gtcgcacctc gaaatcgccg tccgggtcaa cgccacgggg cggcaggcat tgcagcaggg
    11281 caagtacacg ctcgagatgg tgcaggtctc ccgcaacgtc ggtgggctga ccggccgctt
    11341 tcttcctgtc ctggaccccg gcaccgtcga ggagcacacc gcggcgatga ccgcgctgcc
    11401 agcccctgac gaggacacct tgctggtcca ggcgtcgttt ccgccgttgg acccggcgac
    11461 cgcgcacgtc acccgagcac cgcatgtcct cccgatggtg ctcagcctcg ccgaacaccg
    11521 cccggcaggc gatgggtcac tcaccgtgcg cgacatagcc gtcgggtgtg acggccgtcg
    11581 gctttacctc gcggtcccgg ctttgggtca ccggatcgaa gtgtcggcgc tgcactcgct
    11641 gaacctgcgg acccacactc cgcctgtggc gcgattcatg atcgaggtca cccgtgctca
    11701 gtgcgcgttg gtcaccggcc tgcgctgggg cgccgcctcc aagctgccat ttcgcccccg
    11761 gatccgctac ggcagggtga tcctggcacc ggcgacttgg cggttgctcg ccacagacct
    11821 accaggtccg gacatctcgg ctgcgcaatg ggacgaggaa ctggctgact ggcgagaacg
    11881 gcgccggatg ccggcgcaca tacgccttgt cgtcgacgac caccggctga cactcgacct
    11941 gagccaacca gggcatcggg tactgctacg tcggcacctg cgagtcgctg cacacgccct
    12001 cctgaccgag gtcgtggacc cgctcggggc aggctggtgt gccgaccgcg cgcacgaagt
    12061 gatcgtgccg ttgcaagcaa ccgctccgcc gccctggcca cggctgcccg taccgtcacc
    12121 aggcagggtc atccaccgtt gtcacggtga tgcacccggc gcgtcaaccg tgctgtacgc
    12181 gcagctctac ggcgacatgc gccgccagga cacgctgctc gctgatcacc tccccgagct
    12241 gctcgcctca ttcgacgtcg agccgcactg gtggttcctg cgctaccggg acgccgaccg
    12301 gctcgacccg cacctacgcc tgcggcttcg gctcaccgat ccgcatgcct tcgggcccgc
    12361 tgcacggatc gtcagtgagt gggcggagcg cctgcaccgg gcagggctgc tgcgcgaagt
    12421 tcgatacccg acctcctaca ccgagaccgg ccggtggggc tccggcgcgg cactcggcgc
    12481 cgccgagcgg gtgttcgccg cagattcgcg caccgtgctc atccagctcc agcaggcaat
    12541 ccggccgcac cggcaggcgc tgatcgccgc acacaccgtc gccatcaccg tcgcctatct
    12601 cggtgacgtg gccgccggaa tgcgttggct catcgagcat ctccccgcag ccgcacctcg
    12661 gacagcagtt ccccggcccg tgttcgctga ggcggtacga atcgccaacc cccacgccgg
    12721 atgggctgcg cttcgtgccg cacctggcgg tgccgcgatc gtcgatgcat ggcggccccg
    12781 agaggcggcg ttggccgact ggcactccct cctcgccgaa cccgggcctg atgtcgccgg
    12841 tatcagcggc gatgacgcgc tacggcacat cctgcacggg cactacatcc gcgcctatgg
    12901 catcgacttc gacgacgagc cgatctgcct gtacctggct cgtgctgccg cgctcgcctg
    12961 gcgggcccga accgggaagg ccgccacgtg aaccgcgacc accccgtact cgtcgtagcc
    13021 gaagctgtcg cggatcacct ggccgatcct gcaatcgctg attcgctggc tgctggccgg
    13081 acctggtggc cacatcacct cgcccacggt gcggccggga tcgtgctgct ccacagtgag
    13141 cgggccgctg ccgggctggc cccatggcaa cgcgcgcacg actggctcgc ttacatcgct
    13201 cggaccgccg ccaccagcgg gacgaacagc cacttgaact acggcgtacc agcgctcgcc
    13261 ttcgcgctcg ccaccgtcgc cgagcagttg cccggcgcct accagtccac gctgcgccag
    13321 ctggacgcca cggtcgccga agacgcccac aatcgagcgg ccgaccacga ccgccagctc
    13381 gccgccggtc accgtcccct cctggcagac tttgacgtcg tccgcggggt gaccggactc
    13441 ggcgcctacc tgctttaccg gacgcccgac agcccggcgc tcgcagcggt gttgtcctac
    13501 ctggtgcggc tcaccgaacc cgctacacac gccgggcgaa ccgtccccgg ctggtggaca
    13561 ccggtcgggc cgcacggcga cctcgaccaa cagttcccgg acggacacgc caacgtcggc
    13621 gtcgctcacg gcatcggcgg accactcgcc ctcctggccc tggcggtccg cgccgggatc
    13681 accgtgcccg gccacacgga ggccatcacc gcgatctgca catggctgga ccactggcgc
    13741 gctgacaccg ccaccggacc ggcctggcct tactgggtca cccgcgacca acacgatggt
    13801 ggcgcacctg cctcccatga gcacccccag cgcccgtcct ggtgctacgg cacggccgga
    13861 ctcgctcgcg cgcagcagct cgctgcgatc gtcctcggcg acgtcgatcg gcaacgggcg
    13921 gcggagcggg cgctggtcct ggccctcaac gatccggctc aacgcgccgc cactgtcgat
    13981 gcctccctat gccatggatt cggtggcatg gcgcatctgg ctacgcagat ggccgccgac
    14041 gctgacctgg aaaccgcagc acaactgcga gccgccgccg aggccatgct cgacgccgtc
    14101 catcctccgg acaccgatcc agagatcacc acggccgcac tgctccaccc cgagggtcgt
    14161 ggcccagggc tcctggaagg cgcggccggt gtcgccctgg ccgtacaggc accagctgcc
    14221 gcgatgctgc cgcagacggg gtgggacgcc tgcctgctca tccgctgatc catcgaccat
    14281 ccgagggaat tgcatcgatg acgaatcacc tctggcagca ggccgacatc gccaccaatt
    14341 ccgaaaccgg ccgtcagatc ctggcccgcc tcctcgcccc cgagctcgac cgtgctgtgc
    14401 agagcgggct gctcaccggc tggtggtaca tccgcaagca ggtgtggcgg ctccgcgtct
    14461 gcactgacgc cgccggcttc gccaccgtcg ccgaccagct cgacaagctc gtcgtcgacg
    14521 ggcagatcct tcactggcac ccgaacatct acgaacccga gatcatcgcc ttcggtggct
    14581 cagacggcat tgactgcgct caccgcctct tccacgtcga cagccaccac ctgctcgccc
    14641 gtgaacgcac cccgtcaccg ctgggccagc gggaaatcac cgccatgctc tgcgctgtcc
    14701 tgctgcgcgc cgcgggactc gaccgctacg aacagggcga cgtgtgggcc aaggtcgccg
    14761 aagaacgacc gatcgacctc gtcgatccgg ccgtgttcga tgagcagcgc cgcgcgcctc
    14821 tggtgacggc catgacgcgg ctgctcagcg tcaacccggt cggactgacc gaatcggacg
    14881 gtccgcttgc cggataccgg ccctggatcg acgcgttcga ggagaccggt caagcgctgc
    14941 tcacgctggc ccaacgtggc ctgctgacgc gcgggctacg cgccgtgctg gcgcaccaca
    15001 tcatctttca cgccaaccgg gccgggatct ccgtgtccga tctatccact atggcggccc
    15061 tcgccatgac cggcaccttc ggcttcgacg ccgtggtgtt gctccggcca gggtcaccac
    15121 cgacctttaa ggtttcccag atgactaccg taagtgatca agaggcaact cccgaggccc
    15181 ttcgcgtcgc gatgaccgag aggctggccg gggaccaggt gatccagagt cctggcgtgc
    15241 gcgccgcgtt cgcagctgtt ccccgccacc tgttcgttcc ccacgttccg gcacgagacg
    15301 cctacgccga cgagccggtc tacaccaaga ccgctggcga cggtgccaag atcagtgcgg
    15361 ccagccagcc ccgcatcgtc ggcatgatgc tcgaacagct cgacctccga cccggtgacc
    15421 gggtgcttga ggccggcgcg ggcaccggtt acaacgccgc cctcatgggg cacctggtcg
    15481 gcgaggccgg acacgtcacc accatcgacg tcgacgccga tctcgtcgac ggcgcccgcc
    15541 agcacctcgc cgcggccgag gtcggcaacg tcgatgtcct cctggcggac ggcgcactcg
    15601 gccacccgga cggcgccccc tacaaccgga tcatcgccac cgtcggcgcc tacgaggtcc
    15661 ccaccgcctg gcttgaccag ctcgccgcag acggccgtct ggtcgtcccg ctccggctgc
    15721 gaggcgccgc atcccgctcc atcgcattcg ttcgcaccgg cgagggatgg cgcagcgtcg
    15781 actcccagct cgccgtcttc atgccgctgc gcgggctcgg ggacgacgcc cggcggatcg
    15841 tggccctcaa ctccgagcgg gacgtgacgc tccaggtcaa caaggaccag gacgttgacg
    15901 ccggccagct cgccgacctg ctcgacactc tggccgtgac cgtgtggacc ggcgtcgtct
    15961 tcccgccgat ggtgccgtac gagtggctcg acctgtggct ggcgctgcgg ctcccgaact
    16021 ccatcatgcg gatgaacgcg gccgaggcgg cgatcgaccg caagcaggtc gatccgatgt
    16081 tcccgtgggg cgcgatggcc accgtcgaag gaccgaacct cgcctacctc gccctgcgtc
    16141 cggccacgcc ggtcgacggg cagaaacggt acgagatcgg cgtcaccggc cacgggcccg
    16201 ccgccgtgtc cctggccgac cgcatcgctg cggaggcaac cacctgggat gctcggttcc
    16261 ggcaccgcgc tgttcgcttc gagctgtccg acaccgcccc gacagccaac ccggacgagg
    16321 gccagttcgt catcgaccgg ccgcgccacc ccatcagcgt catctgggaa tgacgcgatg
    16381 gaccccaccg ggccgatagc acaacgcttt cctctgatcg cccggtcgcg tccaccgtgt
    16441 acagccttgt ccgcgaggat caccgctctc gctgaactcg cggacagggc tgcccaggat
    16501 ggcgaccgga ccaccgcatc acgtgtccac aaccaggccg ccctcatcgc gtcggattgt
    16561 gggcagcccg acctcgcccg tgcctggtgc caccgccacg cactcgccta tctcgccggg
    16621 ccggtcgacg actcccaaac agcccgcaac gctctcgaac ccctggtcaa cctagcccgg
    16681 ctccacactc gcgccggctc cggagatgct gctgtcgctc tgctcgacga cctctaccag
    16741 tctgtcctga gccgaataga cacggtcatc gacggcctga ctgtccctgc ggccgcactt
    16801 accaacaccg ccgacggcca ccgtgaactc agccgctggc tgtggagtgt gcaactggcc
    16861 gacggcactc gtgccctgac cgtcgctggc cgctggtacg aagccgagac ctggctgcgg
    16921 tgccacaacg gcatcggtac gcgaatgctc gacggacgcc aggtcgccat catcgcccgc
    16981 gccacctgcg gcgagcactc cgatgccctg caattgctcg ccgacaccga acctggtgag
    17041 ccgtgggagg ccgccgtgaa cgcctgcctc accacgctga tccgagcgga catccagcag
    17101 ttgcgcccat ctgacctggc tggcgtggtg tcccggtgcc ggaacgtaca gccggacgcc
    17161 acgctggtgg tcttccgtac ccggctggcg ctgtcgctca tcgacgccat cggcgacctc
    17221 aatcatccaa ccgcgcaagc cgtcgcacac gacatattcc gtgccgtcct cgacgcccgc
    17281 gatggctatg ccgcccgtga cctcttggcg caccacgact gcatctcggc aggaactgct
    17341 gaacaggccc aggacctgga gaccgtgcta gaccagagtg gcctcggccg accgctgccc
    17401 acgtcaacga tcgatctgct ggagacggcc ctctccgtca gcgaagccgt catcacacag
    17461 ttcgcatcgc acagagccag cgagcctcaa cagccgggaa ggtgaggtag gtgatccgcc
    17521 ggcatcaccg actgatgtgg tggacgccga tcaactccac agtgtcgtac atgccgttcc
    17581 ctcaggttgg acggcgggga ggggagcatg ctcggccctc cccgccgcca gccgccagac
    17641 ctgccgtccg cgcctgcggg ggctacgcgc aggacggctt cgcccaggcc cacggaacct
    17701 ggggttggtc ggcggcggtt catcggagtg agagttgggt tccgcgtcgg tcttcgctct
    17761 caccgggggg cgctagtcag ctcgcggact ggctgacagg ggtgcgctcg atcagatctt
    17821 ccagtccgcg gatcagccgt gcgccgtgcg ggaggacttc gccggcttcc agcccgaggg
    17881 ggcggataag cgccgcgtac atcccatacc ggattggctg ctggcagtcc ttgatcatgg
    17941 agtgtccgat ggtgacgatc cggtccgggc ggcataccgc agccgtggtg accagttcgt
    18001 agaagatgcc gtccggcttg ctcaatccca gttgccctga ctggaggaat acggcgaata
    18061 gctcgtcgat ccccgcttcc cgcagtcccc atcgccggtc caggccgggg ttgctgtcgg
    18121 tggccagcac cagccggaag cccgccgcgt aaagtccgtg cactacctcg gcgtgttcgg
    18181 ccttgaccgg gggcatccca agcgccgggt tgatggcggc gtctttgtcg gtcagggccg
    18241 catagtcgag taccaggcag gcgatgccgt tcagccacga cgccgctcca acgggttcgg
    18301 tccgcgattc ctccgtcttc tgtgtcatgg cctctctttc tctctgttcg tcgtgactcc
    18361 ggtgagcatc acgaccgcct tgtctctggg ggataggggg ctgcgggttg aaggtcgtca
    18421 acctggacga tgagctgggt cgccaatgcg tatggcagca ggtcggcccg gctgaaagac
    18481 acctccacgt tgtgctcccc tgtgggaacc gcctggtaga ggccagcgcc gcagcgtggg
    18541 ccaggggtgt acatgtcggc caggaccgca gccacatggg accggcctgc tgtgtacacc
    18601 gctgaggaga ttcccaaccg ggggcagctg tccagcgctt cggggatgca ggtcctacag
    18661 gtcgggggtg cgctggtcag gccactcgtc tcgtcgatct cccggaacgc cgtcgcggtc
    18721 atgatccacg gaatgcggcc atcatcgtcc ggcgccggtt ctccgcatac ctggcacagc
    18781 agtctctcca tcgctgccca ctgacgccgt gtattgagta gccgccactg aggcaacccc
    18841 gcccgtgtct gcaaacagcg cgctcgcaac accccgctca ccacatcgcc cctctggctg
    18901 aggcgatagg acaaccggac gcctccgatc gatcgcttca cgaacccgat cggggtggag
    18961 accagctcac cggaatacgc gatcacgaac gggacgcgca gctttggttg caccatcggc
    19021 cacgtcacga cgagatcgcc cgttccgcgc acggtcgcgc ggtaccgatt gcgggtggcg
    19081 atccctcgta ggccgtgatg gtcgccgccg tctgctcgga cttgggcacc gtcactagac
    19141 gtaacgtgtc ggctcccgca cccgcctcca ccgtcgcgta cacgaccttc ccgccgggga
    19201 gcggacgccg gtaaccccag gcccgtgaca gcgcgccaac cagcagcagt ccccggccgc
    19261 cttcctcttc ctctgtgggg ttgaccgcct tcggcggcat gcgggagcgg tcccagacct
    19321 ctacaacgat gccagtccgg atctggtaga ggcccaggcc aaccaccgtc ggcggttcgc
    19381 cggactcccc ggcgttacgg ctttcggcgg ccagggcgtc tgccgtcgcc ttcagagcgt
    19441 tggagatgag ttccgcggtg atgagctcca cgctctccac caggtccggg cgctgccact
    19501 gatggagcag atcccgaacc aaggcgcgcg ccacgcgtac ggagatcggg tgcgcagaca
    19561 gcttttcgta gggccgccga atgccttcga cgctgccctc tgcctcgtac ctacgacgct
    19621 ctccggtgcc ggcctcggtg cgtcgctcct gtggcactcc tggtaagcct gccggtgaag
    19681 aaccatgtcg tccgccgttg tcccgggcga tgtcgtgcac cgtcgggtca ggttgttgct
    19741 tgtgtcgagt agttcggaag ccatccacgg gtcgcacctc ccagagcgcg gtcacagttc
    19801 ggcggccacg cggcagtagc ctgaagattc gtctttcgcg gcagacccgt tatccgcagt
    19861 cgccccgtag gtttcggtga ctcgtttccg tgctggccgg ggagtcctgg cggcgcctcg
    19921 gcgtcgagca gcatgccggg cgccgccagg cgaggagagc gttactccgg ccattggtgc
    19981 cctcctcgag tacggcctgg ctgttccctc cttgccagcc aggtcgtacg tggggacgtg
    20041 gggcgccgca ccgcaccacg tctgggtcac aggttttggg gtgttagtac gccgaaacgg
    20101 atgagtttcg atctcggctt cgcagatgct gtccgcgttt ctcatacgac ttggaagcga
    20161 ccgctactcg cccaaatacc gtgaatccgg gctgtcgcca ttcctgcttg agtgcgcgaa
    20221 gcagggaaag accggccgct tcgaggtgct gagcatcgaa cgagctgttc cgccggcaga
    20281 agtttcttcg cgtctccgga tctccgccac tgaacacagc gttctcgtac gcgaaaacat
    20341 attcttcgcc gatgccgacc cggttcatcg ggtcacgacg tacatcccgt gggtcatagc
    20401 agaggggacc ggccttctca atcccgacgt aggccatccc tatggaatcc acgggattct
    20461 ggaagagcgc ggccacatca tgaaaaggca gcaagaggat gtcggggcgc gaatgccgaa
    20521 ggtcgacgag gttggatacc tgcaactccc tcccggtgtg ccagtgctcg acacggtgca
    20581 tatcagtatc gatcaggatg gtacgcccta tgaaatgaca agatttgtct cgcgctctga
    20641 ccttgctggc ctgtcctatg agatgcctat tgaatgatga agggcatgga tcgagtggga
    20701 ggtgcgaatg tcggccgcct ggcgcttctg gcgatccttt ggggctcaaa cttcctatgg
    20761 atctcgatcg ctctgcgagg actctccccg gcccaggtgg ccttcgctcg actggccctc
    20821 ggtgcactgg tccttttgat cgtggtgcgg gtgcgaaact tagtcttccc tgctaacggc
    20881 accttgtggt ttcacctgac cgtcgcggcg ctattcgcga atgcgattcc atacacgctg
    20941 ttcgcggtgg ctgagcaatc ggtcagttct agtatcgccg gagtgatcaa cgccactacg
    21001 ccgatttgga cgatcctatt tgggctgttc acgggctatg atcgtgcgat ctcccgcttg
    21061 aagctcgcgg gattcggcat cggcttcgcc ggcactgtgg tgatcttctc gccgtggcag
    21121 tccagttctg agattgctag ctggggagga gtcgcggccc tcatctctgc ggcaagctat
    21181 ggagtcagct atgtgtacat gaaccgcttt ctagctggcc gcgaacggca aggttgtggt
    21241 cggagacgcc cgcgccatca gcgcgctgct gtccgatgcg gttgggcagg cggcgttggt
    21301 tctcacctcg ccgccctacg gagccgccac acacggtcac gtgcgctcca gccgcgacag
    21361 cggccagccc ggggtccgca agtggaacca cctctactcg cgggaccggg ccaacttggc
    21421 tcatcaaggt ctgcctggtc tgctggaggg gttcggccgg atcctgtcgg gttgtgtccg
    21481 gctgctgcgg cccggcgggg tggtggcggt caccgtccgc ccctatcggg aacgcggaga
    21541 actcatcgac ctgccgggcc aggtccagca ggccgccgga caggttggtc ttgtcctgac
    21601 cgaccggatc gtgtgcctgc tgtgcgggct gggccaggac cgtctggtga accgggcgtc
    21661 gttcttccag cttcacgagg cccgcaaggg ctgggcgcgg ggtctgccga tccacgccac
    21721 cgcgcacgag gacctgctga tcttccgcaa ggctccggcc ggcccgatcc aagcagcgcc
    21781 agagcagaac ccatagccat tcggggactg actagtccca gggcaatcgg cgttctgacc
    21841 agcggatttt gcttgacggc gggtgtggag gtgggcgtcg ataccgccgc caccgaccgg
    21901 tgccgccacg tgcccagggg gccgctgtac ccgacctacg cgggtccagc gcccgggggt
    21961 gccggacggg ccggtcggtg gcgcagcgcc ccgcacacgc cgccgtcacc gtgaccggcc
    22021 gccctgtcgg ccgcccggcc gatcgaaccc atagacggcc ggtttcgtgt cccaccgctt
    22081 ccgcagaggt gatcagtgag gacgaacacg cgaagcctgc cgaacctccc cggcaatctc
    22141 ggggaggcgg gggccgaggt ggtcgacgtg gtgaccgccg gacgactgct cggcatgggc
    22201 cgtaccaagg cctaccgcct ggcccaagac ggtgagttcc cgtgccgggt cctgcgaatc
    22261 ggcggccggt acgtcgtccc ggtccgtggt gtgcgggcgc tgctcggata cgccgacgac
    22321 gaaccccgtc gcggcgacga gcacgagaag ggatgacctc ggtggccaac ggaaccacct
    22381 acaagacctg cacatgccgc gacgagaaag gaaaacggct cggcgccaac tgcccgaaac
    22441 tccgcagacc gagccgaggc ggagaccgct ggagcagcac ccacggcaaa tgggcctacc
    22501 aactcgaact accgccacac gccgacggca cgcgccgcaa ccccctgcga cggaccggat
    22561 tcgacaccca ggaagaagcc gaagccgaac tcgaccacgc ccgcggcctg ctcgccctgg
    22621 acgaagacgc ccacgtcaaa cgacgcatca ccgacctgat cctggcggtg ctgaagaaca
    22681 ccaagaaact ccccgacacc gaggaggtcc ggcgcaaggc ccgcacgcac caggacctca
    22741 accggcagat caccgtcgcc gaatggctcg aggagttcct ggcccgcaaa cgccggatcg
    22801 aagccaccac ccgaaacggc tacgccgccc acgtccgcat ctacctcacc ccctacctgg
    22861 gggacatccg gctggaccgc ctgcgggtct ccgacgtcgc cgggatgttc gacgcgatcg
    22921 aggagttcaa cgacgtcatc gccatcgagc gggccagcgg cgacccggag cggatcaaga
    22981 aggtgcgcta tcggcggccg gtcggagcct cctcgatgca ccgcatccgc gccactctgc
    23041 ggcacgccct caacatcgcg atcaagcaag accggctgcg ggacttcaac cccgccgccg
    23101 tcgtcgaact cccagccgtc acccggccca aacccgtcat ctggaccgac gaacgggtta
    23161 cccgctggcg agccgactac aacgcccgca ccgacctggc acgccgggca cgagccaggg
    23221 tggacgtgat cggctgctac atatccaccc cgcgcccctc accggtcatg gtgtggacac
    23281 ccgcccagac ctcaaccttc ctgacccgcg ccgaacgcca ccgcctccac ctgctgtacc
    23341 ggctgatcac cctgcgagga cttcgccgag gcgaggcggt gggcctgcgc tggcaggacg
    23401 tcaacttcgc cggcaacacg atcggcgtgc actggcagat cacccaactc ggctggcaac
    23461 ccgtccaggg caaacccaaa accgacgcca gcgaccgcgt catcgccgtc gacgccgaga
    23521 cgatgagact cctcaaaaaa caccgcgcca accaggccaa ggaacgcctg gcggcgggag
    23581 acgcctgggc cgacagcgga ttcgccttca ccgacgaact cggccggccg ctacacccgc
    23641 agatagcaac cgaccagttt tactggatcg ccttcgaagc gggcctcccg ccggtccggc
    23701 tgcacgacct ccgccacggg gccgcctccc tgatgctggc ggcgggcgtc gagatgaaga
    23761 tcgtgcagga gacactcggc catgtctcct cgactttcac tcgcgacacc tataccagcg
    23821 tctacccgga ggtcgcggca gcggcggcgg aatcgacggc agccctcctg gccaccccgt
    23881 ccccgtcagt tctttctcat gggcgacgca aaccgagttc cgcgcgacgc ttcagacact
    23941 gatccggtag tcacgaggtg ctcaagtaag gctgatttcc agatcagcac aggcccgctt
    24001 cgaactcgag gcgggcctat gctgtcttcg gtgggtgggg gtgcatgaag gacatgggtc
    24061 gacgccgata tctcgcctat ttcgaagcgc tctggcccgc tctctgacaa ccgagtcgac
    24121 tgttggactg cgggtctgag ggtggtcggc gctgagtcgg atggctgaga tttgcctcgc
    24181 attgcggact ggctggcccg tcgtagcagg atggagttca gttcgaggta gcggttgccg
    24241 acttgccgaa gccgtatttg agttcggctc gttgcgcccg cacacgctgg cccttcatct
    24301 gcatctgcgc gaactgcttg ctcaccccgt aagcctcggc gacgcgcgtg ttgtcccagc
    24361 cgtcgaaggc catccgcgcg gctgcagcga gtggaatcaa cagctcgccg gccatgaact
    24421 tagcttcgtt ctcctgtttc tcatcgaact ggcgcttgtg gtcctctccg aggatcaccc
    24481 tgtcgaaggg gtgttccagc aagaaatggc cgagttcgtg ggcgatgttc gaccggcgcc
    24541 gggcgaggga gtgggactcg ttctccacga tgagacgtgc cgtgcccagc ggaaccagcg
    24601 cggcggacca cgcggccgca tcaccgaggg tgaagtgacc aaaggcttcc gggctcacac
    24661 cgtgatcgag tagatccccg attccgtaaa cagggatccc atgggcgtcg gccagcgcgt
    24721 acggatcgag tggatctgtc gggctcagcc cgagctctgc ccgctcctcg agcacgacct
    24781 cgcgcatcag cggctgcgtc cacccacctc gggccattta gccctcccgg ccttctcgtt
    24841 cgacccggaa ccgccgggct gcggcggcga tgacctcttc gaggtacgcc acatcgttct
    24901 ctgacagatc acgacgcgcc cgcagcaggg gggcgatgga ggccacgagt tccggctcct
    24961 cgtcgtctgt tcgcatcgga tccacgtaga aggactcggc tggcatccgc agccaggtgg
    25021 tcatcgccgc gaacgccgtg acgtccggct tcaagccgct ggccatgcgg gagatcgtcg
    25081 acgctgacac gccgatctcc ttggccaact gccgccacga taggtccctt tcggtgcgcg
    25141 cggcatccag ggccgcgtgc agcgccttca cgttgacccc agggctgtcg ctcatcccgg
    25201 gtgcccctga cttctaccaa cgctcgatat gtcgctcacc cctgccacag tagcagtgct
    25261 cgaaacttcg agcactggtc tacatctggc gcaggtgtgg accgggctcg ccatgcgcca
    25321 caggagaaac ccatgtctca cgacgaccac gggcgtccgc ccgtctcgat catcgtcaac
    25381 acccgctcgc acccctggcg ggagaaggcc atcactttcg agcagctcgt cgagctcgcc
    25441 tacccgggcc agccgccgac cgaccaggac accttcactg tccggtacag ccgtggccac
    25501 gacgggcacg gagccggaag cctgaccgcc ggccgcagtg tgaacgtcaa gaacggaatg
    25561 gtcttcgatg tcgtccgcac ctctcgttcg tgatccggac ctgtcccgcc tgctcgacga
    25621 cggctatgac gtcgtggtgc aggcggggca cctgctcgtc cggcacattc cctacgtcac
    25681 cgaggccggg accgtccaat acggattcct cgcctacccg gtcaccgtca gcggcgaccg
    25741 ggtcgtctcc gacaccgacc accgcatctg gttcggaggc tcggcaccgt gcgacgagca
    25801 cggccgcagg ctgccgatgg tcaacgacga gttccgggcg attgccgacg gtgtccaggc
    25861 gaacttcatg ctgtcctcca aaccgggccc gaacggctac cccgaccagt acaccaaggt
    25921 caccgcctac acccggatga tcgccgacca ggcacaggca ctggacccga tggtcacggc
    25981 catcccggga gcggcctggc aggaagtcga ggacgactcg cccttcgtct accgcgacac
    26041 tgccacctcg cgggccgggc ttgcgacggt ccaccgtcgc ttccggggcc accacattgc
    26101 gatcatcgga ctcggcggca ccggcgggta catcgtggac caggtcgcca agaccgaggt
    26161 cgagtcgatc ctgctcatcg acggagacca cttcgacaac cacaacgcct tccgcgcacc
    26221 gggcgcggca ccgctggaga cactccgaga acgcccgaac aaggccgcct acttcgcgtc
    26281 ggtctactcc cggatgcacc gcggcatcac gacgcacgag cactacctcg acgaggacaa
    26341 cctcgaagtc ctgtctgggg tcaccttcgt gtt
//
