LOCUS       NZ_KQ948891             9739 bp    DNA     linear   CON 21-APR-2024
DEFINITION  Streptomyces bungoensis strain DSM 41781 PRJNA299233_s041, whole
            genome shotgun sequence.
ACCESSION   NZ_KQ948891
VERSION     NZ_KQ948891.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces bungoensis
  ORGANISM  Streptomyces bungoensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9739)
  AUTHORS   Ruckert,C., Winkler,A., Kalinowski,J., Kampfer,P. and Glaeser,S.
  TITLE     Draft genome sequence of Streptomyces bungoensis DSM 41781, type
            strain for the species Streptomyces bungoensis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9739)
  AUTHORS   Ruckert,C., Winkler,A., Kalinowski,J., Kampfer,P. and Glaeser,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-OCT-2015) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 13-OCT-2014
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 60.6x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001514215.1-RS_2024_04_21
            Annotation Date                   :: 04/21/2024 02:15:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,539
            CDSs (total)                      :: 7,454
            Genes (coding)                    :: 7,226
            CDSs (with protein)               :: 7,226
            Genes (RNA)                       :: 85
            rRNAs                             :: 1, 1 (5S, 16S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            tRNAs                             :: 80
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 237
            CDSs (without protein)            :: 228
            Pseudo Genes (ambiguous residues) :: 0 of 237
            Pseudo Genes (frameshifted)       :: 67 of 237
            Pseudo Genes (incomplete)         :: 196 of 237
            Pseudo Genes (internal stop)      :: 10 of 237
            Pseudo Genes (multiple problems)  :: 43 of 237
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:26:42
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 9739
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KQ948891.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     gene            complement(<1..>9714)
                     /locus_tag="AQJ66_RS36430"
                     /old_locus_tag="AQJ66_36425"
                     /pseudo=""
     CDS             complement(<1..9714)
                     /NRPS_PKS="Domain: ACP (21-94). E-value: 1.8e-32. Score:
                     103.4. Matches aSDomain:
                     nrpspksdomains_AQJ66_RS36430_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (120-545). E-value:
                     2.1e-176. Score: 578.9. Matches aSDomain:
                     nrpspksdomains_AQJ66_RS36430_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (657-951). E-value: 8e-115.
                     Score: 375.2. Matches aSDomain:
                     nrpspksdomains_AQJ66_RS36430_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (1020-1189). E-value: 6e-61.
                     Score: 197.6. Matches aSDomain:
                     nrpspksdomains_AQJ66_RS36430_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_PP (1387-1473). E-value: 4.4e-29.
                     Score: 92.7. Matches aSDomain:
                     nrpspksdomains_AQJ66_RS36430_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (1494-1920). E-value:
                     9.2e-179. Score: 586.7. Matches aSDomain:
                     nrpspksdomains_AQJ66_RS36430_PKS_KS.2"
                     /NRPS_PKS="Domain: PKS_AT (2040-2338). E-value: 6e-111.
                     Score: 362.5. Matches aSDomain:
                     nrpspksdomains_AQJ66_RS36430_PKS_AT.2"
                     /NRPS_PKS="Domain: PKS_KR (2687-2867). E-value: 9.3e-56.
                     Score: 180.6. Matches aSDomain:
                     nrpspksdomains_AQJ66_RS36430_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2971-3056). E-value: 1.8e-29.
                     Score: 93.9. Matches aSDomain:
                     nrpspksdomains_AQJ66_RS36430_PKS_PP.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491080.1"
                     /locus_tag="AQJ66_RS36430"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="AQJ66_36425"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /pseudo=""
                     /sec_met_domain="PP-binding (E-value: 5.8e-18, bitscore:
                     51.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.3e-116, bitscore:
                     375.2, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 8.7e-230, bitscore:
                     748.9, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.2e-96, bitscore:
                     308.4, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 8.6e-63, bitscore:
                     197.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTALRERLADLSRAERDRRLLELVRTGAAAVLGHADAGAVEATR
                     SFRDLGFDSLTAVELRNRLSAETGLKLPSTLVFDHPTPAALVRLLRRELLGEDDDGRGT
                     DTRQPVPAVTSTTDDPVVVVGMACRLPGGVSGPDDLWRLVSEGADAISEFPADRGWDLD
                     ALHGSPDGAGQGRSHTRAGGFLADAAQFDPGFFGISPREALAVDPQQRLLLEASWEALE
                     HAAIRPDSLRGSRTGVFVGAGGSGYGAGLREVPEGLDGQLLTGVAGSVVSGRVAYTFGF
                     EGPAVTVDTACSSSLVALHLAAQSLRSAECDLALVGGVTVLADPAAFVEFSAQGGLAAD
                     GRCKAFSDDADGTGWAEGVGVLVVERLSDARRNGHDVLAVIAGSAVNQDGASNGLTAPN
                     GPAQQRVIRQALAGAGLTPADVDAVEAHGTGTTLGDPIEAQALLATYGQDRERPLYLGS
                     LKSNIGHTQAAAGVAGVIKTVLAMRHGVLPRTLHAERPSSHVDWSAGDIALLTENVEWP
                     RTEGRPRRAGVSAFGVSGTNAHVVLEQPAPEPVPEDDPAGVPDAAAPEPPLLPWVVSGR
                     TRAALCAQAERLAAFAEARPGTAPAEIAASLVRSRSVFEHRAVVWGAGRDELLGGLRAL
                     ASGQRSDATVTGSVLADGRTACLFAGQGSQRPGMGRELYERYPVFADAFDAVCAHMDTE
                     LPRPLREVVFGDDAGPLNRTEFAQPALFALEVALFRLLESWGVRPDVLLGHSIGELTAA
                     HAAGVWSLADACRLVAARGRLMQALPEGGAMVSLQASEEEVLPLLAGRETEAGVAAVNG
                     PLSLVVSGTEDAVREIAAAVEALGRRTRRLRVSHAFHSPLMEPMLADFRAVAETLSYAA
                     PRIPVVSDVTGRPATAEELTSPEYWVRHVRQAVRFADGVSALAGQNVTRWLELGPDSTL
                     TTLAQSCPGAADGLYVPALRDDRPEARALLEAVSALFTRGADIDWTAPVPALGRARRTA
                     LPTYAFQRRRYWLDVPAGPHDASALGLDDTGHPLLTAALPAADSDAVVLTGRLSLRSHP
                     WLADHRIGGHAVVPSTAFLELAVHAGDQVGCDEVRELTLEAPLTVPERGAVRLQVRIGE
                     PDARGTRAVTVHSRPDGAPSDGTAWTRHAGGLLAPAGTTAGRPETGLAAWPPPGAEQVE
                     IGDLYERLAAGPGLEYGPAFRALTAVWRHGENVYAEVALGADERERARRFGVHPALLDA
                     ALHPLGLGLPAGVGDGLVLFAWQRATLLAHGAGTLRIRLTRSGGDTLTLLAADASGLPV
                     LTVDSLRLRPAPAGQARTACDPADTDPADTGQAVTGQMAPDERTDPAAADARADTAAGP
                     RTQEDPAGSGPLPSTDPRRTKRRRAADDSGAGDGPGDGTGLLERLAGRSAAERRRALLD
                     LVRRTVAAVLDYVDLDEVEPGRVFKDLGFASVTAVELRNRLSAGLGVLLPATLVFDHPT
                     PLALAAHLDAELFGAATGTTAPVASRARLDDDPVVVVGMACRYPGGITSPEELWDLVAD
                     RGDGISPFPTDRGWDLAKLYHPDPDHPGTCYAREGGFLHHASHFDPGFFGISPREALAM
                     DPQQRLLLETSWEALERAGIDPASQRGSLTGVFAGVTYQDYVGILGAAEDSFEGYIGTG
                     NSPSVLSGRIAYALGLEGPALSVDTACSSSLVALHLGVQSLRQGECDLALAGGVTVMST
                     PGSLIEFSRQRALAEDGRCKPFSADADGASWAEGAGMIVLERFSDARRHGHPVLAVVQG
                     SALNQDGASNGLTAPNGPSQQRVIRAALAAGGLAPTDVDAVEAHGTGTTLGDPIEAQAL
                     IAVYGQDRPADRPLWLGSLKSNIGHAQAAAGVGGVIKMVMALRHGLLPATLHAGTPTPE
                     VDWSAGTVRLLDDAVPWPETGRPRRAGVSSFGMSGTNAHVVIQQAPDEPAHQDTTTGGA
                     QRTGPAAPDTAPARVLPLVPAPLSARTSDGLRAQAGRLLAHLRDHPGLGLADLGLSLAT
                     TRTAFEHRAVVLAADRDALERGLRDLAGDGMVSDVVRGVDRRGAGPVLVFPGQGAQWAG
                     MGRELLDTAPEFAHRIAECEQALAPHVDWSLTAALRGGPDAPDLDRVDVVQPVLWAVMV
                     SLAHLWRTHGVEPAAVVGHSQGEIAAAVVAGVLSLEDGARVAALRSKAITAIAGDGGMM
                     SVPLPADQVRGRLERHGDRLALAAVNGPGSVVVSGAADALDELYTELTAEGVQARKVAV
                     DYGSHSAHVEPIRDQVLDALADLRPGPAEIPFRSSVTGDWLDDDTVLDAAYWYTSLRET
                     VRFEDAVRGLLTAGHRAFIEVSPHPVVGFGLRETIEDAAADAVVLGTLRRDHGGLDRFL
                     TSLAEAHAHGVPVDWRCVFAGTGAHRVDLPTYAFQRMRYWPELRAADTAAETATEVSDE
                     VDSRFWRTVDEEDLEGLAATLDLAGDAPLREVLPALSAWRRSSREQSTVDGWRYTVGWS
                     PLTQDTAGAPPAGTWLLVVPGTGHPLADATRQALTGHGVPVRVVPVATGGHDADRTVLA
                     TLLTGALAGTGTEPAVAPQDLGGVLSLLALDESPHPDHPSVPAGLAGTLALLQALGDLG
                     VAAPLWCATRGAVAVTGSEAVLSAPQALVWGLGRVAALEHSDRWGGLIDLPADLDRRAG
                     DRLCALLARPDGEDQTALRASGGYGRRLLRAPLAGATAPAEPWRPRGTVLVTGGTGAVG
                     GHVSRWLASLGADHLLLTSRRGAEAPGAAELRAELTALGAGRVTIAACDVTDRDALREL
                     LDTIPEEHPLDAVLHIAGSLDDGVIDALDPGRMDPVLRTKATAAVHLHELTRDLDLSAF
                     VLFSSTSGTISGPGLGNYAPGNAFLDALAQQRRAQGLPATAVAWGHWADGGMGDGAVGE
                     RLRRYGVYDMQPELACQALQQALDHGETHLAVTDIGWDRFAPAFTGSRASALLRDLPDA
                     RRVLAPAAGNASGQNAGSAFGGDSTDGDQPPLRRHLAGLTGTERADAVLDVVRGYVATV
                     LGHPGPQAVDPSRAFSDLGFDSLSAVELRNGMNKITGLRLPATLVFDHPNCAELARMLL
                     HELGDAPGDDDRPPTTRAEAAAPVAPCVTEGDPVVITAMSCRFPGGVSTPEEFWRLLAD
                     GTDAIAPFPADRGWDVEGLYHPDPDHPGTCTAREGGFLRDMAAFDPAFFGVSPREALAM
                     DPQQRLLLELAWEAFERAGIDPTTLRGSRTGVFAGTNGNDYTPLLVASGEDVGGHLGTG
                     NAASVVS"
     source          1..9739
                     /country="Japan"
                     /culture_collection="DSM:41781"
                     /db_xref="taxon:285568"
                     /isolation_source="soil"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces bungoensis"
                     /strain="DSM 41781"
                     /submitter_seqid="PRJNA299233_s041"
                     /type_material="type strain of Streptomyces bungoensis"
     region          1..9739
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..9739
                     /SMILES="CC(=O)C(C)C(O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..9739
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[<0:9714](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..9714)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     CDS_motif       complement(172..198)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0026"
                     /evalue="5.90E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="3181"
                     /protein_start="3172"
                     /score="6.7"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     aSDomain        complement(547..801)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AQJ66_RS36430_PKS_PP.2"
                     /evalue="1.80E-29"
                     /label="AQJ66_RS36430_PKS_PP.2"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="3056"
                     /protein_start="2971"
                     /score="93.9"
                     /tool="antismash"
                     /translation="LAGLTGTERADAVLDVVRGYVATVLGHPGPQAVDPSRAFSDLGFD
                     SLSAVELRNGMNKITGLRLPATLVFDHPNCAELARMLLHE"
     aSModule        complement(547..5232)
                     /complete
                     /domains="nrpspksdomains_AQJ66_RS36430_PKS_KS.2"
                     /domains="nrpspksdomains_AQJ66_RS36430_PKS_AT.2"
                     /domains="nrpspksdomains_AQJ66_RS36430_PKS_KR.1"
                     /domains="nrpspksdomains_AQJ66_RS36430_PKS_PP.2"
                     /locus_tags="AQJ66_RS36430"
                     /monomer_pairings="mmal -> Me-ohmal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(1114..1653)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AQJ66_RS36430_PKS_KR.1"
                     /evalue="9.30E-56"
                     /label="AQJ66_RS36430_PKS_KR.1"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="2867"
                     /protein_start="2687"
                     /score="180.6"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B2"
                     /tool="antismash"
                     /translation="GTVLVTGGTGAVGGHVSRWLASLGADHLLLTSRRGAEAPGAAELR
                     AELTALGAGRVTIAACDVTDRDALRELLDTIPEEHPLDAVLHIAGSLDDGVIDALDPGR
                     MDPVLRTKATAAVHLHELTRDLDLSAFVLFSSTSGTISGPGLGNYAPGNAFLDALAQQR
                     RAQGLPATAVAWGHWAD"
     CDS_motif       complement(1162..1266)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0025"
                     /evalue="2.50E-16"
                     /label="PKSI-KR_m4"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="2851"
                     /protein_start="2816"
                     /score="52.2"
                     /tool="antismash"
                     /translation="AFVLFSSTSGTISGPGLGNYAPGNAFLDALAQQRR"
     CDS_motif       complement(1552..1650)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0024"
                     /evalue="1.20E-10"
                     /label="PKSI-KR_m1"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="2721"
                     /protein_start="2688"
                     /score="34.0"
                     /tool="antismash"
                     /translation="TVLVTGGTGAVGGHVSRWLASLGADHLLLTSRR"
     CDS_motif       complement(1933..1983)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0023"
                     /evalue="7.50E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="2594"
                     /protein_start="2577"
                     /score="-0.6"
                     /tool="antismash"
                     /translation="LGDLGVAAPLWCATRGA"
     aSDomain        complement(2701..3594)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AQJ66_RS36430_PKS_AT.2"
                     /evalue="6.00E-111"
                     /label="AQJ66_RS36430_PKS_AT.2"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="2338"
                     /protein_start="2040"
                     /score="362.5"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGAQWAGMGRELLDTAPEFAHRIAECEQALAPHVDWSLTAA
                     LRGGPDAPDLDRVDVVQPVLWAVMVSLAHLWRTHGVEPAAVVGHSQGEIAAAVVAGVLS
                     LEDGARVAALRSKAITAIAGDGGMMSVPLPADQVRGRLERHGDRLALAAVNGPGSVVVS
                     GAADALDELYTELTAEGVQARKVAVDYGSHSAHVEPIRDQVLDALADLRPGPAEIPFRS
                     SVTGDWLDDDTVLDAAYWYTSLRETVRFEDAVRGLLTAGHRAFIEVSPHPVVGFGLRET
                     IEDAAADAVVLGTLRRD"
     CDS_motif       complement(2845..2892)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0022"
                     /evalue="4.70E-04"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="2290"
                     /protein_start="2274"
                     /score="12.7"
                     /tool="antismash"
                     /translation="LDAAYWYTSLRETVRF"
     CDS_motif       complement(3001..3033)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0021"
                     /evalue="1.70E-02"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="2238"
                     /protein_start="2227"
                     /score="8.3"
                     /tool="antismash"
                     /translation="VDYGSHSAHVE"
     CDS_motif       complement(3103..3141)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0020"
                     /evalue="4.30E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="2204"
                     /protein_start="2191"
                     /score="10.5"
                     /tool="antismash"
                     /translation="AAVNGPGSVVVSG"
     CDS_motif       complement(3247..3357)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0019"
                     /evalue="1.20E-17"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="2156"
                     /protein_start="2119"
                     /score="55.8"
                     /tool="antismash"
                     /translation="GVEPAAVVGHSQGEIAAAVVAGVLSLEDGARVAALRS"
     CDS_motif       complement(3364..3432)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0018"
                     /evalue="5.30E-10"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="2117"
                     /protein_start="2094"
                     /score="31.4"
                     /tool="antismash"
                     /translation="LDRVDVVQPVLWAVMVSLAHLWR"
     CDS_motif       complement(3544..3600)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0017"
                     /evalue="5.50E-09"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="2057"
                     /protein_start="2038"
                     /score="27.7"
                     /tool="antismash"
                     /translation="VLVFPGQGAQWAGMGRELL"
     aSDomain        complement(3955..5232)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AQJ66_RS36430_PKS_KS.2"
                     /domain_subtypes="Modular-KS"
                     /evalue="9.20E-179"
                     /label="AQJ66_RS36430_PKS_KS.2"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="1920"
                     /protein_start="1494"
                     /score="586.7"
                     /tool="antismash"
                     /translation="VVVVGMACRYPGGITSPEELWDLVADRGDGISPFPTDRGWDLAKL
                     YHPDPDHPGTCYAREGGFLHHASHFDPGFFGISPREALAMDPQQRLLLETSWEALERAG
                     IDPASQRGSLTGVFAGVTYQDYVGILGAAEDSFEGYIGTGNSPSVLSGRIAYALGLEGP
                     ALSVDTACSSSLVALHLGVQSLRQGECDLALAGGVTVMSTPGSLIEFSRQRALAEDGRC
                     KPFSADADGASWAEGAGMIVLERFSDARRHGHPVLAVVQGSALNQDGASNGLTAPNGPS
                     QQRVIRAALAAGGLAPTDVDAVEAHGTGTTLGDPIEAQALIAVYGQDRPADRPLWLGSL
                     KSNIGHAQAAAGVGGVIKMVMALRHGLLPATLHAGTPTPEVDWSAGTVRLLDDAVPWPE
                     TGRPRRAGVSSFGMSGTNAHVVIQQAP"
     CDS_motif       complement(4177..4221)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0016"
                     /evalue="7.90E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="1846"
                     /protein_start="1831"
                     /score="9.2"
                     /tool="antismash"
                     /translation="GSLKSNIGHAQAAAG"
     CDS_motif       complement(4282..4326)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0015"
                     /evalue="1.00E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="1811"
                     /protein_start="1796"
                     /score="11.5"
                     /tool="antismash"
                     /translation="VEAHGTGTTLGDPIE"
     CDS_motif       complement(4522..4560)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0014"
                     /evalue="3.20E+00"
                     /label="PKSI-KS_m4"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="1731"
                     /protein_start="1718"
                     /score="2.0"
                     /tool="antismash"
                     /translation="FSADADGASWAEG"
     CDS_motif       complement(4702..4749)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0013"
                     /evalue="4.20E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="1671"
                     /protein_start="1655"
                     /score="18.8"
                     /tool="antismash"
                     /translation="GPALSVDTACSSSLVA"
     CDS_motif       complement(4951..4977)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0012"
                     /evalue="5.90E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="1588"
                     /protein_start="1579"
                     /score="6.7"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     aSDomain        complement(5296..5553)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AQJ66_RS36430_PKS_PP.1"
                     /evalue="4.40E-29"
                     /label="AQJ66_RS36430_PKS_PP.1"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="1473"
                     /protein_start="1387"
                     /score="92.7"
                     /tool="antismash"
                     /translation="LAGRSAAERRRALLDLVRRTVAAVLDYVDLDEVEPGRVFKDLGFA
                     SVTAVELRNRLSAGLGVLLPATLVFDHPTPLALAAHLDAEL"
     aSModule        complement(5296..9354)
                     /complete
                     /domains="nrpspksdomains_AQJ66_RS36430_PKS_KS.1"
                     /domains="nrpspksdomains_AQJ66_RS36430_PKS_AT.1"
                     /domains="nrpspksdomains_AQJ66_RS36430_PKS_DH.1"
                     /domains="nrpspksdomains_AQJ66_RS36430_PKS_PP.1"
                     /locus_tags="AQJ66_RS36430"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(6148..6654)
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AQJ66_RS36430_PKS_DH.1"
                     /evalue="6.00E-61"
                     /label="AQJ66_RS36430_PKS_DH.1"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="1189"
                     /protein_start="1020"
                     /score="197.6"
                     /tool="antismash"
                     /translation="HPLLTAALPAADSDAVVLTGRLSLRSHPWLADHRIGGHAVVPSTA
                     FLELAVHAGDQVGCDEVRELTLEAPLTVPERGAVRLQVRIGEPDARGTRAVTVHSRPDG
                     APSDGTAWTRHAGGLLAPAGTTAGRPETGLAAWPPPGAEQVEIGDLYERLAAGPGLEYG
                     PAFRAL"
     CDS_motif       complement(6496..6570)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0011"
                     /evalue="2.20E-09"
                     /label="PKSI-DH_m2"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="1073"
                     /protein_start="1048"
                     /score="29.8"
                     /tool="antismash"
                     /translation="WLADHRIGGHAVVPSTAFLELAVHA"
     aSDomain        complement(6862..7743)
                     /ASF="Malonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AQJ66_RS36430_PKS_AT.1"
                     /evalue="8.00E-115"
                     /label="AQJ66_RS36430_PKS_AT.1"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="951"
                     /protein_start="657"
                     /score="375.2"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFAGQGSQRPGMGRELYERYPVFADAFDAVCAHMDTELPRPLREV
                     VFGDDAGPLNRTEFAQPALFALEVALFRLLESWGVRPDVLLGHSIGELTAAHAAGVWSL
                     ADACRLVAARGRLMQALPEGGAMVSLQASEEEVLPLLAGRETEAGVAAVNGPLSLVVSG
                     TEDAVREIAAAVEALGRRTRRLRVSHAFHSPLMEPMLADFRAVAETLSYAAPRIPVVSD
                     VTGRPATAEELTSPEYWVRHVRQAVRFADGVSALAGQNVTRWLELGPDSTLTTLAQSCP
                     GAADGLYVPALRD"
     CDS_motif       complement(6997..7032)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0010"
                     /evalue="2.20E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="906"
                     /protein_start="894"
                     /score="14.6"
                     /tool="antismash"
                     /translation="YWVRHVRQAVRF"
     CDS_motif       complement(7255..7293)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0009"
                     /evalue="4.20E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="820"
                     /protein_start="807"
                     /score="10.5"
                     /tool="antismash"
                     /translation="AAVNGPLSLVVSG"
     CDS_motif       complement(7387..7509)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0008"
                     /evalue="8.00E-24"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="776"
                     /protein_start="735"
                     /score="76.0"
                     /tool="antismash"
                     /translation="GVRPDVLLGHSIGELTAAHAAGVWSLADACRLVAARGRLMQ"
     CDS_motif       complement(7519..7581)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0007"
                     /evalue="1.50E-03"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="732"
                     /protein_start="711"
                     /score="11.9"
                     /tool="antismash"
                     /translation="NRTEFAQPALFALEVALFRLL"
     CDS_motif       complement(7693..7740)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0006"
                     /evalue="1.80E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="674"
                     /protein_start="658"
                     /score="17.3"
                     /tool="antismash"
                     /translation="FAGQGSQRPGMGRELY"
     aSDomain        complement(8080..9354)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AQJ66_RS36430_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="2.10E-176"
                     /label="AQJ66_RS36430_PKS_KS.1"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="545"
                     /protein_start="120"
                     /score="578.9"
                     /tool="antismash"
                     /translation="VVVVGMACRLPGGVSGPDDLWRLVSEGADAISEFPADRGWDLDAL
                     HGSPDGAGQGRSHTRAGGFLADAAQFDPGFFGISPREALAVDPQQRLLLEASWEALEHA
                     AIRPDSLRGSRTGVFVGAGGSGYGAGLREVPEGLDGQLLTGVAGSVVSGRVAYTFGFEG
                     PAVTVDTACSSSLVALHLAAQSLRSAECDLALVGGVTVLADPAAFVEFSAQGGLAADGR
                     CKAFSDDADGTGWAEGVGVLVVERLSDARRNGHDVLAVIAGSAVNQDGASNGLTAPNGP
                     AQQRVIRQALAGAGLTPADVDAVEAHGTGTTLGDPIEAQALLATYGQDRERPLYLGSLK
                     SNIGHTQAAAGVAGVIKTVLAMRHGVLPRTLHAERPSSHVDWSAGDIALLTENVEWPRT
                     EGRPRRAGVSAFGVSGTNAHVVLEQP"
     CDS_motif       complement(8302..8346)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0005"
                     /evalue="4.50E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="471"
                     /protein_start="456"
                     /score="9.8"
                     /tool="antismash"
                     /translation="GSLKSNIGHTQAAAG"
     CDS_motif       complement(8401..8445)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0004"
                     /evalue="1.00E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="438"
                     /protein_start="423"
                     /score="11.5"
                     /tool="antismash"
                     /translation="VEAHGTGTTLGDPIE"
     CDS_motif       complement(8641..8679)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0003"
                     /evalue="2.70E-01"
                     /label="PKSI-KS_m4"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="358"
                     /protein_start="345"
                     /score="5.2"
                     /tool="antismash"
                     /translation="FSDDADGTGWAEG"
     CDS_motif       complement(8821..8868)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0002"
                     /evalue="1.70E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="298"
                     /protein_start="282"
                     /score="19.9"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       complement(9070..9096)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS36430_0001"
                     /evalue="5.90E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="215"
                     /protein_start="206"
                     /score="6.7"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     aSDomain        complement(9433..9651)
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AQJ66_RS36430_ACP.1"
                     /evalue="1.80E-32"
                     /label="AQJ66_RS36430_ACP.1"
                     /locus_tag="AQJ66_RS36430"
                     /protein_end="94"
                     /protein_start="21"
                     /score="103.4"
                     /tool="antismash"
                     /translation="LELVRTGAAAVLGHADAGAVEATRSFRDLGFDSLTAVELRNRLSA
                     ETGLKLPSTLVFDHPTPAALVRLLRREL"
ORIGIN
        1 ggagacgacg ctcgccgcgt tgccggtgcc caggtggcct ccgacgtcct cgccggaggc
       61 gacgaggagc ggggtgtagt cgttgccgtt ggtgccggcg aacactccgg tgcgggagcc
      121 gcgcagcgtc gtcgggtcga tcccggcccg ttcgaacgcc tcccacgcca gctccagcag
      181 cagccgctgc tgcgggtcca tcgccagcgc ctcacgcggg gagacgccga agaaggcggg
      241 gtcgaaggcg gccatgtccc gcaggaaccc gccttcgcgg gcggtgcagg tgccggggtg
      301 gtcggggtcg gggtggtaca ggccctcgac gtcccagcca cggtcggccg ggaagggggc
      361 gatggcgtcg gtgccgtcgg ccagcagccg ccagaactcc tccggggtgc tcaccccgcc
      421 cgggaaacgg cagctcatcg cggtgatgac gaccgggtcg ccctcggtga cgcacggtgc
      481 gaccggtgcg gcggcctcgg cccgggtggt gggcggccgg tcgtcgtcac cgggggcgtc
      541 gccgagttcg tgcagcagca tccgcgcgag ttcggcgcag ttggggtggt cgaagaccag
      601 ggtggcaggc agccgcagtc cggtgatctt gttcatgccg ttgcggagtt cgacggcgct
      661 cagcgagtcg aagcccaggt cgctgaaggc acggctcggg tcgacggcct gcggtccggg
      721 gtggccgagg acggtggcga catagccgcg cacgacgtcg aggacggcgt cggcgcgttc
      781 ggttccggtg aggcccgcca gatggcggcg cagcggtggc tggtccccgt cggtggagtc
      841 gccgccgaag gcgctcccgg cgttctggcc ggaggcgttg ccggccgccg gggcgaggac
      901 gcgccgggcg tcgggcaggt cgcgcagcag ggcgctggcg cgggagccgg tgaaggcggg
      961 ggcgaagcgg tcccagccga tgtcggtgac cgcgaggtgg gtctcgccgt ggtcgagtgc
     1021 ctgctgcagg gcctggcagg cgagttcggg ctgcatgtcg tagacgccgt agcggcgcag
     1081 gcgttcgccg accgcgccgt cgcccatgcc gccgtcggcc cagtggcccc aggcgacggc
     1141 ggtggcgggc aggccctggg cgcggcgctg ctgggcgagg gcgtccagga aggcgttgcc
     1201 gggggcgtag ttgccgaggc cggggccgct gatggtgcct gaggtcgagg agaacaggac
     1261 gaacgcggac aggtccaggt cccgggtcag ttcgtgcagg tggacggcgg ccgtggcctt
     1321 ggtgcgcagc accgggtcca tgcggccggg gtcgagggcg tcgatgacgc cgtcgtcgag
     1381 ggagccggcg atgtgcagga ccgcgtcgag cgggtgctcc tcggggatcg tgtcgaggag
     1441 ttcccgcagc gcgtcccggt cggtgacgtc gcaggcggcg atggtgacgc ggcccgcgcc
     1501 cagcgcggtg agttcggccc gcagttcggc cgcgccgggt gcttcggcgc cgcggcggct
     1561 ggtgagcagc aggtggtcgg cgccgaggga ggcgagccag cgggagacgt ggccgccgac
     1621 cgcgccggtg ccgccggtga ccaggacggt gccgcgcggg cgccagggct cggccggtgc
     1681 ggtggcgccg gcgagcgggg cgcgcagcag gcggcggccg tagccgcccg atgcgcgcag
     1741 ggcggtctgg tcctcgccgt cgggccgggc gagcagggcg cacagccggt cgccggcccg
     1801 gcggtccagg tccgcgggca ggtcgatcag gcctccccag cggtcggagt gttccagggc
     1861 ggcgacccgg ccgagacccc acacgagggc ctggggcgcg ctgaggacgg cttccgatcc
     1921 ggtgacggcg accgcgccgc gggtggcgca ccacaggggt gccgcgacgc cgaggtcgcc
     1981 cagggcctgg aggagggcca gcgtgccggc gagtccggcg ggtacggacg ggtggtcggg
     2041 gtgggggctc tcgtccagtg cgaggagcga cagcacgccg ccgaggtcct gcggggcgac
     2101 cgcgggctcg gtgccggtgc cggcgagcgc cccggtcagc agggtggcca ggacggtgcg
     2161 gtcggcgtcg tggccgcccg tggcgacggg gacgacgcgg acgggcacgc cgtggccggt
     2221 gagggcctgc cgggtggcgt cggccagcgg gtggccggtg ccgggcacga cgaggagcca
     2281 ggtgccggcc gggggcgcgc ccgcggtgtc ctgggtgagc gggctccagc cgacggtgta
     2341 gcgccagccg tcgacggtgg actgctcgcg gctgctgcgc cgccaggcgg acagcgcggg
     2401 cagcacctcg cgcagcgggg cgtcgccggc gaggtcgagg gtggcggcga ggccctcgag
     2461 gtcctcttcg tccaccgtcc gccagaagcg gctgtccacc tcgtcggaga cctcggtggc
     2521 ggtttcggcg gcggtgtccg cggcgcgcag ctcgggccag taccgcatcc gctggaaggc
     2581 gtaggtgggc aggtcgacgc ggtgggcacc ggtgccggcg aagacgcagc gccagtcgac
     2641 gggcaccccg tgggcgtggg cctcggcgag ggaggtcagg aagcggtcca ggccgccgtg
     2701 gtcgcggcgc agggtgccga ggacgacggc gtctgcggcg gcgtcctcga tggtctcgcg
     2761 gaggccgaag ccgacgacgg ggtgcgggga gacctcgatg aaggcccggt ggccggcggt
     2821 gagcaggccg cggaccgcgt cctcgaagcg cacggtctcg cgcaggctcg tgtaccagta
     2881 ggcggcgtcc aggacggtgt cgtcgtcgag ccagtcgccg gtgaccgagg agcggaaggg
     2941 gatctcggcg gggccgggcc gcaggtccgc gagcgcgtcg agcacctggt cccggatggg
     3001 ttcgacgtgg gcggagtggc tgccgtagtc gacggcgacc ttgcgggcct ggacgccctc
     3061 cgcggtcagt tcggtgtaca gctcgtccag ggcgtcggcg gcgccggaga cgacgaccga
     3121 gccggggccg ttgacggcgg cgagggcgag ccggtcgccg tggcgctcca gccggccgcg
     3181 gacctggtcg gcggggagcg gcaccgacat catgccgccg tccccggcga tggcggtgat
     3241 ggccttgctg cgcagtgcgg cgacacgggc gccgtcctcc agggacagga cgccggcgac
     3301 gacggccgcg gcgatctcgc cctggctgtg accgacgacg gcggcgggct cgacgccgtg
     3361 ggtgcgccac aggtgggcga gggagaccat gacggcccac aggacgggct ggacgacgtc
     3421 cacccggtcg aggtcgggcg cgtcggggcc accgcgcagg gccgcggtca gcgaccagtc
     3481 gacatggggg gcgagggcct gctcgcactc ggcgatgcgg tgggcgaact ccggtgcggt
     3541 gtcgagcagt tcacggccca tgccggccca ttgggcgccc tgtccgggga acacgagcac
     3601 gggtccggcg ccgcgccggt cgacgccgcg gaccacgtcg ctgaccatgc cgtccccggc
     3661 gaggtcgcgc aggccgcgct ccagggcgtc gcggtcggcg gcgagcacga ccgcgcggtg
     3721 ctcgaacgcg gtgcgggtgg tggcgaggga cagtcccagg tcggcgaggc cgaggccggg
     3781 gtggtcgcgc aggtgggcga ggagccggcc ggcctgggcc cgcagcccgt cggaggtgcg
     3841 cgcggacagc ggggcgggga cgaggggcag tacccgcgcg ggggcggtgt ccggcgcggc
     3901 ggggccggtc cgctgtgcgc cgccggtggt ggtgtcctgg tgcgcgggct cgtcgggtgc
     3961 ctgctggatg acgacgtgcg cgttggtgcc gctcatgccg aacgaggaga cgccggcccg
     4021 gcgcgggcgg ccggtctccg gccagggcac ggcgtcgtcc agcagcctta cggtgcctgc
     4081 ggaccagtcg acctcggggg tcggggtgcc ggcgtggagg gtggccggga gcagcccgtg
     4141 gcggagggcc atgaccatct tgatgacgcc gccgaccccg gccgccgcct gggcgtggcc
     4201 gatgttggac ttcagggatc ccagccacag cgggcggtcc gcgggccggt cctggccgta
     4261 gacggcgatc agggcctggg cctcgatcgg gtcgcccagc gtcgtgccgg tgccgtgcgc
     4321 ctccacggcg tccacgtcgg tcggggcgag tccgcccgcg gccagcgccg cgcggatcac
     4381 ccgctgctgg gaggggccgt tgggggcggt gaggccgttg gaggcgccgt cctggttgag
     4441 ggcgctgccc tggacgacgg cgaggaccgg gtggccgtgg cgccgggcgt cggagaaccg
     4501 ttcgaggacg atcatgccgg cgccttcggc ccagctggcc ccgtcggcgt ccgcggagaa
     4561 cggcttgcag cggccgtcct cggcgagggc ccgctgccgg ctgaactcga tgagcgagcc
     4621 gggtgtcgac atcacggtga cgccgcccgc cagtgccagg tcgcactcgc cctgccgcag
     4681 cgactgcaca ccgaggtgca gggcgacgag ggaggaggag caggcggtgt cgacggacag
     4741 cgccgggccc tccagtccga gggcgtaggc gatgcggccc gacaggacgc tcggggagtt
     4801 gccggtgccg atgtatccct cgaagctgtc ctcggcggcg ccgaggatgc cgacgtagtc
     4861 ctggtaggtg actccggcga agactccggt gaggctgccg cgctgggacg cggggtcgat
     4921 gccggcccgc tccagtgcct cccaggaggt ctccagcagc agccgctgct gggggtccat
     4981 cgccagcgcc tcgcgtgggg agatgccgaa gaagccgggg tcgaagtggc tggcgtggtg
     5041 caggaagccg ccttcgcggg cgtagcaggt gcccgggtgg tcggggtcgg ggtggtacag
     5101 cttcgccagg tcccagcccc ggtcggtggg gaacggggag atgccgtcgc cgcggtcggc
     5161 caccaggtcc cacagttcct cggggctggt gatgccgccc gggtagcggc aggccatgcc
     5221 gacgacgacg accgggtcgt cgtcgagccg ggcgcgggag gcgacggggg ccgtggtgcc
     5281 ggtggcggcg ccgaagagtt ccgcgtcgag gtgcgcggcg agggcgagcg gggtcgggtg
     5341 gtcgaagacg agggtggcgg gcagcaggac accgaggccg gcgctgagcc ggttgcgcag
     5401 ttcgacggcg gtgacggagg cgaagccgag gtccttgaag acgcggccgg gctcgacctc
     5461 gtccaggtcg acgtagtcca gtacggcggc cacggtacgg cgtaccaggt ccagcagggc
     5521 gcgccgccgc tcggccgcgg accgtcccgc gagccgctcc agcagtcccg taccgtcgcc
     5581 cgggccgtca ccggccccgg agtcgtcggc ggcgcggcgg cgcttcgtgc ggcgcgggtc
     5641 ggtcgacggc aggggtccgc tgcctgcggg gtcctcctgg gtgcgggggc cggccgcggt
     5701 gtccgcgcgg gcgtcggctg cggccgggtc ggtgcgctcg tccggggcca tctggccggt
     5761 gaccgcctgg ccggtgtccg ccgggtcggt gtccgccggg tcgcaggccg tccgggcctg
     5821 tccggccggc gcggggcgca gccgcagcga gtccacggtg aggacgggca ggccggaggc
     5881 gtcggcggcg agcagcgtga gggtgtcccc gccggaccgg gtcagccgga tccgcagcgt
     5941 gccggctccg tgcgcgagga gtgtggcgcg ctgccacgcg aacagcacca gcccgtcacc
     6001 gactccggcc ggcagcccga gccccagcgg gtgcagtgcc gcgtccagca gggccgggtg
     6061 caccccgaac cgcctggccc gctcgcgttc gtcggcgccg agggcgactt cggcgtagac
     6121 gttctcgccg tgccgccaga cggcggtcag cgcccggaac gcggggccgt actccaggcc
     6181 cgggccggcc gcgagccgtt cgtacaggtc gccgatctcg acctgttctg cgccgggcgg
     6241 cggccaggcg gcgaggccgg tctccggccg cccggcggtg gtgccggcgg gcgcgagcag
     6301 gccgccggcg tggcgggtcc acgcggtgcc gtccgacggc gcgccgtcgg ggcgggagtg
     6361 gacggtgacc gcgcgggtgc cccgggcgtc gggttccccg atgcggacct ggagccggac
     6421 cgcgccgcgc tcgggcacgg tcagcggcgc ctccagggtg agttcgcgga cctcgtcgca
     6481 gcccacctgg tcgcccgcgt ggacggcgag ttcgaggaag gcggtgctgg gtacgacggc
     6541 gtggccgccg atccggtggt ccgcgagcca gggatgcgag cgcagcgaca gccgcccggt
     6601 caggacgacc gcgtcgctgt ccgcggccgg cagcgcggcg gtgagcagcg ggtggccggt
     6661 gtcgtcgagg cccagcgcgg aggcgtcatg gggtccggcg ggcacgtcga gccagtagcg
     6721 gcggcgctgg aaggcatagg tgggcagggc ggtccgccgc gcccggccca gggccggtac
     6781 gggtgccgtc cagtcgatgt cggcaccccg cgtgaacagg gccgacacgg cctccagcag
     6841 ggcgcgtgcc tcggggcggt cgtcgcgcag cgcgggcacg tacaggccgt ccgccgcgcc
     6901 cggacaggac tgggccaggg tggtgagggt gctgtcgggg ccgagttcca gccagcgggt
     6961 gacgttctgc ccggcgagcg cgctgacgcc gtcggcgaag cgcaccgcct gccggacgtg
     7021 ccgcacccag tactcggggg aggtcagctc ctcggcggtg gcgggccggc cggtgacgtc
     7081 ggagacgacg gggatacggg gagcggcgta ggacagcgtc tcggcgacgg cgcggaagtc
     7141 ggccagcatc ggttccatca gcggcgagtg gaaggcgtgg ctgacccgca gccgccgggt
     7201 gcgcctgccg agcgcctcga ccgcggcggc gatctcccgc accgcgtcct cggtgcccga
     7261 gaccaccagc gacagcggtc cgttgacggc ggccaccccg gcctcggtct cccggccggc
     7321 cagcagcggc agcacctcct cctcggacgc ctggagcgac accatcgccc cgccctccgg
     7381 cagggcctgc atcagccgtc cacgcgcggc gaccagccgg caggcgtccg ccagtgacca
     7441 cactccggcc gcatgggcgg ccgtcaactc gccgatggag tgcccgagca gcacgtcggg
     7501 gcgtacgccc caggactcca gcagccggaa cagcgccact tcgagggcga acagggcggg
     7561 ctgggcgaac tcggtgcggt tcagcggtcc ggcgtcgtca ccgaagacca cttcccgcag
     7621 cgggcgtggc agttcggtgt ccatgtgcgc gcacacggcg tcgaaggcgt ccgcgaagac
     7681 cgggtaccgc tcgtacagct cccgccccat gcccgggcgc tgcgacccct gaccggcgaa
     7741 caggcacgcg gtgcgcccgt ccgcgaggac ggagccggtg acggtggcgt cggaccgctg
     7801 ccccgaggcg agcgcccgca ggccgccgag cagttcgtcg cgcccggcgc cccagaccac
     7861 ggcgcggtgc tcgaacaccg agcgggaccg cacgagggaa gcggcgatct cggccggggc
     7921 ggtgccggga cgtgcctcgg cgaaggcggc cagccgctcg gcctgggcgc acagcgcggc
     7981 acgcgtgcgg ccggacacca cccacggcag caaaggcggt tcgggcgcgg cggcgtccgg
     8041 tacgccggcc gggtcgtcct cggggaccgg ctcgggtgcg ggctgctcca gcacgacgtg
     8101 cgcgttggtt cccgacacgc cgaaggcgga gacgccggcg cggcggggcc gtccctcggt
     8161 ccgcggccac tccacgttct ccgtcagcag cgcgatgtcg ccggccgacc agtccacgtg
     8221 cgacgacggc cgctccgcgt gcagcgtgcg cggcagcacc ccgtgccgca tggcgagcac
     8281 cgtcttgatg acgccggcga cgcctgcggc ggcctgcgtg tgaccgatgt tggacttcaa
     8341 cgaccccagg tacagcggcc gttcgcggtc ctggccgtag gtggcgagca gggcctgcgc
     8401 ctcgatcggg tcgcccaggg tggtgccggt gccgtgcgcc tcgacggcgt ccacgtcggc
     8461 cggggtgagc ccggcgccgg cgagcgcctg ccggatcacc cgctgctggg cgggcccgtt
     8521 gggggcggtc aggccgttgg aggcgccgtc ctggttgacc gccgagccgg cgatcacggc
     8581 gagtacgtcg tgtccgttgc ggcgggcgtc ggagaggcgt tcgacgacga gcacgcccac
     8641 gccctcggcc cagccggtgc cgtcggcgtc gtcggagaac gccttgcagc ggccgtccgc
     8701 ggccagcccg ccctgcgcgc tgaactccac gaacgcggcc gggtcggcga gcaccgtgac
     8761 cccgccgacc agggcgaggt cgcactcggc ggagcgcagg gactgtgcgg ccaggtgcag
     8821 cgcgacgagg gaggacgagc acgcggtgtc gacggtgacc gccgggccct cgaaaccgaa
     8881 ggtgtaggcg acgcggccgg agaccacgct gcccgcgaca ccggtcagca gctgcccgtc
     8941 gagtccttcg ggcacctcgc gcaggcccgc gccgtatccg gagccgccgg cgccgacgaa
     9001 gacgcccgta cggctgccgc gcagcgagtc gggccggatc gcggcgtgct ccagcgcctc
     9061 ccaggaggct tcgagaagca gcctctgctg ggggtcgacc gcgagggcct cgcggggcga
     9121 gatgccgaag aaaccggggt cgaactgcgc ggcgtcggcg aggaagccgc ccgcgcgggt
     9181 gtggctgcgg ccctggcccg cgccgtcggg ggaaccgtgc agcgcgtcga ggtcccagcc
     9241 gcggtcggcg gggaactccg agatggcgtc ggcgccttcg gagaccaggc gccacaggtc
     9301 gtcgggcccg gacacaccgc cggggagccg gcaggccatg ccgacgacga ccaccgggtc
     9361 gtccgtggtc gaggtgacgg ccgggacggg ctgccgggtg tcggtgccgc ggccgtcgtc
     9421 gtcctcaccg agcagttcgc gccggagcag ccggaccagg gcggccggag tcgggtggtc
     9481 gaagacgagg gtgctgggca gtttcaggcc ggtctcggcg gagagccggt tgcgcagctc
     9541 cacggccgtg agggagtcga agccgaggtc gcggaaggac cgggtggcct ccaccgctcc
     9601 ggcgtccgcg tgcccgagca ccgcggcggc accggtccgc accaactcca gcagccggcg
     9661 gtcgcgttcg gcccgggaca ggtcggcgag ccgttcacgc agggccgtgc cggacgccac
     9721 ggcggaggcg gtggcgacg
//
