LOCUS       NZ_KQ948858            20996 bp    DNA     linear   CON 21-APR-2024
DEFINITION  Streptomyces bungoensis strain DSM 41781 PRJNA299233_s008, whole
            genome shotgun sequence.
ACCESSION   NZ_KQ948858
VERSION     NZ_KQ948858.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces bungoensis
  ORGANISM  Streptomyces bungoensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 318751)
  AUTHORS   Ruckert,C., Winkler,A., Kalinowski,J., Kampfer,P. and Glaeser,S.
  TITLE     Draft genome sequence of Streptomyces bungoensis DSM 41781, type
            strain for the species Streptomyces bungoensis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 318751)
  AUTHORS   Ruckert,C., Winkler,A., Kalinowski,J., Kampfer,P. and Glaeser,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-OCT-2015) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 13-OCT-2014
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 60.6x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001514215.1-RS_2024_04_21
            Annotation Date                   :: 04/21/2024 02:15:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,539
            CDSs (total)                      :: 7,454
            Genes (coding)                    :: 7,226
            CDSs (with protein)               :: 7,226
            Genes (RNA)                       :: 85
            rRNAs                             :: 1, 1 (5S, 16S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            tRNAs                             :: 80
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 237
            CDSs (without protein)            :: 228
            Pseudo Genes (ambiguous residues) :: 0 of 237
            Pseudo Genes (frameshifted)       :: 67 of 237
            Pseudo Genes (incomplete)         :: 196 of 237
            Pseudo Genes (internal stop)      :: 10 of 237
            Pseudo Genes (multiple problems)  :: 43 of 237
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:26:42
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 184053
            Orig. end                         :: 205049
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KQ948858.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20996
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20996
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20996
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10996](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10996
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(496..510)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.46"
                     /tool="antismash"
     misc_feature    980..994
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     gene            complement(2223..3077)
                     /locus_tag="AQJ66_RS18525"
                     /old_locus_tag="AQJ66_18530"
     CDS             complement(2223..3077)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013718.4"
                     /locus_tag="AQJ66_RS18525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_18530"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_061922975.1"
                     /transl_table=11
                     /translation="MNALRRIRWQYAVIALLAVAAAAFGLLRPASAPAAAASKKKLSAT
                     DRIKQNPPPALFTDADVAAIGKQAAAQRAKADALFAQWKKAHGTARDDKAFVAWAARQV
                     PAPPTAAERTAELRQDQKLARTRTAAGKKAATWLELNGKKDIWKLYLHDQRELLPKTQG
                     TADKAQLKAALKLAKTVSDQVAARDKQPAPFVLDPSLRPEKHIKPGAKGPYSYPSRHAT
                     RSAAAVTFLSALFPHRAEDYRWMQAEVLYSRLYMAGHVSSDLTAGTLLGDLIGDYELTV
                     GGH"
     gene            complement(3074..3892)
                     /locus_tag="AQJ66_RS18530"
                     /old_locus_tag="AQJ66_18535"
     CDS             complement(3074..3892)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607124.1"
                     /locus_tag="AQJ66_RS18530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_18535"
                     /product="VTC domain-containing protein"
                     /protein_id="WP_061922978.1"
                     /transl_table=11
                     /translation="MKPASPLAADLGLAGLRGATLAEVDAAAALQHRTDRKYLLPLDRA
                     RLLVDGLADTHHVLDLGGRRTTSYLSTYFDTERLGAWRAHVQRRRRRWKVRTRLYAEDA
                     LCRVEVKTKDGRGATVKHALKAPAHAYGRLDDTAAGFVDDVLRRADVAVTAASLSPAAE
                     IRYVRAALADLGHGTRVTLDGLLTCHRGDRTAALDPGHVLVETKGGARPAPADRLLLRL
                     GARPVSLSKYIVGQSLLTPGLPDNDVRRLARTHFTATARPAPLLERTPAA"
     gene            complement(3892..4542)
                     /locus_tag="AQJ66_RS18535"
                     /old_locus_tag="AQJ66_18540"
     CDS             complement(3892..4542)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607125.1"
                     /locus_tag="AQJ66_RS18535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_18540"
                     /product="DUF4956 domain-containing protein"
                     /protein_id="WP_061922981.1"
                     /transl_table=11
                     /translation="MDALVLAAKGITQHIAPTDLTTRGGIDVVALLILVGWLYRRRPSA
                     PAMPLVLVALNVGLFAAMSTISAGRFPAGVGFGLFGILSLVRLRSAAFTLRDVAYTFVA
                     LVMALCTGLPQRDSWLVIALDAVVLVAVLLVDDSRAYRPPTRTVKLTLDRVYDDPSLIA
                     QDVAFRFGQAPVSVEVDEVDYVRETTRVSARYPALPDEPAPAGDGAPREQVTA"
     gene            4704..5375
                     /locus_tag="AQJ66_RS18540"
                     /old_locus_tag="AQJ66_18545"
     CDS             4704..5375
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607126.1"
                     /locus_tag="AQJ66_RS18540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_18545"
                     /product="response regulator transcription factor"
                     /protein_id="WP_061922984.1"
                     /transl_table=11
                     /translation="MHYLVVDDETRLTDLVVRYLTESGHTAEGRYDGPTGLAAARDPRL
                     DGIVLDVMLPGLGGVEVCRTLRGEGVDVPVILLTARGAISERVAGLDAGADDYLVKPFA
                     MEELLARLRAISRRRPDSTGRLQVGDLVLDPAQQRAWRAGTELDLSRREFAVLRVLMEN
                     AGRVVSRLQLLDEVWDGETDLRSNAIDVHVSKVRAKVDRAFGRTTITTLRGRGYRLEII
                     P"
     gene            5372..6745
                     /locus_tag="AQJ66_RS18545"
                     /old_locus_tag="AQJ66_18550"
     CDS             5372..6745
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="AQJ66_RS18545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_18550"
                     /product="ATP-binding protein"
                     /protein_id="WP_061922986.1"
                     /transl_table=11
                     /translation="MSTLARPPAWFGRLPVVTRLVLAVAVTMSLVLTGTAGLVYWRVQA
                     ALDRQLHDDLTAYQHGLDRAVRAGTALPPGPSGSHYQVLDTRGRVLKSSHAVRHRALLT
                     AAEVRSAARGHAVRRDIGSLLPITPDTLRLQARRVRTGGRTRIVVAAVQRGHRDEALRE
                     LLAQLAIASGLTLVAASYVGYRTARAALRPVERYRSGAATLADGTHHLRLDVPTDRDDE
                     ITRLGHTLNRMLDRLEASAARERRFVADASHELRTPLSLLRAEVDVALHRPRSAGELTE
                     TLRSVDAEVQRLIDLSNALLDLEELGGTGHITRAPVRLADLVGTAVAPHVRTAERAGRA
                     LAVDAADTAVAVDARWLVPALGNLVDNALRHGRGTVRLTAAVREGRLRLDVTDEGPGFP
                     PEFLPRAFDRFARAEASRTGEGSGLGLAFVQAVATAHGGTVRAENTGRGTEVALDLPY"
     gene            complement(6876..7754)
                     /locus_tag="AQJ66_RS18550"
                     /old_locus_tag="AQJ66_18555"
     CDS             complement(6876..7754)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607053.1"
                     /locus_tag="AQJ66_RS18550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_18555"
                     /product="hypothetical protein"
                     /protein_id="WP_061922989.1"
                     /transl_table=11
                     /translation="MDDSELLTDREAAGTGTYVMKKLPEVTLAFWIMKIAATTLGETAG
                     DLFSQTMGLGYFLTTIALFLVFVVTLVVQLASRRYNPFFYWTVILSTSMAGTTMSDFMN
                     RDASAEYLSGGATSLGRGPQGLGLGYPAGAAILVSVLVVIFTVWKLSGMTFVIRDITTF
                     RGEALFWSAILVSNTLGTSMGDFLSDSSGLGYLGGALLVSGLLVVLLLLTRVPAVPNVL
                     LFWIAFVLTRPLGATAGDFLTKPVAKGGLDLGTAGSSAVLLLVLLGLMGHAHLKERRNA
                     VPGAEAVARSS"
     gene            8180..9841
                     /locus_tag="AQJ66_RS18555"
                     /old_locus_tag="AQJ66_18560"
     CDS             8180..9841
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF018884.4"
                     /locus_tag="AQJ66_RS18555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_18560"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_159052581.1"
                     /transl_table=11
                     /translation="MRTAAFRGDESRPGAFQASASIVQAGFFCWEIATGEISCDPLTLA
                     LHGMPEHGPSDITDFLAAVHESDLADVRDALGLIAKSCGNYQIEYRVTSGDGRHRSLEA
                     RGRVLPGADGQPARMVGVVMDTTAVHERHEAERRRFHERATRDRWMRELTAALAAAVTV
                     RDIMAAAQAGLRAFGADALAVIAPEGSRLTVVASCADDEQGEASPRALDATARTLVEES
                     LERRAPVLVGSADALVTDRPHLAPLARPAPQAWAALPLTDSRGRASSCLVSFPEPQEFL
                     PEERALLVAAVGLLAQSLERAGMYESEHALATELQRGMLPRGPLTVPGVTIAARYQAAT
                     SGMWIGGDWYDAISLPDGGVALVIGDVQGHSVHAASLMGRLRTAVHAYANEGHPPAAVL
                     ERTNRLLTELNTDPDRALFATCCYIALNPADGTLRVCRAGHPAPALITPRRPPRLLEVP
                     GGLPLGIDREQRYPTTRLRVAPGSVLALTTDGLLEAVDKDIDQGTERFLRGLRGAPTAD
                     LETVVDGLLAGTRRPHGPGDDVAVLLARLNRPGRRG"
     misc_feature    9954..9969
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.47"
                     /tool="antismash"
     gene            10001..10996
                     /locus_tag="AQJ66_RS18560"
                     /old_locus_tag="AQJ66_18565"
     CDS             10001..10996
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="AQJ66_RS18560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_18565"
                     /product="hypothetical protein"
                     /protein_id="WP_061922997.1"
                     /sec_met_domain="T1TS (E-value: 6.6e-67, bitscore: 220.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTFRIPDLCIPVPAALNPELRTATAATDAWLDEFGLVPTEEARR
                     HVQRTRVDRLTAWLCPNASAEALTLITQWNAWLFQLDDQFDDDPVRGYQPERWREAFGP
                     LFAVFDGTVAAGRLARSLADLWRRTTAVRSSAWQRRFVPHLLWYFDSYRADMIHREEGR
                     VPGLQQYLAHRRASFAFDAVLDLMEIGTGVDLPDRLHANPAFADMREAVIYANACVNDL
                     YSLRKELAHDYAFNAVTVIGHHHRCDLQEAVDRVAAMQAGYVQRILDLEQVLPERLTRA
                     GLADDVADDALRCVRDFHALTAGNVAWSKETGRYAEIEAQPTYLADLFIP"
     gene            11264..11953
                     /locus_tag="AQJ66_RS18565"
                     /old_locus_tag="AQJ66_18570"
     CDS             11264..11953
                     /NRPS_PKS="Domain: Abhydrolase_1 (37-145). E-value:
                     2.1e-12. Score: 39.1. Matches aSDomain:
                     nrpspksdomains_AQJ66_RS18565_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005318295.1"
                     /locus_tag="AQJ66_RS18565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_18570"
                     /product="triacylglycerol lipase"
                     /protein_id="WP_244162856.1"
                     /sec_met_domain="PF00561 (E-value: 4.2e-11, bitscore: 37.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTLMSAAAAAAGALLAVQASLPAHAASGSTFGSTSNPVLFVHG
                     YTGAGSNWDTMASRFKTDGWPSSYLDQWSYDWRQSNATTAQQLSTEVDRLLAATGATKV
                     DIVSHSMGGLSSRYYLKNLGGDSKVDAWVSLGGPNHGTDSANTCFDTSCTEMRIGSSFL
                     TALNSGDETPGTPRYATWWSPCDTVINPDSSVSLSGAANTQTSCLSHTGLLTDATVYAQ
                     TRNMINS"
     aSDomain        11375..11698
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AQJ66_RS18565_Abhydrolase_1.1"
                     /evalue="2.10E-12"
                     /label="AQJ66_RS18565_Abhydrolase_1.1"
                     /locus_tag="AQJ66_RS18565"
                     /protein_end="145"
                     /protein_start="37"
                     /score="39.1"
                     /tool="antismash"
                     /translation="NPVLFVHGYTGAGSNWDTMASRFKTDGWPSSYLDQWSYDWRQSNA
                     TTAQQLSTEVDRLLAATGATKVDIVSHSMGGLSSRYYLKNLGGDSKVDAWVSLGGPNHG
                     TDSA"
     gene            12325..13824
                     /locus_tag="AQJ66_RS37370"
     CDS             12325..13824
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432037.1"
                     /locus_tag="AQJ66_RS37370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_244162858.1"
                     /transl_table=11
                     /translation="MTLNAPSAAPTDVSNDRERTGSPASTGRPSPAPFDAISFVFAQRP
                     STGRLVGIDLARGLAVFGMYSAHVGPDVTVGGPMGFLLEAARGRCSALFALLAGFSLII
                     ITGRPCPRTGRAGRQAVARVVIRAVVLAVLGYALTALDTDVAVILSFYGLLFLAVLPLH
                     RLRAGALALVAAAGALVMPPLLYVIRNSIEQGHWADAVIARDPLARITGTDGFVELLFT
                     GEYPVLTWMPFLVAGMAVARLDLTRPGTRSRLALAGGGLALLGYGGSWLALRLVPHALS
                     TVAAATDGGSASSAWWSDTVGDPVNHTPLDWLLVAAPHSQTTFSVLGNTGVALAVVAGC
                     LTVADRMPRLMRLAGPVAAVGTMALTVYVLHIVALWFLTDAWRVPAIEDGSLNALPVLL
                     GFILAATILAMVWTSTFRRGPLEYLLHQATRPARCVGPRATRASSPGRAEHLVGAARLR
                     ARLLVQLVARDGGPPVDLLAGPHDVAEGSVLGGDPPGREGQ"
     gene            complement(14840..16192)
                     /locus_tag="AQJ66_RS18575"
                     /old_locus_tag="AQJ66_18580"
     CDS             complement(14840..16192)
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670205.1"
                     /locus_tag="AQJ66_RS18575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_18580"
                     /product="Dyp-type peroxidase"
                     /protein_id="WP_061923003.1"
                     /transl_table=11
                     /translation="MNTADSGGSAGVRVEIEDVQSGALRPRPVPYEGKFVFLRVDDRHA
                     GRALLRRLLPVTSGGLPSADLSRDAWVAVAFTHQGLRALGVPQDSLDSFPRAFREGMAA
                     RAERIGDVGANAPAHWEAPFGSGDVHIALSALSSDTAQLDEELERARAAYEDTPGVRVI
                     WQQDVHQLPTGRTTFGFRDGISHPNIEGVGLPGSNPQEAPIKAGEFILGYPDETGNLPP
                     MPRPDVLGRNGTYVAVRKIHTDVAAWRRYLRANSSSAEEEALLAAKMVGRWPSGAPLTL
                     APEHDDPELAADPQRVNNFLYREHDDRGLRCPAGAHIRRNNPRDATIVGDARMHRLIRR
                     GTTYGPPLPEGVLEDDGADRGLVGVFIGAHLERQFEFIKAEWVNDGNFIGYPGEKDPVA
                     GHHDGTGSVTIPGKPVRRRLRNLPSFVVTRGGEYCFVPGLRALRWLAEMED"
     gene            complement(16325..16915)
                     /locus_tag="AQJ66_RS18580"
                     /old_locus_tag="AQJ66_18585"
     CDS             complement(16325..16915)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016573652.1"
                     /locus_tag="AQJ66_RS18580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_18585"
                     /product="hypothetical protein"
                     /protein_id="WP_244162859.1"
                     /transl_table=11
                     /translation="MTATAQPSRSAHPERPGRSDGVCSEFTVFTEIKPGHADALREVLA
                     TLADAADDERVHAAVRQIGTLHDARHVIFDNDTRFMFASVFDGSWDAYIDDFAKTVVGE
                     RFDKVFSHSEGFPGISDPGVKDWFVAHQAPAGVFVSAYPDLTVQQIYKDHRVEEAFEEV
                     LDTPEFRAALENPANAELVATPAFQKLLEEASA"
     gene            17313..17990
                     /locus_tag="AQJ66_RS18585"
                     /old_locus_tag="AQJ66_18590"
     CDS             17313..17990
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014673658.1"
                     /locus_tag="AQJ66_RS18585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_18590"
                     /product="GAP family protein"
                     /protein_id="WP_061923009.1"
                     /transl_table=11
                     /translation="MGAVLGDVLGFAAAVAVSPLPIIAVILILATPRGPLNGVLFTLGW
                     ILGLSALGAVMLAIASPASASANSHPATWVGALKLALGLFLVLFGARKWHRRPKDPSQA
                     QLPKWMSAIDRLTPVKIFALGLALAALNAKNAPLTIAAGATIGSAGLPVAQQVASLAVF
                     VLIATLGLLAPLGVFLLGGERARATLGNWKDWAAQHNVAVMAVLFFVLGLKLLGDGISV
                     LVS"
     gene            complement(18005..18442)
                     /locus_tag="AQJ66_RS18590"
                     /old_locus_tag="AQJ66_18595"
     CDS             complement(18005..18442)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018889633.1"
                     /locus_tag="AQJ66_RS18590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_18595"
                     /product="ATP-binding protein"
                     /protein_id="WP_061923012.1"
                     /transl_table=11
                     /translation="MLAPLRPLDAPRGRASAWDASWPLPRELTSVRQARHLVTRQLGDW
                     SVDDLADAVELLVSEVVTNALRHTRGPLRLNLRLCGSCLLCEVEDTESAGPVRNVVDAD
                     AEGGRGTELLDLLADAWGSSRTATGKTVWFEVRHTGLPHVR"
     misc_feature    18646..18666
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 23.88"
                     /tool="antismash"
     gene            18737..19336
                     /locus_tag="AQJ66_RS18595"
                     /old_locus_tag="AQJ66_18600"
     CDS             18737..19336
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557942.1"
                     /locus_tag="AQJ66_RS18595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQJ66_18600"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_061923015.1"
                     /transl_table=11
                     /translation="MPRPPDPAKRRDLLDRIRAYVLRNGLSDLSLRPLARALGTSDRML
                     LYYFGTKERMVAEALAVYERRPLLRARELLETVGPPTDPAGLRRFMEEVWRQFRASDVR
                     ASLPLYLEIMSAGVLHPDRYGPVMRDIVTGWTELLASVFRELGMTRDGARTQATVLADA
                     ALGLLIAPLADGHWDRADTAFRTLLDALEPGWHARE"
     misc_feature    19229..19231
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(19388..19403)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.71"
                     /tool="antismash"
     misc_feature    20853..20866
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.6"
                     /tool="antismash"
ORIGIN
        1 tcgcacagtt cgtccagggg ccgtccgccg tccgcgagga ctccggccag ctgcgcgaga
       61 ccgtcgtcgc ggccgtcggc cgcctgcagc aggccgcccg tgaagagcac gacgacgctg
      121 cccggcgcca gctccagctc cgtgctctgg tagggcgggc cgccgacgcc cagcggcggt
      181 ccgggcggca gccgcgggaa gcggacggcg cccgtgtccg gttccaccac cgccggcacc
      241 gagtcccccg cccgcgccag gctgcacctg ccggagacgg ggtcgtacac cgcgtacagg
      301 caggtcaccc cctcggcctc gtccgagcgg cgcgccggac ggcccgggtc gcggccgtcc
      361 tcgtgctgct cgtacgccgt ctgctcgacc aggtcgccca ggcgggacag cagttcgtcc
      421 ggggtcaggt ccagccgggc gaggacgcgc acccccgtgc gcaggcggcc catggtggcc
      481 gcggcgcgca ggccgtggcc gaccacgtcc ccgacgacca ggccgacgcg ggtgcccgac
      541 agcgggatga cgtcgtacca gtcgccgccg acccccgacc cgctgtcggc gggcaggtag
      601 cggctcgccg tgtcgagggc ggtgtgcggc ggcaggtggg acggcagcag gctccgctgg
      661 agcttgaggg tcacgctgtg gccccgtgtg accaggggca tcagcagcag gccgagcagc
      721 agggcgccga gccccacggc ggtgaccccg ccggtcggcc ccaccagcgg caggttcacg
      781 ctggtcgcgc cgtacccggg atcggcgtag acgaaagtgg cgtacacgaa caggcaggcc
      841 atgaccagcc cgcccagacc gggcagcacg cccttgaaga ccaggtcccg gatgctgcgg
      901 gtgaggaccc cgcggtggta ccagaggcag gcgaacccgg tcagggcgta ctggaacgtg
      961 atggcgaggc cgaccgagtc gatcgagtcg gccagcacgt tcccgctgaa cgaggacagc
     1021 aggaccagga agccgatcga gaccgcgccc atgccgacgg tcgaccaggt cggcgtcagg
     1081 aacctgcggt gcacccgcgc gaaccgggcc ggcagggcct tgtggaccgc catggagaac
     1141 acggtccggg acagcggcag gatggtggtc tgggtggagg cgagcgccga ggtcagcacc
     1201 atgaggatca gcagtctcgt cagcaccagg cccacgtcgc tgcccccgaa gacggcgctg
     1261 cccagccccg agagcacatc gtccgagttg ccggggtcgc ccaggccgac gcccgaggag
     1321 ccgaccccgg cgaaggcctg cgccgcggtg gtcaccagcc cgtacatgac caggagcagc
     1381 acggtcgaca ggatggcggc gcgcccgggg atgcgggtgc tgtcgacggt ctcctcgttg
     1441 atcgagacca cggtgtccca gccccagtag atgaagacgc ccgccaggac ccccgaggtc
     1501 agggccctgg aggaggacac ctcgaagggg ttgaaccagg aggcggagac gtggatcgcc
     1561 gtcgggggcg ggtcggtgta gaccctggtc agcgcggcga cggcgaagac gagcagcatg
     1621 cccgcctcca ggcacagcag ccagcgctgg acggcggccg agaactcgat gccgacgtag
     1681 cagaccgtcg tcatcacggc gatccagacg acgccggcca cggtggtcca cagccggtcg
     1741 tcggccagcg cgtccaggcc caccaggcgg aagctgtacg acccggcgat ctcggcgagg
     1801 ctcgccatga cgatgacgtc ggcgacgacg atgccccagc cgcccatcca gccggtccgc
     1861 gggccgaagg cgcgcgtcgc ccaggtgtag gtggtgccgc agtcggcgtc gctggcgttc
     1921 agctcccgga aggcgtacgc gaccagcagc atcggcagga acgacagcat gacgacgatc
     1981 ggggactgca gcccgacggc caccacgatc agcccgagcg tcgcggcgag gctgtaggcc
     2041 ggggcggtgg acgcgacccc gatgaccacc gacgacagca ggcccagggc atcgctcttg
     2101 agccccttgc ggccggcccc cgttcccgga gcgggacgac cggcaaaccc ggcgccacca
     2161 aagtgcctca cacttgattg caacgccgcg ccggtccccc gcgcaaccgc gcccgggccg
     2221 ggtcagtggc cgccgaccgt gagttcgtag tcgccgatca ggtcgccgag cagggttccg
     2281 gcggtgaggt cactggagac gtgaccggcc atgtacagcc gcgagtagag cacttccgcc
     2341 tgcatccacc ggtagtcctc ggcccggtgc gggaagaggg cgctgaggaa ggtgacggcc
     2401 gcggcggacc gggtggcgtg ccgggagggg taggagtagg ggcccttggc tccgggcttg
     2461 atgtgcttct ccggacgcag ggaggggtcc aggacgaacg gcgccggctg cttgtcacgg
     2521 gcggcgacct ggtcgctgac ggtcttcgcc agcttcaggg ccgccttgag ctgggccttg
     2581 tccgccgtgc cctgcgtctt gggcaggagt tcgcgctggt cgtggaggta cagcttccag
     2641 atgtccttct tgccgttgag ctccagccag gtggccgcct tcttcccggc ggccgtgcgg
     2701 gtcctggcga gcttctggtc ctgccggagt tcggcggtgc gctccgcggc ggtgggcggc
     2761 gccgggacct ggcgggccgc ccaggcgacg aacgccttgt cgtcgcgggc ggtgccgtgc
     2821 gccttcttcc actgggcgaa gagggcgtcg gccttggcgc gctgggcggc ggcctgcttg
     2881 ccgatcgccg cgacgtcggc gtccgtgaag agggccgggg gcgggttctg cttgatgcgg
     2941 tcggtcgccg acagcttctt cttcgaggcg gcggccgcgg gggccgaagc cggccgcagc
     3001 aggccgaacg cggcggccgc cacggcgagc agggcgatga cggcgtactg ccatctgatg
     3061 cggcgcaggg cgttcatgcg gcaggagtcc tttcgaggag cggtgcggga cgtgccgttg
     3121 cggtgaagtg ggtacgggcg agacggcgta cgtcgttgtc gggcaggccc ggggtgagca
     3181 gggactggcc gacgatgtac ttggagaggg agacgggccg ggcacccagg cgcagcagca
     3241 gccggtcggc cggggccggc cgggcgccgc ccttggtctc gacgaggacg tgccccgggt
     3301 cgagcgcggc ggtgcggtcc ccccggtggc aggtgaggag gccgtcgagg gtgacgcgcg
     3361 ttccgtggcc gaggtcggcg agggccgcgc ggacgtagcg gatctccgcc gccggggaga
     3421 gcgacgcggc ggtgacggcg acgtccgccc ggcgcagcac gtcgtcgacg aacccggcgg
     3481 ccgtgtcgtc gagccggccg taggcgtggg ccggtgcctt gagggcgtgt ttgacggtgg
     3541 cgccgcggcc gtccttcgtc ttcacctcca cccggcacag cgcgtcctcg gcgtacaggc
     3601 gggtgcggac cttccagcgc cggcggcggc gctggacgtg ggcccgccag gcgccgagcc
     3661 gctcggtgtc gaagtaggtg ctgaggtagc tcgtcgtacg gcgtccgccg aggtcgagga
     3721 cgtggtgggt gtcggcgagc ccgtccacga ggaggcgtgc ccggtccagg ggcagcaggt
     3781 acttgcggtc ggtgcggtgc tggagcgcgg ccgccgcgtc cacctcggcg agcgtggcgc
     3841 cgcgcagccc ggccagcccg aggtccgccg cgagggggga ggcgggcttc atcaggcggt
     3901 cacctgttcg cgcggcgcgc cgtccccggc gggggcgggc tcgtccggca gggccgggta
     3961 gcgggcggag acccgggtgg tctcgcggac gtagtcgacc tcgtcgacct cgaccgacac
     4021 cggggcctgc ccgaagcgga aggcgacgtc ctgggctatc agggacggat cgtcgtagac
     4081 gcggtccagg gtcagcttca ccgtgcgggt cggcggccgg taggcgcggg agtcgtcgac
     4141 cagcaggacc gccaccagga cgaccgcgtc cagcgcgatg acgagccagc tgtcgcgctg
     4201 cgggagcccg gtgcacaggg ccatgaccag ggccacgaag gtgtaggcga cgtcgcgcag
     4261 ggtgaacgcc gcgctgcgca gccggaccag ggagaggatg ccgaagaggc cgaagccgac
     4321 cccggccggg aacctgcccg cgctgatcgt gctcatcgcc gcgaacagac cgacgttcag
     4381 cgcgaccagg accagcggca tcgcgggtgc gctgggccgg cgccggtaca gccagccgac
     4441 caggatcagc agggcgacga cgtcgatgcc gccgcgtgtg gtgaggtccg tgggtgcgat
     4501 gtgctgggtg atgcccttgg cggcgagcac cagtgcgtcc atgactgtga ccgtcccttc
     4561 cgtcccggca cgtcggacgg cggaccggcc gcggtccgcg gtggggccgc gacttcgaag
     4621 gacggtaggg atgtcacatg aacagaccat gaagcttttc ggtcgtgtcc gggcgcgttc
     4681 ggcaggccgt tagcctggcc ggtatgcact acctggtcgt cgacgacgag acccgcctca
     4741 ccgacctcgt cgtccgctac ctcaccgagt ccggacacac cgccgaaggc cgttacgacg
     4801 gccccaccgg cctggccgcc gcccgcgacc cccgcctgga cgggatcgtc ctggacgtga
     4861 tgctgccggg gctgggcggc gtcgaggtgt gccggacgct gcgcggcgag ggcgtcgacg
     4921 tccccgtgat cctgctcacc gcgcgcggcg cgatcagcga acgcgtcgcc ggactggacg
     4981 ccggcgccga cgactacctg gtcaagccgt tcgccatgga ggaactgctg gcccggctgc
     5041 gcgcgatatc ccggcgccgg cccgacagca ccggccgcct ccaggtcggc gacctcgtcc
     5101 tcgatcccgc gcagcaacgg gcctggcggg cgggcacgga gctcgacctg tcccggcggg
     5161 agttcgccgt gctgcgggtg ctgatggaga acgccggccg cgtggtgtcc cggctccagc
     5221 tgctggacga ggtctgggac ggcgagacgg acctgcgcag caacgccata gacgtccacg
     5281 tctccaaggt gcgcgccaag gtcgaccgcg ccttcggccg cacgacgatc acgaccctgc
     5341 gcggacgcgg ctaccgcctg gagatcatcc cgtgagcacg ctggcccggc cgccggcctg
     5401 gttcgggcgg ctgccggtcg tcacccgtct cgtgctggcc gtcgccgtca ccatgtcact
     5461 ggtgctgacc gggacggccg ggctggtcta ctggcgggtc caggccgccc tcgaccggca
     5521 gctgcacgac gacctgaccg cctaccagca tggcctggac cgggccgtcc gcgccggcac
     5581 cgcccttccg ccgggcccga gcggcagcca ctaccaggtc ctcgacaccc ggggccgtgt
     5641 cctgaagtcc agccacgccg tacgccaccg ggccctgctc accgccgcgg aagtccgctc
     5701 cgccgcacgc gggcacgccg tccggcggga catcggctcc ctgctgccga tcaccccgga
     5761 cacgctgcgc ctccaggcca ggcgcgtccg gaccggggga cgcacgcgca tcgtcgtggc
     5821 ggccgtgcag cgcgggcacc gcgacgaggc gctgcgggaa ctcctcgccc agctggcgat
     5881 cgcctccggc ctcacgctgg tcgccgcctc ctacgtcggc taccgcaccg cccgcgccgc
     5941 cctgcgcccg gtcgagcgct accgcagcgg cgcggccacc ctcgcggacg gcacccacca
     6001 cctgcgcctg gacgtgccca ccgaccgcga cgacgagatc acccggctcg gccacaccct
     6061 caaccgcatg ctcgaccgcc tggaggcctc cgcggcccgc gagcgccggt tcgtcgcgga
     6121 cgccagccac gaactgcgca cccccctgtc gctgctgcgg gcggaggtgg acgtggcgct
     6181 gcaccgcccc cgctcggccg gggagctcac cgagaccctg cgctccgtgg acgccgaggt
     6241 gcagcggctg atcgacctgt ccaacgccct gctggacctg gaggaactcg gcggcaccgg
     6301 ccacatcacc cgggcgccgg tccggctcgc cgacctcgtc ggcaccgcgg tggccccgca
     6361 cgtgcgcacc gcggaacggg ccggacgcgc cctggccgtc gacgcggcgg acaccgcggt
     6421 cgccgtcgac gcccggtggc tggtgcccgc cctcggcaac ctggtcgaca acgcgctgcg
     6481 ccacggccgg ggcaccgtcc gcctcacggc cgccgtccgg gagggccgac tgcggctgga
     6541 cgtcaccgac gagggtcccg gcttcccgcc ggagttcctg ccccgcgcgt tcgaccgctt
     6601 cgcccgtgcc gaggcgagcc gtaccggcga gggttcgggg ctgggcctcg ccttcgtcca
     6661 ggcggtggcc accgcccacg gcggcacggt ccgcgccgag aacaccggcc ggggcacgga
     6721 ggtcgccctc gacctgccgt actaggtcct gtccggacgt actcgggtcg gcgcccggtg
     6781 cggcgagtgg gggcacctcc cacgcccttc aggcagtggg ggagcgtgca tggcgtcgtg
     6841 gggcaggcgg gagttcgacg acagggcctg ggtccctagc tgctgcgggc caccgcctcg
     6901 gctcccggga cggcgttcct gcgctccttc aggtgggcgt ggcccatgag gccgaggagg
     6961 accagcagga gcacggcgga cgagcccgcc gtaccgaggt ccagaccgcc cttggcgacg
     7021 ggcttggtga ggaagtcacc cgcggtggcg ccgagcgggc gggtgagcac gaaggcgatc
     7081 cagaacagca ggacgttggg gacggccggg acccgcgtga gcagcaggag caccaccagc
     7141 agtcccgaga ccaggagcgc gccgcccagg tagccgagcc cggagctgtc ggacaggaag
     7201 tcccccatgg acgtgccgag cgtgttggag acgaggatcg ccgaccagaa gagggcctcg
     7261 ccgcggaacg tggtgatgtc ccggatgacg aacgtcatcc cgctgagctt ccagacggtg
     7321 aagatgacga cgaggaccga gaccaggatc gcggcgccgg ccgggtagcc cagtcccagg
     7381 ccctggggac cccggcccag cgaggtggcc ccgccggaga ggtactcggc actggcgtcc
     7441 cggttcatga agtcggacat cgtggtgccc gccatgctgg tggacaggat gacggtccag
     7501 tagaagaagg ggttgtaccg ccgggaggcg agctggacga cgagcgtgac cacgaagacc
     7561 aggaacaggg cgatcgtggt caggaagtag cccagcccca tcgtctggga gaagaggtcg
     7621 ccggccgtct cgccgagcgt cgtcgcggcg atcttcatga tccagaaggc gagggtgacc
     7681 tccggcagct tcttcatgac gtaggtgccg gtgcccgcgg cctcccggtc ggtgagcagt
     7741 tccgaatcgt ccatggtgct gactcccgac atcgcggcga acaggcggac ttgggtggtt
     7801 tcgcctgtct tcagcgtccg ccaggccggc ctgccgggcg ggttgcgaca cggtgccggg
     7861 cccgctcgac cactcggccg ggtggggtgt ctggcgcaag atccggaaag tcactaacat
     7921 gcgcacgatc cggccacagt cgggtcggtc aggcaatctc ccccggcaga acgggaacgc
     7981 actccgccgc gcgagccctg ttcgcctcta ggagggaacg gtgtcgtagt cccgtaggct
     8041 ctcaagtcgc ctcactggct ggtttccatc gaccacccac tacaggacgt ggcccatccg
     8101 gtcgagcacc gttgatccct cacagggaag tagttcacgc cgcggcaggg agatctatct
     8161 agtgaaagac gtcgggtcgg tgcgaactgc cgcgttccgg ggagacgagt cccgccccgg
     8221 cgccttccag gccagcgcga gcatcgtgca ggcgggcttc ttctgctggg agatcgccac
     8281 gggcgagatc tcctgcgatc cgctcaccct cgccctgcac ggcatgcccg agcacggccc
     8341 gtcggacatc accgacttcc tggccgcggt gcacgagtcc gatctggccg acgtgcgcga
     8401 cgcgttgggg ctcatagcca agagctgcgg caactaccag atcgagtacc gcgtcacctc
     8461 cggcgacggc cggcaccggt ccctggaggc ccggggccgc gtcctgcccg gcgccgacgg
     8521 gcagccggcc cgcatggtcg gcgtggtcat ggacaccacg gccgtccacg aacgccacga
     8581 ggcggagcga cggcggttcc acgagcgcgc cacccgtgac cgctggatgc gggagctgac
     8641 cgcggccctg gccgccgcgg tgacggtcag ggacatcatg gccgccgcgc aggcgggcct
     8701 gcgcgccttc ggagcggacg cgctggcggt gatcgccccg gagggcagcc ggctgaccgt
     8761 cgtcgcctcg tgcgccgacg acgagcaggg cgaggcctcc ccgcgcgccc tcgacgccac
     8821 ggcccgcacc ctcgtggagg agtccctcga gcgcagggcg cccgttctcg tcggctccgc
     8881 ggacgcactg gtcaccgacc gcccgcacct ggcgcccctc gcgcggccgg ccccgcaggc
     8941 gtgggcggca ctgccgctca cggactcccg cggccgcgcc agttcctgcc tcgtcagctt
     9001 ccccgagccg caggagttcc tgcccgagga gcgggccctg ctggtcgccg ccgtgggact
     9061 gctcgcccag tcactggagc gagccggcat gtacgagtcg gaacacgcgc tcgccaccga
     9121 actccagcgc ggcatgctgc cgcgcggacc gctcacggtg ccgggcgtga ccatcgccgc
     9181 ccgctaccag gccgccacct ccggcatgtg gatcggcggc gactggtacg acgccatcag
     9241 cctgcccgac ggcggggtgg ccctggtcat aggagacgtg cagggacaca gcgtccacgc
     9301 cgcgtccctc atggggcggc tgcgcaccgc cgtgcacgcc tacgcgaacg agggacaccc
     9361 gccggcggcc gtgctggaac gcaccaaccg cctgctgacc gagctgaaca ccgacccgga
     9421 ccgggccctg ttcgccacct gctgctacat cgcgctgaac cctgccgacg gcacgctccg
     9481 ggtgtgccgg gcgggccatc ccgccccggc cctgatcacg ccccgcaggc cgccgcgcct
     9541 cctggaggtc cccggcggcc tgccgctggg gatcgaccgg gagcagcggt acccgaccac
     9601 ccgtctgcgc gtcgctccgg gcagcgtgct ggcgctgacc accgacggcc tgctcgaagc
     9661 cgtggacaag gacatcgacc agggcaccga gaggttcctg cggggtctgc ggggcgcccc
     9721 cacggcggac ctggagaccg tcgtcgacgg cctcctcgcc ggtacccggc ggccgcacgg
     9781 cccgggcgac gacgtcgccg tgctcctggc ccgcctgaac cggcccggcc gccgcggctg
     9841 acccggtccc ggcccacccc cgtccgcaac aggcctgtgc ggcggggtac ttgaagacgt
     9901 aacgagacct ctgtccaaca ccgccgccgg gcacggtaat ttacgtcggt ggccggactg
     9961 cctggtcatg gcagggaatc accgggaagc gagctgacgt atggacacat tccggattcc
    10021 ggacctctgc atacccgtac cggcagcgct caatccggag ctccggacgg ccacggccgc
    10081 caccgacgcg tggctggacg agttcggcct ggtgcccacc gaggaggcgc gccgccatgt
    10141 gcagcgcacc cgtgtggacc ggctcaccgc gtggctgtgc ccgaacgcct ccgcggaggc
    10201 gctgacactg atcacccagt ggaacgcgtg gctgttccag ttggacgacc agttcgacga
    10261 cgacccggtg cgcggttacc agcccgagcg gtggcgggag gcgttcggcc cgttgttcgc
    10321 cgtcttcgac ggaaccgtcg cggccgggcg gctggcgcgg tccctggccg atctgtggcg
    10381 ccgtacgacg gccgtccgat cgtccgcctg gcagcggcgc ttcgtcccgc acctgctgtg
    10441 gtacttcgac agctaccgcg ccgacatgat ccaccgcgag gaagggcgcg tacccggcct
    10501 ccagcagtat ctcgcccacc gccgcgcctc gttcgcgttc gacgccgtcc tggacctgat
    10561 ggagatcggc accggggtgg acctgcccga ccggctgcac gcgaacccgg cgttcgcgga
    10621 catgcgggag gcggtcatct acgcgaacgc ctgcgtcaac gacctgtact cgctgcgcaa
    10681 ggaactcgcg cacgactacg cgttcaacgc cgtcacggtg atcggccacc accaccggtg
    10741 cgacctccag gaggcggtgg accgcgtggc cgcgatgcag gccggatacg tccagcgcat
    10801 cctcgatctc gaacaggtcc tgcccgagcg cctgacgcgg gccggcctcg ccgacgacgt
    10861 cgccgacgac gcgctgcgct gcgtcaggga cttccacgcg ctcaccgccg ggaacgtcgc
    10921 ctggtcgaag gagaccggac gctacgcgga gatagaggcc caaccgacct atctggcaga
    10981 cctgttcatt ccgtaggaac cgtcggtcac cggcccggct ccggagcggc gcgcccggcg
    11041 aacaattccg tgcacgcccc ttgacccccc atacctacca gtcagtacgc tcacgccacc
    11101 tcaaagacac cggtgtcctc tcccctgtgc ggccacggcg aaccggcctc tcgccgtgcc
    11161 gccgcacgcc cgccggcgca cctcccgcaa cccgggagac gcgccggcgc cgtccccgcc
    11221 agaggcgccg cccagcgctt cacgacccca ccgagagtgc atcgtgaaca agaccctcat
    11281 gagcgcggcc gccgccgcgg ccggcgccct cctcgccgtg caggcgtccc tccccgccca
    11341 cgccgcgagc ggctccacct tcggctcgac cagcaacccc gtgctgttcg tgcacggtta
    11401 caccggtgcc ggcagcaact gggacaccat ggcgagccgc ttcaaaaccg acggctggcc
    11461 gtcctcgtac ctcgaccagt ggtcctacga ctggcgccag tcgaacgcca cgaccgccca
    11521 gcagctgtcc accgaggtcg accgcctcct cgcggccacc ggcgccacca aggtcgacat
    11581 cgtcagccac tccatgggcg ggctgtcctc gcgctactac ctgaagaacc tcggcggaga
    11641 ctccaaggtc gacgcctggg tgtccctggg cggcccgaac cacggcaccg acagcgccaa
    11701 cacctgcttc gacacgtcct gcaccgagat gcgcatcggc tccagcttcc tcaccgccct
    11761 caactccggc gacgagacac cgggcacgcc ccgctacgcc acctggtggt cgccctgcga
    11821 cacggtgatc aacccggaca gctccgtctc cctgtccggc gcggccaaca cccagacctc
    11881 ctgcctcagc cacacgggcc tgctcaccga cgcgacggtc tacgcccaga cccggaacat
    11941 gatcaattcc tgacccctcc atcggcctgc cccaggttgc ccggcccgca cccctccttc
    12001 acgctcggtc atgacagcgc tcacccgcga cagaaggaga atccgcatga tcgtcaactt
    12061 gctcggtgat gtcctcgcca tcctgggctg cctgctctga gacagccgaa gaaccccttc
    12121 gacggaacac cggtcggcga gcaccggtgg acctgccccg gccggccccg tacgacagca
    12181 cggggccggc ctcgggccgt gtccgacacg gcatccggac cgggtgctcc cgccggtcgg
    12241 cgggggtgac atcagccggt cggcggggtg cttccggaaa ctcgccaggt ctggtgggac
    12301 ggcccgtcgg tcatacctca gggcatgacg ctgaacgcac cgtcggcagc accgacagac
    12361 gtgtcgaacg accgcgagag gacaggctcc cccgcttcga cgggcagacc ctcgcccgcc
    12421 cccttcgacg cgatctcctt cgtcttcgcc cagagaccgt ccaccgggcg gctcgtcggc
    12481 atcgacctcg cgcgcggcct cgcggtcttc ggcatgtact ccgcgcacgt cggcccggac
    12541 gtgacggtgg gcggcccgat gggattcctg ctggaggcgg cacggggacg gtgctccgcc
    12601 ctcttcgcgc tgctggccgg tttctccctg atcatcatca ccggccgccc gtgtccgcgg
    12661 accgggcgcg ccggccggca ggcggtggcg cgggtcgtga tccgcgccgt cgtcctggcg
    12721 gtgctcggct atgcgctgac ggccctggac accgacgtgg ccgtgatcct cagcttctac
    12781 ggcctgctct tcctggcagt cctcccgctg caccggctgc gggccggggc actggccctc
    12841 gtcgccgccg cgggcgcgct ggtcatgcct ccgctgctct acgtgatcag gaactcgatc
    12901 gagcaggggc actgggcgga cgccgtcatc gcccgggatc cgctggcccg tatcaccggc
    12961 acggacggtt tcgtcgagct gctgttcacc ggcgagtacc cggtgctcac ctggatgccg
    13021 ttcctggtcg cgggcatggc cgtggcccgg ctggacctca cccgccccgg cacgcgctcc
    13081 cggctggccc tcgcgggagg ggggctggcc ctgctcggct acggcggttc ctggctggcc
    13141 ctgcgtctgg tcccgcacgc cctctccacc gtcgcggccg ccacggacgg cgggtcggcg
    13201 tcctccgcct ggtggtccga caccgtcggc gaccctgtga accacacccc gctcgactgg
    13261 ctgctggtgg cggcgccgca cagccagacg accttctccg ttctcgggaa cacgggcgtc
    13321 gccctcgcgg tggtggccgg gtgcctgacc gtcgccgacc ggatgccgcg cctcatgcgc
    13381 ctggccggac ccgtcgcggc ggtcggcaca atggcgctga cggtgtacgt cctgcacatc
    13441 gtcgccctgt ggttcctcac cgacgcctgg cgcgtgccgg cgatcgagga cgggtccctg
    13501 aacgccctgc cggtactcct cggcttcatc ctggcggcga cgatcctggc catggtctgg
    13561 actagtacgt tccggcgcgg cccgctggag tacctgctgc accaggccac ccgtcctgcc
    13621 cgctgcgtgg ggccgagggc gacgcgggct tcatcaccgg gtcgggccga gcacctcgtc
    13681 ggcgctgcgc ggctccgtgc gcggttgctg gttcagcttg tggcgcgcga tggaggaccg
    13741 ccggtagacc tccttgcggg cccgcatgat gttgccgagg ggagcgtgct cggcggtgac
    13801 cctccagggc gtgaaggaca gtgagtccat cttctccagg ttctccgggc cggagatgtc
    13861 ctgccggggc agccgcagct tggccacggt gacggacggc gagagccgtt cgggccactc
    13921 caccgtggtg tcctccaccg gcatgcgctc cagatcggtg cagagctgga tctggatgtc
    13981 gaaggtgtag ggccgctccc gcagctcggc ctccagggcc ggccggaaca cctccgccgc
    14041 cgaggccggg tcgacggcgc gccgcaccac cgcggcggcg gagtccgggt cgggggtgat
    14101 gcgcaccttg gcgatgtagt ccccgtgccg gaccgcgccc atcgtccagt agctcgacag
    14161 cagcaggttg gccggaggag tcttcgacag gcggaggaag gccaggaact cgtcccacgc
    14221 ccagtcgtcc tggtccagcg ttcccttgcc cgtcacgaac tcggtgaaga agcggtgcgc
    14281 tccgggccgg ccctgggaga agtacgccgc tgcgttcagg aacagttcct ggacgaagag
    14341 gtagtgctcg accgtgttgc agaagaagac cggtccgttg atgttggcgt agtcgaacgt
    14401 ccccgtgtcc ggttcgtctt ccagcagggt cgggccgggg atgtcgaaca tcttcagtgc
    14461 cagtccggtg gcggcgccca gtcgcgcgtc tgctccggcg tgcggggagc cgttggagaa
    14521 gcggatgagc gcgtcgtggg tgcccggggt cgcgtagatg ccctgggcgt actcgggggg
    14581 cagcccgtcc aggatctcca cctctcctcg gatcagtccg tatcccttgg cgtgggcgtc
    14641 gcggagggcc cgtcccgtgc ccccggcttc gacggactcg gcgatgtagt tctcggtctt
    14701 ctcgatcacc gtctgcacgt tccggtcgaa gtccgggtcg tcgacttcga cgtccggcgt
    14761 gtagcggacg aactgtgctg gcatgacgtc gacctcttct cgaagaccgt gaccgggcct
    14821 gagcgggtgg gagtggccgt cagtcctcca tttcggcgag ccagcgcagg gctcgcaggc
    14881 ccggcacgaa gcagtactcg ccgccgcgcg tgaccacgaa gctgggcagg ttgcgcaggc
    14941 ggcgccgcac cggcttgccg gggatggtga cgctgccggt tccgtcgtga tgtccggcca
    15001 ccgggtcctt ctcgccggga tagccgatga agttgccgtc gttgacccac tcggccttga
    15061 tgaattcaaa ctgccgttca aggtgggccc cgatgaacac tccgaccagg ccgcggtcgg
    15121 caccgtcgtc ctccagcacg ccctcgggca gcggcggacc gtaggtggtg ccgcgacgga
    15181 tgagccggtg catccgtgcg tcgccgacga tggtggcgtc gcgggggttg ttccggcgga
    15241 tgtgcgcgcc ggccgggcac cgcagaccgc gatcgtcgtg ctcgcggtac aggaagttgt
    15301 tgacacgctg cggatccgcc gccagctccg ggtcgtcgtg ctccggagcc agcgtcagcg
    15361 gtgcaccgct cggccagcgc ccgaccatct tcgccgccag gagtgcctcc tcctccgcac
    15421 tggaactgtt ggcgcgcaga taccggcgcc acgccgccac gtcggtgtga atcttgcgca
    15481 cggccacgta ggtcccgttg cgtcccagca cgtcggggcg gggcatgggc ggcagattgc
    15541 cggtctcgtc ggggtagccg aggatgaact cgccggcctt gatgggggct tcctgcggat
    15601 tggagccggg cagtccgacg ccctcgatgt tcggatggct gatgccgtcc cggaagccga
    15661 aggtggtgcg cccggtcgga agctggtgga cgtcctgctg ccagatcacc cggacaccgg
    15721 gcgtgtcctc gtaggcggca cgggcccgtt ccagctcctc gtccagctgt gccgtatccg
    15781 aggagagggc gctcagcgcg atgtggacgt cgcccgaccc gaacggtgcc tcccagtggg
    15841 ccggggcgtt cgcgcccaca tcgccgatcc gttccgccct ggcggccatg ccctcacgga
    15901 aggcccgcgg aaagctgtcc agcgaatcct gaggtacccc cagggcccgc agcccctgat
    15961 gggtgaacgc cacggccacc caggcgtccc ggctcaggtc ggcgctcggc aggccgcccg
    16021 aggtcaccgg gagcagtcgt cgcagcaggg cacgtccggc gtggcggtcg tcgacgcgca
    16081 ggaagacgaa ctttccctcg tagggcacgg gccgcgggcg cagcgccccg ctctggacgt
    16141 cctcgatctc tacgcgcaca ccggccgagc cgccgctgtc tgccgtgttc atgattgttc
    16201 gtgcctccgc atcggtcccg gttggtccag acaggcccac agcgacgggt gggcgagggg
    16261 tgcgcgcccg ccgacgcggc tcaccgttgt ggggccggct ctgagtcgtg gctgtgtccg
    16321 gctcctaggc cgaggcttct tccagcagct tctggaaggc gggcgtggcc accaactccg
    16381 cgttggccgg gttctccagg gcggcgcgga actcaggggt gtccagtacc tcctcgaacg
    16441 cctcttccac gcggtggtcc ttgtagatct gctgaacggt cagatcggga taggcgctga
    16501 cgaagactcc cgcgggggcc tggtgggcga cgaaccagtc cttcaccccc ggatcggaga
    16561 tgccggggaa cccttcgctg tgcgagaaga ccttgtcgaa gcgttccccg accaccgtct
    16621 tggcgaagtc gtcgatgtag gcgtcccagg agccgtcgaa gacgctggcg aacatgaacc
    16681 gggtgtcgtt gtcgaagatc acgtggcggg cgtcgtgcag ggtgccgatc tggcgcaccg
    16741 ccgcgtgcac tcgctcgtcg tccgccgcgt cggcgagcgt cgcgagaacc tcgcgcaacg
    16801 cgtcggcgtg gccgggcttg atctcggtga agacggtgaa ctcgctgcag accccgtccg
    16861 acctgcccgg acgctcgggg tgagcggacc gggacggttg tgccgttgca gtcatcgtga
    16921 gactcccctg ccacggatcg gtgcgagggt caccaaacgc cggagcacgg ggcgccatcg
    16981 ccctcaccac tccatcctca ccaccgatgc gcaggcgccg catctcggca cctgaggaag
    17041 gacaaccggg gtacggggcg gccgatgccc accttcgcgg cgcccgaggc tcccgaggct
    17101 cccgaggaca gatcgagcca tgagcaggag gatggtactg aggcgtgcgc gctgagcacc
    17161 ggggcgtcac ctttcggtca gtctctcccg ctgggcactg aaaccgctgc gcaaccgacc
    17221 gcacgagccc cctcctgccg cccaggcggt cggggcgccg ggctccgccg gacctcgacc
    17281 ggatcgccgc ccgaccccgg ctggaggcaa ccatgggcgc agttctcggt gacgtgctgg
    17341 gcttcgcggc cgccgtcgcg gtcagccccc tcccgatcat cgccgtcatc ctgatactcg
    17401 ccacgcctcg gggacctctc aacggcgtcc ttttcaccct cggctggatc ctgggcctgt
    17461 ccgcactggg cgcggtgatg ctggcgatcg cctcccccgc gagcgcctcc gcgaacagtc
    17521 atccggccac ctgggtggga gccctcaagc ttgcgctggg cctgttcctc gtcctcttcg
    17581 gtgcccggaa gtggcatcgc cgcccgaagg acccctcgca ggcccagctg ccgaagtgga
    17641 tgagcgcgat cgaccgcctc acaccggtca agatcttcgc gctcggactc gccctggccg
    17701 cgctcaacgc caagaacgcg ccgctgacca tcgccgcggg cgccacgatc ggctcggccg
    17761 gactgccggt ggcgcagcag gtcgcatcgc tcgccgtctt cgtcctgatc gccaccctcg
    17821 gcctcctggc tccgctggga gtcttcctcc tcggaggaga gcgagccagg gccacactcg
    17881 gcaactggaa ggactgggca gctcagcaca atgtcgccgt gatggccgtc ctgttcttcg
    17941 ttctcgggtt gaagctgctc ggtgacggca tctccgttct cgtctcctga cagagctacg
    18001 agggttaacg cacgtgcggc agaccggtgt gccgcacctc gaaccagacg gtcttgccgg
    18061 tcgccgtacg gctgctgccc caggcgtccg cgagcaggtc gaggagttcg gtgccgcgac
    18121 caccttccgc gtccgcatcc acgacgttgc gcacagggcc ggcggactcg gtgtcctcga
    18181 cctcgcacag caggcaggag ccgcacagcc gcaggttgag ccgcagcggg ccccgcgtgt
    18241 gacgcaaggc gttggtgacc acttcgctga ccagcagctc gacggcgtcg gccaggtcgt
    18301 ccacggacca gtcgcccagt tgcctggtca ccagatgccg ggcctggcgc acggaagtga
    18361 gttcccgcgg cagcggccag gaggcatccc atgcggaggc ccggccgcgc ggcgcgtcca
    18421 gcggccgcaa gggtgcgagc atccgggacc acaggaccca ctgcgtggca agccacgagc
    18481 gcgtgacgga gcgagaagac cgacccctgc gacgggcgag ggggcggcct acggcctggg
    18541 gcatcacggg gtccagttcc ttccggggcg gggtggacga gccgccggtg gacgctccgg
    18601 ggtattcgcc ggacccgtac atgtagcggt cgctacgacc aatatagacg tagcacctgc
    18661 tacggtaaat acctccccaa aaggtccatg acggacaaca gacggctacc gtctccccac
    18721 acatccggga acccgcatgc ctcgcccacc cgacccggcc aaacgccgcg accttctcga
    18781 ccggatccgc gcgtacgtgc tgcgcaacgg cctctcggat ctctccctgc gcccgttggc
    18841 ccgcgccctg ggcaccagcg accgcatgct cctgtactac ttcggcacca aggaacgcat
    18901 ggtcgccgaa gcactcgccg tctacgaacg ccgccccctg ctgcgcgccc gcgaactgct
    18961 ggagaccgtc ggcccgccca cggacccggc aggcctgcgc cgcttcatgg aggaagtctg
    19021 gcgccaattc cgagcctcgg acgtgcgcgc ctcactccct ctctacctcg agatcatgag
    19081 tgccggcgtg ctgcacccgg accgctacgg gccggtgatg cgcgacatcg tcaccggatg
    19141 gacggagctg ctcgcctccg tcttccgtga actaggcatg acacgagacg gagcccggac
    19201 acaggccacc gtcctggccg acgccgcctt aggcctcctg atcgcccccc tcgccgacgg
    19261 ccactgggac agggcggaca cagccttccg caccctcctg gacgccctgg agcccggatg
    19321 gcacgcccgg gagtgacggc cccgagggca cacggctacg accgaccagg agacctcgga
    19381 gaccccgacg gacaggaatg cgaagcgccg gcttcccccc acgcggcagc cacttcctcg
    19441 ctcacccccg ccggcgcctc cctcacccga tcgggtgctc cgctcacctc agtgcgcgtg
    19501 accgctcgca gccggcgtcg gccccgcgtt cttgaccgtc agcggcagca acttcttgcc
    19561 ggtcgggccg atttgtatgg ccgtatccat ctgcgggcac accccgcagt cgaagcacgg
    19621 cgtccagcgg cagtcctcga cctctgtctc gtcgagggcg tcctgccagt cctcccagag
    19681 ccagtccttg tcgaggcccg agtcgaggtg gtcccagggg aggacctcct cgtaggtgcg
    19741 ttcgcgcgtg gtgtaccagt cgacgtcgac gccgaagggg gccagggcct tgtcggcgca
    19801 ggccatccag cggtcgtagg agaagtgctc gcgccagccg tcgaagcggc cgccgtcttc
    19861 gtagacggcg cggatgacgg cgccgatgcg gcggtcgccc ctcgacagca ggccctccac
    19921 gatgcccggc ttgccgtcgt ggtagcggaa gccgatggag cggccgtact tcttgtcgcc
    19981 gcggatcttg tcgcggagct tgccgaggcg ggcgtccgtc tcctcggcgg agagctgcgg
    20041 ggcccactgg aagggggtgt ggggcttggg gacgaagccg ccgatggaga ccgtgcagcg
    20101 gatgtcgttg gagccggaga cctcgcggcc cttctggatc acgcgggtcg ccatgtcggc
    20161 gatctggagg acgtcgtcgt cggtctccgt cggcaggccg cacatgaagt acagcttcac
    20221 ctggcgccag ccgttgccgt aggccgtcgc gaccgtgcgg atgaggtcgt cctccgagac
    20281 catcttgttg atgaccttgc ggatgcgctc ggagccgccc tcgggggcga aggtcaggcc
    20341 ggagcggcgg ccgttgcggg tcagctcgtt cgccaggtcg atgttgaagg cgtcgacccg
    20401 ggtggagggc agggagaggc cgatcttgtc gtcctcgtag cggtcggcga ggcccttggc
    20461 gatgtcgccg atctccgagt ggtccgcgga ggacagggag agcaggccca cctcctcgaa
    20521 gcccgtggcc ttcaggccct tgtcgaccat ctcgccgatg ccggtgatcg agcgctcgcg
    20581 gaccgggcgg gtgatcatgc cggcctggca gaagcggcag ccgcgggtgc agccgcggaa
    20641 gatctcgacc gacatgcgct cgtggacggt ctccgcgagg gggacgaggg gctgcttggg
    20701 gtagggccac tcgtccaggt ccatgaccgt gtgcttggac acgcgccacg ggacgcccga
    20761 cctgttgggg acgacgcggg cgatgcggcc gtcggggagg tactcgacgt cgtagaacgc
    20821 cgggatgtac accccgcccg tcttcgccag gcggaacagg agttcctcgc ggccgccggg
    20881 gcggccctcg gccttccagg cgcggacgat gcgggtcatg tcgaggacgg cctgctcgcc
    20941 gtcgccgatc acggccgcgt cgatgaagtc ggcgatcggc tcggggttga acgcgg
//
