LOCUS       NZ_BBXD01000008        22550 bp    DNA     linear   CON 08-AUG-2024
DEFINITION  Herbidospora mongoliensis strain NBRC 105882, whole genome shotgun
            sequence.
ACCESSION   NZ_BBXD01000008
VERSION     NZ_BBXD01000008.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Herbidospora mongoliensis
  ORGANISM  Herbidospora mongoliensis
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Herbidospora.
REFERENCE   1
  AUTHORS   Komaki,H., Ichikawa,N., Oguchi,A., Hamada,M., Tamura,T. and
            Fujita,N.
  TITLE     Genome-based analysis of non-ribosomal peptide synthetase and type-I
            polyketide synthase gene clusters in all type strains of the genus
            Herbidospora
  JOURNAL   BMC Res Notes 8, 548 (2015)
   PUBMED   26452464
  REMARK    DOI:10.1186/s13104-015-1526-9 Publication Status: Online-Only
REFERENCE   2  (bases 1 to 910721)
  AUTHORS   Hosoyama,A., Oguchi,A., Ichikawa,N., Kimura,A., Ohshita,R. and
            Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-MAY-2015) Contact:Director-General Department Of
            Biotechnology National Institute of Technology and Evaluation,
            Biological Resource Center (NBRC); 2-49-10 Nishihara, Shibuya-ku,
            Tokyo 151-0066, Japan URL :http://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Noncontiguous Finished
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: newbler v. 2.6
            Genome Coverage                   :: 62x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001570545.1-RS_2024_08_08
            Annotation Date                   :: 08/08/2024 02:40:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,280
            CDSs (total)                      :: 8,202
            Genes (coding)                    :: 8,113
            CDSs (with protein)               :: 8,113
            Genes (RNA)                       :: 78
            rRNAs                             :: 4, 6, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 4, 5 (5S, 16S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 21 of 89
            Pseudo Genes (incomplete)         :: 71 of 89
            Pseudo Genes (internal stop)      :: 4 of 89
            Pseudo Genes (multiple problems)  :: 7 of 89
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:23:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 866980
            Orig. end                         :: 889530
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBXD01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22550
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="2"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22550
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22550
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12550](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12550
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    complement(432..447)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.02"
                     /tool="antismash"
     gene            complement(1691..2566)
                     /locus_tag="AW272_RS04320"
     CDS             complement(1691..2566)
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546783.1"
                     /locus_tag="AW272_RS04320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar kinase"
                     /protein_id="WP_066361113.1"
                     /transl_table=11
                     /translation="MTDLFTLGEVLGVVTADRIRHDMSARLDLEGPELTVAVGLARLGH
                     SVAYVGRVSDDEVGIRTSTVLRGEGVDVSHVKVDETAASGLALRQRRIGRVAHAVFYRE
                     GSAGSRLSTGDVPTAVQDARILHVTGITPALSGYAWSAVHHAVKLAKDAGVLVSVDVNH
                     RATLWDSVNEARQGLRELAGSADILFANQDELDLVEPALAQVPELVVTRGSKGASATVE
                     GFRYDTQAAPVTVVDATEVGGAFVAGYLSAVLDGVHPSDRLKRGIAVAAFAVASHSTWQ
                     GLPNRSELPP"
     misc_feature    2541..2556
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     gene            complement(2684..3112)
                     /locus_tag="AW272_RS04325"
     CDS             complement(2684..3112)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW272_RS04325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157518290.1"
                     /transl_table=11
                     /translation="MVLLGLLLIVLAGAVLIEISVQETTATATTPISVLDWNFTLTSFE
                     MFLLGVGTAAGVLIGLAMVSGGMRRGVARRRRLREERLAERDRVSRLESEKRNLEQKLV
                     DQNHNGVDDRDETRPVEHAEDGDQLVAGGRHSRRDDAF"
     misc_feature    complement(3159..3174)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.58"
                     /tool="antismash"
     misc_feature    3161..3174
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.87"
                     /tool="antismash"
     misc_feature    3231..3240
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.82"
                     /tool="antismash"
     gene            3237..3440
                     /locus_tag="AW272_RS04330"
     CDS             3237..3440
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW272_RS04330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_066361115.1"
                     /transl_table=11
                     /translation="MSELQQVEEEIARIRAEARSLREQIGDRAGEGPADSAELSSLIAG
                     ADQLDTLAEELEGRRETLKNQG"
     misc_feature    3645..3665
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.25"
                     /tool="antismash"
     gene            3890..5197
                     /locus_tag="AW272_RS04335"
     CDS             3890..5197
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131099.1"
                     /locus_tag="AW272_RS04335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_066361116.1"
                     /transl_table=11
                     /translation="MSHPPRRRAARLLVPLIAASLLAACGGGENTPAPGATGSAPAPAA
                     AEPVKLTVALFSDFHYGPLYEEFKKTHPNVEITERRAQFNDHHNNLVTQVATGAGAADI
                     VAVEGGFIATFREVADKFHNLNDFGLQSRQAEYLDWKWQLGLSKDGSQLIGLGTDVGGL
                     AMCYRPDLFKAAGLPSNRDEVGALWPTWEQYVETGKKFVAAGGKAAFTDGPGEHFRAMV
                     EQAPVGFYDTSDKVVVGSNPDVRKAWDVSVSMIQNKLSGKLVAFTPEWTTGIAKGTFAT
                     MVCPAWKTGVIKDQKPGEGTWDIAAVPGGGGNQGGTHLLAPKQGKHPKEAAELINFLTS
                     KESQLTLWKDASALPSLPGLYTDPAVADFVNPYFGDAPIGKIFTDAAKALKPQYTGPKS
                     GDVNVAMGNGLGRIELQGQDPEESWKQAVSDSEKIK"
     misc_feature    4319..4321
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5254..6219
                     /locus_tag="AW272_RS04340"
     CDS             5254..6219
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893596.1"
                     /locus_tag="AW272_RS04340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_066361117.1"
                     /transl_table=11
                     /translation="MATRAPERAAPPRRPGGKRRLNARHWRHAVDVKASPYAYVAPFFL
                     LFCAFGLFPIGYTLWVSLHEWTLLKDEHTFVGLENFRVLLTDSYFWNATYNTLSIGVLS
                     MVPQLLLALWLAHLLNRPLRAQNFFRITLLLPNVTSVVAVVVIFSQIFGRDFGLINWVI
                     TSFGFEGVAWRDGTLSSHLAISTMIMWRWTGYNALILLAAMQAVPRELYEAATIDGASS
                     STQLRKITVPMIRPTIAFVVITSTIGSMQIFAEPLLFGAYTLTGGQDRQYQTLSLFFYE
                     NYMRLDFGFSSAISWMIFIFILIIAGINFLLTNRMKGSVR"
     gene            6216..7040
                     /locus_tag="AW272_RS04345"
     CDS             6216..7040
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131097.1"
                     /locus_tag="AW272_RS04345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_066361118.1"
                     /transl_table=11
                     /translation="MNGRRVGNRLTYLTLTAVAFFFTIPLYYSIVVASRDNASLASVPP
                     PLFPGGNFFENVSRVFDTVPFGLAMLNSVFVAGLISISVMFFSTLAGFAFAKLPFRGRN
                     ILLLMTVGTMMVPTLAGIIPLYILMVKLEWVGSLYAVIVPALVNAFGVFFMTQYLSRAL
                     PTELLEAGRVDGCTTWGLVWHVVFPAARPAAAVLGMLTFMTAWNDYLWPLMVLTPENPT
                     VQVALSTLAAGYVNDYVMGLAGTALGTLPLVIVFAFLGKHIIGGIMQGAVKG"
     gene            7037..8410
                     /locus_tag="AW272_RS41765"
     CDS             7037..8410
                     /EC_number="3.2.1.21"
                     /GO_function="GO:0008422 - beta-glucosidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030245 - cellulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889988.1"
                     /locus_tag="AW272_RS41765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GH1 family beta-glucosidase"
                     /protein_id="WP_066361119.1"
                     /transl_table=11
                     /translation="MTPDIEFPEGFIWGAATASYQVEGAAREDGRGVSIWDTFARTPGK
                     VADGHTGDVACDHYHRYPDDVRLMADLGLSVYRFSTAWPRVVPDGSGPANPRGLDFYDR
                     LVDSLLDAGITPYVTLYHWDLPQNLEDRGGWTSRDTAYYFADYAAAVHARLSDRVSNWT
                     TLNEPWVCAFLGYGSGVHAPGVTDAASAFKAAHHQLLGHGLAAQNLTGTLTLTLNMAPV
                     VTPAQIVDVAHVLTDDDAEAIRRVDALLNRQFLDPALKGTYPAEVLDIAAEHGGLDHIR
                     DGDLEIIRQPIDLLGINYYNPCVIQAAAGAVAPPAWPGTDGIEFVTIEGPQTAMGWPVI
                     PSGLSRLLVRLSHDYPDVGLIITENGAAFHDKVVGDRVPDSDRVAYLDGHLRACHQAIA
                     EGADLRGYLVWSLFDNFEWAEGYHQRFGIVRIDYATQRRLPKDSALWYRDVIQRNGIE"
     gene            8407..9402
                     /locus_tag="AW272_RS41770"
     CDS             8407..9402
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131095.1"
                     /locus_tag="AW272_RS41770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_066361120.1"
                     /transl_table=11
                     /translation="MKRPTLEAVAARAGVSKSTVSRVVNGDTTVTPNFRELVLRAVNEL
                     GYVPNSVARSLVTQRTNSIALIVSDPPAGLFSDDPMFSTVVRSASRALEAASKQVVLML
                     AGSDESRVRVQEYIAAGHVDGVMLVSFYGADPLPAALMRMGLPMASFGKPVSAPSVPYV
                     DNDNLGGARQAVEHLLSRGRRRIATISGPLDMIASQDRLTGYRETLRDTGRRSIIAVGD
                     FTRVSGDQAMCQLLEDDPGLDAVFAANDLMAIGALHALRRAGRRVPEDVSVVGFDDIEA
                     ALYTDPPLTTVRSPMADQALAVVSLLLGLFEDGDIDPVILPTELMVRESG"
     misc_feature    9157..9159
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(9421..9834)
                     /locus_tag="AW272_RS04360"
     CDS             complement(9421..9834)
                     /GO_function="GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653514.1"
                     /locus_tag="AW272_RS04360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CoA-binding protein"
                     /protein_id="WP_066361121.1"
                     /transl_table=11
                     /translation="MGDRFADLTAIRRLLNDTTTWAFVGLSGDPGRTVYNQAKLMKNRG
                     KRIIPVHPDGRPVLGETTYRTLADVPVPIDVVAIYRRTVFAGDVIDEAVKVGAGAVWLP
                     LDVYDEAAGDRALAAGLDVIMNRCPAVEWALRR"
     misc_feature    complement(9833..9849)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.35"
                     /tool="antismash"
     misc_feature    9934..9947
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.0"
                     /tool="antismash"
     gene            10001..12550
                     /gene="lanKC"
                     /locus_tag="AW272_RS04365"
     CDS             10001..12550
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017559021.1"
                     /locus_tag="AW272_RS04365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_083957933.1"
                     /sec_met_domain="micKC (E-value: 2.6e-217, bitscore: 719.5,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 5.8e-16, bitscore: 54.4,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 1.3e-06, bitscore: 24.4,
                     seeds: 156, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3e-06, bitscore: 22.0,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDQYELYCLADRLFYDAPDRRGTDIPDFAVAGRDVPRGWSHQPS
                     DTWFHYAPTGHDVPPQGWKIHVSAGLADAARVLEIVWDYCVERDIPFKFLRSRSVVTML
                     NSKGASRGSSGKLVTIYPRQDCLELTLKELDGLLTGVRGPYILSDLRYGDGPLFVRYGG
                     FVARRCAAPNGELVPAMENDRGELVPDVRGASFTTPEWVTLPDFLRAHLEARNAVTTGE
                     LPYSVDSVMHFSNGGGVYLATDRRTDERVVLKEARPMAGLDAAERDAVARLQHERDVLR
                     RLDGLDCAPGYRDYFVLGDHHFLVMEFVDATPLQRTLVRTFPLSKADATAESIAEYTVW
                     ALDTLPKVRAAVEALHERGVVFCDLHPNNILITPDGRLVLIDFEVATFIEDRGRSVLAH
                     PAFQAPADRRGADVDLYALACLTLGLFAPQLTITVPLARAKATQLGHMIVDTFPVPPEL
                     IKRAVHTITGPIGGGPTASVTSGDPMAAMARGILASATPRRSDRLFPGDVAQFHPGGGI
                     NLAHGAAGVLLALDAAGAGRFPDYEEWLLRRTQDSRTQDLQAQDRQNLECPPGFYDGLH
                     GVAYVLDRFGHVDQALDLVDRAMSGPWRELDLSLYSGLAGIGLNLLHLGLDARPLVELC
                     AERLPDDVPEISGGSHPRAGLLYGLSGPALLFLRAYDHTRDPALLDLAERALRLDLKRC
                     VVTADGSLQVDQGWRTLPYLDEGSAGIAIVLGDLLRRRPGSSLAAALPDLLKVGRCRFF
                     VQPGLFAGRAGMILADRTLVPGLDWHVLPYRDGIAFPGDQLLRLSMDFATGTAGVLFAL
                     SGTPLPFMHPLGAEPYAMPGGAPLQLSTKEVIGARNS"
     misc_feature    complement(12556..12569)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.75"
                     /tool="antismash"
     misc_feature    complement(12591..12605)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.38"
                     /tool="antismash"
     gene            12614..12763
                     /locus_tag="AW272_RS41775"
     CDS             12614..12763
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012892884.1"
                     /locus_tag="AW272_RS41775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_157518294.1"
                     /transl_table=11
                     /translation="MVLLDLQAMELPGGGGGHGGGGGGGGGSTLTLLGCASQTPSNLSL
                     LLCH"
     CDS_motif       12614..12667
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVLLDLQAMELPGGGGGH"
                     /locus_tag="AW272_RS41775_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12668..12763
                     /prepeptide="core"
                     /locus_tag="AW272_RS41775_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="7.00"
                     /molecular_weight="2660.0"
                     /monoisotopic_mass="2658.4"
                     /core_sequence="GGGGGGGGGSTLTLLGCASQTPSNLSLLLCH"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVLLDLQAMELPGGGGGH"
                     /leader_location="[12613:12667](+)"
                     /alternative_weights="2678.0"
                     /alternative_weights="2696.0"
                     /alternative_weights="2714.0"
                     /alternative_weights="2732.0"
                     /alternative_weights="2750.1"
     gene            12852..14453
                     /locus_tag="AW272_RS04370"
     CDS             12852..14453
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653863.1"
                     /locus_tag="AW272_RS04370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_066361123.1"
                     /transl_table=11
                     /translation="MRTADRLTTEAIRRSGPAAGVLVAVSLVGAGLELALPFVLGRAVD
                     TFSLTWVISAGAVVVLLVVCDGLGVYASGTGGARAAAWLRHRALSHLLGVGPGVTRRIP
                     AGDLVTRLGVNAEEAGRAGDAVVASVALVVPSAGALVLLVLIDPWLALTLAGGLVVIVF
                     VLTRFLKTSTTIAGRYQEAQADIAARLVEAVAGARTIAAAGTAERETRRVLTALPVVRG
                     HAMALWRANADAGVRAAIVVPLLEVLVLAVGGWRLSAGELTVGELYAAARYVVIGAGLG
                     PAIGSLGRLARARAAGARLAEILDECPVAHGVRELPPGPGTLTFRDIWPDDLEIQGGTS
                     VAVVGSGASRFARLAARLDDPAVGDVLLDGVPLRSLTRRSLRSAIGYAVAKPHLIGDTV
                     AEATGDSREAAVAAGADDFIRRLPHGYRTPPAEAPMSGGERQRLGLTRAFAKGNRLLVL
                     DDATSSLDTITERRVGTALAADTRTQVMVTHRAAVAARADRVIWLDQGRVRGFDRHLAL
                     WRDPDYRAVFQGGEAQ"
     misc_feature    14400..14402
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14497..16140
                     /locus_tag="AW272_RS04375"
     CDS             14497..16140
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653862.1"
                     /locus_tag="AW272_RS04375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_083957935.1"
                     /transl_table=11
                     /translation="MISFGHRTRVGSFLWRSFNAQPGQAWRFVLWSLVEAAPAFVIGLA
                     IARAVDAFTAHQAVAGLSWTFLLGISWIFAAVGARQVVVTLAGIVEPVREELLTATVRG
                     ALEAGRNDAAAVTRANLQVEVARDAFTGVIGSVKAFVFAFLGVVAGVMALMPELLLLVL
                     PPLLLALGAFLFSLPELAKRQHAYLLADEATAESLVRVTAALGDVAASGDEEHAARYAG
                     SRFDDQRRAAGKLAGVTTLRTVVLGTGAWAPILLVLVYAPRLGASPGVVLGTLAYVMQS
                     LTPALFNLASGLGESGVRLWVTLTRLRAALPPPPQETHRSEGVHTELKGVTFAYGPQAL
                     PVVDRLDLVVPEGEHLAVVGPSGIGKSTLAALIAGLVVPGQGRVTVGGVPAVRLHKGQR
                     VLIPQEAYIFRGTVAENLGDHQPARMRQALDAIGAGHIRLQVTELGPADRQLVALARAF
                     LADAPLVILDEATSCLDPAAEAQVERAFAETGCTLIVIAHRISSALRARRVLVMDGTRI
                     VTGTHQELLAASPLYADLAGHWDPRLRQVS"
     gene            16137..18023
                     /locus_tag="AW272_RS04380"
     CDS             16137..18023
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630269.1"
                     /locus_tag="AW272_RS04380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prolyl oligopeptidase family protein"
                     /protein_id="WP_066361124.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 2.8e-50, bitscore:
                     166.5, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEIIHGHVVSDPYRWLEDPASDETRAWQAQQEVVWQSQLLPGRD
                     GFLARIEELSDTGVVGAPVWRAGTAFRVRRDPGRRLPVLYADDRPILDPEAIDPGATTL
                     LDAWHPSPDGELVACQLSRGGDERSELYVISARTGALVDGPVGGLRYSPVAWLPDSDGF
                     YYVRDRRARVHHLGGDDLDVADADGIALSADGRWLTLSVNRGPGNDVWLCDLVSPARWT
                     VQQDVAARSAVAVGRDGRAYMVTTLDAPRGRLRVADPAVPHEFRDLVPEDAEAVIADFV
                     LLDGVLLVAWVRHAIGEISVHDPETGERQGAVPLPGLGSIGRMSARGHEVWFTYSDYVT
                     PESVYRYDARTGETTLWEAAPGRAELPEIESHQVVYQSADGTPVRMVVLGRGLPGPSPC
                     ILYGYGGFGVPLTPSYSSYVLPWLEAGGVFAFAQVRGGGEEGEGWHRAGMRGRKQNSFD
                     DFAAAAETLIASGWTRPDLLGVTGESGGGLLVGALVTQRPELVAAAVCSAPVLDMIRFE
                     KSGLGSSWVPEYGSADDPEQFSWLLAYSPYHQVKEGVDYPATLFTVFDGDSRVDPLHAR
                     KMCAALQGATSGVRPILFRHEAGVGHAGRSADRAAGLAADMLAFLARELGGL"
     gene            complement(18020..18508)
                     /locus_tag="AW272_RS04385"
     CDS             complement(18020..18508)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889839.1"
                     /locus_tag="AW272_RS04385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_083957937.1"
                     /transl_table=11
                     /translation="MNGSGNVTTLDSIDTTITTDLRAARVARLAGGRDQIVLARRMVSA
                     TIGRDHPLHDDCVLLTSEIATNAVIHSRSGDGGVFTVTVWFSSEEVRVCVQDDGSTEPP
                     CAGHSTATATNGRGLPLLDALADRWGIVREGGRNKVWFEMSLTTAPPSALALFLPRSA"
     misc_feature    complement(18134..18136)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18622..19425
                     /locus_tag="AW272_RS04390"
     CDS             18622..19425
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540024.1"
                     /locus_tag="AW272_RS04390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PIG-L family deacetylase"
                     /protein_id="WP_066361125.1"
                     /sec_met_domain="PIG-L (E-value: 1.1e-28, bitscore: 96.4,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTLMAVHAHPDDEVMGTGGVFAKYAAEGVRTVLVTCTNGEQGDG
                     AGGVKPGDPGHSEADVANQRLAELAESVGHLKIGHLELLGYHDSGMVGWAGNASPDAFT
                     NADFDKAVAKVAALMEEYRPQVVVTYDENGNYGHPDHIQAHRVAVAAAEATGIPVKFYY
                     TAIPRRIIQASYAAMKEQGKDPGWELPEDFGTPDELITSVVDTHEQADAKIAALRAHAS
                     QGDSIALLSMPPEMQRMAMSTEHFIRVSTKVTAPDHEDDLFAGLR"
     gene            complement(19426..20613)
                     /locus_tag="AW272_RS04395"
     CDS             complement(19426..20613)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541059.1"
                     /locus_tag="AW272_RS04395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_066361126.1"
                     /transl_table=11
                     /translation="MGLPDPIRTIEAVWRIESAKVIATVARMTGDIGLAEESAQDAFLL
                     AVETWPHEGVPENPGGWLTTTAKRKAIDQLRRQGVYEEKLRELAQQPPARPEPELLTLI
                     FTACHPDVAVEGRLALTLRLLGGLTTAEIARAFLVPEPTVGQRIYRAKAALRKVPIELP
                     PAEELPARLASVLEVIYLIFNEGYSATSGDSWTRNDLCFEALRLSRVLAALMPTSSEAS
                     GLQALLEIQSSRLNARIGPGGEPVLLADQDRTRWDRLLIRRGLEALTRAESTGVLGPYG
                     LQAAIAAVHARAGVFADTDWARMAALYQLLAHVAPSPIVELNRAVAVGMAEGPEAGLKI
                     VDGLPLEGNPHLSAVRGDLLERSGRVEEARAAFLKAAELTRNVQEKALYEQRARA"
     misc_feature    complement(19681..19683)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(20635..20982)
                     /locus_tag="AW272_RS04400"
     CDS             complement(20635..20982)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540948.1"
                     /locus_tag="AW272_RS04400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YciI family protein"
                     /protein_id="WP_066361127.1"
                     /transl_table=11
                     /translation="MRYLITLTRTAQPETPPPAELMSAIMQLGREATESGALVDQSGLL
                     AKTAEVEVVGGKLTVTDGPFAEAKELISYAIYEVRDEAEAIEWANRFMRLHRDMWPGWE
                     GVSQVHPLMTF"
     misc_feature    complement(21751..21766)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.08"
                     /tool="antismash"
ORIGIN
        1 atacgtcgtg accgaatcga ccggtgtttc ggacgacatg ccgaccgtgc gagatcccga
       61 caacatcgtc tacttccgcg aggagggcgg cggcatcctg gtcggcggct acgtccgcac
      121 gccgcaggtc tgggacgagc ccgacccgct tcgggagtcc cgtttcctgt tcgaaccgga
      181 catgccgaag ttcgaggagt cgtgggcctc cgccgtgaaa cgccttccgc atctgcggga
      241 acgcggggag atcgtcaagg tcgtccacgg gcccgaggcg ttcacgcccg acggggagtt
      301 cctgctgggg gagacctcgg tacgcggcct ctgggtcgcc gccggtttct gcgtgcacgg
      361 cctggccgcc gccgggggcg tgggcaaggt gacggctgag tggatcgtcg acggcgcccc
      421 cgaatacgac atgttcgcca tggacgtctc acgcttcggg ccgcacgccc ggtctcaggc
      481 gtgggcgcgg acgaaggtgc tggattcgta cagcgtctat tacgacatcg tctatccggg
      541 ccaggagcgc caggcggccc gcccgctgcg gcgttccccg gcctacgccc ggcacgccga
      601 gctgggcgcc gagttcggcg agaaggccgg ctgggagcgg gtcaactggt acgccgcccg
      661 tagatggggc tcgccgcgcc cgaacgggtg ggccgggcgg atctggtcac ccgccgtccg
      721 cgaagaatgc ctggccaccc gggacgcggc cgggctgttc gaccagacct cgttctccaa
      781 gttcgacctg cgcgggttcg agcgactgca ggcgctggcc gggaacaacc tcgatcgtcc
      841 cgtcggtacg gtcgtctaca cccagcttct caacaagcgc ggcggcatcg acgccgacgt
      901 caccatcacc cgcctcggcg acgaccggtt ccggctcgtg acgggcaccg ccttcggcgg
      961 ccacgacgcg gcgctgctcc ggaggaacgg ggtcgaggtc accgacgtca cctcggccta
     1021 cgcctgctac tgcctgtggg gccctgcctc ccacgacatc ctgagcgggc tgaccggtga
     1081 cgacctgagc ttcggctaca tgcagtcgcg cccgatcagc gtgggttacg tgccggtcca
     1141 ggcccagcgg gtgaccttcg tcggtgaata cggctgggag ctctacacgc cggtcgagtt
     1201 cgggctgacc ctgtgggaca cgctgatgga ggccggggcg tcgttcgggc tgcggcccgg
     1261 cggttacaag gcgatcgagt cgatgcgtct ggagaagggc taccgggtct ggggctccga
     1321 catcacgccc gagacgactc cgttcgaggc cggtctgggc ttcgcggtcc gccgggaagt
     1381 tccacgcacg gaatccgccg tggaactcgc ctgtctcctc gtcgacgacc ccgccgaggt
     1441 ctgcctgggc ggagaaccgg tgcgggtcga cggggtgccg gcctcgcggg tcacctcggg
     1501 cggttacggc caccgtgtcg acaggtcgat cgcctacgcc tacctgccca agggcgtgac
     1561 cagggtcgag gtcggcgtca acggcggctg ggtgggggcc gacgtgatca ccggcccggt
     1621 ctacgatccg gcgaacctca gggtcagatc agcgggactt tgagctggtg cccgccgtgc
     1681 cgacgccgga tcacgggggc agctctgacc ggttgggcag gccctgccag gtcgagtggc
     1741 tggccaccgc gaacgccgcc accgcgatgc cccgcttgag ccggtcggac gggtgcaccc
     1801 cgtcgagcac cgcgctcaga tatccggcca cgaacgcgcc gccgacctcg gtcgcgtcca
     1861 cgaccgtcac gggggcggcc tgggtgtcgt accggaaacc ctcgaccgtc gcgctcgcgc
     1921 ccttggaccc gcgcgtcacc acgagttcgg gcacctgggc gagcgcgggc tcgaccaggt
     1981 cgagttcgtc ttggttcgcg aacaggatgt cggccgaccc ggcgagttcg cgcaggccct
     2041 gacgggcctc gttcacgctg tcccacagcg tcgcgcggtg gttcacgtcg acggagacga
     2101 gcaccccggc gtccttggcc agcttgaccg cgtggtgcac cgcgctccac gcgtagccgc
     2161 tcagcgctgg ggtgatcccg gtgacgtgga ggatgcgggc gtcctggacc gccgtcggca
     2221 cgtccccggt cgacagccgg gacccggccg agccctcgcg gtagaagacg gcgtgcgcga
     2281 cccggccgat ccggcgctgg cgcagcgcca ggccgctggc ggcggtctcg tcgaccttca
     2341 cgtgggagac gtccacaccc tcgccgcgta ggaccgtgga ggtgcggatc ccgacctcgt
     2401 cgtcgctgac ccggccgacg taggccaccg agtgcccgag ccgggcaagg ccgaccgcca
     2461 cggtcagttc cgggccctcc aggtcgagcc gggcggacat gtcgtgacgg atgcggtcgg
     2521 cggtcacgac gcccagcacc tcgccgagcg tgaacaggtc ggtcattgca ctcttctccg
     2581 cgcgtactga tcggggaaaa gcatgacaga acggtccaat ccggggaatg gtctcggccc
     2641 ccgcctatgg gacgaggcga gggccgatgt tctgggtcag cggtcagaag gcgtcgtctc
     2701 ggcgggagtg ccgtccgccc gccacgagct ggtcgccgtc ttcggcgtgc tcgaccggcc
     2761 gggtctcgtc gcggtcgtcg accccgttgt ggttctggtc gacgagcttt tgctccaggt
     2821 tccgcttctc gctctccagc cgggagacgc ggtcacgctc ggccagtcgc tcctcgcgca
     2881 gtcggcgacg ccgggcgacg ccgcggcgca tgccgccgct gaccatcgcc aggccgatca
     2941 gaacgcccgc cgcggttccc acgccgagca ggaacatctc gaaggacgtc agcgtgaagt
     3001 tccagtcgag cacggagatc ggagtggtcg ccgtcgccgt ggtctcctgg acggagatct
     3061 cgatcaagac cgcacccgcg agcacgatca ggagaaggcc caatagaacc atgtgttctc
     3121 acctcgaagg cagatgtggc gtgacccccc gtctgcccgt aaaacaaccg ttcatgcccg
     3181 ccggggtttt acatgctgtc gtccatgatc cgcgtttgct cgggtatggg cgttttatga
     3241 gtgagctgca gcaggttgaa gaggagatcg cccgcatccg cgccgaggcc cgttccctgc
     3301 gggagcagat cggtgaccgg gcgggtgaag gtccggccga ctcggccgaa ctgtcctccc
     3361 tcatcgccgg cgccgaccag ctcgacaccc tcgcggagga gctggaaggt cggcgcgaga
     3421 ccctgaagaa ccagggctga caatcttcgg cgccggtcgg gtccggcgcg acccttccgg
     3481 cgccgaagcc ccgaaccttc ctgccacgaa acctgccgac cctgcgcgcg cgtgcccacc
     3541 tgggctgatc cccgcatgga acctcctcgg cggaagacgg cgctgagccg tacctgagag
     3601 aacagaaagc gctctcgcgc caggatcgtc ctgccgattc tggacttttg tcaagactag
     3661 gattaacttc cgggaaatcc ggtgacaatc gagaaagcgc tctatgtgat tcaggcgatc
     3721 cttgaagcac gtctgtgagc tgctgaaaca cgagaaaaca ccagggaacg ttccctggag
     3781 gtcacgacga tcgttatctc gcagcccatt gacaaccccc tgggctccgc tcgaccctca
     3841 ctccagggaa cgttctcttc atgatcaaaa ataggaaggt tccatcggca tgtctcaccc
     3901 ccctcgccgc cgtgccgcgc ggctgctggt gcccctgatc gccgcttccc tcctggccgc
     3961 ctgtggtggt ggggagaaca cgccggctcc cggcgcgacc ggctccgccc ccgctcccgc
     4021 cgccgccgaa ccggtcaagc tgacggtcgc cctcttcagc gacttccact acgggccgct
     4081 gtacgaggag ttcaagaaga cccacccgaa cgtcgagatc accgagcgcc gggcgcagtt
     4141 caacgaccac cacaacaacc tggtcaccca ggtcgccacc ggcgcgggcg ccgccgacat
     4201 cgtcgccgtc gagggcggct tcatcgccac cttccgcgag gtcgccgaca agttccacaa
     4261 cctcaacgac ttcggcctcc agtcgcgcca ggccgagtac ctcgactgga agtggcagtt
     4321 aggcctgtcg aaggacggtt cccagctcat cggcctcggc accgacgtcg gcggcctggc
     4381 catgtgctac cggcccgacc tgttcaaggc ggccggcctg cccagcaacc gcgacgaggt
     4441 cggcgccctg tggccgacct gggagcagta cgtcgagacc ggcaagaagt tcgtcgccgc
     4501 gggcggcaag gccgccttca ccgacggccc cggtgagcac ttccgcgcca tggtcgagca
     4561 ggcccccgtc ggcttctacg acaccagcga caaggtcgtg gtcggctcca accccgacgt
     4621 gcgcaaggcc tgggacgtct cggtctccat gatccagaac aagctgtccg gcaagctcgt
     4681 cgcgttcacc cccgagtgga cgaccggcat cgccaagggc accttcgcca cgatggtctg
     4741 ccccgcatgg aagaccggcg tgatcaagga ccagaagccc ggcgagggca cctgggacat
     4801 cgcggccgtg cccggcggcg gcggcaacca gggcggcacc cacctgctcg cccccaagca
     4861 gggcaagcac cccaaggagg ccgccgagct gatcaacttc ctgaccagca aggagagcca
     4921 gctcaccctc tggaaggacg cctcggccct gccgtcgctg cccggcctgt acaccgaccc
     4981 ggccgtcgcc gacttcgtga acccctactt cggcgacgcc cccatcggca agatcttcac
     5041 cgacgccgcc aaggcgctga agccgcagta caccggcccg aagtcgggtg acgtgaacgt
     5101 cgccatgggc aacggcctcg gccgcatcga gctccagggc caggaccccg aagagtcctg
     5161 gaagcaggcc gtttcggact ccgaaaagat caagtagccg tacgccgcgg ggtggccgga
     5221 ccggccaccc cgccttccct cgaaaggagc gccatggcca cgcgtgcccc ggaacgcgca
     5281 gcgccgccac ggcgaccggg aggcaagcgc cggctgaatg cccgccactg gcggcacgcg
     5341 gtcgacgtca aggcctcgcc gtacgcgtac gtcgcgccgt tcttcctgct cttctgcgcc
     5401 ttcgggttgt tccccatcgg ctacacgctc tgggtgagcc tgcacgagtg gacgctgctg
     5461 aaggacgagc acaccttcgt cggcctggag aacttcaggg tcctgctgac cgactcctac
     5521 ttctggaacg ccacgtacaa cacgttgtcc atcggtgttc tgtcgatggt gccgcagttg
     5581 ctgctggccc tgtggctcgc ccacctgctc aaccggccgc tgcgggcgca gaacttcttc
     5641 cggatcacgc tgctgctgcc caacgtcacc agcgtggtgg cggtcgtggt gatcttctcg
     5701 cagatcttcg gccgtgactt cggcctgatc aactgggtca tcacgagctt cggcttcgag
     5761 ggcgtcgcct ggcgcgacgg caccctgagc tcccacctgg ccatctcgac gatgatcatg
     5821 tggcggtgga cgggctacaa cgcgctcatc ctgctggcgg cgatgcaggc cgtaccgaga
     5881 gagctgtacg aggccgccac catcgacggc gcgtcgagtt ccacccagct ccgcaagatc
     5941 accgtcccga tgatccgccc cacgatcgcc ttcgtggtga tcacctcgac catcgggtcg
     6001 atgcagatct tcgccgagcc gctgctgttc ggcgcctaca ccctcaccgg tggccaggac
     6061 cggcagtacc agacgctttc gctgttcttc tacgagaact acatgcgcct cgacttcggc
     6121 ttctcgtcgg ccatctcctg gatgatcttc atcttcatcc tgatcatcgc cggtatcaac
     6181 ttcctgctca cgaaccggat gaagggaagc gtccgatgaa cggccgtcgg gtcggcaacc
     6241 ggctgaccta cctcacgctc accgcggtcg ccttcttctt cacgatcccg ctgtactact
     6301 cgatcgtggt ggcctcccgc gacaacgcct cgctcgcctc ggtcccgccg ccgctgttcc
     6361 cgggcggaaa cttcttcgag aacgtctccc gggtcttcga caccgtgccg ttcggcctgg
     6421 cgatgctcaa ctcggtcttc gtggccggcc tgatctcgat ctcggtcatg ttcttctcga
     6481 ccctggccgg gttcgccttc gccaagctgc cgttccgcgg ccgcaacatc ctgctgctga
     6541 tgaccgtcgg cacgatgatg gtcccgaccc tggccggcat catcccgctc tacatcctca
     6601 tggtgaaact ggagtgggtc ggttctctgt acgccgtcat cgtgcccgcg ctggtcaacg
     6661 cgttcggcgt gttcttcatg acgcagtatc tgtcccgggc gctgcccacc gaactccttg
     6721 aggccggccg cgtcgacggc tgcacgacct ggggcctggt gtggcacgtc gtcttcccgg
     6781 cggcccggcc ggcggcggcc gtcctcggca tgctgacctt catgacggcc tggaacgact
     6841 acctgtggcc gctcatggtg ctcaccccgg agaacccgac ggtccaggtg gcgctgtcga
     6901 ccctggccgc cggttacgtc aacgactacg tgatgggcct cgcggggacc gccctcggca
     6961 cactgccgct ggtcatcgtg ttcgcctttc tcggcaagca catcatcgga ggaatcatgc
     7021 agggggcggt caagggatga cgccggacat cgagtttccc gaggggttca tctggggtgc
     7081 cgcgacggcg tcgtaccagg tggagggggc cgctcgggaa gacgggcgcg gcgtgtccat
     7141 ctgggacacc ttcgcgcgca cccccggcaa ggtcgccgac ggccacaccg gagacgtggc
     7201 ctgcgaccac taccaccgct atccggacga cgtgcgcctc atggccgacc tgggcctgtc
     7261 ggtctaccgg ttctccaccg cctggccccg ggtcgtcccc gacggctccg gcccggcgaa
     7321 cccgcgcggc ctcgacttct acgaccgcct ggtcgactcg ctgctggacg cgggcatcac
     7381 gccgtacgtc actctctacc actgggacct cccgcagaac ctggaggacc ggggcggctg
     7441 gacctcgcgc gacaccgcgt actacttcgc cgactacgcg gccgccgttc acgcccggct
     7501 ctccgaccgg gtctcgaact ggaccaccct gaacgagccc tgggtctgcg ccttcctcgg
     7561 ctacggcagc ggtgtgcacg cccccggcgt gaccgacgcc gcctcggcct tcaaggcggc
     7621 ccaccaccag ctgctcggcc acggcctggc cgcccagaac ctcaccggca ccctgaccct
     7681 gacgctgaac atggcgcccg tggtcacccc ggcgcagatc gtggacgtcg cccacgtgct
     7741 caccgacgac gacgccgagg cgatcaggcg ggtcgacgcc ctgctgaacc ggcagttcct
     7801 cgacccggcg ctgaagggga cctacccggc cgaggtcctg gacatcgcgg ccgagcacgg
     7861 cggcctcgac cacatccgcg acggcgacct ggagatcatc cggcagccga tcgacctgct
     7921 cgggatcaac tattacaacc cgtgcgtgat ccaggccgcc gcgggcgcgg tggccccccc
     7981 ggcctggccg ggaaccgacg gcatcgagtt cgtcaccatc gagggcccgc agaccgcgat
     8041 gggctggccc gtcatcccgt cgggcctgtc ccgcctgctg gtgcggttgt cgcacgacta
     8101 tccggacgtc ggcctgatca tcaccgagaa cggcgccgcc ttccacgaca aggtcgtcgg
     8161 cgaccgggtg cccgactccg accgggtcgc ctacctggac ggacacctcc gcgcctgcca
     8221 ccaggccatc gcggagggcg ccgacctccg gggctacctg gtgtggtccc ttttcgacaa
     8281 tttcgagtgg gcggaggggt atcaccagcg gttcggtatc gttcggatcg attacgccac
     8341 acagcgccgc ctgcccaagg acagcgccct gtggtatcgc gacgtcatcc agcggaacgg
     8401 catcgagtga aacgtccaac cttggaggcg gtcgccgccc gcgccggcgt gtccaagtcg
     8461 accgtctcaa gggtggtcaa cggcgacacg accgtgacgc cgaacttccg cgaactggtg
     8521 ctgcgggcgg tgaacgaact cgggtacgtc cccaattcgg tcgcccgcag cctggtcacc
     8581 cagcggacca actcgatcgc cctgatcgtg tccgaccccc cagccgggct gttctcggac
     8641 gacccgatgt tctcgacggt ggtgcgatcc gcgtcgcggg ctcttgaggc ggcgtccaag
     8701 caggtcgtcc tgatgctggc ggggtcggac gagagccggg tgcgcgttca ggagtacatc
     8761 gccgccggtc acgtggacgg cgtgatgctc gtgtccttct acggggccga tccgctgccc
     8821 gcggcgctga tgcggatggg cctgccgatg gcgtccttcg gcaagcccgt ctctgcgccg
     8881 tccgtcccct atgtcgacaa cgacaacctg gggggagcgc gacaggcggt cgagcacctg
     8941 ctgtcccggg ggcgacggcg gatcgcgacc atctcggggc cgctggacat gatcgcgtcc
     9001 caggatcgtc tgacggggta tcgggagacg ctgcgggaca ccggccgacg gtcgatcatc
     9061 gcggtcggcg acttcacgag ggtgtccggg gaccaggcga tgtgccagct cctggaggac
     9121 gatccggggc tggacgcggt cttcgcggcc aacgatttaa tggccatagg ggcacttcac
     9181 gcgcttcggc gagccgggag acgggtgccg gaggacgtgt ccgtggtcgg gttcgacgac
     9241 atagaggccg ctctctacac cgacccgcca ttgaccacgg tacgcagccc gatggccgac
     9301 caggccttgg cggtggtcag cctgctgctg gggctgttcg aggacggcga catcgatccg
     9361 gtgatactgc cgacggaact gatggtccgc gaatcgggct gaacgatgta gctcgtcggt
     9421 tcagcggcgc agggcccact ccaccgccgg gcagcggttc atgatcacgt cgagtccggc
     9481 ggccagggcc ctgtcgcccg ccgcctcgtc gtacacgtcc aggggtagcc ataccgcgcc
     9541 cgctcccacc ttgacggctt cgtcgatcac gtcgccggcg aagactgtgc ggcggtagat
     9601 cgccaccacg tcgatgggca ccgggacgtc ggcgagggtg cggtaggtcg tctcgcccag
     9661 gacggggcgg ccgtccgggt gtacgggaat gatgcgtttg ccccggtttt tcatgagttt
     9721 ggcctggttg tagacggtcc tgcctggatc gccggacagg ccgacgaagg cccatgtcgt
     9781 cgtgtcgttc agcaggcgtc ggatggccgt caggtcggcg aaacgatctc ccatgtcttg
     9841 gtgcaacaac ctggtcgccg ggtctcttcc ggcacaggtc agggccgttt tcatgacggc
     9901 acccatgaca tttgcccaca gaggattggt tgaacttgta actagaagct cctggggtta
     9961 tccggaattc ttcctgttag cagaaagcag ggagatggca gtgaatgacc agtatgagct
    10021 ttattgcctc gcggaccggc ttttttatga cgcccccgac cggcgcggaa ccgatattcc
    10081 ggatttcgcg gtggccgggc gtgacgttcc gcgtggctgg tcccaccagc cgtccgacac
    10141 ctggttccac tatgccccga ccggccatga tgttccgccg cagggctgga agatccatgt
    10201 gtcggccggg ctggccgatg cggcgcgggt gctggaaatc gtctgggatt attgcgtcga
    10261 acgtgatatc cccttcaaat tcctgcgcag ccggtctgtt gtcacgatgc tcaactcaaa
    10321 aggggcttcg cggggttcga gcggcaaact ggtcaccatc taccctcggc aagattgtct
    10381 tgagcttacg ctcaaggagc tcgacgggct gctgacgggg gtgcgggggc cgtacatcct
    10441 gagtgatctc cgttacggcg acgggcccct tttcgtgcgc tacggcggat tcgtggcccg
    10501 gcgctgtgcc gcccccaacg gggagctcgt gccggcgatg gagaacgacc ggggcgagct
    10561 ggtgcccgac gtgcggggag cctcgttcac gacccccgaa tgggtgactc tgcccgactt
    10621 cctcagagcc catctggagg ccaggaacgc ggtcacgacc ggcgagctgc cctattcggt
    10681 cgactcggtc atgcacttct ccaacggggg cggggtctat ctcgccaccg accggcggac
    10741 cgacgagcgg gtcgtgctca aggaggcccg gccgatggcg gggctcgacg cggccgagcg
    10801 tgacgcggtg gcgcggctgc agcatgagcg tgacgtgctg cgacggctcg acgggctcga
    10861 ctgcgcgccc ggttatcgcg actacttcgt gctcggtgac caccacttcc tggtgatgga
    10921 gttcgtcgac gcgacgccgc ttcagcgcac gctggtccgc acgtttccgc tgtccaaggc
    10981 cgacgcgacg gccgagtcga tcgccgaata caccgtctgg gcgctcgaca cgctgcccaa
    11041 ggtgcgggcc gccgtcgagg cgctgcacga gcggggggtc gtcttctgcg accttcatcc
    11101 gaacaacatc ctgatcacgc ccgacgggcg gctcgtcctc atcgacttcg aggtcgcgac
    11161 gttcatcgaa gaccgcggcc ggtcggtgct ggcccatccg gccttccagg cgccggccga
    11221 ccggcggggc gccgacgtcg acctctacgc cctggcgtgt ctcacgctgg gcctgttcgc
    11281 gccgcagctc acgatcaccg tgccgctggc gcgggccaag gcgacacagc tcgggcacat
    11341 gatcgtcgac accttcccgg tgccgccgga gctgatcaag cgcgccgtcc acacgatcac
    11401 cgggcccatc gggggcgggc ccacggcgag tgtgaccagc ggcgatccga tggcggcgat
    11461 ggcgcggggg atcctcgcca gcgccacgcc ccggcgctcc gaccggctct ttcccggtga
    11521 cgtcgcccag ttccatcccg gcggcgggat caacctggcc cacggcgcgg cgggggtcct
    11581 gctcgccctc gacgcggcgg gagccggccg gttccccgac tacgaggagt ggctcctccg
    11641 ccgaacccag gacagccgaa cccaggacct ccaggcccag gaccgccaga acctggagtg
    11701 tccgcctggc ttctacgacg ggctccacgg cgtcgcctat gtgctcgatc ggttcggcca
    11761 tgtcgaccag gcgctcgatc tcgtcgatcg ggccatgtcg gggccctggc gggagctcga
    11821 tctcagcctc tactcggggc tggccggcat cgggctcaac ctgctccacc tggggctcga
    11881 cgcccgcccg ctggtcgagc tctgcgccga gaggcttcct gacgacgtac cggagatatc
    11941 tggcggttcg caccccaggg caggtctcct gtacggcctg agcggccccg cgctcctctt
    12001 cctgcgcgcc tacgaccaca ccagagaccc ggcactgctc gatctggccg aacgggcgct
    12061 gcgcctcgac ctgaagcggt gcgtcgtcac cgccgacggg tcgttgcagg tcgaccaggg
    12121 gtggcggacg ctgccctacc tcgacgaggg ctcggccggc atcgcgatcg tgctgggcga
    12181 cctgctccga cggcggcccg gctcctcgct ggccgccgcg ctgcccgacc tgctgaaagt
    12241 gggccgctgc cggttcttcg tgcagccggg cctgttcgcc gggcgggccg gcatgatcct
    12301 ggccgaccgg acgctcgtcc ccggcctcga ctggcacgtt cttccctacc gtgacgggat
    12361 cgccttcccc ggcgaccagt tgctccggct gtcgatggac ttcgccaccg gcaccgccgg
    12421 ggtcctgttc gccctcagcg gcaccccgtt gcccttcatg catccactcg gcgcggagcc
    12481 ctacgccatg ccgggtggcg ccccccttca gctgtcgacc aaggaggtga tcggggcccg
    12541 gaacagctag ctccaccttt ttaaaagatc tcgaagtcct cccgatagag aaatttcaca
    12601 aaggagtatc accatggttc ttctcgacct tcaggcgatg gagcttcccg gcggcggcgg
    12661 cggtcacggc ggcggcggtg gcggcggtgg cggcagcacg ctgacgctgc tcggctgcgc
    12721 gtcccagacg cccagcaacc tgagcctgct gctctgccac taggcacccg atcggggccc
    12781 tgggctcgcg ggagcccggg gccctccctt cgcagaacac actccaccca cgtgaagaga
    12841 gggactcggc gttgcggacg gccgaccggc tgacaaccga ggcgatcagg cgtagcgggc
    12901 ccgcggcggg cgtgctcgtc gctgtctccc tggtcggcgc cggccttgag ctggcactgc
    12961 cgttcgtgct cggccgcgcc gtcgacacct tctccctgac gtgggtgata tccgccgggg
    13021 ccgtcgtggt gctcctcgtc gtctgcgacg gtctcggcgt ctacgcgagc ggaaccggtg
    13081 gcgcgcgggc ggcggcctgg ctgcgccacc gggcgctctc gcatctgctc ggcgtgggtc
    13141 ccggggtgac ccgacgcatt cccgcgggcg atctggtgac ccggctcggc gtcaacgccg
    13201 aggaggcggg gcgggccgga gacgcggtgg tcgcgtcggt ggcgctcgtg gtgccgtcgg
    13261 ccggggcgct ggtgctgctg gtgctgatcg atccgtggct ggccctgacc ctggcgggcg
    13321 ggctggttgt gatcgttttc gtactgacac ggttcttgaa gacgtccacg acgatcgccg
    13381 gtagatacca ggaggcgcag gccgacatcg ccgcgcgcct ggtcgaggcg gtcgcgggcg
    13441 cccgcacgat cgccgccgcc gggaccgccg agcgggagac ccggcgggtg ctgaccgcgc
    13501 ttccggtggt ccggggccat gcgatggcgc tgtggcgggc caacgccgac gcgggggtgc
    13561 gggccgcgat cgtggtgccg ctcctcgagg tgctggtgct ggccgtgggc ggctggcggc
    13621 tgtcggcagg ggagctcacc gtcggcgagc tctacgccgc cgctcgatat gtggtcatcg
    13681 gcgctggtct ggggcccgcg atcgggtcgc tgggccggct ggcccgcgcc cgtgcggccg
    13741 gcgcccggct ggccgagatc ttggacgaat gcccggtggc gcacggggtt cgcgagctgc
    13801 ctcccggccc ggggaccctc acttttcgcg atatctggcc agatgacctg gagatccagg
    13861 gcggcacctc ggtggccgtg gtcggctcgg gggcgtcccg tttcgcccgc ctcgcggccc
    13921 gcctcgacga cccggccgtc ggcgacgtcc tcctcgacgg tgtcccgctg cggtcactca
    13981 cccggcggtc gctcagaagc gccatcgggt acgccgtcgc caagccccac ctcatcggag
    14041 acaccgtcgc cgaggcgacc ggcgactccc gcgaggcggc cgtggccgcc ggggccgacg
    14101 acttcatccg ccggttgccg cacggctacc gcaccccgcc ggccgaggcg cccatgtccg
    14161 gcggcgaacg ccagcgactg ggcctgacca gggctttcgc gaagggaaac cgcctgctgg
    14221 tgctcgacga cgccacctcc agcctcgaca ccatcaccga acgccgggtc ggcaccgcgc
    14281 tggccgccga cacccgcacc caggtcatgg tgacccaccg ggccgccgtc gcggcgcggg
    14341 ccgaccgggt gatctggctc gatcagggtc gggtacgagg cttcgaccgg cacctcgcct
    14401 tatggcgcga cccggattac cgagccgttt tccagggcgg ggaggcgcag tgaactcccg
    14461 tgggtcaggc gtggccggtc ggaacgaggt ggccgcgtga tctcattcgg tcatcggacc
    14521 cgggtcggct cgtttctctg gcgatcgttc aacgctcagc cggggcaggc gtggcggttc
    14581 gtgctgtggt cgctggtcga ggccgcgccc gcgttcgtca tcgggctggc catcgcccgg
    14641 gcggtcgacg cgttcaccgc gcatcaggcc gtcgccgggc tctcctggac gttcctgctc
    14701 ggcatctcct ggatcttcgc cgccgtcggg gcgcggcagg tggtcgtcac tttggccggc
    14761 atcgtggagc ccgtgcggga ggagttgctg accgcgaccg ttcgcggggc actggaggcc
    14821 gggagaaacg acgccgccgc cgtcaccagg gccaatctcc aggtcgaggt ggcgcgtgac
    14881 gccttcaccg gggtcatcgg gtcggtgaag gcgttcgtgt tcgcctttct cggggtcgtc
    14941 gccggggtca tggcgctgat gccggaactg ctcctgctgg tgctgcctcc gttgctgctc
    15001 gcgctggggg cgttcctctt ctcgctgccg gaactggcga agcggcagca cgcctatctg
    15061 ctcgccgacg aggccacggc cgagagcctg gtcagggtca ccgccgcgct cggcgacgtc
    15121 gccgcgtccg gcgacgagga gcacgccgcc cgatacgccg gttcgcgttt cgacgatcag
    15181 cggcgggcgg ccgggaagct ggcgggggtc acgacgctcc gtaccgtcgt gctgggaacg
    15241 ggggcctggg cgccgatcct gctcgtgctc gtctacgcgc cccggctggg cgcgagcccg
    15301 ggggtcgtgc tcgggacgct cgcctatgtg atgcagtcgc tcacgcccgc gctgttcaac
    15361 ctggcgagcg ggctggggga gagcggggtg cggctctggg tcacgctgac ccggctgcgg
    15421 gccgcgcttc cgccgccacc gcaggagacc caccggtccg agggggtgca caccgagctg
    15481 aagggggtca cgttcgccta tgggccgcag gccctgccgg tcgtcgaccg cctcgatctg
    15541 gtcgtccccg aaggggagca cctggccgtc gtcgggccga gcgggatcgg gaaatcgacc
    15601 ctcgccgccc tcatcgccgg actcgtcgtc cccggtcagg ggcgggtgac cgtcggcgga
    15661 gtgccggccg tccggctcca caaggggcag cgggtgctga tcccgcagga ggcgtacatc
    15721 ttccggggga ccgtcgcgga gaacctgggc gatcaccaac cggcgaggat gcggcaggcc
    15781 ctcgacgcca tcggcgccgg gcacatcagg ctccaggtca ccgagctcgg gccggccgac
    15841 cggcagctcg tcgccctggc cagggcattt ctcgccgacg cgccgctggt catcctcgac
    15901 gaggccacct cctgcctcga tccggcggcc gaggcccagg tcgagcgggc cttcgcggag
    15961 acggggtgca ctctgatcgt catcgcgcac cggatcagct cggccctgcg ggcccggcgg
    16021 gtgctggtca tggacggcac ccggatcgtc accggcaccc atcaggaact tctggccgcc
    16081 tcgcccctgt acgcggatct ggccgggcat tgggaccccc gactcaggca ggtgtcatga
    16141 tcgagatcat tcacgggcac gtcgtctccg acccgtaccg ctggctggaa gatcccgcgt
    16201 ccgacgagac gcgagcctgg caggcccagc aggaggtcgt ctggcagagc cagctcctcc
    16261 ccggccggga cgggttcctg gccaggatcg aggagctgag cgacaccggc gtcgtgggcg
    16321 cccccgtctg gcgggcgggc accgccttcc gcgtccgccg cgacccgggc cgccgcctgc
    16381 cggtcctcta cgccgacgac cggccgatcc tcgaccccga ggcgatcgac cccggcgcga
    16441 ccaccctgct cgacgcctgg cacccctcgc ccgacggcga actcgtcgcc tgccagctct
    16501 cccggggcgg cgacgaacgt tccgagctgt acgtcatcag cgcccgcacc ggcgcactcg
    16561 tcgacggccc ggtgggcggg ctccgctact ctccggtggc ctggctaccg gacagcgacg
    16621 gtttctacta cgtccgcgac cgccgggccc gcgtccacca tctcggcggc gacgacctcg
    16681 acgtggccga cgccgacggc atcgccctca gcgccgacgg ccgctggctc accctctcgg
    16741 tcaaccgggg gccgggcaac gatgtatggc tctgtgacct ggtcagcccg gcccggtgga
    16801 ccgtccagca ggacgtggcg gccaggtcgg cggtggcggt ggggcgtgac gggcgggcgt
    16861 acatggtgac gaccctcgac gccccccgtg gacgcctccg cgtggccgat ccggcggtgc
    16921 cgcatgagtt ccgtgacctg gtcccggaag acgccgaggc cgtgatcgcc gatttcgttc
    16981 tgctcgacgg ggttctcctg gtggcgtggg tgcgccacgc catcggggag atctccgtcc
    17041 atgatcccga gaccggggag cgtcaaggag cggtcccgct ccccggtctc ggctccatcg
    17101 ggcggatgtc cgcccggggg cacgaggtgt ggttcaccta ctccgactac gtcacccccg
    17161 agagcgtcta ccgctatgac gcccgcaccg gcgagaccac cctgtgggag gcggccccgg
    17221 gccgggccga gctgcccgag atcgagtcgc accaggtcgt ctaccagtcg gccgacggca
    17281 cgccggtccg gatggtcgtg ctcggccggg ggctgccggg gccgagcccg tgcatcctct
    17341 acggctacgg cgggttcggg gtgccgctca cgccctccta ctcgtcctat gtgttgccgt
    17401 ggctggaggc tggtggcgtt ttcgcgttcg cccaggtcag gggtggtggc gaagaagggg
    17461 aggggtggca tcgggccggg atgcgggggc ggaagcagaa ctcgttcgac gatttcgccg
    17521 ccgccgcgga gaccctgatc gcctcgggct ggaccaggcc cgacctgctg ggggtcaccg
    17581 gtgagtccgg gggtgggctg ctcgtcgggg cgctggtcac ccagcgtccg gaactggtcg
    17641 ccgccgccgt gtgctcggcg ccggtcctcg acatgatcag gttcgagaag tcggggctcg
    17701 ggagttcctg ggtgccggaa tacggctccg ccgacgaccc cgagcagttc tcctggctgc
    17761 tggcctactc gccctaccac caggtcaaag agggggtcga ctatccggcg accctgttca
    17821 ccgtcttcga cggcgacagc cgggtcgacc cgctccacgc ccgcaagatg tgcgccgccc
    17881 tgcagggggc gacgtcgggc gtccggccga tcctgttccg ccacgaagcc ggcgtcggcc
    17941 acgcgggccg atcagccgac cgggcggccg ggctggccgc cgacatgctg gcgttcctgg
    18001 cccgggagct gggcggtctt taggccgagc ggggcaggaa gagggccagg gccgatgggg
    18061 gcgcggtggt gagggacatc tcgaaccaga ccttgttgcg gccgccctcg cggacgatgc
    18121 cccatcggtc ggctaaggcg tcgagcaagg gcaggccgcg gccgttggtg gcggtcgccg
    18181 tcgagtggcc ggcacagggg ggttcggtgg agccgtcgtc ctggacgcag acgcggacct
    18241 cctccgagga gaaccagacc gtcacggtga acacgccgcc gtcgcccgat ctggagtgga
    18301 tgaccgcgtt cgtggcgatc tcgctcgtca gcagaacgca gtcgtcgtgc agcgggtggt
    18361 ctctgccgat cgtcgccgag accatgcggc gggccagaac tatttggtcg cggcccccgg
    18421 cgagtctggc gacccgggca gctctgaggt cagtggtgat agtcgtgtcg atggagtcga
    18481 gtgtggtgac gttccccgaa ccgttcatgc gtcctcctcg atgactgcgt gaagaagacg
    18541 cgccaatacc cggtctgaga tgtcacggga aggtgcgact gtgcttccct gagggaaccg
    18601 gccctgccat agggtcgagg aatgctgacg ctgatggcgg tgcacgccca ccctgacgac
    18661 gaggtcatgg gaacgggggg cgtcttcgcg aaatacgccg ccgaaggggt gcgtacggtc
    18721 ctggtgacct gcaccaacgg ggagcagggc gacggggccg gcggagtgaa gccgggggat
    18781 cctgggcact ccgaggccga cgtggccaac cagcggctcg ccgagctggc cgagtcggtg
    18841 gggcacctga agatcgggca cctcgagctg ctcggatacc acgattcggg gatggtcggc
    18901 tgggccggga acgccagccc tgacgcgttc accaacgccg acttcgacaa ggccgtggcg
    18961 aaggtggcgg cgttgatgga ggaataccgg ccgcaggtcg tcgtgaccta cgacgagaac
    19021 ggcaactacg gtcatcccga ccacatccag gcccaccggg tcgcggtggc ggcggccgag
    19081 gcgaccggga tcccggtgaa gttctactac acggcgatcc cccggcggat catccaggcg
    19141 tcgtacgcgg cgatgaagga acagggcaag gacccgggct gggagctgcc ggaggacttc
    19201 ggcacccccg acgagctgat caccagcgtg gtcgacaccc acgagcaggc cgacgcgaag
    19261 atcgcggcgc tgcgggcgca cgccagccag ggcgacagca tcgccctgtt gtcgatgccg
    19321 cccgagatgc agcgcatggc catgtcgacc gaacacttca tccgggtgtc caccaaggtc
    19381 acggcgcccg accacgaaga cgacctgttc gccgggctgc gctgatcagg cgcgggcccg
    19441 ctgctcataa agggcctttt cctggacgtt cctggtgagt tcggccgcct tcagaaaggc
    19501 cgctctggct tcctcgactc gtccactgcg ttcgaggaga tcgcctctca ccgcggacag
    19561 gtgggggttg ccttcgagcg gcagtccgtc gacgatcttc agcccggcct ccggcccttc
    19621 ggccatgccg accgccacgg cgcggttgag ttcgacgatc ggcgacgggg ccacgtgggc
    19681 taacagttgg tagagggcgg ccatccgggc ccagtcggtg tcggcgaaaa ccccggccct
    19741 ggcgtggacg gccgcgatgg cggcctggag gccgtacggg cccaggaccc ccgtcgactc
    19801 ggcgcgggtc agcgcttcca gacctcgccg gatgaggagg cggtcccatc gtgtccggtc
    19861 ctggtcggcg agcaggaccg gctccccgcc ggggccgatg cgggcgttca ggcgggacga
    19921 ctggatctcc agcagcgcct gcaggcccga cgcctcggat gacgtcggca tcagcgcggc
    19981 cagcacgcgg gacaggcgca gcgcctcgaa gcacaggtcg ttacgggtcc aggagtcgcc
    20041 cgacgtcgcc gagtagccct cgttgaagat cagatagatg acctcaagga ccgaggccag
    20101 ccgcgcgggc agctcctccg cgggcggcag ctcgatcggg accttccgca gggcggcctt
    20161 ggcccggtag atccgctggc cgaccgtcgg ttccgggacc aggaacgccc gcgcgatctc
    20221 cgccgtcgtc agcccgccca gcagccgcag cgtcagcgcc agccgcccct cgacggccac
    20281 gtcagggtgg caggccgtga agatcagggt gagcagctcg ggttccggcc gggccggggg
    20341 ctgctgggcg agttcgcgga gtttctcctc gtagacgccc tgccgccgca gttggtcgat
    20401 cgccttgcgc ttggcggtcg tggtcagcca gccgcccggg ttctccggca caccctcatg
    20461 tggccaggtc tccacggcga gcaggaacgc gtcttgggcc gactcctcgg ccaggccgat
    20521 gtcgccggtc atcctggcca cggtcgcgat gaccttggcc gactcgatgc gccagacggc
    20581 ctcgatggtg cggatcggat cgggaagccc catgcctccc gatccaatca gaggtcagaa
    20641 ggtcatcagg gggtgcacct gggagacccc ctcccagccg ggccacatgt cgcggtgcag
    20701 tctcatgaag cggttggccc actcgatcgc ctcggcctcg tcgcggacct cgtagatcgc
    20761 gtagctgatc agttccttgg cctcggcgaa cgggccgtcg gtcaccgtca gtttgccgcc
    20821 gacgacctcg acctcggcgg tcttggccag caggccgctc tggtcgacga gggcgcccga
    20881 ctcggtggcc tcccggccga gctgcatgat cgccgacatg agttcggcgg gcggcggggt
    20941 ctcgggctgg gcggtgcggg tcagcgtgat caggtagcgc atgggtgttc tccattcgtt
    21001 ctcgtgtgaa cctacgaccc ctctacgaac ggccggacgg agtttcgaca gccaccggtt
    21061 acttttttct gatttccggc catgctggtc aggtgagcag caggcctccc tatccggggt
    21121 tggcggcgtt cggggcactg gacgccgccg tgttcttcgg ccgtgacgat ctcctttccg
    21181 acctgcgacg gcgtaccggg agcgagaagc tggtcgtcgt cacgggcgcg tccggggcgg
    21241 ggaagacctc gctcgtcgac gtcggcctcg cgggcgggct gcggttacgg cccggagacg
    21301 atccggtcgg cgcgttgctg gccgcgttcg gggccacgat ggaccacgac cggctggccg
    21361 ccgcgccgca tcacctcgac gagctgggcg atcctgggct gatcgtggtc gaccggttcg
    21421 aggaggtctt cgcggcctgc cgcgatctca ccgcccggca gaccttcatc ggcgctctgg
    21481 ccgccacgcg ggcccatgtc gtgctggtgc tgcgggccga tttcaccggt gacgcggccg
    21541 cgttccccga gctggtcgcg gccctttccc ggccgctgat cgtctcgccc ctgtctctgg
    21601 acgaccttcg caccgccatc gagcagcccg ccctcgctct cggggtgacc ttcgaagacg
    21661 gcctggtcga ggagatcctc gccgaccaga acggtgacct gcccctgctg gcccacacgc
    21721 tgcgggtgat gtgggatcgg ggggcgggcg acgtactgac attcgaggct tatcgggcca
    21781 ccggccgggt gaccggggcg atcccccgca gcgccgagcg cgccctggtc cgcaacgacg
    21841 ccagggcggc gctgtcggcg ctgaccgggc cgctcggcac gctgcgaacg ggcccgatgt
    21901 cgccggagct ggccccgttc gtggcggccg gactcgtgcg gtcggacggg gagacggccg
    21961 agctggcgca cgaggcggtg gtccgggcct ggccccggtt caccgcgtgg acggaggccg
    22021 atcgggcggc cggtcaggtg cggcgggagt tcgccgtcga cgccaaccgg tgggtgctga
    22081 gcgggttcga cgcggcccac ctctaccagg acgcccggct ggcggcggcc cgcgcggcgg
    22141 tgaagcgggc ccggcacgat ctgtccccgg ccgaggtggc gttcctcgac gcgagcgcgg
    22201 cccaggcgat ggcggggcgg cgggccgcgg agaaacgtac attcctgcgg ggtctgctct
    22261 ccatcgcggt ggtcgcgctg ctcgtcgtga gtttcgggac gaccggcgcg ctggcgctgc
    22321 tgttcgacgg ggccacccgc gaccgggacg cggcggtcga ccggagcacc acggcggtgg
    22381 cccgccatct gctcgcccag ggcgacgcgc tcgccgccga ccagccggtt ctcgcccggc
    22441 tgctccggct ggcgggggcc gtgatcgcgc ccgcgctgcc cgaggcggcg gccgggctgc
    22501 gcgcctcggc ggtgcatccc gcgctcgacg tgctgcaccc gccgggcgtc
//
