LOCUS       NZ_KQ948874            18475 bp    DNA     linear   CON 21-APR-2024
DEFINITION  Streptomyces bungoensis strain DSM 41781 PRJNA299233_s024, whole
            genome shotgun sequence.
ACCESSION   NZ_KQ948874
VERSION     NZ_KQ948874.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces bungoensis
  ORGANISM  Streptomyces bungoensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 115451)
  AUTHORS   Ruckert,C., Winkler,A., Kalinowski,J., Kampfer,P. and Glaeser,S.
  TITLE     Draft genome sequence of Streptomyces bungoensis DSM 41781, type
            strain for the species Streptomyces bungoensis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 115451)
  AUTHORS   Ruckert,C., Winkler,A., Kalinowski,J., Kampfer,P. and Glaeser,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-OCT-2015) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 13-OCT-2014
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 60.6x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001514215.1-RS_2024_04_21
            Annotation Date                   :: 04/21/2024 02:15:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,539
            CDSs (total)                      :: 7,454
            Genes (coding)                    :: 7,226
            CDSs (with protein)               :: 7,226
            Genes (RNA)                       :: 85
            rRNAs                             :: 1, 1 (5S, 16S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            tRNAs                             :: 80
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 237
            CDSs (without protein)            :: 228
            Pseudo Genes (ambiguous residues) :: 0 of 237
            Pseudo Genes (frameshifted)       :: 67 of 237
            Pseudo Genes (incomplete)         :: 196 of 237
            Pseudo Genes (internal stop)      :: 10 of 237
            Pseudo Genes (multiple problems)  :: 43 of 237
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:26:42
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 96976
            Orig. end                         :: 115451
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KQ948874.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..18475
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..18475
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..18475
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:16729](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16729
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(48..62)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.74"
                     /tool="antismash"
     gene            complement(324..1265)
                     /locus_tag="AQJ66_RS32925"
                     /old_locus_tag="AQJ66_32920"
     CDS             complement(324..1265)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009339288.1"
                     /locus_tag="AQJ66_RS32925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_32920"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_061929270.1"
                     /transl_table=11
                     /translation="MGAGHDHGHTHSHAPPTGTATAAYRGRLRITLGITLMIMVVEIAG
                     GLVADSLALIADAAHMATDAVGLGMALLAIHFAGRPASTKRTFGYARAEILAALANCVL
                     LLGVGGYVLYEAVQRFVTPADTHGGLMIVFGVVGLVGNSVSLLLLMRGQQESLNVRGAF
                     LEVAADALGSVAVLVSATVILLTGWQAADPVASLAIGLMIVPRTVKLLRETLDVLLEAA
                     PKNVDMAEVRTHILALDGVEDVHDLHAWTITSGMPVLSAHVVVSSEVLNAIGNEKMLHE
                     LQGCLGDHFDVEHCTFQLEPGGHAEHEARLCH"
     misc_feature    1342..1356
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            complement(1404..2375)
                     /gene="galE"
                     /locus_tag="AQJ66_RS32930"
                     /old_locus_tag="AQJ66_32925"
     CDS             complement(1404..2375)
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (66-207). E-value:
                     6.9e-12. Score: 36.9. Matches aSDomain:
                     nrpspksdomains_AQJ66_RS32930_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676194.1"
                     /locus_tag="AQJ66_RS32930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_32925"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_061929272.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 9.8e-20, bitscore:
                     63.4, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 5.5e-12,
                     bitscore: 38.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVARAMAGAGESVVALDDLSAAVPARLPADV
                     PLVEGSTLDGDLLKRVLAEYGVTGVVHLAARKQVAESVARPTRYYRENVEGLATLLDAI
                     AEAGVTRLLFSSSAAVYGNPDVDLITEDTPCAPVNPYGETKLAGEWLVRAAGRAHGIST
                     VCLRYFNVAGAAAPELADTGVFNIVPMVFDRLTRDEAPRIFGDDHPTPDGTCVRDYIHV
                     ADLAEAHLAAARRLDGGAPAGDLTLNVGRGEGVSVREMVTVIGEVTGDRRPAVVEGRRP
                     GDAPRAVASAARAAEALGWRARRGVPEMIESAWAGWRLHHGL"
     aSDomain        complement(1755..2177)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AQJ66_RS32930_NAD_binding_4.1"
                     /evalue="6.90E-12"
                     /label="AQJ66_RS32930_NAD_binding_4.1"
                     /locus_tag="AQJ66_RS32930"
                     /protein_end="207"
                     /protein_start="66"
                     /score="36.9"
                     /tool="antismash"
                     /translation="VTGVVHLAARKQVAESVARPTRYYRENVEGLATLLDAIAEAGVTR
                     LLFSSSAAVYGNPDVDLITEDTPCAPVNPYGETKLAGEWLVRAAGRAHGISTVCLRYFN
                     VAGAAAPELADTGVFNIVPMVFDRLTRDEAPRIFGDD"
     CDS_motif       complement(2304..2372)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQJ66_RS32930_0001"
                     /evalue="6.40E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="AQJ66_RS32930"
                     /protein_end="24"
                     /protein_start="1"
                     /score="18.8"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVARAMAGAG"
     gene            2651..4438
                     /locus_tag="AQJ66_RS32935"
                     /old_locus_tag="AQJ66_32930"
     CDS             2651..4438
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="AQJ66_RS32935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_32930"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_061929274.1"
                     /transl_table=11
                     /translation="MSTAIVTGQPVPGSSLEHDLRSLGFDVCVAGDAAEAETLLAAVPA
                     DRRVALVDARFVGHPHALRLGLTDPRFPLSAVPGAVTAQPAARPALTRALARETSAGGG
                     TAVAVGSLADRAVTALAADGAEVHRPELGSLVAVVPADPQARNEARQAVAAVDDEAVRL
                     KSAVKSRDGFFTTFFISPYSRYLARWCARRGLTPNQVTTASLLTALVAAGCAATGTRAG
                     FVAAGVLLIASFVLDCTDGQLARYALKYSTLGAWLDATFDRAKEYAYYAGLALGAARGG
                     DDVWALALGAMVLQTCRHVVDFSFNEANHDATANTSPTAALSDRLDGVGWTVWVRRMIV
                     LPIGERWAMIAVLTAATTPRVTFYALLAGCAFAATYTTAGRVLRSVTRKARRTDRAAQA
                     LADLADNGPLATFVARVTPGRLGAAPLVALAGTAVLAVSLFSGVTWAPVAGAVVYAIAS
                     GQALYRPLKGPLDWLLPPLFRAAEYGTVLVLAARAGVNGALPAAFGLVAAVAYHHYDTV
                     YRIRGNAGAPPAWLVRSIGGHEGRTLLVTVLAAVLTASQFKVALTVLAVAVALVVLAES
                     IRFWVSAGAPAVHDEGEPA"
     gene            4435..5187
                     /locus_tag="AQJ66_RS32940"
                     /old_locus_tag="AQJ66_32935"
     CDS             4435..5187
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="AQJ66_RS32940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_32935"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_061929276.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1e-11, bitscore:
                     38.0, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVGPAGVEGEPTVLDLTLG
                     NFAEIGLTEVAVIVGYRKEAVYARKEALEQKYGLKLTLIDNDKAEEWNNAYSLWCGRDA
                     LKDGVILANGDTVHPVSVEKTLLAARGEGRRIILALDTVKSLADEEMKVVVDPAKGVQK
                     ITKLMDPAEATGEYIGVTLIEGDAAPELADALKTVWETDPQQFYEHGYQELVNRGFRID
                     VAPIGDVQWVEIDNHDDLARGREIACLY"
     gene            5175..6236
                     /locus_tag="AQJ66_RS32945"
                     /old_locus_tag="AQJ66_32940"
     CDS             5175..6236
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494151.1"
                     /locus_tag="AQJ66_RS32945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_32940"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_061929278.1"
                     /sec_met_domain="Fe-ADH (E-value: 2.8e-26, bitscore: 84.7,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 3.4e-12, bitscore:
                     38.7, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLLTRLIPSPVVVDIRPGALDDLGAVLADERIAQSGRLAVAVSG
                     GSGSKLRERIAPSLPGASWYEVGGGTLDDAIRLAGEMKSGRYDAVVGLGGGKIIDCAKF
                     AAARVGLPLVAVPTNLAHDGLCSPVATLDNDAGRGSYGVPNPIAVVIDLDVIREAPARY
                     VRAGIGDAISNVNAIADWELSNRVNGEKIDGLAAAMARQAGEAVLRHPGGIGDNEFLQV
                     LAEALVLSGIAMSVSGDSRPSSGSCHEINHAFDLLFPKRAAAHGEQCGLGAAFAMYLRG
                     AHEEAAHMAEVLRRHGLPVLPEEIGFSVDEFVSAVEFAPETRPGRYTILEHLDLKPNQI
                     KDTYADYVKAIGS"
     gene            6214..6993
                     /locus_tag="AQJ66_RS32950"
                     /old_locus_tag="AQJ66_32945"
     CDS             6214..6993
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413838.1"
                     /locus_tag="AQJ66_RS32950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_32945"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_079060562.1"
                     /transl_table=11
                     /translation="MSRPSVAELRPVVHPAGVKDRRSGEHWAGRLYMREVSLRVDRYLV
                     NTRVTPNQLTYLMTVCGVLAAPALLVPGIAGAVLGVVATQLYLLLDCVDGEIARWKKQY
                     SLGGVYLDRVGAYLTDAAVLVGLGLRAADLWGGGRIDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQTGKPPVQESAAEPRSSGMALARRAASALKFHRLILGIEASLLIVVLAVADQ
                     IRGDLFFTRLGTAVLAGIALVQTLLHLVSILASSRLR"
     gene            7038..7883
                     /locus_tag="AQJ66_RS32955"
                     /old_locus_tag="AQJ66_32950"
     CDS             7038..7883
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031159.1"
                     /locus_tag="AQJ66_RS32955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_32950"
                     /product="glycosyltransferase"
                     /protein_id="WP_061929326.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 7.9e-12,
                     bitscore: 38.0, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNRPEELRALLDSVARQDGDPVEVVVVGNGSPVPDVPAGVRTVE
                     LPENLGIPGGRNVGIEAFGPGGQDVDVLLFLDDDGLLARQDTAQLCREAFAADPELGII
                     SFRIADPDTGVTQRRHVPRLRASDPLRSSRVTTFLGGANAVRTRVFAEVGGLPDEFFYA
                     HEETDLAWRALDAGWLIDYRADMVLHHPTTAPSRHAVYHRMVARNRVWLARRNLPALLV
                     PVYLGVWLLLTLARRPSGPALKAWFGGFREGWATPCGPRRPMRWRTVWRLTRLGRPPVI
                     "
     gene            7963..8892
                     /locus_tag="AQJ66_RS32960"
                     /old_locus_tag="AQJ66_32955"
     CDS             7963..8892
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994380.1"
                     /locus_tag="AQJ66_RS32960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_32955"
                     /product="ABC transporter permease"
                     /protein_id="WP_061929282.1"
                     /transl_table=11
                     /translation="MSETTHDGRVAVTAAPSPDEGLTAERLAARYGLAVSGARPSLAEY
                     VRQLWGRRHFILAFSQAKLTAQYSQAKLGQLWQVATPLLNAGVYYFIFGVILHASRGMS
                     QDVYIPFLVTGVFVFTFTQSSVMSGVRAISGNLGLVRALHFPRASLPISFSLQQLQQLL
                     FSMIVMFVVAIGFGSYPGPSWLLIVPVLVLQFLFNTGLALIVARMGAKTPDLAQLMPFI
                     LRTWMYASGVMFSISKMMEGRSELAVRLLQVNPAAVYMDLMRFALIDGYGASNLPPHVW
                     AIALFWAVVVFAGGFVYFWKAEERYGRG"
     gene            8885..9673
                     /locus_tag="AQJ66_RS32965"
                     /old_locus_tag="AQJ66_32960"
     CDS             8885..9673
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004922385.1"
                     /locus_tag="AQJ66_RS32965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_32960"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_061929285.1"
                     /transl_table=11
                     /translation="MAEHTPQVEADRRPTVIADDLHIVYRVNGARTGKGSATSALSRIL
                     RRGEERGVRKVHAVRGVSFVAYRGEAIGLIGSNGSGKSTLLRAIAGLLPAERGKVYTDG
                     QPSLLGVNAALMNDLTGERNIILGGLAMGMSREEVKERYQGIVDFSGINEKGDFITLPM
                     RTYSSGMAARLRFSIAAAKDHDVLMIDEALATGDRKFQKRSEERIRELRKEAGTVFLVS
                     HNNKSIRDTCNRVLWLERGELRMDGPTEEVLKEYEKFTGK"
     gene            10001..10927
                     /gene="hpnC"
                     /locus_tag="AQJ66_RS32970"
                     /old_locus_tag="AQJ66_32965"
     CDS             10001..10927
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019527751.1"
                     /locus_tag="AQJ66_RS32970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_32965"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_107119111.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.8e-42, bitscore:
                     138.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.3e-41,
                     bitscore: 135.4, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCRPRPGQRAVTAPRTAPDLERATLDKAASENFPVAPFFLPRAWR
                     DDLMAVYGFARLVDDIGDGDLAPGGADAHALGVSATDAGDRLVLLDAFETDLRRVFDGT
                     PRHPLLRRLQPTVRRRALTPEPFLGLIAANRQDQLVTRYETYDDLLAYCELSANPVGRL
                     VLAVTGTATPERIRLSDAICTALQIVEHLQDVAEDLGRDRIYLPAEDMKRFHVQETDLA
                     AKITGASTRALVAYEAQRARDLLNEGAPLVGSVHGRLKLLLAGFVAGGRAAIDAIAATE
                     FDVLPGPPKPGKVQLLREVGVTLRGER"
     gene            10924..11874
                     /gene="hpnD"
                     /locus_tag="AQJ66_RS32975"
                     /old_locus_tag="AQJ66_32970"
     CDS             10924..11874
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972236.1"
                     /locus_tag="AQJ66_RS32975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_32970"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_061929289.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.9e-56, bitscore:
                     182.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 7.4e-70,
                     bitscore: 228.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTVDSPPHVSAPVLAAYSYCEAVTGQQARNFAYGIRLLPAPKR
                     RAMSALYALSRRVDDIGDGTLPDEVKLARLEDTRALLTRIRDGEVAEDDTDPVAVALTH
                     AAGAFPIPLGGLDELIDGVQMDVRGETYETWDDLKVYCRCVAGAIGRLSLGVFGTEPGA
                     RGAERAPEYADTLGLALQLTNILRDVREDAEGGRTYLPADDLAKFGCSAGFRGPTPPEG
                     SDFAGLVHFEVRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIERDPEAVLR
                     GRVSLPGREKAYVAVRGLSGLDTRHVSRHTVRRRA"
     gene            12026..13453
                     /gene="hpnE"
                     /locus_tag="AQJ66_RS32980"
                     /old_locus_tag="AQJ66_32975"
     CDS             12026..13453
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006133315.1"
                     /locus_tag="AQJ66_RS32980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_32975"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_061929290.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2e-08, bitscore:
                     26.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDGSRPAPAHAGTPAAPGRSAVVVGGGLAGVTAALALADAGVHV
                     TLLEGRPRLGGLAFSFRRGDLTVDNGQHVYLRCCTAYRWFLERIGGTALAPLQDRLDVP
                     VVDAAKPEGRRLGRLRRDPLPVPLHLGRSLAAYPHLSLTERAAVGRAALALKGLDLTDP
                     ALDTQDFGSWLAAHGQSARAVEALWDLVGVATLNAVAGDASLALAAMVFKTGLLSDPGA
                     ADIGWARVPLGELHDRLARKALDSAGVRTEVRARVTSLSTNDNGSWNVQVPGETLRADA
                     VVLAVPQREAHGLLPPGALDAPERLLGIGTAPILNLHVVYDRTVLARPFFAALGTPVQW
                     VFDRTDASGLRAGQYLAVSQSAARDDIDAPVAVLRERYLPELERLIPGTRRAVVEDFFV
                     TRERTATFAPVPGVGRLRPGARTRVPGLYLAGAWTATGWPATMESAVRSGVSAADAALS
                     ALGRPRPRHLFEFEEAA"
     gene            13453..14589
                     /locus_tag="AQJ66_RS32985"
                     /old_locus_tag="AQJ66_32980"
     CDS             13453..14589
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386166.1"
                     /locus_tag="AQJ66_RS32985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_32980"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_079060561.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.7e-59, bitscore:
                     192.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDQHSPVGPRTPGTATRGETVPTVPPAPTPAPRAAVDVTALLER
                     GRTLATPVLRAAVDRLAPPMDTVAAYHFGWIDAAGNPADGDGGKAVRPALAVLSAEVTG
                     AAPEVGVPGAVAVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALA
                     NEVLLELGTVEAGRATRRLTTATRALIDGQAQDISYEHRDRVSVEECLEMEGNKTGALL
                     AASSSIGAVLGGADDATADALERYGYHLGLAFQAVDDLLGIWGDPEATGKQTWSDLRQR
                     KKSLPVVAALAAGGDASERLGEILAADAKSSDFENFSEEEFAARAALIEEAGGREWTAG
                     EARRQHTIAIEALDAVRMPDRVRAAFTALADFVVVRKR"
     gene            14705..16729
                     /gene="shc"
                     /locus_tag="AQJ66_RS32990"
                     /old_locus_tag="AQJ66_32985"
     CDS             14705..16729
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676206.1"
                     /locus_tag="AQJ66_RS32990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_32985"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_061929293.1"
                     /sec_met_domain="T2TS (E-value: 6.2e-153, bitscore: 502.7,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGATLPPRAAAASDTAITTPAAAGARQAAEHAAQRAT
                     DFLLARQDVEGWWKGDLETNVTMDAEDLLLRQFLGIQDDSTTQAAALFIRGEQREDGTW
                     ATFYGGPGELSTTVEAYVALRLAGDAPDAPHMAKAAAWIRERGGIAAARVFTRIWLALF
                     GWWKWEDLPELPPELIWFPTWFPLNIYNFGCWARQTIVPLTVVSAKRPVRPAPFALDEL
                     HTDPANPNPPQPLAPLASWDGLFQRLDKVVRGYRRVAVRGLRRAAMNSAARWIIERQEN
                     DGCWGGIQPPAVYSVIALHLLGYDLEHPVMREGLASLDRFAVWREDGARMIEACQSPVW
                     DTCLATIALADAGLPADHPQLVKAADWMLGEEIVRPGDWAVRRPGLPPGGWAFEFHNDN
                     YPDIDDTAEVALALRRVRHHDPERVDKAIGRGVRWNLGMQSKNGGWGAFDADNTSPFPN
                     RLPFCDFGEVIDPPSADVTAHVVEMLAAEGLAHDPRTRRGIAWLLAEQEPDGSWFGRWG
                     VNYLYGTGSVVPALTAAGLPGSHPAIRRAVSWLEGVQNDDGGWGEDLRSYKYAGEWSGR
                     GASTASQTAWALMALLAAGEKDSKAVERGIQWLAGTQRADGSWDEPYFTGTGFPWDFSI
                     NYHLYRQVFPLTALGRYLHGDPFERNLLARKPLPEGKGG"
     gene            16732..17373
                     /locus_tag="AQJ66_RS32995"
                     /old_locus_tag="AQJ66_32990"
     CDS             16732..17373
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431357.1"
                     /locus_tag="AQJ66_RS32995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_32990"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_061929295.1"
                     /transl_table=11
                     /translation="MSKQPAPAPLLIACALGIEHLALRTGDRSGADGPVTFVRTGMGPR
                     AAERSLTRHLAEPALTEAAVLATGFCAGLAPGMHPGDLVVAEETRDPRGSVACLGTELL
                     VKELVRILPGRTVHTGPLTGSDHVVRGTERSDLRATGAIAVDMESAATLLSAVRAGERP
                     VAAVRVVVDTPEHELVRIGTVRGGISALRVLRRVLPAFFEWHRSLLLPRR"
     gene            17379..18401
                     /gene="hpnH"
                     /locus_tag="AQJ66_RS33000"
                     /old_locus_tag="AQJ66_32995"
     CDS             17379..18401
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386169.1"
                     /locus_tag="AQJ66_RS33000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_32995"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_061929297.1"
                     /sec_met_domain="PF04055 (E-value: 1e-19, bitscore: 64.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 2.2e-10, bitscore: 33.0,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSIKVATYLAEQKLRRRDKFPLIVELEPLFACNLKCEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVAKRKYVF
                     LCTNAMLLRKKIDKFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVEAIKEAKRRGF
                     RVTTNSTFFNTDTPQTVVEVLNFLNDDLQVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FRKAFSGGNRGRWRLNHSPLFLDFLEGKVDFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRELVEDTDWDKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAMRETVSGNRE
                     "
ORIGIN
        1 gcggcgagct tctccgcggt gccgatcgtc acgcccttct cgtcgaccag ttccagcaaa
       61 atcgcctctg cggtgccgtt cgacgagctg tgcgtctcgg tggcaggtgt gatcggcata
      121 cccatccttc gcctcggtct tcgcacccca agtctgccgt acgaatccgg cactaacggc
      181 acttcccgca cctccgcatg tcccgcgcgg ggcggtgccg cagggggact cggtagatca
      241 tcgtgcccgg ccgccgggcc ccggaaccgt ccgggggtgc gccgaacagg tgtccgggac
      301 gccggtccgt acggtcggtc gcgtcagtgg cagagccgcg cctcgtgctc cgcgtgtccg
      361 cccggttcca gctggaacgt gcagtgctcc acgtcgaagt ggtcgccgag gcagccctgc
      421 agctcgtgca gcatcttctc gttgccgatg gcgttcagca cctcggagct gaccaccacg
      481 tgcgcggaga gcacgggcat gccggaggtg atcgtccacg cgtgcaggtc gtggacgtcc
      541 tccacgccgt ccagcgccag gatgtgcgtc cggacctccg ccatgtcgac gttcttcggc
      601 gccgcctcca gcagcacgtc cagcgtctcg cgcagcagct tcaccgttct cggtacgatc
      661 atcagcccga tggccagcga ggcgacgggg tcggccgcct gccagccggt gagcaggatc
      721 acggtcgccg agaccagcac cgccaccgag cccagcgcgt ccgcggccac ctccaggaag
      781 gcgccgcgca cgttcaggct ctcctgctgc ccgcgcatca gcaggagcag cgagacgctg
      841 ttgccgacca ggccgaccac accgaacacg atcatcagcc cgccgtgggt gtccgcgggc
      901 gtgacgaacc gctggaccgc ctcgtacagg acgtacccgc cgacgccgag cagcagcacg
      961 cagttggcca gggccgcgag gatctcggcg cgggcgtacc cgaaggtgcg cttggtgctc
     1021 gccgggcggc ccgcgaagtg gatggcgagc agggccatgc cgaggcccac cgcgtcggtc
     1081 gccatgtggg ccgcgtccgc gatcagggcg agcgagtccg cgacgagccc gccggcgatc
     1141 tcgaccacca tgatcatcag ggtgatgccg agcgtgatcc gcagccggcc cctgtacgcg
     1201 gcggtggccg tccccgtggg cggcgcgtgg gagtgcgtgt gcccgtggtc gtgccctgcc
     1261 cccatgagga gaccgccctt tcgcatcttc cgcccgggct cacagtgaac tacgggggcg
     1321 gggtatcggg caacgcggca ctgaacaccg ttgtcatgtg ccctgacctg cggaaacgat
     1381 gcgcaggtca gggaggtgcc gcctcacagg ccgtggtgca gccgccagcc cgcccaggcc
     1441 gactcgatca tctccgggac cccgcgccgg gcccgccagc ccagcgcctc ggcggcccgc
     1501 gcggccgagg cgaccgcgcg cggcgcgtcg cccgggcggc gcccctccac caccgccggc
     1561 cgccggtcgc cggtgacctc gccgatcacc gtgaccatct cgcgcacgga gacgccctcc
     1621 ccgcggccga cgttcagcgt cagatcaccc gccggggcgc ctccgtccag ccgccgcgcg
     1681 gcggccaggt gcgcctcggc gaggtcggcc acgtggatgt agtcgcggac gcaggtgccg
     1741 tccggcgtcg gatggtcgtc gccgaagatc cgcggcgcct cgtcgcgggt gagccggtcg
     1801 aagaccatcg gcacgatgtt gaacaccccg gtgtccgcca gttccggtgc cgcggccccc
     1861 gccacgttga agtagcgcag gcacaccgtg gagatcccgt gcgcccgccc ggccgcccgc
     1921 accagccact ccccggccag cttcgtctcg ccgtaggggt tcaccggcgc gcacggggtg
     1981 tcctcggtga tcaggtccac gtccgggttg ccgtacacgg ccgccgacga ggagaacagc
     2041 agccgtgtga cccccgcctc ggcgatcgcg tccagcaggg tggcgaggcc ctccacgttc
     2101 tcccggtagt agcgggtggg ccgcgccacg gactcggcga cctgcttgcg cgccgcgagg
     2161 tggaccacgc ccgtcacgcc gtactccgcg aggacgcgct tgagcaggtc cccgtccagg
     2221 gtcgagccct ccacgagcgg cacgtccgcc gggagccgtg cgggcacggc ggccgacagg
     2281 tcgtccagcg ccacgacgct ctctccggcg ccggccatgg cccgagccac atgcgccccg
     2341 atgtatccgg ctccgccggt gatcagccac gtcatggtcg cccaccctat gccgcgccgg
     2401 ccgtgtgtcc ggtctgccgg gcctgcccgg gtctggggcc gccatttgtg gggcgggccc
     2461 cggatcagcg aggatgatcg cggcaaaggc ccgggcagcc gccgtggacc ggaccgtgaa
     2521 cggccggtga acacgggctc cgacccatcc gataccctct gccgacatgc cgcccgggtg
     2581 ccgcaggcag ggcgtcccac cacgcaagag accggcgcgc cgcgcgccgg cgcccaggga
     2641 gtgagttcgg ttgtcgaccg ccatcgtcac cggtcagccg gtccccggat cgtcgctcga
     2701 acacgatctg cggtccctcg gcttcgacgt gtgcgtggcc ggcgacgccg ccgaggcgga
     2761 gaccctgctc gcggccgtgc ccgccgaccg gcgggtggcc ctggtcgacg cccgcttcgt
     2821 cggccacccg cacgccctgc gcctaggcct caccgacccg cgcttcccgc tctccgccgt
     2881 ccccggcgcc gtcaccgccc agcccgccgc ccggccggcg ctgacccggg ccctggcccg
     2941 ggagacctcc gcgggcgggg gcacggcggt cgccgtcggc agcctggccg accgcgcggt
     3001 caccgccctc gccgccgacg gcgccgaggt gcaccgcccc gagctgggca gtctggtcgc
     3061 cgtcgtcccg gccgacccgc aggcccgcaa cgaggcccgg caggcggtcg ccgccgtcga
     3121 cgacgaggcc gtccgcctga agtcggccgt gaagtcccgc gacggcttct tcaccacgtt
     3181 cttcatcagc ccctactcgc gctacctcgc gcgctggtgc gcccgccgcg gcctgacccc
     3241 caaccaggtc accaccgcct cgctgctcac cgcgctcgtc gccgccggct gcgcggccac
     3301 cggcacccgg gccggcttcg tcgcggccgg cgtgctgctg atcgcctcct tcgtgctgga
     3361 ctgcaccgac ggccagctcg cccgctacgc cctgaagtac tccacgctcg gcgcctggct
     3421 cgacgccacc ttcgaccggg ccaaggagta cgcctactac gcgggcctcg ccctcggcgc
     3481 ggcccgcggc ggcgacgacg tctgggcgct ggcgctgggc gcgatggtcc tgcagacctg
     3541 ccggcacgtg gtcgacttct ccttcaacga ggccaaccac gacgcgaccg ccaacaccag
     3601 ccccaccgcc gccctctccg accggctcga cggcgtcggc tggacggtgt gggtgcggcg
     3661 gatgatcgtc ctgccgatcg gcgagcgctg ggccatgatc gccgtcctga cggcggccac
     3721 gaccccgcgc gtcaccttct acgcgctgct tgccggatgc gccttcgccg cgacgtacac
     3781 gacggcgggc cgggtgctgc ggtcggtgac gcgcaaggcc cggcgcaccg accgggcggc
     3841 gcaggcgctg gccgacctcg cggacaacgg gccgctcgcc acgttcgtcg cgcgcgtcac
     3901 cccgggccgt ctcggcgccg cgccgctggt ggccctggcc ggcacggccg tcctcgcggt
     3961 gtccctcttc tccggggtga cctgggcgcc cgtcgccggt gccgtggtct acgcgatcgc
     4021 gtcgggacag gcgctgtacc gccccctcaa gggccccctc gactggctcc tgcctccgct
     4081 gttccgggcc gccgagtacg gcaccgtcct cgtcctcgcc gcccgggccg gggtgaacgg
     4141 agcccttccc gcggctttcg gcctggtggc ggcggtcgcc taccatcact acgacacggt
     4201 gtaccgcatc cgcggcaacg ccggagcgcc ccccgcctgg ctggtgcgct ccatcggggg
     4261 gcacgagggg cggacgctac tggtcaccgt cctcgccgcg gtgctcaccg cctcacagtt
     4321 caaggtcgcg ctcacggtgc tcgccgtggc cgtcgccctc gtggtgctcg ccgagagcat
     4381 ccgcttctgg gtgtccgccg gggcgcccgc agtacacgac gaaggagaac ccgcatgatc
     4441 ggcctcgtgc tggcggccgg cgccggaagg cgtctgcgcc cctacaccga caccctgccc
     4501 aaggctctgg tgccggtggg ccccgccggc gtcgagggcg agcccacggt tctggacctc
     4561 accctcggca acttcgccga gatcggcctc accgaggtgg cggtcatcgt cggttaccgc
     4621 aaggaggccg tctacgcgcg caaggaggcg ctggagcaga agtacggcct caagctcacc
     4681 ctgatcgaca acgacaaggc cgaggagtgg aacaacgcct actccctgtg gtgcggccgt
     4741 gacgccctca aggacggcgt gatactcgcc aacggcgaca ccgtgcaccc ggtctccgtc
     4801 gagaagaccc tgctcgccgc acgcggcgag ggcaggagga tcatcctcgc gctggacacc
     4861 gtgaagtccc tcgccgacga ggagatgaag gtcgtcgtgg accccgccaa gggcgtccag
     4921 aagatcacga agctgatgga cccggccgag gccaccggcg agtacatcgg tgtcaccctc
     4981 atcgagggcg acgccgcccc cgagctggcc gacgcgctga agacggtctg ggagaccgac
     5041 ccgcagcagt tctacgagca cggctaccag gagctggtca accgcggctt ccgcatcgac
     5101 gtggcgccca tcggcgacgt ccagtgggtc gagatcgaca accacgacga cctcgcccgc
     5161 ggacgggaga tcgcgtgcct ctactgaccc ggctcatccc ctcgccggtc gtcgtggaca
     5221 tccgcccggg tgccctggac gacctgggag ccgtactcgc cgacgaacgc atcgcccagt
     5281 ccggccggct cgccgtcgcg gtcagcggcg gctccggctc gaagctgcgc gagcgcatcg
     5341 ccccctccct gcccggcgcc tcctggtacg aggtaggcgg cggcaccctc gacgacgcga
     5401 tccggctggc cggcgagatg aagtccggcc gctacgacgc ggtggtcggg ctcggcggcg
     5461 gcaagatcat cgactgcgcc aagttcgcgg cggcccgtgt cggcctgccg ctggtcgccg
     5521 tccccaccaa cctcgcccac gacggcctgt gctcgccggt cgcgaccctc gacaacgacg
     5581 cgggccgcgg ctcctacggc gtgcccaacc cgatcgcggt ggtcatcgac ctggacgtca
     5641 tccgcgaggc ccccgcccgg tacgtccggg ccggcatcgg cgacgcgatc tccaacgtca
     5701 acgcgatcgc ggactgggag ctgtccaacc gcgtcaacgg cgagaagatc gacggcctgg
     5761 ccgccgccat ggcccggcag gccggcgagg cggtgctgcg ccaccccggc ggcatcggcg
     5821 acaacgagtt cctccaggtc ctcgccgagg cactggtcct cagcggcatc gcgatgtcgg
     5881 tgtcgggcga ctcccgcccg tcctccggct cctgccacga gatcaaccac gccttcgacc
     5941 tgctgttccc caagcgggcg gccgcccacg gcgagcagtg cggcctgggc gcggccttcg
     6001 cgatgtacct gcgcggcgcg cacgaggaag cggcgcacat ggccgaggtg ctgcgccggc
     6061 acgggcttcc ggtgctgccg gaggagatcg gcttcagcgt ggacgagttc gtctccgccg
     6121 tcgagttcgc cccggagacc cggcccggcc gctacaccat cctcgaacac ctcgacctca
     6181 agccgaacca gatcaaggac acctacgccg actatgtcaa ggccatcggt agctgaactc
     6241 cggccggtcg tccaccccgc cggggtgaag gaccggcgca gcggtgagca ctgggcggga
     6301 cgcctctaca tgcgcgaggt gtccctgcgc gtcgaccgct acctggtgaa caccagggtc
     6361 acgcccaacc agctcacgta cctgatgacc gtctgcggcg tgctcgcggc cccggccctg
     6421 ctggtgccgg ggatcgcggg cgccgtgctc ggcgtcgtcg ccacccagct gtacctgctg
     6481 ctggactgcg tcgacggcga gatagcgcgg tggaagaagc agtactccct cggcggggtc
     6541 tacctcgacc gggtcggcgc ctacctcacc gacgcggccg tgctggtggg tctcgggctg
     6601 cgcgccgccg acctgtgggg cggcggccgc atcgactggc tgtgggcctt cctcggcacc
     6661 ctggccgcgc tcggcgccat cctgatcaag gcggagaccg acctggtcgg cgtcgcccgg
     6721 caccagaccg ggaagccccc ggtgcaggag tcggccgccg agccgcgctc ctccggtatg
     6781 gcgctcgccc gccgggccgc ctccgcgctg aagttccacc ggctgatcct cggcatcgag
     6841 gcgtccctgc tgatcgtggt cctcgcggtc gcggaccaga tccgcggcga cctgttcttc
     6901 acccggctgg gcaccgccgt cctcgccggc atcgccctgg tgcagaccct cctgcacctg
     6961 gtgtccatcc tcgcgtccag caggctgagg tgagtgccgt ggcttcatcc ctcaaggtcg
     7021 gcgccgtcgt catcaccatg ggcaaccggc ccgaggaact gcgggcactg ctcgactccg
     7081 tcgcccggca ggacggcgac cccgtcgagg tggtcgtcgt cggcaacggc tcgcccgtcc
     7141 cggacgtccc cgcgggcgtg cggaccgtcg agctgccgga gaacctgggc atccccggcg
     7201 gccgcaacgt cggcatcgag gccttcggac cgggcggcca ggacgtggac gtcctgctct
     7261 tcctcgacga cgacggactc ctcgcccggc aggacaccgc gcagctgtgc cgcgaggcgt
     7321 tcgcggccga cccggagctc ggcatcatca gcttccgcat cgccgacccc gacaccggcg
     7381 tcacccagcg ccggcacgta ccgcggctgc gcgcctccga cccgctgcgc tcctcgcggg
     7441 tcaccacctt cctgggcggc gccaacgccg tccgcacccg ggtcttcgcc gaggtcggcg
     7501 gcctgccgga cgagttcttc tacgcccacg aggagaccga cctggcgtgg cgggccctgg
     7561 acgcgggctg gctgatcgac taccgcgccg acatggtgct ccaccacccg acgaccgcgc
     7621 cctcgcggca cgcggtgtac caccgcatgg tcgcccgcaa ccgggtctgg ctggcccgcc
     7681 gcaacctgcc cgcgctcctg gtccccgtct acctcggggt gtggctgctg ctcaccctgg
     7741 cgcgccgccc ctccggaccg gccttgaagg cctggttcgg cggcttcagg gagggctggg
     7801 ccaccccgtg cggtccccgg cgccccatgc gctggcgtac ggtgtggcgg ctcacccggc
     7861 tgggccggcc cccggtcatc tgacaagctc gaccgtgagg gggacgcgca tggcgcggac
     7921 acgaagacgt aaagacgcac ccgaggacga aagcttccac ccgtgagtga gacaacgcat
     7981 gacggcaggg tcgcggtgac cgcggccccg tcgcccgacg agggactgac ggcggagcgg
     8041 ctcgccgcca ggtacgggct ggccgtgagc ggcgcccggc cctcgctcgc cgagtacgtc
     8101 cgtcagctgt gggggcggcg gcacttcatc ctggccttct cccaggcgaa gctgaccgcg
     8161 cagtacagcc aggccaagct cggccagctg tggcaggtgg cgaccccgct gctgaacgcg
     8221 ggcgtgtact acttcatctt cggcgtcatc ctgcacgcca gccggggcat gtcccaggac
     8281 gtctacatcc cgttcctggt gaccggcgtg ttcgtcttca ccttcacgca gagctcggtc
     8341 atgtcgggcg tccgcgcgat ctccggcaac ctcggcctgg tgcgcgccct gcacttcccg
     8401 cgcgcctcgc tgcccatctc cttctcgctg cagcagctcc agcagctgct gttctcgatg
     8461 atcgtgatgt tcgtcgtggc gatcgggttc ggcagctacc ccggtccgtc ctggctgctg
     8521 atcgtgccgg tgctggtgct gcagttcctg ttcaacaccg ggctcgcgct gatcgtggcc
     8581 cgcatgggag ccaagacccc ggacctcgcc cagctgatgc ctttcatcct gcgtacctgg
     8641 atgtacgcct cgggcgtcat gttctccatc agcaagatga tggagggacg gtccgaactg
     8701 gcggtccggc tgctgcaggt caacccggcc gcggtctaca tggacctgat gcgcttcgcg
     8761 ctgatcgacg gctacggcgc ctcgaacctg ccgccgcacg tgtgggccat cgccctgttc
     8821 tgggccgtgg tcgtcttcgc cggcggcttc gtgtacttct ggaaggcgga ggagcggtac
     8881 ggccgtggct gagcacaccc cccaggtcga agccgaccgg cggccgaccg tcatcgccga
     8941 cgacctgcac atcgtctacc gggtcaacgg cgcccggacc ggcaagggca gcgccacctc
     9001 cgcgctcagc cggatactga ggcgcggcga ggaacgcggc gtgcgcaagg tgcacgccgt
     9061 gcggggcgtg tcgttcgtcg cctaccgcgg cgaggccatc ggcctcatcg ggtccaacgg
     9121 ttccggcaag tccaccctgc tgcgcgccat cgccggcctg ctgcccgccg agaggggcaa
     9181 ggtctacacc gacggccagc cctccctgct cggcgtcaac gcggccctga tgaacgacct
     9241 caccggcgag cgcaacatca tcctcggtgg cctggccatg ggcatgtccc gggaggaggt
     9301 caaggagcgc taccagggca tcgtcgactt ctccggcatc aacgagaagg gcgacttcat
     9361 caccctgccg atgcgcacct actcctccgg catggcggcc cggctgcggt tctccatcgc
     9421 cgccgccaag gaccacgacg tcctcatgat cgacgaggcg ctggccaccg gcgaccgcaa
     9481 gttccagaag cgctccgagg aacgcatccg ggaactgcgc aaggaggccg gcacggtctt
     9541 cctggtgagc cacaacaaca agtccatccg cgacacctgc aaccgcgtcc tgtggctgga
     9601 acgcggtgag ctgcgcatgg acggacccac cgaagaggtc ctcaaggagt acgagaagtt
     9661 caccggcaag tagccggttc gacccagggc cccgccggaa cccgcccggc ggggccccac
     9721 gcttgcaaag gaagcgtcaa ctcgtgctgc ccttaggaat cttgacacca atcggtgtgt
     9781 tgttgtgatg cgcgggacac cccccggtat caggcttggc tgtacaacgt aagctgtacc
     9841 ggtccccgaa agcggcaagt ggggcgataa tgcgcgacac cctccgcagg cggcccgcgg
     9901 agggtcaggc ggcgtgtccg aaatagtgtg tatcggatcg gcagtgtaga acgggagatg
     9961 tgacggcaat ggctacggaa actccccagc tcaacggagc atgtgccgtc cacgcccggg
    10021 gcagcgcgcg gtgacggcac cccgcacggc gccggacctc gaacgcgcca cgctggacaa
    10081 ggccgcgagc gagaacttcc ccgtggcccc cttcttcctg ccccgcgcgt ggcgcgacga
    10141 cctcatggcc gtgtacggct tcgcccggct cgtcgacgac atcggcgacg gcgacctggc
    10201 ccccggcgga gccgacgccc acgccctcgg cgtgtcggcc accgacgccg gcgaccgcct
    10261 ggtcctcctc gacgccttcg agaccgacct gcgccgcgtc ttcgacggca ccccccgcca
    10321 tcccctgctg cgccgcctgc agcccaccgt ccgccgccgc gccctcaccc ccgagccgtt
    10381 cctcggcctg atcgccgcca accgccagga ccagctcgtc acccggtacg agacctacga
    10441 cgacctcctc gcctactgcg agctgtccgc caaccccgtc ggccgcctcg tcctcgccgt
    10501 caccggcacc gcgacccccg agcggatccg cctgtccgac gcgatctgca ccgcgctgca
    10561 gatcgtcgaa cacctccagg acgtcgccga ggacctcggc cgcgaccgga tctaccttcc
    10621 cgccgaggac atgaagcgct tccacgtcca ggaaacggac ctcgccgcga aaatcacggg
    10681 cgcatcgacg cgcgccctgg ttgcatacga agcgcaacgc gcccgcgatc tgctgaatga
    10741 aggcgccccc ctggtgggta gcgtccacgg caggctgaaa ctgctgctcg cggggttcgt
    10801 ggcgggggga agggcggcga tcgacgcgat cgccgccacc gagttcgacg tacttcccgg
    10861 cccgcccaag cccggcaagg tccagttgct gcgtgaggtg ggcgtgaccc tgcgaggaga
    10921 gaggtgatcc ggaccgtgga ttctccgccg cacgtgtccg caccggtact cgccgcctac
    10981 agctactgcg aggccgtcac cgggcagcag gcccgcaact tcgcctacgg catccggctg
    11041 ctgccggcgc ccaagcgccg cgccatgtcg gcgctgtacg cgctttcccg gcgtgtcgac
    11101 gacatcggcg acggcacgct gcccgacgag gtcaagctgg cccgtctgga ggacacccgg
    11161 gcgctgctca cccggatccg ggacggggag gtcgcggagg acgacaccga cccggtggcc
    11221 gtcgccctca cccacgccgc cggcgccttc ccgatcccgc tcggcggcct ggacgagctc
    11281 atcgacggcg tccagatgga cgtgcgcggg gagacctacg agacctggga cgacctgaag
    11341 gtctactgcc gctgcgtggc cggcgccatc ggccgtctct ccctcggcgt gttcggcacc
    11401 gaaccgggcg cgcgcggcgc cgagcgcgca cccgagtacg ccgacacgct cggtctcgcg
    11461 ctgcagctca ccaacatcct ccgggacgtc cgcgaggacg ccgagggcgg ccgcacctac
    11521 ctccccgccg acgacctcgc caagttcggc tgctcggccg ggttccgcgg gccgacgccg
    11581 ccggagggct ccgacttcgc gggcctcgtg cacttcgaag tgcggcgggc ccgcgccctg
    11641 ttcgccgagg gctaccggct gctgcccatg ctcgaccggc gcagcggcgc gtgcgtggcc
    11701 gccatggccg gcatctaccg ccggctgctg gaccgcatcg agcgcgaccc ggaggccgtg
    11761 ctgcgcggcc gggtatcgct ccccggacgc gagaaggcct acgtcgccgt gcgcggcctg
    11821 tccggcctgg acacccggca cgtgtcccgg cacaccgtca ggaggcgcgc ctgatggagt
    11881 ccctggaacg gagcgcccgg gaacgggccg gccgacgccg gcgcatgcgg cgggcaaccc
    11941 tccgccccgg cgtggcgtcc ctgacagcga cggctgagcg tgcaccgtac atccagcacg
    12001 cccggcacgc acggaaggac gcacgatgag cgacgggtca cgccccgccc cggcgcacgc
    12061 cggcaccccg gccgcgcccg gccgcagcgc cgtcgtcgtg ggcgggggac tcgccggcgt
    12121 caccgcggcg ctcgcgctcg ccgacgcggg cgtccacgtc accctgctcg aaggcagacc
    12181 gagactcggc ggcctcgcct tctccttccg gcgcggcgac ctgaccgtcg acaacggcca
    12241 gcacgtgtac ctgcgctgct gcaccgccta ccgctggttc ctcgagcgga tcgggggcac
    12301 ggcgctggca ccgctgcagg accgcctcga cgtgcccgtc gtcgacgccg ccaagcccga
    12361 gggcaggcgg ctcggccggc tgcggcgcga cccgctgccc gtccccctcc acctggggcg
    12421 cagcctggcc gcctatccgc acctctcgct caccgaacgc gccgccgtcg ggcgtgccgc
    12481 gctcgcgctc aaggggctcg acctcaccga tccggccctg gacacgcagg acttcggcag
    12541 ctggctggcc gcccacggcc agtcggcgcg ggccgtcgag gccctgtggg acctggtcgg
    12601 ggtcgccacc ctcaacgcgg tcgcgggcga cgcctcgctg gcgctcgccg cgatggtgtt
    12661 caagaccggt ctgctgtccg acccgggcgc ggccgacatc ggctgggccc gcgtcccgct
    12721 gggcgaactg cacgaccggc tggcccgcaa ggcgctcgac tccgcgggcg tgcgcaccga
    12781 ggtccgtgca cgcgtcacct ccctctccac gaacgacaac gggagctgga acgttcaggt
    12841 tcccggcgag acgctccggg cggacgccgt cgtgctcgcc gtaccgcagc gcgaggccca
    12901 cggcctgctg ccccccggcg ccctcgacgc cccggagcgg ctgctcggga tcggcaccgc
    12961 ccccatcctc aacctgcacg tcgtgtacga ccgcacggtg ctcgcccggc ccttcttcgc
    13021 ggccctcggc acccccgtgc agtgggtgtt cgaccgcacc gacgcctccg gtctgcgcgc
    13081 gggccagtac ctggcggtgt cccagtcggc ggcccgggac gacatcgacg caccggtcgc
    13141 cgtgctgcgc gagcgctacc tgcccgagtt ggagcggctg attccgggca cgcggcgcgc
    13201 cgtggtggag gacttcttcg tgacccggga gcgcacggcg acgttcgccc cggtccccgg
    13261 cgtcgggcgc ctcaggcccg gcgcccgcac cagggttccc ggcctgtacc tggccggagc
    13321 gtggaccgcc accgggtggc ccgcgaccat ggagagtgcg gtccgcagcg gagtgagcgc
    13381 ggccgacgcc gcgctgagcg ccctgggccg gccccgcccc cgccacctct tcgagttcga
    13441 ggaggcggcc tgatgctcga tcagcacagc ccggtgggcc cccgcacccc cggtaccgca
    13501 acaagaggag agactgtgcc cactgtgccc ccggccccga cgcccgctcc ccgggccgcg
    13561 gtggacgtga ccgcgctgct ggagcgcggc cggaccctgg cgacaccggt cctgcgtgcg
    13621 gccgtcgacc gcctggctcc tcccatggac accgtcgccg cgtaccactt cggctggatc
    13681 gacgccgccg gcaacccggc cgacggcgac ggcggcaagg ccgtccgccc ggccctcgcc
    13741 gtcctctccg ccgaggtcac cggcgccgca cccgaggtcg gcgtcccggg cgccgtcgcc
    13801 gtcgaactcg tccacaactt ctccctgctg cacgacgacc tgatggacgg cgacgagcag
    13861 cgccgccacc gcgacaccgt ctggaaggtg cacggccccg cgcaggccat cctggtcggc
    13921 gacgccctgt tcgccctcgc caacgaggtg ctgctggaac tcggcacggt cgaggccggc
    13981 cgcgccaccc gccggctgac caccgccacc cgcgccctga tcgacggtca ggcgcaggac
    14041 atctcctacg agcaccgcga ccgcgtcagc gtcgaggagt gcctggagat ggagggcaac
    14101 aagacgggcg ccctgctcgc cgcctccagc tccatcggcg cggtcctcgg cggcgccgac
    14161 gacgccaccg ccgacgcgct ggagcgctac ggctaccacc tgggcctggc cttccaggcc
    14221 gtcgacgacc tgctcggcat ctggggcgac ccggaggcca ccggcaagca gacctggagc
    14281 gacctgcgcc agcgcaagaa gtccctgccg gtggtcgccg ccctcgcggc gggcggggac
    14341 gcctccgagc ggctcggcga gatcctcgcc gccgacgcca agagcagcga cttcgagaac
    14401 ttctccgagg aggagttcgc ggcccgcgcg gccctcatcg aggaggccgg gggccgcgag
    14461 tggacggccg gggaagcgcg ccgtcagcac accatcgcca tcgaagccct cgacgccgtc
    14521 cgcatgcccg accgggtacg ggccgcgttc acggccctcg ccgacttcgt cgtcgtacga
    14581 aagagatgat cattatcggt cgaatagccc tcgcgtagtc gccggccggt gtcgagggac
    14641 gcggacaccg gccgacggcg gacccacagc agcacgactc gcacgactgc acgaagggga
    14701 agccatgaca gcgacgaccg acggaagcac cggggcgacc ctgccgcccc gcgctgccgc
    14761 ggccagcgac accgccatca ccacccccgc ggcggccggg gcacgccaag ccgccgaaca
    14821 cgcggcacag cgcgccaccg acttcctgct cgcccggcag gacgtcgagg gctggtggaa
    14881 gggcgacctg gagaccaacg tcaccatgga cgccgaggac ctgctgctcc gtcagttcct
    14941 cggcatccag gacgacagca ccacccaggc cgccgccctg ttcatccgcg gcgagcagcg
    15001 cgaggacggc acctgggcca ccttctacgg cggccccggc gaactgtcca ccaccgtcga
    15061 ggcctacgtc gccctccgcc tggccggcga cgcgcccgac gccccgcaca tggcgaaggc
    15121 cgccgcctgg atccgcgaac gcggcggcat cgccgccgcc cgggtcttca cccggatctg
    15181 gctggccctg ttcggctggt ggaagtggga ggacctgccc gaactcccgc ccgagctgat
    15241 ctggttcccc acctggttcc cgctcaacat ctacaacttc gggtgctggg cgcggcagac
    15301 catcgtgccg ctcaccgtcg tctccgccaa gcgcccggtg cgcccggcgc ccttcgcgct
    15361 ggacgagctg cacaccgacc cggcgaaccc caacccgccg cagccgctcg ccccgttggc
    15421 cagctgggac ggcctcttcc agcggctcga caaggttgtc cgcggctacc gcagggtcgc
    15481 cgtgcgcggg ctgcgccggg ccgcgatgaa ctccgccgcc cgctggatca tcgagcggca
    15541 ggagaacgac ggctgctggg gcggcatcca gcccccggcc gtgtactcgg tcatcgccct
    15601 gcacctgctc ggctacgacc tcgagcaccc cgtgatgcgc gagggcctcg cctcgctgga
    15661 ccgtttcgcc gtctggcgcg aggacggcgc ccggatgatc gaggcgtgcc agtccccggt
    15721 gtgggacacc tgcctcgcca ccatcgcgct cgccgacgcc gggctcccgg ccgaccaccc
    15781 gcaactggtc aaggcggccg actggatgct cggcgaggag atcgtccggc ccggcgactg
    15841 ggccgtacgg cggcccggac tgccgccggg cggctgggcg ttcgagttcc acaacgacaa
    15901 ctaccctgac atcgacgaca ccgccgaggt cgccctcgca ctgcgccggg tgcgccacca
    15961 cgacccggag cgcgtggaca aggccatcgg ccggggcgtg cgctggaacc tcggcatgca
    16021 gtcgaagaac ggcgggtggg gcgccttcga cgccgacaac accagcccgt tccccaaccg
    16081 gctgccgttc tgcgacttcg gggaggtcat cgacccgccg tcggcggacg tcaccgcgca
    16141 cgtggtggag atgctcgccg ccgagggcct cgcccacgac ccgcgcaccc ggcgcggcat
    16201 cgcgtggctg ctcgccgaac aggagccgga cggctcgtgg ttcggccgct ggggcgtcaa
    16261 ctacctctac ggcaccgggt cggtggtccc cgcgctcacc gcggccgggc tgcccggctc
    16321 gcaccccgcg atccggcggg cggtgtcctg gctggagggc gtgcagaacg acgacggcgg
    16381 ctggggcgag gacctgcgct cctacaagta cgccggggag tggagcggcc gcggcgcctc
    16441 caccgcctcg cagaccgcgt gggcgctgat ggcgctgctc gcggcggggg agaaggactc
    16501 caaggccgtc gaacgcggca tccagtggct ggccggtacc cagcgggcgg acggctcctg
    16561 ggacgagccg tacttcaccg gcaccggctt cccctgggac ttctccatca actaccacct
    16621 ctaccggcag gtgttcccgc tcaccgccct cggccggtac ctgcacggcg accccttcga
    16681 gcggaacctg ctcgccagga agcccctgcc cgagggcaag gggggctgac cttgagcaaa
    16741 cagcccgccc cggccccgct gctgatcgcc tgcgcgctcg gcatcgagca cctcgccctg
    16801 cgcaccggcg accggagcgg ggcggacggg ccggtcacct tcgtccgtac cggcatgggc
    16861 ccccgggcgg cggaacgctc cctcacccga cacctggccg agccggccct gaccgaggcc
    16921 gccgtcctgg ccaccggctt ctgcgccggc ctcgcccccg gcatgcaccc cggcgacctg
    16981 gtcgtcgccg aggagacccg cgacccgcgc ggttcggtcg cctgtctggg caccgagctg
    17041 ctggtgaagg aactcgtgcg catcctgccc gggcgcacgg tccacaccgg cccgctcacc
    17101 ggctccgacc acgtcgtgcg cggcaccgag cggtccgacc tgcgcgccac cggcgcgatc
    17161 gcggtcgaca tggagtcggc ggccacgctg ctcagcgccg tacgggcggg tgagcgcccg
    17221 gtggcggccg tccgggtggt cgtggacaca cccgaacacg aactcgtccg gatcggcacg
    17281 gtgcgcggcg gaatatcggc tcttcgcgta ctccgccgcg tcctccccgc atttttcgaa
    17341 tggcaccgtt ctttgctgct cccccggagg tgagccagat ggccatgccg ttgcgtcagt
    17401 ccatcaaggt cgctacatac ctggccgaac agaagctccg caggcgggac aagttcccgc
    17461 tcatcgtgga gctggaaccc ctgttcgcct gcaacctcaa gtgcgaggga tgcggcaaga
    17521 tccagcaccc ggccggggtg ctcaagcagc gcatgccggt cgcccaggcc gtcggcgcgg
    17581 tgctggagtc cggcgcgccg atggtgtcca tcgccggcgg cgaaccgctg atgcacccgc
    17641 agatcgacga gatcgtgcgg cagttggtgg cgaagcgcaa atacgtcttc ctgtgcacca
    17701 acgccatgct gctgcgcaag aagatcgaca agttcacgcc ctctccctac ttcgccttcg
    17761 cggtgcacat cgacgggctg cgcgagcggc acgacgagtc cgtggcgaag gagggcgtgt
    17821 tcgacgaggc cgtggaggcc atcaaggagg ccaagcggcg cggcttccgg gtgaccacca
    17881 actcgacctt cttcaacacc gacaccccgc agaccgtcgt cgaggtgctc aacttcctca
    17941 acgacgacct ccaggtcgac gagatgatga tctcgcccgc ctacgcctac gagaaggccc
    18001 ccgaccagga gcacttcctc ggtgtcgagc agacccgcga actgttccgc aaggccttct
    18061 cgggcggcaa ccggggccgc tggcggctca accactcccc gctcttcctg gacttcctgg
    18121 agggcaaggt cgacttcccg tgcaccgcgt gggccatccc gaactactcg ctcttcggct
    18181 ggcagcgccc ctgctacctg atgagcgacg ggtacgtgcc gacgtaccgc gaactcgtcg
    18241 aggacaccga ctgggacaag tacggccgcg gcaaggaccc gcgctgcgcc aactgcatgg
    18301 cccactgcgg ctacgagccc accgccgtcc tcgccaccat gggctcgctg aaggagtcgc
    18361 tgcgggccat gcgcgagacc gtctccggaa accgggagtg aggccatgac cgcggtttcc
    18421 ctgggcgttc ccgaggtgcc ggcccggccg gtcgcgccgc ggcgcgtgtc gcgcc
//
