LOCUS       NZ_BBXD01000008        20933 bp    DNA     linear   CON 08-AUG-2024
DEFINITION  Herbidospora mongoliensis strain NBRC 105882, whole genome shotgun
            sequence.
ACCESSION   NZ_BBXD01000008
VERSION     NZ_BBXD01000008.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Herbidospora mongoliensis
  ORGANISM  Herbidospora mongoliensis
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Herbidospora.
REFERENCE   1
  AUTHORS   Komaki,H., Ichikawa,N., Oguchi,A., Hamada,M., Tamura,T. and
            Fujita,N.
  TITLE     Genome-based analysis of non-ribosomal peptide synthetase and type-I
            polyketide synthase gene clusters in all type strains of the genus
            Herbidospora
  JOURNAL   BMC Res Notes 8, 548 (2015)
   PUBMED   26452464
  REMARK    DOI:10.1186/s13104-015-1526-9 Publication Status: Online-Only
REFERENCE   2  (bases 1 to 910721)
  AUTHORS   Hosoyama,A., Oguchi,A., Ichikawa,N., Kimura,A., Ohshita,R. and
            Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-MAY-2015) Contact:Director-General Department Of
            Biotechnology National Institute of Technology and Evaluation,
            Biological Resource Center (NBRC); 2-49-10 Nishihara, Shibuya-ku,
            Tokyo 151-0066, Japan URL :http://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Noncontiguous Finished
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: newbler v. 2.6
            Genome Coverage                   :: 62x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001570545.1-RS_2024_08_08
            Annotation Date                   :: 08/08/2024 02:40:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,280
            CDSs (total)                      :: 8,202
            Genes (coding)                    :: 8,113
            CDSs (with protein)               :: 8,113
            Genes (RNA)                       :: 78
            rRNAs                             :: 4, 6, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 4, 5 (5S, 16S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 21 of 89
            Pseudo Genes (incomplete)         :: 71 of 89
            Pseudo Genes (internal stop)      :: 4 of 89
            Pseudo Genes (multiple problems)  :: 7 of 89
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:23:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 545143
            Orig. end                         :: 566076
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBXD01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20933
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20933
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20933
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10933](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10933
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    452..466
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.93"
                     /tool="antismash"
     gene            2163..2459
                     /locus_tag="AW272_RS02750"
     CDS             2163..2459
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020542548.1"
                     /locus_tag="AW272_RS02750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_061296783.1"
                     /transl_table=11
                     /translation="MWITDWTSRAACRGADPDALFVQGAAQNRAKLICRGCPVRTECLA
                     DALDNRIEFGVWGGMTERERRALLRRRPDVDSWRDLLELAKEEYERTNELIAG"
     gene            complement(2463..3581)
                     /locus_tag="AW272_RS02755"
     CDS             complement(2463..3581)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1157: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019633550.1"
                     /locus_tag="AW272_RS02755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ArsA family ATPase"
                     /protein_id="WP_066360758.1"
                     /transl_table=11
                     /translation="MTTPELDLDGIIDDPGTRIVVCCGSGGVGKTTTAAALGLRAAERG
                     RNVVVLTVDPARRLAQSMGLTSLDNTPRKVAGADGELFAMMLDMKRTFDEIIEAHADPE
                     RARQILTNPFYQSLSSSFSGTQEYMAMEKLGQLRRSGEWDLIIVDTPPSRSALDFLDAP
                     ERLGRFLDGKLIRLLMAPAKAGGRSAFKILNAGFGLVAGVLTKVLGAQVLKDIQTFVSA
                     LDAVFGGFRQRAEQTYQLLQAPGTAFVVVATPERDAMREASYFVERLAEERMPLAGLVV
                     NRVHRSPAPGLSAARSTAAAEDLESRGEHELTAAVLRLHAGRMQLAAREHREQERFASA
                     HPTVPATQVPAMSQDVHDLDGLREIGELLAKR"
     gene            complement(3578..4558)
                     /locus_tag="AW272_RS02760"
     CDS             complement(3578..4558)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019633549.1"
                     /locus_tag="AW272_RS02760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ArsA-related P-loop ATPase"
                     /protein_id="WP_169807477.1"
                     /transl_table=11
                     /translation="MRSRDTDWDGVRLHVVTGKGGTGKTTVAAALALALAAGGRKVLLV
                     EVEGRQGIAQVFDLPPLPYEERRIAVAPGGGDVHALAIDPEEAMLEYLEMFYGLKRMGK
                     ALTKMGVVDFATTIAPGLRDVLVTGKTSEAVRRRDRTGKRVYDTVVMDAPPTGRVSRFL
                     NVTQEVAGLARVGPVRAHADMVRGVMASPETAVHFVTLLEEMPVQETLDGVTELHAAKL
                     PVGGIFVNMVRTVDPVLEGPFDLAELAMGVKAAGLGDDGNAAVIAEALGGEVVEQQRRA
                     ELERTERDALETVGVPRYELPLLADGADLAGLYELAEAIRTQGAA"
     gene            4628..4783
                     /locus_tag="AW272_RS41710"
     CDS             4628..4783
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621623.1"
                     /locus_tag="AW272_RS41710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4177 domain-containing protein"
                     /protein_id="WP_155340753.1"
                     /transl_table=11
                     /translation="MTKWEYVTVPLLTHATKQILDNWGEDGWELVAVIPGPNPEQLVAY
                     MKRAKA"
     gene            4780..5232
                     /locus_tag="AW272_RS02765"
     CDS             4780..5232
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017568440.1"
                     /locus_tag="AW272_RS02765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RidA family protein"
                     /protein_id="WP_066360760.1"
                     /transl_table=11
                     /translation="MSSPEDRLAALGLSLPDVVAPLAAYVPAVRSGAHVYTSGQLPIAA
                     GELLKTGKVGAEVTPEEAYELAKLCALNAIAALRSVVDLDQVVGIVKVVGFVASAPDFT
                     GQPQVVNGASELLGEVFQGAHARSAVGVAVLPRDAPVEVELIAEIR"
     gene            5254..6030
                     /locus_tag="AW272_RS02770"
     CDS             5254..6030
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020542553.1"
                     /locus_tag="AW272_RS02770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_066361199.1"
                     /transl_table=11
                     /translation="MPLPGELGERARDLLAGRLVPVPPRAAATVALLREPPLEVYLLRR
                     AATMAFAAGAYVFPGGSVDPRDAGHDIGWAGPSPAEWAAALNADEDTARGLVCAAVRET
                     FEESGVLLAGDPVDDTTMWEAERLALIGRELSFADFLATNGLVLRSDLLKPWAHWITPE
                     IETRRFDTRFFVAALPSGQRTRDVGGEADTVVWHSPAEALASGYFLMPPTLHTLTMLTA
                     SETIADVFAADPKITTVMPAPVERNGQMVLTTEGQI"
     gene            6030..6812
                     /locus_tag="AW272_RS02775"
     CDS             6030..6812
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013130468.1"
                     /locus_tag="AW272_RS02775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_066360762.1"
                     /transl_table=11
                     /translation="MSGLPLPIDGSGTPTATNVLAPNASPMTLDGTNTWVIGRGESVAV
                     VDPGPDDEAHLSTVVSRLGDRNVEVILLTHGHEDHSGGARRFAELVNSPVRALDRTHVL
                     GEEGLEDGDALTVGGVEIRVIGTPGHSFDSLCFWLPDDSALLTGDTILGRGSTVIAPDG
                     DLADYLRSLDKLRAMAELAEAEALLPGHGPILADPVGKLDEYMTHRRQRLDQIRQAIRD
                     GARDAGEIVEMVYADVPKDLWPAARMSVAAQLNYLKTR"
     gene            6815..7675
                     /locus_tag="AW272_RS02780"
     CDS             6815..7675
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1207: inositol monophosphatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653781.1"
                     /locus_tag="AW272_RS02780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="inositol monophosphatase family protein"
                     /protein_id="WP_245657165.1"
                     /transl_table=11
                     /translation="MRDHLIDVVRTVIGEIRPKLVAAALSGDRSEHRNLRHADNFLSSH
                     DLWLHRRYRELLAERFASFVYASEEGDPEVVGPDPDPDLCVLVDPLDTSELAVRGLNGY
                     TQILVYSRALGRPLAAAVGDLFHHFQVYVAAEGEAHVLTQDGDRHPLRVDGMSVPLRDS
                     LVTNFLMKPADRFGPLARQTRLLAALSEGRGRIGLDFGSIGLCHVAAGFTDAVVEFAKG
                     FAIWDLAPGAYILNCAGGGVYDLTGAPISLDGLLTDIGAAMSTRRKFVATRDETLARDI
                     LRLIG"
     gene            complement(7672..8352)
                     /locus_tag="AW272_RS02785"
     CDS             complement(7672..8352)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017578423.1"
                     /locus_tag="AW272_RS02785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_066360764.1"
                     /transl_table=11
                     /translation="MSTEEVLSRAPLFSALDRESAAALRTSITEVTLTKGQTLFSENET
                     GATLYVVLEGKIKLARTASDGRENLLSVLGPSEMFGELSLFDPRPRTASAIALTDVKLA
                     GLSHDDLRPWLTGRPEVALHLLRALAQRLRRTNDVLADLVFTDVPGRVAKALLDLAERF
                     GQKVEDGIRVHHDLTQEELAQLVGASRETVNKALADFAGRGWLRIEAKAVVIMDMERLY
                     NRSR"
     gene            complement(8394..8984)
                     /locus_tag="AW272_RS02790"
     CDS             complement(8394..8984)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF037675.4"
                     /locus_tag="AW272_RS02790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_066360766.1"
                     /transl_table=11
                     /translation="MPGKADATRQRLLDAALEEFAEYGIAGARVDRVAAVAGTNKAQIY
                     HYFGSKDQLFDAVFNGIVERIVRETPIDAHDLPGYAAALARGYEAHPQVARLATWQRLE
                     RAGDPPVPLAVESMRHKVEVIAKAQAEGILTTEFPPGILMNLVLHLSLVWTAVNPESAA
                     VVETVTPDERAHYVATAVRRLLSGGPGDAEGGA"
     misc_feature    complement(9048..9063)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.61"
                     /tool="antismash"
     misc_feature    complement(9055..9068)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.02"
                     /tool="antismash"
     misc_feature    complement(9057..9073)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.38"
                     /tool="antismash"
     gene            9083..9976
                     /locus_tag="AW272_RS02795"
     CDS             9083..9976
                     /NRPS_PKS="Domain: PKS_KR (3-164). E-value: 8.6e-15. Score:
                     47.0. Matches aSDomain:
                     nrpspksdomains_AW272_RS02795_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF006114.0"
                     /locus_tag="AW272_RS02795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_066360768.1"
                     /sec_met_domain="adh_short (E-value: 1e-31, bitscore:
                     106.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIWFVTGSSRGLGREIVLAALERGDSVAATARTPAQLDDMSQKYG
                     DRILALPLDVTDAEAVEDAVATAVEAFGSIDVVVNNAGWADMSAFEDTPIDNFRAQVET
                     NFFGVVNVTKSVVPVLRRQGHGSLISVSSIGGRLGTPGLAAYQASKWAVNGFTEVIAQE
                     LTPLGIKVTTIEPGGMTTDWGGSSMTIPPISEPYQQSVGAMVRILRQGDHKPLGDPARV
                     AQVIVQIVEMDNPPVRLLLGSDALNGAQYAAHTTAERDATYTELSRSTDRDDATAQERD
                     PLGQAFSTMADGEAAE"
     aSDomain        9092..9574
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AW272_RS02795_PKS_KR.1"
                     /evalue="8.60E-15"
                     /label="AW272_RS02795_PKS_KR.1"
                     /locus_tag="AW272_RS02795"
                     /protein_end="164"
                     /protein_start="3"
                     /score="47.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="FVTGSSRGLGREIVLAALERGDSVAATARTPAQLDDMSQKYGDRI
                     LALPLDVTDAEAVEDAVATAVEAFGSIDVVVNNAGWADMSAFEDTPIDNFRAQVETNFF
                     GVVNVTKSVVPVLRRQGHGSLISVSSIGGRLGTPGLAAYQASKWAVNGFTEVIAQEL"
     CDS_motif       9473..9526
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AW272_RS02795_0001"
                     /evalue="4.90E-04"
                     /label="PKSI-KR_m4"
                     /locus_tag="AW272_RS02795"
                     /protein_end="148"
                     /protein_start="130"
                     /score="12.6"
                     /tool="antismash"
                     /translation="VSSIGGRLGTPGLAAYQA"
     gene            10001..10933
                     /locus_tag="AW272_RS02800"
     CDS             10001..10933
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890380.1"
                     /locus_tag="AW272_RS02800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_245657166.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7.3e-42, bitscore:
                     139.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDSMTVRDVLNATRELIEPAHRAAIDRLSPELRHVAGYHIGWWD
                     EEGRELIGGQGRFVRPALALGCARAAGGHASDAVPMAVATELVNDFSLLHDDVIDGDDI
                     RRERPAAWAVFGLSEALLTGDALLAVAMALVGPAGVRTLADALLDLCHGQASDLAFVDR
                     PEVTLAECMTMAENKTGALLGAACELGALAGGTGDVQRFREFGTRLGLAFRLTDDLRRL
                     VADLACRRKSLPVVAALESRTPAAARLAEALHDQADPEVQAELVEETGAREWALREADR
                     QVELAFAALGQGATPELRLLADLSVGRTR"
     gene            complement(10937..11407)
                     /locus_tag="AW272_RS02805"
     CDS             complement(10937..11407)
                     /GO_function="GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546078.1"
                     /locus_tag="AW272_RS02805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CoA-binding protein"
                     /protein_id="WP_066360772.1"
                     /transl_table=11
                     /translation="MKYQEPQDIQRVLNTAKTVAVVGLSGNELRASNFVGFYLKRHGYR
                     MIPVNPREKEILGETSYPSLSDIPVKIDVVNVFRAPDAVPGIAREAVEIGAGALWLQFG
                     VISEEGARIAEEGGLTVIMDRCMKIEHARYMGRMHWLGFNTGRITSVRTGIH"
     gene            complement(11404..12717)
                     /locus_tag="AW272_RS02810"
     CDS             complement(11404..12717)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (61-231). E-value: 3e-11.
                     Score: 34.9. Matches aSDomain:
                     nrpspksdomains_AW272_RS02810_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168: O-succinylhomoserine sulfhydrylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546079.1"
                     /locus_tag="AW272_RS02810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
                     /protein_id="WP_066360774.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.7e-10, bitscore:
                     34.9, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 3e-14, bitscore:
                     48.8, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 8.3e-09, bitscore:
                     30.6, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDRPFRTEESREFGFETRQLHAGQRPDPNTGARAVPIFQTTSYV
                     FEDPESAAAYFNLQEYGNTYSRIMNPTTAVFEERMANLEGGSGAVAFASGIAAQAAALF
                     TLLEPGDHVVSSSALYGGTVNQLKHLFRKMNVELSWVDPDDPEAWRAAVRPNTKAFYGE
                     TIGNPGGNVLDIETVAAIAHEHGLPLIVDNTFATPYLCRPIEWGADIVVHSATKFIGGH
                     GTSIGGVVVEAGTFDYSNGRFPVIADPSPAYHGLKFHETFGEYGYLMKLRAETLRDLGA
                     AMSPFNAFLFLQGLETLSLRMDRHVDNALTVAEFLQTHELASKVSYSGLADSKYKALVE
                     KYLPRGAGAVFSFECAGGREGGQAFIRGTTLWSHLANVGDAKSLIIHPASTTHRQLGDA
                     ELAATGVGAGTIRLSVGVESVADLIWDLEQGFAHVEKA"
     aSDomain        complement(12025..12534)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AW272_RS02810_Aminotran_1_2.1"
                     /evalue="3.00E-11"
                     /label="AW272_RS02810_Aminotran_1_2.1"
                     /locus_tag="AW272_RS02810"
                     /protein_end="231"
                     /protein_start="61"
                     /score="34.9"
                     /tool="antismash"
                     /translation="GNTYSRIMNPTTAVFEERMANLEGGSGAVAFASGIAAQAAALFTL
                     LEPGDHVVSSSALYGGTVNQLKHLFRKMNVELSWVDPDDPEAWRAAVRPNTKAFYGETI
                     GNPGGNVLDIETVAAIAHEHGLPLIVDNTFATPYLCRPIEWGADIVVHSATKFIGGHGT
                     SIGGVVV"
     gene            complement(12714..13898)
                     /locus_tag="AW272_RS02815"
     CDS             complement(12714..13898)
                     /EC_number="2.3.1.31"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (45-375). E-value:
                     1.2e-26. Score: 85.7. Matches aSDomain:
                     nrpspksdomains_AW272_RS02815_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546080.1"
                     /locus_tag="AW272_RS02815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="homoserine O-acetyltransferase"
                     /protein_id="WP_066360776.1"
                     /sec_met_domain="PF00561 (E-value: 2.4e-37, bitscore:
                     124.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSIGFVETHYLDLPGPIRLDSGRELRDVRVAYETYGTLSPERDN
                     VILVCHALSGNAHAAGSAKTAPEASARDGFGAEDRDGAQGKGLGWWDGMIGPGKAFDTD
                     QYFVVCTNLLGGCSGTTGPSTIDPATGRPYGSDFPVVTVADMVRTERAFLDELGIERLA
                     VIAGGSLGGMQALEWAVQYPGQVDAIVVIASTHALHPQGLAWNAIARESIMRDPDWQGG
                     HYYGTGRKPDAGMGVARMVGHVTYLSGPALTDKFGRRLQFADDIRHTIVEPEFEVESYL
                     RHQADSFVKRFDANTYLYISRALTYFDLAREHGGGSLEKALENIRARTLLISFSSDWLY
                     PPEASDEIAEALTNLGKPVENHLIDAPYGHDCFLLEEARQTPLIREFLARKIAS"
     aSDomain        complement(12774..13763)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AW272_RS02815_Abhydrolase_1.1"
                     /evalue="1.20E-26"
                     /label="AW272_RS02815_Abhydrolase_1.1"
                     /locus_tag="AW272_RS02815"
                     /protein_end="375"
                     /protein_start="45"
                     /score="85.7"
                     /tool="antismash"
                     /translation="VILVCHALSGNAHAAGSAKTAPEASARDGFGAEDRDGAQGKGLGW
                     WDGMIGPGKAFDTDQYFVVCTNLLGGCSGTTGPSTIDPATGRPYGSDFPVVTVADMVRT
                     ERAFLDELGIERLAVIAGGSLGGMQALEWAVQYPGQVDAIVVIASTHALHPQGLAWNAI
                     ARESIMRDPDWQGGHYYGTGRKPDAGMGVARMVGHVTYLSGPALTDKFGRRLQFADDIR
                     HTIVEPEFEVESYLRHQADSFVKRFDANTYLYISRALTYFDLAREHGGGSLEKALENIR
                     ARTLLISFSSDWLYPPEASDEIAEALTNLGKPVENHLIDAPYGHDCFLL"
     misc_feature    complement(13907..13920)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.8"
                     /tool="antismash"
     gene            13945..14484
                     /locus_tag="AW272_RS44790"
     CDS             13945..14484
                     /EC_number="1.11.1.-"
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546081.1"
                     /locus_tag="AW272_RS44790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="OsmC family protein"
                     /protein_id="WP_066360778.1"
                     /transl_table=11
                     /translation="MTNGVNVQALLDAREVLKGAPEAAQFTWRASSKWQHGVHSTTKIE
                     KFFGLGQEQTHKHESVFEADHPAIFAAEDNGITPIEYLLVGLASCLTAGIASVAQNRGI
                     KLNSVEASVEGGHDIRGILGADADVRNGFNDIKVTFSIDADASPADIEALVAQSQKRSA
                     VFDALTNPTNVTVEVA"
     gene            14487..15677
                     /locus_tag="AW272_RS02825"
     CDS             14487..15677
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546082.1"
                     /locus_tag="AW272_RS02825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_066360782.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1e-14, bitscore:
                     50.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHVTTVVIGAGHAGLAASHFLRAASIDHVVLERGEVANSWRHERW
                     DSLRLLTPNWLNRLPGASYEGPDPDGYADMAEVVDFLERSAKDVPVRTGVAVTSVRRSD
                     GGYSLTTSQGPIEARTVIIASGACNVASVPGLAAAVPSSVEQVTPFDYRTPSRLPDGGV
                     LVVGASATGVQLAAEIQRSGRPVVLSAGEHVRMPRVYEGRDVLWWMHHSGIWSQRYDEV
                     DDLTRARRLPSPQLAGASTLDLNVLTSLGVELVGRLSAIRDGAALFSGGLRNVAALADL
                     KMNRLLDTFDEWAGTAPGERFQPTRVPDSSRWRLDLTSGEIRSIVWATGFRPDYSWLDV
                     PVVDAKGSLVHDGGVVGDGLYALGLPVLRRRRSTFICGIEDDAREVVDQLRLDLAG"
     gene            complement(15830..16402)
                     /locus_tag="AW272_RS02830"
     CDS             complement(15830..16402)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AW272_RS02830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157518225.1"
                     /transl_table=11
                     /translation="MHKLLGALALTTGLLVAPTAAQAAPATKGPCWAGSWTVTKATAKV
                     VGKRHRFFAEGGAGIKADFTRAGKYVVARYDFRESEPLTGGATFVMDGVETFTYTFGGY
                     KKYTHGKIVLKPRTGDFGATLERSGGGKGFSGLLRKAVAHNEDLGAIPRKGTYTCVPGK
                     SLRINTHGKSGRTVITIKWELTRPPVA"
     misc_feature    complement(16391..16393)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16404..16421)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.9"
                     /tool="antismash"
     misc_feature    16450..16466
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.24"
                     /tool="antismash"
     misc_feature    complement(16458..16471)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.82"
                     /tool="antismash"
     gene            16532..17236
                     /gene="nth"
                     /locus_tag="AW272_RS02835"
     CDS             16532..17236
                     /EC_number="4.2.99.18"
                     /GO_function="GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="nth"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012887241.1"
                     /locus_tag="AW272_RS02835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="endonuclease III"
                     /protein_id="WP_083957868.1"
                     /transl_table=11
                     /translation="MAKETRLGLVRRARKMNRILAETYPDAHCELNFANAFQLLVATVL
                     SAQTTDVRVNLTTPALFAKYPTPDDMAVADPEDMEAILRPTGFFRAKTKSVIGLSIAIR
                     DRFGGEVPRKMADLVTLPGVGRKTANVVLGNAFGVPGLTVDTHFQRLVKRFGWIEGELD
                     PVKIEQEIALLIPKNEWTVFSHRIIWHGRRICIARKPACGACPLADLCPSYGTGPTDPE
                     LASKLVRSGPFS"
     misc_feature    complement(16573..16588)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.85"
                     /tool="antismash"
     gene            17274..17918
                     /locus_tag="AW272_RS02840"
     CDS             17274..17918
                     /EC_number="3.6.1.55"
                     /GO_component="GO:0005777 - peroxisome [Evidence IEA]"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0003986 - acetyl-CoA hydrolase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008413 - 8-oxo-7,8-dihydroguanosine
                     triphosphate pyrophosphatase activity [Evidence IEA]"
                     /GO_function="GO:0010945 - coenzyme A diphosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030145 - manganese ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0035539 - 8-oxo-7,8-dihydrodeoxyguanosine
                     triphosphate pyrophosphatase activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /GO_process="GO:0015938 - coenzyme A catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012887242.1"
                     /locus_tag="AW272_RS02840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CoA pyrophosphatase"
                     /protein_id="WP_066360786.1"
                     /transl_table=11
                     /translation="MTDVPAWITDVAERAGRTPVPPGLRPPREGGRRAAVLLLFGDGPN
                     GPDILLIQRSSRGRTHAGQPAFPGGGVDPDDDGPVGAALREAAEETGVDPEGVAVVGTM
                     PELYVRHSDNRVTPVIGWWHTPCAVHAASPDEVESVERVSIAELVDPANRLRLRHSSGY
                     IGPAFRVRGLLVWGFTAGVLDGVLSTCGFEVPWDRSRIEDLPPDVVNLAAR"
     gene            complement(17868..18413)
                     /locus_tag="AW272_RS02845"
     CDS             complement(17868..18413)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012887243.1"
                     /locus_tag="AW272_RS02845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="WP_066360790.1"
                     /transl_table=11
                     /translation="MGDPVEELIQTALADGDPDGPTRWDAIAALQQRGDLETFTAARRL
                     CAADTAAERVLGVDILGELGRDRPFADKTLPVLRFLAASETETRVLYSVLIAFGHLRDP
                     RALPSVIELASHPETTVRYGAAYALPNVIGRPADPSGVAALRRLAADRDDDVADWATLG
                     LALTGGEVHDVRGQVLDP"
     gene            18525..19715
                     /locus_tag="AW272_RS02850"
     CDS             18525..19715
                     /EC_number="3.4.21.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013130472.1"
                     /locus_tag="AW272_RS02850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarP family serine protease"
                     /protein_id="WP_245657167.1"
                     /transl_table=11
                     /translation="MQGDLLDLILIGLILAFAVSGYRQGFIIGAFSFVGFAGGALVGMF
                     IAPPIAGALVNGETERALLAIVIVFLAATVGQFASSTIGAVVRSHVTWEPARLIDAFGG
                     SVASGLSVLVFAWLIGSLIISMNFPLPKQQVNDSLLLKTVDQAMPEAARDLTRGFRDFV
                     DASPWPEVFADIGGAQFVDVPAPDESIINDPQLARARRAIVKVQGTAPTCRKRIEGTGF
                     AYAPHRIMTNAHVVAGVSQDLRVTDYRGASHDARVVLYNPDRDIAVLYVESLDVNPLKF
                     DMAAESKDDAIIAGYPKGHGFTIKPARIRVKQPAESYDIYNRHTVDREVYAIRGEVQPG
                     NSGGPLLAPDGRVFGVIFAAATDQKDTGYALTAEEVRTDAEDGSAAIARVDTQECD"
     gene            complement(19719..20678)
                     /locus_tag="AW272_RS02855"
     CDS             complement(19719..20678)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890843.1"
                     /locus_tag="AW272_RS02855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_066360792.1"
                     /transl_table=11
                     /translation="MGWWQVNADTLAGSRFVLSPLAETTACMFALGRTLPAHPGEKPWW
                     DQHADRFKTRLTRDPLDEFLIRAATGAEWIADFLVPTPAGTGEPTFAEEVATVRDTPAG
                     VVYADLEVSLGRMLPGPLRRSDLAERAASLLEWVWTETVEPTWDRRRRILEADIIGRIG
                     RLSMGGWEAALNDMRPGMRWLGESRLQINTTSNPPRDLATARLMFVPVTPRHGWVSWEQ
                     PHRYAVIYPASGVLTDVREVSGPLGRLLGSARATVLVLLDTPKSTTQLVALTGQGLGSV
                     GRHLKVLLDAGLVERRRAGKSVLYYRSRTGDAVVTSAE"
ORIGIN
        1 ccgcgcgggt cgccgatgct gacggcggag gcgaggtcgg gggtgtagcc ggcgaaccag
       61 gcggcggtgt agccgtcggt ggtgccggtc ttgccggccg cgtcgcggcc gatgccgccg
      121 accccggtca tggtgccctt ggtaaagacg ccgctgagga tcgagctggc cgcgtcggcg
      181 acctcctcgt cgagcacctg gtcgcagtcg ggcttgtagt tggtggcctt gccctcgcgg
      241 tcgacgatct cggtgatgac gatcggcgcg cagtacttgc cgcgggcgcc gatggtggcg
      301 taggcgttgg cgaccgtcac cgggtccatc tcgttgacgc cgagggtgaa ggtcgggacc
      361 tcgcggaggt cggcgccgtc ggcccggtgg atgcccagct tcttggccat cttgacgacc
      421 ttgcagaggc cgacgtgctc ttcgagcttc atgaagaacg tgttcaccga gccccaggtg
      481 ccggtctgga gggtgttgaa cccgccggcg ccctcactgg agttgaacac ctggtgggtc
      541 tcgccggtcc ggttgccctc gcagtcgcgg aacggcgaca gcgagttggt cgggatgtcg
      601 taggtcttgc cggtggcgaa cccgtcgttc agcttcatgc cctcgtcgag ggcggtcagc
      661 agggtgatca ccttgaacgt ggagcccgcc tggaagccgg aaccgccgcc gtgggagcgg
      721 ttggccgcca ggttgtagct catctcgttc ttcttcttgt tgtcgccgaa cttccggctg
      781 gcggccagcg ccttgatcga acccgtgccc ggttcgacca gcgcctgggc cgcgacctga
      841 tcgtcgctcg cgtagacgtg cttcttgatc gccgcgtcgg cggccttctg catcttcgtg
      901 tcgagcgtgg tgcggatcgt caggccaccg cggttcagga agtcgcgccg ggccttctgc
      961 gtcttgccga agtcggtgtt gttcaggatg tcgttctgca cgtagaggca gaagtagggg
     1021 taggagctgt cctcacagcc gcccggcatc ttctcgccct tgtagccgag cttctccttc
     1081 ttggcctcgg ccgcctgggc gagcgagatc ttgcccagct cggccatccg gtcgagcacg
     1141 gtgttgcggc ggcccagcag ccgctcgcgg aactccttgc cccggcccgg gtcggtctgg
     1201 ctcgggttct gcaccgcgcc ggcgagcgtc gccgcctcgt gcaggtcgag ctcggaggcg
     1261 tgcttgtcga agaagcgctt ggacgccgcc tcgatgccgt aggcgccgtc accgaagtag
     1321 gagatgttca ggtaacgatt gaggatctcg gccttggagt acttcttctc gatggccatg
     1381 gcgtagcgga tctcgttcaa tttccgcgtg tacgtcgcct cgatcgcctt cagctgatct
     1441 tcctcggtct cggccgagtt gaagatgacc agcttcacgt actgctgggt gatcgaggag
     1501 ccaccctgca cgacgccgcc gccgaagatg ttcttggtga gcgcgcggac cgttccctcg
     1561 atgtcgaggg cgccgtgctc gtagaaccgg aagtcctcga tcgcgatgat cgcctgctgc
     1621 atgaccggcg cgattttgct cagcggcacg gattcgcggt tctggaagta gaactgcgcg
     1681 atctgcttgc cggccgagtc gagcagcacg gtcttctcgg gcagcggggg ctcgttgagc
     1741 tcctccgcct cgatgcgcag cgactcgacg cctgacttgg cgctgaaccc ggctccgccc
     1801 acggccggca gtccgaccgc cgcggccagc acaccggcca tggcagcggc cacgatgagc
     1861 ttgacgaggg tcaagatcgc gttcccgaaa cgggctttgc ctgaagcttg cacgaggcta
     1921 agcgtacttc ggagcaaggg gagattcggt accaaacgca ccacgtcgca ttacccgcgc
     1981 ttgagatgac tagtcatctc cggacaccgc cccccgccaa atttggtccc tgcgggtctg
     2041 tccattcgga tgcggagtct catacgttct cctctgcggc aactgaattt aggaggctcg
     2101 gcgaccgcgc ccgtcggccc cagaagtcac gactgaccac ctaaggggag tggggtcgaa
     2161 aaatgtggat cacggattgg acctcccgtg ccgcctgtcg aggtgcggat cctgacgctc
     2221 tgttcgttca gggcgccgca caaaaccggg cgaagttgat ctgtcgagga tgccctgtcc
     2281 gtaccgaatg cctcgccgat gcgctggaca atcgcatcga gttcggggtt tggggcggaa
     2341 tgaccgaacg ggaaaggcgc gccctcctgc gccgtcggcc cgacgtcgac tcctggcgcg
     2401 acctgctgga gctggcgaag gaagaatacg aacgcaccaa tgagctgatc gccggctgac
     2461 cctcagcgct tggccaggag ttccccgatc tcacgcaatc cgtcgagatc gtgaacatcc
     2521 tgtgacatcg cgggcacctg ggtggccggc acagtggggt gggccgaggc gaaacgttcc
     2581 tgctcccggt gctcgcgagc ggcgagttgc atccgtccgg cgtgcagtct cagcacggcg
     2641 gcggtcagct cgtgttcacc acgtgactcc aggtcttccg cggcggcggt gctccgcgcc
     2701 gcggacagac cgggagccgg tgagcggtgc acccggttga ccaccaggcc ggccagcggc
     2761 atccgctcct cggcgagtcg ctccacgaaa taggaggctt cccgcatcgc gtcacgctcc
     2821 ggcgtggcca ccacgacgaa cgcggtgccg ggagcctgca gcagctggta ggtctgctcc
     2881 gcccgctgac ggaatccacc gaagacggcg tccagcgcgg agacgaacgt ctggatgtcc
     2941 ttcagcacct gggcgccgag caccttcgtc agcactccgg ccacgaggcc gaacccggcg
     3001 ttgaggatct tgaacgcgct gcgtccgccc gccttggcgg gcgccatcag cagccggatc
     3061 agttttccgt cgaggaagcg cccgaggcgt tcgggcgcgt cgaggaagtc gagcgccgac
     3121 cgtgacggcg gcgtgtcgac gatgatcaga tcccactcgc ccgaccgccg gagctggccg
     3181 agcttctcca tggccatgta ttcctgggtg ccggagaaac tcgacgagag cgactggtag
     3241 aaggggttcg tcaggatctg gcgggcccgc tcggggtcgg cgtgggcctc gatgatctcg
     3301 tcgaaggtcc gcttcatgtc gagcatcatg gcgaacagct cgccgtcggc ccccgccacc
     3361 ttgcgcgggg tgttgtcgag cgaggtcagc cccatcgact gggccagccg cctcgccggg
     3421 tcgaccgtga gcaccaccac gttgcggccg cgttcggccg cccgcagccc cagggccgcc
     3481 gccgtggtcg tcttgccgac gccgcccgac ccgcagcaca ccacgatccg ggtgcccggg
     3541 tcgtcgatga tgccgtcgag atcaagctcg ggcgtggtca tgcggctcct tgcgtgcgga
     3601 tcgcttcggc gagttcgtag aggcccgcga ggtcggcgcc gtccgccagc aggggcagtt
     3661 catatcgtgg caccccgacg gtctccagcg cgtcgcgctc ggttctttcg agctcggccc
     3721 gccgctgctg ctcgacgacc tcgccgccga gggcctcggc gatgaccgcc gcgttgccgt
     3781 cgtcgcccag cccggccgcc ttcacgccca tggccagttc ggccaggtcg aaagggcctt
     3841 cgaggacggg gtcgacggtc cggaccatgt tgacgaagat cccgcccacg ggcagtttgg
     3901 ccgcgtgtag ctcggtgacg ccgtcgaggg tctcctggac gggcatctcc tccagcaggg
     3961 tgacgaagtg gacggccgtc tcgggcgagg ccatcactcc ccgcaccatg tcggcatggg
     4021 cgcgtaccgg gccgactctc gccaggccgg ccacctcttg ggtgacgttg aggaaacggc
     4081 tgacccggcc ggtcggcggg gcgtccatga cgacggtgtc gtacaccctc ttgccggttc
     4141 tgtcgcgccg ccggaccgcc tcgctggtct tgcccgtgac caggacgtca cggaggcccg
     4201 gggcgatcgt ggtggcgaag tcgaccactc ccatcttggt cagcgccttg cccatgcgct
     4261 tgagcccgta gaacatctcg aggtattcga gcatcgcctc ttcggggtcg atcgccagag
     4321 cgtggacgtc accgcctccc ggagccaccg cgatgcggcg ctcctcgtag ggaagcggtg
     4381 gaaggtcgaa gacctgcgcg atgccctggc ggccctccac ctccacgagc agcaccttgc
     4441 ggccgccggc cgcgagtgcc agggcgagtg cggcggccac agtggtcttg ccggtaccgc
     4501 ccttgccggt cacgacatgg agacgcactc cgtcccagtc ggtgtcgcga gatctcacac
     4561 ccgtgaggct acccaaaggg cttttcccga tacgccgagg cctgctgggt atcgataacc
     4621 ttccgccatg acgaagtggg agtacgtgac cgtgccgctg ctgacgcacg cgaccaagca
     4681 gatcctcgac aactggggtg aggacggctg ggagctcgtg gccgtcatcc ccggcccgaa
     4741 ccccgagcag ctcgtggcct acatgaagcg ggccaaggcg tgagttcccc cgaagaccgc
     4801 ctggcggccc tggggctgtc gctgcccgac gtggtggccc cgctggcggc ctacgtcccg
     4861 gcggtccgct cgggcgctca cgtgtacacc tcgggccagc tgcccatcgc cgccggggag
     4921 ctgctcaaga ccggcaaggt cggcgcggag gtcacccccg aggaggccta cgagctggcg
     4981 aagctctgcg ccctgaacgc catcgcggcg ctcaggtccg tcgtcgacct cgaccaggtc
     5041 gtcgggatcg tgaaggtcgt cggtttcgtc gcctcggctc ctgacttcac cggccagccg
     5101 caggtcgtga acggcgccag cgagctcctc ggcgaggtct tccagggtgc ccacgcccgc
     5161 agcgcggtcg gcgtggccgt gttgcccaga gatgccccgg tcgaggtgga actgatcgcc
     5221 gagatccgtt agatctacac tcggggcgtg gacattccgc tgccgggcga gctgggtgaa
     5281 cgggcgcgtg acctgctggc cgggcggctc gtcccggtcc cgccccgggc cgccgccacg
     5341 gtggccctgc tgcgggagcc gcctctggag gtctacctgc tccggcgggc ggcgaccatg
     5401 gccttcgcgg ccggcgccta cgtctttccc gggggctccg tcgatccccg ggacgccggc
     5461 cacgacatcg gctgggccgg gccttcgccc gccgaatggg ccgccgcgct gaacgccgac
     5521 gaggacacgg cgcggggcct cgtctgcgcg gcggtgcgcg agaccttcga ggagagcggt
     5581 gtcctgctgg ccggagatcc ggtcgacgac acgaccatgt gggaggccga gcggctggcc
     5641 ctgatcggca gggagctctc gttcgccgat ttcctggcca cgaacggcct ggtactcagg
     5701 tctgacctgc tgaaaccgtg ggcccactgg atcacgccgg agatcgagac ccgccggttc
     5761 gacacccgct tcttcgtggc ggcgctgccc tcgggccagc ggaccaggga tgtgggcggc
     5821 gaggccgaca cggtcgtctg gcacagcccc gccgaggccc tcgcctccgg atatttcctg
     5881 atgccgccca cgctgcacac gttgaccatg ctgacggcct ccgagacgat cgcggacgtg
     5941 ttcgccgccg accccaagat caccacagtg atgcccgccc cggtcgagag gaacggccag
     6001 atggtcctga ccaccgaagg acagatctga tgagcgggct cccgctgccg atcgacggtt
     6061 cgggaacccc gaccgcgacc aacgtgctgg cccccaacgc gtccccgatg actctcgacg
     6121 ggaccaacac ctgggtgatc ggccgtggcg agtcggtcgc ggtggtcgac cccggtcccg
     6181 acgacgaggc ccacctttcg acggtggtct ccagactggg cgaccggaac gtggaggtca
     6241 tcctcctcac ccacggccac gaagatcaca gcggcggagc ccggcggttc gccgaactgg
     6301 tgaattctcc ggtacgagcc ctcgaccgca cccacgtgct gggcgaagag ggcctggagg
     6361 acggcgacgc cctgacggtc ggcggcgtgg agatccgggt gatcggcacc cccggccact
     6421 cgttcgactc cctgtgcttc tggctcccgg acgacagcgc cctgctgacc ggcgacacca
     6481 tcctgggccg gggatcgacg gtcatcgcgc ccgacggcga cctggccgac tacctgcgca
     6541 gcctcgacaa gctccgcgcc atggccgaac tggccgaggc cgaggccctg ctcccgggcc
     6601 acggcccgat cctggccgac cccgtcggca agctcgacga gtacatgacc caccgcaggc
     6661 agcgcctcga ccagatccgc caggcgatca gggacggcgc ccgcgacgcc ggggagatcg
     6721 tggaaatggt ctacgcggac gtcccgaagg atctctggcc ggcggcgcgg atgtcggtgg
     6781 ccgcgcagct caactacctg aagacccgct gaccttgcga gaccacctca tcgacgtggt
     6841 gcggacggtg atcggggaga tccgcccgaa gctggtcgcc gcggccctgt ccggtgatcg
     6901 ctccgagcac cggaacctcc gccacgcgga caacttcctg tcctcgcacg atctctggct
     6961 gcaccggcgc taccgggaac tcctcgccga gcgtttcgcg tccttcgtct acgcgtcgga
     7021 ggaaggcgac cccgaagtgg tcggccccga cccggatccg gacctctgcg ttctcgtcga
     7081 cccgctcgac acgagtgaac tggccgtgcg cggcctgaac ggctacacgc agatcctggt
     7141 ctattcgcga gcgctgggcc gccctctcgc ggcggcggtc ggcgacctct tccaccattt
     7201 ccaggtctat gtggcggccg agggcgaggc gcatgtcctg acccaagacg gagaccggca
     7261 tcctttgcgc gtggacggaa tgtccgtgcc gctccgcgat tcgctggtga cgaatttcct
     7321 gatgaagccg gccgaccgtt tcggcccgct ggcccggcag acacggctgc tggcggcgct
     7381 cagtgagggc cggggacgaa taggcctcga tttcggctcc atcggcctgt gccacgtcgc
     7441 ggcgggcttc accgacgccg tggtcgaatt cgccaagggt ttcgcgatct gggacctggc
     7501 tcccggcgcg tacatcctga attgcgccgg gggcggcgtc tatgacctga cgggagcccc
     7561 gatcagcctc gacggccttc tcaccgacat cggcgcggcc atgagcacgc ggcggaaatt
     7621 cgtcgcgacc agagacgaaa cgctggcgcg cgacatcctc cgcctcatcg gctagcgcga
     7681 gcggttgtag agacgctcca tgtccatgat cacaacggcc ttggcctcga tgcgcagcca
     7741 gccacggccc gcgaagtcgg ccagcgcctt gttcacggtc tcccgggacg ccccgacgag
     7801 ctgggccagt tcttcctgcg tcaggtcgtg gtggacccgg atgccgtctt cgaccttctg
     7861 cccgaaccgc tcggccaggt cgaggagcgc cttcgcgacc cgtccgggca cgtcggtgaa
     7921 caccaggtcg gccagcacgt cgttggtccg ccgcagccgc tgagccaggg cccgcagcag
     7981 gtggagagcc acctcgggcc gcccggtgag ccagggccgc aggtcgtcgt gggacagacc
     8041 ggccagcttc acatcggtca gcgcgatggc cgaggccgtg cgcgggcgcg gatcgaacag
     8101 cgagagctcg ccgaacatct cggacggccc caggaccgac aggaggttct cccgcccgtc
     8161 ggacgccgtg cgggccagct tgatcttgcc ctcgaggacc acgtagaggg tggccccggt
     8221 ctcgttttca ctgaacaggg tctgaccctt ggtcagagtc acttcggtga tgcttgtgcg
     8281 gagggccgcg gcgctctcac ggtcgagcgc ggagaagagg ggggccctgc tcaagacttc
     8341 ttcggtgctc atgcctgcct cccaacttca ttcgcgatcg tagccattgt ggcctatgcc
     8401 ccgccttccg catcacctgg accaccagaa agcagacgtc ggacggctgt cgcgacgtag
     8461 tgagcccgct cgtcgggcgt gacggtctcg accacggcgg cggattcggg gttgacggcg
     8521 gtccacacca aggagagatg gagcaccagg ttcatgagga tgccgggcgg gaactcggtg
     8581 gtcaggatcc cctcggcctg ggccttggcg atgacctcga ccttgtgccg catgctctcc
     8641 acggccagcg gcaccggcgg atcgccggcc cgctccagac gctgccaggt cgccagccgg
     8701 gcgacctgcg ggtgggcctc atagcctctg gccagcgcgg cggcgtagcc cgggaggtcg
     8761 tgggcgtcga tcggggtctc ccgcacgatc cgctcgacga tcccgttgaa gacggcgtcg
     8821 aagagctgat ccttgctgcc gaagtagtgg tagatctgcg ccttgttggt gccggccacc
     8881 gccgcgacgc ggtcgacccg ggccccggcg atgccgtatt cggcgaactc ctccagggcg
     8941 gcgtcgagca ggcgctgtcg ggtggcgtcg gctttgccag gcatgcccca agactatttt
     9001 ctaaccggtt agttgacaac tcggagaagc cgtacctact gtttcaacta accagttagt
     9061 cgaaaaatta cgcgaggttc ccatgatctg gttcgtcacc ggtagctccc gggggctcgg
     9121 ccgcgagatc gtcctggccg cgctcgaacg cggcgacagc gtcgccgcca cggcccgcac
     9181 acccgcccag ctcgacgaca tgtcccagaa gtacggcgac cgcatcctcg ccctgcccct
     9241 cgacgtcacc gacgcggaag cggtcgaaga tgccgtggcc acggcggtgg aggcgttcgg
     9301 ctcgatcgac gtcgtggtca acaacgccgg ctgggccgac atgtcggcgt tcgaggacac
     9361 cccgatcgac aacttccggg ctcaggtcga gaccaacttc ttcggcgtcg tcaacgtgac
     9421 caagtcggtc gtgccggtcc tgcggcggca ggggcacggc tcgctgatct cggtctcctc
     9481 catcggcggc cgtctcggca cgccgggcct ggcggcctac caggcctcca aatgggccgt
     9541 gaacggcttc accgaggtga tcgcgcagga actcaccccg ctgggcatca aggtgaccac
     9601 gatcgagccg ggcggcatga ccaccgactg gggcggttcg tcgatgacga tcccgccgat
     9661 ctccgagccc taccagcaga gcgtcggggc gatggtgcgg atcctgcggc agggcgacca
     9721 caagccgctc ggcgaccccg cgagggtcgc gcaggtgatc gtccagatcg tcgagatgga
     9781 caatccgccg gtccggctgc tgctcggctc cgacgcgctc aacggcgccc agtacgccgc
     9841 gcacaccacg gcggagcgcg atgccacgta cacggaactg agccgttcca ccgaccgcga
     9901 cgacgccacc gcccaggagc gtgatcctct gggtcaagca ttctccacaa tggccgatgg
     9961 cgaagcggcg gagtgaggcc agtcgtgtat cggtagccgg gtgaccgact cgatgaccgt
    10021 ccgcgacgtc ctcaacgcga cccgcgaact gatcgaaccc gcccaccggg ccgcgatcga
    10081 ccggctctcc ccggagctgc gccacgtcgc gggctaccac atcggctggt gggacgaaga
    10141 gggccgcgag ctcatcggcg gccaggggcg gttcgtccgg cccgcgctgg cgctggggtg
    10201 cgcgcgggcg gccggggggc acgcctccga cgcggtgccg atggcggtcg cgaccgagct
    10261 ggtcaacgac ttctcgctgc tgcacgacga cgtgatcgac ggcgacgaca tccggcggga
    10321 gcgcccggcc gcctgggcgg tcttcgggct cagcgaggcc ctgctcaccg gcgacgccct
    10381 gctggcggtc gcgatggcgc tggtcgggcc cgcgggggtg cgcaccctcg ccgacgcgct
    10441 gctcgacctg tgccacggcc aggccagcga tctggcgttc gtcgaccggc ccgaggtcac
    10501 cctggccgag tgcatgacga tggccgagaa caagaccggc gcgctgctcg gggcggcctg
    10561 cgagctgggc gcgctggccg ggggaacggg cgacgtccag cgcttccggg agttcggcac
    10621 ccgcctcggg ctggccttcc ggctcaccga cgacctgcgg agactggtcg ccgacctggc
    10681 ctgccgccgt aagtcgctgc cggtcgtcgc cgcgctcgaa tcccgtacgc ctgccgccgc
    10741 ccgcctggcc gaagcgctcc acgaccaggc cgaccccgag gtccaggccg agctggtcga
    10801 ggagacgggc gccagagaat gggcgctccg ggaggccgac cgtcaggtcg agctcgcttt
    10861 cgcggcgctc ggccaggggg ccaccccgga gctgcggctg ctggccgacc tcagcgtcgg
    10921 ccggacccgg taggggctag tggatgccgg tgcggaccga ggtgatccgc ccggtgttga
    10981 agcccagcca gtgcatgcgg cccatgtaac gggcgtgctc gatcttcatg cagcggtcca
    11041 tgatcaccgt gaggccgccc tcttcggcga tgcgggcgcc ctcttcactg atgacgccga
    11101 actggagcca cagcgccccg gcgccgatct cgaccgcctc acgggcgatg ccggggacgg
    11161 cgtcgggcgc gcggaagacg ttcaccacgt cgatcttgac ggggatgtcg gacaggctcg
    11221 ggtaggaggt ctcgccgagg atctccttct cgcgcgggtt gaccgggatc atccggtagc
    11281 cgtgccgctt gaggtagaag ccgacgaagt tgctggcccg cagctcgttg cccgacaggc
    11341 ccacgaccgc gacggtcttg gcggtgttga gcacccgctg gatgtcctgc ggctcttgat
    11401 acttcatgcc ttctccacgt gagcgaagcc ctgctcgaga tcccagatca ggtcggccac
    11461 cgactcgacg ccgaccgaca ggcggatggt gccggcgccg accccggtgg cggccagttc
    11521 ggcgtcgccg agctgacggt gggtggtgct ggccgggtgg atgatcaggc tcttggcgtc
    11581 gccgacgttg gccaggtggg accagagcgt cgtaccgcgg atgaaggcct ggccgccctc
    11641 gcggccgccg gcgcactcga aggagaacac cgcgcccgcg ccgcgcggca ggtacttctc
    11701 caccagcgcc ttgtacttgc tgtcggccag ccccgagtag ctcaccttcg aggccagctc
    11761 gtgggtctgg aggaactccg cgaccgtgag cgcgttgtcg acgtggcggt ccatgcgcag
    11821 cgacagcgtc tcgaggccct ggaggaacag gaacgcgttg aacggcgaca tcgccgcgcc
    11881 caggtcgcgc agggtctcgg cgcgcagctt catcaggtag ccgtattcgc cgaaggtctc
    11941 gtggaacttc aggccgtggt aggccggaga cgggtcggcg atcaccggga agcggccgtt
    12001 ggaatagtcg aacgtgccgg cctcgacgac cacgccgccg atgctggtgc cgtggccgcc
    12061 gatgaacttg gtcgcggagt gcacgacgat gtcggcgccc cactcgatcg gccggcacag
    12121 atagggcgtc gcgaacgtgt tgtcgacgat cagcggcagg ccgtgctcgt gggcgatggc
    12181 cgcgacggtc tcgatgtcca ggacgttgcc gccggggttg ccgatcgtct cgccgtagaa
    12241 ggccttggtg ttcggccgga ccgccgcgcg ccaggcctcg gggtcgtcgg ggtcgaccca
    12301 gctcagctcg acgttcatct tgcggaacag gtgcttgagc tggttgaccg tgccgccgta
    12361 gagggccgag gaggacacca cgtggtcgcc gggctccagc agcgtgaaca gcgccgcggc
    12421 ctgggcggcg atgccgctgg cgaaggccac cgcgccgctg ccgccctcga ggttggccat
    12481 ccgctcctcg aacaccgccg tggtcgggtt catgatgcgg gagtaggtgt tgccgtactc
    12541 ctggaggttg aagtaggccg ccgccgactc ggggtcttcg aagacgtaac tggtggtctg
    12601 gaagatgggc accgcgcggg cgccggtgtt cgggtcgggc cgctgtcccg cgtggagctg
    12661 gcgggtctcg aacccgaact cccgggattc ttcggtacga aatggtctgt cgctcacgaa
    12721 gctatcttcc tcgccagaaa ctcacggatg agaggggtct gccgtgcttc ctccagcagg
    12781 aagcagtcat gaccatacgg tgcgtcgatg aggtggttct ccaccggttt gcccaggtta
    12841 gtcagcgcct cggcgatctc gtccgacgcc tccggcggat agagccagtc ggagctgaac
    12901 gagatgagca gcgtccgcgc ccggatgttc tccagcgcct tctccagcga accgccgccg
    12961 tgctccctgg ccaggtcgaa gtaggtcagc gcgcgggaga tgtagagata ggtgttggcg
    13021 tcgaaccgct tcacgaagga gtcggcctgg tggcgcaggt agctctcgac ctcgaactcc
    13081 ggctcgacga tcgtgtggcg gatgtcgtcg gcgaactgga gccgccggcc gaacttgtcg
    13141 gtcagggccg ggccggacag ataggtcacg tggccgacca tgcgggccac gcccatgccg
    13201 gcgtcgggct tgcggccggt gccgtagtag tggccgccct gccagtcggg gtcgcgcatg
    13261 atggactcgc gggcgatcgc gttccacgcc agaccctggg ggtggagggc gtgggtggag
    13321 gcgatgacca ctatggcgtc cacctgaccg ggatactgga ccgcccattc gagggcctgc
    13381 atcccgccca gcgaacctcc cgcgatcacc gcgagacgct cgatgccgag ctcgtccaag
    13441 aaggcgcgtt cggtgcggac catatccgcc acggtgacga ccgggaagtc ggagccatag
    13501 gggcgcccgg tggcgggatc aatggtggac gggcccgtcg tgccgctgca gccgccaagt
    13561 agattcgtac agacaacgaa atattggtcg gtgtcgaaag cctttccggg cccgatcatc
    13621 ccgtcccacc aacccagccc tttcccctgc gcgccgtcgc ggtcttcggc gccgaagccg
    13681 tcgcgggcgc tcgcctcggg agcggttttc gcggaaccgg ccgcatgggc gttgccgctc
    13741 agggcgtggc agacgaggat gacgttgtcc ctctcggggg agagggtgcc gtaggtctcg
    13801 taggccacgc ggacgtcgcg cagctcccgc ccgctgtcga ggcgtatcgg accaggcagg
    13861 tcgaggtagt gagtttcaac gaaacctatg gagcccatgg gatctattgt attgtcaagt
    13921 taacatgtag gaaatgaggg gatcatgacc aacggagtga acgtccaggc gctgctcgac
    13981 gcccgcgagg ttctcaaggg tgcgcccgag gcggcccagt tcacgtggcg ggccagctcc
    14041 aagtggcagc acggcgtcca cagcaccacc aagatcgaga agttcttcgg tctcggccag
    14101 gagcagaccc acaagcacga gtcggtcttc gaagccgacc accccgccat cttcgccgcg
    14161 gaagacaacg gcatcacccc gatcgaatac ctgctcgtcg gcctggcgtc ctgcctgacc
    14221 gcgggcatcg cctcggtcgc gcagaaccgc ggcatcaagc tcaactcggt cgaggcctcc
    14281 gtcgaaggcg gccacgacat ccgcggcatc ctcggcgccg acgccgacgt ccgcaacggc
    14341 ttcaacgaca tcaaggtgac cttctcgatc gacgccgacg cctccccggc cgacatcgag
    14401 gccctcgtcg cccagtcgca gaagcgctcc gccgtcttcg acgcgctcac caaccccacg
    14461 aacgtcaccg tcgaagtcgc ctgaccatgc acgtcaccac tgtcgtcatc ggcgcgggtc
    14521 acgcgggcct ggcggccagc catttcctga gggccgcgtc gatcgaccat gtggtgctgg
    14581 aacgtggtga ggtcgccaac tcgtggcggc acgaacgctg ggactccctg cgtctcctga
    14641 cgcccaactg gctgaaccgt ctcccgggcg cctcttacga agggccggac cccgacggct
    14701 acgccgacat ggccgaggtc gtcgactttc tggagcgttc cgcgaaggac gtcccggtcc
    14761 gcaccggcgt ggcggtcacg tcggtgcggc gctcggacgg gggctactcg ctgacgacca
    14821 gccaaggccc catcgaggcc cggaccgtga tcatcgcgag cggcgcctgc aacgtcgcct
    14881 ccgttcccgg tctcgccgcc gcggtgccct cgtcggtcga gcaggtgacg ccgttcgact
    14941 accggacccc ctcccggttg ccggacggcg gcgtgctcgt cgtgggggcc tcggcgaccg
    15001 gggtgcagct cgcggccgag atccagcgct cagggcgtcc ggtcgtgctg tcggccggtg
    15061 agcacgtgcg gatgccacgt gtgtatgagg gccgtgatgt gctctggtgg atgcaccact
    15121 cgggcatctg gagccagcgc tacgacgagg tcgacgacct gacgcgcgca cgccggctgc
    15181 cgtcaccgca gctcgccggg gcctccaccc tggatctgaa cgtgctgacc tcgctgggag
    15241 tcgagctggt cgggcggctc tcggcgatcc gcgacggcgc ggcccttttc tcaggggggc
    15301 tgcgcaacgt ggcggcgctg gcggatctca agatgaaccg cctgctcgac acgttcgacg
    15361 agtgggccgg gaccgctccc ggggagcgct tccagcccac ccgcgttccc gattcgtcgc
    15421 gctggcggct cgacctcacg tcgggggaga tccgctcgat cgtgtgggcg accgggttcc
    15481 ggcccgacta ctcgtggctg gacgtgccgg tcgtcgacgc gaaggggtca ctggtccacg
    15541 acggcggcgt ggtgggcgac gggctctacg ccctcggcct gccggtgctg cgccgccgca
    15601 ggtcgacgtt catctgcggc atcgaggacg acgcccgcga ggtcgtcgac cagctacgac
    15661 tggacctggc gggttagttc tcccggacct ttcgcggcga aggcatgcga aaagcgggcc
    15721 gggaacggtc ccggcccgct tgtgtcgccg actccggtgg cgaagcgacc ttcggtcagg
    15781 ggagatcggt tcgatcacct cacgcggtgc gggccgcgtg aggcgactcc tatgccacgg
    15841 gcgggcgggt gagttcccac ttgatggtga tgacggtccg gcccgacttg ccgtgcgtgt
    15901 tgatgcgcag cgacttgccg ggaacgcagg tgtaggtgcc cttgcggggg atcgccccga
    15961 ggtcctcgtt gtgggcgacg gccttgcgga gcagaccgga gaagcccttg ccgccgccgg
    16021 agcgctccaa cgtggcgccg aagtcgccgg tgcgcggctt caggacgatc tttccgtggg
    16081 tgtacttctt gtaaccgccg aaggtgtacg tgaaggtctc gacgccgtcc atgacgaagg
    16141 tggcaccgcc cgtcaggggc tccgactcac ggaagtcgta gcgggcgacg acgtacttgc
    16201 ccgcgcgggt gaagtccgcc ttgatgccgg cgccgccctc cgcgaagaag cggtgcctct
    16261 tgccgacgac cttggcggtc gccttggtca ccgtccatga cccggcccag cacggtccct
    16321 tcgtcgcggg agccgcttgt gctgcggtgg gggcgacgag gaggcccgtg gtgagcgcga
    16381 gggctcccag taacttgtgc atcgttccgc tctcagggat cagaggtctc tcaggaagct
    16441 cccataatcg ggctaaaaga taacaattca acacttttcg agtagctgag taagtaatcg
    16501 cttgctcggc cttcacccct actcttgggc catggcgaag gagactcggc tcgggctggt
    16561 gcggcgggcc aggaagatga atcgcatcct ggccgagacc tatcccgacg cccattgcga
    16621 gctcaacttc gcgaacgcgt tccagttgct cgtggccacg gtgctgtcgg cgcagacgac
    16681 cgatgtgcgg gtcaacctga ccactccggc gctgttcgcc aaatatccga cgcctgatga
    16741 catggccgtc gccgaccccg aagacatgga ggccatcctg cggccgaccg ggttcttccg
    16801 ggccaagacg aagtcggtca tcgggctgtc catcgccatc cgcgaccggt tcggcggtga
    16861 ggttccccgc aagatggccg acctggtgac gctgcccggg gtcggccgca agacggccaa
    16921 cgtcgtgctc ggcaacgcgt tcggcgtgcc ggggctgacc gtcgacaccc acttccagcg
    16981 gctggtgaag cggttcgggt ggatcgaggg ggagctcgac ccggtcaaga tcgagcagga
    17041 gatcgcactg ctcatcccga agaacgagtg gacggtcttc tcccaccgca tcatctggca
    17101 cggccgccgg atctgcatcg cccgcaaacc cgcctgcggc gcgtgccctc tcgcggacct
    17161 ctgtccttct tacggcaccg gtccgaccga cccggaactg gcgtccaagc tggtacgttc
    17221 cggaccgttc tcgtgacggg aagcttcgcg gggcaccgag ggttggactg tccatgaccg
    17281 acgtaccggc ctggatcacc gatgtggcgg agagggccgg gcgaacccct gttcctcccg
    17341 gcctgcgccc gcctcgcgaa ggtggccggc gggccgccgt gctgctgctg ttcggcgacg
    17401 ggccgaacgg gcccgacatc ctgctcatcc agcgcagttc ccgcggacgc acccacgccg
    17461 gccagcccgc cttccccggc ggcggggtcg acccggatga cgacggtccc gtcggggccg
    17521 ccctgcgtga ggcggccgag gagacgggcg tcgaccccga gggtgtcgcg gtcgtcggca
    17581 ccatgcccga gctctacgtc cggcacagcg acaaccgcgt cacccccgtc atcggctggt
    17641 ggcacacccc ctgtgccgtc cacgccgcct cacccgacga ggtcgagtcg gtcgaacgcg
    17701 tctccatcgc cgagctggtc gaccccgcca accggctcag gctgcgtcat tccagcggat
    17761 acatcggccc cgcgttccgg gtgcgcggcc tgctggtctg gggcttcacc gccggagtgc
    17821 tcgacggcgt gctctcgacc tgcggtttcg aggtcccgtg ggaccggtca cggatcgagg
    17881 acctgccccc tgacgtcgtg aacctcgccg cccgttagcg ccagccccag cgtcgcccag
    17941 tcggccacgt cgtcgtcgcg gtcggccgcc aggcgccgca gtgcggcgac ccccgacggg
    18001 tcggccggtc ggccgatgac gttgggcagg gcgtaggcgg cgccgtaccg aaccgtcgtc
    18061 tccggatgag acgcgagctc gatcaccgac ggcagcgccc tcgggtcgcg caggtggccg
    18121 aaagcgatga gcaccgagta gagcacgcgg gtctcggtct cgctcgcggc caggaatctc
    18181 agcaccggca gggtcttgtc ggcgaacggg cggtcgcgcc cgagctcccc caggatgtcg
    18241 actccgagaa ctctctcggc tgccgtgtcg gctgcgcaca gtcgtcgtgc ggcggtgaag
    18301 gtctccaggt caccgcgttg ctgcagggcc gcgatggcgt cccagcgggt cgggccgtcc
    18361 gggtctccgt cggccagtgc tgtctggatc agttcctcaa cagggtcccc catggcgtca
    18421 cgatatcgag tggactgcga agaacccgtg cacgagaccg cgcgtggctg gatacggtta
    18481 agggtggtgg ccgggccggg tggcgataga ggtggaatac aggcgtgcaa ggcgatctgc
    18541 tcgacctcat cctgatcggc ctgatcctgg ccttcgcggt gtccggctat cgccaggggt
    18601 tcatcatcgg ggcgttcagc ttcgtcggct tcgccggtgg ggcgctcgtc gggatgttca
    18661 tcgcgccgcc catcgccgga gccctcgtca acggtgagac cgaacgcgcc ctgctcgcca
    18721 tagtcatcgt gttcctcgcc gcgacggtcg gccagttcgc ctcctcgacg atcggcgcgg
    18781 tcgtccgatc ccacgtgacg tgggaacccg cccgtctcat cgacgccttc ggcggctccg
    18841 tggcgagtgg gctctccgtg ctggtgttcg cctggctcat cgggtcgctc atcatctcga
    18901 tgaacttccc gctgccgaaa cagcaggtca acgactcgct gctgctgaag acggtcgacc
    18961 aggcgatgcc cgaggcggcg cgtgacctga cgcgcgggtt ccgcgacttc gtcgacgcct
    19021 ctccgtggcc cgaggtcttc gccgacatcg gcggcgcgca gttcgtcgac gtgcccgccc
    19081 ccgacgagag catcatcaac gacccgcagc tggcccgcgc gcgccgcgcg atcgtgaagg
    19141 tgcagggcac cgccccgacg tgccgcaaac gcatcgaggg caccggtttc gcctacgccc
    19201 cccaccgcat catgaccaac gcccacgtgg tggccggggt gtcgcaggac ctgcgcgtca
    19261 ccgactaccg gggcgccagc cacgacgccc gggtcgtgct ctacaacccc gaccgggaca
    19321 tcgcggtcct ctacgtcgag tcgctcgacg tcaacccgct gaagttcgac atggcggccg
    19381 agtcgaaaga cgacgccatc atcgcgggct acccgaaggg ccacggcttc accatcaagc
    19441 cggcccgcat ccgggtgaag cagcccgccg agtcctacga catctacaac cgccacaccg
    19501 tcgaccgcga ggtctacgcg atccgcggcg aggtgcagcc cggcaactcc ggcggcccgc
    19561 tccttgcccc cgacgggcgc gtcttcggcg tcatcttcgc ggcggccacc gaccagaagg
    19621 acaccggcta cgcgctgacg gccgaagagg tccgcaccga cgcggaagac ggcagcgcgg
    19681 ccatcgcgcg ggtcgacacg caggaatgtg actgaccctc actccgccga cgtcaccacc
    19741 gcgtctcccg tccggctgcg gtagtagagc accgatttgc cggctcttct gcgttcgacc
    19801 agccccgcgt ccaggagcac cttcaggtgg cggccgaccg aaccgagccc ctggcccgtc
    19861 agcgcgacga gctgggtcgt gctcttgggc gtgtccagca ggacgagcac cgtcgcccgc
    19921 gcgctgccca gcaggcgccc gaggggcccc gatacttcgc ggacgtcggt cagcaccccc
    19981 gacgctggat atatcaccgc atagcgatgc ggctgctccc atgacaccca cccgtgccgg
    20041 ggcgtgaccg ggacgaacat caggcgcgcc gtcgccaggt ccctgggcgg gttgctggtc
    20101 gtgttgatct gcaaccggct ctcgccgagc cagcgcatcc ccggacgcat gtcgttgagg
    20161 gccgcctccc agccgcccat gctgaggcgg ccgatacggc cgatgatgtc ggcttcgagg
    20221 atgcgtctgc gccggtccca ggtgggttcg accgtttccg tccacaccca ttccagcagg
    20281 gaggccgccc gttcggccag gtcggaccgg cggagcgggc ccggcagcat cctgcccagg
    20341 gagacctcga gatcggcgta caccacgcct gcgggggtgt cccggacggt ggcgacctcc
    20401 tcggcgaacg tcggttcgcc ggtgccggcc ggggtcggga cgaggaagtc ggcgatccac
    20461 tcggctccgg tcgcggcgcg gatcaggaat tcgtcgaggg ggtcgcgggt gaggcgggtc
    20521 ttgaagcggt cggcgtgctg gtcccaccag ggcttctcac ctggatgggc ggggagggtg
    20581 cggccgagcg cgaacatgca cgcggtggtc tcggcgagcg gcgacagcac gaacctgctc
    20641 ccggccaacg tatcggcgtt gacctgccac cagcccatct atccgcctcc cgtgtcgatc
    20701 ttccggtgtt gctcgtgcgc cggggccgtt gattcgtgtc gcaggccaca cagcgggggc
    20761 ctgtcatcag cccacatgtc ggctctcacc gtgacattcc gggttttgcc acatatcggg
    20821 ccaaccctcc ggctcccgtg aagtcatgtc cgcggcagcc ctttcgccgt gggtcgtttc
    20881 gcatactggc gaaacaatac cggctctgac ctgggatgat ggaatgtcgg ccc
//
